The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination and contributes to DSB repair within heterochromatin
Identifieur interne : 000346 ( Main/Exploration ); précédent : 000345; suivant : 000347The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination and contributes to DSB repair within heterochromatin
Auteurs : Gabriel Kollárovi ; Caitríona E. Topping ; Edward P. Shaw ; Anna L. ChambersSource :
- Nucleic Acids Research [ 0305-1048 ] ; 2019.
Abstract
Efficient double-strand break repair in eukaryotes requires manipulation of chromatin structure. ATP-dependent chromatin remodelling enzymes facilitate different DNA repair pathways, during different stages of the cell cycle and in varied chromatin environments. The contribution of remodelling factors to double-strand break repair within heterochromatin during G2 is unclear. The human HELLS protein is a Snf2-like chromatin remodeller family member and is mutated or misregulated in several cancers and some cases of ICF syndrome. HELLS has been implicated in the DNA damage response, but its mechanistic function in repair is not well understood. We discover that HELLS facilitates homologous recombination at two-ended breaks and contributes to repair within heterochromatic regions during G2. HELLS promotes initiation of HR by facilitating end-resection and accumulation of CtIP at IR-induced foci. We identify an interaction between HELLS and CtIP and establish that the ATPase domain of HELLS is required to promote DSB repair. This function of HELLS in maintenance of genome stability is likely to contribute to its role in cancer biology and demonstrates that different chromatin remodelling activities are required for efficient repair in specific genomic contexts.
Url:
DOI: 10.1093/nar/gkz1146
PubMed: 31802118
PubMed Central: 7038987
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000732
- to stream Pmc, to step Curation: 000732
- to stream Pmc, to step Checkpoint: 000309
- to stream Ncbi, to step Merge: 000C81
- to stream Ncbi, to step Curation: 000C81
- to stream Ncbi, to step Checkpoint: 000C81
- to stream Main, to step Merge: 000346
- to stream Main, to step Curation: 000346
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination and contributes to DSB repair within heterochromatin</title><author><name sortKey="Kollarovi, Gabriel" sort="Kollarovi, Gabriel" uniqKey="Kollarovi G" first="Gabriel" last="Kollárovi">Gabriel Kollárovi</name><affiliation><nlm:aff id="AFF1"></nlm:aff></affiliation></author><author><name sortKey="Topping, Caitriona E" sort="Topping, Caitriona E" uniqKey="Topping C" first="Caitríona E" last="Topping">Caitríona E. Topping</name><affiliation><nlm:aff id="AFF1"></nlm:aff></affiliation></author><author><name sortKey="Shaw, Edward P" sort="Shaw, Edward P" uniqKey="Shaw E" first="Edward P" last="Shaw">Edward P. Shaw</name><affiliation><nlm:aff id="AFF1"></nlm:aff></affiliation></author><author><name sortKey="Chambers, Anna L" sort="Chambers, Anna L" uniqKey="Chambers A" first="Anna L" last="Chambers">Anna L. Chambers</name><affiliation><nlm:aff id="AFF1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">31802118</idno><idno type="pmc">7038987</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038987</idno><idno type="RBID">PMC:7038987</idno><idno type="doi">10.1093/nar/gkz1146</idno><date when="2019">2019</date><idno type="wicri:Area/Pmc/Corpus">000732</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000732</idno><idno type="wicri:Area/Pmc/Curation">000732</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000732</idno><idno type="wicri:Area/Pmc/Checkpoint">000309</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000309</idno><idno type="wicri:Area/Ncbi/Merge">000C81</idno><idno type="wicri:Area/Ncbi/Curation">000C81</idno><idno type="wicri:Area/Ncbi/Checkpoint">000C81</idno><idno type="wicri:doubleKey">0305-1048:2019:Kollarovi G:the:human:hells</idno><idno type="wicri:Area/Main/Merge">000346</idno><idno type="wicri:Area/Main/Curation">000346</idno><idno type="wicri:Area/Main/Exploration">000346</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination and contributes to DSB repair within heterochromatin</title><author><name sortKey="Kollarovi, Gabriel" sort="Kollarovi, Gabriel" uniqKey="Kollarovi G" first="Gabriel" last="Kollárovi">Gabriel Kollárovi</name><affiliation><nlm:aff id="AFF1"></nlm:aff></affiliation></author><author><name sortKey="Topping, Caitriona E" sort="Topping, Caitriona E" uniqKey="Topping C" first="Caitríona E" last="Topping">Caitríona E. Topping</name><affiliation><nlm:aff id="AFF1"></nlm:aff></affiliation></author><author><name sortKey="Shaw, Edward P" sort="Shaw, Edward P" uniqKey="Shaw E" first="Edward P" last="Shaw">Edward P. Shaw</name><affiliation><nlm:aff id="AFF1"></nlm:aff></affiliation></author><author><name sortKey="Chambers, Anna L" sort="Chambers, Anna L" uniqKey="Chambers A" first="Anna L" last="Chambers">Anna L. Chambers</name><affiliation><nlm:aff id="AFF1"></nlm:aff></affiliation></author></analytic><series><title level="j">Nucleic Acids Research</title><idno type="ISSN">0305-1048</idno><idno type="eISSN">1362-4962</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Abstract</title><p>Efficient double-strand break repair in eukaryotes requires manipulation of chromatin structure. ATP-dependent chromatin remodelling enzymes facilitate different DNA repair pathways, during different stages of the cell cycle and in varied chromatin environments. The contribution of remodelling factors to double-strand break repair within heterochromatin during G2 is unclear. The human HELLS protein is a Snf2-like chromatin remodeller family member and is mutated or misregulated in several cancers and some cases of ICF syndrome. HELLS has been implicated in the DNA damage response, but its mechanistic function in repair is not well understood. We discover that HELLS facilitates homologous recombination at two-ended breaks and contributes to repair within heterochromatic regions during G2. HELLS promotes initiation of HR by facilitating end-resection and accumulation of CtIP at IR-induced foci. We identify an interaction between HELLS and CtIP and establish that the ATPase domain of HELLS is required to promote DSB repair. This function of HELLS in maintenance of genome stability is likely to contribute to its role in cancer biology and demonstrates that different chromatin remodelling activities are required for efficient repair in specific genomic contexts.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Jackson, S P" uniqKey="Jackson S">S.P. Jackson</name></author><author><name sortKey="Bartek, J" uniqKey="Bartek J">J. Bartek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Filippo, S" uniqKey="Filippo S">S. Filippo</name></author><author><name sortKey="San Filippo, J" uniqKey="San Filippo J">J. San Filippo</name></author><author><name sortKey="Sung, P" uniqKey="Sung P">P. Sung</name></author><author><name sortKey="Klein, H" uniqKey="Klein H">H. Klein</name></author><author><name sortKey="Filippo, S" uniqKey="Filippo S">S. Filippo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Trenz, K" uniqKey="Trenz K">K. Trenz</name></author><author><name sortKey="Smith, E" uniqKey="Smith E">E. Smith</name></author><author><name sortKey="Smith, S" uniqKey="Smith S">S. Smith</name></author><author><name sortKey="Costanzo, V" uniqKey="Costanzo V">V. Costanzo</name></author><author><name sortKey="Iwasaki, H" uniqKey="Iwasaki H">H. Iwasaki</name></author><author><name sortKey="Arcangioli, B" uniqKey="Arcangioli B">B. Arcangioli</name></author><author><name sortKey="Jackson, S" uniqKey="Jackson S">S. Jackson</name></author><author><name sortKey="Blundell, T" uniqKey="Blundell T">T. Blundell</name></author><author><name sortKey="Morrice, N" uniqKey="Morrice N">N. Morrice</name></author><author><name sortKey="Jeggo, P" uniqKey="Jeggo P">P. Jeggo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Beucher, A" uniqKey="Beucher A">A. Beucher</name></author><author><name sortKey="Birraux, J" uniqKey="Birraux J">J. Birraux</name></author><author><name sortKey="Tchouandong, L" uniqKey="Tchouandong L">L. Tchouandong</name></author><author><name sortKey="Barton, O" uniqKey="Barton O">O. Barton</name></author><author><name sortKey="Shibata, A" uniqKey="Shibata A">A. Shibata</name></author><author><name sortKey="Conrad, S" uniqKey="Conrad S">S. Conrad</name></author><author><name sortKey="Goodarzi, A A" uniqKey="Goodarzi A">A.A. Goodarzi</name></author><author><name sortKey="Krempler, A" uniqKey="Krempler A">A. Krempler</name></author><author><name sortKey="Jeggo, P A" uniqKey="Jeggo P">P.A. Jeggo</name></author><author><name sortKey="Lobrich, M" uniqKey="Lobrich M">M. Löbrich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Limbo, O" uniqKey="Limbo O">O. Limbo</name></author><author><name sortKey="Chahwan, C" uniqKey="Chahwan C">C. Chahwan</name></author><author><name sortKey="Yamada, Y" uniqKey="Yamada Y">Y. Yamada</name></author><author><name sortKey="De Bruin, R A" uniqKey="De Bruin R">R.A. de Bruin</name></author><author><name sortKey="Wittenberg, C" uniqKey="Wittenberg C">C. Wittenberg</name></author><author><name sortKey="Russell, P" uniqKey="Russell P">P. Russell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sartori, A A" uniqKey="Sartori A">A.A. Sartori</name></author><author><name sortKey="Lukas, C" uniqKey="Lukas C">C. Lukas</name></author><author><name sortKey="Coates, J" uniqKey="Coates J">J. Coates</name></author><author><name sortKey="Mistrik, M" uniqKey="Mistrik M">M. Mistrik</name></author><author><name sortKey="Fu, S" uniqKey="Fu S">S. Fu</name></author><author><name sortKey="Bartek, J" uniqKey="Bartek J">J. Bartek</name></author><author><name sortKey="Baer, R" uniqKey="Baer R">R. Baer</name></author><author><name sortKey="Lukas, J" uniqKey="Lukas J">J. Lukas</name></author><author><name sortKey="Jackson, S P" uniqKey="Jackson S">S.P. Jackson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="You, Z" uniqKey="You Z">Z. You</name></author><author><name sortKey="Shi, L Z" uniqKey="Shi L">L.Z. Shi</name></author><author><name sortKey="Zhu, Q" uniqKey="Zhu Q">Q. Zhu</name></author><author><name sortKey="Wu, P" uniqKey="Wu P">P. Wu</name></author><author><name sortKey="Zhang, Y W W" uniqKey="Zhang Y">Y.-W.W. Zhang</name></author><author><name sortKey="Basilio, A" uniqKey="Basilio A">A. Basilio</name></author><author><name sortKey="Tonnu, N" uniqKey="Tonnu N">N. Tonnu</name></author><author><name sortKey="Verma, I M" uniqKey="Verma I">I.M. Verma</name></author><author><name sortKey="Berns, M W" uniqKey="Berns M">M.W. Berns</name></author><author><name sortKey="Hunter, T" uniqKey="Hunter T">T. Hunter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gravel, S" uniqKey="Gravel S">S. Gravel</name></author><author><name sortKey="Chapman, J R" uniqKey="Chapman J">J.R. Chapman</name></author><author><name sortKey="Magill, C" uniqKey="Magill C">C. Magill</name></author><author><name sortKey="Jackson, S P" uniqKey="Jackson S">S.P. Jackson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Budd, M E" uniqKey="Budd M">M.E. Budd</name></author><author><name sortKey="Campbell, J L" uniqKey="Campbell J">J.L. Campbell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Allshire, R C" uniqKey="Allshire R">R.C. Allshire</name></author><author><name sortKey="Madhani, H D" uniqKey="Madhani H">H.D. Madhani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goodarzi, A A" uniqKey="Goodarzi A">A.A. Goodarzi</name></author><author><name sortKey="Noon, A T" uniqKey="Noon A">A.T. Noon</name></author><author><name sortKey="Deckbar, D" uniqKey="Deckbar D">D. Deckbar</name></author><author><name sortKey="Ziv, Y" uniqKey="Ziv Y">Y. Ziv</name></author><author><name sortKey="Shiloh, Y" uniqKey="Shiloh Y">Y. Shiloh</name></author><author><name sortKey="Lobrich, M" uniqKey="Lobrich M">M. Lobrich</name></author><author><name sortKey="Jeggo, P A" uniqKey="Jeggo P">P.A. Jeggo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woodbine, L" uniqKey="Woodbine L">L. Woodbine</name></author><author><name sortKey="Brunton, H" uniqKey="Brunton H">H. Brunton</name></author><author><name sortKey="Goodarzi, A A" uniqKey="Goodarzi A">A.A. Goodarzi</name></author><author><name sortKey="Shibata, A" uniqKey="Shibata A">A. Shibata</name></author><author><name sortKey="Jeggo, P A" uniqKey="Jeggo P">P.A. Jeggo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schuster Bockler, B" uniqKey="Schuster Bockler B">B. Schuster-Böckler</name></author><author><name sortKey="Lehner, B" uniqKey="Lehner B">B. Lehner</name></author><author><name sortKey="Schuster Bockler, B" uniqKey="Schuster Bockler B">B. Schuster-Bockler</name></author><author><name sortKey="Lehner, B" uniqKey="Lehner B">B. Lehner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lobrich, M" uniqKey="Lobrich M">M. Lobrich</name></author><author><name sortKey="Shibata, A" uniqKey="Shibata A">A. Shibata</name></author><author><name sortKey="Beucher, A" uniqKey="Beucher A">A. Beucher</name></author><author><name sortKey="Fisher, A" uniqKey="Fisher A">A. Fisher</name></author><author><name sortKey="Ensminger, M" uniqKey="Ensminger M">M. Ensminger</name></author><author><name sortKey="Goodarzi, A A" uniqKey="Goodarzi A">A.A. Goodarzi</name></author><author><name sortKey="Barton, O" uniqKey="Barton O">O. Barton</name></author><author><name sortKey="Jeggo, P A" uniqKey="Jeggo P">P.A. Jeggo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Riballo, E" uniqKey="Riballo E">E. Riballo</name></author><author><name sortKey="Kuhne, M" uniqKey="Kuhne M">M. Kuhne</name></author><author><name sortKey="Rief, N" uniqKey="Rief N">N. Rief</name></author><author><name sortKey="Doherty, A" uniqKey="Doherty A">A. Doherty</name></author><author><name sortKey="Smith, G C" uniqKey="Smith G">G.C. Smith</name></author><author><name sortKey="Recio, M J" uniqKey="Recio M">M.J. Recio</name></author><author><name sortKey="Reis, C" uniqKey="Reis C">C. Reis</name></author><author><name sortKey="Dahm, K" uniqKey="Dahm K">K. Dahm</name></author><author><name sortKey="Fricke, A" uniqKey="Fricke A">A. Fricke</name></author><author><name sortKey="Krempler, A" uniqKey="Krempler A">A. Krempler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Clapier, C R" uniqKey="Clapier C">C.R. Clapier</name></author><author><name sortKey="Iwasa, J" uniqKey="Iwasa J">J. Iwasa</name></author><author><name sortKey="Cairns, B R" uniqKey="Cairns B">B.R. Cairns</name></author><author><name sortKey="Peterson, C L" uniqKey="Peterson C">C.L. Peterson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jeggo, P A" uniqKey="Jeggo P">P.A. Jeggo</name></author><author><name sortKey="Downs, J A" uniqKey="Downs J">J.A. Downs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goodarzi, A A" uniqKey="Goodarzi A">A.A. Goodarzi</name></author><author><name sortKey="Kurka, T" uniqKey="Kurka T">T. Kurka</name></author><author><name sortKey="Jeggo, P A" uniqKey="Jeggo P">P.A. Jeggo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klement, K" uniqKey="Klement K">K. Klement</name></author><author><name sortKey="Luijsterburg, M S" uniqKey="Luijsterburg M">M.S. Luijsterburg</name></author><author><name sortKey="Pinder, J B" uniqKey="Pinder J">J.B. Pinder</name></author><author><name sortKey="Cena, C S" uniqKey="Cena C">C.S. Cena</name></author><author><name sortKey="Del Nero, V" uniqKey="Del Nero V">V. Del Nero</name></author><author><name sortKey="Wintersinger, C M" uniqKey="Wintersinger C">C.M. Wintersinger</name></author><author><name sortKey="Dellaire, G" uniqKey="Dellaire G">G. Dellaire</name></author><author><name sortKey="Van Attikum, H" uniqKey="Van Attikum H">H. van Attikum</name></author><author><name sortKey="Goodarzi, A A" uniqKey="Goodarzi A">A.A. Goodarzi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Flaus, A" uniqKey="Flaus A">A. Flaus</name></author><author><name sortKey="Martin, D M" uniqKey="Martin D">D.M. Martin</name></author><author><name sortKey="Barton, G J" uniqKey="Barton G">G.J. Barton</name></author><author><name sortKey="Owen Hughes, T" uniqKey="Owen Hughes T">T. Owen-Hughes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, D W" uniqKey="Lee D">D.W. Lee</name></author><author><name sortKey="Zhang, K" uniqKey="Zhang K">K. Zhang</name></author><author><name sortKey="Ning, Z Q" uniqKey="Ning Z">Z.Q. Ning</name></author><author><name sortKey="Raabe, E H" uniqKey="Raabe E">E.H. Raabe</name></author><author><name sortKey="Tintner, S" uniqKey="Tintner S">S. Tintner</name></author><author><name sortKey="Wieland, R" uniqKey="Wieland R">R. Wieland</name></author><author><name sortKey="Wilkins, B J" uniqKey="Wilkins B">B.J. Wilkins</name></author><author><name sortKey="Kim, J M" uniqKey="Kim J">J.M. Kim</name></author><author><name sortKey="Blough, R I" uniqKey="Blough R">R.I. Blough</name></author><author><name sortKey="Arceci, R J" uniqKey="Arceci R">R.J. Arceci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Geiman, T M" uniqKey="Geiman T">T.M. Geiman</name></author><author><name sortKey="Durum, S K" uniqKey="Durum S">S.K. Durum</name></author><author><name sortKey="Muegge, K" uniqKey="Muegge K">K. Muegge</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raabe, E H" uniqKey="Raabe E">E.H. Raabe</name></author><author><name sortKey="Abdurrahman, L" uniqKey="Abdurrahman L">L. Abdurrahman</name></author><author><name sortKey="Behbehani, G" uniqKey="Behbehani G">G. Behbehani</name></author><author><name sortKey="Arceci, R J" uniqKey="Arceci R">R.J. Arceci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Burrage, J" uniqKey="Burrage J">J. Burrage</name></author><author><name sortKey="Termanis, A" uniqKey="Termanis A">A. Termanis</name></author><author><name sortKey="Geissner, A" uniqKey="Geissner A">A. Geissner</name></author><author><name sortKey="Myant, K" uniqKey="Myant K">K. Myant</name></author><author><name sortKey="Gordon, K" uniqKey="Gordon K">K. Gordon</name></author><author><name sortKey="Stancheva, I" uniqKey="Stancheva I">I. Stancheva</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brzeski, J" uniqKey="Brzeski J">J. Brzeski</name></author><author><name sortKey="Jerzmanowski, A" uniqKey="Jerzmanowski A">A. Jerzmanowski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jenness, C" uniqKey="Jenness C">C. Jenness</name></author><author><name sortKey="Giunta, S" uniqKey="Giunta S">S. Giunta</name></author><author><name sortKey="Muller, M M" uniqKey="Muller M">M.M. Müller</name></author><author><name sortKey="Kimura, H" uniqKey="Kimura H">H. Kimura</name></author><author><name sortKey="Muir, T W" uniqKey="Muir T">T.W. Muir</name></author><author><name sortKey="Funabiki, H" uniqKey="Funabiki H">H. Funabiki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Von Eyss, B" uniqKey="Von Eyss B">B. Von Eyss</name></author><author><name sortKey="Maaskola, J" uniqKey="Maaskola J">J. Maaskola</name></author><author><name sortKey="Memczak, S" uniqKey="Memczak S">S. Memczak</name></author><author><name sortKey="Mollmann, K" uniqKey="Mollmann K">K. Möllmann</name></author><author><name sortKey="Schuetz, A" uniqKey="Schuetz A">A. Schuetz</name></author><author><name sortKey="Loddenkemper, C" uniqKey="Loddenkemper C">C. Loddenkemper</name></author><author><name sortKey="Tanh, M D" uniqKey="Tanh M">M.D. Tanh</name></author><author><name sortKey="Otto, A" uniqKey="Otto A">A. Otto</name></author><author><name sortKey="Muegge, K" uniqKey="Muegge K">K. Muegge</name></author><author><name sortKey="Heinemann, U" uniqKey="Heinemann U">U. Heinemann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yano, M" uniqKey="Yano M">M. Yano</name></author><author><name sortKey="Ouchida, M" uniqKey="Ouchida M">M. Ouchida</name></author><author><name sortKey="Shigematsu, H" uniqKey="Shigematsu H">H. Shigematsu</name></author><author><name sortKey="Tanaka, N" uniqKey="Tanaka N">N. Tanaka</name></author><author><name sortKey="Ichimura, K" uniqKey="Ichimura K">K. Ichimura</name></author><author><name sortKey="Kobayashi, K" uniqKey="Kobayashi K">K. Kobayashi</name></author><author><name sortKey="Inaki, Y" uniqKey="Inaki Y">Y. Inaki</name></author><author><name sortKey="Toyooka, S" uniqKey="Toyooka S">S. Toyooka</name></author><author><name sortKey="Tsukuda, K" uniqKey="Tsukuda K">K. Tsukuda</name></author><author><name sortKey="Shimizu, N" uniqKey="Shimizu N">N. Shimizu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keyes, W M" uniqKey="Keyes W">W.M. Keyes</name></author><author><name sortKey="Pecoraro, M" uniqKey="Pecoraro M">M. Pecoraro</name></author><author><name sortKey="Aranda, V" uniqKey="Aranda V">V. Aranda</name></author><author><name sortKey="Vernersson Lindahl, E" uniqKey="Vernersson Lindahl E">E. Vernersson-Lindahl</name></author><author><name sortKey="Li, W" uniqKey="Li W">W. Li</name></author><author><name sortKey="Vogel, H" uniqKey="Vogel H">H. Vogel</name></author><author><name sortKey="Guo, X" uniqKey="Guo X">X. Guo</name></author><author><name sortKey="Garcia, E L" uniqKey="Garcia E">E.L. Garcia</name></author><author><name sortKey="Michurina, T V" uniqKey="Michurina T">T. V Michurina</name></author><author><name sortKey="Enikolopov, G" uniqKey="Enikolopov G">G. Enikolopov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Janus, J R" uniqKey="Janus J">J.R. Janus</name></author><author><name sortKey="Laborde, R R" uniqKey="Laborde R">R.R. Laborde</name></author><author><name sortKey="Greenberg, A J" uniqKey="Greenberg A">A.J. Greenberg</name></author><author><name sortKey="Wang, V W" uniqKey="Wang V">V.W. Wang</name></author><author><name sortKey="Wei, W" uniqKey="Wei W">W. Wei</name></author><author><name sortKey="Trier, A" uniqKey="Trier A">A. Trier</name></author><author><name sortKey="Olsen, S M" uniqKey="Olsen S">S.M. Olsen</name></author><author><name sortKey="Moore, E J" uniqKey="Moore E">E.J. Moore</name></author><author><name sortKey="Olsen, K D" uniqKey="Olsen K">K.D. Olsen</name></author><author><name sortKey="Smith, D I" uniqKey="Smith D">D.I. Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, H E" uniqKey="Kim H">H.E. Kim</name></author><author><name sortKey="Symanowski, J T" uniqKey="Symanowski J">J.T. Symanowski</name></author><author><name sortKey="Samlowski, E E" uniqKey="Samlowski E">E.E. Samlowski</name></author><author><name sortKey="Gonzales, J" uniqKey="Gonzales J">J. Gonzales</name></author><author><name sortKey="Ryu, B" uniqKey="Ryu B">B. Ryu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thijssen, P E" uniqKey="Thijssen P">P.E. Thijssen</name></author><author><name sortKey="Ito, Y" uniqKey="Ito Y">Y. Ito</name></author><author><name sortKey="Grillo, G" uniqKey="Grillo G">G. Grillo</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J. Wang</name></author><author><name sortKey="Velasco, G" uniqKey="Velasco G">G. Velasco</name></author><author><name sortKey="Nitta, H" uniqKey="Nitta H">H. Nitta</name></author><author><name sortKey="Unoki, M" uniqKey="Unoki M">M. Unoki</name></author><author><name sortKey="Yoshihara, M" uniqKey="Yoshihara M">M. Yoshihara</name></author><author><name sortKey="Suyama, M" uniqKey="Suyama M">M. Suyama</name></author><author><name sortKey="Sun, Y" uniqKey="Sun Y">Y. Sun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sun, L Q" uniqKey="Sun L">L.Q. Sun</name></author><author><name sortKey="Lee, D W" uniqKey="Lee D">D.W. Lee</name></author><author><name sortKey="Zhang, Q" uniqKey="Zhang Q">Q. Zhang</name></author><author><name sortKey="Xiao, W" uniqKey="Xiao W">W. Xiao</name></author><author><name sortKey="Raabe, E H" uniqKey="Raabe E">E.H. Raabe</name></author><author><name sortKey="Meeker, A" uniqKey="Meeker A">A. Meeker</name></author><author><name sortKey="Miao, D" uniqKey="Miao D">D. Miao</name></author><author><name sortKey="Huso, D L" uniqKey="Huso D">D.L. Huso</name></author><author><name sortKey="Arceci, R J" uniqKey="Arceci R">R.J. Arceci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fan, T" uniqKey="Fan T">T. Fan</name></author><author><name sortKey="Yan, Q" uniqKey="Yan Q">Q. Yan</name></author><author><name sortKey="Huang, J" uniqKey="Huang J">J. Huang</name></author><author><name sortKey="Austin, S" uniqKey="Austin S">S. Austin</name></author><author><name sortKey="Cho, E" uniqKey="Cho E">E. Cho</name></author><author><name sortKey="Ferris, D" uniqKey="Ferris D">D. Ferris</name></author><author><name sortKey="Muegge, K" uniqKey="Muegge K">K. Muegge</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dennis, K" uniqKey="Dennis K">K. Dennis</name></author><author><name sortKey="Fan, T" uniqKey="Fan T">T. Fan</name></author><author><name sortKey="Geiman, T" uniqKey="Geiman T">T. Geiman</name></author><author><name sortKey="Yan, Q" uniqKey="Yan Q">Q. Yan</name></author><author><name sortKey="Muegge, K" uniqKey="Muegge K">K. Muegge</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Myant, K" uniqKey="Myant K">K. Myant</name></author><author><name sortKey="Stancheva, I" uniqKey="Stancheva I">I. Stancheva</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muegge, K" uniqKey="Muegge K">K. Muegge</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yan, Q" uniqKey="Yan Q">Q. Yan</name></author><author><name sortKey="Cho, E" uniqKey="Cho E">E. Cho</name></author><author><name sortKey="Lockett, S" uniqKey="Lockett S">S. Lockett</name></author><author><name sortKey="Muegge, K" uniqKey="Muegge K">K. Muegge</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Litwin, I" uniqKey="Litwin I">I. Litwin</name></author><author><name sortKey="Bakowski, T" uniqKey="Bakowski T">T. Bakowski</name></author><author><name sortKey="Maciaszczyk Dziubinska, E" uniqKey="Maciaszczyk Dziubinska E">E. Maciaszczyk-Dziubinska</name></author><author><name sortKey="Wysocki, R" uniqKey="Wysocki R">R. Wysocki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alvaro, D" uniqKey="Alvaro D">D. Alvaro</name></author><author><name sortKey="Lisby, M" uniqKey="Lisby M">M. Lisby</name></author><author><name sortKey="Rothstein, R" uniqKey="Rothstein R">R. Rothstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kao, G D" uniqKey="Kao G">G.D. Kao</name></author><author><name sortKey="Mckenna, W G" uniqKey="Mckenna W">W.G. McKenna</name></author><author><name sortKey="Yen, T J" uniqKey="Yen T">T.J. Yen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shibata, A" uniqKey="Shibata A">A. Shibata</name></author><author><name sortKey="Conrad, S" uniqKey="Conrad S">S. Conrad</name></author><author><name sortKey="Birraux, J" uniqKey="Birraux J">J. Birraux</name></author><author><name sortKey="Geuting, V" uniqKey="Geuting V">V. Geuting</name></author><author><name sortKey="Barton, O" uniqKey="Barton O">O. Barton</name></author><author><name sortKey="Ismail, A" uniqKey="Ismail A">A. Ismail</name></author><author><name sortKey="Kakarougkas, A" uniqKey="Kakarougkas A">A. Kakarougkas</name></author><author><name sortKey="Meek, K" uniqKey="Meek K">K. Meek</name></author><author><name sortKey="Taucher Scholz, G" uniqKey="Taucher Scholz G">G. Taucher-Scholz</name></author><author><name sortKey="Lobrich, M" uniqKey="Lobrich M">M. Löbrich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Laurent, B C" uniqKey="Laurent B">B.C. Laurent</name></author><author><name sortKey="Treich, I" uniqKey="Treich I">I. Treich</name></author><author><name sortKey="Carlson, M" uniqKey="Carlson M">M. Carlson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dong, S" uniqKey="Dong S">S. Dong</name></author><author><name sortKey="Han, J" uniqKey="Han J">J. Han</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H. Chen</name></author><author><name sortKey="Liu, T" uniqKey="Liu T">T. Liu</name></author><author><name sortKey="Huen, M S Y" uniqKey="Huen M">M.S.Y. Huen</name></author><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y. Yang</name></author><author><name sortKey="Guo, C" uniqKey="Guo C">C. Guo</name></author><author><name sortKey="Huang, J" uniqKey="Huang J">J. Huang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Farmer, H" uniqKey="Farmer H">H. Farmer</name></author><author><name sortKey="Mccabe, N" uniqKey="Mccabe N">N. McCabe</name></author><author><name sortKey="Lord, C J" uniqKey="Lord C">C.J. Lord</name></author><author><name sortKey="Tutt, A N J" uniqKey="Tutt A">A.N.J. Tutt</name></author><author><name sortKey="Johnson, D A" uniqKey="Johnson D">D.A. Johnson</name></author><author><name sortKey="Richardson, T B" uniqKey="Richardson T">T.B. Richardson</name></author><author><name sortKey="Santarosa, M" uniqKey="Santarosa M">M. Santarosa</name></author><author><name sortKey="Dillon, K J" uniqKey="Dillon K">K.J. Dillon</name></author><author><name sortKey="Hickson, I" uniqKey="Hickson I">I. Hickson</name></author><author><name sortKey="Knights, C" uniqKey="Knights C">C. Knights</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mccabe, N" uniqKey="Mccabe N">N. McCabe</name></author><author><name sortKey="Turner, N C" uniqKey="Turner N">N.C. Turner</name></author><author><name sortKey="Lord, C J" uniqKey="Lord C">C.J. Lord</name></author><author><name sortKey="Kluzek, K" uniqKey="Kluzek K">K. Kluzek</name></author><author><name sortKey="Bialkowska, A" uniqKey="Bialkowska A">A. Białkowska</name></author><author><name sortKey="Swift, S" uniqKey="Swift S">S. Swift</name></author><author><name sortKey="Giavara, S" uniqKey="Giavara S">S. Giavara</name></author><author><name sortKey="O Onnor, M J" uniqKey="O Onnor M">M.J. O’Connor</name></author><author><name sortKey="Tutt, A N" uniqKey="Tutt A">A.N. Tutt</name></author><author><name sortKey="Zdzienicka, M Z" uniqKey="Zdzienicka M">M.Z. Zdzienicka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bryant, H E" uniqKey="Bryant H">H.E. Bryant</name></author><author><name sortKey="Schultz, N" uniqKey="Schultz N">N. Schultz</name></author><author><name sortKey="Thomas, H D" uniqKey="Thomas H">H.D. Thomas</name></author><author><name sortKey="Parker, K M" uniqKey="Parker K">K.M. Parker</name></author><author><name sortKey="Flower, D" uniqKey="Flower D">D. Flower</name></author><author><name sortKey="Lopez, E" uniqKey="Lopez E">E. Lopez</name></author><author><name sortKey="Kyle, S" uniqKey="Kyle S">S. Kyle</name></author><author><name sortKey="Meuth, M" uniqKey="Meuth M">M. Meuth</name></author><author><name sortKey="Curtin, N J" uniqKey="Curtin N">N.J. Curtin</name></author><author><name sortKey="Helleday, T" uniqKey="Helleday T">T. Helleday</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Myant, K" uniqKey="Myant K">K. Myant</name></author><author><name sortKey="Termanis, A" uniqKey="Termanis A">A. Termanis</name></author><author><name sortKey="Sundaram, A Y M" uniqKey="Sundaram A">A.Y.M. Sundaram</name></author><author><name sortKey="Boe, T" uniqKey="Boe T">T. Boe</name></author><author><name sortKey="Li, C" uniqKey="Li C">C. Li</name></author><author><name sortKey="Merusi, C" uniqKey="Merusi C">C. Merusi</name></author><author><name sortKey="Burrage, J" uniqKey="Burrage J">J. Burrage</name></author><author><name sortKey="De Las Heras, J I" uniqKey="De Las Heras J">J.I. de Las Heras</name></author><author><name sortKey="Stancheva, I" uniqKey="Stancheva I">I. Stancheva</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Samuelsson, J" uniqKey="Samuelsson J">J. Samuelsson</name></author><author><name sortKey="Dumbovic, G" uniqKey="Dumbovic G">G. Dumbovic</name></author><author><name sortKey="Polo, C" uniqKey="Polo C">C. Polo</name></author><author><name sortKey="Moreta, C" uniqKey="Moreta C">C. Moreta</name></author><author><name sortKey="Alibes, A" uniqKey="Alibes A">A. Alibés</name></author><author><name sortKey="Ruiz Larroya, T" uniqKey="Ruiz Larroya T">T. Ruiz-Larroya</name></author><author><name sortKey="Gimenez Bonafe, P" uniqKey="Gimenez Bonafe P">P. Giménez-Bonafé</name></author><author><name sortKey="Alonso, S" uniqKey="Alonso S">S. Alonso</name></author><author><name sortKey="Forcales, S V" uniqKey="Forcales S">S.-V. Forcales</name></author><author><name sortKey="Perucho, M" uniqKey="Perucho M">M. Perucho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, W" uniqKey="Yu W">W. Yu</name></author><author><name sortKey="Mcintosh, C" uniqKey="Mcintosh C">C. McIntosh</name></author><author><name sortKey="Lister, R" uniqKey="Lister R">R. Lister</name></author><author><name sortKey="Zhu, I" uniqKey="Zhu I">I. Zhu</name></author><author><name sortKey="Han, Y" uniqKey="Han Y">Y. Han</name></author><author><name sortKey="Ren, J" uniqKey="Ren J">J. Ren</name></author><author><name sortKey="Landsman, D" uniqKey="Landsman D">D. Landsman</name></author><author><name sortKey="Lee, E" uniqKey="Lee E">E. Lee</name></author><author><name sortKey="Briones, V" uniqKey="Briones V">V. Briones</name></author><author><name sortKey="Terashima, M" uniqKey="Terashima M">M. Terashima</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suzuki, T" uniqKey="Suzuki T">T. Suzuki</name></author><author><name sortKey="Farrar, J E" uniqKey="Farrar J">J.E. Farrar</name></author><author><name sortKey="Yegnasubramanian, S" uniqKey="Yegnasubramanian S">S. Yegnasubramanian</name></author><author><name sortKey="Zahed, M" uniqKey="Zahed M">M. Zahed</name></author><author><name sortKey="Suzuki, N" uniqKey="Suzuki N">N. Suzuki</name></author><author><name sortKey="Arceci, R J" uniqKey="Arceci R">R.J. Arceci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ren, J" uniqKey="Ren J">J. Ren</name></author><author><name sortKey="Finney, R" uniqKey="Finney R">R. Finney</name></author><author><name sortKey="Ni, K" uniqKey="Ni K">K. Ni</name></author><author><name sortKey="Cam, M" uniqKey="Cam M">M. Cam</name></author><author><name sortKey="Muegge, K" uniqKey="Muegge K">K. Muegge</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Weinstock, D M" uniqKey="Weinstock D">D.M. Weinstock</name></author><author><name sortKey="Nakanishi, K" uniqKey="Nakanishi K">K. Nakanishi</name></author><author><name sortKey="Helgadottir, H R" uniqKey="Helgadottir H">H.R. Helgadottir</name></author><author><name sortKey="Jasin, M" uniqKey="Jasin M">M. Jasin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nakanishi, K" uniqKey="Nakanishi K">K. Nakanishi</name></author><author><name sortKey="Cavallo, F" uniqKey="Cavallo F">F. Cavallo</name></author><author><name sortKey="Brunet, E" uniqKey="Brunet E">E. Brunet</name></author><author><name sortKey="Jasin, M" uniqKey="Jasin M">M. Jasin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Murr, R" uniqKey="Murr R">R. Murr</name></author><author><name sortKey="Loizou, J I" uniqKey="Loizou J">J.I. Loizou</name></author><author><name sortKey="Yang, Y G" uniqKey="Yang Y">Y.G. Yang</name></author><author><name sortKey="Cuenin, C" uniqKey="Cuenin C">C. Cuenin</name></author><author><name sortKey="Li, H" uniqKey="Li H">H. Li</name></author><author><name sortKey="Wang, Z Q" uniqKey="Wang Z">Z.Q. Wang</name></author><author><name sortKey="Herceg, Z" uniqKey="Herceg Z">Z. Herceg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nakamura, K" uniqKey="Nakamura K">K. Nakamura</name></author><author><name sortKey="Kato, A" uniqKey="Kato A">A. Kato</name></author><author><name sortKey="Kobayashi, J" uniqKey="Kobayashi J">J. Kobayashi</name></author><author><name sortKey="Yanagihara, H" uniqKey="Yanagihara H">H. Yanagihara</name></author><author><name sortKey="Sakamoto, S" uniqKey="Sakamoto S">S. Sakamoto</name></author><author><name sortKey="Oliveira, D V N P" uniqKey="Oliveira D">D.V.N.P. Oliveira</name></author><author><name sortKey="Shimada, M" uniqKey="Shimada M">M. Shimada</name></author><author><name sortKey="Tauchi, H" uniqKey="Tauchi H">H. Tauchi</name></author><author><name sortKey="Suzuki, H" uniqKey="Suzuki H">H. Suzuki</name></author><author><name sortKey="Tashiro, S" uniqKey="Tashiro S">S. Tashiro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Costelloe, T" uniqKey="Costelloe T">T. Costelloe</name></author><author><name sortKey="Louge, R" uniqKey="Louge R">R. Louge</name></author><author><name sortKey="Tomimatsu, N" uniqKey="Tomimatsu N">N. Tomimatsu</name></author><author><name sortKey="Mukherjee, B" uniqKey="Mukherjee B">B. Mukherjee</name></author><author><name sortKey="Martini, E" uniqKey="Martini E">E. Martini</name></author><author><name sortKey="Khadaroo, B" uniqKey="Khadaroo B">B. Khadaroo</name></author><author><name sortKey="Dubois, K" uniqKey="Dubois K">K. Dubois</name></author><author><name sortKey="Wiegant, W W" uniqKey="Wiegant W">W.W. Wiegant</name></author><author><name sortKey="Thierry, A" uniqKey="Thierry A">A. Thierry</name></author><author><name sortKey="Burma, S" uniqKey="Burma S">S. Burma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ziv, Y" uniqKey="Ziv Y">Y. Ziv</name></author><author><name sortKey="Bielopolski, D" uniqKey="Bielopolski D">D. Bielopolski</name></author><author><name sortKey="Galanty, Y" uniqKey="Galanty Y">Y. Galanty</name></author><author><name sortKey="Lukas, C" uniqKey="Lukas C">C. Lukas</name></author><author><name sortKey="Taya, Y" uniqKey="Taya Y">Y. Taya</name></author><author><name sortKey="Schultz, D C" uniqKey="Schultz D">D.C. Schultz</name></author><author><name sortKey="Lukas, J" uniqKey="Lukas J">J. Lukas</name></author><author><name sortKey="Bekker Jensen, S" uniqKey="Bekker Jensen S">S. Bekker-Jensen</name></author><author><name sortKey="Bartek, J" uniqKey="Bartek J">J. Bartek</name></author><author><name sortKey="Shiloh, Y" uniqKey="Shiloh Y">Y. Shiloh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Geuting, V" uniqKey="Geuting V">V. Geuting</name></author><author><name sortKey="Reul, C" uniqKey="Reul C">C. Reul</name></author><author><name sortKey="Lobrich, M" uniqKey="Lobrich M">M. Löbrich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ren, J" uniqKey="Ren J">J. Ren</name></author><author><name sortKey="Briones, V" uniqKey="Briones V">V. Briones</name></author><author><name sortKey="Barbour, S" uniqKey="Barbour S">S. Barbour</name></author><author><name sortKey="Yu, W" uniqKey="Yu W">W. Yu</name></author><author><name sortKey="Han, Y" uniqKey="Han Y">Y. Han</name></author><author><name sortKey="Terashima, M" uniqKey="Terashima M">M. Terashima</name></author><author><name sortKey="Muegge, K" uniqKey="Muegge K">K. Muegge</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goodarzi, A A" uniqKey="Goodarzi A">A.A. Goodarzi</name></author><author><name sortKey="Noon, A T" uniqKey="Noon A">A.T. Noon</name></author><author><name sortKey="Jeggo, P A" uniqKey="Jeggo P">P.A. Jeggo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Noon, A T" uniqKey="Noon A">A.T. Noon</name></author><author><name sortKey="Shibata, A" uniqKey="Shibata A">A. Shibata</name></author><author><name sortKey="Rief, N" uniqKey="Rief N">N. Rief</name></author><author><name sortKey="Lobrich, M" uniqKey="Lobrich M">M. Lobrich</name></author><author><name sortKey="Stewart, G S" uniqKey="Stewart G">G.S. Stewart</name></author><author><name sortKey="Jeggo, P A" uniqKey="Jeggo P">P.A. Jeggo</name></author><author><name sortKey="Goodarzi, A A" uniqKey="Goodarzi A">A.A. Goodarzi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Adkins, N L" uniqKey="Adkins N">N.L. Adkins</name></author><author><name sortKey="Niu, H" uniqKey="Niu H">H. Niu</name></author><author><name sortKey="Sung, P" uniqKey="Sung P">P. Sung</name></author><author><name sortKey="Peterson, C L" uniqKey="Peterson C">C.L. Peterson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Densham, R M" uniqKey="Densham R">R.M. Densham</name></author><author><name sortKey="Garvin, A J" uniqKey="Garvin A">A.J. Garvin</name></author><author><name sortKey="Stone, H R" uniqKey="Stone H">H.R. Stone</name></author><author><name sortKey="Strachan, J" uniqKey="Strachan J">J. Strachan</name></author><author><name sortKey="Baldock, R A" uniqKey="Baldock R">R.A. Baldock</name></author><author><name sortKey="Daza Martin, M" uniqKey="Daza Martin M">M. Daza-Martin</name></author><author><name sortKey="Fletcher, A" uniqKey="Fletcher A">A. Fletcher</name></author><author><name sortKey="Blair Reid, S" uniqKey="Blair Reid S">S. Blair-Reid</name></author><author><name sortKey="Beesley, J" uniqKey="Beesley J">J. Beesley</name></author><author><name sortKey="Johal, B" uniqKey="Johal B">B. Johal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mukherjee, B" uniqKey="Mukherjee B">B. Mukherjee</name></author><author><name sortKey="Tomimatsu, N" uniqKey="Tomimatsu N">N. Tomimatsu</name></author><author><name sortKey="Burma, S" uniqKey="Burma S">S. Burma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Costelloe, T" uniqKey="Costelloe T">T. Costelloe</name></author><author><name sortKey="Fitzgerald, J" uniqKey="Fitzgerald J">J. Fitzgerald</name></author><author><name sortKey="Murphy, N J" uniqKey="Murphy N">N.J. Murphy</name></author><author><name sortKey="Flaus, A" uniqKey="Flaus A">A. Flaus</name></author><author><name sortKey="Lowndes, N F" uniqKey="Lowndes N">N.F. Lowndes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yasuhara, T" uniqKey="Yasuhara T">T. Yasuhara</name></author><author><name sortKey="Kato, R" uniqKey="Kato R">R. Kato</name></author><author><name sortKey="Hagiwara, Y" uniqKey="Hagiwara Y">Y. Hagiwara</name></author><author><name sortKey="Shiotani, B" uniqKey="Shiotani B">B. Shiotani</name></author><author><name sortKey="Yamauchi, M" uniqKey="Yamauchi M">M. Yamauchi</name></author><author><name sortKey="Nakada, S" uniqKey="Nakada S">S. Nakada</name></author><author><name sortKey="Shibata, A" uniqKey="Shibata A">A. Shibata</name></author><author><name sortKey="Miyagawa, K" uniqKey="Miyagawa K">K. Miyagawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aymard, F" uniqKey="Aymard F">F. Aymard</name></author><author><name sortKey="Bugler, B" uniqKey="Bugler B">B. Bugler</name></author><author><name sortKey="Schmidt, C K" uniqKey="Schmidt C">C.K. Schmidt</name></author><author><name sortKey="Guillou, E" uniqKey="Guillou E">E. Guillou</name></author><author><name sortKey="Caron, P" uniqKey="Caron P">P. Caron</name></author><author><name sortKey="Briois, S" uniqKey="Briois S">S. Briois</name></author><author><name sortKey="Iacovoni, J S" uniqKey="Iacovoni J">J.S. Iacovoni</name></author><author><name sortKey="Daburon, V" uniqKey="Daburon V">V. Daburon</name></author><author><name sortKey="Miller, K M" uniqKey="Miller K">K.M. Miller</name></author><author><name sortKey="Jackson, S P" uniqKey="Jackson S">S.P. Jackson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kakarougkas, A" uniqKey="Kakarougkas A">A. Kakarougkas</name></author><author><name sortKey="Ismail, A" uniqKey="Ismail A">A. Ismail</name></author><author><name sortKey="Klement, K" uniqKey="Klement K">K. Klement</name></author><author><name sortKey="Goodarzi, A A" uniqKey="Goodarzi A">A.A. Goodarzi</name></author><author><name sortKey="Conrad, S" uniqKey="Conrad S">S. Conrad</name></author><author><name sortKey="Freire, R" uniqKey="Freire R">R. Freire</name></author><author><name sortKey="Shibata, A" uniqKey="Shibata A">A. Shibata</name></author><author><name sortKey="Lobrich, M" uniqKey="Lobrich M">M. Lobrich</name></author><author><name sortKey="Jeggo, P A" uniqKey="Jeggo P">P.A. Jeggo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bajrami, I" uniqKey="Bajrami I">I. Bajrami</name></author><author><name sortKey="Frankum, J R" uniqKey="Frankum J">J.R. Frankum</name></author><author><name sortKey="Konde, A" uniqKey="Konde A">A. Konde</name></author><author><name sortKey="Miller, R E" uniqKey="Miller R">R.E. Miller</name></author><author><name sortKey="Rehman, F L" uniqKey="Rehman F">F.L. Rehman</name></author><author><name sortKey="Brough, R" uniqKey="Brough R">R. Brough</name></author><author><name sortKey="Campbell, J" uniqKey="Campbell J">J. Campbell</name></author><author><name sortKey="Sims, D" uniqKey="Sims D">D. Sims</name></author><author><name sortKey="Rafiq, R" uniqKey="Rafiq R">R. Rafiq</name></author><author><name sortKey="Hooper, S" uniqKey="Hooper S">S. Hooper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hassan, S" uniqKey="Hassan S">S. Hassan</name></author><author><name sortKey="Esch, A" uniqKey="Esch A">A. Esch</name></author><author><name sortKey="Liby, T" uniqKey="Liby T">T. Liby</name></author><author><name sortKey="Gray, J W" uniqKey="Gray J">J.W. Gray</name></author><author><name sortKey="Heiser, L M" uniqKey="Heiser L">L.M. Heiser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alagoz, M" uniqKey="Alagoz M">M. Alagoz</name></author><author><name sortKey="Katsuki, Y" uniqKey="Katsuki Y">Y. Katsuki</name></author><author><name sortKey="Ogiwara, H" uniqKey="Ogiwara H">H. Ogiwara</name></author><author><name sortKey="Ogi, T" uniqKey="Ogi T">T. Ogi</name></author><author><name sortKey="Shibata, A" uniqKey="Shibata A">A. Shibata</name></author><author><name sortKey="Kakarougkas, A" uniqKey="Kakarougkas A">A. Kakarougkas</name></author><author><name sortKey="Jeggo, P" uniqKey="Jeggo P">P. Jeggo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tsouroula, K" uniqKey="Tsouroula K">K. Tsouroula</name></author><author><name sortKey="Furst, A" uniqKey="Furst A">A. Furst</name></author><author><name sortKey="Rogier, M" uniqKey="Rogier M">M. Rogier</name></author><author><name sortKey="Heyer, V" uniqKey="Heyer V">V. Heyer</name></author><author><name sortKey="Maglott Roth, A" uniqKey="Maglott Roth A">A. Maglott-Roth</name></author><author><name sortKey="Ferrand, A" uniqKey="Ferrand A">A. Ferrand</name></author><author><name sortKey="Reina San Martin, B" uniqKey="Reina San Martin B">B. Reina-San-Martin</name></author><author><name sortKey="Soutoglou, E" uniqKey="Soutoglou E">E. Soutoglou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shibata, A" uniqKey="Shibata A">A. Shibata</name></author><author><name sortKey="Steinlage, M" uniqKey="Steinlage M">M. Steinlage</name></author><author><name sortKey="Barton, O" uniqKey="Barton O">O. Barton</name></author><author><name sortKey="Juhasz, S" uniqKey="Juhasz S">S. Juhász</name></author><author><name sortKey="Kunzel, J" uniqKey="Kunzel J">J. Künzel</name></author><author><name sortKey="Spies, J" uniqKey="Spies J">J. Spies</name></author><author><name sortKey="Shibata, A" uniqKey="Shibata A">A. Shibata</name></author><author><name sortKey="Jeggo, P A" uniqKey="Jeggo P">P.A. Jeggo</name></author><author><name sortKey="Lobrich, M" uniqKey="Lobrich M">M. Löbrich</name></author><author><name sortKey="Biehs, R" uniqKey="Biehs R">R. Biehs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Unoki, M" uniqKey="Unoki M">M. Unoki</name></author><author><name sortKey="Funabiki, H" uniqKey="Funabiki H">H. Funabiki</name></author><author><name sortKey="Velasco, G" uniqKey="Velasco G">G. Velasco</name></author><author><name sortKey="Francastel, C" uniqKey="Francastel C">C. Francastel</name></author><author><name sortKey="Sasaki, H" uniqKey="Sasaki H">H. Sasaki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brunton, H" uniqKey="Brunton H">H. Brunton</name></author><author><name sortKey="Goodarzi, A A" uniqKey="Goodarzi A">A.A. Goodarzi</name></author><author><name sortKey="Noon, A T" uniqKey="Noon A">A.T. Noon</name></author><author><name sortKey="Shrikhande, A" uniqKey="Shrikhande A">A. Shrikhande</name></author><author><name sortKey="Hansen, R S" uniqKey="Hansen R">R.S. Hansen</name></author><author><name sortKey="Jeggo, P A" uniqKey="Jeggo P">P.A. Jeggo</name></author><author><name sortKey="Shibata, A" uniqKey="Shibata A">A. Shibata</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jin, B" uniqKey="Jin B">B. Jin</name></author><author><name sortKey="Tao, Q" uniqKey="Tao Q">Q. Tao</name></author><author><name sortKey="Peng, J" uniqKey="Peng J">J. Peng</name></author><author><name sortKey="Soo, H M" uniqKey="Soo H">H.M. Soo</name></author><author><name sortKey="Wu, W" uniqKey="Wu W">W. Wu</name></author><author><name sortKey="Ying, J" uniqKey="Ying J">J. Ying</name></author><author><name sortKey="Fields, C R" uniqKey="Fields C">C.R. Fields</name></author><author><name sortKey="Delmas, A I L" uniqKey="Delmas A">A.I.L. Delmas</name></author><author><name sortKey="Liu, X" uniqKey="Liu X">X. Liu</name></author><author><name sortKey="Qiu, J" uniqKey="Qiu J">J. Qiu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hansen, R S" uniqKey="Hansen R">R.S. Hansen</name></author><author><name sortKey="Wijmenga, C" uniqKey="Wijmenga C">C. Wijmenga</name></author><author><name sortKey="Luo, P" uniqKey="Luo P">P. Luo</name></author><author><name sortKey="Stanek, A M" uniqKey="Stanek A">A.M. Stanek</name></author><author><name sortKey="Canfield, T K" uniqKey="Canfield T">T.K. Canfield</name></author><author><name sortKey="Weemaes, C M R" uniqKey="Weemaes C">C.M.R. Weemaes</name></author><author><name sortKey="Gartler, S M" uniqKey="Gartler S">S.M. Gartler</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Chambers, Anna L" sort="Chambers, Anna L" uniqKey="Chambers A" first="Anna L" last="Chambers">Anna L. Chambers</name><name sortKey="Kollarovi, Gabriel" sort="Kollarovi, Gabriel" uniqKey="Kollarovi G" first="Gabriel" last="Kollárovi">Gabriel Kollárovi</name><name sortKey="Shaw, Edward P" sort="Shaw, Edward P" uniqKey="Shaw E" first="Edward P" last="Shaw">Edward P. Shaw</name><name sortKey="Topping, Caitriona E" sort="Topping, Caitriona E" uniqKey="Topping C" first="Caitríona E" last="Topping">Caitríona E. Topping</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000346 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000346 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:7038987
|texte= The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination and contributes to DSB repair within heterochromatin
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:31802118" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ChloroquineV1
| This area was generated with Dilib version V0.6.33. |  |