Interstitial granulomatous dermatitis: a misdiagnosed cutaneous form of systemic lupus erythematosus?
Identifieur interne : 001989 ( Main/Curation ); précédent : 001988; suivant : 001990Interstitial granulomatous dermatitis: a misdiagnosed cutaneous form of systemic lupus erythematosus?
Auteurs : S. Blaise ; D. Salameire [France] ; P. H. CarpentierSource :
- Clinical and Experimental Dermatology [ 0307-6938 ] ; 2008-11.
English descriptors
- Teeft :
- Acad, Acad dermatol, Adverse event, Aetiology, Antiphospholipid, Antiphospholipid syndrome, Atypical, Autoimmune, Autoimmune diseases, Blaise, British association, Clinical presentation, Cutaneous, Cutaneous lesions, Dermatitis, Dermatol, Dermatology, Erythematous, Experimental dermatology, Focal collagen necrosis, Granulomatous, Granulomatous dermatitis, Grenoble, Grenoble university hospital, Histological, Histological features, Immunological features, Interstitial, Interstitial granulomatous dermatitis, Journal compilation, Lupus, Macular eruption, Misdiagnosed, Misdiagnosed cutaneous form, Neutrophilic, Palisaded, Palisaded histiocytic granuloma, Palisaded neutrophilic, Primary antiphospholipid syndrome, Reticular, Rheumatoid, Rheumatoid factor, Systemic lupus erythematosus, Vascular medicine, Violaceous centre.
Abstract
Interstitial granulomatous dermatitis (IGD) is a recently described, rare dermatological entity. The clinical features are diverse and the precise aetiology is unknown. We present a rare and atypical case of IGD in a patient with systemic lupus erythematosus (SLE). A 26‐year‐old woman had been diagnosed with SLE when she was 15 years old. The diagnosis was based on cutaneous, articular, pulmonary, haematological and immunological features. The patient presented with a cutaneous diffuse macular eruption on the limbs, appearing in a cockade (rosette) pattern with a violaceous centre and erythematous surround. The face and trunk were spared. The cutaneous histological features led us to consider a diagnosis of IGD. The lesions disappeared after 15 days of systemic steroid therapy. This case is a new clinical form of IGD with an atypical location and clinical presentation. IGD has usually been associated with drug‐related adverse reactions and autoimmune diseases. Reports in the literature of IGD in patients with SLE are rare.
Url:
DOI: 10.1111/j.1365-2230.2008.02774.x
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<front><div type="abstract" xml:lang="en">Interstitial granulomatous dermatitis (IGD) is a recently described, rare dermatological entity. The clinical features are diverse and the precise aetiology is unknown. We present a rare and atypical case of IGD in a patient with systemic lupus erythematosus (SLE). A 26‐year‐old woman had been diagnosed with SLE when she was 15 years old. The diagnosis was based on cutaneous, articular, pulmonary, haematological and immunological features. The patient presented with a cutaneous diffuse macular eruption on the limbs, appearing in a cockade (rosette) pattern with a violaceous centre and erythematous surround. The face and trunk were spared. The cutaneous histological features led us to consider a diagnosis of IGD. The lesions disappeared after 15 days of systemic steroid therapy. This case is a new clinical form of IGD with an atypical location and clinical presentation. IGD has usually been associated with drug‐related adverse reactions and autoimmune diseases. Reports in the literature of IGD in patients with SLE are rare.</div>
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