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Interstitial granulomatous dermatitis: a misdiagnosed cutaneous form of systemic lupus erythematosus?

Identifieur interne : 002236 ( Istex/Corpus ); précédent : 002235; suivant : 002237

Interstitial granulomatous dermatitis: a misdiagnosed cutaneous form of systemic lupus erythematosus?

Auteurs : S. Blaise ; D. Salameire ; P. H. Carpentier

Source :

RBID : ISTEX:B69BB28B046EBCDBD2F679BF23D72F9AD99B6DF6

English descriptors

Abstract

Interstitial granulomatous dermatitis (IGD) is a recently described, rare dermatological entity. The clinical features are diverse and the precise aetiology is unknown. We present a rare and atypical case of IGD in a patient with systemic lupus erythematosus (SLE). A 26‐year‐old woman had been diagnosed with SLE when she was 15 years old. The diagnosis was based on cutaneous, articular, pulmonary, haematological and immunological features. The patient presented with a cutaneous diffuse macular eruption on the limbs, appearing in a cockade (rosette) pattern with a violaceous centre and erythematous surround. The face and trunk were spared. The cutaneous histological features led us to consider a diagnosis of IGD. The lesions disappeared after 15 days of systemic steroid therapy. This case is a new clinical form of IGD with an atypical location and clinical presentation. IGD has usually been associated with drug‐related adverse reactions and autoimmune diseases. Reports in the literature of IGD in patients with SLE are rare.

Url:
DOI: 10.1111/j.1365-2230.2008.02774.x

Links to Exploration step

ISTEX:B69BB28B046EBCDBD2F679BF23D72F9AD99B6DF6

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<correspondenceTo>Dr S. Blaise, Department of Vascular Medicine, Grenoble University Hospital, BP 217, 38043 Grenoble, cedex 09, France.
E‐mail:
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<title type="main">Interstitial granulomatous dermatitis: a misdiagnosed cutaneous form of systemic lupus erythematosus?</title>
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<i>S. Blaise</i>
et al.</title>
<title type="short">Interstitial granulomatous dermatitis: a misdiagnosed cutaneous form of SLE?</title>
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<p>Interstitial granulomatous dermatitis (IGD) is a recently described, rare dermatological entity. The clinical features are diverse and the precise aetiology is unknown. We present a rare and atypical case of IGD in a patient with systemic lupus erythematosus (SLE). A 26‐year‐old woman had been diagnosed with SLE when she was 15 years old. The diagnosis was based on cutaneous, articular, pulmonary, haematological and immunological features. The patient presented with a cutaneous diffuse macular eruption on the limbs, appearing in a cockade (rosette) pattern with a violaceous centre and erythematous surround. The face and trunk were spared. The cutaneous histological features led us to consider a diagnosis of IGD. The lesions disappeared after 15 days of systemic steroid therapy. This case is a new clinical form of IGD with an atypical location and clinical presentation. IGD has usually been associated with drug‐related adverse reactions and autoimmune diseases. Reports in the literature of IGD in patients with SLE are rare.</p>
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<p>Conflict of interest: none declared.</p>
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<abstract lang="en">Interstitial granulomatous dermatitis (IGD) is a recently described, rare dermatological entity. The clinical features are diverse and the precise aetiology is unknown. We present a rare and atypical case of IGD in a patient with systemic lupus erythematosus (SLE). A 26‐year‐old woman had been diagnosed with SLE when she was 15 years old. The diagnosis was based on cutaneous, articular, pulmonary, haematological and immunological features. The patient presented with a cutaneous diffuse macular eruption on the limbs, appearing in a cockade (rosette) pattern with a violaceous centre and erythematous surround. The face and trunk were spared. The cutaneous histological features led us to consider a diagnosis of IGD. The lesions disappeared after 15 days of systemic steroid therapy. This case is a new clinical form of IGD with an atypical location and clinical presentation. IGD has usually been associated with drug‐related adverse reactions and autoimmune diseases. Reports in the literature of IGD in patients with SLE are rare.</abstract>
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