Idiopathic pulmonary hemosiderosis complicated by Down syndrome
Identifieur interne : 001913 ( Istex/Curation ); précédent : 001912; suivant : 001914Idiopathic pulmonary hemosiderosis complicated by Down syndrome
Auteurs : Hirofumi Watanabe [Japon] ; Mamoru Ayusawa [Japon] ; Masataka Kato [Japon] ; Ami Chou [Japon] ; Akiko Komori [Japon] ; Yuriko Abe [Japon] ; Masaharu Matsumura [Japon] ; Hiroshi Kamiyama [Japon] ; Hiroyuki Izumi [Japon] ; Shori Takahashi [Japon]Source :
- Pediatrics International [ 1328-8067 ] ; 2015-10.
Abstract
We report the case of a 9‐year‐old girl with Down syndrome (DS) diagnosed with idiopathic pulmonary hemosiderosis (IPH). Although acute pneumonia complicated by hemolytic anemia was suspected, IPH was finally diagnosed on bronchoscopy. Treatment with prednisolone achieved good clinical response. An association between IPH and DS was not able to be identified, but immunological issues in DS may contribute to the onset of IPH. Recurrent and intractable respiratory symptoms with marked infiltrative shadows in the bilateral lungs and complicated by severe anemia in patients with DS should suggest IPH.
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DOI: 10.1111/ped.12690
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pulmonary hemosiderosis complicated by Down syndrome</title><author><name sortKey="Watanabe, Hirofumi" sort="Watanabe, Hirofumi" uniqKey="Watanabe H" first="Hirofumi" last="Watanabe">Hirofumi Watanabe</name><affiliation wicri:level="1"><mods:affiliation>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan</mods:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>E-mail: mehi11016@g.nihon‐u.ac.jp</mods:affiliation><country wicri:rule="url">Japon</country></affiliation></author><author><name sortKey="Ayusawa, Mamoru" sort="Ayusawa, Mamoru" uniqKey="Ayusawa M" first="Mamoru" last="Ayusawa">Mamoru Ayusawa</name><affiliation wicri:level="1"><mods:affiliation>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan</mods:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo</wicri:regionArea></affiliation></author><author><name sortKey="Kato, Masataka" sort="Kato, Masataka" uniqKey="Kato M" first="Masataka" last="Kato">Masataka Kato</name><affiliation wicri:level="1"><mods:affiliation>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan</mods:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo</wicri:regionArea></affiliation></author><author><name sortKey="Chou, Ami" sort="Chou, Ami" uniqKey="Chou A" first="Ami" last="Chou">Ami Chou</name><affiliation wicri:level="1"><mods:affiliation>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan</mods:affiliation><country 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Child Health, Nihon University School of Medicine, Tokyo</wicri:regionArea></affiliation></author><author><name sortKey="Matsumura, Masaharu" sort="Matsumura, Masaharu" uniqKey="Matsumura M" first="Masaharu" last="Matsumura">Masaharu Matsumura</name><affiliation wicri:level="1"><mods:affiliation>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan</mods:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo</wicri:regionArea></affiliation></author><author><name sortKey="Kamiyama, Hiroshi" sort="Kamiyama, Hiroshi" uniqKey="Kamiyama H" first="Hiroshi" last="Kamiyama">Hiroshi Kamiyama</name><affiliation wicri:level="1"><mods:affiliation>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan</mods:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo</wicri:regionArea></affiliation></author><author><name sortKey="Izumi, Hiroyuki" sort="Izumi, Hiroyuki" uniqKey="Izumi H" first="Hiroyuki" last="Izumi">Hiroyuki Izumi</name><affiliation wicri:level="1"><mods:affiliation>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan</mods:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Itabashi Medical Association Hospital, Tokyo, Itabashi, Japan</mods:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Itabashi Medical Association Hospital, Tokyo, Itabashi</wicri:regionArea></affiliation></author><author><name sortKey="Takahashi, Shori" sort="Takahashi, Shori" uniqKey="Takahashi S" first="Shori" last="Takahashi">Shori Takahashi</name><affiliation wicri:level="1"><mods:affiliation>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan</mods:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Pediatrics International</title><title level="j" type="alt">PEDIATRICS INTERNATIONAL</title><idno type="ISSN">1328-8067</idno><idno type="eISSN">1442-200X</idno><imprint><biblScope unit="vol">57</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="1009">1009</biblScope><biblScope unit="page" to="1012">1012</biblScope><biblScope unit="page-count">4</biblScope><date type="published" when="2015-10">2015-10</date></imprint><idno type="ISSN">1328-8067</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1328-8067</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">We report the case of a 9‐year‐old girl with Down syndrome (DS) diagnosed with idiopathic pulmonary hemosiderosis (IPH). Although acute pneumonia complicated by hemolytic anemia was suspected, IPH was finally diagnosed on bronchoscopy. Treatment with prednisolone achieved good clinical response. An association between IPH and DS was not able to be identified, but immunological issues in DS may contribute to the onset of IPH. Recurrent and intractable respiratory symptoms with marked infiltrative shadows in the bilateral lungs and complicated by severe anemia in patients with DS should suggest IPH.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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