Serveur d'exploration Hippolyte Bernheim

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The effect of physical restraint on IL-1β- and LPS-induced fever

Identifieur interne : 000A44 ( Main/Merge ); précédent : 000A43; suivant : 000A45

The effect of physical restraint on IL-1β- and LPS-induced fever

Auteurs : Nancy C. Long [Japon] ; Akio Morimoto [Japon] ; Tomoki Nakamori [Japon] ; Naotoshi Murakami [Japon]

Source :

RBID : ISTEX:38D9A0D238CE13F9ED9A07E26A442A56586EE885

English descriptors

Abstract

Abstract: The stress of physical restraint has been shown to cause an elevation in the body temperature of rats. In this study, we compared the febrile responses of restrained and unrestrained animals to the injection of interleukin-1β (IL-1β) and lipopolysaccharide (LPS). We found that, prior to injection, the body temperature of the restrained animals was about 1°C higher than that of the unrestrained rats. The restrained rats showed significantly smaller increases in body temperature in response to the injection of either pyrogen than did the unrestrained animals.

Url:
DOI: 10.1016/0031-9384(91)90556-4

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ISTEX:38D9A0D238CE13F9ED9A07E26A442A56586EE885

Le document en format XML

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<term>Physical restraint</term>
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