The effect of physical restraint on IL-1β- and LPS-induced fever
Identifieur interne : 000A44 ( Main/Merge ); précédent : 000A43; suivant : 000A45The effect of physical restraint on IL-1β- and LPS-induced fever
Auteurs : Nancy C. Long [Japon] ; Akio Morimoto [Japon] ; Tomoki Nakamori [Japon] ; Naotoshi Murakami [Japon]Source :
- Physiology & Behavior [ 0031-9384 ] ; 1991.
English descriptors
- Teeft :
- Antipyretic mechanisms, Body temperature, Body temperatures, Emotional hyperthermia, Febrile, Febrile response, Febrile responses, Hyperthermia, Intraperitoneal injection, Minutes postinjection, Other aspects, Peak change, Physical restraint, Physiol, Postinjection, Prostaglandin, Rain postinjection, Rat, Restraint period, Second peak, Separate groups, Single group, Sterile saline, Stress hyperthermia, Thermal biology, Unrestrained, Unrestrained animals, Unrestrained rats, Wistar rats.
Abstract
Abstract: The stress of physical restraint has been shown to cause an elevation in the body temperature of rats. In this study, we compared the febrile responses of restrained and unrestrained animals to the injection of interleukin-1β (IL-1β) and lipopolysaccharide (LPS). We found that, prior to injection, the body temperature of the restrained animals was about 1°C higher than that of the unrestrained rats. The restrained rats showed significantly smaller increases in body temperature in response to the injection of either pyrogen than did the unrestrained animals.
Url:
DOI: 10.1016/0031-9384(91)90556-4
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<term>Febrile</term>
<term>Febrile response</term>
<term>Febrile responses</term>
<term>Hyperthermia</term>
<term>Intraperitoneal injection</term>
<term>Minutes postinjection</term>
<term>Other aspects</term>
<term>Peak change</term>
<term>Physical restraint</term>
<term>Physiol</term>
<term>Postinjection</term>
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<term>Rain postinjection</term>
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<term>Second peak</term>
<term>Separate groups</term>
<term>Single group</term>
<term>Sterile saline</term>
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<term>Thermal biology</term>
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<front><div type="abstract" xml:lang="en">Abstract: The stress of physical restraint has been shown to cause an elevation in the body temperature of rats. In this study, we compared the febrile responses of restrained and unrestrained animals to the injection of interleukin-1β (IL-1β) and lipopolysaccharide (LPS). We found that, prior to injection, the body temperature of the restrained animals was about 1°C higher than that of the unrestrained rats. The restrained rats showed significantly smaller increases in body temperature in response to the injection of either pyrogen than did the unrestrained animals.</div>
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