Achieving eugastrinaemia in Zollinger-Ellison syndrome: resection or enucleation?
Identifieur interne : 000639 ( PubMed/Curation ); précédent : 000638; suivant : 000640Achieving eugastrinaemia in Zollinger-Ellison syndrome: resection or enucleation?
Auteurs : P A Thodiyil [Royaume-Uni] ; N S El-Masry ; R C WilliamsonSource :
- Digestive surgery [ 0253-4886 ] ; 2001.
English descriptors
- KwdEn :
- Adult, Aged, Angiography, Digital Subtraction, Fasting, Female, Gastrectomy (adverse effects), Gastrectomy (methods), Gastrins (blood), Gastroscopy, Humans, Male, Middle Aged, Neoplasm Recurrence, Local (mortality), Pancreatectomy (adverse effects), Pancreatectomy (methods), Pancreaticoduodenectomy (adverse effects), Pancreaticoduodenectomy (methods), Retrospective Studies, Tomography, X-Ray Computed, Treatment Outcome, Zollinger-Ellison Syndrome (blood), Zollinger-Ellison Syndrome (diagnosis), Zollinger-Ellison Syndrome (surgery).
- MESH :
- chemical , blood : Gastrins.
- adverse effects : Gastrectomy, Pancreatectomy, Pancreaticoduodenectomy.
- blood : Zollinger-Ellison Syndrome.
- diagnosis : Zollinger-Ellison Syndrome.
- methods : Gastrectomy, Pancreatectomy, Pancreaticoduodenectomy.
- mortality : Neoplasm Recurrence, Local.
- surgery : Zollinger-Ellison Syndrome.
- Adult, Aged, Angiography, Digital Subtraction, Fasting, Female, Gastroscopy, Humans, Male, Middle Aged, Retrospective Studies, Tomography, X-Ray Computed, Treatment Outcome.
Abstract
Eugastrinaemia in Zollinger-Ellison syndrome can be an elusive goal, nearly one third of laparotomies failing to detect the tumour.
DOI: 50111
PubMed: 11351156
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pubmed:11351156Le document en format XML
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type="pmid">11351156</idno><idno type="doi">50111</idno><idno type="wicri:Area/PubMed/Corpus">000639</idno><idno type="wicri:Area/PubMed/Curation">000639</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Achieving eugastrinaemia in Zollinger-Ellison syndrome: resection or enucleation?</title><author><name sortKey="Thodiyil, P A" sort="Thodiyil, P A" uniqKey="Thodiyil P" first="P A" last="Thodiyil">P A Thodiyil</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Hammersmith Hospital, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Surgery, Hammersmith Hospital, London</wicri:regionArea></affiliation></author><author><name sortKey="El Masry, N S" sort="El Masry, N S" uniqKey="El Masry N" first="N S" last="El-Masry">N S El-Masry</name></author><author><name sortKey="Williamson, R C" sort="Williamson, R C" uniqKey="Williamson R" first="R C" last="Williamson">R C Williamson</name></author></analytic><series><title level="j">Digestive surgery</title><idno type="ISSN">0253-4886</idno><imprint><date when="2001" type="published">2001</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Angiography, Digital Subtraction</term><term>Fasting</term><term>Female</term><term>Gastrectomy (adverse effects)</term><term>Gastrectomy (methods)</term><term>Gastrins (blood)</term><term>Gastroscopy</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neoplasm Recurrence, Local (mortality)</term><term>Pancreatectomy (adverse effects)</term><term>Pancreatectomy (methods)</term><term>Pancreaticoduodenectomy (adverse effects)</term><term>Pancreaticoduodenectomy (methods)</term><term>Retrospective Studies</term><term>Tomography, X-Ray Computed</term><term>Treatment Outcome</term><term>Zollinger-Ellison Syndrome (blood)</term><term>Zollinger-Ellison Syndrome (diagnosis)</term><term>Zollinger-Ellison Syndrome (surgery)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Gastrins</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Gastrectomy</term><term>Pancreatectomy</term><term>Pancreaticoduodenectomy</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Zollinger-Ellison Syndrome</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Zollinger-Ellison Syndrome</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Gastrectomy</term><term>Pancreatectomy</term><term>Pancreaticoduodenectomy</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Neoplasm Recurrence, Local</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Zollinger-Ellison Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Angiography, Digital Subtraction</term><term>Fasting</term><term>Female</term><term>Gastroscopy</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Tomography, X-Ray Computed</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Eugastrinaemia in Zollinger-Ellison syndrome can be an elusive goal, nearly one third of laparotomies failing to detect the tumour.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">11351156</PMID><DateCreated><Year>2001</Year><Month>05</Month><Day>14</Day></DateCreated><DateCompleted><Year>2001</Year><Month>07</Month><Day>26</Day></DateCompleted><DateRevised><Year>2004</Year><Month>11</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0253-4886</ISSN><JournalIssue CitedMedium="Print"><Volume>18</Volume><Issue>2</Issue><PubDate><Year>2001</Year></PubDate></JournalIssue><Title>Digestive surgery</Title><ISOAbbreviation>Dig Surg</ISOAbbreviation></Journal><ArticleTitle>Achieving eugastrinaemia in Zollinger-Ellison syndrome: resection or enucleation?</ArticleTitle><Pagination><MedlinePgn>118-23</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Eugastrinaemia in Zollinger-Ellison syndrome can be an elusive goal, nearly one third of laparotomies failing to detect the tumour.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A personal series of 13 patients with a mean age of 52 years operated between 1980 and 1996 was reviewed retrospectively. All patients had fasting hypergastrinaemia and recalcitrant ulcer disease with or without diarrhoea.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Computed tomography or selective visceral angiography localised the tumour to the pancreas in 6 of 12 elective patients; the thirteenth presented with a perforated duodenal ulcer. All underwent laparotomy with gastrinoma tissue being completely excised in every case, including the 6 patients with failed pre-operative localisation whose tumours arose from the duodenum (4), pancreas (1) and lymph node (1). Eugastrinaemia was achieved in all but 1 patient and was sustained during a mean follow-up of 5.2 years (SD = 4.2 years). These 12 patients remained clinically free of disease during a mean clinical follow-up of 7.5 years (SD = 5.0 years; range 2-19 years). There were no postoperative deaths, but 3 died from recurrent tumour at 3-7 years.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Since normalisation of serum gastrin was achieved in 12 of 13 patients, laparotomy may well be worthwhile even if the gastrinoma cannot be localised pre-opera- tively.</AbstractText><CopyrightInformation>Copyright 2001 S. Karger AG, Basel</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Thodiyil</LastName><ForeName>P A</ForeName><Initials>PA</Initials><AffiliationInfo><Affiliation>Department of Surgery, Hammersmith Hospital, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>El-Masry</LastName><ForeName>N S</ForeName><Initials>NS</Initials></Author><Author ValidYN="Y"><LastName>Williamson</LastName><ForeName>R C</ForeName><Initials>RC</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Dig Surg</MedlineTA><NlmUniqueID>8501808</NlmUniqueID><ISSNLinking>0253-4886</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005755">Gastrins</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D015901">Angiography, Digital Subtraction</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005215">Fasting</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005743">Gastrectomy</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005755">Gastrins</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000097">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005773">Gastroscopy</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009364">Neoplasm Recurrence, Local</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000401">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010180">Pancreatectomy</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016577">Pancreaticoduodenectomy</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012189">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014057">Tomography, X-Ray Computed</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016896">Treatment Outcome</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D015043">Zollinger-Ellison Syndrome</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000097">blood</QualifierName><QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000601">surgery</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2001</Year><Month>5</Month><Day>15</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2001</Year><Month>7</Month><Day>28</Day><Hour>10</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2001</Year><Month>5</Month><Day>15</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">11351156</ArticleId><ArticleId IdType="pii">50111</ArticleId><ArticleId IdType="doi">50111</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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