Lipaemia: an overrated interference?
Identifieur interne : 000576 ( PubMed/Corpus ); précédent : 000575; suivant : 000577Lipaemia: an overrated interference?
Auteurs : N R Anderson ; S. Slim ; R. Gama ; M R HollandSource :
- British journal of biomedical science [ 0967-4845 ] ; 2003.
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Lipids.
- methods : Blood Chemical Analysis.
- Artifacts, Chemical Precipitation, Humans, Polymers.
Abstract
Reagent method sheets for analysis of common serum analytes often highlight the possibility of interference from lipaemia but the information given is often brief and may not be instrument-specific. Thus study assesses the degree of interference from lipaemia in a range of common serum analytes on the Bayer Opera (with a serum blank) using a commercial polymer, LipoClear, as a lipid-clearing agent. Serum samples (mean serum triglyceride 6.89 [range 0.58-28.4] mmol/L) are analysed for 14 common chemistry analytes and the results compared before and after treatment with LipoClear. Results showed no significant critical differences in analyte values before and after treatment, except for an expected fall in total protein, phosphate, cholesterol and triglyceride concentrations. Most of the common analytes in use on the Bayer Opera are not subject to interference from lipaemia; however, we recommend that where method sheets indicate interference from lipaemia then this should be quantified for the analyte in question.
PubMed: 14560789
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Gama</name></author><author><name sortKey="Holland, M R" sort="Holland, M R" uniqKey="Holland M" first="M R" last="Holland">M R Holland</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2003">2003</date><idno type="RBID">pubmed:14560789</idno><idno type="pmid">14560789</idno><idno type="wicri:Area/PubMed/Corpus">000576</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Lipaemia: an overrated interference?</title><author><name sortKey="Anderson, N R" sort="Anderson, N R" uniqKey="Anderson N" first="N R" last="Anderson">N R Anderson</name><affiliation><nlm:affiliation>Department of Clinical Chemistry, New Cross Hospital, Wolverhampton WV10 OQP, UK. neil.anderson@rwh-tr.nhs.uk</nlm:affiliation></affiliation></author><author><name sortKey="Slim, S" sort="Slim, S" uniqKey="Slim S" first="S" last="Slim">S. Slim</name></author><author><name sortKey="Gama, R" sort="Gama, R" uniqKey="Gama R" first="R" last="Gama">R. Gama</name></author><author><name sortKey="Holland, M R" sort="Holland, M R" uniqKey="Holland M" first="M R" last="Holland">M R Holland</name></author></analytic><series><title level="j">British journal of biomedical science</title><idno type="ISSN">0967-4845</idno><imprint><date when="2003" type="published">2003</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Artifacts</term><term>Blood Chemical Analysis (methods)</term><term>Chemical Precipitation</term><term>Humans</term><term>Lipids (blood)</term><term>Polymers</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Lipids</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Blood Chemical Analysis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Artifacts</term><term>Chemical Precipitation</term><term>Humans</term><term>Polymers</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Reagent method sheets for analysis of common serum analytes often highlight the possibility of interference from lipaemia but the information given is often brief and may not be instrument-specific. Thus study assesses the degree of interference from lipaemia in a range of common serum analytes on the Bayer Opera (with a serum blank) using a commercial polymer, LipoClear, as a lipid-clearing agent. Serum samples (mean serum triglyceride 6.89 [range 0.58-28.4] mmol/L) are analysed for 14 common chemistry analytes and the results compared before and after treatment with LipoClear. Results showed no significant critical differences in analyte values before and after treatment, except for an expected fall in total protein, phosphate, cholesterol and triglyceride concentrations. Most of the common analytes in use on the Bayer Opera are not subject to interference from lipaemia; however, we recommend that where method sheets indicate interference from lipaemia then this should be quantified for the analyte in question.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">14560789</PMID><DateCreated><Year>2003</Year><Month>10</Month><Day>16</Day></DateCreated><DateCompleted><Year>2004</Year><Month>02</Month><Day>10</Day></DateCompleted><DateRevised><Year>2009</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0967-4845</ISSN><JournalIssue CitedMedium="Print"><Volume>60</Volume><Issue>3</Issue><PubDate><Year>2003</Year></PubDate></JournalIssue><Title>British journal of biomedical science</Title><ISOAbbreviation>Br. J. Biomed. Sci.</ISOAbbreviation></Journal><ArticleTitle>Lipaemia: an overrated interference?</ArticleTitle><Pagination><MedlinePgn>141-3</MedlinePgn></Pagination><Abstract><AbstractText>Reagent method sheets for analysis of common serum analytes often highlight the possibility of interference from lipaemia but the information given is often brief and may not be instrument-specific. Thus study assesses the degree of interference from lipaemia in a range of common serum analytes on the Bayer Opera (with a serum blank) using a commercial polymer, LipoClear, as a lipid-clearing agent. Serum samples (mean serum triglyceride 6.89 [range 0.58-28.4] mmol/L) are analysed for 14 common chemistry analytes and the results compared before and after treatment with LipoClear. Results showed no significant critical differences in analyte values before and after treatment, except for an expected fall in total protein, phosphate, cholesterol and triglyceride concentrations. Most of the common analytes in use on the Bayer Opera are not subject to interference from lipaemia; however, we recommend that where method sheets indicate interference from lipaemia then this should be quantified for the analyte in question.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Anderson</LastName><ForeName>N R</ForeName><Initials>NR</Initials><AffiliationInfo><Affiliation>Department of Clinical Chemistry, New Cross Hospital, Wolverhampton WV10 OQP, UK. neil.anderson@rwh-tr.nhs.uk</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Slim</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Gama</LastName><ForeName>R</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Holland</LastName><ForeName>M R</ForeName><Initials>MR</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Br J Biomed Sci</MedlineTA><NlmUniqueID>9309208</NlmUniqueID><ISSNLinking>0967-4845</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008055">Lipids</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011108">Polymers</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Br J Biomed Sci. 2004;61(4):218</RefSource><PMID Version="1">15649017</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016477">Artifacts</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D001774">Blood Chemical Analysis</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011232">Chemical Precipitation</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008055">Lipids</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000097">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011108">Polymers</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year><Month>10</Month><Day>17</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2004</Year><Month>2</Month><Day>11</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2003</Year><Month>10</Month><Day>17</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">14560789</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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