OperaV1, Main, Exploration, bibRecord, 001721

Organ preservation surgery for advanced unilateral glottic and subglottic cancer

Identifieur interne : 001721 ( Main/Exploration ); précédent : 001720; suivant : 001722

Organ preservation surgery for advanced unilateral glottic and subglottic cancer

Auteurs : Pierre Delaere [Belgique] ; Ann Goeleven [Belgique] ; Vincent Vander Poorten [Belgique] ; Robert Hermans [Belgique] ; Robert Hierner [Belgique] ; Jan Vranckx [Belgique]

Source :

The Laryngoscope [ 0023-852X ] ; 2007.

RBID : Pascal:07-0475045

Descripteurs français

Pascal (Inist)
- Cancer glotte, Tumeur maligne, Chondrosarcome, Chirurgie, Autotransplantation, Conservation organe, Stade avancé, Unilatéral, Sousglotte, Cartilage cricoïde, Trachée, Revascularisation, Traitement, Sarcome.
Wicri :
- topic : Chirurgie.

English descriptors

KwdEn :
- Advanced stage, Autotransplantation, Chondrosarcoma, Cricoid cartilage, Glottis cancer, Malignant tumor, Organ preservation, Revascularization, Sarcoma, Subglottis, Surgery, Trachea, Treatment, Unilateral.

Abstract

Objectives: Functional surgery of unilateral T_2b to T3 glottic cancer and cricoid chondrosarcoma is possible using the technique of tracheal autotransplantation. The objective of this paper is to report the functional and oncologic outcome of 24 consecutive patients treated with this technique between 2001 and 2007. Methods: Seventeen patients, of whom nine were previously irradiated, had unilateral glottic cancer with impaired mobility of the vocal fold. Clinical staging was T_2b to₃N₀. Seven patients had a chondrosarcoma of the cricoid cartilage. In a first operation, an extended hemilaryngectomy was performed, and a radial forearm flap, comprising a distal fascial and a proximal skin component, was transferred to the neck. The fascial paddle was wrapped around the upper 4-cm segment of cervical trachea, and the skin paddle was used for temporary closure of the extended hemilaryngectomy defect. The definitive reconstruction was performed after 2 to 3 months and consisted of removal of the skin paddle from the laryngeal defect and a transplantation of a patch of revascularized cervical trachea to reconstruct the laryngeal defect. Results: Swallowing and speech were restored after the first operation. The glottic and subglottic airway lumen was restored during the second opera; tion. The tracheostomy could be closed in 20 patients. After a median follow-up period of 33 (range, 1-66) months or almost 3 years, 23 patients remained free of tumor recurrence. Conclusions: Tracheal autotransplantation can be recommended as a functional treatment for selected T_2b to T₃ glottic cancers and for unilateral chondrosarcomas of the cricoid cartilage. The technique is oncologically robust while resulting in good postoperative function.

Affiliations:

Belgique

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Le document en format XML

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<author><name sortKey="Delaere, Pierre" sort="Delaere, Pierre" uniqKey="Delaere P" first="Pierre" last="Delaere">Pierre Delaere</name>
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<author><name sortKey="Goeleven, Ann" sort="Goeleven, Ann" uniqKey="Goeleven A" first="Ann" last="Goeleven">Ann Goeleven</name>
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<author><name sortKey="Vander Poorten, Vincent" sort="Vander Poorten, Vincent" uniqKey="Vander Poorten V" first="Vincent" last="Vander Poorten">Vincent Vander Poorten</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital K.U. Leuven</s1>
<s2>Leuven</s2>
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<country>Belgique</country>
<wicri:noRegion>Leuven</wicri:noRegion>
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<author><name sortKey="Hermans, Robert" sort="Hermans, Robert" uniqKey="Hermans R" first="Robert" last="Hermans">Robert Hermans</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Radiology, University Hospital K.U. Leuven</s1>
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<author><name sortKey="Hierner, Robert" sort="Hierner, Robert" uniqKey="Hierner R" first="Robert" last="Hierner">Robert Hierner</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Plastic and Reconstructive Surgery, University Hospital K.U. Leuven</s1>
<s2>Leuven</s2>
<s3>BEL</s3>
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<sZ>6 aut.</sZ>
</inist:fA14>
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<author><name sortKey="Vranckx, Jan" sort="Vranckx, Jan" uniqKey="Vranckx J" first="Jan" last="Vranckx">Jan Vranckx</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Plastic and Reconstructive Surgery, University Hospital K.U. Leuven</s1>
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<series><title level="j" type="main">The Laryngoscope</title>
<title level="j" type="abbreviated">Laryngoscope</title>
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<imprint><date when="2007">2007</date>
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<idno type="ISSN">0023-852X</idno>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Advanced stage</term>
<term>Autotransplantation</term>
<term>Chondrosarcoma</term>
<term>Cricoid cartilage</term>
<term>Glottis cancer</term>
<term>Malignant tumor</term>
<term>Organ preservation</term>
<term>Revascularization</term>
<term>Sarcoma</term>
<term>Subglottis</term>
<term>Surgery</term>
<term>Trachea</term>
<term>Treatment</term>
<term>Unilateral</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Cancer glotte</term>
<term>Tumeur maligne</term>
<term>Chondrosarcome</term>
<term>Chirurgie</term>
<term>Autotransplantation</term>
<term>Conservation organe</term>
<term>Stade avancé</term>
<term>Unilatéral</term>
<term>Sousglotte</term>
<term>Cartilage cricoïde</term>
<term>Trachée</term>
<term>Revascularisation</term>
<term>Traitement</term>
<term>Sarcome</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chirurgie</term>
</keywords>
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</teiHeader>
<front><div type="abstract" xml:lang="en">Objectives: Functional surgery of unilateral T<sub>2b</sub>
 to T3 glottic cancer and cricoid chondrosarcoma is possible using the technique of tracheal autotransplantation. The objective of this paper is to report the functional and oncologic outcome of 24 consecutive patients treated with this technique between 2001 and 2007. Methods: Seventeen patients, of whom nine were previously irradiated, had unilateral glottic cancer with impaired mobility of the vocal fold. Clinical staging was T<sub>2b</sub>
 to<sub> 3</sub>
N<sub>0</sub>
. Seven patients had a chondrosarcoma of the cricoid cartilage. In a first operation, an extended hemilaryngectomy was performed, and a radial forearm flap, comprising a distal fascial and a proximal skin component, was transferred to the neck. The fascial paddle was wrapped around the upper 4-cm segment of cervical trachea, and the skin paddle was used for temporary closure of the extended hemilaryngectomy defect. The definitive reconstruction was performed after 2 to 3 months and consisted of removal of the skin paddle from the laryngeal defect and a transplantation of a patch of revascularized cervical trachea to reconstruct the laryngeal defect. Results: Swallowing and speech were restored after the first operation. The glottic and subglottic airway lumen was restored during the second opera; tion. The tracheostomy could be closed in 20 patients. After a median follow-up period of 33 (range, 1-66) months or almost 3 years, 23 patients remained free of tumor recurrence. Conclusions: Tracheal autotransplantation can be recommended as a functional treatment for selected T<sub>2b</sub>
 to T<sub>3</sub>
 glottic cancers and for unilateral chondrosarcomas of the cricoid cartilage. The technique is oncologically robust while resulting in good postoperative function.</div>
</front>
</TEI>
<affiliations><list><country><li>Belgique</li>
</country>
</list>
<tree><country name="Belgique"><noRegion><name sortKey="Delaere, Pierre" sort="Delaere, Pierre" uniqKey="Delaere P" first="Pierre" last="Delaere">Pierre Delaere</name>
</noRegion>
<name sortKey="Goeleven, Ann" sort="Goeleven, Ann" uniqKey="Goeleven A" first="Ann" last="Goeleven">Ann Goeleven</name>
<name sortKey="Hermans, Robert" sort="Hermans, Robert" uniqKey="Hermans R" first="Robert" last="Hermans">Robert Hermans</name>
<name sortKey="Hierner, Robert" sort="Hierner, Robert" uniqKey="Hierner R" first="Robert" last="Hierner">Robert Hierner</name>
<name sortKey="Vander Poorten, Vincent" sort="Vander Poorten, Vincent" uniqKey="Vander Poorten V" first="Vincent" last="Vander Poorten">Vincent Vander Poorten</name>
<name sortKey="Vranckx, Jan" sort="Vranckx, Jan" uniqKey="Vranckx J" first="Jan" last="Vranckx">Jan Vranckx</name>
</country>
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</record>

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Organ preservation surgery for advanced unilateral glottic and subglottic cancer

Organ preservation surgery for advanced unilateral glottic and subglottic cancer

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

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