Phosphoinositides and vesicular membrane traffic
Identifieur interne : 000397 ( Main/Merge ); précédent : 000396; suivant : 000398Phosphoinositides and vesicular membrane traffic
Auteurs : Peter MayingerSource :
- Biochimica et Biophysica Acta [ 0006-3002 ] ; 2012.
Abstract
Phosphoinositide lipids were initially discovered as precursors for specific second messengers involved in signal transduction, but have now taken the center stage in controlling many essential processes at virtually every cellular membrane. In particular, phosphoinositides play a critical role in regulating membrane dynamics and vesicular transport. The unique distribution of certain phosphoinositides at specific intracellular membranes makes these molecules uniquely suited to direct organelle-specific trafficking reactions. In this regulatory role, phosphoinositides cooperate specifically with small GTPases from the Arf and Rab families. This review will summarize recent progress in the study of phosphoinositides in membrane trafficking and organellar organization and highlight the particular relevance of these signaling pathways in disease.
Url:
DOI: 10.1016/j.bbalip.2012.01.002
PubMed: 22281700
PubMed Central: 3340507
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000638
- to stream Pmc, to step Curation: 000638
- to stream Pmc, to step Checkpoint: 000254
- to stream Ncbi, to step Merge: 000514
- to stream Ncbi, to step Curation: 000514
- to stream Ncbi, to step Checkpoint: 000514
Links to Exploration step
PMC:3340507Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Phosphoinositides and vesicular membrane traffic</title><author><name sortKey="Mayinger, Peter" sort="Mayinger, Peter" uniqKey="Mayinger P" first="Peter" last="Mayinger">Peter Mayinger</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22281700</idno><idno type="pmc">3340507</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340507</idno><idno type="RBID">PMC:3340507</idno><idno type="doi">10.1016/j.bbalip.2012.01.002</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">000638</idno><idno type="wicri:Area/Pmc/Curation">000638</idno><idno type="wicri:Area/Pmc/Checkpoint">000254</idno><idno type="wicri:Area/Ncbi/Merge">000514</idno><idno type="wicri:Area/Ncbi/Curation">000514</idno><idno type="wicri:Area/Ncbi/Checkpoint">000514</idno><idno type="wicri:doubleKey">0006-3002:2012:Mayinger P:phosphoinositides:and:vesicular</idno><idno type="wicri:Area/Main/Merge">000397</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Phosphoinositides and vesicular membrane traffic</title><author><name sortKey="Mayinger, Peter" sort="Mayinger, Peter" uniqKey="Mayinger P" first="Peter" last="Mayinger">Peter Mayinger</name></author></analytic><series><title level="j">Biochimica et Biophysica Acta</title><idno type="ISSN">0006-3002</idno><idno type="e-ISSN">0006-3002</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Phosphoinositide lipids were initially discovered as precursors for specific second messengers involved in signal transduction, but have now taken the center stage in controlling many essential processes at virtually every cellular membrane. In particular, phosphoinositides play a critical role in regulating membrane dynamics and vesicular transport. The unique distribution of certain phosphoinositides at specific intracellular membranes makes these molecules uniquely suited to direct organelle-specific trafficking reactions. In this regulatory role, phosphoinositides cooperate specifically with small GTPases from the Arf and Rab families. This review will summarize recent progress in the study of phosphoinositides in membrane trafficking and organellar organization and highlight the particular relevance of these signaling pathways in disease.</p></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/MozartV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000397 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 000397 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Musique
|area= MozartV1
|flux= Main
|étape= Merge
|type= RBID
|clé= PMC:3340507
|texte= Phosphoinositides and vesicular membrane traffic
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:22281700" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \
| NlmPubMed2Wicri -a MozartV1
| This area was generated with Dilib version V0.6.20. |  |