Impaired awareness of movement disorders in Parkinson's disease.
Identifieur interne : 000040 ( Ncbi/Merge ); précédent : 000039; suivant : 000041Impaired awareness of movement disorders in Parkinson's disease.
Auteurs : Martina Amanzio [Italie] ; Silvia Monteverdi ; Alessandra Giordano ; Paola Soliveri ; Paola Filippi ; Giuliano GeminianiSource :
- Brain and cognition [ 1090-2147 ] ; 2010.
English descriptors
- KwdEn :
- Adult, Aged, Agnosia (complications), Agnosia (diagnosis), Agnosia (psychology), Analysis of Variance, Antiparkinson Agents (therapeutic use), Awareness, Female, Humans, Hypokinesia (etiology), Hypokinesia (psychology), Levodopa (therapeutic use), Middle Aged, Movement Disorders (classification), Movement Disorders (complications), Movement Disorders (psychology), Neuropsychological Tests, Parkinson Disease (complications), Parkinson Disease (drug therapy), Parkinson Disease (psychology), Self Concept, Statistics, Nonparametric.
- MESH :
- chemical , therapeutic use : Antiparkinson Agents, Levodopa.
- classification : Movement Disorders.
- complications : Agnosia, Movement Disorders, Parkinson Disease.
- diagnosis : Agnosia.
- drug therapy : Parkinson Disease.
- etiology : Hypokinesia.
- psychology : Agnosia, Hypokinesia, Movement Disorders, Parkinson Disease.
- Adult, Aged, Analysis of Variance, Awareness, Female, Humans, Middle Aged, Neuropsychological Tests, Self Concept, Statistics, Nonparametric.
Abstract
This study analyzed the presence of awareness of movement disorders (dyskinesias and hypokinesias) in 25 patients with Parkinson's disease (PD) and motor fluctuations (dyskinesias, wearing off, on-off fluctuations). Of the few studies that have dealt with this topic, none have analyzed the differences in the awareness of motor deficits by comparing the on and off states using motor scales and an extensive battery of tests to assess cognitive and behavioral functioning.
DOI: 10.1016/j.bandc.2009.10.011
PubMed: 19914762
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pubmed:19914762Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Impaired awareness of movement disorders in Parkinson's disease.</title><author><name sortKey="Amanzio, Martina" sort="Amanzio, Martina" uniqKey="Amanzio M" first="Martina" last="Amanzio">Martina Amanzio</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Torino, Via Verdi 10, 10123 Torino, Italy; Neuroscience Institute of Turin, NIT, University of Torino, Italy. amanzio@psych.unito.it</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Psychology, University of Torino, Via Verdi 10, 10123 Torino, Italy; Neuroscience Institute of Turin, NIT, University of Torino</wicri:regionArea><wicri:noRegion>University of Torino</wicri:noRegion></affiliation></author><author><name sortKey="Monteverdi, Silvia" sort="Monteverdi, Silvia" uniqKey="Monteverdi S" first="Silvia" last="Monteverdi">Silvia Monteverdi</name></author><author><name sortKey="Giordano, Alessandra" sort="Giordano, Alessandra" uniqKey="Giordano A" first="Alessandra" last="Giordano">Alessandra Giordano</name></author><author><name sortKey="Soliveri, Paola" sort="Soliveri, Paola" uniqKey="Soliveri P" first="Paola" last="Soliveri">Paola Soliveri</name></author><author><name sortKey="Filippi, Paola" sort="Filippi, Paola" uniqKey="Filippi P" first="Paola" last="Filippi">Paola Filippi</name></author><author><name sortKey="Geminiani, Giuliano" sort="Geminiani, Giuliano" uniqKey="Geminiani G" first="Giuliano" last="Geminiani">Giuliano Geminiani</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="doi">10.1016/j.bandc.2009.10.011</idno><idno type="RBID">pubmed:19914762</idno><idno type="pmid">19914762</idno><idno type="wicri:Area/PubMed/Corpus">000026</idno><idno type="wicri:Area/PubMed/Curation">000016</idno><idno type="wicri:Area/PubMed/Checkpoint">000011</idno><idno type="wicri:Area/Ncbi/Merge">000040</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Impaired awareness of movement disorders in Parkinson's disease.</title><author><name sortKey="Amanzio, Martina" sort="Amanzio, Martina" uniqKey="Amanzio M" first="Martina" last="Amanzio">Martina Amanzio</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of Torino, Via Verdi 10, 10123 Torino, Italy; Neuroscience Institute of Turin, NIT, University of Torino, Italy. amanzio@psych.unito.it</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Psychology, University of Torino, Via Verdi 10, 10123 Torino, Italy; Neuroscience Institute of Turin, NIT, University of Torino</wicri:regionArea><wicri:noRegion>University of Torino</wicri:noRegion></affiliation></author><author><name sortKey="Monteverdi, Silvia" sort="Monteverdi, Silvia" uniqKey="Monteverdi S" first="Silvia" last="Monteverdi">Silvia Monteverdi</name></author><author><name sortKey="Giordano, Alessandra" sort="Giordano, Alessandra" uniqKey="Giordano A" first="Alessandra" last="Giordano">Alessandra Giordano</name></author><author><name sortKey="Soliveri, Paola" sort="Soliveri, Paola" uniqKey="Soliveri P" first="Paola" last="Soliveri">Paola Soliveri</name></author><author><name sortKey="Filippi, Paola" sort="Filippi, Paola" uniqKey="Filippi P" first="Paola" last="Filippi">Paola Filippi</name></author><author><name sortKey="Geminiani, Giuliano" sort="Geminiani, Giuliano" uniqKey="Geminiani G" first="Giuliano" last="Geminiani">Giuliano Geminiani</name></author></analytic><series><title level="j">Brain and cognition</title><idno type="eISSN">1090-2147</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Agnosia (complications)</term><term>Agnosia (diagnosis)</term><term>Agnosia (psychology)</term><term>Analysis of Variance</term><term>Antiparkinson Agents (therapeutic use)</term><term>Awareness</term><term>Female</term><term>Humans</term><term>Hypokinesia (etiology)</term><term>Hypokinesia (psychology)</term><term>Levodopa (therapeutic use)</term><term>Middle Aged</term><term>Movement Disorders (classification)</term><term>Movement Disorders (complications)</term><term>Movement Disorders (psychology)</term><term>Neuropsychological Tests</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (drug therapy)</term><term>Parkinson Disease (psychology)</term><term>Self Concept</term><term>Statistics, Nonparametric</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiparkinson Agents</term><term>Levodopa</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Movement Disorders</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Agnosia</term><term>Movement Disorders</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Agnosia</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Hypokinesia</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Agnosia</term><term>Hypokinesia</term><term>Movement Disorders</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Analysis of Variance</term><term>Awareness</term><term>Female</term><term>Humans</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Self Concept</term><term>Statistics, Nonparametric</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This study analyzed the presence of awareness of movement disorders (dyskinesias and hypokinesias) in 25 patients with Parkinson's disease (PD) and motor fluctuations (dyskinesias, wearing off, on-off fluctuations). Of the few studies that have dealt with this topic, none have analyzed the differences in the awareness of motor deficits by comparing the on and off states using motor scales and an extensive battery of tests to assess cognitive and behavioral functioning.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">19914762</PMID><DateCreated><Year>2010</Year><Month>03</Month><Day>03</Day></DateCreated><DateCompleted><Year>2010</Year><Month>06</Month><Day>22</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1090-2147</ISSN><JournalIssue CitedMedium="Internet"><Volume>72</Volume><Issue>3</Issue><PubDate><Year>2010</Year><Month>Apr</Month></PubDate></JournalIssue><Title>Brain and cognition</Title><ISOAbbreviation>Brain Cogn</ISOAbbreviation></Journal><ArticleTitle>Impaired awareness of movement disorders in Parkinson's disease.</ArticleTitle><Pagination><MedlinePgn>337-46</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.bandc.2009.10.011</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">This study analyzed the presence of awareness of movement disorders (dyskinesias and hypokinesias) in 25 patients with Parkinson's disease (PD) and motor fluctuations (dyskinesias, wearing off, on-off fluctuations). Of the few studies that have dealt with this topic, none have analyzed the differences in the awareness of motor deficits by comparing the on and off states using motor scales and an extensive battery of tests to assess cognitive and behavioral functioning.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">PD patients were compared on three different scales that we have devised to measure awareness of movement disorders: Global Awareness of Movement (GAM) Disorders, dyskinesia/hypo-bradykinesia rating scales.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Data showed that PD patients had greater awareness and psychological suffering in the off state than in the on state. In particular, they were troubled by motor disabilities related to hypokinesias and had mood-related symptoms and a perception of disability in activities of daily living. Interestingly, patients only showed a selective reduction of awareness of movement disorders associated with executive functions and related to dyskinesias in the on state, compared to a preserved awareness of hypokinesias in the off state. On the contrary, no association with executive functions was found in the off state.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Our findings suggest that the dopaminergic overstimulation of mesocorticolimbic pathways may cause a dysfunction of prefrontal-subcortical connections related to the impaired insight.</AbstractText><CopyrightInformation>Copyright 2009 Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Amanzio</LastName><ForeName>Martina</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Psychology, University of Torino, Via Verdi 10, 10123 Torino, Italy; Neuroscience Institute of Turin, NIT, University of Torino, Italy. amanzio@psych.unito.it</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Monteverdi</LastName><ForeName>Silvia</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Giordano</LastName><ForeName>Alessandra</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Soliveri</LastName><ForeName>Paola</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Filippi</LastName><ForeName>Paola</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Geminiani</LastName><ForeName>Giuliano</ForeName><Initials>G</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2009</Year><Month>11</Month><Day>14</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Brain Cogn</MedlineTA><NlmUniqueID>8218014</NlmUniqueID><ISSNLinking>0278-2626</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000978">Antiparkinson Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>46627O600J</RegistryNumber><NameOfSubstance UI="D007980">Levodopa</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" 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UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D018476">Hypokinesia</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000209">etiology</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000523">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D007980">Levodopa</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009069">Movement Disorders</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000145">classification</QualifierName><QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName><QualifierName MajorTopicYN="N" UI="Q000523">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009483">Neuropsychological Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName><QualifierName MajorTopicYN="N" UI="Q000188">drug therapy</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000523">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012649">Self Concept</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D018709">Statistics, Nonparametric</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2008</Year><Month>11</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2009</Year><Month>10</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2009</Year><Month>10</Month><Day>19</Day></PubMedPubDate><PubMedPubDate PubStatus="aheadofprint"><Year>2009</Year><Month>11</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2009</Year><Month>11</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2009</Year><Month>11</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2010</Year><Month>6</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pii">S0278-2626(09)00203-6</ArticleId><ArticleId IdType="doi">10.1016/j.bandc.2009.10.011</ArticleId><ArticleId IdType="pubmed">19914762</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Italie</li></country></list><tree><noCountry><name sortKey="Filippi, Paola" sort="Filippi, Paola" uniqKey="Filippi P" first="Paola" last="Filippi">Paola Filippi</name><name sortKey="Geminiani, Giuliano" sort="Geminiani, Giuliano" uniqKey="Geminiani G" first="Giuliano" last="Geminiani">Giuliano Geminiani</name><name sortKey="Giordano, Alessandra" sort="Giordano, Alessandra" uniqKey="Giordano A" first="Alessandra" last="Giordano">Alessandra Giordano</name><name sortKey="Monteverdi, Silvia" sort="Monteverdi, Silvia" uniqKey="Monteverdi S" first="Silvia" last="Monteverdi">Silvia Monteverdi</name><name sortKey="Soliveri, Paola" sort="Soliveri, Paola" uniqKey="Soliveri P" first="Paola" last="Soliveri">Paola Soliveri</name></noCountry><country name="Italie"><noRegion><name sortKey="Amanzio, Martina" sort="Amanzio, Martina" uniqKey="Amanzio M" first="Martina" last="Amanzio">Martina Amanzio</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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