Pre- and postnatal exposures to pesticides and neurodevelopmental effects in children living in agricultural communities from South-Eastern Spain.
Identifieur interne : 000067 ( PubMed/Checkpoint ); précédent : 000066; suivant : 000068Pre- and postnatal exposures to pesticides and neurodevelopmental effects in children living in agricultural communities from South-Eastern Spain.
Auteurs : Beatriz González-Alzaga [Espagne] ; Antonio F. Hernández [Espagne] ; Miguel Rodríguez-Barranco [Espagne] ; Inmaculada G Mez [Espagne] ; Clemente Aguilar-Gardu O [Espagne] ; Inmaculada L Pez-Flores [Espagne] ; Tesif N Parr N [Espagne] ; Marina Lacasa A [Espagne]Source :
- Environment international [ 1873-6750 ] ; 2015.
Descripteurs français
- Wicri :
- geographic : Espagne.
English descriptors
- KwdEn :
- Agriculture, Child, Child Development (drug effects), Female, Geographic Information Systems, Humans, Male, Maternal Exposure (adverse effects), Organophosphorus Compounds (toxicity), Organophosphorus Compounds (urine), Pesticides (toxicity), Pesticides (urine), Pregnancy, Prenatal Exposure Delayed Effects (chemically induced), Prenatal Exposure Delayed Effects (urine), Random Allocation, Spain, Wechsler Scales.
- MESH :
- chemical , toxicity : Organophosphorus Compounds, Pesticides.
- geographic : Spain.
- adverse effects : Maternal Exposure.
- chemically induced : Prenatal Exposure Delayed Effects.
- drug effects : Child Development.
- chemical , urine : Organophosphorus Compounds, Pesticides, Prenatal Exposure Delayed Effects.
- Agriculture, Child, Female, Geographic Information Systems, Humans, Male, Pregnancy, Random Allocation, Wechsler Scales.
Abstract
Childrens exposure to neurotoxic compounds poses a major problem to public health because oftheir actively developing brain that makes them highly vulnerable. However, limited information is available on neuropsychological effects in children associated with pre- and postnatal exposures to pesticides.
DOI: 10.1016/j.envint.2015.09.019
PubMed: 26425806
Affiliations:
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Electronic address: marina.lacasana.easp@juntadeandalucia.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Andalusian School of Public Health (EASP), Granada, Spain; Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; CIBER of Epidemiology and Public Health (CIBERESP), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26425806</idno><idno type="pmid">26425806</idno><idno type="doi">10.1016/j.envint.2015.09.019</idno><idno type="wicri:Area/PubMed/Corpus">000055</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000055</idno><idno type="wicri:Area/PubMed/Curation">000055</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000055</idno><idno type="wicri:Area/PubMed/Checkpoint">000055</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000055</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Pre- and postnatal exposures to pesticides and neurodevelopmental effects in children living in agricultural communities from South-Eastern Spain.</title><author><name sortKey="Gonzalez Alzaga, Beatriz" sort="Gonzalez Alzaga, Beatriz" uniqKey="Gonzalez Alzaga B" first="Beatriz" last="González-Alzaga">Beatriz González-Alzaga</name><affiliation wicri:level="1"><nlm:affiliation>Andalusian School of Public Health (EASP), Granada, Spain; Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Andalusian School of Public Health (EASP), Granada, Spain; Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada</wicri:regionArea><wicri:noRegion>Granada</wicri:noRegion></affiliation></author><author><name sortKey="Hernandez, Antonio F" sort="Hernandez, Antonio F" uniqKey="Hernandez A" first="Antonio F" last="Hernández">Antonio F. Hernández</name><affiliation wicri:level="1"><nlm:affiliation>Department of Legal Medicine and Toxicology, University of Granada School of Medicine, Granada, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Legal Medicine and Toxicology, University of Granada School of Medicine, Granada</wicri:regionArea><wicri:noRegion>Granada</wicri:noRegion></affiliation></author><author><name sortKey="Rodriguez Barranco, Miguel" sort="Rodriguez Barranco, Miguel" uniqKey="Rodriguez Barranco M" first="Miguel" last="Rodríguez-Barranco">Miguel Rodríguez-Barranco</name><affiliation wicri:level="1"><nlm:affiliation>Andalusian School of Public Health (EASP), Granada, Spain; Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Andalusian School of Public Health (EASP), Granada, Spain; Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada</wicri:regionArea><wicri:noRegion>Granada</wicri:noRegion></affiliation></author><author><name sortKey="G Mez, Inmaculada" sort="G Mez, Inmaculada" uniqKey="G Mez I" first="Inmaculada" last="G Mez">Inmaculada G Mez</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurosciences, Faculty of Health Sciences, University of Almería, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neurosciences, Faculty of Health Sciences, University of Almería</wicri:regionArea><wicri:noRegion>University of Almería</wicri:noRegion></affiliation></author><author><name sortKey="Aguilar Gardu O, Clemente" sort="Aguilar Gardu O, Clemente" uniqKey="Aguilar Gardu O C" first="Clemente" last="Aguilar-Gardu O">Clemente Aguilar-Gardu O</name><affiliation wicri:level="1"><nlm:affiliation>Center for Public Health Research (CSISP-FISABIO), Valencia, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Center for Public Health Research (CSISP-FISABIO), Valencia</wicri:regionArea><wicri:noRegion>Valencia</wicri:noRegion></affiliation></author><author><name sortKey="L Pez Flores, Inmaculada" sort="L Pez Flores, Inmaculada" uniqKey="L Pez Flores I" first="Inmaculada" last="L Pez-Flores">Inmaculada L Pez-Flores</name><affiliation wicri:level="4"><nlm:affiliation>Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; Department of Genetics, Faculty of Sciences, University of Granada, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; Department of Genetics, Faculty of Sciences, University of Granada</wicri:regionArea><placeName><settlement type="city">Grenade (Espagne)</settlement><region nuts="2" type="region">Andalousie</region></placeName><orgName type="university">Université de Grenade</orgName></affiliation></author><author><name sortKey="Parr N, Tesif N" sort="Parr N, Tesif N" uniqKey="Parr N T" first="Tesif N" last="Parr N">Tesif N Parr N</name><affiliation wicri:level="1"><nlm:affiliation>University of Almería, Department of Neurosciences and Health Sciences, Almería, Spain; Andalusian Council of Health at Almería Province, Almería, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>University of Almería, Department of Neurosciences and Health Sciences, Almería, Spain; Andalusian Council of Health at Almería Province, Almería</wicri:regionArea><wicri:noRegion>Almería</wicri:noRegion></affiliation></author><author><name sortKey="Lacasa A, Marina" sort="Lacasa A, Marina" uniqKey="Lacasa A M" first="Marina" last="Lacasa A">Marina Lacasa A</name><affiliation wicri:level="3"><nlm:affiliation>Andalusian School of Public Health (EASP), Granada, Spain; Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain. Electronic address: marina.lacasana.easp@juntadeandalucia.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Andalusian School of Public Health (EASP), Granada, Spain; Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; CIBER of Epidemiology and Public Health (CIBERESP), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author></analytic><series><title level="j">Environment international</title><idno type="eISSN">1873-6750</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Agriculture</term><term>Child</term><term>Child Development (drug effects)</term><term>Female</term><term>Geographic Information Systems</term><term>Humans</term><term>Male</term><term>Maternal Exposure (adverse effects)</term><term>Organophosphorus Compounds (toxicity)</term><term>Organophosphorus Compounds (urine)</term><term>Pesticides (toxicity)</term><term>Pesticides (urine)</term><term>Pregnancy</term><term>Prenatal Exposure Delayed Effects (chemically induced)</term><term>Prenatal Exposure Delayed Effects (urine)</term><term>Random Allocation</term><term>Spain</term><term>Wechsler Scales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Organophosphorus Compounds</term><term>Pesticides</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Spain</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Maternal Exposure</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Prenatal Exposure Delayed Effects</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Child Development</term></keywords><keywords scheme="MESH" type="chemical" qualifier="urine" xml:lang="en"><term>Organophosphorus Compounds</term><term>Pesticides</term><term>Prenatal Exposure Delayed Effects</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Agriculture</term><term>Child</term><term>Female</term><term>Geographic Information Systems</term><term>Humans</term><term>Male</term><term>Pregnancy</term><term>Random Allocation</term><term>Wechsler Scales</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Childrens exposure to neurotoxic compounds poses a major problem to public health because oftheir actively developing brain that makes them highly vulnerable. However, limited information is available on neuropsychological effects in children associated with pre- and postnatal exposures to pesticides.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26425806</PMID><DateCreated><Year>2015</Year><Month>11</Month><Day>16</Day></DateCreated><DateCompleted><Year>2016</Year><Month>06</Month><Day>23</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>16</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-6750</ISSN><JournalIssue CitedMedium="Internet"><Volume>85</Volume><PubDate><Year>2015</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Environment international</Title><ISOAbbreviation>Environ Int</ISOAbbreviation></Journal><ArticleTitle>Pre- and postnatal exposures to pesticides and neurodevelopmental effects in children living in agricultural communities from South-Eastern Spain.</ArticleTitle><Pagination><MedlinePgn>229-37</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.envint.2015.09.019</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0160-4120(15)30059-3</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Childrens exposure to neurotoxic compounds poses a major problem to public health because oftheir actively developing brain that makes them highly vulnerable. However, limited information is available on neuropsychological effects in children associated with pre- and postnatal exposures to pesticides.</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate the association between current and pre- and postnatal exposures to pesticides and their effects on neurodevelopment in children aged 6–11 years living in agricultural communities from South-Eastern Spain.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">An ambispective study was conducted on 305 children aged 6–11 years randomly selected from public schools of the study area. Current exposure to organophosphate pesticides was assessed measuring children's urinary levels of dialkylphosphates (DAPs). Both prenatal and postnatal residential exposure to pesticides was estimated by developing a geographical information system (GIS) technology-based index that integrated distance-weighted measure of agricultural surface, time-series of crop areas per municipality and year, and land-use maps. Neuropsychological performance was evaluated with the Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV). The association of pre- and postnatal and current pesticide exposure with WISC-IV scale scores was assessed using multivariate linear regression models and generalized estimating equation (GEE) models, respectively.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Greater urinary DAP levels were associated with a poorer performance on intelligence quotient and verbal comprehension domain, with effects being more prominent in boys than in girls. The influence of an increase in 10 ha per year in crop surface around the child's residence during the postnatal period was associated with decreased intelligence quotient, processing speed and verbal comprehension scores. As regards prenatal exposure to pesticides, a poor processing speed performance was observed. These effects were also more prominent in boys than in girls.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Our results suggest that postnatal exposure to pesticides can negatively affect children's neuropsychological performance. Prenatal exposure was weakly associated to neurodevelopment impairment.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>González-Alzaga</LastName><ForeName>Beatriz</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Andalusian School of Public Health (EASP), Granada, Spain; Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hernández</LastName><ForeName>Antonio F</ForeName><Initials>AF</Initials><AffiliationInfo><Affiliation>Department of Legal Medicine and Toxicology, University of Granada School of Medicine, Granada, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rodríguez-Barranco</LastName><ForeName>Miguel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Andalusian School of Public Health (EASP), Granada, Spain; Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gómez</LastName><ForeName>Inmaculada</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Neurosciences, Faculty of Health Sciences, University of Almería, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aguilar-Garduño</LastName><ForeName>Clemente</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Center for Public Health Research (CSISP-FISABIO), Valencia, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>López-Flores</LastName><ForeName>Inmaculada</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; Department of Genetics, Faculty of Sciences, University of Granada, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Parrón</LastName><ForeName>Tesifón</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>University of Almería, Department of Neurosciences and Health Sciences, Almería, Spain; Andalusian Council of Health at Almería Province, Almería, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lacasaña</LastName><ForeName>Marina</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Andalusian School of Public Health (EASP), Granada, Spain; Instituto de Investigación Biosanitaria, ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain. Electronic address: marina.lacasana.easp@juntadeandalucia.es.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>09</Month><Day>29</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Environ Int</MedlineTA><NlmUniqueID>7807270</NlmUniqueID><ISSNLinking>0160-4120</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D009943">Organophosphorus Compounds</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010575">Pesticides</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000383" MajorTopicYN="N">Agriculture</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002657" MajorTopicYN="N">Child Development</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D040362" MajorTopicYN="N">Geographic Information Systems</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018811" MajorTopicYN="N">Maternal Exposure</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009943" MajorTopicYN="N">Organophosphorus Compounds</DescriptorName><QualifierName UI="Q000633" MajorTopicYN="Y">toxicity</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010575" MajorTopicYN="N">Pesticides</DescriptorName><QualifierName UI="Q000633" MajorTopicYN="Y">toxicity</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011247" MajorTopicYN="N">Pregnancy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011297" MajorTopicYN="N">Prenatal Exposure Delayed Effects</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011897" MajorTopicYN="N">Random Allocation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N" Type="Geographic">Spain</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014888" MajorTopicYN="Y">Wechsler Scales</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Children</Keyword><Keyword MajorTopicYN="N">Environmental</Keyword><Keyword MajorTopicYN="N">Neuropsychological development</Keyword><Keyword MajorTopicYN="N">Neurotoxicity</Keyword><Keyword MajorTopicYN="N">Pesticides</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>06</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2015</Year><Month>09</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>09</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>10</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>10</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>6</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26425806</ArticleId><ArticleId IdType="pii">S0160-4120(15)30059-3</ArticleId><ArticleId IdType="doi">10.1016/j.envint.2015.09.019</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Espagne</li></country><region><li>Andalousie</li><li>Communauté de Madrid</li></region><settlement><li>Grenade (Espagne)</li><li>Madrid</li></settlement><orgName><li>Université de Grenade</li></orgName></list><tree><country name="Espagne"><noRegion><name sortKey="Gonzalez Alzaga, Beatriz" sort="Gonzalez Alzaga, Beatriz" uniqKey="Gonzalez Alzaga B" first="Beatriz" last="González-Alzaga">Beatriz González-Alzaga</name></noRegion><name sortKey="Aguilar Gardu O, Clemente" sort="Aguilar Gardu O, Clemente" uniqKey="Aguilar Gardu O C" first="Clemente" last="Aguilar-Gardu O">Clemente Aguilar-Gardu O</name><name sortKey="G Mez, Inmaculada" sort="G Mez, Inmaculada" uniqKey="G Mez I" first="Inmaculada" last="G Mez">Inmaculada G Mez</name><name sortKey="Hernandez, Antonio F" sort="Hernandez, Antonio F" uniqKey="Hernandez A" first="Antonio F" last="Hernández">Antonio F. Hernández</name><name sortKey="L Pez Flores, Inmaculada" sort="L Pez Flores, Inmaculada" uniqKey="L Pez Flores I" first="Inmaculada" last="L Pez-Flores">Inmaculada L Pez-Flores</name><name sortKey="Lacasa A, Marina" sort="Lacasa A, Marina" uniqKey="Lacasa A M" first="Marina" last="Lacasa A">Marina Lacasa A</name><name sortKey="Parr N, Tesif N" sort="Parr N, Tesif N" uniqKey="Parr N T" first="Tesif N" last="Parr N">Tesif N Parr N</name><name sortKey="Rodriguez Barranco, Miguel" sort="Rodriguez Barranco, Miguel" uniqKey="Rodriguez Barranco M" first="Miguel" last="Rodríguez-Barranco">Miguel Rodríguez-Barranco</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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