Neural Tube Defects and Maternal Residential Proximity to Agricultural Pesticide Applications
Identifieur interne : 000603 ( Istex/Checkpoint ); précédent : 000602; suivant : 000604Neural Tube Defects and Maternal Residential Proximity to Agricultural Pesticide Applications
Auteurs : Rudolph P. Rull [États-Unis] ; Beate Ritz [États-Unis] ; Gary M. Shaw [États-Unis]Source :
- American Journal of Epidemiology [ 0002-9262 ] ; 2006-04-15.
English descriptors
- KwdEn :
Abstract
Residential proximity to applications of agricultural pesticides may be an important source of exposure to agents that have been classified as developmental toxins. Data on two case-control study populations of infants with neural tube defects (NTDs) and nonmalformed controls delivered in California between 1987 and 1991 were pooled to investigate whether maternal residential proximity to applications of specific pesticides or physicochemical groups of pesticides during early gestation increases the risk of these malformations. Maternal residential proximity within 1,000 m of pesticide applications was ascertained by linking mothers' addresses with agricultural pesticide use reports and crop maps. Odds ratios were computed by using conventional single- and multiple-pesticide and hierarchical multiple-pesticide logistic regression. In single-pesticide models, several pesticides were associated with NTDs after adjustment for study population, maternal ethnicity, educational level, cigarette smoking, and vitamin use. In a hierarchical multiple-pesticide model, effect estimates for only benomyl and methomyl suggested a possible association. Elevated risks of NTDs and anencephaly or spina bifida subtypes were also associated with exposures to chemicals classified as amide, benzimidazole, methyl carbamate, or organophosphorus pesticides and with increasing numbers of pesticides. These results suggest that ambient exposure to certain categories of agricultural pesticides may increase the risk of NTDs.
Url:
DOI: 10.1093/aje/kwj101
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
ISTEX:1A4048FDBC9D759942C6CFBAF613DB6BAB7A30FBLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Neural Tube Defects and Maternal Residential Proximity to Agricultural Pesticide Applications</title>
<author><name sortKey="Rull, Rudolph P" sort="Rull, Rudolph P" uniqKey="Rull R" first="Rudolph P." last="Rull">Rudolph P. Rull</name>
</author>
<author><name sortKey="Ritz, Beate" sort="Ritz, Beate" uniqKey="Ritz B" first="Beate" last="Ritz">Beate Ritz</name>
</author>
<author><name sortKey="Shaw, Gary M" sort="Shaw, Gary M" uniqKey="Shaw G" first="Gary M." last="Shaw">Gary M. Shaw</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:1A4048FDBC9D759942C6CFBAF613DB6BAB7A30FB</idno>
<date when="2006" year="2006">2006</date>
<idno type="doi">10.1093/aje/kwj101</idno>
<idno type="url">https://api.istex.fr/document/1A4048FDBC9D759942C6CFBAF613DB6BAB7A30FB/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001380</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001380</idno>
<idno type="wicri:Area/Istex/Curation">001293</idno>
<idno type="wicri:Area/Istex/Checkpoint">000603</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000603</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Neural Tube Defects and Maternal Residential Proximity to Agricultural Pesticide Applications</title>
<author><name sortKey="Rull, Rudolph P" sort="Rull, Rudolph P" uniqKey="Rull R" first="Rudolph P." last="Rull">Rudolph P. Rull</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Northern California Cancer Center, Berkeley</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Department of Epidemiology, School of Public Health, University of California at Los Angeles, Los Angeles</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Ritz, Beate" sort="Ritz, Beate" uniqKey="Ritz B" first="Beate" last="Ritz">Beate Ritz</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Department of Epidemiology, School of Public Health, University of California at Los Angeles, Los Angeles</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Department of Environmental Health Sciences, School of Public Health, University of California at Los Angeles, Los Angeles</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Shaw, Gary M" sort="Shaw, Gary M" uniqKey="Shaw G" first="Gary M." last="Shaw">Gary M. Shaw</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>California Birth Defects Monitoring Program, March of Dimes Birth Defects Foundation, Berkeley</wicri:cityArea>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">American Journal of Epidemiology</title>
<title level="j" type="abbrev">Am. J. Epidemiol.</title>
<idno type="ISSN">0002-9262</idno>
<idno type="eISSN">1476-6256</idno>
<imprint><publisher>Oxford University Press</publisher>
<date type="published" when="2006-04-15">2006-04-15</date>
<biblScope unit="volume">163</biblScope>
<biblScope unit="issue">8</biblScope>
<biblScope unit="page" from="743">743</biblScope>
<biblScope unit="page" to="753">753</biblScope>
</imprint>
<idno type="ISSN">0002-9262</idno>
</series>
<idno type="istex">1A4048FDBC9D759942C6CFBAF613DB6BAB7A30FB</idno>
<idno type="DOI">10.1093/aje/kwj101</idno>
<idno type="local">kwj101</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0002-9262</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>CI, confidence interval</term>
<term>NTD, neural tube defect</term>
<term>OR, odds ratio</term>
<term>anencephaly</term>
<term>crops, agricultural</term>
<term>environmental exposure</term>
<term>geographic information systems</term>
<term>maternal exposure</term>
<term>neural tube defects</term>
<term>pesticides</term>
<term>spina dysraphism</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Residential proximity to applications of agricultural pesticides may be an important source of exposure to agents that have been classified as developmental toxins. Data on two case-control study populations of infants with neural tube defects (NTDs) and nonmalformed controls delivered in California between 1987 and 1991 were pooled to investigate whether maternal residential proximity to applications of specific pesticides or physicochemical groups of pesticides during early gestation increases the risk of these malformations. Maternal residential proximity within 1,000 m of pesticide applications was ascertained by linking mothers' addresses with agricultural pesticide use reports and crop maps. Odds ratios were computed by using conventional single- and multiple-pesticide and hierarchical multiple-pesticide logistic regression. In single-pesticide models, several pesticides were associated with NTDs after adjustment for study population, maternal ethnicity, educational level, cigarette smoking, and vitamin use. In a hierarchical multiple-pesticide model, effect estimates for only benomyl and methomyl suggested a possible association. Elevated risks of NTDs and anencephaly or spina bifida subtypes were also associated with exposures to chemicals classified as amide, benzimidazole, methyl carbamate, or organophosphorus pesticides and with increasing numbers of pesticides. These results suggest that ambient exposure to certain categories of agricultural pesticides may increase the risk of NTDs.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Californie</li>
</region>
</list>
<tree><country name="États-Unis"><region name="Californie"><name sortKey="Rull, Rudolph P" sort="Rull, Rudolph P" uniqKey="Rull R" first="Rudolph P." last="Rull">Rudolph P. Rull</name>
</region>
<name sortKey="Ritz, Beate" sort="Ritz, Beate" uniqKey="Ritz B" first="Beate" last="Ritz">Beate Ritz</name>
<name sortKey="Ritz, Beate" sort="Ritz, Beate" uniqKey="Ritz B" first="Beate" last="Ritz">Beate Ritz</name>
<name sortKey="Rull, Rudolph P" sort="Rull, Rudolph P" uniqKey="Rull R" first="Rudolph P." last="Rull">Rudolph P. Rull</name>
<name sortKey="Shaw, Gary M" sort="Shaw, Gary M" uniqKey="Shaw G" first="Gary M." last="Shaw">Gary M. Shaw</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Agronomie/explor/SisAgriV1/Data/Istex/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000603 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Checkpoint/biblio.hfd -nk 000603 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Agronomie |area= SisAgriV1 |flux= Istex |étape= Checkpoint |type= RBID |clé= ISTEX:1A4048FDBC9D759942C6CFBAF613DB6BAB7A30FB |texte= Neural Tube Defects and Maternal Residential Proximity to Agricultural Pesticide Applications }}
![]() | This area was generated with Dilib version V0.6.28. | ![]() |