Identification and differentiation of surgically correctable hypertension due to primary aldosteronism
Identifieur interne : 003D00 ( Main/Exploration ); précédent : 003C99; suivant : 003D01Identification and differentiation of surgically correctable hypertension due to primary aldosteronism
Auteurs : Steven M. Herf [États-Unis] ; David C. Teates [États-Unis] ; Charles J. Tegtmeyer [États-Unis] ; E. Darrocott Vaughan Jr. [États-Unis] ; Carlos R. Ayers [États-Unis] ; Robert M. Carey [États-Unis]Source :
- The American Journal of Medicine [ 0002-9343 ] ; 1979.
Abstract
During a protocol study for the evaluation of patients with primary aldosteronism, a variety of diagnostic studies were employed in an attempt to identify patients with primary aldosteronism and to differentiate patients with adrenal adenoma from patients with idiopathic adrenal hyperplasia. In this study, we are able to demonstrate the utility of (1) absent postural increase in plasma aldosterone concentration, (2) adrenal scanning and (3) normalization of blood pressure with spironolactone therapy in identifying patients with primary aldosterone excess who have an adrenal adenoma, surgical removal of which results in eliminating their hypertension.
Url:
DOI: 10.1016/0002-9343(79)90785-X
Affiliations:
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<front><div type="abstract" xml:lang="en">During a protocol study for the evaluation of patients with primary aldosteronism, a variety of diagnostic studies were employed in an attempt to identify patients with primary aldosteronism and to differentiate patients with adrenal adenoma from patients with idiopathic adrenal hyperplasia. In this study, we are able to demonstrate the utility of (1) absent postural increase in plasma aldosterone concentration, (2) adrenal scanning and (3) normalization of blood pressure with spironolactone therapy in identifying patients with primary aldosterone excess who have an adrenal adenoma, surgical removal of which results in eliminating their hypertension.</div>
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