Studies on the mechanism of clinical tolerance in solar urticaria
Identifieur interne : 002577 ( Istex/Corpus ); précédent : 002576; suivant : 002578Studies on the mechanism of clinical tolerance in solar urticaria
Auteurs : T. M. Keahey ; R. M. Lavker ; Kaysh. Kaidbey ; P. C. Atkins ; B. ZweimanSource :
- British Journal of Dermatology [ 0007-0963 ] ; 1984-03.
Abstract
Tolerance to artificial ultraviolet radiation (UVR) was induced in three patients with solar urticaria by administering graded whole body exposures to long‐wave ultraviolet radiation (UV‐A, 320–400 nm) in a phototherapy cabinet. Plasma histamine levels, mast cell ultrastructure and cutaneous responses to intradermally injected codeine and histamine were examined before and after the induction of tolerance. No evidence of serum complement activation could be demonstrated following exposure of serum samples to UVR in vitro. These studies suggest that the state of tolerance is due neither to mediator (histamine) depletion nor to a systemic effect induced by UV‐A but may be due to an increase in the mast cell degranulation threshold.
Url:
DOI: 10.1111/j.1365-2133.1984.tb04639.x
Links to Exploration step
ISTEX:28FE249E676DA1AE86729AF76FF96BAA935709A4Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Studies on the mechanism of clinical tolerance in solar urticaria</title>
<author><name sortKey="Keahey, T M" sort="Keahey, T M" uniqKey="Keahey T" first="T. M." last="Keahey">T. M. Keahey</name>
<affiliation><mods:affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</mods:affiliation>
</affiliation>
</author>
<author><name sortKey="Lavker, R M" sort="Lavker, R M" uniqKey="Lavker R" first="R. M." last="Lavker">R. M. Lavker</name>
<affiliation><mods:affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</mods:affiliation>
</affiliation>
</author>
<author><name sortKey="Kaidbey, Kaysh" sort="Kaidbey, Kaysh" uniqKey="Kaidbey K" first="Kaysh." last="Kaidbey">Kaysh. Kaidbey</name>
<affiliation><mods:affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</mods:affiliation>
</affiliation>
</author>
<author><name sortKey="Atkins, P C" sort="Atkins, P C" uniqKey="Atkins P" first="P. C." last="Atkins">P. C. Atkins</name>
<affiliation><mods:affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</mods:affiliation>
</affiliation>
</author>
<author><name sortKey="Zweiman, B" sort="Zweiman, B" uniqKey="Zweiman B" first="B." last="Zweiman">B. Zweiman</name>
<affiliation><mods:affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</mods:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:28FE249E676DA1AE86729AF76FF96BAA935709A4</idno>
<date when="1984" year="1984">1984</date>
<idno type="doi">10.1111/j.1365-2133.1984.tb04639.x</idno>
<idno type="url">https://api.istex.fr/document/28FE249E676DA1AE86729AF76FF96BAA935709A4/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">002577</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Studies on the mechanism of clinical tolerance in solar urticaria</title>
<author><name sortKey="Keahey, T M" sort="Keahey, T M" uniqKey="Keahey T" first="T. M." last="Keahey">T. M. Keahey</name>
<affiliation><mods:affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</mods:affiliation>
</affiliation>
</author>
<author><name sortKey="Lavker, R M" sort="Lavker, R M" uniqKey="Lavker R" first="R. M." last="Lavker">R. M. Lavker</name>
<affiliation><mods:affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</mods:affiliation>
</affiliation>
</author>
<author><name sortKey="Kaidbey, Kaysh" sort="Kaidbey, Kaysh" uniqKey="Kaidbey K" first="Kaysh." last="Kaidbey">Kaysh. Kaidbey</name>
<affiliation><mods:affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</mods:affiliation>
</affiliation>
</author>
<author><name sortKey="Atkins, P C" sort="Atkins, P C" uniqKey="Atkins P" first="P. C." last="Atkins">P. C. Atkins</name>
<affiliation><mods:affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</mods:affiliation>
</affiliation>
</author>
<author><name sortKey="Zweiman, B" sort="Zweiman, B" uniqKey="Zweiman B" first="B." last="Zweiman">B. Zweiman</name>
<affiliation><mods:affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</mods:affiliation>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">British Journal of Dermatology</title>
<idno type="ISSN">0007-0963</idno>
<idno type="eISSN">1365-2133</idno>
<imprint><publisher>Blackwell Publishing Ltd</publisher>
<pubPlace>Oxford, UK</pubPlace>
<date type="published" when="1984-03">1984-03</date>
<biblScope unit="volume">110</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="327">327</biblScope>
<biblScope unit="page" to="338">338</biblScope>
</imprint>
<idno type="ISSN">0007-0963</idno>
</series>
<idno type="istex">28FE249E676DA1AE86729AF76FF96BAA935709A4</idno>
<idno type="DOI">10.1111/j.1365-2133.1984.tb04639.x</idno>
<idno type="ArticleID">BJD327</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0007-0963</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Tolerance to artificial ultraviolet radiation (UVR) was induced in three patients with solar urticaria by administering graded whole body exposures to long‐wave ultraviolet radiation (UV‐A, 320–400 nm) in a phototherapy cabinet. Plasma histamine levels, mast cell ultrastructure and cutaneous responses to intradermally injected codeine and histamine were examined before and after the induction of tolerance. No evidence of serum complement activation could be demonstrated following exposure of serum samples to UVR in vitro. These studies suggest that the state of tolerance is due neither to mediator (histamine) depletion nor to a systemic effect induced by UV‐A but may be due to an increase in the mast cell degranulation threshold.</div>
</front>
</TEI>
<istex><corpusName>wiley</corpusName>
<author><json:item><name>T.M. KEAHEY</name>
<affiliations><json:string>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</json:string>
</affiliations>
</json:item>
<json:item><name>R.M. LAVKER</name>
<affiliations><json:string>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</json:string>
</affiliations>
</json:item>
<json:item><name>KAYSH. KAIDBEY</name>
<affiliations><json:string>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</json:string>
</affiliations>
</json:item>
<json:item><name>P.C. ATKINS</name>
<affiliations><json:string>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</json:string>
</affiliations>
</json:item>
<json:item><name>B. ZWEIMAN</name>
<affiliations><json:string>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</json:string>
</affiliations>
</json:item>
</author>
<articleId><json:string>BJD327</json:string>
</articleId>
<language><json:string>eng</json:string>
</language>
<abstract>Tolerance to artificial ultraviolet radiation (UVR) was induced in three patients with solar urticaria by administering graded whole body exposures to long‐wave ultraviolet radiation (UV‐A, 320–400 nm) in a phototherapy cabinet. Plasma histamine levels, mast cell ultrastructure and cutaneous responses to intradermally injected codeine and histamine were examined before and after the induction of tolerance. No evidence of serum complement activation could be demonstrated following exposure of serum samples to UVR in vitro. These studies suggest that the state of tolerance is due neither to mediator (histamine) depletion nor to a systemic effect induced by UV‐A but may be due to an increase in the mast cell degranulation threshold.</abstract>
<qualityIndicators><score>6.136</score>
<pdfVersion>1.4</pdfVersion>
<pdfPageSize>497 x 695 pts</pdfPageSize>
<refBibsNative>true</refBibsNative>
<keywordCount>0</keywordCount>
<abstractCharCount>739</abstractCharCount>
<pdfWordCount>4328</pdfWordCount>
<pdfCharCount>26381</pdfCharCount>
<pdfPageCount>13</pdfPageCount>
<abstractWordCount>109</abstractWordCount>
</qualityIndicators>
<title>Studies on the mechanism of clinical tolerance in solar urticaria</title>
<genre><json:string>article</json:string>
</genre>
<host><volume>110</volume>
<publisherId><json:string>BJD</json:string>
</publisherId>
<pages><total>12</total>
<last>338</last>
<first>327</first>
</pages>
<issn><json:string>0007-0963</json:string>
</issn>
<issue>3</issue>
<genre><json:string>Journal</json:string>
</genre>
<language><json:string>unknown</json:string>
</language>
<eissn><json:string>1365-2133</json:string>
</eissn>
<title>British Journal of Dermatology</title>
<doi><json:string>10.1111/(ISSN)1365-2133</json:string>
</doi>
</host>
<publicationDate>1984</publicationDate>
<copyrightDate>1984</copyrightDate>
<doi><json:string>10.1111/j.1365-2133.1984.tb04639.x</json:string>
</doi>
<id>28FE249E676DA1AE86729AF76FF96BAA935709A4</id>
<fulltext><json:item><original>true</original>
<mimetype>application/pdf</mimetype>
<extension>pdf</extension>
<uri>https://api.istex.fr/document/28FE249E676DA1AE86729AF76FF96BAA935709A4/fulltext/pdf</uri>
</json:item>
<json:item><original>false</original>
<mimetype>application/zip</mimetype>
<extension>zip</extension>
<uri>https://api.istex.fr/document/28FE249E676DA1AE86729AF76FF96BAA935709A4/fulltext/zip</uri>
</json:item>
<istex:fulltextTEI uri="https://api.istex.fr/document/28FE249E676DA1AE86729AF76FF96BAA935709A4/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Studies on the mechanism of clinical tolerance in solar urticaria</title>
</titleStmt>
<publicationStmt><authority>ISTEX</authority>
<publisher>Blackwell Publishing Ltd</publisher>
<pubPlace>Oxford, UK</pubPlace>
<availability><p>WILEY</p>
</availability>
<date>1984</date>
</publicationStmt>
<sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Studies on the mechanism of clinical tolerance in solar urticaria</title>
<author><persName><forename type="first">T.M.</forename>
<surname>KEAHEY</surname>
</persName>
<note type="correspondence"><p>Correspondence: Dr Thomas Keahey, National Institute of Health, Building 10, Room 11C207, Bethesda, MD 20205, U.S.A.</p>
</note>
<affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</affiliation>
</author>
<author><persName><forename type="first">R.M.</forename>
<surname>LAVKER</surname>
</persName>
<affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</affiliation>
</author>
<author><persName><forename type="first">KAYSH.</forename>
<surname>KAIDBEY</surname>
</persName>
<affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</affiliation>
</author>
<author><persName><forename type="first">P.C.</forename>
<surname>ATKINS</surname>
</persName>
<affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</affiliation>
</author>
<author><persName><forename type="first">B.</forename>
<surname>ZWEIMAN</surname>
</persName>
<affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</affiliation>
</author>
</analytic>
<monogr><title level="j">British Journal of Dermatology</title>
<idno type="pISSN">0007-0963</idno>
<idno type="eISSN">1365-2133</idno>
<idno type="DOI">10.1111/(ISSN)1365-2133</idno>
<imprint><publisher>Blackwell Publishing Ltd</publisher>
<pubPlace>Oxford, UK</pubPlace>
<date type="published" when="1984-03"></date>
<biblScope unit="volume">110</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="327">327</biblScope>
<biblScope unit="page" to="338">338</biblScope>
</imprint>
</monogr>
<idno type="istex">28FE249E676DA1AE86729AF76FF96BAA935709A4</idno>
<idno type="DOI">10.1111/j.1365-2133.1984.tb04639.x</idno>
<idno type="ArticleID">BJD327</idno>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><creation><date>1984</date>
</creation>
<langUsage><language ident="en">en</language>
</langUsage>
<abstract xml:lang="en"><p>Tolerance to artificial ultraviolet radiation (UVR) was induced in three patients with solar urticaria by administering graded whole body exposures to long‐wave ultraviolet radiation (UV‐A, 320–400 nm) in a phototherapy cabinet. Plasma histamine levels, mast cell ultrastructure and cutaneous responses to intradermally injected codeine and histamine were examined before and after the induction of tolerance. No evidence of serum complement activation could be demonstrated following exposure of serum samples to UVR in vitro. These studies suggest that the state of tolerance is due neither to mediator (histamine) depletion nor to a systemic effect induced by UV‐A but may be due to an increase in the mast cell degranulation threshold.</p>
</abstract>
</profileDesc>
<revisionDesc><change when="1984-03">Published</change>
</revisionDesc>
</teiHeader>
</istex:fulltextTEI>
<json:item><original>false</original>
<mimetype>text/plain</mimetype>
<extension>txt</extension>
<uri>https://api.istex.fr/document/28FE249E676DA1AE86729AF76FF96BAA935709A4/fulltext/txt</uri>
</json:item>
</fulltext>
<metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration>
<istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName>
<publisherLoc>Oxford, UK</publisherLoc>
</publisherInfo>
<doi origin="wiley" registered="yes">10.1111/(ISSN)1365-2133</doi>
<issn type="print">0007-0963</issn>
<issn type="electronic">1365-2133</issn>
<idGroup><id type="product" value="BJD"></id>
<id type="publisherDivision" value="ST"></id>
</idGroup>
<titleGroup><title type="main" sort="BRITISH JOURNAL OF DERMATOLOGY">British Journal of Dermatology</title>
</titleGroup>
</publicationMeta>
<publicationMeta level="part" position="03003"><doi origin="wiley">10.1111/bjd.1984.110.issue-3</doi>
<numberingGroup><numbering type="journalVolume" number="110">110</numbering>
<numbering type="journalIssue" number="3">3</numbering>
</numberingGroup>
<coverDate startDate="1984-03">March 1984</coverDate>
</publicationMeta>
<publicationMeta level="unit" type="article" position="0032700" status="forIssue"><doi origin="wiley">10.1111/j.1365-2133.1984.tb04639.x</doi>
<idGroup><id type="unit" value="BJD327"></id>
</idGroup>
<countGroup><count type="pageTotal" number="12"></count>
</countGroup>
<titleGroup><title type="tocHeading1">Clinical and Laboratory Investigations</title>
</titleGroup>
<eventGroup><event type="firstOnline" date="2006-07-29"></event>
<event type="publishedOnlineFinalForm" date="2006-07-29"></event>
<event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.2 mode:FullText source:HeaderRef result:HeaderRef" date="2010-03-08"></event>
<event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:4.0.1" date="2014-03-15"></event>
<event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-15"></event>
</eventGroup>
<numberingGroup><numbering type="pageFirst" number="327">327</numbering>
<numbering type="pageLast" number="338">338</numbering>
</numberingGroup>
<correspondenceTo>Dr Thomas Keahey, National Institute of Health, Building 10, Room 11C207, Bethesda, MD 20205, U.S.A.</correspondenceTo>
<linkGroup><link type="toTypesetVersion" href="file:BJD.BJD327.pdf"></link>
</linkGroup>
</publicationMeta>
<contentMeta><unparsedEditorialHistory>Accepted for publication 30 August 1983</unparsedEditorialHistory>
<countGroup><count type="referenceTotal" number="12"></count>
<count type="linksCrossRef" number="6"></count>
</countGroup>
<titleGroup><title type="main">Studies on the mechanism of clinical tolerance in solar urticaria</title>
</titleGroup>
<creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1" corresponding="yes"><personName><givenNames>T.M.</givenNames>
<familyName>KEAHEY</familyName>
</personName>
</creator>
<creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>R.M.</givenNames>
<familyName>LAVKER</familyName>
</personName>
</creator>
<creator creatorRole="author" xml:id="cr3" affiliationRef="#a1"><personName><givenNames>KAYSH.</givenNames>
<familyName>KAIDBEY</familyName>
</personName>
</creator>
<creator creatorRole="author" xml:id="cr4" affiliationRef="#a1"><personName><givenNames>P.C.</givenNames>
<familyName>ATKINS</familyName>
</personName>
</creator>
<creator creatorRole="author" xml:id="cr5" affiliationRef="#a1"><personName><givenNames>B.</givenNames>
<familyName>ZWEIMAN</familyName>
</personName>
</creator>
</creators>
<affiliationGroup><affiliation xml:id="a1" countryCode="US"><unparsedAffiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</unparsedAffiliation>
</affiliation>
</affiliationGroup>
<abstractGroup><abstract type="main" xml:lang="en"><title type="main">SUMMARY</title>
<p>Tolerance to artificial ultraviolet radiation (UVR) was induced in three patients with solar urticaria by administering graded whole body exposures to long‐wave ultraviolet radiation (UV‐A, 320–400 nm) in a phototherapy cabinet. Plasma histamine levels, mast cell ultrastructure and cutaneous responses to intradermally injected codeine and histamine were examined before and after the induction of tolerance. No evidence of serum complement activation could be demonstrated following exposure of serum samples to UVR <i>in vitro</i>
. These studies suggest that the state of tolerance is due neither to mediator (histamine) depletion nor to a systemic effect induced by UV‐A but may be due to an increase in the mast cell degranulation threshold.</p>
</abstract>
</abstractGroup>
</contentMeta>
</header>
</component>
</istex:document>
</istex:metadataXml>
<mods version="3.6"><titleInfo lang="en"><title>Studies on the mechanism of clinical tolerance in solar urticaria</title>
</titleInfo>
<titleInfo type="alternative" contentType="CDATA" lang="en"><title>Studies on the mechanism of clinical tolerance in solar urticaria</title>
</titleInfo>
<name type="personal"><namePart type="given">T.M.</namePart>
<namePart type="family">KEAHEY</namePart>
<affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</affiliation>
<description>Correspondence: Dr Thomas Keahey, National Institute of Health, Building 10, Room 11C207, Bethesda, MD 20205, U.S.A.</description>
<role><roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal"><namePart type="given">R.M.</namePart>
<namePart type="family">LAVKER</namePart>
<affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</affiliation>
<role><roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal"><namePart type="given">KAYSH.</namePart>
<namePart type="family">KAIDBEY</namePart>
<affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</affiliation>
<role><roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal"><namePart type="given">P.C.</namePart>
<namePart type="family">ATKINS</namePart>
<affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</affiliation>
<role><roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal"><namePart type="given">B.</namePart>
<namePart type="family">ZWEIMAN</namePart>
<affiliation>The Department of Dermatology and the Department of Medicine, Allergy and Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, U.S.A.</affiliation>
<role><roleTerm type="text">author</roleTerm>
</role>
</name>
<typeOfResource>text</typeOfResource>
<genre type="article" displayLabel="article"></genre>
<originInfo><publisher>Blackwell Publishing Ltd</publisher>
<place><placeTerm type="text">Oxford, UK</placeTerm>
</place>
<dateIssued encoding="w3cdtf">1984-03</dateIssued>
<edition>Accepted for publication 30 August 1983</edition>
<copyrightDate encoding="w3cdtf">1984</copyrightDate>
</originInfo>
<language><languageTerm type="code" authority="rfc3066">en</languageTerm>
<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
</language>
<physicalDescription><internetMediaType>text/html</internetMediaType>
<extent unit="references">12</extent>
</physicalDescription>
<abstract lang="en">Tolerance to artificial ultraviolet radiation (UVR) was induced in three patients with solar urticaria by administering graded whole body exposures to long‐wave ultraviolet radiation (UV‐A, 320–400 nm) in a phototherapy cabinet. Plasma histamine levels, mast cell ultrastructure and cutaneous responses to intradermally injected codeine and histamine were examined before and after the induction of tolerance. No evidence of serum complement activation could be demonstrated following exposure of serum samples to UVR in vitro. These studies suggest that the state of tolerance is due neither to mediator (histamine) depletion nor to a systemic effect induced by UV‐A but may be due to an increase in the mast cell degranulation threshold.</abstract>
<relatedItem type="host"><titleInfo><title>British Journal of Dermatology</title>
</titleInfo>
<genre type="Journal">journal</genre>
<identifier type="ISSN">0007-0963</identifier>
<identifier type="eISSN">1365-2133</identifier>
<identifier type="DOI">10.1111/(ISSN)1365-2133</identifier>
<identifier type="PublisherID">BJD</identifier>
<part><date>1984</date>
<detail type="volume"><caption>vol.</caption>
<number>110</number>
</detail>
<detail type="issue"><caption>no.</caption>
<number>3</number>
</detail>
<extent unit="pages"><start>327</start>
<end>338</end>
<total>12</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">28FE249E676DA1AE86729AF76FF96BAA935709A4</identifier>
<identifier type="DOI">10.1111/j.1365-2133.1984.tb04639.x</identifier>
<identifier type="ArticleID">BJD327</identifier>
<recordInfo><recordContentSource>WILEY</recordContentSource>
<recordOrigin>Blackwell Publishing Ltd</recordOrigin>
</recordInfo>
</mods>
</metadata>
<serie></serie>
</istex>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Informatique/explor/ScrumV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002577 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 002577 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Informatique |area= ScrumV1 |flux= Istex |étape= Corpus |type= RBID |clé= ISTEX:28FE249E676DA1AE86729AF76FF96BAA935709A4 |texte= Studies on the mechanism of clinical tolerance in solar urticaria }}
![]() | This area was generated with Dilib version V0.6.39. | ![]() |