Complement Levels in Relation to Certain Antibodies in Polytransfused Thalassaemic Patients
Identifieur interne : 002179 ( Istex/Corpus ); précédent : 002178; suivant : 002180Complement Levels in Relation to Certain Antibodies in Polytransfused Thalassaemic Patients
Auteurs : Joanna Economidou ; C. Pathouli ; S. Hadziyannis ; G. Fostiropoulos ; M. ConstantoulakisSource :
- Vox Sanguinis [ 0042-9007 ] ; 1976-12.
Abstract
Abstract. Polytransfused patients are exposed to a variety of antigenic stimuli which may eventually trigger autoimmune reactions. The relation of scrum complement to the occurrence of various antibodies has been investigated in a group of 75 polytransfused thalassaemic patients. The incidence of the antibodies studied was as follows: anti‐HBs 77%, anti‐Gm 64%, rheumatoid factor 31%, antinuclear 13%, anti‐smooth muscle 47%. Anti‐parietal cell, anti‐thyroid and anti‐kidney were only rarely found and antimitochondrial antibodies were never detected. Total hemolytic complement was low in 6 and incidentally decreased in 21 patients. A positive correlation was found between low serum complement and presence of rheumatoid factor. The high incidence of anti‐smooth muscle antibodies seems to be unrelated to liver disease.
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DOI: 10.1111/j.1423-0410.1976.tb02220.x
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Hadziyannis</name><affiliation><mods:affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</mods:affiliation></affiliation></author><author><name sortKey="Fostiropoulos, G" sort="Fostiropoulos, G" uniqKey="Fostiropoulos G" first="G." last="Fostiropoulos">G. Fostiropoulos</name><affiliation><mods:affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</mods:affiliation></affiliation></author><author><name sortKey="Constantoulakis, M" sort="Constantoulakis, M" uniqKey="Constantoulakis M" first="M." last="Constantoulakis">M. Constantoulakis</name><affiliation><mods:affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:393ADD68804672CC0E2427A1BA93D1641A53C8ED</idno><date when="1976" year="1976">1976</date><idno type="doi">10.1111/j.1423-0410.1976.tb02220.x</idno><idno type="url">https://api.istex.fr/document/393ADD68804672CC0E2427A1BA93D1641A53C8ED/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002179</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Complement Levels in Relation to Certain Antibodies in Polytransfused Thalassaemic Patients</title><author><name sortKey="Economidou, Joanna" sort="Economidou, Joanna" uniqKey="Economidou J" first="Joanna" last="Economidou">Joanna Economidou</name><affiliation><mods:affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</mods:affiliation></affiliation></author><author><name sortKey="Pathouli, C" sort="Pathouli, C" uniqKey="Pathouli C" first="C." last="Pathouli">C. Pathouli</name><affiliation><mods:affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</mods:affiliation></affiliation></author><author><name sortKey="Hadziyannis, S" sort="Hadziyannis, S" uniqKey="Hadziyannis S" first="S." last="Hadziyannis">S. Hadziyannis</name><affiliation><mods:affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</mods:affiliation></affiliation></author><author><name sortKey="Fostiropoulos, G" sort="Fostiropoulos, G" uniqKey="Fostiropoulos G" first="G." last="Fostiropoulos">G. Fostiropoulos</name><affiliation><mods:affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</mods:affiliation></affiliation></author><author><name sortKey="Constantoulakis, M" sort="Constantoulakis, M" uniqKey="Constantoulakis M" first="M." last="Constantoulakis">M. Constantoulakis</name><affiliation><mods:affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Vox Sanguinis</title><idno type="ISSN">0042-9007</idno><idno type="eISSN">1423-0410</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1976-12">1976-12</date><biblScope unit="volume">31</biblScope><biblScope unit="supplement">s1</biblScope><biblScope unit="page" from="32">32</biblScope><biblScope unit="page" to="38">38</biblScope></imprint><idno type="ISSN">0042-9007</idno></series><idno type="istex">393ADD68804672CC0E2427A1BA93D1641A53C8ED</idno><idno type="DOI">10.1111/j.1423-0410.1976.tb02220.x</idno><idno type="ArticleID">VOX2220</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0042-9007</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract. Polytransfused patients are exposed to a variety of antigenic stimuli which may eventually trigger autoimmune reactions. The relation of scrum complement to the occurrence of various antibodies has been investigated in a group of 75 polytransfused thalassaemic patients. The incidence of the antibodies studied was as follows: anti‐HBs 77%, anti‐Gm 64%, rheumatoid factor 31%, antinuclear 13%, anti‐smooth muscle 47%. Anti‐parietal cell, anti‐thyroid and anti‐kidney were only rarely found and antimitochondrial antibodies were never detected. Total hemolytic complement was low in 6 and incidentally decreased in 21 patients. A positive correlation was found between low serum complement and presence of rheumatoid factor. The high incidence of anti‐smooth muscle antibodies seems to be unrelated to liver disease.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Joanna Economidou</name><affiliations><json:string>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</json:string></affiliations></json:item><json:item><name>C. Pathouli</name><affiliations><json:string>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</json:string></affiliations></json:item><json:item><name>S. Hadziyannis</name><affiliations><json:string>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</json:string></affiliations></json:item><json:item><name>G. Fostiropoulos</name><affiliations><json:string>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</json:string></affiliations></json:item><json:item><name>M. Constantoulakis</name><affiliations><json:string>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</json:string></affiliations></json:item></author><articleId><json:string>VOX2220</json:string></articleId><language><json:string>eng</json:string></language><abstract>Abstract. Polytransfused patients are exposed to a variety of antigenic stimuli which may eventually trigger autoimmune reactions. The relation of scrum complement to the occurrence of various antibodies has been investigated in a group of 75 polytransfused thalassaemic patients. The incidence of the antibodies studied was as follows: anti‐HBs 77%, anti‐Gm 64%, rheumatoid factor 31%, antinuclear 13%, anti‐smooth muscle 47%. Anti‐parietal cell, anti‐thyroid and anti‐kidney were only rarely found and antimitochondrial antibodies were never detected. Total hemolytic complement was low in 6 and incidentally decreased in 21 patients. A positive correlation was found between low serum complement and presence of rheumatoid factor. 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Polytransfused patients are exposed to a variety of antigenic stimuli which may eventually trigger autoimmune reactions. The relation of scrum complement to the occurrence of various antibodies has been investigated in a group of 75 polytransfused thalassaemic patients. The incidence of the antibodies studied was as follows: anti‐HBs 77%, anti‐Gm 64%, rheumatoid factor 31%, antinuclear 13%, anti‐smooth muscle 47%. Anti‐parietal cell, anti‐thyroid and anti‐kidney were only rarely found and antimitochondrial antibodies were never detected. Total hemolytic complement was low in 6 and incidentally decreased in 21 patients. A positive correlation was found between low serum complement and presence of rheumatoid factor. 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The relation of scrum complement to the occurrence of various antibodies has been investigated in a group of 75 polytransfused thalassaemic patients. The incidence of the antibodies studied was as follows: anti‐HBs 77%, anti‐Gm 64%, rheumatoid factor 31%, antinuclear 13%, anti‐smooth muscle 47%. Anti‐parietal cell, anti‐thyroid and anti‐kidney were only rarely found and antimitochondrial antibodies were never detected. Total hemolytic complement was low in 6 and incidentally decreased in 21 patients. A positive correlation was found between low serum complement and presence of rheumatoid factor. The high incidence of anti‐smooth muscle antibodies seems to be unrelated to liver disease.</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><label>1</label><p>This work was supported in part by a National Research Institute grant.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Complement Levels in Relation to Certain Antibodies in Polytransfused Thalassaemic Patients</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Complement Levels in Relation to Certain Antibodies in Polytransfused Thalassaemic Patients</title></titleInfo><name type="personal"><namePart type="given">Joanna</namePart><namePart type="family">Economidou</namePart><affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</affiliation><description>Correspondence: Hellenic Red Cross Blood Research Laboratory, 4 Alciviadou Street, (Greece)</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C.</namePart><namePart type="family">Pathouli</namePart><affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S.</namePart><namePart type="family">Hadziyannis</namePart><affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G.</namePart><namePart type="family">Fostiropoulos</namePart><affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Constantoulakis</namePart><affiliation>Hellenic Red Cross Blood Research Laboratory, Athens, and Second Department of Medicine, University of Athens, Athens</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">1976-12</dateIssued><edition>Received: December 12, 1975, accepted: March 9, 1976.</edition><copyrightDate encoding="w3cdtf">1976</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="references">19</extent></physicalDescription><abstract lang="en">Abstract. Polytransfused patients are exposed to a variety of antigenic stimuli which may eventually trigger autoimmune reactions. The relation of scrum complement to the occurrence of various antibodies has been investigated in a group of 75 polytransfused thalassaemic patients. The incidence of the antibodies studied was as follows: anti‐HBs 77%, anti‐Gm 64%, rheumatoid factor 31%, antinuclear 13%, anti‐smooth muscle 47%. Anti‐parietal cell, anti‐thyroid and anti‐kidney were only rarely found and antimitochondrial antibodies were never detected. Total hemolytic complement was low in 6 and incidentally decreased in 21 patients. A positive correlation was found between low serum complement and presence of rheumatoid factor. The high incidence of anti‐smooth muscle antibodies seems to be unrelated to liver disease.</abstract><note type="content">*This work was supported in part by a National Research Institute grant.</note><relatedItem type="host"><titleInfo><title>Vox Sanguinis</title></titleInfo><genre type="Journal">journal</genre><identifier type="ISSN">0042-9007</identifier><identifier type="eISSN">1423-0410</identifier><identifier type="DOI">10.1111/(ISSN)1423-0410</identifier><identifier type="PublisherID">VOX</identifier><part><date>1976</date><detail type="volume"><caption>vol.</caption><number>31</number></detail><detail type="supplement"><caption>Suppl. no.</caption><number>s1</number></detail><extent unit="pages"><start>32</start><end>38</end><total>7</total></extent></part></relatedItem><identifier type="istex">393ADD68804672CC0E2427A1BA93D1641A53C8ED</identifier><identifier type="DOI">10.1111/j.1423-0410.1976.tb02220.x</identifier><identifier type="ArticleID">VOX2220</identifier><accessCondition type="use and reproduction" contentType="copyright">© 1976 Blackwell Publishing Ltd</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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