[A new concept for keratoprosthesis].
Identifieur interne : 002227 ( PubMed/Curation ); précédent : 002226; suivant : 002228[A new concept for keratoprosthesis].
Auteurs : H L KainSource :
- Klinische Monatsblätter für Augenheilkunde [ 0023-2165 ] ; 1990.
English descriptors
- KwdEn :
- Animals, Carbon, Cells, Cultured (pathology), Cornea (blood supply), Cornea (surgery), Corneal Stroma (pathology), Fibroblasts (pathology), Foreign-Body Reaction (pathology), HeLa Cells (pathology), Humans, Microscopy, Electron, Scanning, Neovascularization, Pathologic (pathology), Optics and Photonics, Prostheses and Implants, Prosthesis Design, Rabbits, Silicone Elastomers.
- MESH :
- chemical : Carbon, Silicone Elastomers.
- blood supply : Cornea.
- pathology : Cells, Cultured, Corneal Stroma, Fibroblasts, Foreign-Body Reaction, HeLa Cells, Neovascularization, Pathologic.
- surgery : Cornea.
- Animals, Humans, Microscopy, Electron, Scanning, Optics and Photonics, Prostheses and Implants, Prosthesis Design, Rabbits.
Abstract
Although keratoprosthesis (after Strampelli and Cardona) is successful in selected cases, it remains doubtful whether the apparent problems of these procedures can be solved. The Cardona-Strampelli concept was therefore abandoned; a new design was evolved and new alloplastic materials were used--silicone for the optical zone and carbon fibers for the haptic part of the prosthesis. The interaction of living tissue with these alloplastic materials was investigated in tissue-culture experiments and in vivo, and indicated that the materials had excellent properties for prosthetic purposes. Stable anchorage of the implants was assured by the strong adhesion of the fibroplasts to the carbon fibers. In more than a year of observation no granulomatous reaction was observed. In animal experiments, the special design of the prosthesis-tissue interface prevented epithelial downgrowth, one of the major problems in keratoprosthesis. Moreover, a fluid-tight interaction of the alloplastic material and the tissue was achieved.
DOI: 10.1055/s-2008-1046298
PubMed: 1705299
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H L Kain<affiliation><nlm:affiliation>Universitäts-Augenklinik Basel.</nlm:affiliation><wicri:noCountry code="no comma">Universitäts-Augenklinik Basel.</wicri:noCountry></affiliation>Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[A new concept for keratoprosthesis].</title><author><name sortKey="Kain, H L" sort="Kain, H L" uniqKey="Kain H" first="H L" last="Kain">H L Kain</name><affiliation><nlm:affiliation>Universitäts-Augenklinik Basel.</nlm:affiliation><wicri:noCountry code="no comma">Universitäts-Augenklinik Basel.</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1990">1990</date><idno type="RBID">pubmed:1705299</idno><idno type="pmid">1705299</idno><idno type="doi">10.1055/s-2008-1046298</idno><idno type="wicri:Area/PubMed/Corpus">002227</idno><idno type="wicri:Area/PubMed/Curation">002227</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[A new concept for keratoprosthesis].</title><author><name sortKey="Kain, H L" sort="Kain, H L" uniqKey="Kain H" first="H L" last="Kain">H L Kain</name><affiliation><nlm:affiliation>Universitäts-Augenklinik Basel.</nlm:affiliation><wicri:noCountry code="no comma">Universitäts-Augenklinik Basel.</wicri:noCountry></affiliation></author></analytic><series><title level="j">Klinische Monatsblätter für Augenheilkunde</title><idno type="ISSN">0023-2165</idno><imprint><date when="1990" type="published">1990</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Carbon</term><term>Cells, Cultured (pathology)</term><term>Cornea (blood supply)</term><term>Cornea (surgery)</term><term>Corneal Stroma (pathology)</term><term>Fibroblasts (pathology)</term><term>Foreign-Body Reaction (pathology)</term><term>HeLa Cells (pathology)</term><term>Humans</term><term>Microscopy, Electron, Scanning</term><term>Neovascularization, Pathologic (pathology)</term><term>Optics and Photonics</term><term>Prostheses and Implants</term><term>Prosthesis Design</term><term>Rabbits</term><term>Silicone Elastomers</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Carbon</term><term>Silicone Elastomers</term></keywords><keywords scheme="MESH" qualifier="blood supply" xml:lang="en"><term>Cornea</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Cells, Cultured</term><term>Corneal Stroma</term><term>Fibroblasts</term><term>Foreign-Body Reaction</term><term>HeLa Cells</term><term>Neovascularization, Pathologic</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Cornea</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Humans</term><term>Microscopy, Electron, Scanning</term><term>Optics and Photonics</term><term>Prostheses and Implants</term><term>Prosthesis Design</term><term>Rabbits</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Although keratoprosthesis (after Strampelli and Cardona) is successful in selected cases, it remains doubtful whether the apparent problems of these procedures can be solved. The Cardona-Strampelli concept was therefore abandoned; a new design was evolved and new alloplastic materials were used--silicone for the optical zone and carbon fibers for the haptic part of the prosthesis. The interaction of living tissue with these alloplastic materials was investigated in tissue-culture experiments and in vivo, and indicated that the materials had excellent properties for prosthetic purposes. Stable anchorage of the implants was assured by the strong adhesion of the fibroplasts to the carbon fibers. In more than a year of observation no granulomatous reaction was observed. In animal experiments, the special design of the prosthesis-tissue interface prevented epithelial downgrowth, one of the major problems in keratoprosthesis. Moreover, a fluid-tight interaction of the alloplastic material and the tissue was achieved.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">1705299</PMID><DateCreated><Year>1991</Year><Month>04</Month><Day>01</Day></DateCreated><DateCompleted><Year>1991</Year><Month>04</Month><Day>01</Day></DateCompleted><DateRevised><Year>2009</Year><Month>11</Month><Day>11</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0023-2165</ISSN><JournalIssue CitedMedium="Print"><Volume>197</Volume><Issue>5</Issue><PubDate><Year>1990</Year><Month>Nov</Month></PubDate></JournalIssue><Title>Klinische Monatsblätter für Augenheilkunde</Title><ISOAbbreviation>Klin Monbl Augenheilkd</ISOAbbreviation></Journal><ArticleTitle>[A new concept for keratoprosthesis].</ArticleTitle><Pagination><MedlinePgn>386-92</MedlinePgn></Pagination><Abstract><AbstractText>Although keratoprosthesis (after Strampelli and Cardona) is successful in selected cases, it remains doubtful whether the apparent problems of these procedures can be solved. The Cardona-Strampelli concept was therefore abandoned; a new design was evolved and new alloplastic materials were used--silicone for the optical zone and carbon fibers for the haptic part of the prosthesis. The interaction of living tissue with these alloplastic materials was investigated in tissue-culture experiments and in vivo, and indicated that the materials had excellent properties for prosthetic purposes. Stable anchorage of the implants was assured by the strong adhesion of the fibroplasts to the carbon fibers. In more than a year of observation no granulomatous reaction was observed. In animal experiments, the special design of the prosthesis-tissue interface prevented epithelial downgrowth, one of the major problems in keratoprosthesis. Moreover, a fluid-tight interaction of the alloplastic material and the tissue was achieved.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kain</LastName><ForeName>H L</ForeName><Initials>HL</Initials><AffiliationInfo><Affiliation>Universitäts-Augenklinik Basel.</Affiliation></AffiliationInfo></Author></AuthorList><Language>ger</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><VernacularTitle>Ein neues Konzept zur Keratoprothese.</VernacularTitle></Article><MedlineJournalInfo><Country>GERMANY</Country><MedlineTA>Klin Monbl Augenheilkd</MedlineTA><NlmUniqueID>0014133</NlmUniqueID><ISSNLinking>0023-2165</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012826">Silicone Elastomers</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C016482">carbon fiber</NameOfSubstance></Chemical><Chemical><RegistryNumber>7440-44-0</RegistryNumber><NameOfSubstance UI="D002244">Carbon</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000818">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D002244">Carbon</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D002478">Cells, Cultured</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D003315">Cornea</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000098">blood supply</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000601">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D003319">Corneal Stroma</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005347">Fibroblasts</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005549">Foreign-Body Reaction</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006367">HeLa Cells</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008855">Microscopy, Electron, Scanning</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009389">Neovascularization, Pathologic</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D055095">Optics and Photonics</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D019736">Prostheses and Implants</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011474">Prosthesis Design</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011817">Rabbits</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D012826">Silicone Elastomers</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1990</Year><Month>11</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1990</Year><Month>11</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1990</Year><Month>11</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">1705299</ArticleId><ArticleId IdType="doi">10.1055/s-2008-1046298</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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