Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease.
Identifieur interne : 003302 ( PubMed/Checkpoint ); précédent : 003301; suivant : 003303Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease.
Auteurs : Helena Gylling [Finlande] ; Jogchum Plat [Pays-Bas] ; Stephen Turley [États-Unis] ; Henry N. Ginsberg [États-Unis] ; Lars Elleg Rd [Suède] ; Wendy Jessup [Australie] ; Peter J. Jones [Canada] ; Dieter Lütjohann [Allemagne] ; Winfried Maerz [Autriche] ; Luis Masana [Espagne] ; Günther Silbernagel [Suisse] ; Bart Staels [France] ; Jan Borén [Suède] ; Alberico L. Catapano [Italie] ; Guy De Backer [Belgique] ; John Deanfield [Royaume-Uni] ; Olivier S. Descamps [Belgique] ; Petri T. Kovanen [Finlande] ; Gabriele Riccardi [Italie] ; Lale Tokgözoglu [Turquie] ; M John Chapman [France]Source :
- Atherosclerosis [ 1879-1484 ] ; 2014.
Descripteurs français
- KwdFr :
- Animaux, Anticholestérolémiants (usage thérapeutique), Cholestérol (métabolisme), Cholestérol (sang), Cholestérol LDL (sang), Dyslipidémies (), Humains, Inflammation (traitement médicamenteux), Lipides (sang), Maladies cardiovasculaires (), Maladies cardiovasculaires (sang), Phytostérols (usage thérapeutique), Sitostérol (usage thérapeutique), Triglycéride (sang).
- MESH :
- métabolisme : Cholestérol.
- sang : Cholestérol, Cholestérol LDL, Lipides, Maladies cardiovasculaires, Triglycéride.
- traitement médicamenteux : Inflammation.
- usage thérapeutique : Anticholestérolémiants, Phytostérols, Sitostérol.
- Animaux, Dyslipidémies, Humains, Maladies cardiovasculaires.
English descriptors
- KwdEn :
- Animals, Anticholesteremic Agents (therapeutic use), Cardiovascular Diseases (blood), Cardiovascular Diseases (prevention & control), Cardiovascular Diseases (therapy), Cholesterol (blood), Cholesterol (metabolism), Cholesterol, LDL (blood), Dyslipidemias (therapy), Humans, Inflammation (drug therapy), Lipids (blood), Phytosterols (therapeutic use), Sitosterols (therapeutic use), Triglycerides (blood).
- MESH :
- chemical , blood : Cholesterol, Cholesterol, LDL, Lipids, Triglycerides.
- chemical , metabolism : Cholesterol.
- chemical , therapeutic use : Anticholesteremic Agents, Phytosterols, Sitosterols.
- blood : Cardiovascular Diseases.
- drug therapy : Inflammation.
- prevention & control : Cardiovascular Diseases.
- therapy : Cardiovascular Diseases, Dyslipidemias.
- Animals, Humans.
Abstract
This EAS Consensus Panel critically appraised evidence relevant to the benefit to risk relationship of functional foods with added plant sterols and/or plant stanols, as components of a healthy lifestyle, to reduce plasma low-density lipoprotein-cholesterol (LDL-C) levels, and thereby lower cardiovascular risk.
DOI: 10.1016/j.atherosclerosis.2013.11.043
PubMed: 24468148
Affiliations:
- Allemagne, Australie, Autriche, Belgique, Canada, Espagne, Finlande, France, Italie, Pays-Bas, Royaume-Uni, Suisse, Suède, Turquie, États-Unis
- Angleterre, Canton de Berne, Grand Londres, Hauts-de-France, Manitoba, Nord-Pas-de-Calais, Nouvelle-Galles du Sud, Texas, Uusimaa, État de New York, Île-de-France
- Berne, Dallas, Helsinki, Lille, Londres, New York, Paris, Sydney, Winnipeg
- University College de Londres, Université Columbia, Université d'Helsinki, Université de Berne, Université du Manitoba
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:24468148Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease.</title><author><name sortKey="Gylling, Helena" sort="Gylling, Helena" uniqKey="Gylling H" first="Helena" last="Gylling">Helena Gylling</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine, Division of Internal Medicine, University of Helsinki, Biomedicum Helsinki, Finland. Electronic address: Helena.Gylling@hus.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, Division of Internal Medicine, University of Helsinki, Biomedicum Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Plat, Jogchum" sort="Plat, Jogchum" uniqKey="Plat J" first="Jogchum" last="Plat">Jogchum Plat</name><affiliation wicri:level="1"><nlm:affiliation>Department of Human Biology, Maastricht University, The Netherlands. Electronic address: j.plat@maastrichtuniversity.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Biology, Maastricht University</wicri:regionArea><wicri:noRegion>Maastricht University</wicri:noRegion></affiliation></author><author><name sortKey="Turley, Stephen" sort="Turley, Stephen" uniqKey="Turley S" first="Stephen" last="Turley">Stephen Turley</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine, UT Southwestern Medical Center, Dallas, USA. Electronic address: Stephen.Turley@UTSouthwestern.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Internal Medicine, UT Southwestern Medical Center, Dallas</wicri:regionArea><placeName><settlement type="city">Dallas</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Ginsberg, Henry N" sort="Ginsberg, Henry N" uniqKey="Ginsberg H" first="Henry N" last="Ginsberg">Henry N. Ginsberg</name><affiliation wicri:level="4"><nlm:affiliation>Irving Institute for Clinical and Translational Research, Columbia University, New York, USA. Electronic address: hng1@columbia.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Irving Institute for Clinical and Translational Research, Columbia University, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Elleg Rd, Lars" sort="Elleg Rd, Lars" uniqKey="Elleg Rd L" first="Lars" last="Elleg Rd">Lars Elleg Rd</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy at University of Gothenburg, Sweden. Electronic address: lasse.ellegard@nutrition.gu.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy at University of Gothenburg</wicri:regionArea><wicri:noRegion>Sahlgrenska Academy at University of Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Jessup, Wendy" sort="Jessup, Wendy" uniqKey="Jessup W" first="Wendy" last="Jessup">Wendy Jessup</name><affiliation wicri:level="3"><nlm:affiliation>ANZAC Research Institute, Concord Hospital, Sydney, Australia. Electronic address: wendy.jessup@gmail.com.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>ANZAC Research Institute, Concord Hospital, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Jones, Peter J" sort="Jones, Peter J" uniqKey="Jones P" first="Peter J" last="Jones">Peter J. Jones</name><affiliation wicri:level="4"><nlm:affiliation>Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, Canada. Electronic address: Peter.Jones@umanitoba.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg</wicri:regionArea><orgName type="university">Université du Manitoba</orgName><placeName><settlement type="city">Winnipeg</settlement><region type="state">Manitoba</region></placeName></affiliation></author><author><name sortKey="Lutjohann, Dieter" sort="Lutjohann, Dieter" uniqKey="Lutjohann D" first="Dieter" last="Lütjohann">Dieter Lütjohann</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Clinical Pharmacology, University Clinics Bonn, Germany. Electronic address: Dieter.Luetjohann@ukb.uni-bonn.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Clinical Pharmacology, University Clinics Bonn</wicri:regionArea><wicri:noRegion>University Clinics Bonn</wicri:noRegion><wicri:noRegion>University Clinics Bonn</wicri:noRegion><wicri:noRegion>University Clinics Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Maerz, Winfried" sort="Maerz, Winfried" uniqKey="Maerz W" first="Winfried" last="Maerz">Winfried Maerz</name><affiliation wicri:level="1"><nlm:affiliation>Synlab Academy, Synlab LLC, Mannheim Center of Laboratory Diagnostics, Heidelberg, Germany; Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty Mannheim, University of Heidelberg, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Austria. Electronic address: Winfried.Maerz@synlab.com.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Synlab Academy, Synlab LLC, Mannheim Center of Laboratory Diagnostics, Heidelberg, Germany; Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty Mannheim, University of Heidelberg, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz</wicri:regionArea><wicri:noRegion>Medical University of Graz</wicri:noRegion></affiliation></author><author><name sortKey="Masana, Luis" sort="Masana, Luis" uniqKey="Masana L" first="Luis" last="Masana">Luis Masana</name><affiliation wicri:level="1"><nlm:affiliation>Vascular Medicine and Metabolism Unit, University Hospital Sant Joan, IISPV, CIBERDEM, Rovira and Virgili University, Reus, Spain. Electronic address: luis.masana@urv.cat.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Vascular Medicine and Metabolism Unit, University Hospital Sant Joan, IISPV, CIBERDEM, Rovira and Virgili University, Reus</wicri:regionArea><wicri:noRegion>Reus</wicri:noRegion></affiliation></author><author><name sortKey="Silbernagel, Gunther" sort="Silbernagel, Gunther" uniqKey="Silbernagel G" first="Günther" last="Silbernagel">Günther Silbernagel</name><affiliation wicri:level="4"><nlm:affiliation>Department of Angiology, Swiss Cardiovascular Center, Inselspital, University of Bern, Switzerland. Electronic address: guenther.silbernagel@yahoo.com.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Angiology, Swiss Cardiovascular Center, Inselspital, University of Bern</wicri:regionArea><placeName><settlement type="city">Berne</settlement><region nuts="3" type="region">Canton de Berne</region></placeName><orgName type="university">Université de Berne</orgName></affiliation></author><author><name sortKey="Staels, Bart" sort="Staels, Bart" uniqKey="Staels B" first="Bart" last="Staels">Bart Staels</name><affiliation wicri:level="3"><nlm:affiliation>Faculty of Pharmacy, University of Lille 2, Lille, France. Electronic address: Bart.Staels@pasteur-lille.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Faculty of Pharmacy, University of Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Boren, Jan" sort="Boren, Jan" uniqKey="Boren J" first="Jan" last="Borén">Jan Borén</name><affiliation wicri:level="1"><nlm:affiliation>Strategic Research Center, Sahlgrenska Center for Cardiovascular and Metabolic Research (CMR), University of Gothenburg, Sweden. Electronic address: Jan.Boren@wlab.gu.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Strategic Research Center, Sahlgrenska Center for Cardiovascular and Metabolic Research (CMR), University of Gothenburg</wicri:regionArea><wicri:noRegion>University of Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Catapano, Alberico L" sort="Catapano, Alberico L" uniqKey="Catapano A" first="Alberico L" last="Catapano">Alberico L. Catapano</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacological and Biomolecular Sciences, University of Milan, Italy; Multimedica IRCSS Milano, Italy. Electronic address: alberico.catapano@unimi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Pharmacological and Biomolecular Sciences, University of Milan, Italy; Multimedica IRCSS Milano</wicri:regionArea><wicri:noRegion>Italy; Multimedica IRCSS Milano</wicri:noRegion></affiliation></author><author><name sortKey="De Backer, Guy" sort="De Backer, Guy" uniqKey="De Backer G" first="Guy" last="De Backer">Guy De Backer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, University Hospital Ghent, Ghent, Belgium. Electronic address: guy.debacker@ugent.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Public Health, University Hospital Ghent, Ghent</wicri:regionArea><wicri:noRegion>Ghent</wicri:noRegion></affiliation></author><author><name sortKey="Deanfield, John" sort="Deanfield, John" uniqKey="Deanfield J" first="John" last="Deanfield">John Deanfield</name><affiliation wicri:level="4"><nlm:affiliation>National Centre for Cardiovascular Prevention and Outcomes, University College London, UK. Electronic address: john.deanfield@gmail.com.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Centre for Cardiovascular Prevention and Outcomes, University College London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Descamps, Olivier S" sort="Descamps, Olivier S" uniqKey="Descamps O" first="Olivier S" last="Descamps">Olivier S. Descamps</name><affiliation wicri:level="1"><nlm:affiliation>Lipid Clinic, Hopital de Jolimont, Haine-Saint-Paul, Belgium. Electronic address: olivierdescamps@hotmail.com.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Lipid Clinic, Hopital de Jolimont, Haine-Saint-Paul</wicri:regionArea><wicri:noRegion>Haine-Saint-Paul</wicri:noRegion></affiliation></author><author><name sortKey="Kovanen, Petri T" sort="Kovanen, Petri T" uniqKey="Kovanen P" first="Petri T" last="Kovanen">Petri T. Kovanen</name><affiliation wicri:level="1"><nlm:affiliation>Wihuri Research Institute, Helsinki, Finland. Electronic address: Petri.Kovanen@wri.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Wihuri Research Institute, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Riccardi, Gabriele" sort="Riccardi, Gabriele" uniqKey="Riccardi G" first="Gabriele" last="Riccardi">Gabriele Riccardi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy. Electronic address: riccardi@unina.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical and Experimental Medicine, Federico II University, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Tokgozoglu, Lale" sort="Tokgozoglu, Lale" uniqKey="Tokgozoglu L" first="Lale" last="Tokgözoglu">Lale Tokgözoglu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Hacettepe University, Ankara, Turkey. Electronic address: lalet@hacettepe.edu.tr.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Cardiology, Hacettepe University, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author><author><name sortKey="Chapman, M John" sort="Chapman, M John" uniqKey="Chapman M" first="M John" last="Chapman">M John Chapman</name><affiliation wicri:level="3"><nlm:affiliation>University of Pierre and Marie Curie, Paris, France; Dyslipidaemia and Atherosclerosis Research Unit, INSERM U939, Pitié-Salpetriere University Hospital, Paris, France. Electronic address: john.chapman@upmc.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University of Pierre and Marie Curie, Paris, France; Dyslipidaemia and Atherosclerosis Research Unit, INSERM U939, Pitié-Salpetriere University Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24468148</idno><idno type="pmid">24468148</idno><idno type="doi">10.1016/j.atherosclerosis.2013.11.043</idno><idno type="wicri:Area/PubMed/Corpus">003961</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003961</idno><idno type="wicri:Area/PubMed/Curation">003846</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003846</idno><idno type="wicri:Area/PubMed/Checkpoint">003846</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">003846</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease.</title><author><name sortKey="Gylling, Helena" sort="Gylling, Helena" uniqKey="Gylling H" first="Helena" last="Gylling">Helena Gylling</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine, Division of Internal Medicine, University of Helsinki, Biomedicum Helsinki, Finland. Electronic address: Helena.Gylling@hus.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, Division of Internal Medicine, University of Helsinki, Biomedicum Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Plat, Jogchum" sort="Plat, Jogchum" uniqKey="Plat J" first="Jogchum" last="Plat">Jogchum Plat</name><affiliation wicri:level="1"><nlm:affiliation>Department of Human Biology, Maastricht University, The Netherlands. Electronic address: j.plat@maastrichtuniversity.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Biology, Maastricht University</wicri:regionArea><wicri:noRegion>Maastricht University</wicri:noRegion></affiliation></author><author><name sortKey="Turley, Stephen" sort="Turley, Stephen" uniqKey="Turley S" first="Stephen" last="Turley">Stephen Turley</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine, UT Southwestern Medical Center, Dallas, USA. Electronic address: Stephen.Turley@UTSouthwestern.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Internal Medicine, UT Southwestern Medical Center, Dallas</wicri:regionArea><placeName><settlement type="city">Dallas</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Ginsberg, Henry N" sort="Ginsberg, Henry N" uniqKey="Ginsberg H" first="Henry N" last="Ginsberg">Henry N. Ginsberg</name><affiliation wicri:level="4"><nlm:affiliation>Irving Institute for Clinical and Translational Research, Columbia University, New York, USA. Electronic address: hng1@columbia.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Irving Institute for Clinical and Translational Research, Columbia University, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Elleg Rd, Lars" sort="Elleg Rd, Lars" uniqKey="Elleg Rd L" first="Lars" last="Elleg Rd">Lars Elleg Rd</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy at University of Gothenburg, Sweden. Electronic address: lasse.ellegard@nutrition.gu.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy at University of Gothenburg</wicri:regionArea><wicri:noRegion>Sahlgrenska Academy at University of Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Jessup, Wendy" sort="Jessup, Wendy" uniqKey="Jessup W" first="Wendy" last="Jessup">Wendy Jessup</name><affiliation wicri:level="3"><nlm:affiliation>ANZAC Research Institute, Concord Hospital, Sydney, Australia. Electronic address: wendy.jessup@gmail.com.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>ANZAC Research Institute, Concord Hospital, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Jones, Peter J" sort="Jones, Peter J" uniqKey="Jones P" first="Peter J" last="Jones">Peter J. Jones</name><affiliation wicri:level="4"><nlm:affiliation>Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, Canada. Electronic address: Peter.Jones@umanitoba.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg</wicri:regionArea><orgName type="university">Université du Manitoba</orgName><placeName><settlement type="city">Winnipeg</settlement><region type="state">Manitoba</region></placeName></affiliation></author><author><name sortKey="Lutjohann, Dieter" sort="Lutjohann, Dieter" uniqKey="Lutjohann D" first="Dieter" last="Lütjohann">Dieter Lütjohann</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Chemistry and Clinical Pharmacology, University Clinics Bonn, Germany. Electronic address: Dieter.Luetjohann@ukb.uni-bonn.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Clinical Pharmacology, University Clinics Bonn</wicri:regionArea><wicri:noRegion>University Clinics Bonn</wicri:noRegion><wicri:noRegion>University Clinics Bonn</wicri:noRegion><wicri:noRegion>University Clinics Bonn</wicri:noRegion></affiliation></author><author><name sortKey="Maerz, Winfried" sort="Maerz, Winfried" uniqKey="Maerz W" first="Winfried" last="Maerz">Winfried Maerz</name><affiliation wicri:level="1"><nlm:affiliation>Synlab Academy, Synlab LLC, Mannheim Center of Laboratory Diagnostics, Heidelberg, Germany; Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty Mannheim, University of Heidelberg, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Austria. Electronic address: Winfried.Maerz@synlab.com.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Synlab Academy, Synlab LLC, Mannheim Center of Laboratory Diagnostics, Heidelberg, Germany; Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty Mannheim, University of Heidelberg, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz</wicri:regionArea><wicri:noRegion>Medical University of Graz</wicri:noRegion></affiliation></author><author><name sortKey="Masana, Luis" sort="Masana, Luis" uniqKey="Masana L" first="Luis" last="Masana">Luis Masana</name><affiliation wicri:level="1"><nlm:affiliation>Vascular Medicine and Metabolism Unit, University Hospital Sant Joan, IISPV, CIBERDEM, Rovira and Virgili University, Reus, Spain. Electronic address: luis.masana@urv.cat.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Vascular Medicine and Metabolism Unit, University Hospital Sant Joan, IISPV, CIBERDEM, Rovira and Virgili University, Reus</wicri:regionArea><wicri:noRegion>Reus</wicri:noRegion></affiliation></author><author><name sortKey="Silbernagel, Gunther" sort="Silbernagel, Gunther" uniqKey="Silbernagel G" first="Günther" last="Silbernagel">Günther Silbernagel</name><affiliation wicri:level="4"><nlm:affiliation>Department of Angiology, Swiss Cardiovascular Center, Inselspital, University of Bern, Switzerland. Electronic address: guenther.silbernagel@yahoo.com.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Angiology, Swiss Cardiovascular Center, Inselspital, University of Bern</wicri:regionArea><placeName><settlement type="city">Berne</settlement><region nuts="3" type="region">Canton de Berne</region></placeName><orgName type="university">Université de Berne</orgName></affiliation></author><author><name sortKey="Staels, Bart" sort="Staels, Bart" uniqKey="Staels B" first="Bart" last="Staels">Bart Staels</name><affiliation wicri:level="3"><nlm:affiliation>Faculty of Pharmacy, University of Lille 2, Lille, France. Electronic address: Bart.Staels@pasteur-lille.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Faculty of Pharmacy, University of Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Boren, Jan" sort="Boren, Jan" uniqKey="Boren J" first="Jan" last="Borén">Jan Borén</name><affiliation wicri:level="1"><nlm:affiliation>Strategic Research Center, Sahlgrenska Center for Cardiovascular and Metabolic Research (CMR), University of Gothenburg, Sweden. Electronic address: Jan.Boren@wlab.gu.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Strategic Research Center, Sahlgrenska Center for Cardiovascular and Metabolic Research (CMR), University of Gothenburg</wicri:regionArea><wicri:noRegion>University of Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Catapano, Alberico L" sort="Catapano, Alberico L" uniqKey="Catapano A" first="Alberico L" last="Catapano">Alberico L. Catapano</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacological and Biomolecular Sciences, University of Milan, Italy; Multimedica IRCSS Milano, Italy. Electronic address: alberico.catapano@unimi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Pharmacological and Biomolecular Sciences, University of Milan, Italy; Multimedica IRCSS Milano</wicri:regionArea><wicri:noRegion>Italy; Multimedica IRCSS Milano</wicri:noRegion></affiliation></author><author><name sortKey="De Backer, Guy" sort="De Backer, Guy" uniqKey="De Backer G" first="Guy" last="De Backer">Guy De Backer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health, University Hospital Ghent, Ghent, Belgium. Electronic address: guy.debacker@ugent.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Public Health, University Hospital Ghent, Ghent</wicri:regionArea><wicri:noRegion>Ghent</wicri:noRegion></affiliation></author><author><name sortKey="Deanfield, John" sort="Deanfield, John" uniqKey="Deanfield J" first="John" last="Deanfield">John Deanfield</name><affiliation wicri:level="4"><nlm:affiliation>National Centre for Cardiovascular Prevention and Outcomes, University College London, UK. Electronic address: john.deanfield@gmail.com.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Centre for Cardiovascular Prevention and Outcomes, University College London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Descamps, Olivier S" sort="Descamps, Olivier S" uniqKey="Descamps O" first="Olivier S" last="Descamps">Olivier S. Descamps</name><affiliation wicri:level="1"><nlm:affiliation>Lipid Clinic, Hopital de Jolimont, Haine-Saint-Paul, Belgium. Electronic address: olivierdescamps@hotmail.com.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Lipid Clinic, Hopital de Jolimont, Haine-Saint-Paul</wicri:regionArea><wicri:noRegion>Haine-Saint-Paul</wicri:noRegion></affiliation></author><author><name sortKey="Kovanen, Petri T" sort="Kovanen, Petri T" uniqKey="Kovanen P" first="Petri T" last="Kovanen">Petri T. Kovanen</name><affiliation wicri:level="1"><nlm:affiliation>Wihuri Research Institute, Helsinki, Finland. Electronic address: Petri.Kovanen@wri.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Wihuri Research Institute, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Riccardi, Gabriele" sort="Riccardi, Gabriele" uniqKey="Riccardi G" first="Gabriele" last="Riccardi">Gabriele Riccardi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy. Electronic address: riccardi@unina.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical and Experimental Medicine, Federico II University, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Tokgozoglu, Lale" sort="Tokgozoglu, Lale" uniqKey="Tokgozoglu L" first="Lale" last="Tokgözoglu">Lale Tokgözoglu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Hacettepe University, Ankara, Turkey. Electronic address: lalet@hacettepe.edu.tr.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Cardiology, Hacettepe University, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author><author><name sortKey="Chapman, M John" sort="Chapman, M John" uniqKey="Chapman M" first="M John" last="Chapman">M John Chapman</name><affiliation wicri:level="3"><nlm:affiliation>University of Pierre and Marie Curie, Paris, France; Dyslipidaemia and Atherosclerosis Research Unit, INSERM U939, Pitié-Salpetriere University Hospital, Paris, France. Electronic address: john.chapman@upmc.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University of Pierre and Marie Curie, Paris, France; Dyslipidaemia and Atherosclerosis Research Unit, INSERM U939, Pitié-Salpetriere University Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></analytic><series><title level="j">Atherosclerosis</title><idno type="eISSN">1879-1484</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Anticholesteremic Agents (therapeutic use)</term><term>Cardiovascular Diseases (blood)</term><term>Cardiovascular Diseases (prevention & control)</term><term>Cardiovascular Diseases (therapy)</term><term>Cholesterol (blood)</term><term>Cholesterol (metabolism)</term><term>Cholesterol, LDL (blood)</term><term>Dyslipidemias (therapy)</term><term>Humans</term><term>Inflammation (drug therapy)</term><term>Lipids (blood)</term><term>Phytosterols (therapeutic use)</term><term>Sitosterols (therapeutic use)</term><term>Triglycerides (blood)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Anticholestérolémiants (usage thérapeutique)</term><term>Cholestérol (métabolisme)</term><term>Cholestérol (sang)</term><term>Cholestérol LDL (sang)</term><term>Dyslipidémies ()</term><term>Humains</term><term>Inflammation (traitement médicamenteux)</term><term>Lipides (sang)</term><term>Maladies cardiovasculaires ()</term><term>Maladies cardiovasculaires (sang)</term><term>Phytostérols (usage thérapeutique)</term><term>Sitostérol (usage thérapeutique)</term><term>Triglycéride (sang)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Cholesterol</term><term>Cholesterol, LDL</term><term>Lipids</term><term>Triglycerides</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Cholesterol</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anticholesteremic Agents</term><term>Phytosterols</term><term>Sitosterols</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Cardiovascular Diseases</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Inflammation</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Cholestérol</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Cardiovascular Diseases</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Cholestérol</term><term>Cholestérol LDL</term><term>Lipides</term><term>Maladies cardiovasculaires</term><term>Triglycéride</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Cardiovascular Diseases</term><term>Dyslipidemias</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Inflammation</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Anticholestérolémiants</term><term>Phytostérols</term><term>Sitostérol</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Dyslipidémies</term><term>Humains</term><term>Maladies cardiovasculaires</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This EAS Consensus Panel critically appraised evidence relevant to the benefit to risk relationship of functional foods with added plant sterols and/or plant stanols, as components of a healthy lifestyle, to reduce plasma low-density lipoprotein-cholesterol (LDL-C) levels, and thereby lower cardiovascular risk.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24468148</PMID><DateCreated><Year>2014</Year><Month>01</Month><Day>28</Day></DateCreated><DateCompleted><Year>2014</Year><Month>09</Month><Day>29</Day></DateCompleted><DateRevised><Year>2014</Year><Month>01</Month><Day>28</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1879-1484</ISSN><JournalIssue CitedMedium="Internet"><Volume>232</Volume><Issue>2</Issue><PubDate><Year>2014</Year><Month>Feb</Month></PubDate></JournalIssue><Title>Atherosclerosis</Title><ISOAbbreviation>Atherosclerosis</ISOAbbreviation></Journal><ArticleTitle>Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease.</ArticleTitle><Pagination><MedlinePgn>346-60</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.atherosclerosis.2013.11.043</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0021-9150(13)00694-1</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">This EAS Consensus Panel critically appraised evidence relevant to the benefit to risk relationship of functional foods with added plant sterols and/or plant stanols, as components of a healthy lifestyle, to reduce plasma low-density lipoprotein-cholesterol (LDL-C) levels, and thereby lower cardiovascular risk.</AbstractText><AbstractText Label="METHODS AND RESULTS" NlmCategory="RESULTS">Plant sterols/stanols (when taken at 2 g/day) cause significant inhibition of cholesterol absorption and lower LDL-C levels by between 8 and 10%. The relative proportions of cholesterol versus sterol/stanol levels are similar in both plasma and tissue, with levels of sterols/stanols being 500-/10,000-fold lower than those of cholesterol, suggesting they are handled similarly to cholesterol in most cells. Despite possible atherogenicity of marked elevations in circulating levels of plant sterols/stanols, protective effects have been observed in some animal models of atherosclerosis. Higher plasma levels of plant sterols/stanols associated with intakes of 2 g/day in man have not been linked to adverse effects on health in long-term human studies. Importantly, at this dose, plant sterol/stanol-mediated LDL-C lowering is additive to that of statins in dyslipidaemic subjects, equivalent to doubling the dose of statin. The reported 6-9% lowering of plasma triglyceride by 2 g/day in hypertriglyceridaemic patients warrants further evaluation.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Based on LDL-C lowering and the absence of adverse signals, this EAS Consensus Panel concludes that functional foods with plant sterols/stanols may be considered 1) in individuals with high cholesterol levels at intermediate or low global cardiovascular risk who do not qualify for pharmacotherapy, 2) as an adjunct to pharmacologic therapy in high and very high risk patients who fail to achieve LDL-C targets on statins or are statin- intolerant, 3) and in adults and children (>6 years) with familial hypercholesterolaemia, in line with current guidance. However, it must be acknowledged that there are no randomised, controlled clinical trial data with hard end-points to establish clinical benefit from the use of plant sterols or plant stanols.</AbstractText><CopyrightInformation>Copyright © 2013 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gylling</LastName><ForeName>Helena</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Medicine, Division of Internal Medicine, University of Helsinki, Biomedicum Helsinki, Finland. Electronic address: Helena.Gylling@hus.fi.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Plat</LastName><ForeName>Jogchum</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Human Biology, Maastricht University, The Netherlands. Electronic address: j.plat@maastrichtuniversity.nl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Turley</LastName><ForeName>Stephen</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, UT Southwestern Medical Center, Dallas, USA. Electronic address: Stephen.Turley@UTSouthwestern.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ginsberg</LastName><ForeName>Henry N</ForeName><Initials>HN</Initials><AffiliationInfo><Affiliation>Irving Institute for Clinical and Translational Research, Columbia University, New York, USA. Electronic address: hng1@columbia.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ellegård</LastName><ForeName>Lars</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy at University of Gothenburg, Sweden. Electronic address: lasse.ellegard@nutrition.gu.se.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jessup</LastName><ForeName>Wendy</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>ANZAC Research Institute, Concord Hospital, Sydney, Australia. Electronic address: wendy.jessup@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jones</LastName><ForeName>Peter J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, Canada. Electronic address: Peter.Jones@umanitoba.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lütjohann</LastName><ForeName>Dieter</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Institute of Clinical Chemistry and Clinical Pharmacology, University Clinics Bonn, Germany. Electronic address: Dieter.Luetjohann@ukb.uni-bonn.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maerz</LastName><ForeName>Winfried</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Synlab Academy, Synlab LLC, Mannheim Center of Laboratory Diagnostics, Heidelberg, Germany; Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty Mannheim, University of Heidelberg, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Austria. Electronic address: Winfried.Maerz@synlab.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Masana</LastName><ForeName>Luis</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Vascular Medicine and Metabolism Unit, University Hospital Sant Joan, IISPV, CIBERDEM, Rovira and Virgili University, Reus, Spain. Electronic address: luis.masana@urv.cat.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Silbernagel</LastName><ForeName>Günther</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Angiology, Swiss Cardiovascular Center, Inselspital, University of Bern, Switzerland. Electronic address: guenther.silbernagel@yahoo.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Staels</LastName><ForeName>Bart</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Faculty of Pharmacy, University of Lille 2, Lille, France. Electronic address: Bart.Staels@pasteur-lille.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Borén</LastName><ForeName>Jan</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Strategic Research Center, Sahlgrenska Center for Cardiovascular and Metabolic Research (CMR), University of Gothenburg, Sweden. Electronic address: Jan.Boren@wlab.gu.se.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Catapano</LastName><ForeName>Alberico L</ForeName><Initials>AL</Initials><AffiliationInfo><Affiliation>Department of Pharmacological and Biomolecular Sciences, University of Milan, Italy; Multimedica IRCSS Milano, Italy. Electronic address: alberico.catapano@unimi.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Backer</LastName><ForeName>Guy</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Public Health, University Hospital Ghent, Ghent, Belgium. Electronic address: guy.debacker@ugent.be.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Deanfield</LastName><ForeName>John</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>National Centre for Cardiovascular Prevention and Outcomes, University College London, UK. Electronic address: john.deanfield@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Descamps</LastName><ForeName>Olivier S</ForeName><Initials>OS</Initials><AffiliationInfo><Affiliation>Lipid Clinic, Hopital de Jolimont, Haine-Saint-Paul, Belgium. Electronic address: olivierdescamps@hotmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kovanen</LastName><ForeName>Petri T</ForeName><Initials>PT</Initials><AffiliationInfo><Affiliation>Wihuri Research Institute, Helsinki, Finland. Electronic address: Petri.Kovanen@wri.fi.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Riccardi</LastName><ForeName>Gabriele</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy. Electronic address: riccardi@unina.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tokgözoglu</LastName><ForeName>Lale</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Hacettepe University, Ankara, Turkey. Electronic address: lalet@hacettepe.edu.tr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chapman</LastName><ForeName>M John</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>University of Pierre and Marie Curie, Paris, France; Dyslipidaemia and Atherosclerosis Research Unit, INSERM U939, Pitié-Salpetriere University Hospital, Paris, France. Electronic address: john.chapman@upmc.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>European Atherosclerosis Society Consensus Panel on Phytosterols</CollectiveName></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>R01HL09610</GrantID><Acronym>HL</Acronym><Agency>NHLBI NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>11</Month><Day>23</Day></ArticleDate></Article><MedlineJournalInfo><Country>Ireland</Country><MedlineTA>Atherosclerosis</MedlineTA><NlmUniqueID>0242543</NlmUniqueID><ISSNLinking>0021-9150</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000924">Anticholesteremic Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008078">Cholesterol, LDL</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008055">Lipids</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010840">Phytosterols</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012855">Sitosterols</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014280">Triglycerides</NameOfSubstance></Chemical><Chemical><RegistryNumber>97C5T2UQ7J</RegistryNumber><NameOfSubstance UI="D002784">Cholesterol</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Atherosclerosis. 2014 Apr;233(2):357-8</RefSource><PMID Version="1">24530762</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000924" MajorTopicYN="N">Anticholesteremic Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002318" MajorTopicYN="N">Cardiovascular Diseases</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002784" MajorTopicYN="N">Cholesterol</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008078" MajorTopicYN="N">Cholesterol, LDL</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D050171" MajorTopicYN="N">Dyslipidemias</DescriptorName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007249" MajorTopicYN="N">Inflammation</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008055" MajorTopicYN="N">Lipids</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010840" MajorTopicYN="N">Phytosterols</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012855" MajorTopicYN="N">Sitosterols</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014280" MajorTopicYN="N">Triglycerides</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Cardiovascular risk</Keyword><Keyword MajorTopicYN="N">Functional foods with added plant sterols and plant stanols</Keyword><Keyword MajorTopicYN="N">Hypercholesterolaemia</Keyword><Keyword MajorTopicYN="N">Intestinal cholesterol absorption</Keyword><Keyword MajorTopicYN="N">Phytosterols</Keyword><Keyword MajorTopicYN="N">Safety</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>11</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>11</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>1</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>1</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>9</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24468148</ArticleId><ArticleId IdType="pii">S0021-9150(13)00694-1</ArticleId><ArticleId IdType="doi">10.1016/j.atherosclerosis.2013.11.043</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Belgique</li><li>Canada</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Italie</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suisse</li><li>Suède</li><li>Turquie</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Canton de Berne</li><li>Grand Londres</li><li>Hauts-de-France</li><li>Manitoba</li><li>Nord-Pas-de-Calais</li><li>Nouvelle-Galles du Sud</li><li>Texas</li><li>Uusimaa</li><li>État de New York</li><li>Île-de-France</li></region><settlement><li>Berne</li><li>Dallas</li><li>Helsinki</li><li>Lille</li><li>Londres</li><li>New York</li><li>Paris</li><li>Sydney</li><li>Winnipeg</li></settlement><orgName><li>University College de Londres</li><li>Université Columbia</li><li>Université d'Helsinki</li><li>Université de Berne</li><li>Université du Manitoba</li></orgName></list><tree><country name="Finlande"><region name="Uusimaa"><name sortKey="Gylling, Helena" sort="Gylling, Helena" uniqKey="Gylling H" first="Helena" last="Gylling">Helena Gylling</name></region><name sortKey="Kovanen, Petri T" sort="Kovanen, Petri T" uniqKey="Kovanen P" first="Petri T" last="Kovanen">Petri T. Kovanen</name></country><country name="Pays-Bas"><noRegion><name sortKey="Plat, Jogchum" sort="Plat, Jogchum" uniqKey="Plat J" first="Jogchum" last="Plat">Jogchum Plat</name></noRegion></country><country name="États-Unis"><region name="Texas"><name sortKey="Turley, Stephen" sort="Turley, Stephen" uniqKey="Turley S" first="Stephen" last="Turley">Stephen Turley</name></region><name sortKey="Ginsberg, Henry N" sort="Ginsberg, Henry N" uniqKey="Ginsberg H" first="Henry N" last="Ginsberg">Henry N. Ginsberg</name></country><country name="Suède"><noRegion><name sortKey="Elleg Rd, Lars" sort="Elleg Rd, Lars" uniqKey="Elleg Rd L" first="Lars" last="Elleg Rd">Lars Elleg Rd</name></noRegion><name sortKey="Boren, Jan" sort="Boren, Jan" uniqKey="Boren J" first="Jan" last="Borén">Jan Borén</name></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Jessup, Wendy" sort="Jessup, Wendy" uniqKey="Jessup W" first="Wendy" last="Jessup">Wendy Jessup</name></region></country><country name="Canada"><region name="Manitoba"><name sortKey="Jones, Peter J" sort="Jones, Peter J" uniqKey="Jones P" first="Peter J" last="Jones">Peter J. Jones</name></region></country><country name="Allemagne"><noRegion><name sortKey="Lutjohann, Dieter" sort="Lutjohann, Dieter" uniqKey="Lutjohann D" first="Dieter" last="Lütjohann">Dieter Lütjohann</name></noRegion></country><country name="Autriche"><noRegion><name sortKey="Maerz, Winfried" sort="Maerz, Winfried" uniqKey="Maerz W" first="Winfried" last="Maerz">Winfried Maerz</name></noRegion></country><country name="Espagne"><noRegion><name sortKey="Masana, Luis" sort="Masana, Luis" uniqKey="Masana L" first="Luis" last="Masana">Luis Masana</name></noRegion></country><country name="Suisse"><region name="Canton de Berne"><name sortKey="Silbernagel, Gunther" sort="Silbernagel, Gunther" uniqKey="Silbernagel G" first="Günther" last="Silbernagel">Günther Silbernagel</name></region></country><country name="France"><region name="Hauts-de-France"><name sortKey="Staels, Bart" sort="Staels, Bart" uniqKey="Staels B" first="Bart" last="Staels">Bart Staels</name></region><name sortKey="Chapman, M John" sort="Chapman, M John" uniqKey="Chapman M" first="M John" last="Chapman">M John Chapman</name></country><country name="Italie"><noRegion><name sortKey="Catapano, Alberico L" sort="Catapano, Alberico L" uniqKey="Catapano A" first="Alberico L" last="Catapano">Alberico L. Catapano</name></noRegion><name sortKey="Riccardi, Gabriele" sort="Riccardi, Gabriele" uniqKey="Riccardi G" first="Gabriele" last="Riccardi">Gabriele Riccardi</name></country><country name="Belgique"><noRegion><name sortKey="De Backer, Guy" sort="De Backer, Guy" uniqKey="De Backer G" first="Guy" last="De Backer">Guy De Backer</name></noRegion><name sortKey="Descamps, Olivier S" sort="Descamps, Olivier S" uniqKey="Descamps O" first="Olivier S" last="Descamps">Olivier S. Descamps</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Deanfield, John" sort="Deanfield, John" uniqKey="Deanfield J" first="John" last="Deanfield">John Deanfield</name></region></country><country name="Turquie"><noRegion><name sortKey="Tokgozoglu, Lale" sort="Tokgozoglu, Lale" uniqKey="Tokgozoglu L" first="Lale" last="Tokgözoglu">Lale Tokgözoglu</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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