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Staphylococcus aureus endocarditis : A consequence of medical progress

Identifieur interne : 00A432 ( Main/Exploration ); précédent : 00A431; suivant : 00A433

Staphylococcus aureus endocarditis : A consequence of medical progress

Auteurs : Vance G. Jr Fowler [États-Unis] ; Jose M. Miro [Espagne] ; Bruno Hoen [France] ; Christopher H. Cabell [États-Unis] ; Elias Abrutyn [États-Unis] ; Ethan Rubinstein [Israël] ; Llb G. Ralph Corey [États-Unis] ; Denis Spelman [Australie] ; Suzanne F. Bradley [États-Unis] ; Bruno Barsic [Croatie] ; Paul A. Pappas [États-Unis] ; Kevin J. Anstrom [États-Unis] ; Dannah Wray [États-Unis] ; Claudio Q. Fortes [Brésil] ; Ignasi Anguera [Espagne] ; Eugene Athan [Australie] ; Philip Jones [Australie] ; Jan T. M. Van Der Meer [Pays-Bas] ; Tom S. J. Elliott [Royaume-Uni] ; Donald P. Levine [États-Unis] ; Arnold S. Bayer [États-Unis]

Source :

RBID : Pascal:05-0289831

Descripteurs français

English descriptors

Abstract

Context The global significance of infective endocarditis (IE) caused by Staphylococcus aureus is unknown. Objectives To document the international emergence of health care-associated S aureus IE and methicillin-resistant S aureus (MRSA) IE and to evaluate regional variation in patients with S aureus IE. Design, Setting, and Participants Prospective observational cohort study set in 39 medical centers in 16 countries. Participants were a population of 1779 patients with definite IE as defined by Duke criteria who were enrolled in the International Collaboration on Endocarditis-Prospective Cohort Study from June 2000 to December 2003. Main Outcome Measure In-hospital mortality. Results S aureus was the most common pathogen among the 1779 cases of definite IE in the International Collaboration on Endocarditis Prospective-Cohort Study (558 patients, 31.4%). Health care-associated infection was the most common form of S aureus IE (218 patients, 39.1%), accounting for 25.9% (Australia/New Zealand) to 54.2% (Brazil) of cases. Most patients with health care-associated S aureus I E (131 patients, 60.1 %) acquired the infection outside of the hospital. MRSA IE was more common in the United States (37.2%) and Brazil (37.5%) than in Europe/Middle East (23.7%) and Australia/ New Zealand (15.5%, P<.001). Persistent bacteremia was independently associated with MRSA IE (odds ratio, 6.2; 95% confidence interval, 2.9-13.2). Patients in the United States were most likely to be hemodialysis dependent, to have diabetes, to have a presumed intravascular device source, to receive vancomycin, to be infected with MRSA, and to have persistent bacteremia (P<.001 for all comparisons). Conclusions S aureus is the leading cause of IE in many regions of the world. Characteristics of patients with S aureus IE vary significantly by region. Further studies are required to determine the causes of regional variation.


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Le document en format XML

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<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
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<country>États-Unis</country>
<wicri:noRegion>Duke University Medical Center</wicri:noRegion>
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</author>
<author>
<name sortKey="Wray, Dannah" sort="Wray, Dannah" uniqKey="Wray D" first="Dannah" last="Wray">Dannah Wray</name>
<affiliation wicri:level="1">
<inist:fA14 i1="09">
<s1>Medical University of South Carolina</s1>
<s2>Charleston</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Medical University of South Carolina</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Fortes, Claudio Q" sort="Fortes, Claudio Q" uniqKey="Fortes C" first="Claudio Q." last="Fortes">Claudio Q. Fortes</name>
<affiliation wicri:level="3">
<inist:fA14 i1="10">
<s1>Hospital Universitario Clementino Fraga Filho</s1>
<s2>Rio de Janeiro</s2>
<s3>BRA</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Brésil</country>
<placeName>
<settlement type="city">Rio de Janeiro</settlement>
<region type="state">État de Rio de Janeiro</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Anguera, Ignasi" sort="Anguera, Ignasi" uniqKey="Anguera I" first="Ignasi" last="Anguera">Ignasi Anguera</name>
<affiliation wicri:level="1">
<inist:fA14 i1="11">
<s1>Hospital de Sabadell</s1>
<s2>Sabadell</s2>
<s3>ESP</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<wicri:noRegion>Hospital de Sabadell</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Athan, Eugene" sort="Athan, Eugene" uniqKey="Athan E" first="Eugene" last="Athan">Eugene Athan</name>
<affiliation wicri:level="1">
<inist:fA14 i1="12">
<s1>Geelong Hospital</s1>
<s2>Geelong</s2>
<s3>AUS</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Geelong Hospital</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Jones, Philip" sort="Jones, Philip" uniqKey="Jones P" first="Philip" last="Jones">Philip Jones</name>
<affiliation wicri:level="3">
<inist:fA14 i1="13">
<s1>Prince of Wales Hospital</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName>
<settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Van Der Meer, Jan T M" sort="Van Der Meer, Jan T M" uniqKey="Van Der Meer J" first="Jan T. M." last="Van Der Meer">Jan T. M. Van Der Meer</name>
<affiliation wicri:level="4">
<inist:fA14 i1="14">
<s1>Academic Medical Center, University of Amsterdam</s1>
<s3>NLD</s3>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region>Hollande-Septentrionale</region>
</placeName>
<orgName type="university">Université d'Amsterdam</orgName>
</affiliation>
</author>
<author>
<name sortKey="Elliott, Tom S J" sort="Elliott, Tom S J" uniqKey="Elliott T" first="Tom S. J." last="Elliott">Tom S. J. Elliott</name>
<affiliation wicri:level="1">
<inist:fA14 i1="15">
<s1>Queen Elizabeth Hospital</s1>
<s2>Birmingham, England</s2>
<s3>GBR</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>Queen Elizabeth Hospital</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Levine, Donald P" sort="Levine, Donald P" uniqKey="Levine D" first="Donald P." last="Levine">Donald P. Levine</name>
<affiliation wicri:level="1">
<inist:fA14 i1="16">
<s1>Wayne State University</s1>
<s2>Detroit, Mich</s2>
<s3>USA</s3>
<sZ>20 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Wayne State University</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Bayer, Arnold S" sort="Bayer, Arnold S" uniqKey="Bayer A" first="Arnold S." last="Bayer">Arnold S. Bayer</name>
<affiliation wicri:level="3">
<inist:fA14 i1="17">
<s1>Harbor-UCLA Medical Center and the LA Biomedical Research Institute</s1>
<s2>Los Angeles</s2>
<s3>USA</s3>
<sZ>21 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
</affiliation>
</author>
</analytic>
<series>
<title level="j" type="main">JAMA, the journal of the American Medical Association</title>
<title level="j" type="abbreviated">JAMA j. Am. Med. Assoc.</title>
<idno type="ISSN">0098-7484</idno>
<imprint>
<date when="2005">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt>
<title level="j" type="main">JAMA, the journal of the American Medical Association</title>
<title level="j" type="abbreviated">JAMA j. Am. Med. Assoc.</title>
<idno type="ISSN">0098-7484</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Endocarditis</term>
<term>Medicine</term>
<term>Staphylococcal infection</term>
<term>Staphylococcus aureus</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Endocardite</term>
<term>Staphylococcus aureus</term>
<term>Staphylococcie</term>
<term>Médecine</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Médecine</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Context The global significance of infective endocarditis (IE) caused by Staphylococcus aureus is unknown. Objectives To document the international emergence of health care-associated S aureus IE and methicillin-resistant S aureus (MRSA) IE and to evaluate regional variation in patients with S aureus IE. Design, Setting, and Participants Prospective observational cohort study set in 39 medical centers in 16 countries. Participants were a population of 1779 patients with definite IE as defined by Duke criteria who were enrolled in the International Collaboration on Endocarditis-Prospective Cohort Study from June 2000 to December 2003. Main Outcome Measure In-hospital mortality. Results S aureus was the most common pathogen among the 1779 cases of definite IE in the International Collaboration on Endocarditis Prospective-Cohort Study (558 patients, 31.4%). Health care-associated infection was the most common form of S aureus IE (218 patients, 39.1%), accounting for 25.9% (Australia/New Zealand) to 54.2% (Brazil) of cases. Most patients with health care-associated S aureus I E (131 patients, 60.1 %) acquired the infection outside of the hospital. MRSA IE was more common in the United States (37.2%) and Brazil (37.5%) than in Europe/Middle East (23.7%) and Australia/ New Zealand (15.5%, P<.001). Persistent bacteremia was independently associated with MRSA IE (odds ratio, 6.2; 95% confidence interval, 2.9-13.2). Patients in the United States were most likely to be hemodialysis dependent, to have diabetes, to have a presumed intravascular device source, to receive vancomycin, to be infected with MRSA, and to have persistent bacteremia (P<.001 for all comparisons). Conclusions S aureus is the leading cause of IE in many regions of the world. Characteristics of patients with S aureus IE vary significantly by region. Further studies are required to determine the causes of regional variation.</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>Australie</li>
<li>Brésil</li>
<li>Croatie</li>
<li>Espagne</li>
<li>France</li>
<li>Israël</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region>
<li>Bourgogne-Franche-Comté</li>
<li>Californie</li>
<li>Franche-Comté</li>
<li>Hollande-Septentrionale</li>
<li>Nouvelle-Galles du Sud</li>
<li>Victoria (État)</li>
<li>État de Rio de Janeiro</li>
</region>
<settlement>
<li>Amsterdam</li>
<li>Besançon</li>
<li>Los Angeles</li>
<li>Melbourne</li>
<li>Rio de Janeiro</li>
<li>Sydney</li>
</settlement>
<orgName>
<li>Université d'Amsterdam</li>
</orgName>
</list>
<tree>
<country name="États-Unis">
<noRegion>
<name sortKey="Fowler, Vance G Jr" sort="Fowler, Vance G Jr" uniqKey="Fowler V" first="Vance G. Jr" last="Fowler">Vance G. Jr Fowler</name>
</noRegion>
<name sortKey="Abrutyn, Elias" sort="Abrutyn, Elias" uniqKey="Abrutyn E" first="Elias" last="Abrutyn">Elias Abrutyn</name>
<name sortKey="Anstrom, Kevin J" sort="Anstrom, Kevin J" uniqKey="Anstrom K" first="Kevin J." last="Anstrom">Kevin J. Anstrom</name>
<name sortKey="Bayer, Arnold S" sort="Bayer, Arnold S" uniqKey="Bayer A" first="Arnold S." last="Bayer">Arnold S. Bayer</name>
<name sortKey="Bradley, Suzanne F" sort="Bradley, Suzanne F" uniqKey="Bradley S" first="Suzanne F." last="Bradley">Suzanne F. Bradley</name>
<name sortKey="Cabell, Christopher H" sort="Cabell, Christopher H" uniqKey="Cabell C" first="Christopher H." last="Cabell">Christopher H. Cabell</name>
<name sortKey="Levine, Donald P" sort="Levine, Donald P" uniqKey="Levine D" first="Donald P." last="Levine">Donald P. Levine</name>
<name sortKey="Pappas, Paul A" sort="Pappas, Paul A" uniqKey="Pappas P" first="Paul A." last="Pappas">Paul A. Pappas</name>
<name sortKey="Ralph Corey, Llb G" sort="Ralph Corey, Llb G" uniqKey="Ralph Corey L" first="Llb G." last="Ralph Corey">Llb G. Ralph Corey</name>
<name sortKey="Wray, Dannah" sort="Wray, Dannah" uniqKey="Wray D" first="Dannah" last="Wray">Dannah Wray</name>
</country>
<country name="Espagne">
<noRegion>
<name sortKey="Miro, Jose M" sort="Miro, Jose M" uniqKey="Miro J" first="Jose M." last="Miro">Jose M. Miro</name>
</noRegion>
<name sortKey="Anguera, Ignasi" sort="Anguera, Ignasi" uniqKey="Anguera I" first="Ignasi" last="Anguera">Ignasi Anguera</name>
</country>
<country name="France">
<region name="Bourgogne-Franche-Comté">
<name sortKey="Hoen, Bruno" sort="Hoen, Bruno" uniqKey="Hoen B" first="Bruno" last="Hoen">Bruno Hoen</name>
</region>
</country>
<country name="Israël">
<noRegion>
<name sortKey="Rubinstein, Ethan" sort="Rubinstein, Ethan" uniqKey="Rubinstein E" first="Ethan" last="Rubinstein">Ethan Rubinstein</name>
</noRegion>
</country>
<country name="Australie">
<region name="Victoria (État)">
<name sortKey="Spelman, Denis" sort="Spelman, Denis" uniqKey="Spelman D" first="Denis" last="Spelman">Denis Spelman</name>
</region>
<name sortKey="Athan, Eugene" sort="Athan, Eugene" uniqKey="Athan E" first="Eugene" last="Athan">Eugene Athan</name>
<name sortKey="Jones, Philip" sort="Jones, Philip" uniqKey="Jones P" first="Philip" last="Jones">Philip Jones</name>
</country>
<country name="Croatie">
<noRegion>
<name sortKey="Barsic, Bruno" sort="Barsic, Bruno" uniqKey="Barsic B" first="Bruno" last="Barsic">Bruno Barsic</name>
</noRegion>
</country>
<country name="Brésil">
<region name="État de Rio de Janeiro">
<name sortKey="Fortes, Claudio Q" sort="Fortes, Claudio Q" uniqKey="Fortes C" first="Claudio Q." last="Fortes">Claudio Q. Fortes</name>
</region>
</country>
<country name="Pays-Bas">
<region name="Hollande-Septentrionale">
<name sortKey="Van Der Meer, Jan T M" sort="Van Der Meer, Jan T M" uniqKey="Van Der Meer J" first="Jan T. M." last="Van Der Meer">Jan T. M. Van Der Meer</name>
</region>
</country>
<country name="Royaume-Uni">
<noRegion>
<name sortKey="Elliott, Tom S J" sort="Elliott, Tom S J" uniqKey="Elliott T" first="Tom S. J." last="Elliott">Tom S. J. Elliott</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

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