Staphylococcus aureus endocarditis : A consequence of medical progress
Identifieur interne : 004909 ( PascalFrancis/Corpus ); précédent : 004908; suivant : 004910Staphylococcus aureus endocarditis : A consequence of medical progress
Auteurs : Vance G. Jr Fowler ; Jose M. Miro ; Bruno Hoen ; Christopher H. Cabell ; Elias Abrutyn ; Ethan Rubinstein ; Llb G. Ralph Corey ; Denis Spelman ; Suzanne F. Bradley ; Bruno Barsic ; Paul A. Pappas ; Kevin J. Anstrom ; Dannah Wray ; Claudio Q. Fortes ; Ignasi Anguera ; Eugene Athan ; Philip Jones ; Jan T. M. Van Der Meer ; Tom S. J. Elliott ; Donald P. Levine ; Arnold S. BayerSource :
- JAMA, the journal of the American Medical Association [ 0098-7484 ] ; 2005.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
Context The global significance of infective endocarditis (IE) caused by Staphylococcus aureus is unknown. Objectives To document the international emergence of health care-associated S aureus IE and methicillin-resistant S aureus (MRSA) IE and to evaluate regional variation in patients with S aureus IE. Design, Setting, and Participants Prospective observational cohort study set in 39 medical centers in 16 countries. Participants were a population of 1779 patients with definite IE as defined by Duke criteria who were enrolled in the International Collaboration on Endocarditis-Prospective Cohort Study from June 2000 to December 2003. Main Outcome Measure In-hospital mortality. Results S aureus was the most common pathogen among the 1779 cases of definite IE in the International Collaboration on Endocarditis Prospective-Cohort Study (558 patients, 31.4%). Health care-associated infection was the most common form of S aureus IE (218 patients, 39.1%), accounting for 25.9% (Australia/New Zealand) to 54.2% (Brazil) of cases. Most patients with health care-associated S aureus I E (131 patients, 60.1 %) acquired the infection outside of the hospital. MRSA IE was more common in the United States (37.2%) and Brazil (37.5%) than in Europe/Middle East (23.7%) and Australia/ New Zealand (15.5%, P<.001). Persistent bacteremia was independently associated with MRSA IE (odds ratio, 6.2; 95% confidence interval, 2.9-13.2). Patients in the United States were most likely to be hemodialysis dependent, to have diabetes, to have a presumed intravascular device source, to receive vancomycin, to be infected with MRSA, and to have persistent bacteremia (P<.001 for all comparisons). Conclusions S aureus is the leading cause of IE in many regions of the world. Characteristics of patients with S aureus IE vary significantly by region. Further studies are required to determine the causes of regional variation.
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Format Inist (serveur)
NO : | PASCAL 05-0289831 INIST |
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ET : | Staphylococcus aureus endocarditis : A consequence of medical progress |
AU : | FOWLER (Vance G. JR); MIRO (Jose M.); HOEN (Bruno); CABELL (Christopher H.); ABRUTYN (Elias); RUBINSTEIN (Ethan); RALPH COREY (Llb G.); SPELMAN (Denis); BRADLEY (Suzanne F.); BARSIC (Bruno); PAPPAS (Paul A.); ANSTROM (Kevin J.); WRAY (Dannah); FORTES (Claudio Q.); ANGUERA (Ignasi); ATHAN (Eugene); JONES (Philip); VAN DER MEER (Jan T. M.); ELLIOTT (Tom S. J.); LEVINE (Donald P.); BAYER (Arnold S.) |
AF : | Duke University Medical Center/Durham, NC/Etats-Unis (1 aut., 4 aut., 7 aut., 11 aut., 12 aut.); Hospital Clinic-IDIBAPS, University of Barcelona/Espagne (2 aut.); Hôpital Saint-Jacques/Besançon/France (3 aut.); Drexel University College of Medicine/Philadelphia, Pa/Etats-Unis (5 aut.); Tel Aviv University, School of Medicine/Tel Aviv/Israël (6 aut.); Alfred Hospital/Melbourne/Australie (8 aut.); University of Michigan/Ann Arbor/Etats-Unis (9 aut.); University Hospital for Infectious Diseases/Zagreb/Croatie (10 aut.); Medical University of South Carolina/Charleston/Etats-Unis (13 aut.); Hospital Universitario Clementino Fraga Filho/Rio de Janeiro/Brésil (14 aut.); Hospital de Sabadell/Sabadell/Espagne (15 aut.); Geelong Hospital/Geelong/Australie (16 aut.); Prince of Wales Hospital/Sydney/Australie (17 aut.); Academic Medical Center, University of Amsterdam/Pays-Bas (18 aut.); Queen Elizabeth Hospital/Birmingham, England/Royaume-Uni (19 aut.); Wayne State University/Detroit, Mich/Etats-Unis (20 aut.); Harbor-UCLA Medical Center and the LA Biomedical Research Institute/Los Angeles/Etats-Unis (21 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | JAMA, the journal of the American Medical Association; ISSN 0098-7484; Etats-Unis; Da. 2005; Vol. 293; No. 24; Pp. 3012-3021; Bibl. 37 ref. |
LA : | Anglais |
EA : | Context The global significance of infective endocarditis (IE) caused by Staphylococcus aureus is unknown. Objectives To document the international emergence of health care-associated S aureus IE and methicillin-resistant S aureus (MRSA) IE and to evaluate regional variation in patients with S aureus IE. Design, Setting, and Participants Prospective observational cohort study set in 39 medical centers in 16 countries. Participants were a population of 1779 patients with definite IE as defined by Duke criteria who were enrolled in the International Collaboration on Endocarditis-Prospective Cohort Study from June 2000 to December 2003. Main Outcome Measure In-hospital mortality. Results S aureus was the most common pathogen among the 1779 cases of definite IE in the International Collaboration on Endocarditis Prospective-Cohort Study (558 patients, 31.4%). Health care-associated infection was the most common form of S aureus IE (218 patients, 39.1%), accounting for 25.9% (Australia/New Zealand) to 54.2% (Brazil) of cases. Most patients with health care-associated S aureus I E (131 patients, 60.1 %) acquired the infection outside of the hospital. MRSA IE was more common in the United States (37.2%) and Brazil (37.5%) than in Europe/Middle East (23.7%) and Australia/ New Zealand (15.5%, P<.001). Persistent bacteremia was independently associated with MRSA IE (odds ratio, 6.2; 95% confidence interval, 2.9-13.2). Patients in the United States were most likely to be hemodialysis dependent, to have diabetes, to have a presumed intravascular device source, to receive vancomycin, to be infected with MRSA, and to have persistent bacteremia (P<.001 for all comparisons). Conclusions S aureus is the leading cause of IE in many regions of the world. Characteristics of patients with S aureus IE vary significantly by region. Further studies are required to determine the causes of regional variation. |
CC : | 002B01; 002B12A04 |
FD : | Endocardite; Staphylococcus aureus; Staphylococcie; Médecine |
FG : | Micrococcaceae; Micrococcales; Bactérie; Bactériose; Infection; Appareil circulatoire pathologie; Cardiopathie; Endocarde pathologie |
ED : | Endocarditis; Staphylococcus aureus; Staphylococcal infection; Medicine |
EG : | Micrococcaceae; Micrococcales; Bacteria; Bacteriosis; Infection; Cardiovascular disease; Heart disease; Endocardial disease |
SD : | Endocarditis; Staphylococcus aureus; Estafilococia; Medicina |
LO : | INIST-5051.354000138115190020 |
ID : | 05-0289831 |
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Pascal:05-0289831Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Staphylococcus aureus endocarditis : A consequence of medical progress</title>
<author><name sortKey="Fowler, Vance G Jr" sort="Fowler, Vance G Jr" uniqKey="Fowler V" first="Vance G. Jr" last="Fowler">Vance G. Jr Fowler</name>
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<author><name sortKey="Hoen, Bruno" sort="Hoen, Bruno" uniqKey="Hoen B" first="Bruno" last="Hoen">Bruno Hoen</name>
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<author><name sortKey="Rubinstein, Ethan" sort="Rubinstein, Ethan" uniqKey="Rubinstein E" first="Ethan" last="Rubinstein">Ethan Rubinstein</name>
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<author><name sortKey="Spelman, Denis" sort="Spelman, Denis" uniqKey="Spelman D" first="Denis" last="Spelman">Denis Spelman</name>
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<author><name sortKey="Bradley, Suzanne F" sort="Bradley, Suzanne F" uniqKey="Bradley S" first="Suzanne F." last="Bradley">Suzanne F. Bradley</name>
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<author><name sortKey="Barsic, Bruno" sort="Barsic, Bruno" uniqKey="Barsic B" first="Bruno" last="Barsic">Bruno Barsic</name>
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<author><name sortKey="Anstrom, Kevin J" sort="Anstrom, Kevin J" uniqKey="Anstrom K" first="Kevin J." last="Anstrom">Kevin J. Anstrom</name>
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<author><name sortKey="Fortes, Claudio Q" sort="Fortes, Claudio Q" uniqKey="Fortes C" first="Claudio Q." last="Fortes">Claudio Q. Fortes</name>
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<author><name sortKey="Anguera, Ignasi" sort="Anguera, Ignasi" uniqKey="Anguera I" first="Ignasi" last="Anguera">Ignasi Anguera</name>
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<author><name sortKey="Elliott, Tom S J" sort="Elliott, Tom S J" uniqKey="Elliott T" first="Tom S. J." last="Elliott">Tom S. J. Elliott</name>
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<s3>GBR</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Levine, Donald P" sort="Levine, Donald P" uniqKey="Levine D" first="Donald P." last="Levine">Donald P. Levine</name>
<affiliation><inist:fA14 i1="16"><s1>Wayne State University</s1>
<s2>Detroit, Mich</s2>
<s3>USA</s3>
<sZ>20 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Bayer, Arnold S" sort="Bayer, Arnold S" uniqKey="Bayer A" first="Arnold S." last="Bayer">Arnold S. Bayer</name>
<affiliation><inist:fA14 i1="17"><s1>Harbor-UCLA Medical Center and the LA Biomedical Research Institute</s1>
<s2>Los Angeles</s2>
<s3>USA</s3>
<sZ>21 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">JAMA, the journal of the American Medical Association</title>
<title level="j" type="abbreviated">JAMA j. Am. Med. Assoc.</title>
<idno type="ISSN">0098-7484</idno>
<imprint><date when="2005">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">JAMA, the journal of the American Medical Association</title>
<title level="j" type="abbreviated">JAMA j. Am. Med. Assoc.</title>
<idno type="ISSN">0098-7484</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Endocarditis</term>
<term>Medicine</term>
<term>Staphylococcal infection</term>
<term>Staphylococcus aureus</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Endocardite</term>
<term>Staphylococcus aureus</term>
<term>Staphylococcie</term>
<term>Médecine</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Context The global significance of infective endocarditis (IE) caused by Staphylococcus aureus is unknown. Objectives To document the international emergence of health care-associated S aureus IE and methicillin-resistant S aureus (MRSA) IE and to evaluate regional variation in patients with S aureus IE. Design, Setting, and Participants Prospective observational cohort study set in 39 medical centers in 16 countries. Participants were a population of 1779 patients with definite IE as defined by Duke criteria who were enrolled in the International Collaboration on Endocarditis-Prospective Cohort Study from June 2000 to December 2003. Main Outcome Measure In-hospital mortality. Results S aureus was the most common pathogen among the 1779 cases of definite IE in the International Collaboration on Endocarditis Prospective-Cohort Study (558 patients, 31.4%). Health care-associated infection was the most common form of S aureus IE (218 patients, 39.1%), accounting for 25.9% (Australia/New Zealand) to 54.2% (Brazil) of cases. Most patients with health care-associated S aureus I E (131 patients, 60.1 %) acquired the infection outside of the hospital. MRSA IE was more common in the United States (37.2%) and Brazil (37.5%) than in Europe/Middle East (23.7%) and Australia/ New Zealand (15.5%, P<.001). Persistent bacteremia was independently associated with MRSA IE (odds ratio, 6.2; 95% confidence interval, 2.9-13.2). Patients in the United States were most likely to be hemodialysis dependent, to have diabetes, to have a presumed intravascular device source, to receive vancomycin, to be infected with MRSA, and to have persistent bacteremia (P<.001 for all comparisons). Conclusions S aureus is the leading cause of IE in many regions of the world. Characteristics of patients with S aureus IE vary significantly by region. Further studies are required to determine the causes of regional variation.</div>
</front>
</TEI>
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<fA08 i1="01" i2="1" l="ENG"><s1>Staphylococcus aureus endocarditis : A consequence of medical progress</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>FOWLER (Vance G. JR)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>MIRO (Jose M.)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>HOEN (Bruno)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>CABELL (Christopher H.)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>ABRUTYN (Elias)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>RUBINSTEIN (Ethan)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>RALPH COREY (Llb G.)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>SPELMAN (Denis)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>BRADLEY (Suzanne F.)</s1>
</fA11>
<fA11 i1="10" i2="1"><s1>BARSIC (Bruno)</s1>
</fA11>
<fA11 i1="11" i2="1"><s1>PAPPAS (Paul A.)</s1>
</fA11>
<fA11 i1="12" i2="1"><s1>ANSTROM (Kevin J.)</s1>
</fA11>
<fA11 i1="13" i2="1"><s1>WRAY (Dannah)</s1>
</fA11>
<fA11 i1="14" i2="1"><s1>FORTES (Claudio Q.)</s1>
</fA11>
<fA11 i1="15" i2="1"><s1>ANGUERA (Ignasi)</s1>
</fA11>
<fA11 i1="16" i2="1"><s1>ATHAN (Eugene)</s1>
</fA11>
<fA11 i1="17" i2="1"><s1>JONES (Philip)</s1>
</fA11>
<fA11 i1="18" i2="1"><s1>VAN DER MEER (Jan T. M.)</s1>
</fA11>
<fA11 i1="19" i2="1"><s1>ELLIOTT (Tom S. J.)</s1>
</fA11>
<fA11 i1="20" i2="1"><s1>LEVINE (Donald P.)</s1>
</fA11>
<fA11 i1="21" i2="1"><s1>BAYER (Arnold S.)</s1>
</fA11>
<fA14 i1="01"><s1>Duke University Medical Center</s1>
<s2>Durham, NC</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>12 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Hospital Clinic-IDIBAPS, University of Barcelona</s1>
<s3>ESP</s3>
<sZ>2 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Hôpital Saint-Jacques</s1>
<s2>Besançon</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Drexel University College of Medicine</s1>
<s2>Philadelphia, Pa</s2>
<s3>USA</s3>
<sZ>5 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>Tel Aviv University, School of Medicine</s1>
<s2>Tel Aviv</s2>
<s3>ISR</s3>
<sZ>6 aut.</sZ>
</fA14>
<fA14 i1="06"><s1>Alfred Hospital</s1>
<s2>Melbourne</s2>
<s3>AUS</s3>
<sZ>8 aut.</sZ>
</fA14>
<fA14 i1="07"><s1>University of Michigan</s1>
<s2>Ann Arbor</s2>
<s3>USA</s3>
<sZ>9 aut.</sZ>
</fA14>
<fA14 i1="08"><s1>University Hospital for Infectious Diseases</s1>
<s2>Zagreb</s2>
<s3>HRV</s3>
<sZ>10 aut.</sZ>
</fA14>
<fA14 i1="09"><s1>Medical University of South Carolina</s1>
<s2>Charleston</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
</fA14>
<fA14 i1="10"><s1>Hospital Universitario Clementino Fraga Filho</s1>
<s2>Rio de Janeiro</s2>
<s3>BRA</s3>
<sZ>14 aut.</sZ>
</fA14>
<fA14 i1="11"><s1>Hospital de Sabadell</s1>
<s2>Sabadell</s2>
<s3>ESP</s3>
<sZ>15 aut.</sZ>
</fA14>
<fA14 i1="12"><s1>Geelong Hospital</s1>
<s2>Geelong</s2>
<s3>AUS</s3>
<sZ>16 aut.</sZ>
</fA14>
<fA14 i1="13"><s1>Prince of Wales Hospital</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>17 aut.</sZ>
</fA14>
<fA14 i1="14"><s1>Academic Medical Center, University of Amsterdam</s1>
<s3>NLD</s3>
<sZ>18 aut.</sZ>
</fA14>
<fA14 i1="15"><s1>Queen Elizabeth Hospital</s1>
<s2>Birmingham, England</s2>
<s3>GBR</s3>
<sZ>19 aut.</sZ>
</fA14>
<fA14 i1="16"><s1>Wayne State University</s1>
<s2>Detroit, Mich</s2>
<s3>USA</s3>
<sZ>20 aut.</sZ>
</fA14>
<fA14 i1="17"><s1>Harbor-UCLA Medical Center and the LA Biomedical Research Institute</s1>
<s2>Los Angeles</s2>
<s3>USA</s3>
<sZ>21 aut.</sZ>
</fA14>
<fA17 i1="01" i2="1"><s1>ICE Investigators</s1>
<s3>INC</s3>
</fA17>
<fA20><s1>3012-3021</s1>
</fA20>
<fA21><s1>2005</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
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<s2>5051</s2>
<s5>354000138115190020</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2005 INIST-CNRS. All rights reserved.</s1>
</fA44>
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</fA45>
<fA47 i1="01" i2="1"><s0>05-0289831</s0>
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<fA60><s1>P</s1>
</fA60>
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<fA64 i1="01" i2="1"><s0>JAMA, the journal of the American Medical Association</s0>
</fA64>
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</fA66>
<fC01 i1="01" l="ENG"><s0>Context The global significance of infective endocarditis (IE) caused by Staphylococcus aureus is unknown. Objectives To document the international emergence of health care-associated S aureus IE and methicillin-resistant S aureus (MRSA) IE and to evaluate regional variation in patients with S aureus IE. Design, Setting, and Participants Prospective observational cohort study set in 39 medical centers in 16 countries. Participants were a population of 1779 patients with definite IE as defined by Duke criteria who were enrolled in the International Collaboration on Endocarditis-Prospective Cohort Study from June 2000 to December 2003. Main Outcome Measure In-hospital mortality. Results S aureus was the most common pathogen among the 1779 cases of definite IE in the International Collaboration on Endocarditis Prospective-Cohort Study (558 patients, 31.4%). Health care-associated infection was the most common form of S aureus IE (218 patients, 39.1%), accounting for 25.9% (Australia/New Zealand) to 54.2% (Brazil) of cases. Most patients with health care-associated S aureus I E (131 patients, 60.1 %) acquired the infection outside of the hospital. MRSA IE was more common in the United States (37.2%) and Brazil (37.5%) than in Europe/Middle East (23.7%) and Australia/ New Zealand (15.5%, P<.001). Persistent bacteremia was independently associated with MRSA IE (odds ratio, 6.2; 95% confidence interval, 2.9-13.2). Patients in the United States were most likely to be hemodialysis dependent, to have diabetes, to have a presumed intravascular device source, to receive vancomycin, to be infected with MRSA, and to have persistent bacteremia (P<.001 for all comparisons). Conclusions S aureus is the leading cause of IE in many regions of the world. Characteristics of patients with S aureus IE vary significantly by region. Further studies are required to determine the causes of regional variation.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B01</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B12A04</s0>
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<fC03 i1="01" i2="X" l="FRE"><s0>Endocardite</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Endocarditis</s0>
<s5>01</s5>
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<fC03 i1="01" i2="X" l="SPA"><s0>Endocarditis</s0>
<s5>01</s5>
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<fC03 i1="02" i2="X" l="FRE"><s0>Staphylococcus aureus</s0>
<s2>NS</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Staphylococcus aureus</s0>
<s2>NS</s2>
<s5>02</s5>
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<fC03 i1="02" i2="X" l="SPA"><s0>Staphylococcus aureus</s0>
<s2>NS</s2>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Staphylococcie</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Staphylococcal infection</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Estafilococia</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Médecine</s0>
<s5>05</s5>
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<fC03 i1="04" i2="X" l="ENG"><s0>Medicine</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Medicina</s0>
<s5>05</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Micrococcaceae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Micrococcaceae</s0>
<s2>NS</s2>
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<fC07 i1="01" i2="X" l="SPA"><s0>Micrococcaceae</s0>
<s2>NS</s2>
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<s2>NS</s2>
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<fC07 i1="02" i2="X" l="ENG"><s0>Micrococcales</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Micrococcales</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Bactérie</s0>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Bacteria</s0>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Bacteria</s0>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Bactériose</s0>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Bacteriosis</s0>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Bacteriosis</s0>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Infection</s0>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Infection</s0>
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<fC07 i1="05" i2="X" l="SPA"><s0>Infección</s0>
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<fC07 i1="06" i2="X" l="FRE"><s0>Appareil circulatoire pathologie</s0>
<s5>37</s5>
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<s5>37</s5>
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<s5>38</s5>
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<fC07 i1="07" i2="X" l="ENG"><s0>Heart disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Cardiopatía</s0>
<s5>38</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Endocarde pathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Endocardial disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Endocardio patología</s0>
<s5>39</s5>
</fC07>
<fN21><s1>199</s1>
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<server><NO>PASCAL 05-0289831 INIST</NO>
<ET>Staphylococcus aureus endocarditis : A consequence of medical progress</ET>
<AU>FOWLER (Vance G. JR); MIRO (Jose M.); HOEN (Bruno); CABELL (Christopher H.); ABRUTYN (Elias); RUBINSTEIN (Ethan); RALPH COREY (Llb G.); SPELMAN (Denis); BRADLEY (Suzanne F.); BARSIC (Bruno); PAPPAS (Paul A.); ANSTROM (Kevin J.); WRAY (Dannah); FORTES (Claudio Q.); ANGUERA (Ignasi); ATHAN (Eugene); JONES (Philip); VAN DER MEER (Jan T. M.); ELLIOTT (Tom S. J.); LEVINE (Donald P.); BAYER (Arnold S.)</AU>
<AF>Duke University Medical Center/Durham, NC/Etats-Unis (1 aut., 4 aut., 7 aut., 11 aut., 12 aut.); Hospital Clinic-IDIBAPS, University of Barcelona/Espagne (2 aut.); Hôpital Saint-Jacques/Besançon/France (3 aut.); Drexel University College of Medicine/Philadelphia, Pa/Etats-Unis (5 aut.); Tel Aviv University, School of Medicine/Tel Aviv/Israël (6 aut.); Alfred Hospital/Melbourne/Australie (8 aut.); University of Michigan/Ann Arbor/Etats-Unis (9 aut.); University Hospital for Infectious Diseases/Zagreb/Croatie (10 aut.); Medical University of South Carolina/Charleston/Etats-Unis (13 aut.); Hospital Universitario Clementino Fraga Filho/Rio de Janeiro/Brésil (14 aut.); Hospital de Sabadell/Sabadell/Espagne (15 aut.); Geelong Hospital/Geelong/Australie (16 aut.); Prince of Wales Hospital/Sydney/Australie (17 aut.); Academic Medical Center, University of Amsterdam/Pays-Bas (18 aut.); Queen Elizabeth Hospital/Birmingham, England/Royaume-Uni (19 aut.); Wayne State University/Detroit, Mich/Etats-Unis (20 aut.); Harbor-UCLA Medical Center and the LA Biomedical Research Institute/Los Angeles/Etats-Unis (21 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>JAMA, the journal of the American Medical Association; ISSN 0098-7484; Etats-Unis; Da. 2005; Vol. 293; No. 24; Pp. 3012-3021; Bibl. 37 ref.</SO>
<LA>Anglais</LA>
<EA>Context The global significance of infective endocarditis (IE) caused by Staphylococcus aureus is unknown. Objectives To document the international emergence of health care-associated S aureus IE and methicillin-resistant S aureus (MRSA) IE and to evaluate regional variation in patients with S aureus IE. Design, Setting, and Participants Prospective observational cohort study set in 39 medical centers in 16 countries. Participants were a population of 1779 patients with definite IE as defined by Duke criteria who were enrolled in the International Collaboration on Endocarditis-Prospective Cohort Study from June 2000 to December 2003. Main Outcome Measure In-hospital mortality. Results S aureus was the most common pathogen among the 1779 cases of definite IE in the International Collaboration on Endocarditis Prospective-Cohort Study (558 patients, 31.4%). Health care-associated infection was the most common form of S aureus IE (218 patients, 39.1%), accounting for 25.9% (Australia/New Zealand) to 54.2% (Brazil) of cases. Most patients with health care-associated S aureus I E (131 patients, 60.1 %) acquired the infection outside of the hospital. MRSA IE was more common in the United States (37.2%) and Brazil (37.5%) than in Europe/Middle East (23.7%) and Australia/ New Zealand (15.5%, P<.001). Persistent bacteremia was independently associated with MRSA IE (odds ratio, 6.2; 95% confidence interval, 2.9-13.2). Patients in the United States were most likely to be hemodialysis dependent, to have diabetes, to have a presumed intravascular device source, to receive vancomycin, to be infected with MRSA, and to have persistent bacteremia (P<.001 for all comparisons). Conclusions S aureus is the leading cause of IE in many regions of the world. Characteristics of patients with S aureus IE vary significantly by region. Further studies are required to determine the causes of regional variation.</EA>
<CC>002B01; 002B12A04</CC>
<FD>Endocardite; Staphylococcus aureus; Staphylococcie; Médecine</FD>
<FG>Micrococcaceae; Micrococcales; Bactérie; Bactériose; Infection; Appareil circulatoire pathologie; Cardiopathie; Endocarde pathologie</FG>
<ED>Endocarditis; Staphylococcus aureus; Staphylococcal infection; Medicine</ED>
<EG>Micrococcaceae; Micrococcales; Bacteria; Bacteriosis; Infection; Cardiovascular disease; Heart disease; Endocardial disease</EG>
<SD>Endocarditis; Staphylococcus aureus; Estafilococia; Medicina</SD>
<LO>INIST-5051.354000138115190020</LO>
<ID>05-0289831</ID>
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