Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes
Identifieur interne : 002D52 ( Main/Exploration ); précédent : 002D51; suivant : 002D53Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes
Auteurs : Alexander Teumer [Allemagne] ; Adrienne Tin [États-Unis] ; Rossella Sorice [Italie] ; Mathias Gorski [Allemagne] ; Nan Cher Yeo [États-Unis] ; Audrey Y. Chu [États-Unis] ; Man Li [États-Unis] ; Yong Li [Allemagne] ; Vladan Mijatovic [Italie] ; Yi-An Ko [États-Unis] ; Daniel Taliun [Italie] ; Alessandro Luciani [Suisse] ; Ming-Huei Chen [États-Unis] ; Qiong Yang [États-Unis] ; Meredith C. Foster [États-Unis] ; Matthias Olden [Allemagne] ; Linda T. Hiraki [Canada] ; Bamidele O. Tayo [États-Unis] ; Christian Fuchsberger [Italie] ; Aida Karina Dieffenbach [Allemagne] ; Alan R. Shuldiner [États-Unis] ; Albert V. Smith [Islande] ; Allison M. Zappa [États-Unis] ; Antonio Lupo [Italie] ; Barbara Kollerits [Autriche] ; Belen Ponte [Suisse] ; Bénédicte Stengel [France] ; Bernhard K. Kr Mer [Allemagne] ; Bernhard Paulweber [Autriche] ; Braxton D. Mitchell [États-Unis] ; Caroline Hayward [Royaume-Uni] ; Catherine Helmer [France] ; Christa Meisinger [Allemagne] ; Christian Gieger [Allemagne] ; Christian M. Shaffer [États-Unis] ; Christian Müller [Allemagne] ; Claudia Langenberg [Royaume-Uni] ; Daniel Ackermann [Suisse] ; David Siscovick [États-Unis] ; Eric Boerwinkle [États-Unis] ; Florian Kronenberg [Autriche] ; Georg B. Ehret [Suisse] ; Georg Homuth [Allemagne] ; Gerard Waeber [Suisse] ; Gerjan Navis [Pays-Bas] ; Giovanni Gambaro [Italie] ; Giovanni Malerba [Italie] ; Gudny Eiriksdottir [Islande] ; Guo Li [États-Unis] ; H. Erich Wichmann [Allemagne] ; Harald Grallert [Allemagne] ; Henri Wallaschofski [Allemagne] ; Henry Völzke [Allemagne] ; Herrmann Brenner [Allemagne] ; Holly Kramer [États-Unis] ; I. Mateo Leach [Pays-Bas] ; Igor Rudan [Royaume-Uni] ; Hans L. Hillege [Pays-Bas] ; Jacques S. Beckmann [Suisse] ; Jean Charles Lambert [France] ; Jian'An Luan [Royaume-Uni] ; Jing Hua Zhao [Royaume-Uni] ; John Chalmers [Australie] ; Josef Coresh [États-Unis] ; Joshua C. Denny [États-Unis] ; Katja Butterbach [Allemagne] ; Lenore J. Launer [États-Unis] ; Luigi Ferrucci [États-Unis] ; Lyudmyla Kedenko [Autriche] ; Margot Haun [Autriche] ; Marie Metzger [France] ; Mark Woodward [États-Unis, Australie, Royaume-Uni] ; Matthew J. Hoffman [États-Unis] ; Matthias Nauck [Allemagne] ; Melanie Waldenberger [Allemagne] ; Menno Pruijm [Suisse] ; Murielle Bochud [Suisse] ; Myriam Rheinberger [Allemagne] ; Niek Verweij [Pays-Bas] ; Nicholas J. Wareham [Royaume-Uni] ; Nicole Endlich [Allemagne] ; Nicole Soranzo [Royaume-Uni] ; Ozren Polasek [Croatie] ; Pim Van Der Harst [Pays-Bas] ; Peter Paul Pramstaller [Italie] ; Peter Vollenweider [Suisse] ; Philipp S. Wild [Allemagne] ; Ron T. Gansevoort [Pays-Bas] ; Rainer Rettig [Allemagne] ; Reiner Biffar [Allemagne] ; Robert J. Carroll [États-Unis] ; Ronit Katz [États-Unis] ; Ruth J. F. Loos [Royaume-Uni, États-Unis] ; Shih-Jen Hwang [États-Unis] ; Stefan Coassin [Autriche] ; Sven Bergmann [Suisse] ; Sylvia E. Rosas [États-Unis] ; Sylvia Stracke [Allemagne] ; Tamara B. Harris [États-Unis] ; Tanguy Corre [Suisse] ; Tanja Zeller [Allemagne] ; Thomas Illig [Allemagne] ; Thor Aspelund [Islande] ; Toshiko Tanaka [États-Unis] ; Uwe Lendeckel [Allemagne] ; Uwe Völker [Allemagne] ; Vilmundur Gudnason [Islande] ; Vincent Chouraki [France] ; Wolfgang Koenig [Allemagne] ; Zoltan Kutalik [Suisse] ; Jeffrey R. O'Connell [États-Unis] ; Afshin Parsa [États-Unis] ; Iris M. Heid [Allemagne] ; Andrew D. Paterson [Canada] ; Ian H. De Boer [États-Unis] ; Olivier Devuyst [Suisse] ; Jozef Lazar [États-Unis] ; Karlhans Endlich [Allemagne] ; Katalin Susztak [États-Unis] ; Johanne Tremblay [Canada] ; Pavel Hamet [Canada] ; Howard J. Jacob [États-Unis] ; Carsten A. Böger [Allemagne] ; Caroline S. Fox [États-Unis] ; Cristian Pattaro [Italie] ; Anna Köttgen [États-Unis, Allemagne]Source :
- Diabetes [ 0012-1797 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Albuminurie (génétique), Albuminurie (étiologie), Animaux, Cathepsine C (génétique), Diabète de type 2 (), Diabète de type 2 (génétique), Diabète expérimental, Femelle, Humains, Mâle, Néphropathies diabétiques (génétique), Néphropathies diabétiques (étiologie), Polymorphisme de nucléotide simple, Protéines G rab (génétique), Protéines G rab (métabolisme), Prédisposition génétique à une maladie, Rats, Rein (métabolisme), Récepteurs de surface cellulaire (génétique), Sujet âgé, Sulfotransferases (génétique), Techniques de knock-out de gènes, Tubules rénaux (métabolisme), Étude d'association pangénomique.
- MESH :
- génétique : Albuminurie, Cathepsine C, Diabète de type 2, Néphropathies diabétiques, Protéines G rab, Récepteurs de surface cellulaire, Sulfotransferases.
- métabolisme : Protéines G rab, Rein, Tubules rénaux.
- étiologie : Albuminurie, Néphropathies diabétiques.
- Adulte, Adulte d'âge moyen, Animaux, Diabète de type 2, Diabète expérimental, Femelle, Humains, Mâle, Polymorphisme de nucléotide simple, Prédisposition génétique à une maladie, Rats, Sujet âgé, Techniques de knock-out de gènes, Étude d'association pangénomique.
English descriptors
- KwdEn :
- Adult, Aged, Albuminuria (etiology), Albuminuria (genetics), Animals, Cathepsin C (genetics), Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 2 (complications), Diabetes Mellitus, Type 2 (genetics), Diabetic Nephropathies (etiology), Diabetic Nephropathies (genetics), Female, Gene Knockout Techniques, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Kidney (metabolism), Kidney Tubules (metabolism), Male, Middle Aged, Polymorphism, Single Nucleotide, Rats, Receptors, Cell Surface (genetics), Sulfotransferases (genetics), rab GTP-Binding Proteins (genetics), rab GTP-Binding Proteins (metabolism).
- MESH :
- chemical , genetics : Cathepsin C, Receptors, Cell Surface, Sulfotransferases, rab GTP-Binding Proteins.
- complications : Diabetes Mellitus, Type 2.
- etiology : Albuminuria, Diabetic Nephropathies.
- genetics : Albuminuria, Diabetes Mellitus, Type 2, Diabetic Nephropathies.
- metabolism : Kidney, Kidney Tubules, rab GTP-Binding Proteins.
- Adult, Aged, Animals, Diabetes Mellitus, Experimental, Female, Gene Knockout Techniques, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Male, Middle Aged, Polymorphism, Single Nucleotide, Rats.
Abstract
Elevated concentrations of albumin in the urine, albuminuria, are a hallmark of diabetic kidney disease and are associated with an increased risk for end-stage renal disease and cardiovascular events. To gain insight into the pathophysiological mechanisms underlying albuminuria, we conducted meta-analyses of genome-wide association studies and independent replication in up to 5,825 individuals of European ancestry with diabetes and up to 46,061 without diabetes, followed by functional studies. Known associations of variants in
Url:
DOI: 10.2337/db15-1313
PubMed: 26631737
PubMed Central: 4764151
Affiliations:
- Allemagne, Australie, Autriche, Canada, Croatie, France, Islande, Italie, Pays-Bas, Royaume-Uni, Suisse, États-Unis
- Angleterre, Angleterre de l'Est, Aquitaine, Bade-Wurtemberg, Basse-Saxe, Bavière, Canton de Berne, Canton de Vaud, Canton de Zurich, District de Fribourg-en-Brisgau, District de Haute-Bavière, District de Karlsruhe, District de Tübingen, Groningue (province), Hambourg, Hauts-de-France, Illinois, Latium, Maryland, Massachusetts, Nord-Pas-de-Calais, Nouvelle-Aquitaine, Nouvelle-Galles du Sud, Ontario, Oxfordshire, Pennsylvanie, Rhénanie-Palatinat, Schleswig-Holstein, Tennessee, Texas, Tyrol (Land), Washington (État), Wisconsin, Écosse, État de New York
- Berne, Bordeaux, Cambridge, Fribourg-en-Brisgau, Groningue, Hambourg, Hanovre, Heidelberg, Innsbruck, Kiel, Lausanne, Lille, Mannheim, Mayence, Munich, Oxford, Rome, Sydney, Toronto, Ulm, Zurich, Édimbourg
- Université d'Oxford, Université d'Édimbourg, Université de Cambridge, Université de Sydney, Université de Toronto, Université de Zurich, Université de médecine d'Innsbruck, Université technique de Munich
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Le document en format XML
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<author><name sortKey="Luciani, Alessandro" sort="Luciani, Alessandro" uniqKey="Luciani A" first="Alessandro" last="Luciani">Alessandro Luciani</name>
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<author><name sortKey="Chen, Ming Huei" sort="Chen, Ming Huei" uniqKey="Chen M" first="Ming-Huei" last="Chen">Ming-Huei Chen</name>
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<affiliation wicri:level="2"><nlm:aff id="aff16">Department of Biostatistics, Boston University School of Public Health, Boston, MA</nlm:aff>
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<author><name sortKey="Yang, Qiong" sort="Yang, Qiong" uniqKey="Yang Q" first="Qiong" last="Yang">Qiong Yang</name>
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<author><name sortKey="Foster, Meredith C" sort="Foster, Meredith C" uniqKey="Foster M" first="Meredith C." last="Foster">Meredith C. Foster</name>
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<author><name sortKey="Olden, Matthias" sort="Olden, Matthias" uniqKey="Olden M" first="Matthias" last="Olden">Matthias Olden</name>
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<author><name sortKey="Hiraki, Linda T" sort="Hiraki, Linda T" uniqKey="Hiraki L" first="Linda T." last="Hiraki">Linda T. Hiraki</name>
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<author><name sortKey="Tayo, Bamidele O" sort="Tayo, Bamidele O" uniqKey="Tayo B" first="Bamidele O." last="Tayo">Bamidele O. Tayo</name>
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<wicri:cityArea>Loyola University Chicago, Maywood</wicri:cityArea>
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<author><name sortKey="Fuchsberger, Christian" sort="Fuchsberger, Christian" uniqKey="Fuchsberger C" first="Christian" last="Fuchsberger">Christian Fuchsberger</name>
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<country xml:lang="fr">Italie</country>
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<author><name sortKey="Dieffenbach, Aida Karina" sort="Dieffenbach, Aida Karina" uniqKey="Dieffenbach A" first="Aida Karina" last="Dieffenbach">Aida Karina Dieffenbach</name>
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<affiliation wicri:level="3"><nlm:aff id="aff22">German Cancer Consortium (DKTK), Heidelberg, Germany</nlm:aff>
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<author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R." last="Shuldiner">Alan R. Shuldiner</name>
<affiliation wicri:level="2"><nlm:aff id="aff23">Department of Medicine, University of Maryland School of Medicine, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
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<wicri:cityArea>Department of Medicine, University of Maryland School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V." last="Smith">Albert V. Smith</name>
<affiliation wicri:level="1"><nlm:aff id="aff24">Icelandic Heart Association, Kópavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kópavogur</wicri:regionArea>
<wicri:noRegion>Kópavogur</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25">Faculty of Medicine, University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea>
<wicri:noRegion>Reykjavik</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zappa, Allison M" sort="Zappa, Allison M" uniqKey="Zappa A" first="Allison M." last="Zappa">Allison M. Zappa</name>
<affiliation wicri:level="2"><nlm:aff id="aff26">Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Lupo, Antonio" sort="Lupo, Antonio" uniqKey="Lupo A" first="Antonio" last="Lupo">Antonio Lupo</name>
<affiliation wicri:level="1"><nlm:aff id="aff27">Renal Unit, Department of Medicine, University of Verona, Verona, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Renal Unit, Department of Medicine, University of Verona, Verona</wicri:regionArea>
<wicri:noRegion>Verona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kollerits, Barbara" sort="Kollerits, Barbara" uniqKey="Kollerits B" first="Barbara" last="Kollerits">Barbara Kollerits</name>
<affiliation wicri:level="4"><nlm:aff id="aff28">Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck</wicri:regionArea>
<orgName type="university">Université de médecine d'Innsbruck</orgName>
<placeName><settlement type="city">Innsbruck</settlement>
<region nuts="2" type="region">Tyrol (Land)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ponte, Belen" sort="Ponte, Belen" uniqKey="Ponte B" first="Belen" last="Ponte">Belen Ponte</name>
<affiliation wicri:level="1"><nlm:aff id="aff29">Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospitals, Geneva, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospitals, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stengel, Benedicte" sort="Stengel, Benedicte" uniqKey="Stengel B" first="Bénédicte" last="Stengel">Bénédicte Stengel</name>
<affiliation wicri:level="1"><nlm:aff id="aff30">INSERM U-1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U-1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Villejuif</wicri:regionArea>
<wicri:noRegion>Villejuif</wicri:noRegion>
<wicri:noRegion>Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31">UMRS 1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Univ Paris Sud, Univ Versailles, St. Quentin, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>UMRS 1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Univ Paris Sud, Univ Versailles, St. Quentin</wicri:regionArea>
<wicri:noRegion>St. Quentin</wicri:noRegion>
<wicri:noRegion>St. Quentin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kr Mer, Bernhard K" sort="Kr Mer, Bernhard K" uniqKey="Kr Mer B" first="Bernhard K." last="Kr Mer">Bernhard K. Kr Mer</name>
<affiliation wicri:level="3"><nlm:aff id="aff32">Fifth Department of Medicine, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Fifth Department of Medicine, University Medical Centre Mannheim, University of Heidelberg, Mannheim</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Mannheim</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Paulweber, Bernhard" sort="Paulweber, Bernhard" uniqKey="Paulweber B" first="Bernhard" last="Paulweber">Bernhard Paulweber</name>
<affiliation wicri:level="1"><nlm:aff id="aff33">First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Salzburg, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Salzburg</wicri:regionArea>
<wicri:noRegion>Salzburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mitchell, Braxton D" sort="Mitchell, Braxton D" uniqKey="Mitchell B" first="Braxton D." last="Mitchell">Braxton D. Mitchell</name>
<affiliation wicri:level="2"><nlm:aff id="aff23">Department of Medicine, University of Maryland School of Medicine, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Medicine, University of Maryland School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name>
<affiliation wicri:level="4"><nlm:aff id="aff34">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland</wicri:regionArea>
<orgName type="university">Université d'Édimbourg</orgName>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Helmer, Catherine" sort="Helmer, Catherine" uniqKey="Helmer C" first="Catherine" last="Helmer">Catherine Helmer</name>
<affiliation wicri:level="3"><nlm:aff id="aff35">INSERM U897, Bordeaux University, Institut de Santé Publique, d'Epidémiologie et de Développement (ISPED), Bordeaux, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U897, Bordeaux University, Institut de Santé Publique, d'Epidémiologie et de Développement (ISPED), Bordeaux</wicri:regionArea>
<placeName><region type="region">Nouvelle-Aquitaine</region>
<region type="old region">Aquitaine</region>
<settlement type="city">Bordeaux</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Meisinger, Christa" sort="Meisinger, Christa" uniqKey="Meisinger C" first="Christa" last="Meisinger">Christa Meisinger</name>
<affiliation wicri:level="1"><nlm:aff id="aff36">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name>
<affiliation wicri:level="1"><nlm:aff id="aff37">Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shaffer, Christian M" sort="Shaffer, Christian M" uniqKey="Shaffer C" first="Christian M." last="Shaffer">Christian M. Shaffer</name>
<affiliation wicri:level="2"><nlm:aff id="aff38">Vanderbilt University School of Medicine, Nashville, TN</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Vanderbilt University School of Medicine, Nashville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Muller, Christian" sort="Muller, Christian" uniqKey="Muller C" first="Christian" last="Müller">Christian Müller</name>
<affiliation wicri:level="3"><nlm:aff id="aff39">University Heart Center Hamburg, Hamburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>University Heart Center Hamburg, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff40">German Center for Cardiovascular Research (DZHK e.V.), partner site Hamburg, Lübeck, Kiel, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK e.V.), partner site Hamburg, Lübeck, Kiel</wicri:regionArea>
<placeName><region type="land" nuts="2">Schleswig-Holstein</region>
<settlement type="city">Kiel</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff41">Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ackermann, Daniel" sort="Ackermann, Daniel" uniqKey="Ackermann D" first="Daniel" last="Ackermann">Daniel Ackermann</name>
<affiliation wicri:level="3"><nlm:aff id="aff42">University Clinic for Nephrology, Hypertension and Clinical Pharmacology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>University Clinic for Nephrology, Hypertension and Clinical Pharmacology, Inselspital, Bern University Hospital and University of Bern, Bern</wicri:regionArea>
<placeName><settlement type="city">Berne</settlement>
<region type="région" nuts="3">Canton de Berne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Siscovick, David" sort="Siscovick, David" uniqKey="Siscovick D" first="David" last="Siscovick">David Siscovick</name>
<affiliation wicri:level="2"><nlm:aff id="aff43">Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, Seattle</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name>
<affiliation wicri:level="2"><nlm:aff id="aff45">Human Genetics Center, University of Texas Health Science Center, Houston, TX</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Texas</region>
</placeName>
<wicri:cityArea>Human Genetics Center, University of Texas Health Science Center, Houston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Kronenberg, Florian" sort="Kronenberg, Florian" uniqKey="Kronenberg F" first="Florian" last="Kronenberg">Florian Kronenberg</name>
<affiliation wicri:level="4"><nlm:aff id="aff28">Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck</wicri:regionArea>
<orgName type="university">Université de médecine d'Innsbruck</orgName>
<placeName><settlement type="city">Innsbruck</settlement>
<region nuts="2" type="region">Tyrol (Land)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ehret, Georg B" sort="Ehret, Georg B" uniqKey="Ehret G" first="Georg B." last="Ehret">Georg B. Ehret</name>
<affiliation wicri:level="1"><nlm:aff id="aff46">Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospitals, Geneva, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospitals, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name>
<affiliation wicri:level="1"><nlm:aff id="aff47">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Waeber, Gerard" sort="Waeber, Gerard" uniqKey="Waeber G" first="Gerard" last="Waeber">Gerard Waeber</name>
<affiliation wicri:level="3"><nlm:aff id="aff48">Department of Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Internal Medicine, Lausanne University Hospital, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Navis, Gerjan" sort="Navis, Gerjan" uniqKey="Navis G" first="Gerjan" last="Navis">Gerjan Navis</name>
<affiliation wicri:level="3"><nlm:aff id="aff49">Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gambaro, Giovanni" sort="Gambaro, Giovanni" uniqKey="Gambaro G" first="Giovanni" last="Gambaro">Giovanni Gambaro</name>
<affiliation wicri:level="3"><nlm:aff id="aff50">Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus-Gemelli University Hospital, Catholic University, Rome, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus-Gemelli University Hospital, Catholic University, Rome</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Malerba, Giovanni" sort="Malerba, Giovanni" uniqKey="Malerba G" first="Giovanni" last="Malerba">Giovanni Malerba</name>
<affiliation wicri:level="1"><nlm:aff id="aff11">Department of Life and Reproduction Sciences, University of Verona, Verona, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Life and Reproduction Sciences, University of Verona, Verona</wicri:regionArea>
<wicri:noRegion>Verona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name>
<affiliation wicri:level="1"><nlm:aff id="aff24">Icelandic Heart Association, Kópavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kópavogur</wicri:regionArea>
<wicri:noRegion>Kópavogur</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Li, Guo" sort="Li, Guo" uniqKey="Li G" first="Guo" last="Li">Guo Li</name>
<affiliation wicri:level="2"><nlm:aff id="aff43">Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, Seattle</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H. Erich" last="Wichmann">H. Erich Wichmann</name>
<affiliation wicri:level="1"><nlm:aff id="aff51">Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff52">Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff53">Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name>
<affiliation wicri:level="1"><nlm:aff id="aff36">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff54">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff55">German Center for Diabetes Research (DZD), Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Diabetes Research (DZD), Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wallaschofski, Henri" sort="Wallaschofski, Henri" uniqKey="Wallaschofski H" first="Henri" last="Wallaschofski">Henri Wallaschofski</name>
<affiliation wicri:level="1"><nlm:aff id="aff56">Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2">German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Brenner, Herrmann" sort="Brenner, Herrmann" uniqKey="Brenner H" first="Herrmann" last="Brenner">Herrmann Brenner</name>
<affiliation wicri:level="3"><nlm:aff id="aff21">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kramer, Holly" sort="Kramer, Holly" uniqKey="Kramer H" first="Holly" last="Kramer">Holly Kramer</name>
<affiliation wicri:level="2"><nlm:aff id="aff20">Loyola University Chicago, Maywood, IL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Illinois</region>
</placeName>
<wicri:cityArea>Loyola University Chicago, Maywood</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Leach, I Mateo" sort="Leach, I Mateo" uniqKey="Leach I" first="I. Mateo" last="Leach">I. Mateo Leach</name>
<affiliation wicri:level="3"><nlm:aff id="aff57">Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name>
<affiliation wicri:level="4"><nlm:aff id="aff58">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland</wicri:regionArea>
<orgName type="university">Université d'Édimbourg</orgName>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hillege, Hans L" sort="Hillege, Hans L" uniqKey="Hillege H" first="Hans L." last="Hillege">Hans L. Hillege</name>
<affiliation wicri:level="3"><nlm:aff id="aff59">Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S." last="Beckmann">Jacques S. Beckmann</name>
<affiliation wicri:level="3"><nlm:aff id="aff60">Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff61">Swiss Institute of Bioinformatics, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lambert, Jean Charles" sort="Lambert, Jean Charles" uniqKey="Lambert J" first="Jean Charles" last="Lambert">Jean Charles Lambert</name>
<affiliation wicri:level="3"><nlm:aff id="aff62">INSERM UMR 1167 “Risk factors and molecular determinants of aging-related diseases,” Institut Pasteur de Lille, Lille, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>INSERM UMR 1167 “Risk factors and molecular determinants of aging-related diseases,” Institut Pasteur de Lille, Lille</wicri:regionArea>
<placeName><region type="region">Hauts-de-France</region>
<region type="old region">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Luan, Jian An" sort="Luan, Jian An" uniqKey="Luan J" first="Jian'An" last="Luan">Jian'An Luan</name>
<affiliation wicri:level="1"><nlm:aff id="aff41">Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name>
<affiliation wicri:level="1"><nlm:aff id="aff41">Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chalmers, John" sort="Chalmers, John" uniqKey="Chalmers J" first="John" last="Chalmers">John Chalmers</name>
<affiliation wicri:level="4"><nlm:aff id="aff63">The George Institute for Global Health, University of Sydney, Camperdown, New South Wales, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>The George Institute for Global Health, University of Sydney, Camperdown, New South Wales</wicri:regionArea>
<orgName type="university">Université de Sydney</orgName>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Coresh, Josef" sort="Coresh, Josef" uniqKey="Coresh J" first="Josef" last="Coresh">Josef Coresh</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff64">Welch Center for Prevention, Epidemiology and Clinical Research, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Welch Center for Prevention, Epidemiology and Clinical Research, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Denny, Joshua C" sort="Denny, Joshua C" uniqKey="Denny J" first="Joshua C." last="Denny">Joshua C. Denny</name>
<affiliation wicri:level="2"><nlm:aff id="aff65">Vanderbilt University School of Medicine, Nashville, TN</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Vanderbilt University School of Medicine, Nashville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Butterbach, Katja" sort="Butterbach, Katja" uniqKey="Butterbach K" first="Katja" last="Butterbach">Katja Butterbach</name>
<affiliation wicri:level="3"><nlm:aff id="aff21">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J." last="Launer">Lenore J. Launer</name>
<affiliation wicri:level="2"><nlm:aff id="aff66">Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name>
<affiliation wicri:level="2"><nlm:aff id="aff67">Clinical Research Branch, National Institute on Aging, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Clinical Research Branch, National Institute on Aging, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Kedenko, Lyudmyla" sort="Kedenko, Lyudmyla" uniqKey="Kedenko L" first="Lyudmyla" last="Kedenko">Lyudmyla Kedenko</name>
<affiliation wicri:level="1"><nlm:aff id="aff33">First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Salzburg, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Salzburg</wicri:regionArea>
<wicri:noRegion>Salzburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Haun, Margot" sort="Haun, Margot" uniqKey="Haun M" first="Margot" last="Haun">Margot Haun</name>
<affiliation wicri:level="4"><nlm:aff id="aff28">Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck</wicri:regionArea>
<orgName type="university">Université de médecine d'Innsbruck</orgName>
<placeName><settlement type="city">Innsbruck</settlement>
<region nuts="2" type="region">Tyrol (Land)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Metzger, Marie" sort="Metzger, Marie" uniqKey="Metzger M" first="Marie" last="Metzger">Marie Metzger</name>
<affiliation wicri:level="1"><nlm:aff id="aff30">INSERM U-1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U-1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Villejuif</wicri:regionArea>
<wicri:noRegion>Villejuif</wicri:noRegion>
<wicri:noRegion>Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31">UMRS 1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Univ Paris Sud, Univ Versailles, St. Quentin, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>UMRS 1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Univ Paris Sud, Univ Versailles, St. Quentin</wicri:regionArea>
<wicri:noRegion>St. Quentin</wicri:noRegion>
<wicri:noRegion>St. Quentin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Woodward, Mark" sort="Woodward, Mark" uniqKey="Woodward M" first="Mark" last="Woodward">Mark Woodward</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff63">The George Institute for Global Health, University of Sydney, Camperdown, New South Wales, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>The George Institute for Global Health, University of Sydney, Camperdown, New South Wales</wicri:regionArea>
<orgName type="university">Université de Sydney</orgName>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff68">The George Institute for Global Health, Nuffield Department of Population Health, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>The George Institute for Global Health, Nuffield Department of Population Health, University of Oxford, Oxford</wicri:regionArea>
<placeName><settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author><name sortKey="Hoffman, Matthew J" sort="Hoffman, Matthew J" uniqKey="Hoffman M" first="Matthew J." last="Hoffman">Matthew J. Hoffman</name>
<affiliation wicri:level="2"><nlm:aff id="aff7">Department of Physiology, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Department of Physiology, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Nauck, Matthias" sort="Nauck, Matthias" uniqKey="Nauck M" first="Matthias" last="Nauck">Matthias Nauck</name>
<affiliation wicri:level="1"><nlm:aff id="aff2">German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff56">Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name>
<affiliation wicri:level="1"><nlm:aff id="aff36">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pruijm, Menno" sort="Pruijm, Menno" uniqKey="Pruijm M" first="Menno" last="Pruijm">Menno Pruijm</name>
<affiliation wicri:level="3"><nlm:aff id="aff69">Service of Nephrology, Lausanne University Hospital, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Service of Nephrology, Lausanne University Hospital, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bochud, Murielle" sort="Bochud, Murielle" uniqKey="Bochud M" first="Murielle" last="Bochud">Murielle Bochud</name>
<affiliation wicri:level="1"><nlm:aff id="aff70">University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Épalinges, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Épalinges</wicri:regionArea>
<wicri:noRegion>Épalinges</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rheinberger, Myriam" sort="Rheinberger, Myriam" uniqKey="Rheinberger M" first="Myriam" last="Rheinberger">Myriam Rheinberger</name>
<affiliation wicri:level="1"><nlm:aff id="aff71">Department of Nephrology, University Hospital Regensburg, Regensburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Nephrology, University Hospital Regensburg, Regensburg</wicri:regionArea>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name>
<affiliation wicri:level="3"><nlm:aff id="aff57">Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J." last="Wareham">Nicholas J. Wareham</name>
<affiliation wicri:level="1"><nlm:aff id="aff41">Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Endlich, Nicole" sort="Endlich, Nicole" uniqKey="Endlich N" first="Nicole" last="Endlich">Nicole Endlich</name>
<affiliation wicri:level="1"><nlm:aff id="aff72">Institute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Soranzo, Nicole" sort="Soranzo, Nicole" uniqKey="Soranzo N" first="Nicole" last="Soranzo">Nicole Soranzo</name>
<affiliation wicri:level="1"><nlm:aff id="aff73">Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Human Genetics, Wellcome Trust Sanger Institute, Hinxton</wicri:regionArea>
<wicri:noRegion>Hinxton</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff74">Department of Haematology, University of Cambridge, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Haematology, University of Cambridge, Cambridge</wicri:regionArea>
<orgName type="university">Université de Cambridge</orgName>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name>
<affiliation wicri:level="1"><nlm:aff id="aff75">Croatian Centre for Global Health, Faculty of Medicine, University of Split, Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Croatian Centre for Global Health, Faculty of Medicine, University of Split, Split</wicri:regionArea>
<wicri:noRegion>Split</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name>
<affiliation wicri:level="3"><nlm:aff id="aff59">Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pramstaller, Peter Paul" sort="Pramstaller, Peter Paul" uniqKey="Pramstaller P" first="Peter Paul" last="Pramstaller">Peter Paul Pramstaller</name>
<affiliation wicri:level="1"><nlm:aff id="aff13">Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano</wicri:regionArea>
<wicri:noRegion>Bolzano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name>
<affiliation wicri:level="3"><nlm:aff id="aff48">Department of Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Internal Medicine, Lausanne University Hospital, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wild, Philipp S" sort="Wild, Philipp S" uniqKey="Wild P" first="Philipp S." last="Wild">Philipp S. Wild</name>
<affiliation wicri:level="3"><nlm:aff id="aff76">Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg, University Mainz, Mainz</wicri:regionArea>
<placeName><region type="land" nuts="2">Rhénanie-Palatinat</region>
<settlement type="city">Mayence</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff77">Preventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Preventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz</wicri:regionArea>
<placeName><region type="land" nuts="2">Rhénanie-Palatinat</region>
<settlement type="city">Mayence</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff78">German Center for Cardiovascular Research (DZHK), Mainz, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK), Mainz</wicri:regionArea>
<placeName><region type="land" nuts="2">Rhénanie-Palatinat</region>
<settlement type="city">Mayence</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gansevoort, Ron T" sort="Gansevoort, Ron T" uniqKey="Gansevoort R" first="Ron T." last="Gansevoort">Ron T. Gansevoort</name>
<affiliation wicri:level="3"><nlm:aff id="aff59">Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rettig, Rainer" sort="Rettig, Rainer" uniqKey="Rettig R" first="Rainer" last="Rettig">Rainer Rettig</name>
<affiliation wicri:level="1"><nlm:aff id="aff79">Institute of Physiology, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Physiology, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Biffar, Reiner" sort="Biffar, Reiner" uniqKey="Biffar R" first="Reiner" last="Biffar">Reiner Biffar</name>
<affiliation wicri:level="1"><nlm:aff id="aff80">Clinic for Prosthetic Dentistry, Gerostomatology and Material Science, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Clinic for Prosthetic Dentistry, Gerostomatology and Material Science, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Carroll, Robert J" sort="Carroll, Robert J" uniqKey="Carroll R" first="Robert J." last="Carroll">Robert J. Carroll</name>
<affiliation wicri:level="2"><nlm:aff id="aff65">Vanderbilt University School of Medicine, Nashville, TN</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Vanderbilt University School of Medicine, Nashville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Katz, Ronit" sort="Katz, Ronit" uniqKey="Katz R" first="Ronit" last="Katz">Ronit Katz</name>
<affiliation wicri:level="2"><nlm:aff id="aff81">Kidney Research Institute, Department of Medicine, University of Washington, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Kidney Research Institute, Department of Medicine, University of Washington, Seattle</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J. F." last="Loos">Ruth J. F. Loos</name>
<affiliation wicri:level="1"><nlm:aff id="aff41">Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff82">Genetics of Obesity and Related Metabolic Traits Program, The Charles Bronfman Institute for Personalized Medicine, The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Genetics of Obesity and Related Metabolic Traits Program, The Charles Bronfman Institute for Personalized Medicine, The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name>
<affiliation wicri:level="2"><nlm:aff id="aff9">National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Coassin, Stefan" sort="Coassin, Stefan" uniqKey="Coassin S" first="Stefan" last="Coassin">Stefan Coassin</name>
<affiliation wicri:level="4"><nlm:aff id="aff28">Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck</wicri:regionArea>
<orgName type="university">Université de médecine d'Innsbruck</orgName>
<placeName><settlement type="city">Innsbruck</settlement>
<region nuts="2" type="region">Tyrol (Land)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bergmann, Sven" sort="Bergmann, Sven" uniqKey="Bergmann S" first="Sven" last="Bergmann">Sven Bergmann</name>
<affiliation wicri:level="3"><nlm:aff id="aff83">Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rosas, Sylvia E" sort="Rosas, Sylvia E" uniqKey="Rosas S" first="Sylvia E." last="Rosas">Sylvia E. Rosas</name>
<affiliation wicri:level="2"><nlm:aff id="aff84">Kidney and Hypertension Section, Joslin Diabetes Center and Harvard Medical School, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Kidney and Hypertension Section, Joslin Diabetes Center and Harvard Medical School, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Stracke, Sylvia" sort="Stracke, Sylvia" uniqKey="Stracke S" first="Sylvia" last="Stracke">Sylvia Stracke</name>
<affiliation wicri:level="1"><nlm:aff id="aff85">Clinic for Internal Medicine A, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Clinic for Internal Medicine A, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B." last="Harris">Tamara B. Harris</name>
<affiliation wicri:level="2"><nlm:aff id="aff66">Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Corre, Tanguy" sort="Corre, Tanguy" uniqKey="Corre T" first="Tanguy" last="Corre">Tanguy Corre</name>
<affiliation wicri:level="3"><nlm:aff id="aff83">Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zeller, Tanja" sort="Zeller, Tanja" uniqKey="Zeller T" first="Tanja" last="Zeller">Tanja Zeller</name>
<affiliation wicri:level="3"><nlm:aff id="aff39">University Heart Center Hamburg, Hamburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>University Heart Center Hamburg, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff40">German Center for Cardiovascular Research (DZHK e.V.), partner site Hamburg, Lübeck, Kiel, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK e.V.), partner site Hamburg, Lübeck, Kiel</wicri:regionArea>
<placeName><region type="land" nuts="2">Schleswig-Holstein</region>
<settlement type="city">Kiel</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name>
<affiliation wicri:level="1"><nlm:aff id="aff36">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff86">Institute for Human Genetics, Hannover Medical School, Hannover, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute for Human Genetics, Hannover Medical School, Hannover</wicri:regionArea>
<placeName><region type="land" nuts="2">Basse-Saxe</region>
<settlement type="city">Hanovre</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff87">Hannover Unified Biobank, Hannover Medical School, Hannover, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Hannover Unified Biobank, Hannover Medical School, Hannover</wicri:regionArea>
<placeName><region type="land" nuts="2">Basse-Saxe</region>
<settlement type="city">Hanovre</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Aspelund, Thor" sort="Aspelund, Thor" uniqKey="Aspelund T" first="Thor" last="Aspelund">Thor Aspelund</name>
<affiliation wicri:level="1"><nlm:aff id="aff24">Icelandic Heart Association, Kópavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kópavogur</wicri:regionArea>
<wicri:noRegion>Kópavogur</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25">Faculty of Medicine, University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea>
<wicri:noRegion>Reykjavik</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name>
<affiliation wicri:level="2"><nlm:aff id="aff67">Clinical Research Branch, National Institute on Aging, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Clinical Research Branch, National Institute on Aging, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Lendeckel, Uwe" sort="Lendeckel, Uwe" uniqKey="Lendeckel U" first="Uwe" last="Lendeckel">Uwe Lendeckel</name>
<affiliation wicri:level="1"><nlm:aff id="aff88">Institute of Medical Biochemistry and Molecular Biology, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Medical Biochemistry and Molecular Biology, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name>
<affiliation wicri:level="1"><nlm:aff id="aff2">German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff47">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name>
<affiliation wicri:level="1"><nlm:aff id="aff24">Icelandic Heart Association, Kópavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kópavogur</wicri:regionArea>
<wicri:noRegion>Kópavogur</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25">Faculty of Medicine, University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea>
<wicri:noRegion>Reykjavik</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chouraki, Vincent" sort="Chouraki, Vincent" uniqKey="Chouraki V" first="Vincent" last="Chouraki">Vincent Chouraki</name>
<affiliation wicri:level="3"><nlm:aff id="aff62">INSERM UMR 1167 “Risk factors and molecular determinants of aging-related diseases,” Institut Pasteur de Lille, Lille, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>INSERM UMR 1167 “Risk factors and molecular determinants of aging-related diseases,” Institut Pasteur de Lille, Lille</wicri:regionArea>
<placeName><region type="region">Hauts-de-France</region>
<region type="old region">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name>
<affiliation wicri:level="3"><nlm:aff id="aff89">Abteilung Innere II, Universitätsklinikum Ulm, Ulm, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Abteilung Innere II, Universitätsklinikum Ulm, Ulm</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Ulm</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff90">Deutsches Herzzentrum München, Technische Universität München, Munich, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Deutsches Herzzentrum München, Technische Universität München, Munich</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
<settlement type="city">Munich</settlement>
</placeName>
<orgName type="university">Université technique de Munich</orgName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff91">German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kutalik, Zoltan" sort="Kutalik, Zoltan" uniqKey="Kutalik Z" first="Zoltan" last="Kutalik">Zoltan Kutalik</name>
<affiliation wicri:level="3"><nlm:aff id="aff61">Swiss Institute of Bioinformatics, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff83">Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff92">University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="O Connell, Jeffrey R" sort="O Connell, Jeffrey R" uniqKey="O Connell J" first="Jeffrey R." last="O'Connell">Jeffrey R. O'Connell</name>
<affiliation wicri:level="2"><nlm:aff id="aff23">Department of Medicine, University of Maryland School of Medicine, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Medicine, University of Maryland School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Parsa, Afshin" sort="Parsa, Afshin" uniqKey="Parsa A" first="Afshin" last="Parsa">Afshin Parsa</name>
<affiliation wicri:level="2"><nlm:aff id="aff23">Department of Medicine, University of Maryland School of Medicine, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Medicine, University of Maryland School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Heid, Iris M" sort="Heid, Iris M" uniqKey="Heid I" first="Iris M." last="Heid">Iris M. Heid</name>
<affiliation wicri:level="1"><nlm:aff id="aff5">Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg</wicri:regionArea>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff37">Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Paterson, Andrew D" sort="Paterson, Andrew D" uniqKey="Paterson A" first="Andrew D." last="Paterson">Andrew D. Paterson</name>
<affiliation wicri:level="1"><nlm:aff id="aff19">Genetics and Genome Biology Program, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Genetics and Genome Biology Program, The Hospital for Sick Children Research Institute, Toronto, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff93">Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="De Boer, Ian H" sort="De Boer, Ian H" uniqKey="De Boer I" first="Ian H." last="De Boer">Ian H. De Boer</name>
<affiliation wicri:level="2"><nlm:aff id="aff81">Kidney Research Institute, Department of Medicine, University of Washington, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Kidney Research Institute, Department of Medicine, University of Washington, Seattle</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Devuyst, Olivier" sort="Devuyst, Olivier" uniqKey="Devuyst O" first="Olivier" last="Devuyst">Olivier Devuyst</name>
<affiliation wicri:level="4"><nlm:aff id="aff14">Institute of Physiology, Mechanisms of Inherited Kidney Disorders Group, University of Zürich, Zürich, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Institute of Physiology, Mechanisms of Inherited Kidney Disorders Group, University of Zürich, Zürich</wicri:regionArea>
<placeName><settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
<settlement type="city">Zurich</settlement>
</placeName>
<orgName type="university">Université de Zurich</orgName>
</affiliation>
</author>
<author><name sortKey="Lazar, Jozef" sort="Lazar, Jozef" uniqKey="Lazar J" first="Jozef" last="Lazar">Jozef Lazar</name>
<affiliation wicri:level="2"><nlm:aff id="aff94">Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Department of Dermatology, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
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<wicri:regionArea>Institute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald</wicri:regionArea>
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<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
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<author><name sortKey="Susztak, Katalin" sort="Susztak, Katalin" uniqKey="Susztak K" first="Katalin" last="Susztak">Katalin Susztak</name>
<affiliation wicri:level="2"><nlm:aff id="aff12">Renal-Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, PA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Renal-Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Tremblay, Johanne" sort="Tremblay, Johanne" uniqKey="Tremblay J" first="Johanne" last="Tremblay">Johanne Tremblay</name>
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<wicri:regionArea>Centre de Recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), University of Montreal, CHUM Research Center, Technopìle Angus, Montreal, Quebec</wicri:regionArea>
<wicri:noRegion>Quebec</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hamet, Pavel" sort="Hamet, Pavel" uniqKey="Hamet P" first="Pavel" last="Hamet">Pavel Hamet</name>
<affiliation wicri:level="1"><nlm:aff id="aff95">Centre de Recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), University of Montreal, CHUM Research Center, Technopìle Angus, Montreal, Quebec, Canada.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Canada</country>
<wicri:regionArea>Centre de Recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), University of Montreal, CHUM Research Center, Technopìle Angus, Montreal, Quebec</wicri:regionArea>
<wicri:noRegion>Quebec</wicri:noRegion>
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<author><name sortKey="Jacob, Howard J" sort="Jacob, Howard J" uniqKey="Jacob H" first="Howard J." last="Jacob">Howard J. Jacob</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Department of Physiology, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Boger, Carsten A" sort="Boger, Carsten A" uniqKey="Boger C" first="Carsten A." last="Böger">Carsten A. Böger</name>
<affiliation wicri:level="1"><nlm:aff id="aff6">Department of Nephrology, University Hospital Regensburg, Regensburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Nephrology, University Hospital Regensburg, Regensburg</wicri:regionArea>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
</affiliation>
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<author><name sortKey="Fox, Caroline S" sort="Fox, Caroline S" uniqKey="Fox C" first="Caroline S." last="Fox">Caroline S. Fox</name>
<affiliation wicri:level="2"><nlm:aff id="aff9">National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff96">Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston</wicri:cityArea>
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</author>
<author><name sortKey="Pattaro, Cristian" sort="Pattaro, Cristian" uniqKey="Pattaro C" first="Cristian" last="Pattaro">Cristian Pattaro</name>
<affiliation wicri:level="1"><nlm:aff id="aff13">Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano</wicri:regionArea>
<wicri:noRegion>Bolzano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kottgen, Anna" sort="Kottgen, Anna" uniqKey="Kottgen A" first="Anna" last="Köttgen">Anna Köttgen</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff10">Renal Division, Medical Center, University of Freiburg, Freiburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Renal Division, Medical Center, University of Freiburg, Freiburg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Fribourg-en-Brisgau</region>
<settlement type="city">Fribourg-en-Brisgau</settlement>
</placeName>
</affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes</title>
<author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2">German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tin, Adrienne" sort="Tin, Adrienne" uniqKey="Tin A" first="Adrienne" last="Tin">Adrienne Tin</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Sorice, Rossella" sort="Sorice, Rossella" uniqKey="Sorice R" first="Rossella" last="Sorice">Rossella Sorice</name>
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<country xml:lang="fr">Italie</country>
<wicri:regionArea>Institute of Genetics and Biophysics, “Adriano-Buzzati Traverso,” Consiglio Nazionale delle Ricerche, Naples</wicri:regionArea>
<wicri:noRegion>Naples</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gorski, Mathias" sort="Gorski, Mathias" uniqKey="Gorski M" first="Mathias" last="Gorski">Mathias Gorski</name>
<affiliation wicri:level="1"><nlm:aff id="aff5">Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg</wicri:regionArea>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff6">Department of Nephrology, University Hospital Regensburg, Regensburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Nephrology, University Hospital Regensburg, Regensburg</wicri:regionArea>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Yeo, Nan Cher" sort="Yeo, Nan Cher" uniqKey="Yeo N" first="Nan Cher" last="Yeo">Nan Cher Yeo</name>
<affiliation wicri:level="2"><nlm:aff id="aff7">Department of Physiology, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Department of Physiology, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Chu, Audrey Y" sort="Chu, Audrey Y" uniqKey="Chu A" first="Audrey Y." last="Chu">Audrey Y. Chu</name>
<affiliation wicri:level="2"><nlm:aff id="aff8">Preventive Medicine, Brigham and Women's Hospital, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Preventive Medicine, Brigham and Women's Hospital, Boston</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff9">National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Li, Man" sort="Li, Man" uniqKey="Li M" first="Man" last="Li">Man Li</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Li, Yong" sort="Li, Yong" uniqKey="Li Y" first="Yong" last="Li">Yong Li</name>
<affiliation wicri:level="3"><nlm:aff id="aff10">Renal Division, Medical Center, University of Freiburg, Freiburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Renal Division, Medical Center, University of Freiburg, Freiburg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Fribourg-en-Brisgau</region>
<settlement type="city">Fribourg-en-Brisgau</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mijatovic, Vladan" sort="Mijatovic, Vladan" uniqKey="Mijatovic V" first="Vladan" last="Mijatovic">Vladan Mijatovic</name>
<affiliation wicri:level="1"><nlm:aff id="aff11">Department of Life and Reproduction Sciences, University of Verona, Verona, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Life and Reproduction Sciences, University of Verona, Verona</wicri:regionArea>
<wicri:noRegion>Verona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ko, Yi An" sort="Ko, Yi An" uniqKey="Ko Y" first="Yi-An" last="Ko">Yi-An Ko</name>
<affiliation wicri:level="2"><nlm:aff id="aff12">Renal-Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, PA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Renal-Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Taliun, Daniel" sort="Taliun, Daniel" uniqKey="Taliun D" first="Daniel" last="Taliun">Daniel Taliun</name>
<affiliation wicri:level="1"><nlm:aff id="aff13">Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano</wicri:regionArea>
<wicri:noRegion>Bolzano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Luciani, Alessandro" sort="Luciani, Alessandro" uniqKey="Luciani A" first="Alessandro" last="Luciani">Alessandro Luciani</name>
<affiliation wicri:level="4"><nlm:aff id="aff14">Institute of Physiology, Mechanisms of Inherited Kidney Disorders Group, University of Zürich, Zürich, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Institute of Physiology, Mechanisms of Inherited Kidney Disorders Group, University of Zürich, Zürich</wicri:regionArea>
<placeName><settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
<settlement type="city">Zurich</settlement>
</placeName>
<orgName type="university">Université de Zurich</orgName>
</affiliation>
</author>
<author><name sortKey="Chen, Ming Huei" sort="Chen, Ming Huei" uniqKey="Chen M" first="Ming-Huei" last="Chen">Ming-Huei Chen</name>
<affiliation wicri:level="2"><nlm:aff id="aff15">Department of Neurology, Boston University School of Medicine, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Neurology, Boston University School of Medicine, Boston</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff16">Department of Biostatistics, Boston University School of Public Health, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Biostatistics, Boston University School of Public Health, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Yang, Qiong" sort="Yang, Qiong" uniqKey="Yang Q" first="Qiong" last="Yang">Qiong Yang</name>
<affiliation wicri:level="2"><nlm:aff id="aff16">Department of Biostatistics, Boston University School of Public Health, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Biostatistics, Boston University School of Public Health, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Foster, Meredith C" sort="Foster, Meredith C" uniqKey="Foster M" first="Meredith C." last="Foster">Meredith C. Foster</name>
<affiliation wicri:level="2"><nlm:aff id="aff17">Tufts Medical Center, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Tufts Medical Center, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Olden, Matthias" sort="Olden, Matthias" uniqKey="Olden M" first="Matthias" last="Olden">Matthias Olden</name>
<affiliation wicri:level="1"><nlm:aff id="aff5">Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg</wicri:regionArea>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff18">Department of Epidemiology and Preventive Medicine, Regensburg University Medical Center, Regensburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Epidemiology and Preventive Medicine, Regensburg University Medical Center, Regensburg</wicri:regionArea>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hiraki, Linda T" sort="Hiraki, Linda T" uniqKey="Hiraki L" first="Linda T." last="Hiraki">Linda T. Hiraki</name>
<affiliation wicri:level="1"><nlm:aff id="aff19">Genetics and Genome Biology Program, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Genetics and Genome Biology Program, The Hospital for Sick Children Research Institute, Toronto, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tayo, Bamidele O" sort="Tayo, Bamidele O" uniqKey="Tayo B" first="Bamidele O." last="Tayo">Bamidele O. Tayo</name>
<affiliation wicri:level="2"><nlm:aff id="aff20">Loyola University Chicago, Maywood, IL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Illinois</region>
</placeName>
<wicri:cityArea>Loyola University Chicago, Maywood</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Fuchsberger, Christian" sort="Fuchsberger, Christian" uniqKey="Fuchsberger C" first="Christian" last="Fuchsberger">Christian Fuchsberger</name>
<affiliation wicri:level="1"><nlm:aff id="aff13">Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano</wicri:regionArea>
<wicri:noRegion>Bolzano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dieffenbach, Aida Karina" sort="Dieffenbach, Aida Karina" uniqKey="Dieffenbach A" first="Aida Karina" last="Dieffenbach">Aida Karina Dieffenbach</name>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff22">German Cancer Consortium (DKTK), Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Cancer Consortium (DKTK), Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R." last="Shuldiner">Alan R. Shuldiner</name>
<affiliation wicri:level="2"><nlm:aff id="aff23">Department of Medicine, University of Maryland School of Medicine, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Medicine, University of Maryland School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V." last="Smith">Albert V. Smith</name>
<affiliation wicri:level="1"><nlm:aff id="aff24">Icelandic Heart Association, Kópavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kópavogur</wicri:regionArea>
<wicri:noRegion>Kópavogur</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25">Faculty of Medicine, University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea>
<wicri:noRegion>Reykjavik</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zappa, Allison M" sort="Zappa, Allison M" uniqKey="Zappa A" first="Allison M." last="Zappa">Allison M. Zappa</name>
<affiliation wicri:level="2"><nlm:aff id="aff26">Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Lupo, Antonio" sort="Lupo, Antonio" uniqKey="Lupo A" first="Antonio" last="Lupo">Antonio Lupo</name>
<affiliation wicri:level="1"><nlm:aff id="aff27">Renal Unit, Department of Medicine, University of Verona, Verona, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Renal Unit, Department of Medicine, University of Verona, Verona</wicri:regionArea>
<wicri:noRegion>Verona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kollerits, Barbara" sort="Kollerits, Barbara" uniqKey="Kollerits B" first="Barbara" last="Kollerits">Barbara Kollerits</name>
<affiliation wicri:level="4"><nlm:aff id="aff28">Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck</wicri:regionArea>
<orgName type="university">Université de médecine d'Innsbruck</orgName>
<placeName><settlement type="city">Innsbruck</settlement>
<region nuts="2" type="region">Tyrol (Land)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ponte, Belen" sort="Ponte, Belen" uniqKey="Ponte B" first="Belen" last="Ponte">Belen Ponte</name>
<affiliation wicri:level="1"><nlm:aff id="aff29">Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospitals, Geneva, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Nephrology Division, Department of Specialties of Internal Medicine, Geneva University Hospitals, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stengel, Benedicte" sort="Stengel, Benedicte" uniqKey="Stengel B" first="Bénédicte" last="Stengel">Bénédicte Stengel</name>
<affiliation wicri:level="1"><nlm:aff id="aff30">INSERM U-1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U-1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Villejuif</wicri:regionArea>
<wicri:noRegion>Villejuif</wicri:noRegion>
<wicri:noRegion>Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31">UMRS 1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Univ Paris Sud, Univ Versailles, St. Quentin, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>UMRS 1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Univ Paris Sud, Univ Versailles, St. Quentin</wicri:regionArea>
<wicri:noRegion>St. Quentin</wicri:noRegion>
<wicri:noRegion>St. Quentin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kr Mer, Bernhard K" sort="Kr Mer, Bernhard K" uniqKey="Kr Mer B" first="Bernhard K." last="Kr Mer">Bernhard K. Kr Mer</name>
<affiliation wicri:level="3"><nlm:aff id="aff32">Fifth Department of Medicine, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Fifth Department of Medicine, University Medical Centre Mannheim, University of Heidelberg, Mannheim</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Mannheim</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Paulweber, Bernhard" sort="Paulweber, Bernhard" uniqKey="Paulweber B" first="Bernhard" last="Paulweber">Bernhard Paulweber</name>
<affiliation wicri:level="1"><nlm:aff id="aff33">First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Salzburg, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Salzburg</wicri:regionArea>
<wicri:noRegion>Salzburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mitchell, Braxton D" sort="Mitchell, Braxton D" uniqKey="Mitchell B" first="Braxton D." last="Mitchell">Braxton D. Mitchell</name>
<affiliation wicri:level="2"><nlm:aff id="aff23">Department of Medicine, University of Maryland School of Medicine, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Medicine, University of Maryland School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name>
<affiliation wicri:level="4"><nlm:aff id="aff34">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland</wicri:regionArea>
<orgName type="university">Université d'Édimbourg</orgName>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Helmer, Catherine" sort="Helmer, Catherine" uniqKey="Helmer C" first="Catherine" last="Helmer">Catherine Helmer</name>
<affiliation wicri:level="3"><nlm:aff id="aff35">INSERM U897, Bordeaux University, Institut de Santé Publique, d'Epidémiologie et de Développement (ISPED), Bordeaux, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U897, Bordeaux University, Institut de Santé Publique, d'Epidémiologie et de Développement (ISPED), Bordeaux</wicri:regionArea>
<placeName><region type="region">Nouvelle-Aquitaine</region>
<region type="old region">Aquitaine</region>
<settlement type="city">Bordeaux</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Meisinger, Christa" sort="Meisinger, Christa" uniqKey="Meisinger C" first="Christa" last="Meisinger">Christa Meisinger</name>
<affiliation wicri:level="1"><nlm:aff id="aff36">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name>
<affiliation wicri:level="1"><nlm:aff id="aff37">Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shaffer, Christian M" sort="Shaffer, Christian M" uniqKey="Shaffer C" first="Christian M." last="Shaffer">Christian M. Shaffer</name>
<affiliation wicri:level="2"><nlm:aff id="aff38">Vanderbilt University School of Medicine, Nashville, TN</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Vanderbilt University School of Medicine, Nashville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Muller, Christian" sort="Muller, Christian" uniqKey="Muller C" first="Christian" last="Müller">Christian Müller</name>
<affiliation wicri:level="3"><nlm:aff id="aff39">University Heart Center Hamburg, Hamburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>University Heart Center Hamburg, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff40">German Center for Cardiovascular Research (DZHK e.V.), partner site Hamburg, Lübeck, Kiel, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK e.V.), partner site Hamburg, Lübeck, Kiel</wicri:regionArea>
<placeName><region type="land" nuts="2">Schleswig-Holstein</region>
<settlement type="city">Kiel</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff41">Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ackermann, Daniel" sort="Ackermann, Daniel" uniqKey="Ackermann D" first="Daniel" last="Ackermann">Daniel Ackermann</name>
<affiliation wicri:level="3"><nlm:aff id="aff42">University Clinic for Nephrology, Hypertension and Clinical Pharmacology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>University Clinic for Nephrology, Hypertension and Clinical Pharmacology, Inselspital, Bern University Hospital and University of Bern, Bern</wicri:regionArea>
<placeName><settlement type="city">Berne</settlement>
<region type="région" nuts="3">Canton de Berne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Siscovick, David" sort="Siscovick, David" uniqKey="Siscovick D" first="David" last="Siscovick">David Siscovick</name>
<affiliation wicri:level="2"><nlm:aff id="aff43">Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, Seattle</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name>
<affiliation wicri:level="2"><nlm:aff id="aff45">Human Genetics Center, University of Texas Health Science Center, Houston, TX</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Texas</region>
</placeName>
<wicri:cityArea>Human Genetics Center, University of Texas Health Science Center, Houston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Kronenberg, Florian" sort="Kronenberg, Florian" uniqKey="Kronenberg F" first="Florian" last="Kronenberg">Florian Kronenberg</name>
<affiliation wicri:level="4"><nlm:aff id="aff28">Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck</wicri:regionArea>
<orgName type="university">Université de médecine d'Innsbruck</orgName>
<placeName><settlement type="city">Innsbruck</settlement>
<region nuts="2" type="region">Tyrol (Land)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ehret, Georg B" sort="Ehret, Georg B" uniqKey="Ehret G" first="Georg B." last="Ehret">Georg B. Ehret</name>
<affiliation wicri:level="1"><nlm:aff id="aff46">Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospitals, Geneva, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospitals, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name>
<affiliation wicri:level="1"><nlm:aff id="aff47">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Waeber, Gerard" sort="Waeber, Gerard" uniqKey="Waeber G" first="Gerard" last="Waeber">Gerard Waeber</name>
<affiliation wicri:level="3"><nlm:aff id="aff48">Department of Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Internal Medicine, Lausanne University Hospital, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Navis, Gerjan" sort="Navis, Gerjan" uniqKey="Navis G" first="Gerjan" last="Navis">Gerjan Navis</name>
<affiliation wicri:level="3"><nlm:aff id="aff49">Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gambaro, Giovanni" sort="Gambaro, Giovanni" uniqKey="Gambaro G" first="Giovanni" last="Gambaro">Giovanni Gambaro</name>
<affiliation wicri:level="3"><nlm:aff id="aff50">Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus-Gemelli University Hospital, Catholic University, Rome, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus-Gemelli University Hospital, Catholic University, Rome</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Malerba, Giovanni" sort="Malerba, Giovanni" uniqKey="Malerba G" first="Giovanni" last="Malerba">Giovanni Malerba</name>
<affiliation wicri:level="1"><nlm:aff id="aff11">Department of Life and Reproduction Sciences, University of Verona, Verona, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Life and Reproduction Sciences, University of Verona, Verona</wicri:regionArea>
<wicri:noRegion>Verona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name>
<affiliation wicri:level="1"><nlm:aff id="aff24">Icelandic Heart Association, Kópavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kópavogur</wicri:regionArea>
<wicri:noRegion>Kópavogur</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Li, Guo" sort="Li, Guo" uniqKey="Li G" first="Guo" last="Li">Guo Li</name>
<affiliation wicri:level="2"><nlm:aff id="aff43">Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, Seattle</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H. Erich" last="Wichmann">H. Erich Wichmann</name>
<affiliation wicri:level="1"><nlm:aff id="aff51">Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff52">Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff53">Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name>
<affiliation wicri:level="1"><nlm:aff id="aff36">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff54">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff55">German Center for Diabetes Research (DZD), Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Diabetes Research (DZD), Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wallaschofski, Henri" sort="Wallaschofski, Henri" uniqKey="Wallaschofski H" first="Henri" last="Wallaschofski">Henri Wallaschofski</name>
<affiliation wicri:level="1"><nlm:aff id="aff56">Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2">German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Brenner, Herrmann" sort="Brenner, Herrmann" uniqKey="Brenner H" first="Herrmann" last="Brenner">Herrmann Brenner</name>
<affiliation wicri:level="3"><nlm:aff id="aff21">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kramer, Holly" sort="Kramer, Holly" uniqKey="Kramer H" first="Holly" last="Kramer">Holly Kramer</name>
<affiliation wicri:level="2"><nlm:aff id="aff20">Loyola University Chicago, Maywood, IL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Illinois</region>
</placeName>
<wicri:cityArea>Loyola University Chicago, Maywood</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Leach, I Mateo" sort="Leach, I Mateo" uniqKey="Leach I" first="I. Mateo" last="Leach">I. Mateo Leach</name>
<affiliation wicri:level="3"><nlm:aff id="aff57">Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name>
<affiliation wicri:level="4"><nlm:aff id="aff58">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland</wicri:regionArea>
<orgName type="university">Université d'Édimbourg</orgName>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hillege, Hans L" sort="Hillege, Hans L" uniqKey="Hillege H" first="Hans L." last="Hillege">Hans L. Hillege</name>
<affiliation wicri:level="3"><nlm:aff id="aff59">Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S." last="Beckmann">Jacques S. Beckmann</name>
<affiliation wicri:level="3"><nlm:aff id="aff60">Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff61">Swiss Institute of Bioinformatics, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lambert, Jean Charles" sort="Lambert, Jean Charles" uniqKey="Lambert J" first="Jean Charles" last="Lambert">Jean Charles Lambert</name>
<affiliation wicri:level="3"><nlm:aff id="aff62">INSERM UMR 1167 “Risk factors and molecular determinants of aging-related diseases,” Institut Pasteur de Lille, Lille, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>INSERM UMR 1167 “Risk factors and molecular determinants of aging-related diseases,” Institut Pasteur de Lille, Lille</wicri:regionArea>
<placeName><region type="region">Hauts-de-France</region>
<region type="old region">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Luan, Jian An" sort="Luan, Jian An" uniqKey="Luan J" first="Jian'An" last="Luan">Jian'An Luan</name>
<affiliation wicri:level="1"><nlm:aff id="aff41">Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name>
<affiliation wicri:level="1"><nlm:aff id="aff41">Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chalmers, John" sort="Chalmers, John" uniqKey="Chalmers J" first="John" last="Chalmers">John Chalmers</name>
<affiliation wicri:level="4"><nlm:aff id="aff63">The George Institute for Global Health, University of Sydney, Camperdown, New South Wales, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>The George Institute for Global Health, University of Sydney, Camperdown, New South Wales</wicri:regionArea>
<orgName type="university">Université de Sydney</orgName>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Coresh, Josef" sort="Coresh, Josef" uniqKey="Coresh J" first="Josef" last="Coresh">Josef Coresh</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff64">Welch Center for Prevention, Epidemiology and Clinical Research, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Welch Center for Prevention, Epidemiology and Clinical Research, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Denny, Joshua C" sort="Denny, Joshua C" uniqKey="Denny J" first="Joshua C." last="Denny">Joshua C. Denny</name>
<affiliation wicri:level="2"><nlm:aff id="aff65">Vanderbilt University School of Medicine, Nashville, TN</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Vanderbilt University School of Medicine, Nashville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Butterbach, Katja" sort="Butterbach, Katja" uniqKey="Butterbach K" first="Katja" last="Butterbach">Katja Butterbach</name>
<affiliation wicri:level="3"><nlm:aff id="aff21">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J." last="Launer">Lenore J. Launer</name>
<affiliation wicri:level="2"><nlm:aff id="aff66">Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name>
<affiliation wicri:level="2"><nlm:aff id="aff67">Clinical Research Branch, National Institute on Aging, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Clinical Research Branch, National Institute on Aging, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Kedenko, Lyudmyla" sort="Kedenko, Lyudmyla" uniqKey="Kedenko L" first="Lyudmyla" last="Kedenko">Lyudmyla Kedenko</name>
<affiliation wicri:level="1"><nlm:aff id="aff33">First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Salzburg, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>First Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken, Salzburg</wicri:regionArea>
<wicri:noRegion>Salzburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Haun, Margot" sort="Haun, Margot" uniqKey="Haun M" first="Margot" last="Haun">Margot Haun</name>
<affiliation wicri:level="4"><nlm:aff id="aff28">Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck</wicri:regionArea>
<orgName type="university">Université de médecine d'Innsbruck</orgName>
<placeName><settlement type="city">Innsbruck</settlement>
<region nuts="2" type="region">Tyrol (Land)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Metzger, Marie" sort="Metzger, Marie" uniqKey="Metzger M" first="Marie" last="Metzger">Marie Metzger</name>
<affiliation wicri:level="1"><nlm:aff id="aff30">INSERM U-1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U-1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Villejuif</wicri:regionArea>
<wicri:noRegion>Villejuif</wicri:noRegion>
<wicri:noRegion>Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31">UMRS 1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Univ Paris Sud, Univ Versailles, St. Quentin, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>UMRS 1018, Centre de recherche en épidémiologie et santé des populations (CESP) Team 5, Univ Paris Sud, Univ Versailles, St. Quentin</wicri:regionArea>
<wicri:noRegion>St. Quentin</wicri:noRegion>
<wicri:noRegion>St. Quentin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Woodward, Mark" sort="Woodward, Mark" uniqKey="Woodward M" first="Mark" last="Woodward">Mark Woodward</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff63">The George Institute for Global Health, University of Sydney, Camperdown, New South Wales, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>The George Institute for Global Health, University of Sydney, Camperdown, New South Wales</wicri:regionArea>
<orgName type="university">Université de Sydney</orgName>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff68">The George Institute for Global Health, Nuffield Department of Population Health, University of Oxford, Oxford, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>The George Institute for Global Health, Nuffield Department of Population Health, University of Oxford, Oxford</wicri:regionArea>
<placeName><settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author><name sortKey="Hoffman, Matthew J" sort="Hoffman, Matthew J" uniqKey="Hoffman M" first="Matthew J." last="Hoffman">Matthew J. Hoffman</name>
<affiliation wicri:level="2"><nlm:aff id="aff7">Department of Physiology, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Department of Physiology, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Nauck, Matthias" sort="Nauck, Matthias" uniqKey="Nauck M" first="Matthias" last="Nauck">Matthias Nauck</name>
<affiliation wicri:level="1"><nlm:aff id="aff2">German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff56">Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name>
<affiliation wicri:level="1"><nlm:aff id="aff36">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pruijm, Menno" sort="Pruijm, Menno" uniqKey="Pruijm M" first="Menno" last="Pruijm">Menno Pruijm</name>
<affiliation wicri:level="3"><nlm:aff id="aff69">Service of Nephrology, Lausanne University Hospital, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Service of Nephrology, Lausanne University Hospital, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bochud, Murielle" sort="Bochud, Murielle" uniqKey="Bochud M" first="Murielle" last="Bochud">Murielle Bochud</name>
<affiliation wicri:level="1"><nlm:aff id="aff70">University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Épalinges, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Épalinges</wicri:regionArea>
<wicri:noRegion>Épalinges</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rheinberger, Myriam" sort="Rheinberger, Myriam" uniqKey="Rheinberger M" first="Myriam" last="Rheinberger">Myriam Rheinberger</name>
<affiliation wicri:level="1"><nlm:aff id="aff71">Department of Nephrology, University Hospital Regensburg, Regensburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Nephrology, University Hospital Regensburg, Regensburg</wicri:regionArea>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name>
<affiliation wicri:level="3"><nlm:aff id="aff57">Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J." last="Wareham">Nicholas J. Wareham</name>
<affiliation wicri:level="1"><nlm:aff id="aff41">Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Endlich, Nicole" sort="Endlich, Nicole" uniqKey="Endlich N" first="Nicole" last="Endlich">Nicole Endlich</name>
<affiliation wicri:level="1"><nlm:aff id="aff72">Institute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Soranzo, Nicole" sort="Soranzo, Nicole" uniqKey="Soranzo N" first="Nicole" last="Soranzo">Nicole Soranzo</name>
<affiliation wicri:level="1"><nlm:aff id="aff73">Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Human Genetics, Wellcome Trust Sanger Institute, Hinxton</wicri:regionArea>
<wicri:noRegion>Hinxton</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff74">Department of Haematology, University of Cambridge, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Haematology, University of Cambridge, Cambridge</wicri:regionArea>
<orgName type="university">Université de Cambridge</orgName>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name>
<affiliation wicri:level="1"><nlm:aff id="aff75">Croatian Centre for Global Health, Faculty of Medicine, University of Split, Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Croatian Centre for Global Health, Faculty of Medicine, University of Split, Split</wicri:regionArea>
<wicri:noRegion>Split</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name>
<affiliation wicri:level="3"><nlm:aff id="aff59">Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pramstaller, Peter Paul" sort="Pramstaller, Peter Paul" uniqKey="Pramstaller P" first="Peter Paul" last="Pramstaller">Peter Paul Pramstaller</name>
<affiliation wicri:level="1"><nlm:aff id="aff13">Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano</wicri:regionArea>
<wicri:noRegion>Bolzano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name>
<affiliation wicri:level="3"><nlm:aff id="aff48">Department of Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Internal Medicine, Lausanne University Hospital, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wild, Philipp S" sort="Wild, Philipp S" uniqKey="Wild P" first="Philipp S." last="Wild">Philipp S. Wild</name>
<affiliation wicri:level="3"><nlm:aff id="aff76">Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg, University Mainz, Mainz</wicri:regionArea>
<placeName><region type="land" nuts="2">Rhénanie-Palatinat</region>
<settlement type="city">Mayence</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff77">Preventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Preventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz</wicri:regionArea>
<placeName><region type="land" nuts="2">Rhénanie-Palatinat</region>
<settlement type="city">Mayence</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff78">German Center for Cardiovascular Research (DZHK), Mainz, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK), Mainz</wicri:regionArea>
<placeName><region type="land" nuts="2">Rhénanie-Palatinat</region>
<settlement type="city">Mayence</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gansevoort, Ron T" sort="Gansevoort, Ron T" uniqKey="Gansevoort R" first="Ron T." last="Gansevoort">Ron T. Gansevoort</name>
<affiliation wicri:level="3"><nlm:aff id="aff59">Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
<placeName><settlement type="city">Groningue</settlement>
<region nuts="2" type="province">Groningue (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rettig, Rainer" sort="Rettig, Rainer" uniqKey="Rettig R" first="Rainer" last="Rettig">Rainer Rettig</name>
<affiliation wicri:level="1"><nlm:aff id="aff79">Institute of Physiology, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Physiology, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Biffar, Reiner" sort="Biffar, Reiner" uniqKey="Biffar R" first="Reiner" last="Biffar">Reiner Biffar</name>
<affiliation wicri:level="1"><nlm:aff id="aff80">Clinic for Prosthetic Dentistry, Gerostomatology and Material Science, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Clinic for Prosthetic Dentistry, Gerostomatology and Material Science, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Carroll, Robert J" sort="Carroll, Robert J" uniqKey="Carroll R" first="Robert J." last="Carroll">Robert J. Carroll</name>
<affiliation wicri:level="2"><nlm:aff id="aff65">Vanderbilt University School of Medicine, Nashville, TN</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Vanderbilt University School of Medicine, Nashville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Katz, Ronit" sort="Katz, Ronit" uniqKey="Katz R" first="Ronit" last="Katz">Ronit Katz</name>
<affiliation wicri:level="2"><nlm:aff id="aff81">Kidney Research Institute, Department of Medicine, University of Washington, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Kidney Research Institute, Department of Medicine, University of Washington, Seattle</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J. F." last="Loos">Ruth J. F. Loos</name>
<affiliation wicri:level="1"><nlm:aff id="aff41">Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, U.K.</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff82">Genetics of Obesity and Related Metabolic Traits Program, The Charles Bronfman Institute for Personalized Medicine, The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Genetics of Obesity and Related Metabolic Traits Program, The Charles Bronfman Institute for Personalized Medicine, The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name>
<affiliation wicri:level="2"><nlm:aff id="aff9">National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Coassin, Stefan" sort="Coassin, Stefan" uniqKey="Coassin S" first="Stefan" last="Coassin">Stefan Coassin</name>
<affiliation wicri:level="4"><nlm:aff id="aff28">Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck</wicri:regionArea>
<orgName type="university">Université de médecine d'Innsbruck</orgName>
<placeName><settlement type="city">Innsbruck</settlement>
<region nuts="2" type="region">Tyrol (Land)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bergmann, Sven" sort="Bergmann, Sven" uniqKey="Bergmann S" first="Sven" last="Bergmann">Sven Bergmann</name>
<affiliation wicri:level="3"><nlm:aff id="aff83">Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rosas, Sylvia E" sort="Rosas, Sylvia E" uniqKey="Rosas S" first="Sylvia E." last="Rosas">Sylvia E. Rosas</name>
<affiliation wicri:level="2"><nlm:aff id="aff84">Kidney and Hypertension Section, Joslin Diabetes Center and Harvard Medical School, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Kidney and Hypertension Section, Joslin Diabetes Center and Harvard Medical School, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Stracke, Sylvia" sort="Stracke, Sylvia" uniqKey="Stracke S" first="Sylvia" last="Stracke">Sylvia Stracke</name>
<affiliation wicri:level="1"><nlm:aff id="aff85">Clinic for Internal Medicine A, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Clinic for Internal Medicine A, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B." last="Harris">Tamara B. Harris</name>
<affiliation wicri:level="2"><nlm:aff id="aff66">Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Corre, Tanguy" sort="Corre, Tanguy" uniqKey="Corre T" first="Tanguy" last="Corre">Tanguy Corre</name>
<affiliation wicri:level="3"><nlm:aff id="aff83">Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zeller, Tanja" sort="Zeller, Tanja" uniqKey="Zeller T" first="Tanja" last="Zeller">Tanja Zeller</name>
<affiliation wicri:level="3"><nlm:aff id="aff39">University Heart Center Hamburg, Hamburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>University Heart Center Hamburg, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff40">German Center for Cardiovascular Research (DZHK e.V.), partner site Hamburg, Lübeck, Kiel, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK e.V.), partner site Hamburg, Lübeck, Kiel</wicri:regionArea>
<placeName><region type="land" nuts="2">Schleswig-Holstein</region>
<settlement type="city">Kiel</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name>
<affiliation wicri:level="1"><nlm:aff id="aff36">Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff86">Institute for Human Genetics, Hannover Medical School, Hannover, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute for Human Genetics, Hannover Medical School, Hannover</wicri:regionArea>
<placeName><region type="land" nuts="2">Basse-Saxe</region>
<settlement type="city">Hanovre</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff87">Hannover Unified Biobank, Hannover Medical School, Hannover, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Hannover Unified Biobank, Hannover Medical School, Hannover</wicri:regionArea>
<placeName><region type="land" nuts="2">Basse-Saxe</region>
<settlement type="city">Hanovre</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Aspelund, Thor" sort="Aspelund, Thor" uniqKey="Aspelund T" first="Thor" last="Aspelund">Thor Aspelund</name>
<affiliation wicri:level="1"><nlm:aff id="aff24">Icelandic Heart Association, Kópavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kópavogur</wicri:regionArea>
<wicri:noRegion>Kópavogur</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25">Faculty of Medicine, University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea>
<wicri:noRegion>Reykjavik</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name>
<affiliation wicri:level="2"><nlm:aff id="aff67">Clinical Research Branch, National Institute on Aging, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Clinical Research Branch, National Institute on Aging, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Lendeckel, Uwe" sort="Lendeckel, Uwe" uniqKey="Lendeckel U" first="Uwe" last="Lendeckel">Uwe Lendeckel</name>
<affiliation wicri:level="1"><nlm:aff id="aff88">Institute of Medical Biochemistry and Molecular Biology, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Medical Biochemistry and Molecular Biology, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name>
<affiliation wicri:level="1"><nlm:aff id="aff2">German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff47">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name>
<affiliation wicri:level="1"><nlm:aff id="aff24">Icelandic Heart Association, Kópavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kópavogur</wicri:regionArea>
<wicri:noRegion>Kópavogur</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25">Faculty of Medicine, University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea>
<wicri:noRegion>Reykjavik</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chouraki, Vincent" sort="Chouraki, Vincent" uniqKey="Chouraki V" first="Vincent" last="Chouraki">Vincent Chouraki</name>
<affiliation wicri:level="3"><nlm:aff id="aff62">INSERM UMR 1167 “Risk factors and molecular determinants of aging-related diseases,” Institut Pasteur de Lille, Lille, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>INSERM UMR 1167 “Risk factors and molecular determinants of aging-related diseases,” Institut Pasteur de Lille, Lille</wicri:regionArea>
<placeName><region type="region">Hauts-de-France</region>
<region type="old region">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name>
<affiliation wicri:level="3"><nlm:aff id="aff89">Abteilung Innere II, Universitätsklinikum Ulm, Ulm, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Abteilung Innere II, Universitätsklinikum Ulm, Ulm</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Ulm</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff90">Deutsches Herzzentrum München, Technische Universität München, Munich, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Deutsches Herzzentrum München, Technische Universität München, Munich</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
<settlement type="city">Munich</settlement>
</placeName>
<orgName type="university">Université technique de Munich</orgName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff91">German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kutalik, Zoltan" sort="Kutalik, Zoltan" uniqKey="Kutalik Z" first="Zoltan" last="Kutalik">Zoltan Kutalik</name>
<affiliation wicri:level="3"><nlm:aff id="aff61">Swiss Institute of Bioinformatics, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff83">Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff92">University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne</wicri:regionArea>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="O Connell, Jeffrey R" sort="O Connell, Jeffrey R" uniqKey="O Connell J" first="Jeffrey R." last="O'Connell">Jeffrey R. O'Connell</name>
<affiliation wicri:level="2"><nlm:aff id="aff23">Department of Medicine, University of Maryland School of Medicine, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Medicine, University of Maryland School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Parsa, Afshin" sort="Parsa, Afshin" uniqKey="Parsa A" first="Afshin" last="Parsa">Afshin Parsa</name>
<affiliation wicri:level="2"><nlm:aff id="aff23">Department of Medicine, University of Maryland School of Medicine, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Medicine, University of Maryland School of Medicine, Baltimore</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Heid, Iris M" sort="Heid, Iris M" uniqKey="Heid I" first="Iris M." last="Heid">Iris M. Heid</name>
<affiliation wicri:level="1"><nlm:aff id="aff5">Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg</wicri:regionArea>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff37">Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Paterson, Andrew D" sort="Paterson, Andrew D" uniqKey="Paterson A" first="Andrew D." last="Paterson">Andrew D. Paterson</name>
<affiliation wicri:level="1"><nlm:aff id="aff19">Genetics and Genome Biology Program, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Genetics and Genome Biology Program, The Hospital for Sick Children Research Institute, Toronto, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="aff93">Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="De Boer, Ian H" sort="De Boer, Ian H" uniqKey="De Boer I" first="Ian H." last="De Boer">Ian H. De Boer</name>
<affiliation wicri:level="2"><nlm:aff id="aff81">Kidney Research Institute, Department of Medicine, University of Washington, Seattle, WA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Washington (État)</region>
</placeName>
<wicri:cityArea>Kidney Research Institute, Department of Medicine, University of Washington, Seattle</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Devuyst, Olivier" sort="Devuyst, Olivier" uniqKey="Devuyst O" first="Olivier" last="Devuyst">Olivier Devuyst</name>
<affiliation wicri:level="4"><nlm:aff id="aff14">Institute of Physiology, Mechanisms of Inherited Kidney Disorders Group, University of Zürich, Zürich, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Institute of Physiology, Mechanisms of Inherited Kidney Disorders Group, University of Zürich, Zürich</wicri:regionArea>
<placeName><settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
<settlement type="city">Zurich</settlement>
</placeName>
<orgName type="university">Université de Zurich</orgName>
</affiliation>
</author>
<author><name sortKey="Lazar, Jozef" sort="Lazar, Jozef" uniqKey="Lazar J" first="Jozef" last="Lazar">Jozef Lazar</name>
<affiliation wicri:level="2"><nlm:aff id="aff94">Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Department of Dermatology, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Endlich, Karlhans" sort="Endlich, Karlhans" uniqKey="Endlich K" first="Karlhans" last="Endlich">Karlhans Endlich</name>
<affiliation wicri:level="1"><nlm:aff id="aff72">Institute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Susztak, Katalin" sort="Susztak, Katalin" uniqKey="Susztak K" first="Katalin" last="Susztak">Katalin Susztak</name>
<affiliation wicri:level="2"><nlm:aff id="aff12">Renal-Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, PA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Renal-Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Tremblay, Johanne" sort="Tremblay, Johanne" uniqKey="Tremblay J" first="Johanne" last="Tremblay">Johanne Tremblay</name>
<affiliation wicri:level="1"><nlm:aff id="aff95">Centre de Recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), University of Montreal, CHUM Research Center, Technopìle Angus, Montreal, Quebec, Canada.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Canada</country>
<wicri:regionArea>Centre de Recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), University of Montreal, CHUM Research Center, Technopìle Angus, Montreal, Quebec</wicri:regionArea>
<wicri:noRegion>Quebec</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hamet, Pavel" sort="Hamet, Pavel" uniqKey="Hamet P" first="Pavel" last="Hamet">Pavel Hamet</name>
<affiliation wicri:level="1"><nlm:aff id="aff95">Centre de Recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), University of Montreal, CHUM Research Center, Technopìle Angus, Montreal, Quebec, Canada.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Canada</country>
<wicri:regionArea>Centre de Recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), University of Montreal, CHUM Research Center, Technopìle Angus, Montreal, Quebec</wicri:regionArea>
<wicri:noRegion>Quebec</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jacob, Howard J" sort="Jacob, Howard J" uniqKey="Jacob H" first="Howard J." last="Jacob">Howard J. Jacob</name>
<affiliation wicri:level="2"><nlm:aff id="aff7">Department of Physiology, Medical College of Wisconsin, Milwaukee, WI</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Wisconsin</region>
</placeName>
<wicri:cityArea>Department of Physiology, Medical College of Wisconsin, Milwaukee</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Boger, Carsten A" sort="Boger, Carsten A" uniqKey="Boger C" first="Carsten A." last="Böger">Carsten A. Böger</name>
<affiliation wicri:level="1"><nlm:aff id="aff6">Department of Nephrology, University Hospital Regensburg, Regensburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Nephrology, University Hospital Regensburg, Regensburg</wicri:regionArea>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
<wicri:noRegion>Regensburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fox, Caroline S" sort="Fox, Caroline S" uniqKey="Fox C" first="Caroline S." last="Fox">Caroline S. Fox</name>
<affiliation wicri:level="2"><nlm:aff id="aff9">National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff96">Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Pattaro, Cristian" sort="Pattaro, Cristian" uniqKey="Pattaro C" first="Cristian" last="Pattaro">Cristian Pattaro</name>
<affiliation wicri:level="1"><nlm:aff id="aff13">Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano</wicri:regionArea>
<wicri:noRegion>Bolzano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kottgen, Anna" sort="Kottgen, Anna" uniqKey="Kottgen A" first="Anna" last="Köttgen">Anna Köttgen</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore</wicri:cityArea>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="aff10">Renal Division, Medical Center, University of Freiburg, Freiburg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Renal Division, Medical Center, University of Freiburg, Freiburg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Fribourg-en-Brisgau</region>
<settlement type="city">Fribourg-en-Brisgau</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Diabetes</title>
<idno type="ISSN">0012-1797</idno>
<idno type="eISSN">1939-327X</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Albuminuria (etiology)</term>
<term>Albuminuria (genetics)</term>
<term>Animals</term>
<term>Cathepsin C (genetics)</term>
<term>Diabetes Mellitus, Experimental</term>
<term>Diabetes Mellitus, Type 2 (complications)</term>
<term>Diabetes Mellitus, Type 2 (genetics)</term>
<term>Diabetic Nephropathies (etiology)</term>
<term>Diabetic Nephropathies (genetics)</term>
<term>Female</term>
<term>Gene Knockout Techniques</term>
<term>Genetic Predisposition to Disease</term>
<term>Genome-Wide Association Study</term>
<term>Humans</term>
<term>Kidney (metabolism)</term>
<term>Kidney Tubules (metabolism)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Polymorphism, Single Nucleotide</term>
<term>Rats</term>
<term>Receptors, Cell Surface (genetics)</term>
<term>Sulfotransferases (genetics)</term>
<term>rab GTP-Binding Proteins (genetics)</term>
<term>rab GTP-Binding Proteins (metabolism)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Albuminurie (génétique)</term>
<term>Albuminurie (étiologie)</term>
<term>Animaux</term>
<term>Cathepsine C (génétique)</term>
<term>Diabète de type 2 ()</term>
<term>Diabète de type 2 (génétique)</term>
<term>Diabète expérimental</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Néphropathies diabétiques (génétique)</term>
<term>Néphropathies diabétiques (étiologie)</term>
<term>Polymorphisme de nucléotide simple</term>
<term>Protéines G rab (génétique)</term>
<term>Protéines G rab (métabolisme)</term>
<term>Prédisposition génétique à une maladie</term>
<term>Rats</term>
<term>Rein (métabolisme)</term>
<term>Récepteurs de surface cellulaire (génétique)</term>
<term>Sujet âgé</term>
<term>Sulfotransferases (génétique)</term>
<term>Techniques de knock-out de gènes</term>
<term>Tubules rénaux (métabolisme)</term>
<term>Étude d'association pangénomique</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Cathepsin C</term>
<term>Receptors, Cell Surface</term>
<term>Sulfotransferases</term>
<term>rab GTP-Binding Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Diabetes Mellitus, Type 2</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Albuminuria</term>
<term>Diabetic Nephropathies</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Albuminuria</term>
<term>Diabetes Mellitus, Type 2</term>
<term>Diabetic Nephropathies</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Albuminurie</term>
<term>Cathepsine C</term>
<term>Diabète de type 2</term>
<term>Néphropathies diabétiques</term>
<term>Protéines G rab</term>
<term>Récepteurs de surface cellulaire</term>
<term>Sulfotransferases</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Kidney</term>
<term>Kidney Tubules</term>
<term>rab GTP-Binding Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Protéines G rab</term>
<term>Rein</term>
<term>Tubules rénaux</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Albuminurie</term>
<term>Néphropathies diabétiques</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Animals</term>
<term>Diabetes Mellitus, Experimental</term>
<term>Female</term>
<term>Gene Knockout Techniques</term>
<term>Genetic Predisposition to Disease</term>
<term>Genome-Wide Association Study</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Polymorphism, Single Nucleotide</term>
<term>Rats</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Animaux</term>
<term>Diabète de type 2</term>
<term>Diabète expérimental</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Polymorphisme de nucléotide simple</term>
<term>Prédisposition génétique à une maladie</term>
<term>Rats</term>
<term>Sujet âgé</term>
<term>Techniques de knock-out de gènes</term>
<term>Étude d'association pangénomique</term>
</keywords>
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<front><div type="abstract" xml:lang="en"><p>Elevated concentrations of albumin in the urine, albuminuria, are a hallmark of diabetic kidney disease and are associated with an increased risk for end-stage renal disease and cardiovascular events. To gain insight into the pathophysiological mechanisms underlying albuminuria, we conducted meta-analyses of genome-wide association studies and independent replication in up to 5,825 individuals of European ancestry with diabetes and up to 46,061 without diabetes, followed by functional studies. Known associations of variants in <italic>CUBN</italic>
, encoding cubilin, with the urinary albumin-to-creatinine ratio (UACR) were confirmed in the overall sample (<italic>P</italic>
= 2.4 × 10<sup>−10</sup>
). Gene-by-diabetes interactions were detected and confirmed for variants in <italic>HS6ST1</italic>
and near <italic>RAB38</italic>
/<italic>CTSC</italic>
. Single nucleotide polymorphisms at these loci demonstrated a genetic effect on UACR in individuals with but not without diabetes. The change in the average UACR per minor allele was 21% for <italic>HS6ST1</italic>
(<italic>P</italic>
= 6.3 × 10<sup>–7</sup>
) and 13% for <italic>RAB38</italic>
/<italic>CTSC</italic>
(<italic>P</italic>
= 5.8 × 10<sup>−7</sup>
). Experiments using streptozotocin-induced diabetic <italic>Rab38</italic>
knockout and control rats showed higher urinary albumin concentrations and reduced amounts of megalin and cubilin at the proximal tubule cell surface in <italic>Rab38</italic>
knockout versus control rats. Relative expression of <italic>RAB38</italic>
was higher in tubuli of patients with diabetic kidney disease compared with control subjects. The loci identified here confirm known pathways and highlight novel pathways influencing albuminuria.</p>
</div>
</front>
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</analytic>
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<biblStruct><analytic><author><name sortKey="Boger, Ca" uniqKey="Boger C">CA Böger</name>
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</author>
</analytic>
</biblStruct>
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<biblStruct><analytic><author><name sortKey="Woroniecka, Ki" uniqKey="Woroniecka K">KI Woroniecka</name>
</author>
<author><name sortKey="Park, Asd" uniqKey="Park A">ASD Park</name>
</author>
<author><name sortKey="Mohtat, D" uniqKey="Mohtat D">D Mohtat</name>
</author>
<author><name sortKey="Thomas, Db" uniqKey="Thomas D">DB Thomas</name>
</author>
<author><name sortKey="Pullman, Jm" uniqKey="Pullman J">JM Pullman</name>
</author>
<author><name sortKey="Susztak, K" uniqKey="Susztak K">K Susztak</name>
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</analytic>
</biblStruct>
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<biblStruct><analytic><author><name sortKey="Welter, D" uniqKey="Welter D">D Welter</name>
</author>
<author><name sortKey="Macarthur, J" uniqKey="Macarthur J">J MacArthur</name>
</author>
<author><name sortKey="Morales, J" uniqKey="Morales J">J Morales</name>
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<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Autriche</li>
<li>Canada</li>
<li>Croatie</li>
<li>France</li>
<li>Islande</li>
<li>Italie</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>Suisse</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Angleterre de l'Est</li>
<li>Aquitaine</li>
<li>Bade-Wurtemberg</li>
<li>Basse-Saxe</li>
<li>Bavière</li>
<li>Canton de Berne</li>
<li>Canton de Vaud</li>
<li>Canton de Zurich</li>
<li>District de Fribourg-en-Brisgau</li>
<li>District de Haute-Bavière</li>
<li>District de Karlsruhe</li>
<li>District de Tübingen</li>
<li>Groningue (province)</li>
<li>Hambourg</li>
<li>Hauts-de-France</li>
<li>Illinois</li>
<li>Latium</li>
<li>Maryland</li>
<li>Massachusetts</li>
<li>Nord-Pas-de-Calais</li>
<li>Nouvelle-Aquitaine</li>
<li>Nouvelle-Galles du Sud</li>
<li>Ontario</li>
<li>Oxfordshire</li>
<li>Pennsylvanie</li>
<li>Rhénanie-Palatinat</li>
<li>Schleswig-Holstein</li>
<li>Tennessee</li>
<li>Texas</li>
<li>Tyrol (Land)</li>
<li>Washington (État)</li>
<li>Wisconsin</li>
<li>Écosse</li>
<li>État de New York</li>
</region>
<settlement><li>Berne</li>
<li>Bordeaux</li>
<li>Cambridge</li>
<li>Fribourg-en-Brisgau</li>
<li>Groningue</li>
<li>Hambourg</li>
<li>Hanovre</li>
<li>Heidelberg</li>
<li>Innsbruck</li>
<li>Kiel</li>
<li>Lausanne</li>
<li>Lille</li>
<li>Mannheim</li>
<li>Mayence</li>
<li>Munich</li>
<li>Oxford</li>
<li>Rome</li>
<li>Sydney</li>
<li>Toronto</li>
<li>Ulm</li>
<li>Zurich</li>
<li>Édimbourg</li>
</settlement>
<orgName><li>Université d'Oxford</li>
<li>Université d'Édimbourg</li>
<li>Université de Cambridge</li>
<li>Université de Sydney</li>
<li>Université de Toronto</li>
<li>Université de Zurich</li>
<li>Université de médecine d'Innsbruck</li>
<li>Université technique de Munich</li>
</orgName>
</list>
<tree><country name="Allemagne"><noRegion><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name>
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<name sortKey="Boger, Carsten A" sort="Boger, Carsten A" uniqKey="Boger C" first="Carsten A." last="Böger">Carsten A. Böger</name>
<name sortKey="Brenner, Herrmann" sort="Brenner, Herrmann" uniqKey="Brenner H" first="Herrmann" last="Brenner">Herrmann Brenner</name>
<name sortKey="Butterbach, Katja" sort="Butterbach, Katja" uniqKey="Butterbach K" first="Katja" last="Butterbach">Katja Butterbach</name>
<name sortKey="Dieffenbach, Aida Karina" sort="Dieffenbach, Aida Karina" uniqKey="Dieffenbach A" first="Aida Karina" last="Dieffenbach">Aida Karina Dieffenbach</name>
<name sortKey="Dieffenbach, Aida Karina" sort="Dieffenbach, Aida Karina" uniqKey="Dieffenbach A" first="Aida Karina" last="Dieffenbach">Aida Karina Dieffenbach</name>
<name sortKey="Endlich, Karlhans" sort="Endlich, Karlhans" uniqKey="Endlich K" first="Karlhans" last="Endlich">Karlhans Endlich</name>
<name sortKey="Endlich, Nicole" sort="Endlich, Nicole" uniqKey="Endlich N" first="Nicole" last="Endlich">Nicole Endlich</name>
<name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name>
<name sortKey="Gorski, Mathias" sort="Gorski, Mathias" uniqKey="Gorski M" first="Mathias" last="Gorski">Mathias Gorski</name>
<name sortKey="Gorski, Mathias" sort="Gorski, Mathias" uniqKey="Gorski M" first="Mathias" last="Gorski">Mathias Gorski</name>
<name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name>
<name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name>
<name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name>
<name sortKey="Heid, Iris M" sort="Heid, Iris M" uniqKey="Heid I" first="Iris M." last="Heid">Iris M. Heid</name>
<name sortKey="Heid, Iris M" sort="Heid, Iris M" uniqKey="Heid I" first="Iris M." last="Heid">Iris M. Heid</name>
<name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name>
<name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name>
<name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name>
<name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name>
<name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name>
<name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name>
<name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name>
<name sortKey="Kottgen, Anna" sort="Kottgen, Anna" uniqKey="Kottgen A" first="Anna" last="Köttgen">Anna Köttgen</name>
<name sortKey="Kr Mer, Bernhard K" sort="Kr Mer, Bernhard K" uniqKey="Kr Mer B" first="Bernhard K." last="Kr Mer">Bernhard K. Kr Mer</name>
<name sortKey="Lendeckel, Uwe" sort="Lendeckel, Uwe" uniqKey="Lendeckel U" first="Uwe" last="Lendeckel">Uwe Lendeckel</name>
<name sortKey="Li, Yong" sort="Li, Yong" uniqKey="Li Y" first="Yong" last="Li">Yong Li</name>
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<name sortKey="Muller, Christian" sort="Muller, Christian" uniqKey="Muller C" first="Christian" last="Müller">Christian Müller</name>
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<name sortKey="Nauck, Matthias" sort="Nauck, Matthias" uniqKey="Nauck M" first="Matthias" last="Nauck">Matthias Nauck</name>
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<name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name>
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<name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name>
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<name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H. Erich" last="Wichmann">H. Erich Wichmann</name>
<name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H. Erich" last="Wichmann">H. Erich Wichmann</name>
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<name sortKey="Wild, Philipp S" sort="Wild, Philipp S" uniqKey="Wild P" first="Philipp S." last="Wild">Philipp S. Wild</name>
<name sortKey="Wild, Philipp S" sort="Wild, Philipp S" uniqKey="Wild P" first="Philipp S." last="Wild">Philipp S. Wild</name>
<name sortKey="Zeller, Tanja" sort="Zeller, Tanja" uniqKey="Zeller T" first="Tanja" last="Zeller">Tanja Zeller</name>
<name sortKey="Zeller, Tanja" sort="Zeller, Tanja" uniqKey="Zeller T" first="Tanja" last="Zeller">Tanja Zeller</name>
</country>
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<name sortKey="Chen, Ming Huei" sort="Chen, Ming Huei" uniqKey="Chen M" first="Ming-Huei" last="Chen">Ming-Huei Chen</name>
<name sortKey="Chen, Ming Huei" sort="Chen, Ming Huei" uniqKey="Chen M" first="Ming-Huei" last="Chen">Ming-Huei Chen</name>
<name sortKey="Chu, Audrey Y" sort="Chu, Audrey Y" uniqKey="Chu A" first="Audrey Y." last="Chu">Audrey Y. Chu</name>
<name sortKey="Chu, Audrey Y" sort="Chu, Audrey Y" uniqKey="Chu A" first="Audrey Y." last="Chu">Audrey Y. Chu</name>
<name sortKey="Coresh, Josef" sort="Coresh, Josef" uniqKey="Coresh J" first="Josef" last="Coresh">Josef Coresh</name>
<name sortKey="Coresh, Josef" sort="Coresh, Josef" uniqKey="Coresh J" first="Josef" last="Coresh">Josef Coresh</name>
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<name sortKey="Fox, Caroline S" sort="Fox, Caroline S" uniqKey="Fox C" first="Caroline S." last="Fox">Caroline S. Fox</name>
<name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B." last="Harris">Tamara B. Harris</name>
<name sortKey="Hoffman, Matthew J" sort="Hoffman, Matthew J" uniqKey="Hoffman M" first="Matthew J." last="Hoffman">Matthew J. Hoffman</name>
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<name sortKey="Kottgen, Anna" sort="Kottgen, Anna" uniqKey="Kottgen A" first="Anna" last="Köttgen">Anna Köttgen</name>
<name sortKey="Kramer, Holly" sort="Kramer, Holly" uniqKey="Kramer H" first="Holly" last="Kramer">Holly Kramer</name>
<name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J." last="Launer">Lenore J. Launer</name>
<name sortKey="Lazar, Jozef" sort="Lazar, Jozef" uniqKey="Lazar J" first="Jozef" last="Lazar">Jozef Lazar</name>
<name sortKey="Li, Guo" sort="Li, Guo" uniqKey="Li G" first="Guo" last="Li">Guo Li</name>
<name sortKey="Li, Man" sort="Li, Man" uniqKey="Li M" first="Man" last="Li">Man Li</name>
<name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J. F." last="Loos">Ruth J. F. Loos</name>
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</region>
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<name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S." last="Beckmann">Jacques S. Beckmann</name>
<name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S." last="Beckmann">Jacques S. Beckmann</name>
<name sortKey="Bergmann, Sven" sort="Bergmann, Sven" uniqKey="Bergmann S" first="Sven" last="Bergmann">Sven Bergmann</name>
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<name sortKey="Kutalik, Zoltan" sort="Kutalik, Zoltan" uniqKey="Kutalik Z" first="Zoltan" last="Kutalik">Zoltan Kutalik</name>
<name sortKey="Kutalik, Zoltan" sort="Kutalik, Zoltan" uniqKey="Kutalik Z" first="Zoltan" last="Kutalik">Zoltan Kutalik</name>
<name sortKey="Kutalik, Zoltan" sort="Kutalik, Zoltan" uniqKey="Kutalik Z" first="Zoltan" last="Kutalik">Zoltan Kutalik</name>
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<country name="Canada"><noRegion><name sortKey="Hiraki, Linda T" sort="Hiraki, Linda T" uniqKey="Hiraki L" first="Linda T." last="Hiraki">Linda T. Hiraki</name>
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<name sortKey="Paterson, Andrew D" sort="Paterson, Andrew D" uniqKey="Paterson A" first="Andrew D." last="Paterson">Andrew D. Paterson</name>
<name sortKey="Tremblay, Johanne" sort="Tremblay, Johanne" uniqKey="Tremblay J" first="Johanne" last="Tremblay">Johanne Tremblay</name>
</country>
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<name sortKey="Aspelund, Thor" sort="Aspelund, Thor" uniqKey="Aspelund T" first="Thor" last="Aspelund">Thor Aspelund</name>
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<name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name>
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</country>
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<country name="France"><noRegion><name sortKey="Stengel, Benedicte" sort="Stengel, Benedicte" uniqKey="Stengel B" first="Bénédicte" last="Stengel">Bénédicte Stengel</name>
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<name sortKey="Metzger, Marie" sort="Metzger, Marie" uniqKey="Metzger M" first="Marie" last="Metzger">Marie Metzger</name>
<name sortKey="Stengel, Benedicte" sort="Stengel, Benedicte" uniqKey="Stengel B" first="Bénédicte" last="Stengel">Bénédicte Stengel</name>
</country>
<country name="Royaume-Uni"><region name="Écosse"><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name>
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<name sortKey="Soranzo, Nicole" sort="Soranzo, Nicole" uniqKey="Soranzo N" first="Nicole" last="Soranzo">Nicole Soranzo</name>
<name sortKey="Soranzo, Nicole" sort="Soranzo, Nicole" uniqKey="Soranzo N" first="Nicole" last="Soranzo">Nicole Soranzo</name>
<name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J." last="Wareham">Nicholas J. Wareham</name>
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<name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name>
</country>
<country name="Pays-Bas"><region name="Groningue (province)"><name sortKey="Navis, Gerjan" sort="Navis, Gerjan" uniqKey="Navis G" first="Gerjan" last="Navis">Gerjan Navis</name>
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<name sortKey="Gansevoort, Ron T" sort="Gansevoort, Ron T" uniqKey="Gansevoort R" first="Ron T." last="Gansevoort">Ron T. Gansevoort</name>
<name sortKey="Hillege, Hans L" sort="Hillege, Hans L" uniqKey="Hillege H" first="Hans L." last="Hillege">Hans L. Hillege</name>
<name sortKey="Leach, I Mateo" sort="Leach, I Mateo" uniqKey="Leach I" first="I. Mateo" last="Leach">I. Mateo Leach</name>
<name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name>
<name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name>
</country>
<country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Chalmers, John" sort="Chalmers, John" uniqKey="Chalmers J" first="John" last="Chalmers">John Chalmers</name>
</region>
<name sortKey="Woodward, Mark" sort="Woodward, Mark" uniqKey="Woodward M" first="Mark" last="Woodward">Mark Woodward</name>
</country>
<country name="Croatie"><noRegion><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name>
</noRegion>
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</tree>
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</record>
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