Knowledge engineering for health: A new discipline required to bridge the “ICT gap” between research and healthcare
Identifieur interne : 000635 ( Istex/Curation ); précédent : 000634; suivant : 000636Knowledge engineering for health: A new discipline required to bridge the “ICT gap” between research and healthcare
Auteurs : Tim Beck [Royaume-Uni] ; Sirisha Gollapudi [Royaume-Uni] ; S Ren Brunak [Danemark] ; Norbert Graf [Allemagne] ; Heinz U. Lemke [Allemagne] ; Debasis Dash [Inde] ; Iain Buchan [Royaume-Uni] ; Carlos Díaz [Espagne] ; Ferran Sanz [Espagne] ; Anthony J. Brookes [Royaume-Uni]Source :
- Human Mutation [ 1059-7794 ] ; 2012-05.
English descriptors
- KwdEn :
- Teeft :
- Biomedical informatics, Biomedical research, Clinical medicine, Computer modeling, Decision support, Ehrs, Free text, Future healthcare, Gen2phen project, Healthcare, Healthcare informatics, Healthcare providers, Human mutation, I4health, I4health concept, Informatics, Interdisciplinary experts, Knowledge engineering, Knowledge transmission, Latest research knowledge, Modeling, More facts, Patient data, Population level, Relevant advances, Research community, Research data, Research world, Treatment response, Wiley periodicals, Workshop delegates.
Abstract
Despite vast amount of money and research being channeled toward biomedical research, relatively little impact has been made on routine clinical practice. At the heart of this failure is the information and communication technology “chasm” that exists between research and healthcare. A new focus on “knowledge engineering for health” is needed to facilitate knowledge transmission across the research–healthcare gap. This discipline is required to engineer the bidirectional flow of data: processing research data and knowledge to identify clinically relevant advances and delivering these into healthcare use; conversely, making outcomes from the practice of medicine suitably available for use by the research community. This system will be able to self‐optimize in that outcomes for patients treated by decisions that were based on the latest research knowledge will be fed back to the research world. A series of meetings, culminating in the “I‐Health 2011” workshop, have brought together interdisciplinary experts to map the challenges and requirements for such a system. Here, we describe the main conclusions from these meetings. An “I4Health” interdisciplinary network of experts now exists to promote the key aims and objectives, namely “integrating and interpreting information for individualized healthcare,” by developing the “knowledge engineering for health” domain. Hum Mutat 33:797–802, 2012. © 2012 Wiley Periodicals, Inc.
Url:
DOI: 10.1002/humu.22066
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000667
Links to Exploration step
ISTEX:3FD2846672BF3417AFDCE85F1A73A33521BFE299Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Knowledge engineering for health: A new discipline required to bridge the “ICT gap” between research and healthcare</title><author><name sortKey="Beck, Tim" sort="Beck, Tim" uniqKey="Beck T" first="Tim" last="Beck">Tim Beck</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, University of Leicester, Leicester, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea></affiliation></author><author><name sortKey="Gollapudi, Sirisha" sort="Gollapudi, Sirisha" uniqKey="Gollapudi S" first="Sirisha" last="Gollapudi">Sirisha Gollapudi</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, University of Leicester, Leicester, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea></affiliation></author><author><name sortKey="Brunak, S Ren" sort="Brunak, S Ren" uniqKey="Brunak S" first="S Ren" last="Brunak">S Ren Brunak</name><affiliation wicri:level="1"><mods:affiliation>Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Disease Systems Biology, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Disease Systems Biology, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Graf, Norbert" sort="Graf, Norbert" uniqKey="Graf N" first="Norbert" last="Graf">Norbert Graf</name><affiliation wicri:level="1"><mods:affiliation>Department of Pediatric Oncology, University of Saarland Medical School, Homburg, Saar, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pediatric Oncology, University of Saarland Medical School, Homburg, Saar</wicri:regionArea></affiliation></author><author><name sortKey="Lemke, Heinz U" sort="Lemke, Heinz U" uniqKey="Lemke H" first="Heinz U." last="Lemke">Heinz U. Lemke</name><affiliation wicri:level="1"><mods:affiliation>International Foundation for Computer‐Assisted Radiology and Surgery, Kuessaberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>International Foundation for Computer‐Assisted Radiology and Surgery, Kuessaberg</wicri:regionArea></affiliation></author><author><name sortKey="Dash, Debasis" sort="Dash, Debasis" uniqKey="Dash D" first="Debasis" last="Dash">Debasis Dash</name><affiliation wicri:level="1"><mods:affiliation>GNR Knowledge Center for Genome Informatics, Institute of Genomics and Integrative Biology, Council of Scientific and Industrial Research, Delhi, India</mods:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>GNR Knowledge Center for Genome Informatics, Institute of Genomics and Integrative Biology, Council of Scientific and Industrial Research, Delhi</wicri:regionArea></affiliation></author><author><name sortKey="Buchan, Iain" sort="Buchan, Iain" uniqKey="Buchan I" first="Iain" last="Buchan">Iain Buchan</name><affiliation wicri:level="1"><mods:affiliation>North West Institute for BioHealth Informatics, University of Manchester, Manchester, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>North West Institute for BioHealth Informatics, University of Manchester, Manchester</wicri:regionArea></affiliation></author><author><name sortKey="Diaz, Carlos" sort="Diaz, Carlos" uniqKey="Diaz C" first="Carlos" last="Díaz">Carlos Díaz</name><affiliation wicri:level="1"><mods:affiliation>European Projects Management and Coordination Office, Fundació IMIM, Barcelona, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>European Projects Management and Coordination Office, Fundació IMIM, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Sanz, Ferran" sort="Sanz, Ferran" uniqKey="Sanz F" first="Ferran" last="Sanz">Ferran Sanz</name><affiliation wicri:level="1"><mods:affiliation>Research Programme on Biomedical Informatics, IMIM‐Hospital del Mar, Pompeu Fabra University, Barcelona, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Research Programme on Biomedical Informatics, IMIM‐Hospital del Mar, Pompeu Fabra University, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Brookes, Anthony J" sort="Brookes, Anthony J" uniqKey="Brookes A" first="Anthony J." last="Brookes">Anthony J. Brookes</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, University of Leicester, Leicester, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:3FD2846672BF3417AFDCE85F1A73A33521BFE299</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1002/humu.22066</idno><idno type="url">https://api.istex.fr/document/3FD2846672BF3417AFDCE85F1A73A33521BFE299/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000667</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000667</idno><idno type="wicri:Area/Istex/Curation">000635</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Knowledge engineering for health: A new discipline required to bridge the “ICT gap” between research and healthcare</title><author><name sortKey="Beck, Tim" sort="Beck, Tim" uniqKey="Beck T" first="Tim" last="Beck">Tim Beck</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, University of Leicester, Leicester, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea></affiliation></author><author><name sortKey="Gollapudi, Sirisha" sort="Gollapudi, Sirisha" uniqKey="Gollapudi S" first="Sirisha" last="Gollapudi">Sirisha Gollapudi</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, University of Leicester, Leicester, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea></affiliation></author><author><name sortKey="Brunak, S Ren" sort="Brunak, S Ren" uniqKey="Brunak S" first="S Ren" last="Brunak">S Ren Brunak</name><affiliation wicri:level="1"><mods:affiliation>Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Disease Systems Biology, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Disease Systems Biology, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Graf, Norbert" sort="Graf, Norbert" uniqKey="Graf N" first="Norbert" last="Graf">Norbert Graf</name><affiliation wicri:level="1"><mods:affiliation>Department of Pediatric Oncology, University of Saarland Medical School, Homburg, Saar, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pediatric Oncology, University of Saarland Medical School, Homburg, Saar</wicri:regionArea></affiliation></author><author><name sortKey="Lemke, Heinz U" sort="Lemke, Heinz U" uniqKey="Lemke H" first="Heinz U." last="Lemke">Heinz U. Lemke</name><affiliation wicri:level="1"><mods:affiliation>International Foundation for Computer‐Assisted Radiology and Surgery, Kuessaberg, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>International Foundation for Computer‐Assisted Radiology and Surgery, Kuessaberg</wicri:regionArea></affiliation></author><author><name sortKey="Dash, Debasis" sort="Dash, Debasis" uniqKey="Dash D" first="Debasis" last="Dash">Debasis Dash</name><affiliation wicri:level="1"><mods:affiliation>GNR Knowledge Center for Genome Informatics, Institute of Genomics and Integrative Biology, Council of Scientific and Industrial Research, Delhi, India</mods:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>GNR Knowledge Center for Genome Informatics, Institute of Genomics and Integrative Biology, Council of Scientific and Industrial Research, Delhi</wicri:regionArea></affiliation></author><author><name sortKey="Buchan, Iain" sort="Buchan, Iain" uniqKey="Buchan I" first="Iain" last="Buchan">Iain Buchan</name><affiliation wicri:level="1"><mods:affiliation>North West Institute for BioHealth Informatics, University of Manchester, Manchester, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>North West Institute for BioHealth Informatics, University of Manchester, Manchester</wicri:regionArea></affiliation></author><author><name sortKey="Diaz, Carlos" sort="Diaz, Carlos" uniqKey="Diaz C" first="Carlos" last="Díaz">Carlos Díaz</name><affiliation wicri:level="1"><mods:affiliation>European Projects Management and Coordination Office, Fundació IMIM, Barcelona, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>European Projects Management and Coordination Office, Fundació IMIM, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Sanz, Ferran" sort="Sanz, Ferran" uniqKey="Sanz F" first="Ferran" last="Sanz">Ferran Sanz</name><affiliation wicri:level="1"><mods:affiliation>Research Programme on Biomedical Informatics, IMIM‐Hospital del Mar, Pompeu Fabra University, Barcelona, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Research Programme on Biomedical Informatics, IMIM‐Hospital del Mar, Pompeu Fabra University, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Brookes, Anthony J" sort="Brookes, Anthony J" uniqKey="Brookes A" first="Anthony J." last="Brookes">Anthony J. Brookes</name><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, University of Leicester, Leicester, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, United Kingdom</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Human Mutation</title><title level="j" type="abbrev">Hum. Mutat.</title><idno type="ISSN">1059-7794</idno><idno type="eISSN">1098-1004</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2012-05">2012-05</date><biblScope unit="volume">33</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="797">797</biblScope><biblScope unit="page" to="802">802</biblScope></imprint><idno type="ISSN">1059-7794</idno></series><idno type="istex">3FD2846672BF3417AFDCE85F1A73A33521BFE299</idno><idno type="DOI">10.1002/humu.22066</idno><idno type="ArticleID">HUMU22066</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1059-7794</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>ICT</term><term>I‐Health 2011</term><term>biomedical research</term><term>healthcare</term><term>personalized medicine</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Biomedical informatics</term><term>Biomedical research</term><term>Clinical medicine</term><term>Computer modeling</term><term>Decision support</term><term>Ehrs</term><term>Free text</term><term>Future healthcare</term><term>Gen2phen project</term><term>Healthcare</term><term>Healthcare informatics</term><term>Healthcare providers</term><term>Human mutation</term><term>I4health</term><term>I4health concept</term><term>Informatics</term><term>Interdisciplinary experts</term><term>Knowledge engineering</term><term>Knowledge transmission</term><term>Latest research knowledge</term><term>Modeling</term><term>More facts</term><term>Patient data</term><term>Population level</term><term>Relevant advances</term><term>Research community</term><term>Research data</term><term>Research world</term><term>Treatment response</term><term>Wiley periodicals</term><term>Workshop delegates</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Despite vast amount of money and research being channeled toward biomedical research, relatively little impact has been made on routine clinical practice. At the heart of this failure is the information and communication technology “chasm” that exists between research and healthcare. A new focus on “knowledge engineering for health” is needed to facilitate knowledge transmission across the research–healthcare gap. This discipline is required to engineer the bidirectional flow of data: processing research data and knowledge to identify clinically relevant advances and delivering these into healthcare use; conversely, making outcomes from the practice of medicine suitably available for use by the research community. This system will be able to self‐optimize in that outcomes for patients treated by decisions that were based on the latest research knowledge will be fed back to the research world. A series of meetings, culminating in the “I‐Health 2011” workshop, have brought together interdisciplinary experts to map the challenges and requirements for such a system. Here, we describe the main conclusions from these meetings. An “I4Health” interdisciplinary network of experts now exists to promote the key aims and objectives, namely “integrating and interpreting information for individualized healthcare,” by developing the “knowledge engineering for health” domain. Hum Mutat 33:797–802, 2012. © 2012 Wiley Periodicals, Inc.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sarre/explor/MusicSarreV3/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000635 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 000635 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sarre
|area= MusicSarreV3
|flux= Istex
|étape= Curation
|type= RBID
|clé= ISTEX:3FD2846672BF3417AFDCE85F1A73A33521BFE299
|texte= Knowledge engineering for health: A new discipline required to bridge the “ICT gap” between research and healthcare
}}
| This area was generated with Dilib version V0.6.33. |  |