Preliminary evidence for Herpes labialis recurrence following experimentally induced disgust.
Identifieur interne : 000832 ( PubMed/Corpus ); précédent : 000831; suivant : 000833Preliminary evidence for Herpes labialis recurrence following experimentally induced disgust.
Auteurs : A. Buske-Kirschbaum ; A. Geiben ; C. Wermke ; K M Pirke ; D. HellhammerSource :
- Psychotherapy and psychosomatics [ 0033-3190 ]
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Hydrocortisone, Tumor Necrosis Factor-alpha.
- isolation & purification : Herpesvirus 1, Human.
- metabolism : Herpes Labialis.
- microbiology : Herpes Labialis.
- psychology : Herpes Labialis.
- Adult, Affect, Attitude to Health, Female, Humans, Male, Random Allocation, Recurrence.
Abstract
After primary orofacial infection with the herpes simplex virus (type 1, HSV-1), up to 40% of HSV seropositive subjects suffer recurrent herpes infections which are characterized by painful erosions of the involved skin mainly around the lips (herpes labialis). Besides various other factors, there is growing evidence suggesting that psychosocial factors might trigger HSV. The present study was designed to investigate modulation of recurrent HSV infection by experimentally induced emotional distress.
DOI: 56231
PubMed: 11244389
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pubmed:11244389Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Preliminary evidence for Herpes labialis recurrence following experimentally induced disgust.</title><author><name sortKey="Buske Kirschbaum, A" sort="Buske Kirschbaum, A" uniqKey="Buske Kirschbaum A" first="A" last="Buske-Kirschbaum">A. Buske-Kirschbaum</name><affiliation><nlm:affiliation>Center for Psychobiology and Psychosomatic Research, University of Trier, D-54286 Trier, Germany. Buske@uni-trier.de</nlm:affiliation></affiliation></author><author><name sortKey="Geiben, A" sort="Geiben, A" uniqKey="Geiben A" first="A" last="Geiben">A. Geiben</name></author><author><name sortKey="Wermke, C" sort="Wermke, C" uniqKey="Wermke C" first="C" last="Wermke">C. Wermke</name></author><author><name sortKey="Pirke, K M" sort="Pirke, K M" uniqKey="Pirke K" first="K M" last="Pirke">K M Pirke</name></author><author><name sortKey="Hellhammer, D" sort="Hellhammer, D" uniqKey="Hellhammer D" first="D" last="Hellhammer">D. Hellhammer</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>2001 Mar-Apr</MedlineDate></PubDate></date><idno type="RBID">pubmed:11244389</idno><idno type="pmid">11244389</idno><idno type="doi">56231</idno><idno type="wicri:Area/PubMed/Corpus">000832</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000832</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Preliminary evidence for Herpes labialis recurrence following experimentally induced disgust.</title><author><name sortKey="Buske Kirschbaum, A" sort="Buske Kirschbaum, A" uniqKey="Buske Kirschbaum A" first="A" last="Buske-Kirschbaum">A. Buske-Kirschbaum</name><affiliation><nlm:affiliation>Center for Psychobiology and Psychosomatic Research, University of Trier, D-54286 Trier, Germany. Buske@uni-trier.de</nlm:affiliation></affiliation></author><author><name sortKey="Geiben, A" sort="Geiben, A" uniqKey="Geiben A" first="A" last="Geiben">A. Geiben</name></author><author><name sortKey="Wermke, C" sort="Wermke, C" uniqKey="Wermke C" first="C" last="Wermke">C. Wermke</name></author><author><name sortKey="Pirke, K M" sort="Pirke, K M" uniqKey="Pirke K" first="K M" last="Pirke">K M Pirke</name></author><author><name sortKey="Hellhammer, D" sort="Hellhammer, D" uniqKey="Hellhammer D" first="D" last="Hellhammer">D. Hellhammer</name></author></analytic><series><title level="j">Psychotherapy and psychosomatics</title><idno type="ISSN">0033-3190</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Affect</term><term>Attitude to Health</term><term>Female</term><term>Herpes Labialis (metabolism)</term><term>Herpes Labialis (microbiology)</term><term>Herpes Labialis (psychology)</term><term>Herpesvirus 1, Human (isolation & purification)</term><term>Humans</term><term>Hydrocortisone (metabolism)</term><term>Male</term><term>Random Allocation</term><term>Recurrence</term><term>Tumor Necrosis Factor-alpha (metabolism)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Hydrocortisone</term><term>Tumor Necrosis Factor-alpha</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Herpesvirus 1, Human</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Herpes Labialis</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Herpes Labialis</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Herpes Labialis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Affect</term><term>Attitude to Health</term><term>Female</term><term>Humans</term><term>Male</term><term>Random Allocation</term><term>Recurrence</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">After primary orofacial infection with the herpes simplex virus (type 1, HSV-1), up to 40% of HSV seropositive subjects suffer recurrent herpes infections which are characterized by painful erosions of the involved skin mainly around the lips (herpes labialis). Besides various other factors, there is growing evidence suggesting that psychosocial factors might trigger HSV. The present study was designed to investigate modulation of recurrent HSV infection by experimentally induced emotional distress.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">11244389</PMID><DateCreated><Year>2001</Year><Month>03</Month><Day>13</Day></DateCreated><DateCompleted><Year>2001</Year><Month>06</Month><Day>21</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0033-3190</ISSN><JournalIssue CitedMedium="Print"><Volume>70</Volume><Issue>2</Issue><PubDate><MedlineDate>2001 Mar-Apr</MedlineDate></PubDate></JournalIssue><Title>Psychotherapy and psychosomatics</Title><ISOAbbreviation>Psychother Psychosom</ISOAbbreviation></Journal><ArticleTitle>Preliminary evidence for Herpes labialis recurrence following experimentally induced disgust.</ArticleTitle><Pagination><MedlinePgn>86-91</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">After primary orofacial infection with the herpes simplex virus (type 1, HSV-1), up to 40% of HSV seropositive subjects suffer recurrent herpes infections which are characterized by painful erosions of the involved skin mainly around the lips (herpes labialis). Besides various other factors, there is growing evidence suggesting that psychosocial factors might trigger HSV. The present study was designed to investigate modulation of recurrent HSV infection by experimentally induced emotional distress.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Among patients with herpes labialis (n = 91), subjects who showed recurrent HSV infection (>5 acute infections/year) and who reported to suffer from HSV symptoms exclusively after confrontation with dirty dishes, i.e. dirty plates or dirty glasses were selected by standardized interview. Subjects (n = 20) were randomly assigned to two treatment groups. The experimental group (n = 10) was first exposed to 5 slides showing dirty glasses and subsequently to the glasses previously presented on the slides in vivo. The control group (n = 10) was exposed to neutral slides and neutral objects. In order to determine the proportion of leukocyte subpopulations and concentrations of tumor necrosis factor alpha (TNF-alpha), blood samples were collected 15 min before as well as 40 min and 48 h after stimulus presentation. Saliva cortisol was obtained 45, 20, 15 and 1 min before and 1, 10, 20 and 30 min after stimulus confrontation.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Medical examination of the volunteers 48 h after the experiment indicated that four experimental subjects showed HSV-1 symptoms while not a single herpetic infection could be determined in the control subjects (p = 0.033). Moreover, significantly elevated concentrations of TNF-alpha were observed in the experimental, but not in the control group. No significant alterations of the number of leukocyte subpopulations were found 30 min or 48 h after stimulus presentation. Further, cortisol concentrations were found to be unchanged after the treatment.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The present findings suggest that experimentally induced emotional stress such as disgust may be associated with reactivation of HSV.</AbstractText><CopyrightInformation>Copyright 2001 S. Karger AG, Basel</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Buske-Kirschbaum</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Center for Psychobiology and Psychosomatic Research, University of Trier, D-54286 Trier, Germany. Buske@uni-trier.de</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Geiben</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Wermke</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Pirke</LastName><ForeName>K M</ForeName><Initials>KM</Initials></Author><Author ValidYN="Y"><LastName>Hellhammer</LastName><ForeName>D</ForeName><Initials>D</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016449">Randomized Controlled Trial</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Psychother Psychosom</MedlineTA><NlmUniqueID>0024046</NlmUniqueID><ISSNLinking>0033-3190</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014409">Tumor Necrosis Factor-alpha</NameOfSubstance></Chemical><Chemical><RegistryNumber>WI4X0X7BPJ</RegistryNumber><NameOfSubstance UI="D006854">Hydrocortisone</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000339" MajorTopicYN="Y">Affect</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001294" MajorTopicYN="Y">Attitude to Health</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006560" MajorTopicYN="N">Herpes Labialis</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName><QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018259" MajorTopicYN="N">Herpesvirus 1, Human</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006854" MajorTopicYN="N">Hydrocortisone</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011897" MajorTopicYN="N">Random Allocation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012008" MajorTopicYN="N">Recurrence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014409" MajorTopicYN="N">Tumor Necrosis Factor-alpha</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2001</Year><Month>3</Month><Day>13</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2001</Year><Month>6</Month><Day>22</Day><Hour>10</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2001</Year><Month>3</Month><Day>13</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">11244389</ArticleId><ArticleId IdType="pii">56231</ArticleId><ArticleId IdType="doi">56231</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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