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[Autonomic neuropathy in somatization disorders].

Identifieur interne : 000A59 ( PubMed/Checkpoint ); précédent : 000A58; suivant : 000A60

[Autonomic neuropathy in somatization disorders].

Auteurs : Kurt Laederach-Hofmann [Suisse] ; Lutz Mussgay ; Thomas Wilde ; Heinz Rüddel

Source :

RBID : pubmed:11941524

English descriptors

Abstract

We conducted a study to investigate whether patients with somatization disorder show abnormal values in autonomic testing, especially in the central baroreceptor sensitivity.

DOI: 10.1055/s-2002-24960
PubMed: 11941524


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pubmed:11941524

Le document en format XML

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<title xml:lang="en">[Autonomic neuropathy in somatization disorders].</title>
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<name sortKey="Laederach Hofmann, Kurt" sort="Laederach Hofmann, Kurt" uniqKey="Laederach Hofmann K" first="Kurt" last="Laederach-Hofmann">Kurt Laederach-Hofmann</name>
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<nlm:affiliation>Zentrum für Psychobiologie und Psychosomatik der Universität Trier, Psychosomatische Fachklinik St. Franziska-Stift, Bad Kreuznach. laederach@insel.ch</nlm:affiliation>
<country wicri:rule="url">Suisse</country>
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<name sortKey="Mussgay, Lutz" sort="Mussgay, Lutz" uniqKey="Mussgay L" first="Lutz" last="Mussgay">Lutz Mussgay</name>
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<name sortKey="Wilde, Thomas" sort="Wilde, Thomas" uniqKey="Wilde T" first="Thomas" last="Wilde">Thomas Wilde</name>
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<name sortKey="Ruddel, Heinz" sort="Ruddel, Heinz" uniqKey="Ruddel H" first="Heinz" last="Rüddel">Heinz Rüddel</name>
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<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<term>Blood Pressure</term>
<term>Pressoreceptors</term>
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<term>Autonomic Nervous System</term>
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<div type="abstract" xml:lang="en">We conducted a study to investigate whether patients with somatization disorder show abnormal values in autonomic testing, especially in the central baroreceptor sensitivity.</div>
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<AbstractText Label="AIM" NlmCategory="OBJECTIVE">We conducted a study to investigate whether patients with somatization disorder show abnormal values in autonomic testing, especially in the central baroreceptor sensitivity.</AbstractText>
<AbstractText Label="PATIENTS AND METHODS" NlmCategory="METHODS">Seventy-one patients were included. All had a diagnosis of somatization disorder (ICD-10, F45.0). Psychometric testing was performed by means of validated questionnaires (STAI, STAXI, FPI, GBB, ADS, SOMS, SCL-90-R). Autonomic regulation was analyzed by international standards using frequency spectral calculation by fast Fourier transformation. Thereby 3 different groups were detected: 12 patients with a baroreceptor sensitivity (BRS) of less than 3.0 ms/mm Hg, 20 patients with normal BRS (> 9.0 ms/mm Hg), and an in-between group (n = 39) with intermediate BRS. Controlling for age, a covariance analysis was calculated.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The two extreme groups showed no difference in psychometric testing. However, significant differences were discernible in spectral values of mid-frequency-band (p < 0.05) in a covariance analysis with age as covariate. Equally the 24 h blood pressure determination showed significantly higher values for the group with BRS < 3.0 ms/mm Hg (p < 0.05 to 0.001).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">In a high percentage (17 %) of patients diagnosed to have somatization disorder autonomic dysregulation becomes apparent and is accompanied by increased blood pressure. Therefore it doesn't seem accurate to overlook concomitant organic lesions in somatization disorders despite patients lacking overtly clinical signs but suffering from various unspecific symptoms.</AbstractText>
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