The low-dose dexamethasone suppression test in fibromyalgia.
Identifieur interne : 001277 ( Main/Exploration ); précédent : 001276; suivant : 001278The low-dose dexamethasone suppression test in fibromyalgia.
Auteurs : Katja Wingenfeld [Allemagne] ; Dieter Wagner ; Iris Schmidt ; Gunther Meinlschmidt ; Dirk H. Hellhammer ; Christine HeimSource :
- Journal of psychosomatic research [ 0022-3999 ] ; 2007.
English descriptors
- KwdEn :
- Adrenocorticotropic Hormone (blood), Adult, Anxiety (blood), Anxiety (psychology), Biofeedback, Psychology (physiology), Depression (blood), Depression (psychology), Dexamethasone (administration & dosage), Dose-Response Relationship, Drug, Fatigue (blood), Fatigue (psychology), Female, Fibromyalgia (blood), Fibromyalgia (psychology), Humans, Hydrocortisone (blood), Hypothalamo-Hypophyseal System (physiopathology), Middle Aged, Pain (blood), Pain (psychology), Pituitary-Adrenal System (physiopathology).
- MESH :
- chemical , administration & dosage : Dexamethasone.
- chemical , blood : Adrenocorticotropic Hormone, Hydrocortisone.
- blood : Anxiety, Depression, Fatigue, Fibromyalgia, Pain.
- physiology : Biofeedback, Psychology.
- physiopathology : Hypothalamo-Hypophyseal System, Pituitary-Adrenal System.
- psychology : Anxiety, Depression, Fatigue, Fibromyalgia, Pain.
- Adult, Dose-Response Relationship, Drug, Female, Humans, Middle Aged.
Abstract
Fibromyalgia syndrome (FMS) has been associated with decreased cortisol secretion. Patients with posttraumatic stress disorder (PTSD) exhibit similar hypocortisolism in the context of increased negative feedback sensitivity of the hypothalamic-pituitary-adrenal (HPA) axis. Because trauma and PTSD have been associated with fibromyalgia, we evaluated whether patients with fibromyalgia demonstrate increased HPA feedback sensitivity.
DOI: 10.1016/j.jpsychores.2006.06.006
PubMed: 17188125
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Fibromyalgia syndrome (FMS) has been associated with decreased cortisol secretion. Patients with posttraumatic stress disorder (PTSD) exhibit similar hypocortisolism in the context of increased negative feedback sensitivity of the hypothalamic-pituitary-adrenal (HPA) axis. Because trauma and PTSD have been associated with fibromyalgia, we evaluated whether patients with fibromyalgia demonstrate increased HPA feedback sensitivity.</div>
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