Psychobiological factors related to human natural killer cell activity and hormonal modulation of NK cells in vitro
Identifieur interne : 001954 ( Istex/Corpus ); précédent : 001953; suivant : 001955Psychobiological factors related to human natural killer cell activity and hormonal modulation of NK cells in vitro
Auteurs : Robert J. Benschop ; Lea Jabaaij ; Frank G. Oostveen ; Ad J. J. M. Vingerhoets ; Clemens Kirschbaum ; Hugo J. Duivenvoorden ; Rudy E. BallieuxSource :
- Life Sciences [ 0024-3205 ] ; 1993.
Abstract
The present report investigated whether percentages of circulating natural killer (NK) cells and NK cell activity (NKCA) are associated with psychological variables. Subjects (n=95) were selected, based on a combination of low or high scores on questionnaires on daily hassles and self-reported symptoms, to create four extreme groups. NK cell percentages were different between two of the four groups, only when the analysis was not controlled for gender, life style and endocrine parameters. No evidence was found for a relationship between group membership and NKCA. NKCA, however, was found to differ between men and women and to be associated with percentages of NK cells and intracellular levels of cAMP. Furthermore, the hypothesis was tested, that hormone-induced changes in NKCA in vitro are dependent on the individual's current stress profile. To investigate this issue, NKCA was measured after cells had been incubated with hydrocortisone (10−6 or 10−7 M) or the β-adrenergic agonist isoprenaline (10−5 or 10−7 M) in vitro. Changes in NKCA were found to be related to plasma adrenaline levels, but no evidence was found for involvement of psychological variables. It is concluded that, in the current setting, there is no association between the combination of scores on the two psychological questionnaires, and NKCA or hormone-induced changes therein.
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DOI: 10.1016/0024-3205(93)90002-K
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Duivenvoorden</name><affiliation><mods:affiliation>Erasmus University, Rotterdam, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Ballieux, Rudy E" sort="Ballieux, Rudy E" uniqKey="Ballieux R" first="Rudy E." last="Ballieux">Rudy E. 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Benschop</name><affiliation><mods:affiliation>University of Utrecht, Utrecht, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Jabaaij, Lea" sort="Jabaaij, Lea" uniqKey="Jabaaij L" first="Lea" last="Jabaaij">Lea Jabaaij</name><affiliation><mods:affiliation>University of Utrecht, Utrecht, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Oostveen, Frank G" sort="Oostveen, Frank G" uniqKey="Oostveen F" first="Frank G." last="Oostveen">Frank G. Oostveen</name><affiliation><mods:affiliation>University of Utrecht, Utrecht, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Vingerhoets, Ad J J M" sort="Vingerhoets, Ad J J M" uniqKey="Vingerhoets A" first="Ad J. J. M." last="Vingerhoets">Ad J. J. M. Vingerhoets</name><affiliation><mods:affiliation>The Helen Dowling Institute for Biopsychosocial Medicine, Rotterdam, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Kirschbaum, Clemens" sort="Kirschbaum, Clemens" uniqKey="Kirschbaum C" first="Clemens" last="Kirschbaum">Clemens Kirschbaum</name><affiliation><mods:affiliation>Trier University, Trier, Germany</mods:affiliation></affiliation></author><author><name sortKey="Duivenvoorden, Hugo J" sort="Duivenvoorden, Hugo J" uniqKey="Duivenvoorden H" first="Hugo J." last="Duivenvoorden">Hugo J. Duivenvoorden</name><affiliation><mods:affiliation>Erasmus University, Rotterdam, The Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Ballieux, Rudy E" sort="Ballieux, Rudy E" uniqKey="Ballieux R" first="Rudy E." last="Ballieux">Rudy E. Ballieux</name><affiliation><mods:affiliation>University of Utrecht, Utrecht, The Netherlands</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Life Sciences</title><title level="j" type="abbrev">LFS</title><idno type="ISSN">0024-3205</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1993">1993</date><biblScope unit="volume">52</biblScope><biblScope unit="issue">23</biblScope><biblScope unit="page" from="1825">1825</biblScope><biblScope unit="page" to="1834">1834</biblScope></imprint><idno type="ISSN">0024-3205</idno></series><idno type="istex">48DD9B201BEDE7FF7990B7FA3FA1F1942C7F684A</idno><idno type="DOI">10.1016/0024-3205(93)90002-K</idno><idno type="PII">0024-3205(93)90002-K</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0024-3205</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The present report investigated whether percentages of circulating natural killer (NK) cells and NK cell activity (NKCA) are associated with psychological variables. Subjects (n=95) were selected, based on a combination of low or high scores on questionnaires on daily hassles and self-reported symptoms, to create four extreme groups. NK cell percentages were different between two of the four groups, only when the analysis was not controlled for gender, life style and endocrine parameters. No evidence was found for a relationship between group membership and NKCA. NKCA, however, was found to differ between men and women and to be associated with percentages of NK cells and intracellular levels of cAMP. Furthermore, the hypothesis was tested, that hormone-induced changes in NKCA in vitro are dependent on the individual's current stress profile. To investigate this issue, NKCA was measured after cells had been incubated with hydrocortisone (10−6 or 10−7 M) or the β-adrenergic agonist isoprenaline (10−5 or 10−7 M) in vitro. Changes in NKCA were found to be related to plasma adrenaline levels, but no evidence was found for involvement of psychological variables. It is concluded that, in the current setting, there is no association between the combination of scores on the two psychological questionnaires, and NKCA or hormone-induced changes therein.</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>Robert J. Benschop</name><affiliations><json:string>University of Utrecht, Utrecht, The Netherlands</json:string></affiliations></json:item><json:item><name>Lea Jabaaij</name><affiliations><json:string>University of Utrecht, Utrecht, The Netherlands</json:string></affiliations></json:item><json:item><name>Frank G. Oostveen</name><affiliations><json:string>University of Utrecht, Utrecht, The Netherlands</json:string></affiliations></json:item><json:item><name>Ad J.J.M. Vingerhoets</name><affiliations><json:string>The Helen Dowling Institute for Biopsychosocial Medicine, Rotterdam, The Netherlands</json:string></affiliations></json:item><json:item><name>Clemens Kirschbaum</name><affiliations><json:string>Trier University, Trier, Germany</json:string></affiliations></json:item><json:item><name>Hugo J. Duivenvoorden</name><affiliations><json:string>Erasmus University, Rotterdam, The Netherlands</json:string></affiliations></json:item><json:item><name>Rudy E. Ballieux</name><affiliations><json:string>University of Utrecht, Utrecht, The Netherlands</json:string></affiliations></json:item></author><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>The present report investigated whether percentages of circulating natural killer (NK) cells and NK cell activity (NKCA) are associated with psychological variables. Subjects (n=95) were selected, based on a combination of low or high scores on questionnaires on daily hassles and self-reported symptoms, to create four extreme groups. NK cell percentages were different between two of the four groups, only when the analysis was not controlled for gender, life style and endocrine parameters. No evidence was found for a relationship between group membership and NKCA. NKCA, however, was found to differ between men and women and to be associated with percentages of NK cells and intracellular levels of cAMP. Furthermore, the hypothesis was tested, that hormone-induced changes in NKCA in vitro are dependent on the individual's current stress profile. To investigate this issue, NKCA was measured after cells had been incubated with hydrocortisone (10−6 or 10−7 M) or the β-adrenergic agonist isoprenaline (10−5 or 10−7 M) in vitro. Changes in NKCA were found to be related to plasma adrenaline levels, but no evidence was found for involvement of psychological variables. It is concluded that, in the current setting, there is no association between the combination of scores on the two psychological questionnaires, and NKCA or hormone-induced changes therein.</abstract><qualityIndicators><score>7.996</score><pdfVersion>1.4</pdfVersion><pdfPageSize>497 x 720 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>0</keywordCount><abstractCharCount>1365</abstractCharCount><pdfWordCount>5484</pdfWordCount><pdfCharCount>33295</pdfCharCount><pdfPageCount>10</pdfPageCount><abstractWordCount>208</abstractWordCount></qualityIndicators><title>Psychobiological factors related to human natural killer cell activity and hormonal modulation of NK cells in vitro</title><pii><json:string>0024-3205(93)90002-K</json:string></pii><refBibs><json:item><host><volume>53</volume><pages><last>23</last><first>1</first></pages><author></author><title>Clin. Immunol. 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Immunol.</title></host></json:item></refBibs><genre><json:string>research-article</json:string></genre><host><volume>52</volume><pii><json:string>S0024-3205(00)X1454-3</json:string></pii><pages><last>1834</last><first>1825</first></pages><issn><json:string>0024-3205</json:string></issn><issue>23</issue><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><title>Life Sciences</title><publicationDate>1993</publicationDate></host><categories><wos><json:string>science</json:string><json:string>pharmacology & pharmacy</json:string><json:string>medicine, research & experimental</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>pharmacology & pharmacy</json:string></scienceMetrix></categories><publicationDate>1993</publicationDate><copyrightDate>1993</copyrightDate><doi><json:string>10.1016/0024-3205(93)90002-K</json:string></doi><id>48DD9B201BEDE7FF7990B7FA3FA1F1942C7F684A</id><score>0.8566546</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/48DD9B201BEDE7FF7990B7FA3FA1F1942C7F684A/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/48DD9B201BEDE7FF7990B7FA3FA1F1942C7F684A/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/48DD9B201BEDE7FF7990B7FA3FA1F1942C7F684A/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a">Psychobiological factors related to human natural killer cell activity and hormonal modulation of NK cells in vitro</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>ELSEVIER</p></availability><date>1993</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a">Psychobiological factors related to human natural killer cell activity and hormonal modulation of NK cells in vitro</title><author xml:id="author-1"><persName><forename type="first">Robert J.</forename><surname>Benschop</surname></persName><note type="correspondence"><p>Correspondence to: Robert J. Benschop, Department of Immunology, University Hospital, Room F03.821, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.</p></note><affiliation>University of Utrecht, Utrecht, The Netherlands</affiliation></author><author xml:id="author-2"><persName><forename type="first">Lea</forename><surname>Jabaaij</surname></persName><affiliation>University of Utrecht, Utrecht, The Netherlands</affiliation></author><author xml:id="author-3"><persName><forename type="first">Frank G.</forename><surname>Oostveen</surname></persName><affiliation>University of Utrecht, Utrecht, The Netherlands</affiliation></author><author xml:id="author-4"><persName><forename type="first">Ad J.J.M.</forename><surname>Vingerhoets</surname></persName><affiliation>The Helen Dowling Institute for Biopsychosocial Medicine, Rotterdam, The Netherlands</affiliation></author><author xml:id="author-5"><persName><forename type="first">Clemens</forename><surname>Kirschbaum</surname></persName><affiliation>Trier University, Trier, Germany</affiliation></author><author xml:id="author-6"><persName><forename type="first">Hugo J.</forename><surname>Duivenvoorden</surname></persName><affiliation>Erasmus University, Rotterdam, The Netherlands</affiliation></author><author xml:id="author-7"><persName><forename type="first">Rudy E.</forename><surname>Ballieux</surname></persName><affiliation>University of Utrecht, Utrecht, The Netherlands</affiliation></author></analytic><monogr><title level="j">Life Sciences</title><title level="j" type="abbrev">LFS</title><idno type="pISSN">0024-3205</idno><idno type="PII">S0024-3205(00)X1454-3</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1993"></date><biblScope unit="volume">52</biblScope><biblScope unit="issue">23</biblScope><biblScope unit="page" from="1825">1825</biblScope><biblScope unit="page" to="1834">1834</biblScope></imprint></monogr><idno type="istex">48DD9B201BEDE7FF7990B7FA3FA1F1942C7F684A</idno><idno type="DOI">10.1016/0024-3205(93)90002-K</idno><idno type="PII">0024-3205(93)90002-K</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1993</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The present report investigated whether percentages of circulating natural killer (NK) cells and NK cell activity (NKCA) are associated with psychological variables. Subjects (n=95) were selected, based on a combination of low or high scores on questionnaires on daily hassles and self-reported symptoms, to create four extreme groups. NK cell percentages were different between two of the four groups, only when the analysis was not controlled for gender, life style and endocrine parameters. No evidence was found for a relationship between group membership and NKCA. NKCA, however, was found to differ between men and women and to be associated with percentages of NK cells and intracellular levels of cAMP. Furthermore, the hypothesis was tested, that hormone-induced changes in NKCA in vitro are dependent on the individual's current stress profile. To investigate this issue, NKCA was measured after cells had been incubated with hydrocortisone (10−6 or 10−7 M) or the β-adrenergic agonist isoprenaline (10−5 or 10−7 M) in vitro. Changes in NKCA were found to be related to plasma adrenaline levels, but no evidence was found for involvement of psychological variables. It is concluded that, in the current setting, there is no association between the combination of scores on the two psychological questionnaires, and NKCA or hormone-induced changes therein.</p></abstract></profileDesc><revisionDesc><change when="1993">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/48DD9B201BEDE7FF7990B7FA3FA1F1942C7F684A/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla"><item-info><jid>LFS</jid><aid>9390002K</aid><ce:pii>0024-3205(93)90002-K</ce:pii><ce:doi>10.1016/0024-3205(93)90002-K</ce:doi><ce:copyright type="unknown" year="1993"></ce:copyright></item-info><head><ce:title>Psychobiological factors related to human natural killer cell activity and hormonal modulation of NK cells <ce:italic>in vitro</ce:italic></ce:title><ce:author-group><ce:author><ce:given-name>Robert J.</ce:given-name><ce:surname>Benschop</ce:surname><ce:cross-ref refid="COR1"><ce:sup>∗</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Lea</ce:given-name><ce:surname>Jabaaij</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Frank G.</ce:given-name><ce:surname>Oostveen</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Ad J.J.M.</ce:given-name><ce:surname>Vingerhoets</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Clemens</ce:given-name><ce:surname>Kirschbaum</ce:surname><ce:cross-ref refid="AFF3"><ce:sup>3</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Hugo J.</ce:given-name><ce:surname>Duivenvoorden</ce:surname><ce:cross-ref refid="AFF4"><ce:sup>4</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Rudy E.</ce:given-name><ce:surname>Ballieux</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>a</ce:label><ce:textfn>University of Utrecht, Utrecht, The Netherlands</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>b</ce:label><ce:textfn>The Helen Dowling Institute for Biopsychosocial Medicine, Rotterdam, The Netherlands</ce:textfn></ce:affiliation><ce:affiliation id="AFF3"><ce:label>c</ce:label><ce:textfn>Trier University, Trier, Germany</ce:textfn></ce:affiliation><ce:affiliation id="AFF4"><ce:label>d</ce:label><ce:textfn>Erasmus University, Rotterdam, The Netherlands</ce:textfn></ce:affiliation><ce:correspondence id="COR1"><ce:label>∗</ce:label><ce:text>Correspondence to: Robert J. Benschop, Department of Immunology, University Hospital, Room F03.821, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.</ce:text></ce:correspondence></ce:author-group><ce:date-received day="23" month="3" year="1993"></ce:date-received><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>The present report investigated whether percentages of circulating natural killer (NK) cells and NK cell activity (NKCA) are associated with psychological variables. Subjects (n=95) were selected, based on a combination of low or high scores on questionnaires on daily hassles and self-reported symptoms, to create four extreme groups. NK cell percentages were different between two of the four groups, only when the analysis was not controlled for gender, life style and endocrine parameters. No evidence was found for a relationship between group membership and NKCA. NKCA, however, was found to differ between men and women and to be associated with percentages of NK cells and intracellular levels of cAMP. Furthermore, the hypothesis was tested, that hormone-induced changes in NKCA <ce:italic>in vitro</ce:italic> are dependent on the individual's current stress profile. To investigate this issue, NKCA was measured after cells had been incubated with hydrocortisone (10<ce:sup>−6</ce:sup> or 10<ce:sup>−7</ce:sup> M) or the β-adrenergic agonist isoprenaline (10<ce:sup>−5</ce:sup> or 10<ce:sup>−7</ce:sup> M) <ce:italic>in vitro</ce:italic>. Changes in NKCA were found to be related to plasma adrenaline levels, but no evidence was found for involvement of psychological variables. It is concluded that, in the current setting, there is no association between the combination of scores on the two psychological questionnaires, and NKCA or hormone-induced changes therein.</ce:simple-para></ce:abstract-sec></ce:abstract></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Psychobiological factors related to human natural killer cell activity and hormonal modulation of NK cells in vitro</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Psychobiological factors related to human natural killer cell activity and hormonal modulation of NK cells</title></titleInfo><name type="personal"><namePart type="given">Robert J.</namePart><namePart type="family">Benschop</namePart><affiliation>University of Utrecht, Utrecht, The Netherlands</affiliation><description>Correspondence to: Robert J. Benschop, Department of Immunology, University Hospital, Room F03.821, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Lea</namePart><namePart type="family">Jabaaij</namePart><affiliation>University of Utrecht, Utrecht, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Frank G.</namePart><namePart type="family">Oostveen</namePart><affiliation>University of Utrecht, Utrecht, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ad J.J.M.</namePart><namePart type="family">Vingerhoets</namePart><affiliation>The Helen Dowling Institute for Biopsychosocial Medicine, Rotterdam, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Clemens</namePart><namePart type="family">Kirschbaum</namePart><affiliation>Trier University, Trier, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hugo J.</namePart><namePart type="family">Duivenvoorden</namePart><affiliation>Erasmus University, Rotterdam, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Rudy E.</namePart><namePart type="family">Ballieux</namePart><affiliation>University of Utrecht, Utrecht, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1993</dateIssued><copyrightDate encoding="w3cdtf">1993</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">The present report investigated whether percentages of circulating natural killer (NK) cells and NK cell activity (NKCA) are associated with psychological variables. Subjects (n=95) were selected, based on a combination of low or high scores on questionnaires on daily hassles and self-reported symptoms, to create four extreme groups. NK cell percentages were different between two of the four groups, only when the analysis was not controlled for gender, life style and endocrine parameters. No evidence was found for a relationship between group membership and NKCA. NKCA, however, was found to differ between men and women and to be associated with percentages of NK cells and intracellular levels of cAMP. Furthermore, the hypothesis was tested, that hormone-induced changes in NKCA in vitro are dependent on the individual's current stress profile. To investigate this issue, NKCA was measured after cells had been incubated with hydrocortisone (10−6 or 10−7 M) or the β-adrenergic agonist isoprenaline (10−5 or 10−7 M) in vitro. Changes in NKCA were found to be related to plasma adrenaline levels, but no evidence was found for involvement of psychological variables. It is concluded that, in the current setting, there is no association between the combination of scores on the two psychological questionnaires, and NKCA or hormone-induced changes therein.</abstract><relatedItem type="host"><titleInfo><title>Life Sciences</title></titleInfo><titleInfo type="abbreviated"><title>LFS</title></titleInfo><genre type="journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">1993</dateIssued></originInfo><identifier type="ISSN">0024-3205</identifier><identifier type="PII">S0024-3205(00)X1454-3</identifier><part><date>1993</date><detail type="volume"><number>52</number><caption>vol.</caption></detail><detail type="issue"><number>23</number><caption>no.</caption></detail><extent unit="issue pages"><start>PL255</start><end>PL265</end></extent><extent unit="issue pages"><start>1809</start><end>1897</end></extent><extent unit="pages"><start>1825</start><end>1834</end></extent></part></relatedItem><identifier type="istex">48DD9B201BEDE7FF7990B7FA3FA1F1942C7F684A</identifier><identifier type="DOI">10.1016/0024-3205(93)90002-K</identifier><identifier type="PII">0024-3205(93)90002-K</identifier><recordInfo><recordContentSource>ELSEVIER</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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