Cardiological effects of catecholamine‐secreting tumours
Identifieur interne : 001776 ( Istex/Corpus ); précédent : 001775; suivant : 001777Cardiological effects of catecholamine‐secreting tumours
Auteurs : T. H. Schu Rmeyer ; B. Engeroff ; H. Dralle ; A. Von Zur Mu HlenSource :
- European Journal of Clinical Investigation [ 0014-2972 ] ; 1997-03.
English descriptors
- KwdEn :
Abstract
Correlations between endocrine and cardiological findings were investigated in 106 patients with catecholamine‐secreting tumours during the florid phase of their illness. Endocrine data showed an elevation of urinary catecholamine or vanillylmandelic acid excretion in all but one subject. Hypertension was found in 78%, symptoms of coronary heart disease in 26% and arrhythmias in 20% of the patients. Twelve per cent of the patients came to the hospital with heart attacks, 7% with acute left heart failure and 6% with myocardial infarction. At admission electrocardiograph (ECG) analysis showed a sinus rhythm in 98%, tachycardia > 100 min−1 in 14% and bradycardia <60 min−1 in 10%. In 16% of the ECGs cQT was increased, in 17% the ST segment was lowered and in 37% abnormal T waves occurred. Indices of myocardial hypertrophy such as the Sokolow index, the modified Romhilt–Estes score and the Murphy score were raised in 29%, 19% and 38% respectively. In 23 of 51 (45%) patients echocardiography showed left ventricular hypertrophy, in 16% mitral valve insufficiency and in 24% disturbances of contractility. Comparison of cardiac and endocrine parameters confirm in vitro and animal studies indicating that, in particular, the α‐mimetic noradrenaline (NA) has deleterious effects on the cardiovascular system. Urinary NA, but not adrenaline or dopamine, excretion was significantly higher in constantly hypertensive than in normotensive patients and associated with an elevation of the Sokolow index and the Romhilt–Estes score. Both indices and plasma NA were higher in patients with myocardial hypertrophy and we found a significant correlation between the Romhilt–Estes score and NA excretion.
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DOI: 10.1046/j.1365-2362.1997.850646.x
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Dralle</name><affiliation><mods:affiliation>Abdominal‐ und Transplantationschirurgie, Medizinische Hochschule, Hannover, Germany</mods:affiliation></affiliation></author><author><name sortKey="Von Zur Mu Hlen, A" sort="Von Zur Mu Hlen, A" uniqKey="Von Zur Mu Hlen A" first="A." last="Von Zur Mu Hlen">A. 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Schu Rmeyer</name><affiliation><mods:affiliation>Abteilung fu¨r Endokrinologie and Stoffwechsel, FPP Universita¨t Trier, Trier</mods:affiliation></affiliation><affiliation><mods:affiliation>Abteilungen Klinische Endokrinologie und</mods:affiliation></affiliation></author><author><name sortKey="Engeroff, B" sort="Engeroff, B" uniqKey="Engeroff B" first="B." last="Engeroff">B. Engeroff</name><affiliation><mods:affiliation>Abteilungen Klinische Endokrinologie und</mods:affiliation></affiliation></author><author><name sortKey="Dralle, H" sort="Dralle, H" uniqKey="Dralle H" first="H." last="Dralle">H. Dralle</name><affiliation><mods:affiliation>Abdominal‐ und Transplantationschirurgie, Medizinische Hochschule, Hannover, Germany</mods:affiliation></affiliation></author><author><name sortKey="Von Zur Mu Hlen, A" sort="Von Zur Mu Hlen, A" uniqKey="Von Zur Mu Hlen A" first="A." last="Von Zur Mu Hlen">A. Von Zur Mu Hlen</name><affiliation><mods:affiliation>Abteilungen Klinische Endokrinologie und</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">European Journal of Clinical Investigation</title><title level="j" type="abbrev">European Journal of Clinical Investigation</title><idno type="ISSN">0014-2972</idno><idno type="eISSN">1365-2362</idno><imprint><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford BSL</pubPlace><date type="published" when="1997-03">1997-03</date><biblScope unit="volume">27</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="189">189</biblScope><biblScope unit="page" to="195">195</biblScope></imprint><idno type="ISSN">0014-2972</idno></series><idno type="istex">22D4808DB5C90EF0D8D0E86B7E56CC1ADFC9D7FB</idno><idno type="DOI">10.1046/j.1365-2362.1997.850646.x</idno><idno type="ArticleID">ECI85</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0014-2972</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cardiac failure</term><term>catecholamines</term><term>echocardiography</term><term>electrocardiography</term><term>hypertension</term><term>phaeochromocytoma</term><term>symptoms</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Correlations between endocrine and cardiological findings were investigated in 106 patients with catecholamine‐secreting tumours during the florid phase of their illness. Endocrine data showed an elevation of urinary catecholamine or vanillylmandelic acid excretion in all but one subject. Hypertension was found in 78%, symptoms of coronary heart disease in 26% and arrhythmias in 20% of the patients. Twelve per cent of the patients came to the hospital with heart attacks, 7% with acute left heart failure and 6% with myocardial infarction. At admission electrocardiograph (ECG) analysis showed a sinus rhythm in 98%, tachycardia > 100 min−1 in 14% and bradycardia <60 min−1 in 10%. In 16% of the ECGs cQT was increased, in 17% the ST segment was lowered and in 37% abnormal T waves occurred. Indices of myocardial hypertrophy such as the Sokolow index, the modified Romhilt–Estes score and the Murphy score were raised in 29%, 19% and 38% respectively. In 23 of 51 (45%) patients echocardiography showed left ventricular hypertrophy, in 16% mitral valve insufficiency and in 24% disturbances of contractility. Comparison of cardiac and endocrine parameters confirm in vitro and animal studies indicating that, in particular, the α‐mimetic noradrenaline (NA) has deleterious effects on the cardiovascular system. Urinary NA, but not adrenaline or dopamine, excretion was significantly higher in constantly hypertensive than in normotensive patients and associated with an elevation of the Sokolow index and the Romhilt–Estes score. Both indices and plasma NA were higher in patients with myocardial hypertrophy and we found a significant correlation between the Romhilt–Estes score and NA excretion.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>T. H. SCHU¨RMEYER</name><affiliations><json:string>Abteilung fu¨r Endokrinologie and Stoffwechsel, FPP Universita¨t Trier, Trier</json:string><json:string>Abteilungen Klinische Endokrinologie und</json:string></affiliations></json:item><json:item><name>B. ENGEROFF</name><affiliations><json:string>Abteilungen Klinische Endokrinologie und</json:string></affiliations></json:item><json:item><name>H. DRALLE</name><affiliations><json:string>Abdominal‐ und Transplantationschirurgie, Medizinische Hochschule, Hannover, Germany</json:string></affiliations></json:item><json:item><name>A. VON ZUR MU¨HLEN</name><affiliations><json:string>Abteilungen Klinische Endokrinologie und</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Cardiac failure</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>catecholamines</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>echocardiography</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>electrocardiography</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>hypertension</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>phaeochromocytoma</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>symptoms</value></json:item></subject><articleId><json:string>ECI85</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Correlations between endocrine and cardiological findings were investigated in 106 patients with catecholamine‐secreting tumours during the florid phase of their illness. Endocrine data showed an elevation of urinary catecholamine or vanillylmandelic acid excretion in all but one subject. Hypertension was found in 78%, symptoms of coronary heart disease in 26% and arrhythmias in 20% of the patients. Twelve per cent of the patients came to the hospital with heart attacks, 7% with acute left heart failure and 6% with myocardial infarction. At admission electrocardiograph (ECG) analysis showed a sinus rhythm in 98%, tachycardia > 100 min−1 in 14% and bradycardia >60 min−1 in 10%. In 16% of the ECGs cQT was increased, in 17% the ST segment was lowered and in 37% abnormal T waves occurred. Indices of myocardial hypertrophy such as the Sokolow index, the modified Romhilt–Estes score and the Murphy score were raised in 29%, 19% and 38% respectively. In 23 of 51 (45%) patients echocardiography showed left ventricular hypertrophy, in 16% mitral valve insufficiency and in 24% disturbances of contractility. Comparison of cardiac and endocrine parameters confirm in vitro and animal studies indicating that, in particular, the α‐mimetic noradrenaline (NA) has deleterious effects on the cardiovascular system. Urinary NA, but not adrenaline or dopamine, excretion was significantly higher in constantly hypertensive than in normotensive patients and associated with an elevation of the Sokolow index and the Romhilt–Estes score. Both indices and plasma NA were higher in patients with myocardial hypertrophy and we found a significant correlation between the Romhilt–Estes score and NA excretion.</abstract><qualityIndicators><score>7.38</score><pdfVersion>1.2</pdfVersion><pdfPageSize>596 x 842 pts (A4)</pdfPageSize><refBibsNative>false</refBibsNative><abstractCharCount>1702</abstractCharCount><pdfWordCount>4380</pdfWordCount><pdfCharCount>29454</pdfCharCount><pdfPageCount>7</pdfPageCount><abstractWordCount>254</abstractWordCount></qualityIndicators><title>Cardiological effects of catecholamine‐secreting tumours</title><refBibs><json:item><author><json:item><name>R Garcia</name></json:item><json:item><name>Jm Jennings</name></json:item></author><host><volume>29</volume><pages><last>71</last><first>568</first></pages><author></author><title>Am J Cardiol</title><publicationDate>1972</publicationDate></host><title>Pheochromocytoma masquerading as cardiomyopathy</title><publicationDate>1972</publicationDate></json:item><json:item><author><json:item><name>Pw Leeuu</name></json:item><json:item><name>Fl Waltman</name></json:item><json:item><name>Wh Birkenhager</name></json:item></author><host><pages><last>12</last><first>810</first></pages><author></author><title>Hypertension</title><publicationDate>1986</publicationDate></host><title>Noncardiogenic pulmonary edema as the sole manifestation of pheochromocytoma</title><publicationDate>1986</publicationDate></json:item><json:item><author><json:item><name>Na Yankopulos</name></json:item><json:item><name>Ac Montero</name></json:item><json:item><name>Wg Curd</name></json:item><json:item><name>Me Kahil</name></json:item><json:item><name>Re Condon</name></json:item></author><host><volume>66</volume><pages><last>7</last><first>585</first></pages><author></author><title>Chest</title><publicationDate>1974</publicationDate></host><title>Observation on myocardial function during chronic catecholamine oversecretion</title><publicationDate>1974</publicationDate></json:item><json:item><author><json:item><name>Ik Kline</name></json:item></author><host><volume>38</volume><pages><last>47</last><first>539</first></pages><author></author><title>Am J Pathol</title><publicationDate>1961</publicationDate></host><title>Myocardial alterations associated with pheochromocytomas</title><publicationDate>1961</publicationDate></json:item><json:item><author><json:item><name>Ag Rose</name></json:item></author><host><volume>48</volume><pages><last>9</last><first>1285</first></pages><author></author><title>S Afr Med J</title><publicationDate>1974</publicationDate></host><title>Catecholamine-induced myocardial damage associated with phaeochromocytomas and tetanus</title><publicationDate>1974</publicationDate></json:item><json:item><author><json:item><name>Cd Cohen</name></json:item><json:item><name>Dm Dent</name></json:item></author><host><volume>60</volume><pages><last>15</last><first>111</first></pages><author></author><title>Postgrad Med J</title><publicationDate>1984</publicationDate></host><title>Phaeochromocytoma and acute cardiovascular death (with special reference to myocardial infarction)</title><publicationDate>1984</publicationDate></json:item><json:item><author><json:item><name>G Baker</name></json:item><json:item><name>Nh Zellner</name></json:item><json:item><name>S Weitzner</name></json:item><json:item><name>Sk Leach</name></json:item><json:item><name>Nm Albuquerque</name></json:item></author><host><volume>83</volume><pages><last>93</last><first>688</first></pages><author></author><title>Am Heart J</title><publicationDate>1972</publicationDate></host><title>Pheochromocytoma without hypertension presenting as cardiomyopathy</title><publicationDate>1972</publicationDate></json:item><json:item><author><json:item><name>T Goldbaum</name></json:item><json:item><name>S Henochowicz</name></json:item></author><host><volume>81</volume><pages><last>2</last><first>921</first></pages><author></author><title>Am J Med</title><publicationDate>1986</publicationDate></host><title>Pheochromocytoma presenting with Prinzmetal's angina</title><publicationDate>1986</publicationDate></json:item><json:item><author><json:item><name>U Kaul</name></json:item><json:item><name>Jc Mohan</name></json:item><json:item><name>Ps Rao</name></json:item><json:item><name>S Mukhopahyaya</name></json:item><json:item><name>Sm Sing</name></json:item><json:item><name>Ml Bhatia</name></json:item></author><host><volume>36</volume><pages><last>20</last><first>118</first></pages><author></author><title>Ind Heart J</title><publicationDate>1984</publicationDate></host><title>Pheochromocytoma presenting as recurrent syncope resulting from ventricular tachycardia—an unusual presentation</title><publicationDate>1984</publicationDate></json:item><json:item><author><json:item><name>R Martinez</name></json:item><json:item><name>R Russo</name></json:item><json:item><name>M Lupi</name></json:item><json:item><name>M Federici</name></json:item></author><host><volume>40</volume><pages><last>8</last><first>105</first></pages><author></author><title>Minerva Cardioangiol</title><publicationDate>1992</publicationDate></host><title>Cardiac involvement in pheochromocytoma. A report of 6 cases</title><publicationDate>1992</publicationDate></json:item><json:item><author><json:item><name>Th Schürmeyer</name></json:item><json:item><name>B Engeroff</name></json:item><json:item><name>Von Zur Mühlen</name></json:item><json:item><name>A Dralle</name></json:item><json:item><name>H Symptomatik Und Endokrinologische Befunde Bei Katecholaminsezernierenden Tumoren</name></json:item></author><host><volume>119</volume><pages><last>7</last><first>1721</first></pages><author></author><title>Dtsch Med Wschr</title><publicationDate>1994</publicationDate></host><publicationDate>1994</publicationDate></json:item><json:item><author><json:item><name>D Ratge</name></json:item><json:item><name>G Baumgardt</name></json:item><json:item><name>E Knoll</name></json:item><json:item><name>H Wisser</name></json:item></author><host><volume>132</volume><pages><last>35</last><first>229</first></pages><author></author><title>Clin Chim Acta</title><publicationDate>1983</publicationDate></host><title>Plasma free and conjugated catecholamines in diagnosis and localisation of pheochromocytoma</title><publicationDate>1983</publicationDate></json:item><json:item><author><json:item><name>S Ahnve</name></json:item></author><host><volume>109</volume><pages><last>74</last><first>568</first></pages><author></author><title>Am Heart J</title><publicationDate>1985</publicationDate></host><title>Correction of the QT interval for heart rate: review of different formulas and the use of Bazett's formula in myocardial infarction</title><publicationDate>1985</publicationDate></json:item><json:item><author><json:item><name>M Sokolow</name></json:item><json:item><name>Tp Lyon</name></json:item></author><host><volume>37</volume><pages><last>86</last><first>161</first></pages><author></author><title>Am Heart J</title><publicationDate>1949</publicationDate></host><title>The ventricular complex in left ventricular hypertrophy as obtained by unipolar precordial and limb leads</title><publicationDate>1949</publicationDate></json:item><json:item><author><json:item><name>Dw Romhilt</name></json:item><json:item><name>Eh Estes</name></json:item></author><host><volume>75</volume><pages><last>8</last><first>752</first></pages><author></author><title>Am Heart J</title><publicationDate>1968</publicationDate></host><title>A point score system for the ECG diagnosis of left ventricular hypertrophy</title><publicationDate>1968</publicationDate></json:item><json:item><author><json:item><name>Ml Murphy</name></json:item><json:item><name>Pn Thenabadu</name></json:item><json:item><name>N De Soyza</name></json:item></author><host><volume>53</volume><pages><last>7</last><first>1140</first></pages><author></author><title>Am J Cardiol</title><publicationDate>1984</publicationDate></host><title>Reevaluation of electrocardiographic criteria for left, right and combined cardiac ventricular hypertrophy</title><publicationDate>1984</publicationDate></json:item><json:item><author><json:item><name>Dj Sahn</name></json:item><json:item><name>A Demaria</name></json:item><json:item><name>J Kisslo</name></json:item><json:item><name>A Weyman</name></json:item></author><host><volume>58</volume><pages><last>83</last><first>1072</first></pages><author></author><title>Circulation</title><publicationDate>1978</publicationDate></host><title>Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements</title><publicationDate>1978</publicationDate></json:item><json:item><author><json:item><name>Mh Boldt</name></json:item><json:item><name>M Flexner</name></json:item><json:item><name>Ab Ortner</name></json:item></author><host><volume>46</volume><pages><last>77</last><first>1165</first></pages><author></author><title>Ann Intern Med</title><publicationDate>1957</publicationDate></host><title>Pheochromocytoma associated with painless myocardial infarction</title><publicationDate>1957</publicationDate></json:item><json:item><author><json:item><name>To Cheng</name></json:item></author><host><volume>25</volume><pages><first>16</first></pages><author></author><title>Hosp Pract</title><publicationDate>1990</publicationDate></host><title>Pheochromocytoma as an MI mimic. Letter</title><publicationDate>1990</publicationDate></json:item><json:item><author><json:item><name>To Cheng</name></json:item><json:item><name>Tt Bashour</name></json:item></author><host><volume>70</volume><pages><last>9</last><first>397</first></pages><author></author><title>Chest</title><publicationDate>1976</publicationDate></host><title>Striking electrocardiographic changes associated with pheochromocytoma</title><publicationDate>1976</publicationDate></json:item><json:item><author><json:item><name>Kk Gupta</name></json:item></author><host><volume>1</volume><pages><last>2</last><first>281</first></pages><author></author><title>Lancet</title><publicationDate>1975</publicationDate></host><title>Phaeochromocytoma and myocardial infarction</title><publicationDate>1975</publicationDate></json:item><json:item><author><json:item><name>Pe Mattman</name></json:item></author><host><volume>8</volume><pages><last>30</last><first>426</first></pages><author></author><title>Am J Cardiol</title><publicationDate>1961</publicationDate></host><title>Successful removal of a pheochromocytoma four weeks after acute myocardial infarction</title><publicationDate>1961</publicationDate></json:item><json:item><author><json:item><name>P Mcgonigle</name></json:item><json:item><name>Sw Webb</name></json:item><json:item><name>Aaj Adgey</name></json:item></author><host><volume>286</volume><pages><last>1478</last><first>1477</first></pages><author></author><title>Brit Med J</title><publicationDate>1983</publicationDate></host><title>Pheochromocytoma: an unusual cause of chest pain</title><publicationDate>1983</publicationDate></json:item><json:item><author><json:item><name>Jg Nirgiotis</name></json:item><json:item><name>Rj Andrassy</name></json:item></author><host><volume>83</volume><pages><last>80</last><first>1478</first></pages><author></author><title>South Med J</title><publicationDate>1990</publicationDate></host><title>Pheochromocytoma and acute myocardial infarction</title><publicationDate>1990</publicationDate></json:item><json:item><author><json:item><name>R Pelkonen</name></json:item><json:item><name>E Pitkanen</name></json:item></author><host><volume>173</volume><pages><last>4</last><first>41</first></pages><author></author><title>Acta Med Scand</title><publicationDate>1963</publicationDate></host><title>Unusual electrocardiographic changes in pheochromocytoma</title><publicationDate>1963</publicationDate></json:item><json:item><author><json:item><name>Wm Priest</name></json:item></author><host><volume>2</volume><pages><last>2</last><first>860</first></pages><author></author><title>Br Med J</title><publicationDate>1952</publicationDate></host><title>Pheochromocytoma with fatal myocardial infarction in man aged 22</title><publicationDate>1952</publicationDate></json:item><json:item><author><json:item><name>Rw Wilkins</name></json:item><json:item><name>Wer Greer</name></json:item><json:item><name>Jw Culbertson</name></json:item></author><host><volume>86</volume><pages><last>78</last><first>51</first></pages><author></author><title>Arch Intern Med</title><publicationDate>1950</publicationDate></host><title>Extensive laboratory studies of a patient with pheochromocytoma before and after successful operation</title><publicationDate>1950</publicationDate></json:item><json:item><author><json:item><name>H Yasue</name></json:item><json:item><name>M Touyama</name></json:item><json:item><name>H Kato</name></json:item><json:item><name>S Tanaka</name></json:item><json:item><name>F Akiyama</name></json:item></author><host><volume>91</volume><pages><last>155</last><first>14</first></pages><author></author><title>Am Heart J</title><publicationDate>1976</publicationDate></host><title>Prinzmetal's variant form of angina as a manifestation of alpha-adrenergic receptor-mediated coronary artery spasm: documented by coronary arteriography</title><publicationDate>1976</publicationDate></json:item><json:item><author><json:item><name>We Radtke</name></json:item><json:item><name>Fj Kazmier</name></json:item></author><host><volume>35</volume><pages><last>5</last><first>701</first></pages><author></author><title>Am J Cardiol</title><publicationDate>1975</publicationDate></host><title>Cardiovascular complication of pheochromocytoma crisis</title><publicationDate>1975</publicationDate></json:item><json:item><author><json:item><name>M Salathe</name></json:item><json:item><name>P Weiss</name></json:item><json:item><name>R Ritz</name></json:item></author><host><volume>68</volume><pages><last>8</last><first>527</first></pages><author></author><title>Br Heart J</title><publicationDate>1992</publicationDate></host><title>Rapid reversal of heart failure in a patient with phaeochromocytoma and catecholamine-induced cardiomyopathy who was treated with captopril</title><publicationDate>1992</publicationDate></json:item><json:item><author><json:item><name>Wg Pogson</name></json:item><json:item><name>J Sharma</name></json:item><json:item><name>Tt Crouch</name></json:item></author><host><volume>73</volume><pages><last>8</last><first>795</first></pages><author></author><title>South Med J</title><publicationDate>1980</publicationDate></host><title>Pulmonary edema with lowdose propranolol in pheochromocytoma</title><publicationDate>1980</publicationDate></json:item><json:item><author><json:item><name>Rm Robertson</name></json:item><json:item><name>Ajj Wood</name></json:item><json:item><name>Wk Vaughn</name></json:item><json:item><name>D Robertson</name></json:item></author><host><volume>65</volume><pages><last>5</last><first>281</first></pages><author></author><title>Circulation</title><publicationDate>1982</publicationDate></host><title>Exacerbation of vasotonic angina pectoris by propranolol</title><publicationDate>1982</publicationDate></json:item><json:item><author><json:item><name>Em Sloand</name></json:item><json:item><name>Bt Thompson</name></json:item></author><host><volume>144</volume><pages><last>4</last><first>173</first></pages><author></author><title>Arch Intern Med</title><publicationDate>1984</publicationDate></host><title>Propranolol-induced pulmonary edema and shock in a patient with pheochromocytoma</title><publicationDate>1984</publicationDate></json:item><json:item><author><json:item><name>Rd Michaels</name></json:item><json:item><name>Jh Hays</name></json:item><json:item><name>O Brian</name></json:item><json:item><name>Jt Shakir</name></json:item><json:item><name>Km </name></json:item></author><host><volume>13</volume><pages><last>7</last><first>943</first></pages><author></author><title>J Endocrinol Invest</title><publicationDate>1990</publicationDate></host><title>Pheochromocytoma associated ventricular tachycardia blocked with atenolol</title><publicationDate>1990</publicationDate></json:item><json:item><author><json:item><name>I Balazovjech</name></json:item><json:item><name>J Murin</name></json:item><json:item><name>K Kralova</name></json:item></author><host><volume>93</volume><pages><last>36</last><first>29</first></pages><author></author><title>Exp Clin Endocrinol</title><publicationDate>1989</publicationDate></host><title>Catecholamine heart muscle disease in pheochromocytoma</title><publicationDate>1989</publicationDate></json:item><json:item><author><json:item><name>I Klein</name></json:item><json:item><name>K Ojamaa</name></json:item></author><host><volume>75</volume><pages><last>42</last><first>339</first></pages><author></author><title>J Clin Endocrinol Metab</title><publicationDate>1992</publicationDate></host><title>Clinical review 36: Cardiovascular manifestations of endocrine disease</title><publicationDate>1992</publicationDate></json:item><json:item><author><json:item><name>M Salathe</name></json:item><json:item><name>M Romanens</name></json:item><json:item><name>P Weiss</name></json:item><json:item><name>R Ritz</name></json:item></author><host><volume>122</volume><pages><last>600</last><first>597</first></pages><author></author><title>Schweiz Med Wochenschr</title><publicationDate>1992</publicationDate></host><title>Acute left heart insufficiency: possible leading symptom of a pheochromocytoma</title><publicationDate>1992</publicationDate></json:item><json:item><author><json:item><name>Jp Jiang</name></json:item><json:item><name>Se Downing</name></json:item></author><host><volume>63</volume><pages><last>91</last><first>581</first></pages><author></author><title>Yale J Biol Med</title><publicationDate>1990</publicationDate></host><title>Catecholamine cardiomyopathy: review and analysis of pathogenetic mechanisms</title><publicationDate>1990</publicationDate></json:item><json:item><author><json:item><name>Van Vliet</name></json:item><json:item><name>Pd Burchell</name></json:item><json:item><name>Hb Titus</name></json:item><json:item><name>Jl </name></json:item></author><host><volume>274</volume><pages><last>8</last><first>1102</first></pages><author></author><title>New Engl J Med</title><publicationDate>1966</publicationDate></host><title>Focal myocarditis associated with pheochromocytoma</title><publicationDate>1966</publicationDate></json:item><json:item><author><json:item><name>Rm Pearce</name></json:item></author><host><volume>8</volume><pages><last>9</last><first>400</first></pages><author></author><title>J Exp Med</title><publicationDate>1906</publicationDate></host><title>Experimental myocarditis; a study of the histological changes following intravenous injections of adrenalin</title><publicationDate>1906</publicationDate></json:item><json:item><author><json:item><name>Je Szakacs</name></json:item><json:item><name>B Mehlman</name></json:item></author><host><volume>5</volume><pages><last>27</last><first>619</first></pages><author></author><title>Am J Cardiol</title><publicationDate>1960</publicationDate></host><title>Pathologic changes induced by 1-norepi- nephrine</title><publicationDate>1960</publicationDate></json:item><json:item><author><json:item><name>G Franz</name></json:item></author><host><volume>298</volume><pages><last>52</last><first>743</first></pages><author></author><title>Virchows Arch Pathol Anat</title><publicationDate>1937</publicationDate></host><title>Eine seltene Form von toxischer Myokardschädigung</title><publicationDate>1937</publicationDate></json:item><json:item><author><json:item><name>W Raab</name></json:item></author><host><volume>1</volume><pages><last>225</last><first>188</first></pages><author></author><title>Exp Med Surg</title><publicationDate>1943</publicationDate></host><title>The pathogenic significance of adrenalin and related substances in the heart muscle</title><publicationDate>1943</publicationDate></json:item><json:item><author><json:item><name>M Hausmann</name></json:item><json:item><name>S Getzowa</name></json:item></author><host><volume>52</volume><pages><last>92</last><first>889</first></pages><author></author><title>Schweizer Med Wochenschr</title><publicationDate>1922</publicationDate></host><title>Ein Paragangliom des Zuckerkandl'schen Organs mit gleichzeitiger Herz-und Nierenhypertrophie</title><publicationDate>1922</publicationDate></json:item><json:item><author><json:item><name>J Sode</name></json:item><json:item><name>Lc Getzen</name></json:item><json:item><name>Dp Osborn</name></json:item></author><host><volume>114</volume><pages><last>31</last><first>927</first></pages><author></author><title>Am J Surg</title><publicationDate>1967</publicationDate></host><title>Cardiac arrhythmias and cardiomyopathy associated with pheochromocytoma</title><publicationDate>1967</publicationDate></json:item><json:item><author><json:item><name>F Stecken</name></json:item><json:item><name>A Villeneuve</name></json:item><json:item><name>Jb Gauvain</name></json:item><json:item><name>P Potin</name></json:item><json:item><name>F Therain</name></json:item></author><host><volume>83</volume><pages><last>11</last><first>1607</first></pages><author></author><title>Arch Mal Coeur</title><publicationDate>1990</publicationDate></host><title>Functional coronary insufficiency in pheochromocytoma. Contribution of isotopic tests. A case report</title><publicationDate>1990</publicationDate></json:item><json:item><author><json:item><name>Je Touze</name></json:item><json:item><name>A Monnier</name></json:item><json:item><name>R Bordahandy</name></json:item></author><host><volume>14</volume><pages><last>9</last><first>435</first></pages><author></author><title>Coeur</title><publicationDate>1983</publicationDate></host><title>Myocardite adrénergique mortelle au cours d'un phéochromocytome malin</title><publicationDate>1983</publicationDate></json:item><json:item><author><json:item><name>R Wood</name></json:item><json:item><name>Pj Commerford</name></json:item><json:item><name>Ag Rose</name></json:item><json:item><name>A Tooke</name></json:item></author><host><volume>121</volume><pages><last>13</last><first>610</first></pages><author></author><title>Am Heart J</title><publicationDate>1991</publicationDate></host><title>Reversible catecholamine-induced cardiomyopathy</title><publicationDate>1991</publicationDate></json:item><json:item><author><json:item><name>Am Burgess</name></json:item><json:item><name>Gw Waterman</name></json:item><json:item><name>Fb Cutts</name></json:item></author><host><volume>58</volume><pages><last>47</last><first>433</first></pages><author></author><title>Arch Intern Med</title><publicationDate>1936</publicationDate></host><title>Adrenal sympathic syndrome with unusual variations in cardiac rhythm. Report of a case</title><publicationDate>1936</publicationDate></json:item><json:item><author><json:item><name>P Cannon</name></json:item><json:item><name>T Sjöstrand</name></json:item></author><host><volume>4</volume><pages><last>7</last><first>266</first></pages><author></author><title>Scand J Clin Lab Invest</title><publicationDate>1952</publicationDate></host><title>ECG-changes seen in cases of pheochromocytoma compared with changes experimentally evoked by adrenaline</title><publicationDate>1952</publicationDate></json:item><json:item><author><json:item><name>J Durant</name></json:item></author><host><volume>2</volume><pages><last>6</last><first>124</first></pages><author></author><title>Lancet</title><publicationDate>1993</publicationDate></host><title>Arrhythmic crisis of phaeochromocytoma</title><publicationDate>1993</publicationDate></json:item><json:item><author><json:item><name>T Espersen</name></json:item><json:item><name>E Dahl-Iversen</name></json:item></author><host><volume>94</volume><pages><last>90</last><first>271</first></pages><author></author><title>Acta Chir Scand</title><publicationDate>1946</publicationDate></host><title>The clinical picture and treatment of pheochromocytomas of the suprarenal</title><publicationDate>1946</publicationDate></json:item><json:item><author><json:item><name>C French</name></json:item><json:item><name>Fa Campagna</name></json:item></author><host><volume>55</volume><pages><last>34</last><first>127</first></pages><author></author><title>Ann Intern Med</title><publicationDate>1961</publicationDate></host><title>Pheochromocytoma with shock, marked leucocytosis, and unusual electrocardiograms. Case report and review of the literature</title><publicationDate>1961</publicationDate></json:item><json:item><author><json:item><name>R Hegglin</name></json:item><json:item><name>M Holzmann</name></json:item></author><host><volume>180</volume><pages><last>91</last><first>681</first></pages><author></author><title>Dtsch Arch Klin Med</title><publicationDate>1937</publicationDate></host><title>Elektrokardiographische Befunde beim Paragangliom der Nebennieren</title><publicationDate>1937</publicationDate></json:item><json:item><author><json:item><name>R Mornex</name></json:item><json:item><name>A Perrin</name></json:item><json:item><name>A Saint-Pierre</name></json:item><json:item><name>L Peyrin</name></json:item><json:item><name>C Age</name></json:item></author><host><volume>18</volume><pages><last>61</last><first>553</first></pages><author></author><title>Rev Lyon Med</title><publicationDate>1969</publicationDate></host><title>Phéochromocytome avec troubles isolés du rythme cardiaque</title><publicationDate>1969</publicationDate></json:item><json:item><author><json:item><name>Tc Northfield</name></json:item></author><host><volume>29</volume><pages><last>93</last><first>588</first></pages><author></author><title>Br Heart J</title><publicationDate>1967</publicationDate></host><title>Cardiac complications of phaeochromocytoma</title><publicationDate>1967</publicationDate></json:item><json:item><author><json:item><name>Hg Ouzts</name></json:item><json:item><name>Hr Newland</name></json:item></author><host><volume>103</volume><pages><last>4</last><first>923</first></pages><author></author><title>Am Heart J</title><publicationDate>1982</publicationDate></host><title>Cardiac arrest in pheochromocytoma</title><publicationDate>1982</publicationDate></json:item><json:item><author><json:item><name>A 58 Saint-Pierre</name></json:item><json:item><name>C Lejosne</name></json:item><json:item><name>A Perrin</name></json:item></author><host><volume>13</volume><pages><last>73</last><first>59</first></pages><author></author><title>Coeur Med Int</title><publicationDate>1975</publicationDate></host><title>Aspects e ´lectrocardiographiques des phéochromocytomes</title><publicationDate>1975</publicationDate></json:item><json:item><author><json:item><name>Wj Sayer</name></json:item><json:item><name>M Moser</name></json:item><json:item><name>Tw Mattingly</name></json:item></author><host><volume>48</volume><pages><last>53</last><first>42</first></pages><author></author><title>Am Heart J</title><publicationDate>1954</publicationDate></host><title>Pheochromocytoma and the abnormal electrocardiogram</title><publicationDate>1954</publicationDate></json:item><json:item><author><json:item><name>Jl Sierra-Callejas</name></json:item></author><host><volume>99</volume><pages><last>6</last><first>2405</first></pages><author></author><title>Dtsch Med Wochenschr</title><publicationDate>1974</publicationDate></host><title>Katecholamin-aktive Myokarditis bei Phäochromozytom</title><publicationDate>1974</publicationDate></json:item><json:item><author><json:item><name>Hw Bucher</name></json:item><json:item><name>R Aepli</name></json:item><json:item><name>F Zenger</name></json:item><json:item><name>P Stucki</name></json:item></author><host><volume>99</volume><pages><last>60</last><first>956</first></pages><author></author><title>Schweizer Med Wschr</title><publicationDate>1969</publicationDate></host><title>Phäochromozytom mit außergewöhnlichen Herzrhythmusstörungen und ihre Behandlung mit a-und b-Rezeptoren-Blockern</title><publicationDate>1969</publicationDate></json:item><json:item><author><json:item><name>Sk Huang</name></json:item><json:item><name>Mj Rosenberg</name></json:item><json:item><name>P Denes</name></json:item></author><host><volume>3</volume><pages><last>5</last><first>872</first></pages><author></author><title>JACC</title><publicationDate>1984</publicationDate></host><title>Short PR interval and narrow QR3 complex associated with pheochromocytoma: electrophysiologic observations</title><publicationDate>1984</publicationDate></json:item><json:item><author><json:item><name>Ja Abildskov</name></json:item></author><host><volume>30</volume><pages><last>9</last><first>171</first></pages><author></author><title>Annu Rev Med</title><publicationDate>1979</publicationDate></host><title>The prolonged QT interval</title><publicationDate>1979</publicationDate></json:item><json:item><author><json:item><name>G Stenström</name></json:item><json:item><name>K Swedberg</name></json:item><json:item><name> Qrs</name></json:item></author><host><volume>224</volume><pages><last>5</last><first>231</first></pages><author></author><title>Acta Med Scand</title><publicationDate>1988</publicationDate></host><title>QTc intervals and ECG abnormalities in pheochromocytoma patients before, during and after treatment</title><publicationDate>1988</publicationDate></json:item><json:item><author><json:item><name>Jb Graham</name></json:item></author><host><volume>92</volume><pages><last>21</last><first>105</first></pages><author></author><title>Int Abst Surg</title><publicationDate>1951</publicationDate></host><title>Pheochromocytoma and hypertension</title><publicationDate>1951</publicationDate></json:item><json:item><author><json:item><name>K Iizuka</name></json:item><json:item><name>M Makiguchi</name></json:item><json:item><name>Y Suzuki</name></json:item></author><host><volume>39</volume><pages><last>82</last><first>279</first></pages><author></author><title>Kokyu To Junkan</title><publicationDate>1991</publicationDate></host><title>Postural ventricular tachycardia in patients with pheochromocytoma</title><publicationDate>1991</publicationDate></json:item><json:item><author><json:item><name>Hu Bramann</name></json:item><json:item><name>W Zidek</name></json:item><json:item><name>H Vetter</name></json:item></author><host><volume>72</volume><pages><last>5</last><first>163</first></pages><author></author><title>Cardiology</title><publicationDate>1985</publicationDate></host><title>Long term ECG in pheochromocytoma</title><publicationDate>1985</publicationDate></json:item><json:item><author><json:item><name>B Dabrowska</name></json:item><json:item><name>T Feltynowski</name></json:item><json:item><name>B Wocial</name></json:item><json:item><name>W Szpak</name></json:item><json:item><name>W Januszewicz</name></json:item></author><host><volume>4</volume><pages><last>9</last><first>397</first></pages><author></author><title>J Hum Hypertens</title><publicationDate>1990</publicationDate></host><title>Effect of removal of phaeochromocytoma on diurnal variability of blood pressure, heart rhythm and excretion of catecholamines</title><publicationDate>1990</publicationDate></json:item><json:item><author><json:item><name>Ja Abildskov</name></json:item></author><host><volume>92</volume><pages><last>16</last><first>210</first></pages><author></author><title>Am Heart J</title><publicationDate>1976</publicationDate></host><title>Adrenergic effects on the QT interval of the electrocardiogram</title><publicationDate>1976</publicationDate></json:item><json:item><author><json:item><name>Ac Barger</name></json:item><json:item><name>Ja Herd</name></json:item><json:item><name>Mr Liebowitz</name></json:item></author><host><volume>107</volume><pages><last>7</last><first>474</first></pages><author></author><title>Proc Soc Exp Biol Med</title><publicationDate>1961</publicationDate></host><title>Chronic catheterization of coronary artery: Induction of ECG pattern of myocardial ischemia by intracoronary epinephrine</title><publicationDate>1961</publicationDate></json:item><json:item><author><json:item><name>E Lepeschkin</name></json:item><json:item><name>H Marchet</name></json:item><json:item><name>G Schroeder</name></json:item><json:item><name>R Wagner</name></json:item><json:item><name>P De Paula E Silva</name></json:item><json:item><name>W Raab</name></json:item></author><host><pages><last>603</last><first>594</first></pages><author></author><title>Am J Cardiol</title><publicationDate>1960</publicationDate></host><title>Effect of epinephrine and norepinephrine on the electrocardiogram of 100 normal subjects</title><publicationDate>1960</publicationDate></json:item><json:item><author><json:item><name>Aj Miller</name></json:item><json:item><name>To Cheng</name></json:item><json:item><name>Me Freeman</name></json:item></author><host><volume>50</volume><pages><last>76</last><first>567</first></pages><author></author><title>Am Heart J</title><publicationDate>1956</publicationDate></host><title>Electrocardiographic changes during norepinephrine-induced hypertension in normal man</title><publicationDate>1956</publicationDate></json:item><json:item><host><pages><last>4</last><first>861</first></pages><author><json:item><name>P Tcherdakoff</name></json:item><json:item><name>G Simoni</name></json:item><json:item><name>P Milliez</name></json:item></author><title>Caractères e ´volutifs du phéochromocytome Etude de 42 cas personnels</title><publicationDate>1974</publicationDate></host></json:item><json:item><author><json:item><name>Pjm Sloan</name></json:item><json:item><name>Dg Beevers</name></json:item></author><host><volume>4</volume><pages><last>22</last><first>215</first></pages><author></author><title>Eur Heart J</title><publicationDate>1983</publicationDate></host><title>Hypertension and the heart. A review</title><publicationDate>1983</publicationDate></json:item><json:item><author><json:item><name>M Mardini</name></json:item></author><host><volume>81</volume><pages><last>955</last><first>394</first></pages><author></author><title>Chest</title><publicationDate>1982</publicationDate></host><title>Echocardiographic findings in pheochromocytoma</title><publicationDate>1982</publicationDate></json:item><json:item><author><json:item><name>C Shub</name></json:item><json:item><name>L Cueto-Garcia</name></json:item><json:item><name>Sg Sheps</name></json:item><json:item><name>Dm Ilstrup</name></json:item><json:item><name>Aj Tajik</name></json:item></author><host><volume>57</volume><pages><last>5</last><first>971</first></pages><author></author><title>Am J Cardiol</title><publicationDate>1986</publicationDate></host><title>Echocardiographic findings in pheochromocytoma</title><publicationDate>1986</publicationDate></json:item><json:item><author><json:item><name>Rj Hicks</name></json:item><json:item><name>B Wood</name></json:item><json:item><name>V Kalff</name></json:item><json:item><name>St Anderson</name></json:item><json:item><name>Mj Kelly</name></json:item></author><host><volume>16</volume><pages><last>16</last><first>413</first></pages><author></author><title>Clin Nucl Med</title><publicationDate>1991</publicationDate></host><title>Normalization of left ventricular ejection fraction following resection of pheochromocytoma in a patient with dilated cardiomyopathy</title><publicationDate>1991</publicationDate></json:item><json:item><author><json:item><name>M Schaffer</name></json:item><json:item><name>P Zuberbuhler</name></json:item><json:item><name>G Wilson</name></json:item></author><host><volume>99</volume><pages><last>9</last><first>276</first></pages><author></author><title>J Pediatr</title><publicationDate>1981</publicationDate></host><title>Catecholamine cardiomyopathy: an unusual presentation of pheochromocytoma in children</title><publicationDate>1981</publicationDate></json:item><json:item><author><json:item><name>I Scott</name></json:item><json:item><name>R Parkes</name></json:item><json:item><name>Dp Cameron</name></json:item></author><host><volume>148</volume><pages><last>6</last><first>94</first></pages><author></author><title>Med J Aust</title><publicationDate>1988</publicationDate></host><title>Phaeochromocytoma and cardiomyopathy</title><publicationDate>1988</publicationDate></json:item><json:item><host><author><json:item><name>T,H Schuschu¨schu¨rmeyer</name></json:item></author></host></json:item><json:item><author><json:item><name>Ltd Blackwell Science</name></json:item></author><host><volume>27</volume><pages><last>195</last><first>189</first></pages><author></author><title>European Journal of Clinical Investigation</title></host></json:item><json:item><author><json:item><name>L Shapiro</name></json:item><json:item><name>N Trethowan</name></json:item><json:item><name>S Singh</name></json:item></author><host><volume>58</volume><pages><last>12</last><first>110</first></pages><author></author><title>Postgrad Med J</title><publicationDate>1982</publicationDate></host><title>Normotensive cardiomyopathy and malignant hypertension in pheochromocytoma</title><publicationDate>1982</publicationDate></json:item><json:item><author><json:item><name>Fm Fouad-Tarazi</name></json:item><json:item><name>M Imamura</name></json:item><json:item><name>El Bravo</name></json:item></author><host><volume>5</volume><pages><last>40</last><first>134</first></pages><author></author><title>Am J Hypertens</title><publicationDate>1992</publicationDate></host><title>Differences in left ventricular structural and functional changes between pheochromocytoma and essential hypertension. Role of elevated circulating catecholamines</title><publicationDate>1992</publicationDate></json:item><json:item><author><json:item><name>Jc Lee</name></json:item><json:item><name>Dp Sponenberg</name></json:item></author><host><volume>121</volume><pages><last>21</last><first>316</first></pages><author></author><title>Am J Pathol</title><publicationDate>1985</publicationDate></host><title>Role of a1-adrenoceptors in norepinephrine-induced cardiomyopathy</title><publicationDate>1985</publicationDate></json:item><json:item><author><json:item><name>G Stenström</name></json:item><json:item><name>I Ernest</name></json:item><json:item><name>Le Tisell</name></json:item></author><host><volume>223</volume><pages><last>52</last><first>345</first></pages><author></author><title>Acta Med Scand</title><publicationDate>1988</publicationDate></host><title>Long-term results in 64 patients operated upon for pheochromocytoma</title><publicationDate>1988</publicationDate></json:item><json:item><author><json:item><name>Ev Allen</name></json:item><json:item><name>Wg Bannon</name></json:item><json:item><name>M Upson</name></json:item><json:item><name>Ka Huizenga</name></json:item><json:item><name>Ja Bastron</name></json:item><json:item><name>Jm Waugh</name></json:item></author><host><volume>64</volume><pages><last>20</last><first>109</first></pages><author></author><title>Trans Assoc Am Physicians</title><publicationDate>1951</publicationDate></host><title>A new sympatholytic and adrenolytic drug: clinical studies on pheochromocytoma and essential hypertension</title><publicationDate>1951</publicationDate></json:item><json:item><author><json:item><name>Bk Armstrong</name></json:item><json:item><name>Pg Beahan</name></json:item><json:item><name>Rl Leedman</name></json:item></author><host><volume>4</volume><pages><last>4</last><first>402</first></pages><author></author><title>Aust N Z J Med</title><publicationDate>1972</publicationDate></host><title>Phaeochromocytoma with catecholamine cardiomyopathy successfully treated surgically</title><publicationDate>1972</publicationDate></json:item><json:item><author><json:item><name>M Hamada</name></json:item><json:item><name>T Ito</name></json:item><json:item><name>K Hiwada</name></json:item><json:item><name>T Kokubu</name></json:item><json:item><name>A Genda</name></json:item><json:item><name>R Takeda</name></json:item></author><host><volume>55</volume><pages><last>26</last><first>417</first></pages><author></author><title>Jpn Circ J</title><publicationDate>1991</publicationDate></host><title>Characteristics of systolic time intervals in patients with pheochromocytoma</title><publicationDate>1991</publicationDate></json:item><json:item><author><json:item><name>Jg Wiswell</name></json:item><json:item><name>Rm Crago</name></json:item></author><host><volume>80</volume><pages><last>95</last><first>185</first></pages><author></author><title>Trans Clin Climat Assoc</title><publicationDate>1968</publicationDate></host><title>Reversible cardiomyopathy with pheochromocytoma</title><publicationDate>1968</publicationDate></json:item><json:item><author><json:item><name>El Bravo</name></json:item></author><host><volume>15</volume><pages><last>68</last><first>356</first></pages><author></author><title>Endocrine Rev</title><publicationDate>1994</publicationDate></host><title>Evolving concepts in the pathophysiology, diagnosis, and treatment of pheochromocytoma</title><publicationDate>1994</publicationDate></json:item><json:item><host><author><json:item><name>Cardiological Effects</name></json:item><json:item><name> Catecholamine-Secreting</name></json:item><json:item><name> Tumours</name></json:item></author></host></json:item><json:item><author><json:item><name>Ltd Blackwell Science</name></json:item></author><host><volume>27</volume><pages><last>195</last><first>189</first></pages><author></author><title>European Journal of Clinical Investigation</title></host></json:item></refBibs><genre><json:string>article</json:string></genre><host><volume>27</volume><publisherId><json:string>ECI</json:string></publisherId><pages><total>7</total><last>195</last><first>189</first></pages><issn><json:string>0014-2972</json:string></issn><issue>3</issue><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1365-2362</json:string></eissn><title>European Journal of Clinical Investigation</title><doi><json:string>10.1111/(ISSN)1365-2362</json:string></doi></host><categories><wos><json:string>science</json:string><json:string>medicine, research & experimental</json:string><json:string>medicine, general & internal</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>general clinical medicine</json:string></scienceMetrix></categories><publicationDate>1997</publicationDate><copyrightDate>1997</copyrightDate><doi><json:string>10.1046/j.1365-2362.1997.850646.x</json:string></doi><id>22D4808DB5C90EF0D8D0E86B7E56CC1ADFC9D7FB</id><score>0.91041493</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/22D4808DB5C90EF0D8D0E86B7E56CC1ADFC9D7FB/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/22D4808DB5C90EF0D8D0E86B7E56CC1ADFC9D7FB/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/22D4808DB5C90EF0D8D0E86B7E56CC1ADFC9D7FB/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Cardiological effects of catecholamine‐secreting tumours</title><respStmt><resp>Références bibliographiques récupérées via GROBID</resp><name resp="ISTEX-API">ISTEX-API (INIST-CNRS)</name></respStmt><respStmt><resp>Références bibliographiques récupérées via GROBID</resp><name resp="ISTEX-API">ISTEX-API (INIST-CNRS)</name></respStmt></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford BSL</pubPlace><availability><p>Blackwell Science Ltd, Oxford</p></availability><date>1997</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Cardiological effects of catecholamine‐secreting tumours</title><author xml:id="author-1"><persName><forename type="first">T. H.</forename><surname>SCHU¨RMEYER</surname></persName><affiliation>Abteilung fu¨r Endokrinologie and Stoffwechsel, FPP Universita¨t Trier, Trier</affiliation><affiliation>Abteilungen Klinische Endokrinologie und</affiliation></author><author xml:id="author-2"><persName><forename type="first">B.</forename><surname>ENGEROFF</surname></persName><affiliation>Abteilungen Klinische Endokrinologie und</affiliation></author><author xml:id="author-3"><persName><forename type="first">H.</forename><surname>DRALLE</surname></persName><affiliation>Abdominal‐ und Transplantationschirurgie, Medizinische Hochschule, Hannover, Germany</affiliation></author><author xml:id="author-4"><persName><forename type="first">A.</forename><surname>VON ZUR MU¨HLEN</surname></persName><affiliation>Abteilungen Klinische Endokrinologie und</affiliation></author></analytic><monogr><title level="j">European Journal of Clinical Investigation</title><title level="j" type="abbrev">European Journal of Clinical Investigation</title><idno type="pISSN">0014-2972</idno><idno type="eISSN">1365-2362</idno><idno type="DOI">10.1111/(ISSN)1365-2362</idno><imprint><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford BSL</pubPlace><date type="published" when="1997-03"></date><biblScope unit="volume">27</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="189">189</biblScope><biblScope unit="page" to="195">195</biblScope></imprint></monogr><idno type="istex">22D4808DB5C90EF0D8D0E86B7E56CC1ADFC9D7FB</idno><idno type="DOI">10.1046/j.1365-2362.1997.850646.x</idno><idno type="ArticleID">ECI85</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1997</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Correlations between endocrine and cardiological findings were investigated in 106 patients with catecholamine‐secreting tumours during the florid phase of their illness. Endocrine data showed an elevation of urinary catecholamine or vanillylmandelic acid excretion in all but one subject. Hypertension was found in 78%, symptoms of coronary heart disease in 26% and arrhythmias in 20% of the patients. Twelve per cent of the patients came to the hospital with heart attacks, 7% with acute left heart failure and 6% with myocardial infarction. At admission electrocardiograph (ECG) analysis showed a sinus rhythm in 98%, tachycardia > 100 min−1 in 14% and bradycardia <60 min−1 in 10%. In 16% of the ECGs cQT was increased, in 17% the ST segment was lowered and in 37% abnormal T waves occurred. Indices of myocardial hypertrophy such as the Sokolow index, the modified Romhilt–Estes score and the Murphy score were raised in 29%, 19% and 38% respectively. In 23 of 51 (45%) patients echocardiography showed left ventricular hypertrophy, in 16% mitral valve insufficiency and in 24% disturbances of contractility. Comparison of cardiac and endocrine parameters confirm in vitro and animal studies indicating that, in particular, the α‐mimetic noradrenaline (NA) has deleterious effects on the cardiovascular system. Urinary NA, but not adrenaline or dopamine, excretion was significantly higher in constantly hypertensive than in normotensive patients and associated with an elevation of the Sokolow index and the Romhilt–Estes score. Both indices and plasma NA were higher in patients with myocardial hypertrophy and we found a significant correlation between the Romhilt–Estes score and NA excretion.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>keywords</head><item><term>Cardiac failure</term></item><item><term>catecholamines</term></item><item><term>echocardiography</term></item><item><term>electrocardiography</term></item><item><term>hypertension</term></item><item><term>phaeochromocytoma</term></item><item><term>symptoms</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1997-03">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2016-12-13">References added</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2017-02-9">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/22D4808DB5C90EF0D8D0E86B7E56CC1ADFC9D7FB/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley component found"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Science Ltd</publisherName><publisherLoc>Oxford BSL</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1365-2362</doi><issn type="print">0014-2972</issn><issn type="electronic">1365-2362</issn><idGroup><id type="product" value="ECI"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="EUROPEAN JOURNAL OF CLINICAL INVESTIGATION">European Journal of Clinical Investigation</title><title type="short">European Journal of Clinical Investigation</title></titleGroup></publicationMeta><publicationMeta level="part" position="03003"><doi origin="wiley">10.1111/eci.1997.27.issue-3</doi><numberingGroup><numbering type="journalVolume" number="27">27</numbering><numbering type="journalIssue" number="3">3</numbering></numberingGroup><coverDate startDate="1997-03">March 1997</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="0018900" status="forIssue"><doi origin="wiley">10.1046/j.1365-2362.1997.850646.x</doi><idGroup><id type="unit" value="ECI85"></id></idGroup><countGroup><count type="pageTotal" number="7"></count></countGroup><titleGroup><title type="tocHeading1">Original Articles</title></titleGroup><copyright>Blackwell Science Ltd, Oxford</copyright><eventGroup><event type="firstOnline" date="2003-11-14"></event><event type="publishedOnlineFinalForm" date="2003-11-14"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.15 mode:FullText" date="2010-07-23"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-20"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-17"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="189">189</numbering><numbering type="pageLast" number="195">195</numbering></numberingGroup><correspondenceTo>T. H. Schu¨rmeyer Department of Endocrinology and Metabolism, Trier University, FPP, D‐54283 Trier, Germany.</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:ECI.ECI85.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="0"></count><count type="referenceTotal" number="0"></count><count type="wordTotal" number="4653"></count><count type="linksPubMed" number="0"></count><count type="linksCrossRef" number="0"></count></countGroup><titleGroup><title type="main"><b>Cardiological effects of catecholamine‐secreting tumours</b></title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1 #a2"><personName><givenNames>T. 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Endocrine data showed an elevation of urinary catecholamine or vanillylmandelic acid excretion in all but one subject. Hypertension was found in 78%, symptoms of coronary heart disease in 26% and arrhythmias in 20% of the patients. Twelve per cent of the patients came to the hospital with heart attacks, 7% with acute left heart failure and 6% with myocardial infarction. At admission electrocardiograph (ECG) analysis showed a sinus rhythm in 98%, tachycardia > 100 min<sup>−1</sup> in 14% and bradycardia <60 min<sup>−1</sup> in 10%. In 16% of the ECGs cQT was increased, in 17% the ST segment was lowered and in 37% abnormal T waves occurred. Indices of myocardial hypertrophy such as the Sokolow index, the modified Romhilt–Estes score and the Murphy score were raised in 29%, 19% and 38% respectively. In 23 of 51 (45%) patients echocardiography showed left ventricular hypertrophy, in 16% mitral valve insufficiency and in 24% disturbances of contractility. Comparison of cardiac and endocrine parameters confirm <i>in vitro</i> and animal studies indicating that, in particular, the α‐mimetic noradrenaline (NA) has deleterious effects on the cardiovascular system. Urinary NA, but not adrenaline or dopamine, excretion was significantly higher in constantly hypertensive than in normotensive patients and associated with an elevation of the Sokolow index and the Romhilt–Estes score. Both indices and plasma NA were higher in patients with myocardial hypertrophy and we found a significant correlation between the Romhilt–Estes score and NA excretion.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Cardiological effects of catecholamine‐secreting tumours</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Cardiological effects of catecholamine‐secreting tumours</title></titleInfo><name type="personal"><namePart type="given">T. 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Endocrine data showed an elevation of urinary catecholamine or vanillylmandelic acid excretion in all but one subject. Hypertension was found in 78%, symptoms of coronary heart disease in 26% and arrhythmias in 20% of the patients. Twelve per cent of the patients came to the hospital with heart attacks, 7% with acute left heart failure and 6% with myocardial infarction. At admission electrocardiograph (ECG) analysis showed a sinus rhythm in 98%, tachycardia > 100 min−1 in 14% and bradycardia <60 min−1 in 10%. In 16% of the ECGs cQT was increased, in 17% the ST segment was lowered and in 37% abnormal T waves occurred. Indices of myocardial hypertrophy such as the Sokolow index, the modified Romhilt–Estes score and the Murphy score were raised in 29%, 19% and 38% respectively. In 23 of 51 (45%) patients echocardiography showed left ventricular hypertrophy, in 16% mitral valve insufficiency and in 24% disturbances of contractility. Comparison of cardiac and endocrine parameters confirm in vitro and animal studies indicating that, in particular, the α‐mimetic noradrenaline (NA) has deleterious effects on the cardiovascular system. Urinary NA, but not adrenaline or dopamine, excretion was significantly higher in constantly hypertensive than in normotensive patients and associated with an elevation of the Sokolow index and the Romhilt–Estes score. Both indices and plasma NA were higher in patients with myocardial hypertrophy and we found a significant correlation between the Romhilt–Estes score and NA excretion.</abstract><subject lang="en"><genre>keywords</genre><topic>Cardiac failure</topic><topic>catecholamines</topic><topic>echocardiography</topic><topic>electrocardiography</topic><topic>hypertension</topic><topic>phaeochromocytoma</topic><topic>symptoms</topic></subject><relatedItem type="host"><titleInfo><title>European Journal of Clinical Investigation</title></titleInfo><titleInfo type="abbreviated"><title>European Journal of Clinical Investigation</title></titleInfo><genre type="journal">journal</genre><identifier type="ISSN">0014-2972</identifier><identifier type="eISSN">1365-2362</identifier><identifier type="DOI">10.1111/(ISSN)1365-2362</identifier><identifier type="PublisherID">ECI</identifier><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>27</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>189</start><end>195</end><total>7</total></extent></part></relatedItem><identifier type="istex">22D4808DB5C90EF0D8D0E86B7E56CC1ADFC9D7FB</identifier><identifier type="DOI">10.1046/j.1365-2362.1997.850646.x</identifier><identifier type="ArticleID">ECI85</identifier><accessCondition type="use and reproduction" contentType="copyright">Blackwell Science Ltd, Oxford</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Science Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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