It's not that bad: Error introduced by oral stimulants in salivary cortisol research
Identifieur interne : 001660 ( Istex/Corpus ); précédent : 001659; suivant : 001661It's not that bad: Error introduced by oral stimulants in salivary cortisol research
Auteurs : Nicole M. Talge ; Bonny Donzella ; Erin M. Kryzer ; Andrea Gierens ; Megan R. GunnarSource :
- Developmental Psychobiology [ 0012-1630 ] ; 2005-12.
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Abstract
Evidence that oral stimulants can produce interference effects in salivary cortisol assays has led to advice to avoid their use. However, in studies with young children, the use of these saliva‐producing substances increases compliance with collection procedures. Four experiments are described to examine the effects of two commonly used stimulants, SweetTarts™ and Koolaid™. Across these experiments, interference effects produced by different quantities of these stimulants (0.025, 0.1, and 0.2 g) and those produced in two commonly used assays, DELFIA and EIA, were explored. The impact of using cotton rolls soaked with an oral stimulant prior to saliva collection was also examined. In general, oral stimulants did not affect the rank ordering of cortisol values, as the results for stimulant‐treated samples were highly correlated with those of untreated samples (approximately .90 for serially collected samples and .95 for aliquots of the same saliva pool). Depending on which assay was used, however, oral stimulants increased or decreased the cortisol levels reported, with effects sizes in the small to medium range. Thus, oral stimulants should not be used with only a portion of the subjects in a study, nor should researchers assay stimulant‐treated samples from the same study using different assays. When used sparingly, oral stimulants can be employed without compromising the quality of salivary cortisol data. © 2005 Wiley Periodicals, Inc. Dev Psychobiol 47: 369–376, 2005.
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DOI: 10.1002/dev.20097
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ISTEX:AC04EE88EEADD252E1BE683DE5FDCAF95E36298CLe document en format XML
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Talge</name><affiliation><mods:affiliation>Institute of Child Development, University of Minnesota, Minneapolis, MN</mods:affiliation></affiliation></author><author><name sortKey="Donzella, Bonny" sort="Donzella, Bonny" uniqKey="Donzella B" first="Bonny" last="Donzella">Bonny Donzella</name><affiliation><mods:affiliation>Institute of Child Development, University of Minnesota, Minneapolis, MN</mods:affiliation></affiliation></author><author><name sortKey="Kryzer, Erin M" sort="Kryzer, Erin M" uniqKey="Kryzer E" first="Erin M." last="Kryzer">Erin M. 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Psychobiol.</title><idno type="ISSN">0012-1630</idno><idno type="eISSN">1098-2302</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2005-12">2005-12</date><biblScope unit="volume">47</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="369">369</biblScope><biblScope unit="page" to="376">376</biblScope></imprint><idno type="ISSN">0012-1630</idno></series><idno type="istex">AC04EE88EEADD252E1BE683DE5FDCAF95E36298C</idno><idno type="DOI">10.1002/dev.20097</idno><idno type="ArticleID">DEV20097</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0012-1630</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>children</term><term>methods</term><term>salivary cortisol</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Evidence that oral stimulants can produce interference effects in salivary cortisol assays has led to advice to avoid their use. However, in studies with young children, the use of these saliva‐producing substances increases compliance with collection procedures. Four experiments are described to examine the effects of two commonly used stimulants, SweetTarts™ and Koolaid™. Across these experiments, interference effects produced by different quantities of these stimulants (0.025, 0.1, and 0.2 g) and those produced in two commonly used assays, DELFIA and EIA, were explored. The impact of using cotton rolls soaked with an oral stimulant prior to saliva collection was also examined. In general, oral stimulants did not affect the rank ordering of cortisol values, as the results for stimulant‐treated samples were highly correlated with those of untreated samples (approximately .90 for serially collected samples and .95 for aliquots of the same saliva pool). Depending on which assay was used, however, oral stimulants increased or decreased the cortisol levels reported, with effects sizes in the small to medium range. Thus, oral stimulants should not be used with only a portion of the subjects in a study, nor should researchers assay stimulant‐treated samples from the same study using different assays. When used sparingly, oral stimulants can be employed without compromising the quality of salivary cortisol data. © 2005 Wiley Periodicals, Inc. Dev Psychobiol 47: 369–376, 2005.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Nicole M. Talge</name><affiliations><json:string>Institute of Child Development, University of Minnesota, Minneapolis, MN</json:string></affiliations></json:item><json:item><name>Bonny Donzella</name><affiliations><json:string>Institute of Child Development, University of Minnesota, Minneapolis, MN</json:string></affiliations></json:item><json:item><name>Erin M. Kryzer</name><affiliations><json:string>Institute of Child Development, University of Minnesota, Minneapolis, MN</json:string></affiliations></json:item><json:item><name>Andrea Gierens</name><affiliations><json:string>Department of Psychobiology, Universiteat of Trier, Germany</json:string></affiliations></json:item><json:item><name>Megan R. Gunnar</name><affiliations><json:string>Institute of Child Development, University of Minnesota, Minneapolis, MN</json:string><json:string>Institute of Child Development, University of Minnesota, Minneapolis, MN</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>salivary cortisol</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>children</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>methods</value></json:item></subject><articleId><json:string>DEV20097</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Evidence that oral stimulants can produce interference effects in salivary cortisol assays has led to advice to avoid their use. However, in studies with young children, the use of these saliva‐producing substances increases compliance with collection procedures. Four experiments are described to examine the effects of two commonly used stimulants, SweetTarts™ and Koolaid™. Across these experiments, interference effects produced by different quantities of these stimulants (0.025, 0.1, and 0.2 g) and those produced in two commonly used assays, DELFIA and EIA, were explored. The impact of using cotton rolls soaked with an oral stimulant prior to saliva collection was also examined. In general, oral stimulants did not affect the rank ordering of cortisol values, as the results for stimulant‐treated samples were highly correlated with those of untreated samples (approximately .90 for serially collected samples and .95 for aliquots of the same saliva pool). Depending on which assay was used, however, oral stimulants increased or decreased the cortisol levels reported, with effects sizes in the small to medium range. Thus, oral stimulants should not be used with only a portion of the subjects in a study, nor should researchers assay stimulant‐treated samples from the same study using different assays. When used sparingly, oral stimulants can be employed without compromising the quality of salivary cortisol data. © 2005 Wiley Periodicals, Inc. Dev Psychobiol 47: 369–376, 2005.</abstract><qualityIndicators><score>7.081</score><pdfVersion>1.3</pdfVersion><pdfPageSize>562 x 759 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>1494</abstractCharCount><pdfWordCount>4393</pdfWordCount><pdfCharCount>26609</pdfCharCount><pdfPageCount>8</pdfPageCount><abstractWordCount>224</abstractWordCount></qualityIndicators><title>It's not that bad: Error introduced by oral stimulants in salivary cortisol research</title><refBibs><json:item><host><author></author><title>Cohen, J.(1988).Statistical power analysis for the behavioral sciences,2nd ed.Hillsdale, NJ:Lawrence Erlbaum Associates.</title></host></json:item><json:item><author><json:item><name>M. R. 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However, in studies with young children, the use of these saliva‐producing substances increases compliance with collection procedures. Four experiments are described to examine the effects of two commonly used stimulants, SweetTarts™ and Koolaid™. Across these experiments, interference effects produced by different quantities of these stimulants (0.025, 0.1, and 0.2 g) and those produced in two commonly used assays, DELFIA and EIA, were explored. The impact of using cotton rolls soaked with an oral stimulant prior to saliva collection was also examined. In general, oral stimulants did not affect the rank ordering of cortisol values, as the results for stimulant‐treated samples were highly correlated with those of untreated samples (approximately .90 for serially collected samples and .95 for aliquots of the same saliva pool). Depending on which assay was used, however, oral stimulants increased or decreased the cortisol levels reported, with effects sizes in the small to medium range. Thus, oral stimulants should not be used with only a portion of the subjects in a study, nor should researchers assay stimulant‐treated samples from the same study using different assays. When used sparingly, oral stimulants can be employed without compromising the quality of salivary cortisol data. © 2005 Wiley Periodicals, Inc. 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However, in studies with young children, the use of these saliva‐producing substances increases compliance with collection procedures. Four experiments are described to examine the effects of two commonly used stimulants, SweetTarts™ and Koolaid™. Across these experiments, interference effects produced by different quantities of these stimulants (0.025, 0.1, and 0.2 g) and those produced in two commonly used assays, DELFIA and EIA, were explored. The impact of using cotton rolls soaked with an oral stimulant prior to saliva collection was also examined. In general, oral stimulants did not affect the rank ordering of cortisol values, as the results for stimulant‐treated samples were highly correlated with those of untreated samples (approximately .90 for serially collected samples and .95 for aliquots of the same saliva pool). Depending on which assay was used, however, oral stimulants increased or decreased the cortisol levels reported, with effects sizes in the small to medium range. Thus, oral stimulants should not be used with only a portion of the subjects in a study, nor should researchers assay stimulant‐treated samples from the same study using different assays. When used sparingly, oral stimulants can be employed without compromising the quality of salivary cortisol data. © 2005 Wiley Periodicals, Inc. <i>Dev Psychobiol</i> 47: 369–376, 2005.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>It's not that bad: Error introduced by oral stimulants in salivary cortisol research</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Stimulants in Salivary Cortisol Research</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>It's not that bad: Error introduced by oral stimulants in salivary cortisol research</title></titleInfo><name type="personal"><namePart type="given">Nicole M.</namePart><namePart type="family">Talge</namePart><affiliation>Institute of Child Development, University of Minnesota, Minneapolis, MN</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Bonny</namePart><namePart type="family">Donzella</namePart><affiliation>Institute of Child Development, University of Minnesota, Minneapolis, MN</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Erin M.</namePart><namePart type="family">Kryzer</namePart><affiliation>Institute of Child Development, University of Minnesota, Minneapolis, MN</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Andrea</namePart><namePart type="family">Gierens</namePart><affiliation>Department of Psychobiology, Universiteat of Trier, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Megan R.</namePart><namePart type="family">Gunnar</namePart><affiliation>Institute of Child Development, University of Minnesota, Minneapolis, MN</affiliation><affiliation>Institute of Child Development, University of Minnesota, Minneapolis, MN</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2005-12</dateIssued><dateCaptured encoding="w3cdtf">2004-11-15</dateCaptured><dateValid encoding="w3cdtf">2005-06-04</dateValid><copyrightDate encoding="w3cdtf">2005</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">2</extent><extent unit="tables">1</extent><extent unit="references">10</extent><extent unit="words">588</extent></physicalDescription><abstract lang="en">Evidence that oral stimulants can produce interference effects in salivary cortisol assays has led to advice to avoid their use. However, in studies with young children, the use of these saliva‐producing substances increases compliance with collection procedures. Four experiments are described to examine the effects of two commonly used stimulants, SweetTarts™ and Koolaid™. Across these experiments, interference effects produced by different quantities of these stimulants (0.025, 0.1, and 0.2 g) and those produced in two commonly used assays, DELFIA and EIA, were explored. The impact of using cotton rolls soaked with an oral stimulant prior to saliva collection was also examined. In general, oral stimulants did not affect the rank ordering of cortisol values, as the results for stimulant‐treated samples were highly correlated with those of untreated samples (approximately .90 for serially collected samples and .95 for aliquots of the same saliva pool). Depending on which assay was used, however, oral stimulants increased or decreased the cortisol levels reported, with effects sizes in the small to medium range. Thus, oral stimulants should not be used with only a portion of the subjects in a study, nor should researchers assay stimulant‐treated samples from the same study using different assays. When used sparingly, oral stimulants can be employed without compromising the quality of salivary cortisol data. © 2005 Wiley Periodicals, Inc. Dev Psychobiol 47: 369–376, 2005.</abstract><note type="funding">National Institute of Mental Health - No. MH65046; </note><note type="funding">Senior Scientist Award - No. MH066208; </note><note type="funding">National Service Research Award - No. MH15755; </note><subject lang="en"><genre>keywords</genre><topic>salivary cortisol</topic><topic>children</topic><topic>methods</topic></subject><relatedItem type="host"><titleInfo><title>Developmental Psychobiology</title></titleInfo><titleInfo type="abbreviated"><title>Dev. Psychobiol.</title></titleInfo><genre type="journal">journal</genre><identifier type="ISSN">0012-1630</identifier><identifier type="eISSN">1098-2302</identifier><identifier type="DOI">10.1002/(ISSN)1098-2302</identifier><identifier type="PublisherID">DEV</identifier><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>47</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>369</start><end>376</end><total>8</total></extent></part></relatedItem><identifier type="istex">AC04EE88EEADD252E1BE683DE5FDCAF95E36298C</identifier><identifier type="DOI">10.1002/dev.20097</identifier><identifier type="ArticleID">DEV20097</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2005 Wiley‐Liss, Inc.</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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