Effect of chloride on nitrite-induced methaemoglobinemia in Atlantic sturgeon, Acipenser oxyrinchus oxyrinchus (Mitchill).
Identifieur interne : 000444 ( Ncbi/Merge ); précédent : 000443; suivant : 000445Effect of chloride on nitrite-induced methaemoglobinemia in Atlantic sturgeon, Acipenser oxyrinchus oxyrinchus (Mitchill).
Auteurs : M A Matsche [États-Unis] ; E. Markin ; E. Donaldson ; A. Hengst ; A. LazurSource :
- Journal of fish diseases [ 1365-2761 ] ; 2012.
English descriptors
- KwdEn :
- Animals, Behavior, Animal, Blood (drug effects), Blood Cell Count, Blood Chemical Analysis, Chlorides (pharmacology), Chlorides (therapeutic use), Fish Diseases (chemically induced), Fish Diseases (drug therapy), Fish Diseases (mortality), Fishes, Gills (cytology), Gills (drug effects), Methemoglobin (analysis), Methemoglobinemia (chemically induced), Methemoglobinemia (drug therapy), Methemoglobinemia (mortality), Methemoglobinemia (veterinary), Nitrites (analysis), Nitrites (metabolism), Nitrites (toxicity), Water (chemistry), Water Quality.
- MESH :
- chemical , analysis : Methemoglobin, Nitrites.
- chemical , chemistry : Water.
- chemical , metabolism : Nitrites.
- chemical , pharmacology : Chlorides.
- chemically induced : Fish Diseases, Methemoglobinemia.
- cytology : Gills.
- drug effects : Blood, Gills.
- drug therapy : Fish Diseases, Methemoglobinemia.
- mortality : Fish Diseases, Methemoglobinemia.
- chemical , therapeutic use : Chlorides.
- chemical , toxicity : Nitrites.
- veterinary : Methemoglobinemia.
- Animals, Behavior, Animal, Blood Cell Count, Blood Chemical Analysis, Fishes, Water Quality.
Abstract
We evaluated the effects of chloride concentration on the clinical pathology in juvenile Atlantic sturgeon, Acipenser oxyrinchus oxyrinchus (Mitchill), following semi-static exposures to 1 mg L(-1) nitrite for 96 h. In spring water naturally low in chloride (5 mg L(-1)), plasma nitrite concentrated to more than 40× environmental levels resulting in a severe methaemoglobinemia characterized by torpid behaviour, 30-fold increase in methaemoglobin fraction, anaemia, leucopenia and hyperkalaemia. Loss of intracellular water and potassium to extracellular space may have resulted in hyperkalaemia and haemodilution. Fish survived nitrite exposure, but 60% of torpid fish died following capture and tissue sampling. Fish acclimated to 10-fold higher chloride content (55 mg L(-1)) did not concentrate nitrite in the plasma above environmental levels or develop methaemoglobinemia, but did exhibit similar haematology and plasma chemistry changes. Plasma nitrite returned to preexposure levels by 14 days following nitrite exposures, but severity of clinical pathology changes persisted or increased, suggesting that Atlantic sturgeon have reduced capacity to recover from methaemoglobinemia. Fish that survive methaemoglobinemia may be susceptible to mortality from the cumulative effects of intoxication, handling and other stresses for two or more weeks following nitrite remediation. Chloride buffering in aquaculture systems reduces the toxic effects of nitrite accumulation.
DOI: 10.1111/j.1365-2761.2012.01418.x
PubMed: 22973973
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Markin</name></author><author><name sortKey="Donaldson, E" sort="Donaldson, E" uniqKey="Donaldson E" first="E" last="Donaldson">E. Donaldson</name></author><author><name sortKey="Hengst, A" sort="Hengst, A" uniqKey="Hengst A" first="A" last="Hengst">A. Hengst</name></author><author><name sortKey="Lazur, A" sort="Lazur, A" uniqKey="Lazur A" first="A" last="Lazur">A. Lazur</name></author></analytic><series><title level="j">Journal of fish diseases</title><idno type="eISSN">1365-2761</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Behavior, Animal</term><term>Blood (drug effects)</term><term>Blood Cell Count</term><term>Blood Chemical Analysis</term><term>Chlorides (pharmacology)</term><term>Chlorides (therapeutic use)</term><term>Fish Diseases (chemically induced)</term><term>Fish Diseases (drug therapy)</term><term>Fish Diseases (mortality)</term><term>Fishes</term><term>Gills (cytology)</term><term>Gills (drug effects)</term><term>Methemoglobin (analysis)</term><term>Methemoglobinemia (chemically induced)</term><term>Methemoglobinemia (drug therapy)</term><term>Methemoglobinemia (mortality)</term><term>Methemoglobinemia (veterinary)</term><term>Nitrites (analysis)</term><term>Nitrites (metabolism)</term><term>Nitrites (toxicity)</term><term>Water (chemistry)</term><term>Water Quality</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Methemoglobin</term><term>Nitrites</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Water</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Nitrites</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Chlorides</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Fish Diseases</term><term>Methemoglobinemia</term></keywords><keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Gills</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Blood</term><term>Gills</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Fish Diseases</term><term>Methemoglobinemia</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Fish Diseases</term><term>Methemoglobinemia</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Chlorides</term></keywords><keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Nitrites</term></keywords><keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Methemoglobinemia</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Behavior, Animal</term><term>Blood Cell Count</term><term>Blood Chemical Analysis</term><term>Fishes</term><term>Water Quality</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We evaluated the effects of chloride concentration on the clinical pathology in juvenile Atlantic sturgeon, Acipenser oxyrinchus oxyrinchus (Mitchill), following semi-static exposures to 1 mg L(-1) nitrite for 96 h. In spring water naturally low in chloride (5 mg L(-1)), plasma nitrite concentrated to more than 40× environmental levels resulting in a severe methaemoglobinemia characterized by torpid behaviour, 30-fold increase in methaemoglobin fraction, anaemia, leucopenia and hyperkalaemia. Loss of intracellular water and potassium to extracellular space may have resulted in hyperkalaemia and haemodilution. Fish survived nitrite exposure, but 60% of torpid fish died following capture and tissue sampling. Fish acclimated to 10-fold higher chloride content (55 mg L(-1)) did not concentrate nitrite in the plasma above environmental levels or develop methaemoglobinemia, but did exhibit similar haematology and plasma chemistry changes. Plasma nitrite returned to preexposure levels by 14 days following nitrite exposures, but severity of clinical pathology changes persisted or increased, suggesting that Atlantic sturgeon have reduced capacity to recover from methaemoglobinemia. Fish that survive methaemoglobinemia may be susceptible to mortality from the cumulative effects of intoxication, handling and other stresses for two or more weeks following nitrite remediation. Chloride buffering in aquaculture systems reduces the toxic effects of nitrite accumulation.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22973973</PMID><DateCreated><Year>2012</Year><Month>11</Month><Day>06</Day></DateCreated><DateCompleted><Year>2013</Year><Month>02</Month><Day>01</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1365-2761</ISSN><JournalIssue CitedMedium="Internet"><Volume>35</Volume><Issue>12</Issue><PubDate><Year>2012</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Journal of fish diseases</Title><ISOAbbreviation>J. 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Fish survived nitrite exposure, but 60% of torpid fish died following capture and tissue sampling. Fish acclimated to 10-fold higher chloride content (55 mg L(-1)) did not concentrate nitrite in the plasma above environmental levels or develop methaemoglobinemia, but did exhibit similar haematology and plasma chemistry changes. Plasma nitrite returned to preexposure levels by 14 days following nitrite exposures, but severity of clinical pathology changes persisted or increased, suggesting that Atlantic sturgeon have reduced capacity to recover from methaemoglobinemia. Fish that survive methaemoglobinemia may be susceptible to mortality from the cumulative effects of intoxication, handling and other stresses for two or more weeks following nitrite remediation. Chloride buffering in aquaculture systems reduces the toxic effects of nitrite accumulation.</AbstractText><CopyrightInformation>© 2012 Blackwell Publishing Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Matsche</LastName><ForeName>M A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Cooperative Oxford Laboratory, Oxford, MD, USA. mmatsche@dnr.state.md.us</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Markin</LastName><ForeName>E</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Donaldson</LastName><ForeName>E</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Hengst</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Lazur</LastName><ForeName>A</ForeName><Initials>A</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013486">Research Support, U.S. Gov't, Non-P.H.S.</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2012</Year><Month>09</Month><Day>13</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Fish Dis</MedlineTA><NlmUniqueID>9881188</NlmUniqueID><ISSNLinking>0140-7775</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D002712">Chlorides</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D009573">Nitrites</NameOfSubstance></Chemical><Chemical><RegistryNumber>059QF0KO0R</RegistryNumber><NameOfSubstance UI="D014867">Water</NameOfSubstance></Chemical><Chemical><RegistryNumber>9008-37-1</RegistryNumber><NameOfSubstance 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UI="D005393" MajorTopicYN="N">Fish Diseases</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005399" MajorTopicYN="N">Fishes</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005880" MajorTopicYN="N">Gills</DescriptorName><QualifierName UI="Q000166" MajorTopicYN="N">cytology</QualifierName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008706" MajorTopicYN="N">Methemoglobin</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008708" MajorTopicYN="N">Methemoglobinemia</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="N">chemically induced</QualifierName><QualifierName UI="Q000188" 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PubStatus="revised"><Year>2012</Year><Month>01</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2012</Year><Month>01</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2012</Year><Month>9</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2012</Year><Month>9</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2013</Year><Month>2</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">22973973</ArticleId><ArticleId IdType="doi">10.1111/j.1365-2761.2012.01418.x</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Maryland</li></region></list><tree><noCountry><name sortKey="Donaldson, E" sort="Donaldson, E" uniqKey="Donaldson E" first="E" last="Donaldson">E. Donaldson</name><name sortKey="Hengst, A" sort="Hengst, A" uniqKey="Hengst A" first="A" last="Hengst">A. Hengst</name><name sortKey="Lazur, A" sort="Lazur, A" uniqKey="Lazur A" first="A" last="Lazur">A. Lazur</name><name sortKey="Markin, E" sort="Markin, E" uniqKey="Markin E" first="E" last="Markin">E. Markin</name></noCountry><country name="États-Unis"><region name="Maryland"><name sortKey="Matsche, M A" sort="Matsche, M A" uniqKey="Matsche M" first="M A" last="Matsche">M A Matsche</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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