[Analysis of creatine kinase variation in some members of the family Acipenseridae].
Identifieur interne : 000259 ( Ncbi/Curation ); précédent : 000258; suivant : 000260[Analysis of creatine kinase variation in some members of the family Acipenseridae].
Auteurs : E V Kuz'MinSource :
- Genetika [ 0016-6758 ] ; 2008.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : Creatine Kinase, Isoenzymes.
- chemical , metabolism : Creatine Kinase, Isoenzymes.
- genetics : Fishes.
- metabolism : Fishes, Muscle, Skeletal, Muscles.
- Animals, Organ Specificity, Polymorphism, Genetic.
Abstract
Creatine kinase (E.C. 2.7.3.2) was examined in stellate sturgeon Acipenser stellatus Pallas, Russian sturgeon A. gueldenstaedtii Brandt, European sterlet A. ruthenus L., Siberian sterlet A. ruthenus marsiglii Brandt, and great sturgeon (beluga) Huso huso L., using polyacrylamide gel electrophoresis. Two loci for creatine kinase were identified: CK-A* in white skeletal muscle and CK-C* in stomach wall muscle. Most species proved to be monomorphic at the CK-A* locus, showing the same phenotype represented by a single band. Heterogeneity and polymorphism in creatine kinase, determined by the CK-A* locus, were found only in Russian sturgeon. Based on the results of densitometric analysis of band staining intensity, we have advanced a hypothesis that synthesis of subunits of the CK-A* product in this species was controlled by eight genes. However, the genotype frequencies in the sample were significantly different from those theoretically expected upon free and independent gene recombination. The results of this study support the hypothesis on the absence of heterodimeric creatine kinase molecules in the skeletal muscle of Russian sturgeon. Locus CK-C* in sterlet was revealed as a single, intensely stained, rapidly migrating fraction, whereas in Russian sturgeon, the enzyme activity in this zone was very weak. No creatine kinase was found in liver, kidneys, spleen, heart, and intestine mucous tunic.
PubMed: 18666555
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000468
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000468
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000468
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000259
Links to Exploration step
pubmed:18666555Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Analysis of creatine kinase variation in some members of the family Acipenseridae].</title>
<author><name sortKey="Kuz Min, E V" sort="Kuz Min, E V" uniqKey="Kuz Min E" first="E V" last="Kuz'Min">E V Kuz'Min</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2008">2008</date>
<idno type="RBID">pubmed:18666555</idno>
<idno type="pmid">18666555</idno>
<idno type="wicri:Area/PubMed/Corpus">000468</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000468</idno>
<idno type="wicri:Area/PubMed/Curation">000468</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000468</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000468</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000468</idno>
<idno type="wicri:Area/Ncbi/Merge">000259</idno>
<idno type="wicri:Area/Ncbi/Curation">000259</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">[Analysis of creatine kinase variation in some members of the family Acipenseridae].</title>
<author><name sortKey="Kuz Min, E V" sort="Kuz Min, E V" uniqKey="Kuz Min E" first="E V" last="Kuz'Min">E V Kuz'Min</name>
</author>
</analytic>
<series><title level="j">Genetika</title>
<idno type="ISSN">0016-6758</idno>
<imprint><date when="2008" type="published">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Creatine Kinase (genetics)</term>
<term>Creatine Kinase (metabolism)</term>
<term>Fishes (genetics)</term>
<term>Fishes (metabolism)</term>
<term>Isoenzymes (genetics)</term>
<term>Isoenzymes (metabolism)</term>
<term>Muscle, Skeletal (metabolism)</term>
<term>Muscles (metabolism)</term>
<term>Organ Specificity</term>
<term>Polymorphism, Genetic</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Creatine Kinase</term>
<term>Isoenzymes</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Creatine Kinase</term>
<term>Isoenzymes</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Fishes</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Fishes</term>
<term>Muscle, Skeletal</term>
<term>Muscles</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Organ Specificity</term>
<term>Polymorphism, Genetic</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Creatine kinase (E.C. 2.7.3.2) was examined in stellate sturgeon Acipenser stellatus Pallas, Russian sturgeon A. gueldenstaedtii Brandt, European sterlet A. ruthenus L., Siberian sterlet A. ruthenus marsiglii Brandt, and great sturgeon (beluga) Huso huso L., using polyacrylamide gel electrophoresis. Two loci for creatine kinase were identified: CK-A* in white skeletal muscle and CK-C* in stomach wall muscle. Most species proved to be monomorphic at the CK-A* locus, showing the same phenotype represented by a single band. Heterogeneity and polymorphism in creatine kinase, determined by the CK-A* locus, were found only in Russian sturgeon. Based on the results of densitometric analysis of band staining intensity, we have advanced a hypothesis that synthesis of subunits of the CK-A* product in this species was controlled by eight genes. However, the genotype frequencies in the sample were significantly different from those theoretically expected upon free and independent gene recombination. The results of this study support the hypothesis on the absence of heterodimeric creatine kinase molecules in the skeletal muscle of Russian sturgeon. Locus CK-C* in sterlet was revealed as a single, intensely stained, rapidly migrating fraction, whereas in Russian sturgeon, the enzyme activity in this zone was very weak. No creatine kinase was found in liver, kidneys, spleen, heart, and intestine mucous tunic.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Eau/explor/EsturgeonV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000259 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 000259 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Eau |area= EsturgeonV1 |flux= Ncbi |étape= Curation |type= RBID |clé= pubmed:18666555 |texte= [Analysis of creatine kinase variation in some members of the family Acipenseridae]. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:18666555" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a EsturgeonV1
![]() | This area was generated with Dilib version V0.6.27. | ![]() |