Ontogeny of the somatostatin variant [Pro2,Met13]somatostatin‐14 in the brain, pituitary, and sensory organs of the frog Rana esculenta
Identifieur interne : 000D33 ( Main/Merge ); précédent : 000D32; suivant : 000D34Ontogeny of the somatostatin variant [Pro2,Met13]somatostatin‐14 in the brain, pituitary, and sensory organs of the frog Rana esculenta
Auteurs : Mauro Vallarino [Italie] ; Federica Bruzzone [Italie, France] ; Maura Mathieu [Italie] ; Nicolas Chartrel [France] ; Didier Vieau [France] ; Monica Ciarlo [Italie] ; Alain Fournier [Canada] ; Hubert Vaudry [France]Source :
- Journal of Comparative Neurology [ 0021-9967 ] ; 2006-08-10.
English descriptors
Abstract
Two forms of somatostatin are expressed in the frog brain, i.e., somatostatin‐14 (SS1) and the [Pro2, Met13]somatostatin‐14 variant (SS2). We have previously described the ontogeny of SS1‐immunoreactive cells in the brain of Rana esculenta. In the present study, we have investigated the distribution of prepro‐SS2 (PSS2)‐expressing neurons in the brain of the same species during development by using antibodies directed against the N‐flanking region of SS2 (PSS254‐66). Immunoreactive perikarya first appeared in the ventral hypothalamus at stages IV–VII. Subsequently, positive neurons were seen in the nucleus of the diagonal band of Broca, the anterior preoptic area, the posterior tuberculum (stages VIII–XII), as well as the dorsal (stages XIII–XV) and medial (stages XIX–XX) periventricular preoptic nucleus. At metamorphic climax and in newly metamorphosed frogs, positive perikarya were found in the striatum and in the interpeduncular nucleus. PSS254‐66‐immunoreactive fibers were already widely distributed during the first stages of development, indicating that SS2 may act as a neuromodulator and/or neurotransmitter during ontogeny. The presence of PSS254‐66‐positive nerve fibers in olfactory structures suggests that, in tadpoles, SS2 may be involved in the processing of olfactory information. The occurrence of PSS254‐66‐like immunoreactivity in taste buds, and in the olfactory and vomeronasal organs indicates that SS2 may mediate the unconditioned and reinforcing properties of natural chemicals. Finally, the intenseexpression of PSS254‐66‐like immunoreactivity in melanotrope cells of the pituitary suggests that SS2 may diffuse toward the pars distalis to regulate the activity of adenohypophysial cells during tadpole development. J. Comp. Neurol. 497:717–733, 2006. © 2006 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/cne.20986
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001277
- to stream Istex, to step Curation: 001275
- to stream Istex, to step Checkpoint: 000647
Links to Exploration step
ISTEX:50F63E85472097FDB2E3C88B1E3069468F053ED2Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Ontogeny of the somatostatin variant [Pro2,Met13]somatostatin‐14 in the brain, pituitary, and sensory organs of the frog Rana esculenta</title><author><name sortKey="Vallarino, Mauro" sort="Vallarino, Mauro" uniqKey="Vallarino M" first="Mauro" last="Vallarino">Mauro Vallarino</name></author><author><name sortKey="Bruzzone, Federica" sort="Bruzzone, Federica" uniqKey="Bruzzone F" first="Federica" last="Bruzzone">Federica Bruzzone</name></author><author><name sortKey="Mathieu, Maura" sort="Mathieu, Maura" uniqKey="Mathieu M" first="Maura" last="Mathieu">Maura Mathieu</name></author><author><name sortKey="Chartrel, Nicolas" sort="Chartrel, Nicolas" uniqKey="Chartrel N" first="Nicolas" last="Chartrel">Nicolas Chartrel</name></author><author><name sortKey="Vieau, Didier" sort="Vieau, Didier" uniqKey="Vieau D" first="Didier" last="Vieau">Didier Vieau</name></author><author><name sortKey="Ciarlo, Monica" sort="Ciarlo, Monica" uniqKey="Ciarlo M" first="Monica" last="Ciarlo">Monica Ciarlo</name></author><author><name sortKey="Fournier, Alain" sort="Fournier, Alain" uniqKey="Fournier A" first="Alain" last="Fournier">Alain Fournier</name></author><author><name sortKey="Vaudry, Hubert" sort="Vaudry, Hubert" uniqKey="Vaudry H" first="Hubert" last="Vaudry">Hubert Vaudry</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:50F63E85472097FDB2E3C88B1E3069468F053ED2</idno><date when="2006" year="2006">2006</date><idno type="doi">10.1002/cne.20986</idno><idno type="url">https://api.istex.fr/document/50F63E85472097FDB2E3C88B1E3069468F053ED2/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001277</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001277</idno><idno type="wicri:Area/Istex/Curation">001275</idno><idno type="wicri:Area/Istex/Checkpoint">000647</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000647</idno><idno type="wicri:doubleKey">0021-9967:2006:Vallarino M:ontogeny:of:the</idno><idno type="wicri:Area/Main/Merge">000D33</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Ontogeny of the somatostatin variant [Pro2,Met13]somatostatin‐14 in the brain, pituitary, and sensory organs of the frog Rana esculenta</title><author><name sortKey="Vallarino, Mauro" sort="Vallarino, Mauro" uniqKey="Vallarino M" first="Mauro" last="Vallarino">Mauro Vallarino</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Biology, DIBISAA, University of Genova, 16132 Genova</wicri:regionArea><wicri:noRegion>16132 Genova</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Biology, DIBISAA, Section of Neuroendocrinology and Developmental Biology, Viale Benedetto XV, 5, 16126 Genova</wicri:regionArea><wicri:noRegion>16126 Genova</wicri:noRegion></affiliation></author><author><name sortKey="Bruzzone, Federica" sort="Bruzzone, Federica" uniqKey="Bruzzone F" first="Federica" last="Bruzzone">Federica Bruzzone</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Biology, DIBISAA, University of Genova, 16132 Genova</wicri:regionArea><wicri:noRegion>16132 Genova</wicri:noRegion></affiliation><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>European Institute for Peptide Research (IFRMP 23), Laboratory of Cellular and Molecular Neuroendocrinology, INSERM U 413, University of Rouen, 76821 Mont‐Saint‐Aignan</wicri:regionArea><placeName><region type="region" nuts="2">Région Normandie</region><region type="old region" nuts="2">Haute-Normandie</region><settlement type="city">Mont‐Saint‐Aignan</settlement></placeName></affiliation></author><author><name sortKey="Mathieu, Maura" sort="Mathieu, Maura" uniqKey="Mathieu M" first="Maura" last="Mathieu">Maura Mathieu</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Biology, DIBISAA, University of Genova, 16132 Genova</wicri:regionArea><wicri:noRegion>16132 Genova</wicri:noRegion></affiliation></author><author><name sortKey="Chartrel, Nicolas" sort="Chartrel, Nicolas" uniqKey="Chartrel N" first="Nicolas" last="Chartrel">Nicolas Chartrel</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>European Institute for Peptide Research (IFRMP 23), Laboratory of Cellular and Molecular Neuroendocrinology, INSERM U 413, University of Rouen, 76821 Mont‐Saint‐Aignan</wicri:regionArea><placeName><region type="region" nuts="2">Région Normandie</region><region type="old region" nuts="2">Haute-Normandie</region><settlement type="city">Mont‐Saint‐Aignan</settlement></placeName></affiliation></author><author><name sortKey="Vieau, Didier" sort="Vieau, Didier" uniqKey="Vieau D" first="Didier" last="Vieau">Didier Vieau</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Laboratory of Developmental Neuroendocrinology, University of Lille, 59655 Villeneuve d'Ascq</wicri:regionArea><placeName><region type="region" nuts="2">Hauts-de-France</region><region type="old region" nuts="2">Nord-Pas-de-Calais</region><settlement type="city">Villeneuve d'Ascq</settlement></placeName></affiliation></author><author><name sortKey="Ciarlo, Monica" sort="Ciarlo, Monica" uniqKey="Ciarlo M" first="Monica" last="Ciarlo">Monica Ciarlo</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Biology, DIBISAA, University of Genova, 16132 Genova</wicri:regionArea><wicri:noRegion>16132 Genova</wicri:noRegion></affiliation></author><author><name sortKey="Fournier, Alain" sort="Fournier, Alain" uniqKey="Fournier A" first="Alain" last="Fournier">Alain Fournier</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Institut National de la Recherche Scientifique‐Institut Armand Frappier, Université du Québec, Pointe‐Claire, Québec H9R 1G6</wicri:regionArea><wicri:noRegion>Québec H9R 1G6</wicri:noRegion></affiliation></author><author><name sortKey="Vaudry, Hubert" sort="Vaudry, Hubert" uniqKey="Vaudry H" first="Hubert" last="Vaudry">Hubert Vaudry</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>European Institute for Peptide Research (IFRMP 23), Laboratory of Cellular and Molecular Neuroendocrinology, INSERM U 413, University of Rouen, 76821 Mont‐Saint‐Aignan</wicri:regionArea><placeName><region type="region" nuts="2">Région Normandie</region><region type="old region" nuts="2">Haute-Normandie</region><settlement type="city">Mont‐Saint‐Aignan</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Comparative Neurology</title><title level="j" type="abbrev">J. Comp. Neurol.</title><idno type="ISSN">0021-9967</idno><idno type="eISSN">1096-9861</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2006-08-10">2006-08-10</date><biblScope unit="volume">497</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="717">717</biblScope><biblScope unit="page" to="733">733</biblScope></imprint><idno type="ISSN">0021-9967</idno></series><idno type="istex">50F63E85472097FDB2E3C88B1E3069468F053ED2</idno><idno type="DOI">10.1002/cne.20986</idno><idno type="ArticleID">CNE20986</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0021-9967</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>[Pro2,Met13]somatostatin‐14 precursor</term><term>brain</term><term>development</term><term>frog</term><term>neuropeptides</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Two forms of somatostatin are expressed in the frog brain, i.e., somatostatin‐14 (SS1) and the [Pro2, Met13]somatostatin‐14 variant (SS2). We have previously described the ontogeny of SS1‐immunoreactive cells in the brain of Rana esculenta. In the present study, we have investigated the distribution of prepro‐SS2 (PSS2)‐expressing neurons in the brain of the same species during development by using antibodies directed against the N‐flanking region of SS2 (PSS254‐66). Immunoreactive perikarya first appeared in the ventral hypothalamus at stages IV–VII. Subsequently, positive neurons were seen in the nucleus of the diagonal band of Broca, the anterior preoptic area, the posterior tuberculum (stages VIII–XII), as well as the dorsal (stages XIII–XV) and medial (stages XIX–XX) periventricular preoptic nucleus. At metamorphic climax and in newly metamorphosed frogs, positive perikarya were found in the striatum and in the interpeduncular nucleus. PSS254‐66‐immunoreactive fibers were already widely distributed during the first stages of development, indicating that SS2 may act as a neuromodulator and/or neurotransmitter during ontogeny. The presence of PSS254‐66‐positive nerve fibers in olfactory structures suggests that, in tadpoles, SS2 may be involved in the processing of olfactory information. The occurrence of PSS254‐66‐like immunoreactivity in taste buds, and in the olfactory and vomeronasal organs indicates that SS2 may mediate the unconditioned and reinforcing properties of natural chemicals. Finally, the intenseexpression of PSS254‐66‐like immunoreactivity in melanotrope cells of the pituitary suggests that SS2 may diffuse toward the pars distalis to regulate the activity of adenohypophysial cells during tadpole development. J. Comp. Neurol. 497:717–733, 2006. © 2006 Wiley‐Liss, Inc.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Eau/explor/EsturgeonV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D33 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 000D33 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Eau
|area= EsturgeonV1
|flux= Main
|étape= Merge
|type= RBID
|clé= ISTEX:50F63E85472097FDB2E3C88B1E3069468F053ED2
|texte= Ontogeny of the somatostatin variant [Pro2,Met13]somatostatin‐14 in the brain, pituitary, and sensory organs of the frog Rana esculenta
}}
| This area was generated with Dilib version V0.6.27. |  |