Altered distribution of lipid‐soluble antioxidant vitamins in juvenile sturgeon exposed to waterborne ethynylestradiol
Identifieur interne : 001236 ( Istex/Corpus ); précédent : 001235; suivant : 001237Altered distribution of lipid‐soluble antioxidant vitamins in juvenile sturgeon exposed to waterborne ethynylestradiol
Auteurs : Vincr P. Palace ; Robert E. Evans ; Kerry Wautier ; Christopher L. Baron ; Julieta Werner ; Jack F. Klaverkamp ; Karen A. Kidd ; Terry A. DickSource :
- Environmental Toxicology and Chemistry [ 0730-7268 ] ; 2001-10.
English descriptors
- KwdEn :
Abstract
Studies in mammals have shown that exposure to estrogenic compounds can affect lipid metabolism and plasma concentrations of lipid‐soluble vitamins. However, the potential for estrogenic contaminants to induce these effects in fish has not yet been examined. The ability of the estrogen analog ethynylestradiol (EE2) to alter concentrations of the lipid‐soluble vitamins A and E in plasma, liver, and kidney was investigated in juvenile lake sturgeon (430 ± 20 g). The EE2 was delivered to the sturgeon in the tank water at nominal concentrations of 0 (control), 15, 60, or 125 ng EE2/L for a period of 25 d. Concentrations of the egg yolk precursor, vitellogenin, increased dose dependently in plasma. Plasma vitamin E (tocopherol), A1 (retinol), and A2 (dehydroretinol) were elevated by the two highest EE2 treatments compared with the controls. Esterified storage forms of vitamin A were marginally lower in the livers of fish from the highest EE2 dose group, but vitamin E levels in the liver were not significantly affected. Concentrations of vitamin E and vitamin A were significantly depleted in the kidney of fish from the two highest EE2 dose groups. Total lipid content was elevated in the gonad of fish treated with the highest dose of EE2 compared with the controls. Altered lipid and vitamin distribution may be induced by estrogen to facilitate gonadal maturation in sturgeon. Results from these studies indicate that an examination of the implications for vitamin depletion by estrogenic contaminants in juvenile fish is warranted.
Url:
DOI: 10.1002/etc.5620201032
Links to Exploration step
ISTEX:1EC3825E66C878568296D1C94BDC9BE851B42423Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Altered distribution of lipid‐soluble antioxidant vitamins in juvenile sturgeon exposed to waterborne ethynylestradiol</title><author><name sortKey="Palace, Vincr P" sort="Palace, Vincr P" uniqKey="Palace V" first="Vincr P." last="Palace">Vincr P. Palace</name><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation><affiliation><mods:affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation></author><author><name sortKey="Evans, Robert E" sort="Evans, Robert E" uniqKey="Evans R" first="Robert E." last="Evans">Robert E. Evans</name><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation></author><author><name sortKey="Wautier, Kerry" sort="Wautier, Kerry" uniqKey="Wautier K" first="Kerry" last="Wautier">Kerry Wautier</name><affiliation><mods:affiliation>Biotech West Consulting, Winnipeg R3V 1M4, Canada</mods:affiliation></affiliation></author><author><name sortKey="Baron, Christopher L" sort="Baron, Christopher L" uniqKey="Baron C" first="Christopher L." last="Baron">Christopher L. Baron</name><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation></author><author><name sortKey="Werner, Julieta" sort="Werner, Julieta" uniqKey="Werner J" first="Julieta" last="Werner">Julieta Werner</name><affiliation><mods:affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</mods:affiliation></affiliation></author><author><name sortKey="Klaverkamp, Jack F" sort="Klaverkamp, Jack F" uniqKey="Klaverkamp J" first="Jack F." last="Klaverkamp">Jack F. Klaverkamp</name><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation><affiliation><mods:affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</mods:affiliation></affiliation></author><author><name sortKey="Kidd, Karen A" sort="Kidd, Karen A" uniqKey="Kidd K" first="Karen A." last="Kidd">Karen A. Kidd</name><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation><affiliation><mods:affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</mods:affiliation></affiliation></author><author><name sortKey="Dick, Terry A" sort="Dick, Terry A" uniqKey="Dick T" first="Terry A." last="Dick">Terry A. Dick</name><affiliation><mods:affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:1EC3825E66C878568296D1C94BDC9BE851B42423</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1002/etc.5620201032</idno><idno type="url">https://api.istex.fr/document/1EC3825E66C878568296D1C94BDC9BE851B42423/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001236</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001236</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Altered distribution of lipid‐soluble antioxidant vitamins in juvenile sturgeon exposed to waterborne ethynylestradiol</title><author><name sortKey="Palace, Vincr P" sort="Palace, Vincr P" uniqKey="Palace V" first="Vincr P." last="Palace">Vincr P. Palace</name><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation><affiliation><mods:affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation></author><author><name sortKey="Evans, Robert E" sort="Evans, Robert E" uniqKey="Evans R" first="Robert E." last="Evans">Robert E. Evans</name><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation></author><author><name sortKey="Wautier, Kerry" sort="Wautier, Kerry" uniqKey="Wautier K" first="Kerry" last="Wautier">Kerry Wautier</name><affiliation><mods:affiliation>Biotech West Consulting, Winnipeg R3V 1M4, Canada</mods:affiliation></affiliation></author><author><name sortKey="Baron, Christopher L" sort="Baron, Christopher L" uniqKey="Baron C" first="Christopher L." last="Baron">Christopher L. Baron</name><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation></author><author><name sortKey="Werner, Julieta" sort="Werner, Julieta" uniqKey="Werner J" first="Julieta" last="Werner">Julieta Werner</name><affiliation><mods:affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</mods:affiliation></affiliation></author><author><name sortKey="Klaverkamp, Jack F" sort="Klaverkamp, Jack F" uniqKey="Klaverkamp J" first="Jack F." last="Klaverkamp">Jack F. Klaverkamp</name><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation><affiliation><mods:affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</mods:affiliation></affiliation></author><author><name sortKey="Kidd, Karen A" sort="Kidd, Karen A" uniqKey="Kidd K" first="Karen A." last="Kidd">Karen A. Kidd</name><affiliation><mods:affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</mods:affiliation></affiliation><affiliation><mods:affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</mods:affiliation></affiliation></author><author><name sortKey="Dick, Terry A" sort="Dick, Terry A" uniqKey="Dick T" first="Terry A." last="Dick">Terry A. Dick</name><affiliation><mods:affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Environmental Toxicology and Chemistry</title><title level="j" type="sub">An International Journal</title><title level="j" type="abbrev">Environmental Toxicology and Chemistry</title><idno type="ISSN">0730-7268</idno><idno type="eISSN">1552-8618</idno><imprint><publisher>Wiley Periodicals, Inc.</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2001-10">2001-10</date><biblScope unit="volume">20</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="2370">2370</biblScope><biblScope unit="page" to="2376">2376</biblScope></imprint><idno type="ISSN">0730-7268</idno></series><idno type="istex">1EC3825E66C878568296D1C94BDC9BE851B42423</idno><idno type="DOI">10.1002/etc.5620201032</idno><idno type="ArticleID">ETC5620201032</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0730-7268</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Ethynylestradiol</term><term>Lipids</term><term>Sturgeon</term><term>Vitamins</term><term>Vitellogenin</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Studies in mammals have shown that exposure to estrogenic compounds can affect lipid metabolism and plasma concentrations of lipid‐soluble vitamins. However, the potential for estrogenic contaminants to induce these effects in fish has not yet been examined. The ability of the estrogen analog ethynylestradiol (EE2) to alter concentrations of the lipid‐soluble vitamins A and E in plasma, liver, and kidney was investigated in juvenile lake sturgeon (430 ± 20 g). The EE2 was delivered to the sturgeon in the tank water at nominal concentrations of 0 (control), 15, 60, or 125 ng EE2/L for a period of 25 d. Concentrations of the egg yolk precursor, vitellogenin, increased dose dependently in plasma. Plasma vitamin E (tocopherol), A1 (retinol), and A2 (dehydroretinol) were elevated by the two highest EE2 treatments compared with the controls. Esterified storage forms of vitamin A were marginally lower in the livers of fish from the highest EE2 dose group, but vitamin E levels in the liver were not significantly affected. Concentrations of vitamin E and vitamin A were significantly depleted in the kidney of fish from the two highest EE2 dose groups. Total lipid content was elevated in the gonad of fish treated with the highest dose of EE2 compared with the controls. Altered lipid and vitamin distribution may be induced by estrogen to facilitate gonadal maturation in sturgeon. Results from these studies indicate that an examination of the implications for vitamin depletion by estrogenic contaminants in juvenile fish is warranted.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Vincr P. Palace</name><affiliations><json:string>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</json:string><json:string>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</json:string><json:string>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</json:string></affiliations></json:item><json:item><name>Robert E. Evans</name><affiliations><json:string>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</json:string></affiliations></json:item><json:item><name>Kerry Wautier</name><affiliations><json:string>Biotech West Consulting, Winnipeg R3V 1M4, Canada</json:string></affiliations></json:item><json:item><name>Christopher L. Baron</name><affiliations><json:string>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</json:string></affiliations></json:item><json:item><name>Julieta Werner</name><affiliations><json:string>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</json:string></affiliations></json:item><json:item><name>Jack F. Klaverkamp</name><affiliations><json:string>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</json:string><json:string>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</json:string></affiliations></json:item><json:item><name>Karen A. Kidd</name><affiliations><json:string>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</json:string><json:string>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</json:string></affiliations></json:item><json:item><name>Terry A. Dick</name><affiliations><json:string>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Ethynylestradiol</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Vitamins</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Sturgeon</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Lipids</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Vitellogenin</value></json:item></subject><articleId><json:string>ETC5620201032</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Studies in mammals have shown that exposure to estrogenic compounds can affect lipid metabolism and plasma concentrations of lipid‐soluble vitamins. However, the potential for estrogenic contaminants to induce these effects in fish has not yet been examined. The ability of the estrogen analog ethynylestradiol (EE2) to alter concentrations of the lipid‐soluble vitamins A and E in plasma, liver, and kidney was investigated in juvenile lake sturgeon (430 ± 20 g). The EE2 was delivered to the sturgeon in the tank water at nominal concentrations of 0 (control), 15, 60, or 125 ng EE2/L for a period of 25 d. Concentrations of the egg yolk precursor, vitellogenin, increased dose dependently in plasma. Plasma vitamin E (tocopherol), A1 (retinol), and A2 (dehydroretinol) were elevated by the two highest EE2 treatments compared with the controls. Esterified storage forms of vitamin A were marginally lower in the livers of fish from the highest EE2 dose group, but vitamin E levels in the liver were not significantly affected. Concentrations of vitamin E and vitamin A were significantly depleted in the kidney of fish from the two highest EE2 dose groups. Total lipid content was elevated in the gonad of fish treated with the highest dose of EE2 compared with the controls. Altered lipid and vitamin distribution may be induced by estrogen to facilitate gonadal maturation in sturgeon. Results from these studies indicate that an examination of the implications for vitamin depletion by estrogenic contaminants in juvenile fish is warranted.</abstract><qualityIndicators><score>7.928</score><pdfVersion>1.3</pdfVersion><pdfPageSize>576 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>1546</abstractCharCount><pdfWordCount>5324</pdfWordCount><pdfCharCount>33285</pdfCharCount><pdfPageCount>7</pdfPageCount><abstractWordCount>244</abstractWordCount></qualityIndicators><title>Altered distribution of lipid‐soluble antioxidant vitamins in juvenile sturgeon exposed to waterborne ethynylestradiol</title><genre><json:string>article</json:string></genre><host><volume>20</volume><publisherId><json:string>ETC</json:string></publisherId><pages><total>7</total><last>2376</last><first>2370</first></pages><issn><json:string>0730-7268</json:string></issn><issue>10</issue><subject><json:item><value>Environmental Toxicology</value></json:item></subject><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1552-8618</json:string></eissn><title>Environmental Toxicology and Chemistry</title><doi><json:string>10.1002/(ISSN)1552-8618</json:string></doi></host><categories><wos><json:string>science</json:string><json:string>toxicology</json:string><json:string>environmental sciences</json:string></wos><scienceMetrix><json:string>natural sciences</json:string><json:string>earth & environmental sciences</json:string><json:string>environmental sciences</json:string></scienceMetrix></categories><publicationDate>2001</publicationDate><copyrightDate>2001</copyrightDate><doi><json:string>10.1002/etc.5620201032</json:string></doi><id>1EC3825E66C878568296D1C94BDC9BE851B42423</id><score>0.03142438</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/1EC3825E66C878568296D1C94BDC9BE851B42423/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/1EC3825E66C878568296D1C94BDC9BE851B42423/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/1EC3825E66C878568296D1C94BDC9BE851B42423/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Altered distribution of lipid‐soluble antioxidant vitamins in juvenile sturgeon exposed to waterborne ethynylestradiol</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Periodicals, Inc.</publisher><pubPlace>Hoboken</pubPlace><availability><p>Copyright © 2001 SETAC</p></availability><date>2001</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Altered distribution of lipid‐soluble antioxidant vitamins in juvenile sturgeon exposed to waterborne ethynylestradiol</title><author xml:id="author-1"><persName><forename type="first">Vincr P.</forename><surname>Palace</surname></persName><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation><affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</affiliation><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation></author><author xml:id="author-2"><persName><forename type="first">Robert E.</forename><surname>Evans</surname></persName><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation></author><author xml:id="author-3"><persName><forename type="first">Kerry</forename><surname>Wautier</surname></persName><affiliation>Biotech West Consulting, Winnipeg R3V 1M4, Canada</affiliation></author><author xml:id="author-4"><persName><forename type="first">Christopher L.</forename><surname>Baron</surname></persName><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation></author><author xml:id="author-5"><persName><forename type="first">Julieta</forename><surname>Werner</surname></persName><affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</affiliation></author><author xml:id="author-6"><persName><forename type="first">Jack F.</forename><surname>Klaverkamp</surname></persName><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation><affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</affiliation></author><author xml:id="author-7"><persName><forename type="first">Karen A.</forename><surname>Kidd</surname></persName><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation><affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</affiliation></author><author xml:id="author-8"><persName><forename type="first">Terry A.</forename><surname>Dick</surname></persName><affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</affiliation></author></analytic><monogr><title level="j">Environmental Toxicology and Chemistry</title><title level="j" type="sub">An International Journal</title><title level="j" type="abbrev">Environmental Toxicology and Chemistry</title><idno type="pISSN">0730-7268</idno><idno type="eISSN">1552-8618</idno><idno type="DOI">10.1002/(ISSN)1552-8618</idno><imprint><publisher>Wiley Periodicals, Inc.</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2001-10"></date><biblScope unit="volume">20</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="2370">2370</biblScope><biblScope unit="page" to="2376">2376</biblScope></imprint></monogr><idno type="istex">1EC3825E66C878568296D1C94BDC9BE851B42423</idno><idno type="DOI">10.1002/etc.5620201032</idno><idno type="ArticleID">ETC5620201032</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2001</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Studies in mammals have shown that exposure to estrogenic compounds can affect lipid metabolism and plasma concentrations of lipid‐soluble vitamins. However, the potential for estrogenic contaminants to induce these effects in fish has not yet been examined. The ability of the estrogen analog ethynylestradiol (EE2) to alter concentrations of the lipid‐soluble vitamins A and E in plasma, liver, and kidney was investigated in juvenile lake sturgeon (430 ± 20 g). The EE2 was delivered to the sturgeon in the tank water at nominal concentrations of 0 (control), 15, 60, or 125 ng EE2/L for a period of 25 d. Concentrations of the egg yolk precursor, vitellogenin, increased dose dependently in plasma. Plasma vitamin E (tocopherol), A1 (retinol), and A2 (dehydroretinol) were elevated by the two highest EE2 treatments compared with the controls. Esterified storage forms of vitamin A were marginally lower in the livers of fish from the highest EE2 dose group, but vitamin E levels in the liver were not significantly affected. Concentrations of vitamin E and vitamin A were significantly depleted in the kidney of fish from the two highest EE2 dose groups. Total lipid content was elevated in the gonad of fish treated with the highest dose of EE2 compared with the controls. Altered lipid and vitamin distribution may be induced by estrogen to facilitate gonadal maturation in sturgeon. Results from these studies indicate that an examination of the implications for vitamin depletion by estrogenic contaminants in juvenile fish is warranted.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>keywords</head><item><term>Ethynylestradiol</term></item><item><term>Vitamins</term></item><item><term>Sturgeon</term></item><item><term>Lipids</term></item><item><term>Vitellogenin</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>article-category</head><item><term>Environmental Toxicology</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2000-10-20">Received</change><change when="2001-03-14">Registration</change><change when="2001-10">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/1EC3825E66C878568296D1C94BDC9BE851B42423/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Periodicals, Inc.</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1552-8618</doi><issn type="print">0730-7268</issn><issn type="electronic">1552-8618</issn><idGroup><id type="product" value="ETC"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY">Environmental Toxicology and Chemistry</title><title type="subtitle">An International Journal</title><title type="short">Environmental Toxicology and Chemistry</title></titleGroup></publicationMeta><publicationMeta level="part" position="100"><doi origin="wiley" registered="no">10.1002/etc.v20:10</doi><numberingGroup><numbering type="journalVolume" number="20">20</numbering><numbering type="journalIssue">10</numbering></numberingGroup><coverDate startDate="2001-10">October 2001</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="32" status="forIssue"><doi origin="wiley" registered="no">10.1002/etc.5620201032</doi><idGroup><id type="unit" value="ETC5620201032"></id></idGroup><countGroup><count type="pageTotal" number="7"></count></countGroup><titleGroup><title type="articleCategory">Environmental Toxicology</title><title type="tocHeading1">Environmental Toxicology</title></titleGroup><copyright ownership="thirdParty">Copyright © 2001 SETAC</copyright><eventGroup><event type="manuscriptReceived" date="2000-10-20"></event><event type="manuscriptAccepted" date="2001-03-14"></event><event type="firstOnline" date="2009-11-03"></event><event type="publishedOnlineFinalForm" date="2009-11-03"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.2 mode:FullText source:FullText result:FullText" date="2010-03-15"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-25"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-16"></event></eventGroup><numberingGroup><numbering type="pageFirst">2370</numbering><numbering type="pageLast">2376</numbering></numberingGroup><correspondenceTo>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:ETC.ETC5620201032.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="6"></count><count type="tableTotal" number="1"></count><count type="referenceTotal" number="48"></count></countGroup><titleGroup><title type="main" xml:lang="en">Altered distribution of lipid‐soluble antioxidant vitamins in juvenile sturgeon exposed to waterborne ethynylestradiol</title><title type="short" xml:lang="en">Lipid‐soluble vitamins in ethynylestradiol‐exposed sturgeon</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1 #af2" corresponding="yes"><personName><givenNames>Vincr P.</givenNames><familyName>Palace</familyName></personName><contactDetails><email normalForm="palacev@dfo-mpo.gc.ca">palacev@dfo‐mpo.gc.ca</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Robert E.</givenNames><familyName>Evans</familyName></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Kerry</givenNames><familyName>Wautier</familyName></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Christopher L.</givenNames><familyName>Baron</familyName></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Julieta</givenNames><familyName>Werner</familyName></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af1 #af2"><personName><givenNames>Jack F.</givenNames><familyName>Klaverkamp</familyName></personName></creator><creator xml:id="au7" creatorRole="author" affiliationRef="#af1 #af2"><personName><givenNames>Karen A.</givenNames><familyName>Kidd</familyName></personName></creator><creator xml:id="au8" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Terry A.</givenNames><familyName>Dick</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="CA" type="organization"><unparsedAffiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="CA" type="organization"><unparsedAffiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="CA" type="organization"><unparsedAffiliation>Biotech West Consulting, Winnipeg R3V 1M4, Canada</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">Ethynylestradiol</keyword><keyword xml:id="kwd2">Vitamins</keyword><keyword xml:id="kwd3">Sturgeon</keyword><keyword xml:id="kwd4">Lipids</keyword><keyword xml:id="kwd5">Vitellogenin</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Studies in mammals have shown that exposure to estrogenic compounds can affect lipid metabolism and plasma concentrations of lipid‐soluble vitamins. However, the potential for estrogenic contaminants to induce these effects in fish has not yet been examined. The ability of the estrogen analog ethynylestradiol (EE2) to alter concentrations of the lipid‐soluble vitamins A and E in plasma, liver, and kidney was investigated in juvenile lake sturgeon (430 ± 20 g). The EE2 was delivered to the sturgeon in the tank water at nominal concentrations of 0 (control), 15, 60, or 125 ng EE2/L for a period of 25 d. Concentrations of the egg yolk precursor, vitellogenin, increased dose dependently in plasma. Plasma vitamin E (tocopherol), A1 (retinol), and A2 (dehydroretinol) were elevated by the two highest EE2 treatments compared with the controls. Esterified storage forms of vitamin A were marginally lower in the livers of fish from the highest EE2 dose group, but vitamin E levels in the liver were not significantly affected. Concentrations of vitamin E and vitamin A were significantly depleted in the kidney of fish from the two highest EE2 dose groups. Total lipid content was elevated in the gonad of fish treated with the highest dose of EE2 compared with the controls. Altered lipid and vitamin distribution may be induced by estrogen to facilitate gonadal maturation in sturgeon. Results from these studies indicate that an examination of the implications for vitamin depletion by estrogenic contaminants in juvenile fish is warranted.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Altered distribution of lipid‐soluble antioxidant vitamins in juvenile sturgeon exposed to waterborne ethynylestradiol</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Lipid‐soluble vitamins in ethynylestradiol‐exposed sturgeon</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Altered distribution of lipid‐soluble antioxidant vitamins in juvenile sturgeon exposed to waterborne ethynylestradiol</title></titleInfo><name type="personal"><namePart type="given">Vincr P.</namePart><namePart type="family">Palace</namePart><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation><affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</affiliation><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Robert E.</namePart><namePart type="family">Evans</namePart><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kerry</namePart><namePart type="family">Wautier</namePart><affiliation>Biotech West Consulting, Winnipeg R3V 1M4, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Christopher L.</namePart><namePart type="family">Baron</namePart><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Julieta</namePart><namePart type="family">Werner</namePart><affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jack F.</namePart><namePart type="family">Klaverkamp</namePart><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation><affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Karen A.</namePart><namePart type="family">Kidd</namePart><affiliation>Department of Fisheries and Oceans, Central and Arctic Region, Winnipeg R3T 2N6, Canada</affiliation><affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Terry A.</namePart><namePart type="family">Dick</namePart><affiliation>University of Manitoba, Department of Zoology, Winnipeg R3T 2N2, Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Periodicals, Inc.</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2001-10</dateIssued><dateCaptured encoding="w3cdtf">2000-10-20</dateCaptured><dateValid encoding="w3cdtf">2001-03-14</dateValid><copyrightDate encoding="w3cdtf">2001</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">6</extent><extent unit="tables">1</extent><extent unit="references">48</extent></physicalDescription><abstract lang="en">Studies in mammals have shown that exposure to estrogenic compounds can affect lipid metabolism and plasma concentrations of lipid‐soluble vitamins. However, the potential for estrogenic contaminants to induce these effects in fish has not yet been examined. The ability of the estrogen analog ethynylestradiol (EE2) to alter concentrations of the lipid‐soluble vitamins A and E in plasma, liver, and kidney was investigated in juvenile lake sturgeon (430 ± 20 g). The EE2 was delivered to the sturgeon in the tank water at nominal concentrations of 0 (control), 15, 60, or 125 ng EE2/L for a period of 25 d. Concentrations of the egg yolk precursor, vitellogenin, increased dose dependently in plasma. Plasma vitamin E (tocopherol), A1 (retinol), and A2 (dehydroretinol) were elevated by the two highest EE2 treatments compared with the controls. Esterified storage forms of vitamin A were marginally lower in the livers of fish from the highest EE2 dose group, but vitamin E levels in the liver were not significantly affected. Concentrations of vitamin E and vitamin A were significantly depleted in the kidney of fish from the two highest EE2 dose groups. Total lipid content was elevated in the gonad of fish treated with the highest dose of EE2 compared with the controls. Altered lipid and vitamin distribution may be induced by estrogen to facilitate gonadal maturation in sturgeon. Results from these studies indicate that an examination of the implications for vitamin depletion by estrogenic contaminants in juvenile fish is warranted.</abstract><subject lang="en"><genre>keywords</genre><topic>Ethynylestradiol</topic><topic>Vitamins</topic><topic>Sturgeon</topic><topic>Lipids</topic><topic>Vitellogenin</topic></subject><relatedItem type="host"><titleInfo><title>Environmental Toxicology and Chemistry</title><subTitle>An International Journal</subTitle></titleInfo><titleInfo type="abbreviated"><title>Environmental Toxicology and Chemistry</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>Environmental Toxicology</topic></subject><identifier type="ISSN">0730-7268</identifier><identifier type="eISSN">1552-8618</identifier><identifier type="DOI">10.1002/(ISSN)1552-8618</identifier><identifier type="PublisherID">ETC</identifier><part><date>2001</date><detail type="volume"><caption>vol.</caption><number>20</number></detail><detail type="issue"><caption>no.</caption><number>10</number></detail><extent unit="pages"><start>2370</start><end>2376</end><total>7</total></extent></part></relatedItem><identifier type="istex">1EC3825E66C878568296D1C94BDC9BE851B42423</identifier><identifier type="DOI">10.1002/etc.5620201032</identifier><identifier type="ArticleID">ETC5620201032</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2001 SETAC</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Periodicals, Inc.</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Eau/explor/EsturgeonV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001236 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 001236 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Eau
|area= EsturgeonV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:1EC3825E66C878568296D1C94BDC9BE851B42423
|texte= Altered distribution of lipid‐soluble antioxidant vitamins in juvenile sturgeon exposed to waterborne ethynylestradiol
}}
| This area was generated with Dilib version V0.6.27. |  |