‘Fish matters’: the relevance of fish skin biology to investigative dermatology
Identifieur interne : 000718 ( Istex/Corpus ); précédent : 000717; suivant : 000719‘Fish matters’: the relevance of fish skin biology to investigative dermatology
Auteurs : Sebastian Rakers ; Marina Gebert ; Sai Uppalapati ; Wilfried Meyer ; Paul Maderson ; Anne F. Sell ; Charli Kruse ; Ralf PausSource :
- Experimental Dermatology [ 0906-6705 ] ; 2010-04.
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Abstract
Please cite this paper as:‘Fish matters’: the relevance of fish skin biology to investigative dermatology. Experimental Dermatology 2010.
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DOI: 10.1111/j.1600-0625.2009.01059.x
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ISTEX:B12F20BE8D0252C9B1FE189FD63474E4E161B6A2Le document en format XML
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Experimental Dermatology 2010.</p></abstract><abstract><p>Abstract: Fish skin is a multi‐purpose tissue that serves numerous vital functions including chemical and physical protection, sensory activity, behavioural purposes or hormone metabolism. Further, it is an important first‐line defense system against pathogens, as fish are continuously exposed to multiple microbial challenges in their aquatic habitat. Fish skin excels in highly developed antimicrobial features, many of which have been preserved throughout evolution, and infection defense principles employed by piscine skin are still operative in human skin. This review argues that it is both rewarding and important for investigative dermatologists to revive their interest in fish skin biology, as it provides insights into numerous fundamental issues that are of major relevance to mammalian skin. The basic molecular insights provided by zebrafish in vivo‐genomics for genetic, regeneration and melanoma research, the complex antimicrobial defense systems of fish skin and the molecular controls of melanocyte stem cells are just some of the fascinating examples that illustrate the multiple potential uses of fish skin models in investigative dermatology. We synthesize the essentials of fish skin biology and highlight selected aspects that are of particular comparative interest to basic and clinically applied human skin research.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>keywords</head><item><term>antimicrobial defense</term></item><item><term>epidermis</term></item><item><term>fish skin</term></item><item><term>fish stem cells</term></item><item><term>mucus</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2010-04">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/B12F20BE8D0252C9B1FE189FD63474E4E161B6A2/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" 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number="324">324</numbering></numberingGroup><correspondenceTo>Prof Dr Charli Kruse, Fraunhofer Research Institution for Marine Biotechnology, Paul‐Ehrlich‐Street 1‐3, 23562 Lübeck, Germany, Tel.: 0049‐451‐38444810, Fax: 0049‐451‐38444812, e‐mail: <email>charli.kruse@emb.fraunhofer.de</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:EXD.EXD1059.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Accepted for publication 07 December 2009</unparsedEditorialHistory><countGroup><count type="figureTotal" number="6"></count><count type="tableTotal" number="2"></count></countGroup><titleGroup><title type="main">‘Fish matters’: the relevance of fish skin biology to investigative dermatology</title><title type="shortAuthors">Rakers et al.</title><title type="short">Biology of fish skin</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" 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countryCode="DE"><unparsedAffiliation>Institute of Sea Fisheries, Johann Heinrich von Thünen‐Institute, Federal Research Institute for Rural Areas, Forestry and Fisheries, Hamburg, Germany;</unparsedAffiliation></affiliation><affiliation xml:id="a6" countryCode="GB"><unparsedAffiliation>Dermatological Sciences Group, School of Translational Medicine, University of Manchester, Manchester, UK</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">antimicrobial defense</keyword><keyword xml:id="k2">epidermis</keyword><keyword xml:id="k3">fish skin</keyword><keyword xml:id="k4">fish stem cells</keyword><keyword xml:id="k5">mucus</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><p> <i>Please cite this paper as:</i>‘Fish matters’: the relevance of fish skin biology to investigative dermatology. Experimental Dermatology 2010.</p><p><b>Abstract: </b> Fish skin is a multi‐purpose tissue that serves numerous vital functions including chemical and physical protection, sensory activity, behavioural purposes or hormone metabolism. Further, it is an important first‐line defense system against pathogens, as fish are continuously exposed to multiple microbial challenges in their aquatic habitat. Fish skin excels in highly developed antimicrobial features, many of which have been preserved throughout evolution, and infection defense principles employed by piscine skin are still operative in human skin. This review argues that it is both rewarding and important for investigative dermatologists to revive their interest in fish skin biology, as it provides insights into numerous fundamental issues that are of major relevance to mammalian skin. The basic molecular insights provided by zebrafish <i>in vivo</i>‐genomics for genetic, regeneration and melanoma research, the complex antimicrobial defense systems of fish skin and the molecular controls of melanocyte stem cells are just some of the fascinating examples that illustrate the multiple potential uses of fish skin models in investigative dermatology. We synthesize the essentials of fish skin biology and highlight selected aspects that are of particular comparative interest to basic and clinically applied human skin research.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>‘Fish matters’: the relevance of fish skin biology to investigative dermatology</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Biology of fish skin</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>‘Fish matters’: the relevance of fish skin biology to investigative dermatology</title></titleInfo><name type="personal"><namePart type="given">Sebastian</namePart><namePart type="family">Rakers</namePart><affiliation>LG Aquatic Celltechnology, Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany;</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Marina</namePart><namePart type="family">Gebert</namePart><affiliation>LG Aquatic Celltechnology, Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany;</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sai</namePart><namePart type="family">Uppalapati</namePart><affiliation>Department of Dermatology, University of Lübeck, Lübeck, Germany;</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Wilfried</namePart><namePart type="family">Meyer</namePart><affiliation>Institute for Anatomy, University of Veterinary Medicine, Hannover, Germany;</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Paul</namePart><namePart type="family">Maderson</namePart><affiliation>Brooklyn College of CUNY, Quakertown, PA, USA;</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Anne F.</namePart><namePart type="family">Sell</namePart><affiliation>Institute of Sea Fisheries, Johann Heinrich von Thünen‐Institute, Federal Research Institute for Rural Areas, Forestry and Fisheries, Hamburg, Germany;</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Charli</namePart><namePart type="family">Kruse</namePart><affiliation>LG Aquatic Celltechnology, Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany;</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ralf</namePart><namePart type="family">Paus</namePart><affiliation>Department of Dermatology, University of Lübeck, Lübeck, Germany;</affiliation><affiliation>Dermatological Sciences Group, School of Translational Medicine, University of Manchester, Manchester, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="review-article" displayLabel="reviewArticle"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2010-04</dateIssued><edition>Accepted for publication 07 December 2009</edition><copyrightDate encoding="w3cdtf">2010</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">6</extent><extent unit="tables">2</extent></physicalDescription><abstract>Please cite this paper as:‘Fish matters’: the relevance of fish skin biology to investigative dermatology. Experimental Dermatology 2010.</abstract><abstract>Abstract: Fish skin is a multi‐purpose tissue that serves numerous vital functions including chemical and physical protection, sensory activity, behavioural purposes or hormone metabolism. Further, it is an important first‐line defense system against pathogens, as fish are continuously exposed to multiple microbial challenges in their aquatic habitat. Fish skin excels in highly developed antimicrobial features, many of which have been preserved throughout evolution, and infection defense principles employed by piscine skin are still operative in human skin. This review argues that it is both rewarding and important for investigative dermatologists to revive their interest in fish skin biology, as it provides insights into numerous fundamental issues that are of major relevance to mammalian skin. The basic molecular insights provided by zebrafish in vivo‐genomics for genetic, regeneration and melanoma research, the complex antimicrobial defense systems of fish skin and the molecular controls of melanocyte stem cells are just some of the fascinating examples that illustrate the multiple potential uses of fish skin models in investigative dermatology. We synthesize the essentials of fish skin biology and highlight selected aspects that are of particular comparative interest to basic and clinically applied human skin research.</abstract><subject lang="en"><genre>keywords</genre><topic>antimicrobial defense</topic><topic>epidermis</topic><topic>fish skin</topic><topic>fish stem cells</topic><topic>mucus</topic></subject><relatedItem type="host"><titleInfo><title>Experimental Dermatology</title></titleInfo><genre type="journal">journal</genre><identifier type="ISSN">0906-6705</identifier><identifier type="eISSN">1600-0625</identifier><identifier type="DOI">10.1111/(ISSN)1600-0625</identifier><identifier type="PublisherID">EXD</identifier><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>313</start><end>324</end><total>12</total></extent></part></relatedItem><identifier type="istex">B12F20BE8D0252C9B1FE189FD63474E4E161B6A2</identifier><identifier type="DOI">10.1111/j.1600-0625.2009.01059.x</identifier><identifier type="ArticleID">EXD1059</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2010 John Wiley & Sons A/S</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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