Proteins with antifungal properties and other medicinal applications from plants and mushrooms.
Identifieur interne : 000292 ( Main/Corpus ); précédent : 000291; suivant : 000293Proteins with antifungal properties and other medicinal applications from plants and mushrooms.
Auteurs : Jack H. Wong ; T B Ng ; Randy C F. Cheung ; X J Ye ; H X Wang ; S K Lam ; P. Lin ; Y S Chan ; Evandro F. Fang ; Patrick H K. Ngai ; L X Xia ; X Y Ye ; Y. Jiang ; F. LiuSource :
- Applied microbiology and biotechnology [ 1432-0614 ] ; 2010.
English descriptors
- KwdEn :
- Agaricales (chemistry), Agaricales (genetics), Agaricales (metabolism), Animals (MeSH), Antifungal Agents (metabolism), Antifungal Agents (pharmacology), Antifungal Agents (therapeutic use), Drug Therapy (MeSH), Fungal Proteins (metabolism), Fungal Proteins (pharmacology), Fungal Proteins (therapeutic use), Fungi (drug effects), Humans (MeSH), Plant Proteins (metabolism), Plant Proteins (pharmacology), Plant Proteins (therapeutic use), Plants (genetics), Plants (metabolism), Plants (microbiology).
- MESH :
- chemical , metabolism : Antifungal Agents, Fungal Proteins, Plant Proteins.
- chemistry : Agaricales.
- drug effects : Fungi.
- genetics : Agaricales, Plants.
- metabolism : Agaricales, Plants.
- microbiology : Plants.
- chemical , pharmacology : Antifungal Agents, Fungal Proteins, Plant Proteins.
- chemical , therapeutic use : Antifungal Agents, Fungal Proteins, Plant Proteins.
- Animals, Drug Therapy, Humans.
Abstract
Living organisms produce a myriad of molecules to protect themselves from fungal pathogens. This review focuses on antifungal proteins from plants and mushrooms, many of which are components of the human diet or have medicinal value. Plant antifungal proteins can be classified into different groups comprising chitinases and chitinase-like proteins, chitin-binding proteins, cyclophilin-like proteins, defensins and defensin-like proteins, deoxyribonucleases, embryo-abundant protein-like proteins, glucanases, lectins, lipid transfer proteins, peroxidases, protease inhibitors, ribonucleases, ribosome-inactivating proteins, storage 2S albumins, and thaumatin-like proteins. Some of the aforementioned antifungal proteins also exhibit mitogenic activity towards spleen cells, nitric oxide inducing activity toward macrophages, antiproliferative activity toward tumor cells, antibacterial activity, and inhibitory activity toward HIV-1 reverse transcriptase. In contrast to the large diversity of plant antifungal proteins, only a small number of mushroom antifungal proteins have been reported. Mushroom antifungal proteins are distinct from their plant counterparts in N-terminal sequence. Nevertheless, some of the mushroom antifungal proteins have been shown to inhibit HIV-1 reverse transcriptase activity and tumor cell proliferation.
DOI: 10.1007/s00253-010-2690-4
PubMed: 20532758
Links to Exploration step
pubmed:20532758Le document en format XML
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Cheung</name></author><author><name sortKey="Ye, X J" sort="Ye, X J" uniqKey="Ye X" first="X J" last="Ye">X J Ye</name></author><author><name sortKey="Wang, H X" sort="Wang, H X" uniqKey="Wang H" first="H X" last="Wang">H X Wang</name></author><author><name sortKey="Lam, S K" sort="Lam, S K" uniqKey="Lam S" first="S K" last="Lam">S K Lam</name></author><author><name sortKey="Lin, P" sort="Lin, P" uniqKey="Lin P" first="P" last="Lin">P. Lin</name></author><author><name sortKey="Chan, Y S" sort="Chan, Y S" uniqKey="Chan Y" first="Y S" last="Chan">Y S Chan</name></author><author><name sortKey="Fang, Evandro F" sort="Fang, Evandro F" uniqKey="Fang E" first="Evandro F" last="Fang">Evandro F. Fang</name></author><author><name sortKey="Ngai, Patrick H K" sort="Ngai, Patrick H K" uniqKey="Ngai P" first="Patrick H K" last="Ngai">Patrick H K. Ngai</name></author><author><name sortKey="Xia, L X" sort="Xia, L X" uniqKey="Xia L" first="L X" last="Xia">L X Xia</name></author><author><name sortKey="Ye, X Y" sort="Ye, X Y" uniqKey="Ye X" first="X Y" last="Ye">X Y Ye</name></author><author><name sortKey="Jiang, Y" sort="Jiang, Y" uniqKey="Jiang Y" first="Y" last="Jiang">Y. Jiang</name></author><author><name sortKey="Liu, F" sort="Liu, F" uniqKey="Liu F" first="F" last="Liu">F. Liu</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="RBID">pubmed:20532758</idno><idno type="pmid">20532758</idno><idno type="doi">10.1007/s00253-010-2690-4</idno><idno type="wicri:Area/Main/Corpus">000292</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000292</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Proteins with antifungal properties and other medicinal applications from plants and mushrooms.</title><author><name sortKey="Wong, Jack H" sort="Wong, Jack H" uniqKey="Wong J" first="Jack H" last="Wong">Jack H. Wong</name><affiliation><nlm:affiliation>The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.</nlm:affiliation></affiliation></author><author><name sortKey="Ng, T B" sort="Ng, T B" uniqKey="Ng T" first="T B" last="Ng">T B Ng</name></author><author><name sortKey="Cheung, Randy C F" sort="Cheung, Randy C F" uniqKey="Cheung R" first="Randy C F" last="Cheung">Randy C F. Cheung</name></author><author><name sortKey="Ye, X J" sort="Ye, X J" uniqKey="Ye X" first="X J" last="Ye">X J Ye</name></author><author><name sortKey="Wang, H X" sort="Wang, H X" uniqKey="Wang H" first="H X" last="Wang">H X Wang</name></author><author><name sortKey="Lam, S K" sort="Lam, S K" uniqKey="Lam S" first="S K" last="Lam">S K Lam</name></author><author><name sortKey="Lin, P" sort="Lin, P" uniqKey="Lin P" first="P" last="Lin">P. Lin</name></author><author><name sortKey="Chan, Y S" sort="Chan, Y S" uniqKey="Chan Y" first="Y S" last="Chan">Y S Chan</name></author><author><name sortKey="Fang, Evandro F" sort="Fang, Evandro F" uniqKey="Fang E" first="Evandro F" last="Fang">Evandro F. Fang</name></author><author><name sortKey="Ngai, Patrick H K" sort="Ngai, Patrick H K" uniqKey="Ngai P" first="Patrick H K" last="Ngai">Patrick H K. Ngai</name></author><author><name sortKey="Xia, L X" sort="Xia, L X" uniqKey="Xia L" first="L X" last="Xia">L X Xia</name></author><author><name sortKey="Ye, X Y" sort="Ye, X Y" uniqKey="Ye X" first="X Y" last="Ye">X Y Ye</name></author><author><name sortKey="Jiang, Y" sort="Jiang, Y" uniqKey="Jiang Y" first="Y" last="Jiang">Y. Jiang</name></author><author><name sortKey="Liu, F" sort="Liu, F" uniqKey="Liu F" first="F" last="Liu">F. Liu</name></author></analytic><series><title level="j">Applied microbiology and biotechnology</title><idno type="eISSN">1432-0614</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Agaricales (chemistry)</term><term>Agaricales (genetics)</term><term>Agaricales (metabolism)</term><term>Animals (MeSH)</term><term>Antifungal Agents (metabolism)</term><term>Antifungal Agents (pharmacology)</term><term>Antifungal Agents (therapeutic use)</term><term>Drug Therapy (MeSH)</term><term>Fungal Proteins (metabolism)</term><term>Fungal Proteins (pharmacology)</term><term>Fungal Proteins (therapeutic use)</term><term>Fungi (drug effects)</term><term>Humans (MeSH)</term><term>Plant Proteins (metabolism)</term><term>Plant Proteins (pharmacology)</term><term>Plant Proteins (therapeutic use)</term><term>Plants (genetics)</term><term>Plants (metabolism)</term><term>Plants (microbiology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Antifungal Agents</term><term>Fungal Proteins</term><term>Plant Proteins</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Agaricales</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Fungi</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Agaricales</term><term>Plants</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Agaricales</term><term>Plants</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Plants</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antifungal Agents</term><term>Fungal Proteins</term><term>Plant Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antifungal Agents</term><term>Fungal Proteins</term><term>Plant Proteins</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Drug Therapy</term><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Living organisms produce a myriad of molecules to protect themselves from fungal pathogens. This review focuses on antifungal proteins from plants and mushrooms, many of which are components of the human diet or have medicinal value. Plant antifungal proteins can be classified into different groups comprising chitinases and chitinase-like proteins, chitin-binding proteins, cyclophilin-like proteins, defensins and defensin-like proteins, deoxyribonucleases, embryo-abundant protein-like proteins, glucanases, lectins, lipid transfer proteins, peroxidases, protease inhibitors, ribonucleases, ribosome-inactivating proteins, storage 2S albumins, and thaumatin-like proteins. Some of the aforementioned antifungal proteins also exhibit mitogenic activity towards spleen cells, nitric oxide inducing activity toward macrophages, antiproliferative activity toward tumor cells, antibacterial activity, and inhibitory activity toward HIV-1 reverse transcriptase. In contrast to the large diversity of plant antifungal proteins, only a small number of mushroom antifungal proteins have been reported. Mushroom antifungal proteins are distinct from their plant counterparts in N-terminal sequence. Nevertheless, some of the mushroom antifungal proteins have been shown to inhibit HIV-1 reverse transcriptase activity and tumor cell proliferation.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">20532758</PMID><DateCompleted><Year>2010</Year><Month>09</Month><Day>27</Day></DateCompleted><DateRevised><Year>2010</Year><Month>06</Month><Day>28</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1432-0614</ISSN><JournalIssue CitedMedium="Internet"><Volume>87</Volume><Issue>4</Issue><PubDate><Year>2010</Year><Month>Jul</Month></PubDate></JournalIssue><Title>Applied microbiology and biotechnology</Title><ISOAbbreviation>Appl Microbiol Biotechnol</ISOAbbreviation></Journal><ArticleTitle>Proteins with antifungal properties and other medicinal applications from plants and mushrooms.</ArticleTitle><Pagination><MedlinePgn>1221-35</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s00253-010-2690-4</ELocationID><Abstract><AbstractText>Living organisms produce a myriad of molecules to protect themselves from fungal pathogens. This review focuses on antifungal proteins from plants and mushrooms, many of which are components of the human diet or have medicinal value. Plant antifungal proteins can be classified into different groups comprising chitinases and chitinase-like proteins, chitin-binding proteins, cyclophilin-like proteins, defensins and defensin-like proteins, deoxyribonucleases, embryo-abundant protein-like proteins, glucanases, lectins, lipid transfer proteins, peroxidases, protease inhibitors, ribonucleases, ribosome-inactivating proteins, storage 2S albumins, and thaumatin-like proteins. Some of the aforementioned antifungal proteins also exhibit mitogenic activity towards spleen cells, nitric oxide inducing activity toward macrophages, antiproliferative activity toward tumor cells, antibacterial activity, and inhibitory activity toward HIV-1 reverse transcriptase. In contrast to the large diversity of plant antifungal proteins, only a small number of mushroom antifungal proteins have been reported. Mushroom antifungal proteins are distinct from their plant counterparts in N-terminal sequence. Nevertheless, some of the mushroom antifungal proteins have been shown to inhibit HIV-1 reverse transcriptase activity and tumor cell proliferation.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wong</LastName><ForeName>Jack H</ForeName><Initials>JH</Initials><AffiliationInfo><Affiliation>The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ng</LastName><ForeName>T B</ForeName><Initials>TB</Initials></Author><Author ValidYN="Y"><LastName>Cheung</LastName><ForeName>Randy C F</ForeName><Initials>RC</Initials></Author><Author ValidYN="Y"><LastName>Ye</LastName><ForeName>X J</ForeName><Initials>XJ</Initials></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>H X</ForeName><Initials>HX</Initials></Author><Author ValidYN="Y"><LastName>Lam</LastName><ForeName>S K</ForeName><Initials>SK</Initials></Author><Author ValidYN="Y"><LastName>Lin</LastName><ForeName>P</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Chan</LastName><ForeName>Y S</ForeName><Initials>YS</Initials></Author><Author ValidYN="Y"><LastName>Fang</LastName><ForeName>Evandro F</ForeName><Initials>EF</Initials></Author><Author ValidYN="Y"><LastName>Ngai</LastName><ForeName>Patrick H K</ForeName><Initials>PH</Initials></Author><Author ValidYN="Y"><LastName>Xia</LastName><ForeName>L X</ForeName><Initials>LX</Initials></Author><Author ValidYN="Y"><LastName>Ye</LastName><ForeName>X Y</ForeName><Initials>XY</Initials></Author><Author ValidYN="Y"><LastName>Jiang</LastName><ForeName>Y</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>F</ForeName><Initials>F</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2010</Year><Month>06</Month><Day>08</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Appl Microbiol Biotechnol</MedlineTA><NlmUniqueID>8406612</NlmUniqueID><ISSNLinking>0175-7598</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000935">Antifungal Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005656">Fungal Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010940">Plant Proteins</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000363" MajorTopicYN="N">Agaricales</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000935" MajorTopicYN="N">Antifungal Agents</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004358" MajorTopicYN="Y">Drug Therapy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005656" MajorTopicYN="N">Fungal Proteins</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005658" MajorTopicYN="N">Fungi</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010940" MajorTopicYN="N">Plant Proteins</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010944" MajorTopicYN="N">Plants</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading></MeshHeadingList><NumberOfReferences>140</NumberOfReferences></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2010</Year><Month>03</Month><Day>08</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2010</Year><Month>05</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2010</Year><Month>05</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2010</Year><Month>6</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2010</Year><Month>6</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2010</Year><Month>9</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">20532758</ArticleId><ArticleId IdType="doi">10.1007/s00253-010-2690-4</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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