The challenge of enzyme cost in the production of lignocellulosic biofuels.
Identifieur interne : 002C27 ( Main/Corpus ); précédent : 002C26; suivant : 002C28The challenge of enzyme cost in the production of lignocellulosic biofuels.
Auteurs : Daniel Klein-Marcuschamer ; Piotr Oleskowicz-Popiel ; Blake A. Simmons ; Harvey W. BlanchSource :
- Biotechnology and bioengineering [ 1097-0290 ] ; 2012.
English descriptors
- KwdEn :
- Batch Cell Culture Techniques (economics), Benchmarking (MeSH), Biofuels (economics), Capital Expenditures (MeSH), Carbohydrates (MeSH), Cellulase (economics), Costs and Cost Analysis (MeSH), Ethanol (economics), Ethanol (metabolism), Fermentation (MeSH), Fungal Proteins (economics), Lignin (economics), Lignin (metabolism), Models, Economic (MeSH), Populus (MeSH), Soybeans (economics), Trichoderma (enzymology), Wood (economics), Zea mays (economics).
- MESH :
- chemical , economics : Biofuels, Cellulase, Ethanol, Fungal Proteins, Lignin.
- economics : Batch Cell Culture Techniques, Soybeans, Wood, Zea mays.
- enzymology : Trichoderma.
- chemical , metabolism : Ethanol, Lignin.
- Benchmarking, Capital Expenditures, Carbohydrates, Costs and Cost Analysis, Fermentation, Models, Economic, Populus.
Abstract
With the aim of understanding the contribution of enzymes to the cost of lignocellulosic biofuels, we constructed a techno-economic model for the production of fungal cellulases. We found that the cost of producing enzymes was much higher than that commonly assumed in the literature. For example, the cost contribution of enzymes to ethanol produced by the conversion of corn stover was found to be $0.68/gal if the sugars in the biomass could be converted at maximum theoretical yields, and $1.47/gal if the yields were based on saccharification and fermentation yields that have been previously reported in the scientific literature. We performed a sensitivity analysis to study the effect of feedstock prices and fermentation times on the cost contribution of enzymes to ethanol price. We conclude that a significant effort is still required to lower the contribution of enzymes to biofuel production costs.
DOI: 10.1002/bit.24370
PubMed: 22095526
Links to Exploration step
pubmed:22095526Le document en format XML
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Simmons</name></author><author><name sortKey="Blanch, Harvey W" sort="Blanch, Harvey W" uniqKey="Blanch H" first="Harvey W" last="Blanch">Harvey W. 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We found that the cost of producing enzymes was much higher than that commonly assumed in the literature. For example, the cost contribution of enzymes to ethanol produced by the conversion of corn stover was found to be $0.68/gal if the sugars in the biomass could be converted at maximum theoretical yields, and $1.47/gal if the yields were based on saccharification and fermentation yields that have been previously reported in the scientific literature. We performed a sensitivity analysis to study the effect of feedstock prices and fermentation times on the cost contribution of enzymes to ethanol price. We conclude that a significant effort is still required to lower the contribution of enzymes to biofuel production costs.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22095526</PMID><DateCompleted><Year>2012</Year><Month>06</Month><Day>25</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1097-0290</ISSN><JournalIssue CitedMedium="Internet"><Volume>109</Volume><Issue>4</Issue><PubDate><Year>2012</Year><Month>Apr</Month></PubDate></JournalIssue><Title>Biotechnology and bioengineering</Title><ISOAbbreviation>Biotechnol Bioeng</ISOAbbreviation></Journal><ArticleTitle>The challenge of enzyme cost in the production of lignocellulosic biofuels.</ArticleTitle><Pagination><MedlinePgn>1083-7</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/bit.24370</ELocationID><Abstract><AbstractText>With the aim of understanding the contribution of enzymes to the cost of lignocellulosic biofuels, we constructed a techno-economic model for the production of fungal cellulases. We found that the cost of producing enzymes was much higher than that commonly assumed in the literature. For example, the cost contribution of enzymes to ethanol produced by the conversion of corn stover was found to be $0.68/gal if the sugars in the biomass could be converted at maximum theoretical yields, and $1.47/gal if the yields were based on saccharification and fermentation yields that have been previously reported in the scientific literature. We performed a sensitivity analysis to study the effect of feedstock prices and fermentation times on the cost contribution of enzymes to ethanol price. 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