[Comparative analysis of ergogenic efficacy of energy drinks components (caffeine and bitter orange extract) in combination with alcohol].
Identifieur interne : 000402 ( PubMed/Curation ); précédent : 000401; suivant : 000403[Comparative analysis of ergogenic efficacy of energy drinks components (caffeine and bitter orange extract) in combination with alcohol].
Auteurs : A M Anuchin ; G G IuvsSource :
- Voprosy pitaniia [ 0042-8833 ] ; 2014.
English descriptors
- KwdEn :
- Animals, Behavior, Animal (drug effects), Caffeine (pharmacology), Central Nervous System Depressants (pharmacology), Central Nervous System Stimulants (pharmacology), Citrus sinensis (chemistry), Energy Drinks, Ethanol (pharmacology), Male, Motor Activity (drug effects), Physical Endurance (drug effects), Plant Extracts (chemistry), Plant Extracts (pharmacology), Rats, Rats, Wistar.
- MESH :
- chemical , chemistry : Plant Extracts.
- chemical , pharmacology : Caffeine, Central Nervous System Depressants, Central Nervous System Stimulants, Ethanol, Plant Extracts.
- chemistry : Citrus sinensis.
- drug effects : Behavior, Animal, Motor Activity, Physical Endurance.
- Animals, Energy Drinks, Male, Rats, Rats, Wistar.
Abstract
Estimation of ergogenic effects of caffeine and bitter orange exract combined with alcohol is presented in the article. Investigations were performed on 3 groups (8 animals in each group) of male Wistar rats aged 4 months. Animals in group 1 were treated orally for 7 days, the mixture comprising caffeine and alcohol (0.6 g of caffeine, 72 ml of ethanol, water to 1 liter) in an amount equivalent to 4.28 mg caffeine per kg of body weight. Animals in group 2 received a mixture containing bitter orange extract and alcohol (1 g bitter orange extract, 72 ml of ethanol, water to 1 liter) in an amount equivalent to 0.43 mg of synephrine per kg body weight. Animals in the control group received the same volume (7.1 ml/kg) 7.2% aqueous solution of ethanol. Group of animals consumed caffeine in mixture with alcohol and the control group exhibited a significant weight gain, while the body weight of animals treated with the extract of bitter orange didn't significantly change. Using the methodology of the open field the effects of caffeine and bitter orange extract in combination with alcohol on the ratio of the active components of the orienting-exploratory behavior and passive-defensive behavior have been determined. Administration of mixture with caffeine increased locomotory activity by 164%, administration of bitter orange extract didn't affect this performance. Introduction of caffeine containing mixture significantly reduced the level of situational anxiety, which was manifested in the reduction of time spent by the animal in the center of the arena. The effects of ergogenic components on the performance of static and dynamic muscle endurance have been investigated. Single administration of the mixture containing caffeine, after 30 min caused a significant increase in performance and, consequently, endurance of glycolytic muscle fibers measured using the "inverted grid" test. Animals from this group produced 186% more work compared with control animals. Acute administration of bitter orange extract did not cause significant changes in static endurance. At the same time after 7 days of its daily administration a slight increase in dynamic endurance (test "treadmill") has been determined, which was expressed in some increase in the amount of work done by animals fed bitter orange extract compared with the control group of animals. Death of 1 animal in the group consumed bitter orange exract mixture with alcohol indicates potential risks of synephrine consumation together with alcohol.
PubMed: 25059058
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Comparative analysis of ergogenic efficacy of energy drinks components (caffeine and bitter orange extract) in combination with alcohol].</title><author><name sortKey="Anuchin, A M" sort="Anuchin, A M" uniqKey="Anuchin A" first="A M" last="Anuchin">A M Anuchin</name></author><author><name sortKey="Iuvs, G G" sort="Iuvs, G G" uniqKey="Iuvs G" first="G G" last="Iuvs">G G Iuvs</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:25059058</idno><idno type="pmid">25059058</idno><idno type="wicri:Area/PubMed/Corpus">000402</idno><idno type="wicri:Area/PubMed/Curation">000402</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Comparative analysis of ergogenic efficacy of energy drinks components (caffeine and bitter orange extract) in combination with alcohol].</title><author><name sortKey="Anuchin, A M" sort="Anuchin, A M" uniqKey="Anuchin A" first="A M" last="Anuchin">A M Anuchin</name></author><author><name sortKey="Iuvs, G G" sort="Iuvs, G G" uniqKey="Iuvs G" first="G G" last="Iuvs">G G Iuvs</name></author></analytic><series><title level="j">Voprosy pitaniia</title><idno type="ISSN">0042-8833</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Behavior, Animal (drug effects)</term><term>Caffeine (pharmacology)</term><term>Central Nervous System Depressants (pharmacology)</term><term>Central Nervous System Stimulants (pharmacology)</term><term>Citrus sinensis (chemistry)</term><term>Energy Drinks</term><term>Ethanol (pharmacology)</term><term>Male</term><term>Motor Activity (drug effects)</term><term>Physical Endurance (drug effects)</term><term>Plant Extracts (chemistry)</term><term>Plant Extracts (pharmacology)</term><term>Rats</term><term>Rats, Wistar</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Plant Extracts</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Caffeine</term><term>Central Nervous System Depressants</term><term>Central Nervous System Stimulants</term><term>Ethanol</term><term>Plant Extracts</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Citrus sinensis</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Behavior, Animal</term><term>Motor Activity</term><term>Physical Endurance</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Energy Drinks</term><term>Male</term><term>Rats</term><term>Rats, Wistar</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Estimation of ergogenic effects of caffeine and bitter orange exract combined with alcohol is presented in the article. Investigations were performed on 3 groups (8 animals in each group) of male Wistar rats aged 4 months. Animals in group 1 were treated orally for 7 days, the mixture comprising caffeine and alcohol (0.6 g of caffeine, 72 ml of ethanol, water to 1 liter) in an amount equivalent to 4.28 mg caffeine per kg of body weight. Animals in group 2 received a mixture containing bitter orange extract and alcohol (1 g bitter orange extract, 72 ml of ethanol, water to 1 liter) in an amount equivalent to 0.43 mg of synephrine per kg body weight. Animals in the control group received the same volume (7.1 ml/kg) 7.2% aqueous solution of ethanol. Group of animals consumed caffeine in mixture with alcohol and the control group exhibited a significant weight gain, while the body weight of animals treated with the extract of bitter orange didn't significantly change. Using the methodology of the open field the effects of caffeine and bitter orange extract in combination with alcohol on the ratio of the active components of the orienting-exploratory behavior and passive-defensive behavior have been determined. Administration of mixture with caffeine increased locomotory activity by 164%, administration of bitter orange extract didn't affect this performance. Introduction of caffeine containing mixture significantly reduced the level of situational anxiety, which was manifested in the reduction of time spent by the animal in the center of the arena. The effects of ergogenic components on the performance of static and dynamic muscle endurance have been investigated. Single administration of the mixture containing caffeine, after 30 min caused a significant increase in performance and, consequently, endurance of glycolytic muscle fibers measured using the "inverted grid" test. Animals from this group produced 186% more work compared with control animals. Acute administration of bitter orange extract did not cause significant changes in static endurance. At the same time after 7 days of its daily administration a slight increase in dynamic endurance (test "treadmill") has been determined, which was expressed in some increase in the amount of work done by animals fed bitter orange extract compared with the control group of animals. Death of 1 animal in the group consumed bitter orange exract mixture with alcohol indicates potential risks of synephrine consumation together with alcohol.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25059058</PMID><DateCreated><Year>2014</Year><Month>7</Month><Day>25</Day></DateCreated><DateCompleted><Year>2014</Year><Month>09</Month><Day>04</Day></DateCompleted><DateRevised><Year>2014</Year><Month>7</Month><Day>25</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0042-8833</ISSN><JournalIssue CitedMedium="Print"><Volume>83</Volume><Issue>1</Issue><PubDate><Year>2014</Year></PubDate></JournalIssue><Title>Voprosy pitaniia</Title><ISOAbbreviation>Vopr Pitan</ISOAbbreviation></Journal><ArticleTitle>[Comparative analysis of ergogenic efficacy of energy drinks components (caffeine and bitter orange extract) in combination with alcohol].</ArticleTitle><Pagination><MedlinePgn>61-6</MedlinePgn></Pagination><Abstract><AbstractText>Estimation of ergogenic effects of caffeine and bitter orange exract combined with alcohol is presented in the article. Investigations were performed on 3 groups (8 animals in each group) of male Wistar rats aged 4 months. Animals in group 1 were treated orally for 7 days, the mixture comprising caffeine and alcohol (0.6 g of caffeine, 72 ml of ethanol, water to 1 liter) in an amount equivalent to 4.28 mg caffeine per kg of body weight. Animals in group 2 received a mixture containing bitter orange extract and alcohol (1 g bitter orange extract, 72 ml of ethanol, water to 1 liter) in an amount equivalent to 0.43 mg of synephrine per kg body weight. Animals in the control group received the same volume (7.1 ml/kg) 7.2% aqueous solution of ethanol. Group of animals consumed caffeine in mixture with alcohol and the control group exhibited a significant weight gain, while the body weight of animals treated with the extract of bitter orange didn't significantly change. Using the methodology of the open field the effects of caffeine and bitter orange extract in combination with alcohol on the ratio of the active components of the orienting-exploratory behavior and passive-defensive behavior have been determined. Administration of mixture with caffeine increased locomotory activity by 164%, administration of bitter orange extract didn't affect this performance. Introduction of caffeine containing mixture significantly reduced the level of situational anxiety, which was manifested in the reduction of time spent by the animal in the center of the arena. The effects of ergogenic components on the performance of static and dynamic muscle endurance have been investigated. Single administration of the mixture containing caffeine, after 30 min caused a significant increase in performance and, consequently, endurance of glycolytic muscle fibers measured using the "inverted grid" test. Animals from this group produced 186% more work compared with control animals. Acute administration of bitter orange extract did not cause significant changes in static endurance. At the same time after 7 days of its daily administration a slight increase in dynamic endurance (test "treadmill") has been determined, which was expressed in some increase in the amount of work done by animals fed bitter orange extract compared with the control group of animals. Death of 1 animal in the group consumed bitter orange exract mixture with alcohol indicates potential risks of synephrine consumation together with alcohol.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Anuchin</LastName><ForeName>A M</ForeName><Initials>AM</Initials></Author><Author ValidYN="Y"><LastName>Iuvs</LastName><ForeName>G G</ForeName><Initials>GG</Initials></Author></AuthorList><Language>RUS</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Russia (Federation)</Country><MedlineTA>Vopr Pitan</MedlineTA><NlmUniqueID>2984870R</NlmUniqueID><ISSNLinking>0042-8833</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D002492">Central Nervous System Depressants</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000697">Central Nervous System Stimulants</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010936">Plant Extracts</NameOfSubstance></Chemical><Chemical><RegistryNumber>3G6A5W338E</RegistryNumber><NameOfSubstance UI="D002110">Caffeine</NameOfSubstance></Chemical><Chemical><RegistryNumber>3K9958V90M</RegistryNumber><NameOfSubstance UI="D000431">Ethanol</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001522" MajorTopicYN="N">Behavior, Animal</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002110" MajorTopicYN="N">Caffeine</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002492" MajorTopicYN="N">Central Nervous System Depressants</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000697" MajorTopicYN="N">Central Nervous System Stimulants</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D032084" MajorTopicYN="N">Citrus sinensis</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D061215" MajorTopicYN="Y">Energy Drinks</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000431" MajorTopicYN="N">Ethanol</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009043" MajorTopicYN="N">Motor Activity</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010807" MajorTopicYN="N">Physical Endurance</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010936" MajorTopicYN="N">Plant Extracts</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D051381" MajorTopicYN="N">Rats</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017208" MajorTopicYN="N">Rats, Wistar</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>7</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>7</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>9</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">25059058</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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