The Prospective Role of Plant Products in Radiotherapy of Cancer: A Current Overview
Identifieur interne : 001176 ( Main/Exploration ); précédent : 001175; suivant : 001177The Prospective Role of Plant Products in Radiotherapy of Cancer: A Current Overview
Auteurs : Banasri Hazra [Inde] ; Subhalakshmi Ghosh [Inde] ; Amit Kumar [Inde] ; B. N. Pandey [Inde]Source :
- Frontiers in Pharmacology [ 1663-9812 ] ; 2012.
Abstract
Treatment of cancer often requires exposure to radiation, which has several limitations involving non-specific toxicity toward normal cells, reducing the efficacy of treatment. Efforts are going on to find chemical compounds which would effectively offer protection to the normal tissues after radiation exposure during radiotherapy of cancer. In this regard, plant-derived compounds might serve as “leads” to design ideal radioprotectors/radiosensitizers. This article reviews some of the recent findings on prospective medicinal plants, phytochemicals, and their analogs, based on both
Url:
DOI: 10.3389/fphar.2011.00094
PubMed: 22291649
PubMed Central: 3253585
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Prospective Role of Plant Products in Radiotherapy of Cancer: A Current Overview</title><author><name sortKey="Hazra, Banasri" sort="Hazra, Banasri" uniqKey="Hazra B" first="Banasri" last="Hazra">Banasri Hazra</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Pharmaceutical Technology, Jadavpur University</institution><country>Kolkata, India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea></wicri:regionArea></affiliation></author><author><name sortKey="Ghosh, Subhalakshmi" sort="Ghosh, Subhalakshmi" uniqKey="Ghosh S" first="Subhalakshmi" last="Ghosh">Subhalakshmi Ghosh</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Pharmaceutical Technology, Jadavpur University</institution><country>Kolkata, India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea></wicri:regionArea></affiliation></author><author><name sortKey="Kumar, Amit" sort="Kumar, Amit" uniqKey="Kumar A" first="Amit" last="Kumar">Amit Kumar</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre</institution><country>Mumbai, India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea></wicri:regionArea></affiliation></author><author><name sortKey="Pandey, B N" sort="Pandey, B N" uniqKey="Pandey B" first="B. N." last="Pandey">B. N. Pandey</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre</institution><country>Mumbai, India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea></wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22291649</idno><idno type="pmc">3253585</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253585</idno><idno type="RBID">PMC:3253585</idno><idno type="doi">10.3389/fphar.2011.00094</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">001368</idno><idno type="wicri:Area/Pmc/Curation">001366</idno><idno type="wicri:Area/Pmc/Checkpoint">000C05</idno><idno type="wicri:Area/Ncbi/Merge">000E97</idno><idno type="wicri:Area/Ncbi/Curation">000E97</idno><idno type="wicri:Area/Ncbi/Checkpoint">000E97</idno><idno type="wicri:Area/Main/Merge">001188</idno><idno type="wicri:Area/Main/Curation">001176</idno><idno type="wicri:Area/Main/Exploration">001176</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Prospective Role of Plant Products in Radiotherapy of Cancer: A Current Overview</title><author><name sortKey="Hazra, Banasri" sort="Hazra, Banasri" uniqKey="Hazra B" first="Banasri" last="Hazra">Banasri Hazra</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Pharmaceutical Technology, Jadavpur University</institution><country>Kolkata, India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea></wicri:regionArea></affiliation></author><author><name sortKey="Ghosh, Subhalakshmi" sort="Ghosh, Subhalakshmi" uniqKey="Ghosh S" first="Subhalakshmi" last="Ghosh">Subhalakshmi Ghosh</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Pharmaceutical Technology, Jadavpur University</institution><country>Kolkata, India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea></wicri:regionArea></affiliation></author><author><name sortKey="Kumar, Amit" sort="Kumar, Amit" uniqKey="Kumar A" first="Amit" last="Kumar">Amit Kumar</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre</institution><country>Mumbai, India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea></wicri:regionArea></affiliation></author><author><name sortKey="Pandey, B N" sort="Pandey, B N" uniqKey="Pandey B" first="B. N." last="Pandey">B. N. Pandey</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre</institution><country>Mumbai, India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea></wicri:regionArea></affiliation></author></analytic><series><title level="j">Frontiers in Pharmacology</title><idno type="eISSN">1663-9812</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Treatment of cancer often requires exposure to radiation, which has several limitations involving non-specific toxicity toward normal cells, reducing the efficacy of treatment. Efforts are going on to find chemical compounds which would effectively offer protection to the normal tissues after radiation exposure during radiotherapy of cancer. In this regard, plant-derived compounds might serve as “leads” to design ideal radioprotectors/radiosensitizers. This article reviews some of the recent findings on prospective medicinal plants, phytochemicals, and their analogs, based on both <italic>in vitro</italic> and <italic>in vivo</italic> tumor models especially focused with relevance to cancer radiotherapy. Also, pertinent discussion has been presented on the molecular mechanism of apoptotic death in relation to the oxidative stress in cancer cells induced by some of these plant samples and their active constituents.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Adaramoye, O A" uniqKey="Adaramoye O">O. A. Adaramoye</name></author><author><name sortKey="Adedara, I A" uniqKey="Adedara I">I. A. Adedara</name></author><author><name sortKey="Popoola, B" uniqKey="Popoola B">B. Popoola</name></author><author><name sortKey="Farombi, E O" uniqKey="Farombi E">E. O. 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Liu</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Inde</li></country></list><tree><country name="Inde"><noRegion><name sortKey="Hazra, Banasri" sort="Hazra, Banasri" uniqKey="Hazra B" first="Banasri" last="Hazra">Banasri Hazra</name></noRegion><name sortKey="Ghosh, Subhalakshmi" sort="Ghosh, Subhalakshmi" uniqKey="Ghosh S" first="Subhalakshmi" last="Ghosh">Subhalakshmi Ghosh</name><name sortKey="Kumar, Amit" sort="Kumar, Amit" uniqKey="Kumar A" first="Amit" last="Kumar">Amit Kumar</name><name sortKey="Pandey, B N" sort="Pandey, B N" uniqKey="Pandey B" first="B. N." last="Pandey">B. N. Pandey</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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