Iron-citrate complexes and free radicals generation: is citric acid an innocent additive in foods and drinks?
Identifieur interne : 002292 ( Main/Exploration ); précédent : 002291; suivant : 002293Iron-citrate complexes and free radicals generation: is citric acid an innocent additive in foods and drinks?
Auteurs : Isabelle Gautier-Luneau [France] ; Perrine Bertet ; André Jeunet ; Guy Serratrice ; Jean-Louis PierreSource :
- Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine [ 0966-0844 ] ; 2007.
English descriptors
- KwdEn :
- MESH :
- chemical , adverse effects : Citric Acid, Food Additives.
- chemical , metabolism : Citric Acid, Food Additives, Free Radicals, Hydroxyl Radical, Iron.
- metabolism : Citrus sinensis, Iron Overload.
- physiology : Oxidative Stress.
Abstract
The generation of free radicals (Fenton chemistry) from various iron citrate complexes has been studied. Spin trapping methods have been used. The results can question concerning the innocence of added citric acid in foods and cold drinks. We concluded that in absence of pathological situation citric acid is probably not dangerous but it may become dangerous in situation of oxidative stress and/or iron overload.
DOI: 10.1007/s10534-006-9042-y
PubMed: 17390216
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">The generation of free radicals (Fenton chemistry) from various iron citrate complexes has been studied. Spin trapping methods have been used. The results can question concerning the innocence of added citric acid in foods and cold drinks. We concluded that in absence of pathological situation citric acid is probably not dangerous but it may become dangerous in situation of oxidative stress and/or iron overload.</div>
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