Fruit Juices as Perpetrators of Drug Interactions: The Role of Organic Anion–Transporting Polypeptides
Identifieur interne : 001494 ( Main/Exploration ); précédent : 001493; suivant : 001495Fruit Juices as Perpetrators of Drug Interactions: The Role of Organic Anion–Transporting Polypeptides
Auteurs : M J Dolton [Australie] ; B D Roufogalis [Australie] ; A J Mclachlan [Australie]Source :
- Clinical Pharmacology & Therapeutics [ 0009-9236 ] ; 2012-11.
Abstract
Grapefruit juice is widely recognized to cause important drug interactions via inhibition of CYP3A4, and a wider variety of fruit juices have been shown to inhibit influx transporters in enterocytes known as organic anion–transporting polypeptides (OATPs). Fruit juice coadministration significantly reduces the oral bioavailability of numerous important medicines relying on this anion transporter pathway for absorption. This article reviews the current literature on interactions between clinically used OATP substrates and fruit juice consumption.
Url:
DOI: 10.1038/clpt.2012.159
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001898
- to stream Istex, to step Curation: 001897
- to stream Istex, to step Checkpoint: 000164
- to stream Main, to step Merge: 001509
- to stream Main, to step Curation: 001494
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Fruit Juices as Perpetrators of Drug Interactions: The Role of Organic Anion–Transporting Polypeptides</title>
<author><name sortKey="Dolton, M J" sort="Dolton, M J" uniqKey="Dolton M" first="M J" last="Dolton">M J Dolton</name>
</author>
<author><name sortKey="Roufogalis, B D" sort="Roufogalis, B D" uniqKey="Roufogalis B" first="B D" last="Roufogalis">B D Roufogalis</name>
</author>
<author><name sortKey="Mclachlan, A J" sort="Mclachlan, A J" uniqKey="Mclachlan A" first="A J" last="Mclachlan">A J Mclachlan</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:1B78DFFA0ED4E37CBCE7F8F0B245AF215AE26296</idno>
<date when="2012" year="2012">2012</date>
<idno type="doi">10.1038/clpt.2012.159</idno>
<idno type="url">https://api.istex.fr/document/1B78DFFA0ED4E37CBCE7F8F0B245AF215AE26296/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001898</idno>
<idno type="wicri:Area/Istex/Curation">001897</idno>
<idno type="wicri:Area/Istex/Checkpoint">000164</idno>
<idno type="wicri:doubleKey">0009-9236:2012:Dolton M:fruit:juices:as</idno>
<idno type="wicri:Area/Main/Merge">001509</idno>
<idno type="wicri:Area/Main/Curation">001494</idno>
<idno type="wicri:Area/Main/Exploration">001494</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Fruit Juices as Perpetrators of Drug Interactions: The Role of Organic Anion–Transporting Polypeptides</title>
<author><name sortKey="Dolton, M J" sort="Dolton, M J" uniqKey="Dolton M" first="M J" last="Dolton">M J Dolton</name>
<affiliation wicri:level="3"><country xml:lang="fr">Australie</country>
<wicri:regionArea>Faculty of Pharmacy, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Roufogalis, B D" sort="Roufogalis, B D" uniqKey="Roufogalis B" first="B D" last="Roufogalis">B D Roufogalis</name>
<affiliation wicri:level="3"><country xml:lang="fr">Australie</country>
<wicri:regionArea>Faculty of Pharmacy, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mclachlan, A J" sort="Mclachlan, A J" uniqKey="Mclachlan A" first="A J" last="Mclachlan">A J Mclachlan</name>
<affiliation wicri:level="3"><country xml:lang="fr">Australie</country>
<wicri:regionArea>Faculty of Pharmacy, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre For Education and Research on Ageing, Concord Repatriation General Hospital, Concord</wicri:regionArea>
<wicri:noRegion>Concord</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Clinical Pharmacology & Therapeutics</title>
<title level="j" type="abbrev">Clinical Pharmacology & Therapeutics</title>
<idno type="ISSN">0009-9236</idno>
<idno type="eISSN">1532-6535</idno>
<imprint><publisher>Blackwell Publishing Ltd</publisher>
<date type="published" when="2012-11">2012-11</date>
<biblScope unit="volume">92</biblScope>
<biblScope unit="issue">5</biblScope>
<biblScope unit="page" from="622">622</biblScope>
<biblScope unit="page" to="630">630</biblScope>
</imprint>
<idno type="ISSN">0009-9236</idno>
</series>
<idno type="istex">1B78DFFA0ED4E37CBCE7F8F0B245AF215AE26296</idno>
<idno type="DOI">10.1038/clpt.2012.159</idno>
<idno type="ArticleID">CPTCLPT2012159</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0009-9236</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract">Grapefruit juice is widely recognized to cause important drug interactions via inhibition of CYP3A4, and a wider variety of fruit juices have been shown to inhibit influx transporters in enterocytes known as organic anion–transporting polypeptides (OATPs). Fruit juice coadministration significantly reduces the oral bioavailability of numerous important medicines relying on this anion transporter pathway for absorption. This article reviews the current literature on interactions between clinically used OATP substrates and fruit juice consumption.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
</country>
<settlement><li>Sydney</li>
</settlement>
</list>
<tree><country name="Australie"><noRegion><name sortKey="Dolton, M J" sort="Dolton, M J" uniqKey="Dolton M" first="M J" last="Dolton">M J Dolton</name>
</noRegion>
<name sortKey="Mclachlan, A J" sort="Mclachlan, A J" uniqKey="Mclachlan A" first="A J" last="Mclachlan">A J Mclachlan</name>
<name sortKey="Mclachlan, A J" sort="Mclachlan, A J" uniqKey="Mclachlan A" first="A J" last="Mclachlan">A J Mclachlan</name>
<name sortKey="Roufogalis, B D" sort="Roufogalis, B D" uniqKey="Roufogalis B" first="B D" last="Roufogalis">B D Roufogalis</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Bois/explor/OrangerV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001494 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001494 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Bois |area= OrangerV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:1B78DFFA0ED4E37CBCE7F8F0B245AF215AE26296 |texte= Fruit Juices as Perpetrators of Drug Interactions: The Role of Organic Anion–Transporting Polypeptides }}
This area was generated with Dilib version V0.6.25. |