Neuroprotective Effects of Hesperidin, a Plant Flavanone, on Rotenone-Induced Oxidative Stress and Apoptosis in a Cellular Model for Parkinson's Disease
Identifieur interne : 000D74 ( Main/Curation ); précédent : 000D73; suivant : 000D75Neuroprotective Effects of Hesperidin, a Plant Flavanone, on Rotenone-Induced Oxidative Stress and Apoptosis in a Cellular Model for Parkinson's Disease
Auteurs : Kuppusamy Tamilselvam [Inde] ; Nady Braidy [Australie] ; Thamilarasan Manivasagam [Inde] ; Musthafa Mohamed Essa [Oman] ; Nagarajan Rajendra Prasad [Inde] ; Subburayan Karthikeyan [Inde] ; Arokyasamy Justin Thenmozhi [Inde] ; Subash Selvaraju [Oman] ; Gilles J. Guillemin [Australie]Source :
- Oxidative Medicine and Cellular Longevity [ 1942-0900 ] ; 2013.
Abstract
Rotenone a widely used pesticide that inhibits mitochondrial complex I has been used to investigate the pathobiology of PD both
Url:
DOI: 10.1155/2013/102741
PubMed: 24205431
PubMed Central: 3800605
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<author><name sortKey="Prasad, Nagarajan Rajendra" sort="Prasad, Nagarajan Rajendra" uniqKey="Prasad N" first="Nagarajan Rajendra" last="Prasad">Nagarajan Rajendra Prasad</name>
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<author><name sortKey="Thenmozhi, Arokyasamy Justin" sort="Thenmozhi, Arokyasamy Justin" uniqKey="Thenmozhi A" first="Arokyasamy Justin" last="Thenmozhi">Arokyasamy Justin Thenmozhi</name>
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<author><name sortKey="Guillemin, Gilles J" sort="Guillemin, Gilles J" uniqKey="Guillemin G" first="Gilles J." last="Guillemin">Gilles J. Guillemin</name>
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<series><title level="j">Oxidative Medicine and Cellular Longevity</title>
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<front><div type="abstract" xml:lang="en"><p>Rotenone a widely used pesticide that inhibits mitochondrial complex I has been used to investigate the pathobiology of PD both <italic>in vitro</italic>
and <italic>in vivo</italic>
. Studies have shown that the neurotoxicity of rotenone may be related to its ability to generate reactive oxygen species (ROS), leading to neuronal apoptosis. The current study was carried out to investigate the neuroprotective effects of hesperidin, a citrus fruit flavanol, against rotenone-induced apoptosis in human neuroblastoma SK-N-SH cells. We assessed cell death, mitochondrial membrane potential, ROS generation, ATP levels, thiobarbituric acid reactive substances, reduced glutathione (GSH) levels, and the activity of catalase, superoxide dismutase (SOD) and glutathione peroxidase (GPx) using well established assays. Apoptosis was determined in normal, rotenone, and hesperidin treated cells, by measuring the protein expression of cytochrome c (cyt c), caspases 3 and 9, Bax, and Bcl-2 using the standard western blotting technique. The apoptosis in rotenone-induced SK-N-SH cells was accompanied by the loss of mitochondrial membrane potential, increased ROS generation, the depletion of GSH, enhanced activities of enzymatic antioxidants, upregulation of Bax, cyt c, and caspases 3 and 9, and downregulation of Bcl-2, which were attenuated in the presence of hesperidin. Our data suggests that hesperidin exerts its neuroprotective effect against rotenone due to its antioxidant, maintenance of mitochondrial function, and antiapoptotic properties in a neuroblastoma cell line.</p>
</div>
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<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Dauer, W" uniqKey="Dauer W">W Dauer</name>
</author>
<author><name sortKey="Przedborski, S" uniqKey="Przedborski S">S Przedborski</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Anantharam, V" uniqKey="Anantharam V">V Anantharam</name>
</author>
<author><name sortKey="Lehrmann, E" uniqKey="Lehrmann E">E Lehrmann</name>
</author>
<author><name sortKey="Kanthasamy, A" uniqKey="Kanthasamy A">A Kanthasamy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jenner, P" uniqKey="Jenner P">P Jenner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Przedborski, S" uniqKey="Przedborski S">S Przedborski</name>
</author>
<author><name sortKey="Ischiropoulos, H" uniqKey="Ischiropoulos H">H Ischiropoulos</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Radad, K" uniqKey="Radad K">K Radad</name>
</author>
<author><name sortKey="Rausch, W D" uniqKey="Rausch W">W-D Rausch</name>
</author>
<author><name sortKey="Gille, G" uniqKey="Gille G">G Gille</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, G" uniqKey="Wang G">G Wang</name>
</author>
<author><name sortKey="Qi, C" uniqKey="Qi C">C Qi</name>
</author>
<author><name sortKey="Fan, G H" uniqKey="Fan G">G-H Fan</name>
</author>
<author><name sortKey="Zhou, H Y" uniqKey="Zhou H">H-Y Zhou</name>
</author>
<author><name sortKey="Chen, S D" uniqKey="Chen S">S-D Chen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Molina Jimenez, Mf" uniqKey="Molina Jimenez M">MF Molina-Jiménez</name>
</author>
<author><name sortKey="Sanchez Reus, Mi" uniqKey="Sanchez Reus M">MI Sánchez-Reus</name>
</author>
<author><name sortKey="Andres, D" uniqKey="Andres D">D Andres</name>
</author>
<author><name sortKey="Cascales, M" uniqKey="Cascales M">M Cascales</name>
</author>
<author><name sortKey="Benedi, J" uniqKey="Benedi J">J Benedi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Greenamyre, Jt" uniqKey="Greenamyre J">JT Greenamyre</name>
</author>
<author><name sortKey="Sherer, Tb" uniqKey="Sherer T">TB Sherer</name>
</author>
<author><name sortKey="Betarbet, R" uniqKey="Betarbet R">R Betarbet</name>
</author>
<author><name sortKey="Panov, Av" uniqKey="Panov A">AV Panov</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fukui, M" uniqKey="Fukui M">M Fukui</name>
</author>
<author><name sortKey="Choi, Hj" uniqKey="Choi H">HJ Choi</name>
</author>
<author><name sortKey="Zhu, Bt" uniqKey="Zhu B">BT Zhu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Benavente Garcisa, O" uniqKey="Benavente Garcisa O">O Benavente-Garcisa</name>
</author>
<author><name sortKey="Castillo, J" uniqKey="Castillo J">J Castillo</name>
</author>
<author><name sortKey="Marin, Fr" uniqKey="Marin F">FR Marin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Crozier, A" uniqKey="Crozier A">A Crozier</name>
</author>
<author><name sortKey="Jaganath, Ib" uniqKey="Jaganath I">IB Jaganath</name>
</author>
<author><name sortKey="Clifford, Mn" uniqKey="Clifford M">MN Clifford</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chen, M C" uniqKey="Chen M">M-C Chen</name>
</author>
<author><name sortKey="Ye, Yi" uniqKey="Ye Y">YI Ye</name>
</author>
<author><name sortKey="Guang, Ji" uniqKey="Guang J">JI Guang</name>
</author>
<author><name sortKey="Jian Wen, Liu" uniqKey="Jian Wen L">LIU Jian-Wen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cho, J" uniqKey="Cho J">J Cho</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Park, Hj" uniqKey="Park H">HJ Park</name>
</author>
<author><name sortKey="Shin, D H" uniqKey="Shin D">D-H Shin</name>
</author>
<author><name sortKey="Chung, Wj" uniqKey="Chung W">WJ Chung</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mosmann, T" uniqKey="Mosmann T">T Mosmann</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Karthikeyan, S" uniqKey="Karthikeyan S">S Karthikeyan</name>
</author>
<author><name sortKey="Kanimozhi, G" uniqKey="Kanimozhi G">G Kanimozhi</name>
</author>
<author><name sortKey="Prasad, Nr" uniqKey="Prasad N">NR Prasad</name>
</author>
<author><name sortKey="Mahalakshmi, R" uniqKey="Mahalakshmi R">R Mahalakshmi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Niehaus, Wg" uniqKey="Niehaus W">WG Niehaus</name>
</author>
<author><name sortKey="Samuelsson, B" uniqKey="Samuelsson B">B Samuelsson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kakkar, P" uniqKey="Kakkar P">P Kakkar</name>
</author>
<author><name sortKey="Das, B" uniqKey="Das B">B Das</name>
</author>
<author><name sortKey="Viswanathan, Pn" uniqKey="Viswanathan P">PN Viswanathan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Aebi, H" uniqKey="Aebi H">H Aebi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rotruck, Jt" uniqKey="Rotruck J">JT Rotruck</name>
</author>
<author><name sortKey="Pope, Al" uniqKey="Pope A">AL Pope</name>
</author>
<author><name sortKey="Ganther, He" uniqKey="Ganther H">HE Ganther</name>
</author>
<author><name sortKey="Swanson, Ab" uniqKey="Swanson A">AB Swanson</name>
</author>
<author><name sortKey="Hafeman, Dg" uniqKey="Hafeman D">DG Hafeman</name>
</author>
<author><name sortKey="Hoekstra, Wg" uniqKey="Hoekstra W">WG Hoekstra</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ellman, Gl" uniqKey="Ellman G">GL Ellman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rajendra Prasad, N" uniqKey="Rajendra Prasad N">N Rajendra Prasad</name>
</author>
<author><name sortKey="Karthikeyan, A" uniqKey="Karthikeyan A">A Karthikeyan</name>
</author>
<author><name sortKey="Karthikeyan, S" uniqKey="Karthikeyan S">S Karthikeyan</name>
</author>
<author><name sortKey="Venkata Reddy, B" uniqKey="Venkata Reddy B">B Venkata Reddy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="York, Jl" uniqKey="York J">JL York</name>
</author>
<author><name sortKey="Maddox, Lc" uniqKey="Maddox L">LC Maddox</name>
</author>
<author><name sortKey="Zimniak, P" uniqKey="Zimniak P">P Zimniak</name>
</author>
<author><name sortKey="Mchugh, Te" uniqKey="Mchugh T">TE McHugh</name>
</author>
<author><name sortKey="Grant, Df" uniqKey="Grant D">DF Grant</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Beal, Mf" uniqKey="Beal M">MF Beal</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Moon, Y" uniqKey="Moon Y">Y Moon</name>
</author>
<author><name sortKey="Lee, Kh" uniqKey="Lee K">KH Lee</name>
</author>
<author><name sortKey="Park, J H" uniqKey="Park J">J-H Park</name>
</author>
<author><name sortKey="Geum, D" uniqKey="Geum D">D Geum</name>
</author>
<author><name sortKey="Kim, K" uniqKey="Kim K">K Kim</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sherer, Tb" uniqKey="Sherer T">TB Sherer</name>
</author>
<author><name sortKey="Betarbet, R" uniqKey="Betarbet R">R Betarbet</name>
</author>
<author><name sortKey="Testa, Cm" uniqKey="Testa C">CM Testa</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Turrens, Jf" uniqKey="Turrens J">JF Turrens</name>
</author>
<author><name sortKey="Alexandre, A" uniqKey="Alexandre A">A Alexandre</name>
</author>
<author><name sortKey="Lehninger, Al" uniqKey="Lehninger A">AL Lehninger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="St Pierre, J" uniqKey="St Pierre J">J St-Pierre</name>
</author>
<author><name sortKey="Buckingham, Ja" uniqKey="Buckingham J">JA Buckingham</name>
</author>
<author><name sortKey="Roebuck, Sj" uniqKey="Roebuck S">SJ Roebuck</name>
</author>
<author><name sortKey="Brand, Md" uniqKey="Brand M">MD Brand</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fiskum, G" uniqKey="Fiskum G">G Fiskum</name>
</author>
<author><name sortKey="Rosenthal, Re" uniqKey="Rosenthal R">RE Rosenthal</name>
</author>
<author><name sortKey="Vereczki, V" uniqKey="Vereczki V">V Vereczki</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jovanovic, Sv" uniqKey="Jovanovic S">SV Jovanovic</name>
</author>
<author><name sortKey="Steenken, S" uniqKey="Steenken S">S Steenken</name>
</author>
<author><name sortKey="Tosic, M" uniqKey="Tosic M">M Tosic</name>
</author>
<author><name sortKey="Marjanovic, B" uniqKey="Marjanovic B">B Marjanovic</name>
</author>
<author><name sortKey="Simic, Mg" uniqKey="Simic M">MG Simic</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gaur, V" uniqKey="Gaur V">V Gaur</name>
</author>
<author><name sortKey="Kumar, A" uniqKey="Kumar A">A Kumar</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cassarino, Ds" uniqKey="Cassarino D">DS Cassarino</name>
</author>
<author><name sortKey="Fall, Cp" uniqKey="Fall C">CP Fall</name>
</author>
<author><name sortKey="Swerdlow, Rh" uniqKey="Swerdlow R">RH Swerdlow</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Li, X X" uniqKey="Li X">X-X Li</name>
</author>
<author><name sortKey="He, G R" uniqKey="He G">G-R He</name>
</author>
<author><name sortKey="Mu, X" uniqKey="Mu X">X Mu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eguchi, Y" uniqKey="Eguchi Y">Y Eguchi</name>
</author>
<author><name sortKey="Srinivasan, A" uniqKey="Srinivasan A">A Srinivasan</name>
</author>
<author><name sortKey="Tomaselli, Kj" uniqKey="Tomaselli K">KJ Tomaselli</name>
</author>
<author><name sortKey="Shimizu, S" uniqKey="Shimizu S">S Shimizu</name>
</author>
<author><name sortKey="Tsujimoto, Y" uniqKey="Tsujimoto Y">Y Tsujimoto</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Watabe, M" uniqKey="Watabe M">M Watabe</name>
</author>
<author><name sortKey="Nakaki, T" uniqKey="Nakaki T">T Nakaki</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Isenberg, Js" uniqKey="Isenberg J">JS Isenberg</name>
</author>
<author><name sortKey="Klaunig, Je" uniqKey="Klaunig J">JE Klaunig</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pei, W" uniqKey="Pei W">W Pei</name>
</author>
<author><name sortKey="Liou, Akf" uniqKey="Liou A">AKF Liou</name>
</author>
<author><name sortKey="Chen, J" uniqKey="Chen J">J Chen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Panov, A" uniqKey="Panov A">A Panov</name>
</author>
<author><name sortKey="Dikalov, S" uniqKey="Dikalov S">S Dikalov</name>
</author>
<author><name sortKey="Shalbuyeva, N" uniqKey="Shalbuyeva N">N Shalbuyeva</name>
</author>
<author><name sortKey="Taylor, G" uniqKey="Taylor G">G Taylor</name>
</author>
<author><name sortKey="Sherer, T" uniqKey="Sherer T">T Sherer</name>
</author>
<author><name sortKey="Greenamyre, Jt" uniqKey="Greenamyre J">JT Greenamyre</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kaufmann, T" uniqKey="Kaufmann T">T Kaufmann</name>
</author>
<author><name sortKey="Schlipf, S" uniqKey="Schlipf S">S Schlipf</name>
</author>
<author><name sortKey="Sanz, J" uniqKey="Sanz J">J Sanz</name>
</author>
<author><name sortKey="Neubert, K" uniqKey="Neubert K">K Neubert</name>
</author>
<author><name sortKey="Stein, R" uniqKey="Stein R">R Stein</name>
</author>
<author><name sortKey="Borner, C" uniqKey="Borner C">C Borner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jiang, X" uniqKey="Jiang X">X Jiang</name>
</author>
<author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yang, E" uniqKey="Yang E">E Yang</name>
</author>
<author><name sortKey="Zha, J" uniqKey="Zha J">J Zha</name>
</author>
<author><name sortKey="Jockel, J" uniqKey="Jockel J">J Jockel</name>
</author>
<author><name sortKey="Boise, Lh" uniqKey="Boise L">LH Boise</name>
</author>
<author><name sortKey="Thompson, Cb" uniqKey="Thompson C">CB Thompson</name>
</author>
<author><name sortKey="Korsmeyer, Sj" uniqKey="Korsmeyer S">SJ Korsmeyer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Reed, Jc" uniqKey="Reed J">JC Reed</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Korsmeyer, Sj" uniqKey="Korsmeyer S">SJ Korsmeyer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="De Sarno, P" uniqKey="De Sarno P">P De Sarno</name>
</author>
<author><name sortKey="Shestopal, Sa" uniqKey="Shestopal S">SA Shestopal</name>
</author>
<author><name sortKey="King, Td" uniqKey="King T">TD King</name>
</author>
<author><name sortKey="Zmijewska, A" uniqKey="Zmijewska A">A Zmijewska</name>
</author>
<author><name sortKey="Song, L" uniqKey="Song L">L Song</name>
</author>
<author><name sortKey="Jope, Rs" uniqKey="Jope R">RS Jope</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Desagher, S" uniqKey="Desagher S">S Desagher</name>
</author>
<author><name sortKey="Martinou, J C" uniqKey="Martinou J">J-C Martinou</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Budihardjo, I" uniqKey="Budihardjo I">I Budihardjo</name>
</author>
<author><name sortKey="Oliver, H" uniqKey="Oliver H">H Oliver</name>
</author>
<author><name sortKey="Lutter, M" uniqKey="Lutter M">M Lutter</name>
</author>
<author><name sortKey="Luo, X" uniqKey="Luo X">X Luo</name>
</author>
<author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kamisli, S" uniqKey="Kamisli S">S Kamisli</name>
</author>
<author><name sortKey="Ciftci, O" uniqKey="Ciftci O">O Ciftci</name>
</author>
<author><name sortKey="Kaya, K" uniqKey="Kaya K">K Kaya</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Heo, Hj" uniqKey="Heo H">HJ Heo</name>
</author>
<author><name sortKey="Kim, D O" uniqKey="Kim D">D-O Kim</name>
</author>
<author><name sortKey="Shin, Sc" uniqKey="Shin S">SC Shin</name>
</author>
<author><name sortKey="Kim, Mj" uniqKey="Kim M">MJ Kim</name>
</author>
<author><name sortKey="Kim, Bg" uniqKey="Kim B">BG Kim</name>
</author>
<author><name sortKey="Shin, D H" uniqKey="Shin D">D-H Shin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Viswanatha, Gl" uniqKey="Viswanatha G">GL Viswanatha</name>
</author>
<author><name sortKey="Shylaja, H" uniqKey="Shylaja H">H Shylaja</name>
</author>
<author><name sortKey="Sandeep Rao, Ks" uniqKey="Sandeep Rao K">KS Sandeep Rao</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vauzour, D" uniqKey="Vauzour D">D Vauzour</name>
</author>
<author><name sortKey="Vafeiadou, K" uniqKey="Vafeiadou K">K Vafeiadou</name>
</author>
<author><name sortKey="Rice Evans, C" uniqKey="Rice Evans C">C Rice-Evans</name>
</author>
<author><name sortKey="Williams, Rj" uniqKey="Williams R">RJ Williams</name>
</author>
<author><name sortKey="Spencer, Jpe" uniqKey="Spencer J">JPE Spencer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Raza, Ss" uniqKey="Raza S">SS Raza</name>
</author>
<author><name sortKey="Khan, Mm" uniqKey="Khan M">MM Khan</name>
</author>
<author><name sortKey="Ahmad, A" uniqKey="Ahmad A">A Ahmad</name>
</author>
</analytic>
</biblStruct>
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