Genetic predisposition to ductal carcinoma in situ of the breast.
Identifieur interne : 002205 ( PubMed/Curation ); précédent : 002204; suivant : 002206Genetic predisposition to ductal carcinoma in situ of the breast.
Auteurs : Christos Petridis [Royaume-Uni] ; Mark N. Brook [Royaume-Uni] ; Vandna Shah [Royaume-Uni] ; Kelly Kohut [Royaume-Uni] ; Patricia Gorman [Royaume-Uni] ; Michele Caneppele [Royaume-Uni] ; Dina Levi [Royaume-Uni] ; Efterpi Papouli [Royaume-Uni] ; Nick Orr [Royaume-Uni] ; Angela Cox [Royaume-Uni] ; Simon S. Cross [Royaume-Uni] ; Isabel Dos-Santos-Silva [Royaume-Uni] ; Julian Peto [Royaume-Uni] ; Anthony Swerdlow [Royaume-Uni] ; Minouk J. Schoemaker [Royaume-Uni] ; Manjeet K. Bolla [Royaume-Uni] ; Qin Wang [Royaume-Uni] ; Joe Dennis [Royaume-Uni] ; Kyriaki Michailidou [Royaume-Uni] ; Javier Benitez [Espagne] ; Anna González-Neira [Espagne] ; Daniel C. Tessier [Canada] ; Daniel Vincent [Canada] ; Jingmei Li [Suède] ; Jonine Figueroa [États-Unis] ; Vessela Kristensen [Norvège] ; Anne-Lise Borresen-Dale [Norvège] ; Penny Soucy [Canada] ; Jacques Simard [Canada] ; Roger L. Milne [Australie] ; Graham G. Giles [Australie] ; Sara Margolin [Suède] ; Annika Lindblom [Suède] ; Thomas Brüning [Allemagne] ; Hiltrud Brauch [Allemagne] ; Melissa C. Southey [Australie] ; John L. Hopper [Australie] ; Thilo Dörk [Allemagne] ; Natalia V. Bogdanova [Allemagne] ; Maria Kabisch [Allemagne] ; Ute Hamann [Allemagne] ; Rita K. Schmutzler [Allemagne] ; Alfons Meindl [Allemagne] ; Hermann Brenner [Allemagne] ; Volker Arndt [Allemagne] ; Robert Winqvist [Finlande] ; Katri Pylk S [Finlande] ; Peter A. Fasching [Allemagne] ; Matthias W. Beckmann [Allemagne] ; Jan Lubinski [Pologne] ; Anna Jakubowska [Pologne] ; Anna Marie Mulligan [Canada] ; Irene L. Andrulis [Canada] ; Rob A E M. Tollenaar [Pays-Bas] ; Peter Devilee [Pays-Bas] ; Loic Le Marchand [États-Unis] ; Christopher A. Haiman [États-Unis] ; Arto Mannermaa [Finlande] ; Veli-Matti Kosma [Finlande] ; Paolo Radice [Italie] ; Paolo Peterlongo [Italie] ; Frederik Marme [Allemagne] ; Barbara Burwinkel [Allemagne] ; Carolien H M. Van Deurzen [Pays-Bas] ; Antoinette Hollestelle [Pays-Bas] ; Nicola Miller [Irlande (pays)] ; Michael J. Kerin [Irlande (pays)] ; Diether Lambrechts [Belgique] ; Giuseppe Floris [Belgique] ; Jelle Wesseling [Pays-Bas] ; Henrik Flyger [Danemark] ; Stig E. Bojesen [Danemark] ; Song Yao [États-Unis] ; Christine B. Ambrosone [États-Unis] ; Georgia Chenevix-Trench [Australie] ; Thérèse Truong [France] ; Pascal Guénel [France] ; Anja Rudolph [Allemagne] ; Jenny Chang-Claude [Allemagne] ; Heli Nevanlinna [Finlande] ; Carl Blomqvist [Finlande] ; Kamila Czene [Suède] ; Judith S. Brand [Suède] ; Janet E. Olson [États-Unis] ; Fergus J. Couch [États-Unis] ; Alison M. Dunning [Royaume-Uni] ; Per Hall [Suède] ; Douglas F. Easton [Royaume-Uni] ; Paul D P. Pharoah [Royaume-Uni] ; Sarah E. Pinder [Royaume-Uni] ; Marjanka K. Schmidt [Pays-Bas] ; Ian Tomlinson [Royaume-Uni] ; Rebecca Roylance [Royaume-Uni] ; Montserrat García-Closas [Royaume-Uni] ; Elinor J. Sawyer [Royaume-Uni]Source :
- Breast cancer research : BCR [ 1465-542X ] ; 2016.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Antigène KI-67 (génétique), Carcinome canalaire du sein (anatomopathologie), Carcinome canalaire du sein (génétique), Carcinome intracanalaire non infiltrant (anatomopathologie), Carcinome intracanalaire non infiltrant (génétique), Cycline D1 (génétique), Femelle, Génotype, Humains, Polymorphisme de nucléotide simple, Protéines tumorales (génétique), Récepteur ErbB-2 (génétique), Récepteurs des oestrogènes (génétique), Récepteurs à la progestérone (génétique), Sujet âgé, Tumeurs du sein (anatomopathologie), Tumeurs du sein (génétique), Études d'associations génétiques.
- MESH :
- anatomopathologie : Carcinome canalaire du sein, Carcinome intracanalaire non infiltrant, Tumeurs du sein.
- génétique : Antigène KI-67, Carcinome canalaire du sein, Carcinome intracanalaire non infiltrant, Cycline D1, Protéines tumorales, Récepteur ErbB-2, Récepteurs des oestrogènes, Récepteurs à la progestérone, Tumeurs du sein.
- Adulte, Adulte d'âge moyen, Femelle, Génotype, Humains, Polymorphisme de nucléotide simple, Sujet âgé, Études d'associations génétiques.
English descriptors
- KwdEn :
- Adult, Aged, Breast Neoplasms (genetics), Breast Neoplasms (pathology), Carcinoma, Ductal, Breast (genetics), Carcinoma, Ductal, Breast (pathology), Carcinoma, Intraductal, Noninfiltrating (genetics), Carcinoma, Intraductal, Noninfiltrating (pathology), Cyclin D1 (genetics), Female, Genetic Association Studies, Genotype, Humans, Ki-67 Antigen (genetics), Middle Aged, Neoplasm Proteins (genetics), Polymorphism, Single Nucleotide, Receptor, ErbB-2 (genetics), Receptors, Estrogen (genetics), Receptors, Progesterone (genetics).
- MESH :
- chemical , genetics : Cyclin D1, Ki-67 Antigen, Neoplasm Proteins, Receptor, ErbB-2, Receptors, Estrogen, Receptors, Progesterone.
- genetics : Breast Neoplasms, Carcinoma, Ductal, Breast, Carcinoma, Intraductal, Noninfiltrating.
- pathology : Breast Neoplasms, Carcinoma, Ductal, Breast, Carcinoma, Intraductal, Noninfiltrating.
- Adult, Aged, Female, Genetic Association Studies, Genotype, Humans, Middle Aged, Polymorphism, Single Nucleotide.
Abstract
Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer. It is often associated with invasive ductal carcinoma (IDC), and is considered to be a non-obligate precursor of IDC. It is not clear to what extent these two forms of cancer share low-risk susceptibility loci, or whether there are differences in the strength of association for shared loci.
DOI: 10.1186/s13058-016-0675-7
PubMed: 26884359
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Julian.Peto@lshtm.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London</wicri:regionArea></affiliation></author><author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name><affiliation wicri:level="1"><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. Anthony.Swerdlow@icr.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Schoemaker, Minouk J" sort="Schoemaker, Minouk J" uniqKey="Schoemaker M" first="Minouk J" last="Schoemaker">Minouk J. Schoemaker</name><affiliation wicri:level="1"><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. minouk.schoemaker@icr.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Bolla, Manjeet K" sort="Bolla, Manjeet K" uniqKey="Bolla M" first="Manjeet K" last="Bolla">Manjeet K. Bolla</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. mkh39@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Qin" sort="Wang, Qin" uniqKey="Wang Q" first="Qin" last="Wang">Qin Wang</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. qw232@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Dennis, Joe" sort="Dennis, Joe" uniqKey="Dennis J" first="Joe" last="Dennis">Joe Dennis</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. jgd29@cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Michailidou, Kyriaki" sort="Michailidou, Kyriaki" uniqKey="Michailidou K" first="Kyriaki" last="Michailidou">Kyriaki Michailidou</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. km533@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><affiliation wicri:level="1"><nlm:affiliation>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain. jbenitez@cnio.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Gonzalez Neira, Anna" sort="Gonzalez Neira, Anna" uniqKey="Gonzalez Neira A" first="Anna" last="González-Neira">Anna González-Neira</name><affiliation wicri:level="1"><nlm:affiliation>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain. agonzalez@cnio.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Tessier, Daniel C" sort="Tessier, Daniel C" uniqKey="Tessier D" first="Daniel C" last="Tessier">Daniel C. Tessier</name><affiliation wicri:level="1"><nlm:affiliation>Centre d'innovation Génome Québec et Université McGill, Montréal, Canada. dtessier@genomequebec.com.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre d'innovation Génome Québec et Université McGill, Montréal</wicri:regionArea></affiliation></author><author><name sortKey="Vincent, Daniel" sort="Vincent, Daniel" uniqKey="Vincent D" first="Daniel" last="Vincent">Daniel Vincent</name><affiliation wicri:level="1"><nlm:affiliation>Centre d'innovation Génome Québec et Université McGill, Montréal, Canada. daniel.vincent@mail.mcgill.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre d'innovation Génome Québec et Université McGill, Montréal</wicri:regionArea></affiliation></author><author><name sortKey="Li, Jingmei" sort="Li, Jingmei" uniqKey="Li J" first="Jingmei" last="Li">Jingmei Li</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. jingmei@gmail.com.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Figueroa, Jonine" sort="Figueroa, Jonine" uniqKey="Figueroa J" first="Jonine" last="Figueroa">Jonine Figueroa</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA. figueroaj@mail.nih.gov.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway. v.n.kristensen@medisin.uio.no.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo</wicri:regionArea></affiliation></author><author><name sortKey="Borresen Dale, Anne Lise" sort="Borresen Dale, Anne Lise" uniqKey="Borresen Dale A" first="Anne-Lise" last="Borresen-Dale">Anne-Lise Borresen-Dale</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway. a.l.borresen-dale@medisin.uio.no.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo</wicri:regionArea></affiliation></author><author><name sortKey="Soucy, Penny" sort="Soucy, Penny" uniqKey="Soucy P" first="Penny" last="Soucy">Penny Soucy</name><affiliation wicri:level="1"><nlm:affiliation>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada. penny.soucy@crchudequebec.ulaval.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City</wicri:regionArea></affiliation></author><author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name><affiliation wicri:level="1"><nlm:affiliation>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada. jacques.simard@crchul.ulaval.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City</wicri:regionArea></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L" last="Milne">Roger L. Milne</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia. Roger.Milne@cancervic.org.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia. Graham.Giles@cancervic.org.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology - Pathology, Karolinska Institutet, Stockholm, Sweden. Sara.Margolin@karolinska.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology - Pathology, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. Annika.Lindblom@ki.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum, Bochum, Germany. bruening@ipa-dguv.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum, Bochum</wicri:regionArea></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation wicri:level="1"><nlm:affiliation>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany. hiltrud.brauch@ikp-stuttgart.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart</wicri:regionArea></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C" last="Southey">Melissa C. Southey</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, The University of Melbourne, Melbourne, Australia. msouthey@unimelb.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pathology, The University of Melbourne, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L" last="Hopper">John L. Hopper</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC, Australia. j.hopper@unimelb.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC</wicri:regionArea></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation wicri:level="1"><nlm:affiliation>Gynaecology Research Unit, Hannover Medical School, Hannover, Germany. doerk.thilo@mh-hannover.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Gynaecology Research Unit, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V" last="Bogdanova">Natalia V. Bogdanova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Hannover Medical School, Hannover, Germany. bogdanova.natalia@mh-hannover.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Kabisch, Maria" sort="Kabisch, Maria" uniqKey="Kabisch M" first="Maria" last="Kabisch">Maria Kabisch</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. m.kabisch@dkfz.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. u.hamann@dkfz-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K" last="Schmutzler">Rita K. Schmutzler</name><affiliation wicri:level="1"><nlm:affiliation>Center for Familial Breast and Ovarian Cancer, Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. rita.schmutzler@uk-koeln.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Familial Breast and Ovarian Cancer, Medical Faculty, University of Cologne and University Hospital Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation wicri:level="1"><nlm:affiliation>Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany. alfons.meindl@lrz.tu-muenchen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Gynaecology and Obstetrics, Technische Universität München, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation wicri:level="1"><nlm:affiliation>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. h.brenner@dkfz.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><affiliation wicri:level="1"><nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. v.arndt@dkfz.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland. robert.winqvist@oulu.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland. katri.pylkas@oulu.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A" last="Fasching">Peter A. Fasching</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. peter.fasching@uk-erlangen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen</wicri:regionArea></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W" last="Beckmann">Matthias W. Beckmann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. Fk-direktion@uk-erlangen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen</wicri:regionArea></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. lubinski@pum.edu.pl.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. aniaj@pum.edu.pl.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada. AnnaMarie.Mulligan@uhn.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto</wicri:regionArea></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="1"><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada. andrulis@lunenfeld.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto</wicri:regionArea></affiliation></author><author><name sortKey="Tollenaar, Rob A E M" sort="Tollenaar, Rob A E M" uniqKey="Tollenaar R" first="Rob A E M" last="Tollenaar">Rob A E M. Tollenaar</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands. r.a.e.m.tollenaar@lumc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Surgery, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. p.devilee@lumc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pathology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name><affiliation wicri:level="1"><nlm:affiliation>University of Hawaii Cancer Center, Honolulu, HI, USA. loic@crch.hawaii.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Hawaii Cancer Center, Honolulu, HI</wicri:regionArea></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A" last="Haiman">Christopher A. Haiman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Christopher.Haiman@med.usc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA</wicri:regionArea></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation wicri:level="1"><nlm:affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. arto.mannermaa@uef.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation wicri:level="1"><nlm:affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. veli-matti.kosma@uef.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy. paolo.radice@istitutotumori.mi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation wicri:level="1"><nlm:affiliation>IFOM, Fondazione Istituto FIRC (Italian Foundation of Cancer Research) di Oncologia Molecolare, Milan, Italy. paolo.peterlongo@ifom.eu.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>IFOM, Fondazione Istituto FIRC (Italian Foundation of Cancer Research) di Oncologia Molecolare, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Marme, Frederik" sort="Marme, Frederik" uniqKey="Marme F" first="Frederik" last="Marme">Frederik Marme</name><affiliation wicri:level="1"><nlm:affiliation>National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany. frederikmarme@gmail.com.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>National Center for Tumor Diseases, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany. Barbara.Burwinkel@med.uni-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Van Deurzen, Carolien H M" sort="Van Deurzen, Carolien H M" uniqKey="Van Deurzen C" first="Carolien H M" last="Van Deurzen">Carolien H M. Van Deurzen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands. c.h.m.vandeurzen@erasmusmc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pathology, Erasmus University Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Hollestelle, Antoinette" sort="Hollestelle, Antoinette" uniqKey="Hollestelle A" first="Antoinette" last="Hollestelle">Antoinette Hollestelle</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. a.hollestelle@erasmusmc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Miller, Nicola" sort="Miller, Nicola" uniqKey="Miller N" first="Nicola" last="Miller">Nicola Miller</name><affiliation wicri:level="1"><nlm:affiliation>School of Medicine, National University of Ireland, Galway, Ireland. nicola.miller@nuigalway.ie.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>School of Medicine, National University of Ireland, Galway</wicri:regionArea></affiliation></author><author><name sortKey="Kerin, Michael J" sort="Kerin, Michael J" uniqKey="Kerin M" first="Michael J" last="Kerin">Michael J. Kerin</name><affiliation wicri:level="1"><nlm:affiliation>School of Medicine, National University of Ireland, Galway, Ireland. michael.kerin@nuigalway.ie.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>School of Medicine, National University of Ireland, Galway</wicri:regionArea></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation wicri:level="1"><nlm:affiliation>Vesalius Research Center, VIB, Leuven, Belgium. Diether.Lambrechts@med.kuleuven.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Vesalius Research Center, VIB, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Floris, Giuseppe" sort="Floris, Giuseppe" uniqKey="Floris G" first="Giuseppe" last="Floris">Giuseppe Floris</name><affiliation wicri:level="1"><nlm:affiliation>University Hospital Gashuisberg, Leuven, Belgium. Giuseppe.Floris@uzleuven.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>University Hospital Gashuisberg, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Wesseling, Jelle" sort="Wesseling, Jelle" uniqKey="Wesseling J" first="Jelle" last="Wesseling">Jelle Wesseling</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands. j.wesseling@nki.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Flyger, Henrik" sort="Flyger, Henrik" uniqKey="Flyger H" first="Henrik" last="Flyger">Henrik Flyger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. henrik.flyger@regionh.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Herlev</wicri:regionArea></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E" last="Bojesen">Stig E. Bojesen</name><affiliation wicri:level="1"><nlm:affiliation>Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. stig.egil.bojesen@regionh.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev</wicri:regionArea></affiliation></author><author><name sortKey="Yao, Song" sort="Yao, Song" uniqKey="Yao S" first="Song" last="Yao">Song Yao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA. song.yao@roswellpark.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY</wicri:regionArea></affiliation></author><author><name sortKey="Ambrosone, Christine B" sort="Ambrosone, Christine B" uniqKey="Ambrosone C" first="Christine B" last="Ambrosone">Christine B. Ambrosone</name><affiliation wicri:level="1"><nlm:affiliation>Roswell Park Cancer Institute, Buffalo, NY, USA. Christine.ambrosone@roswellpark.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Roswell Park Cancer Institute, Buffalo, NY</wicri:regionArea></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia. Georgia.Trench@qimrberghofer.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Thérèse" last="Truong">Thérèse Truong</name><affiliation wicri:level="1"><nlm:affiliation>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France. therese.truong@inserm.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif</wicri:regionArea></affiliation></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><affiliation wicri:level="1"><nlm:affiliation>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France. pascal.guenel@inserm.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif</wicri:regionArea></affiliation></author><author><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. a.rudolph@dkfz.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. j.chang-claude@dkfz-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. Heli.Nevanlinna@hus.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. carl.blomqvist@helsinki.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. kamila.czene@ki.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Brand, Judith S" sort="Brand, Judith S" uniqKey="Brand J" first="Judith S" last="Brand">Judith S. Brand</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. judith.brand@ki.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E" last="Olson">Janet E. Olson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. olsonj@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Health Sciences Research, Mayo Clinic, Rochester, MN</wicri:regionArea></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J" last="Couch">Fergus J. Couch</name><affiliation wicri:level="1"><nlm:affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. couch.fergus@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN</wicri:regionArea></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M" last="Dunning">Alison M. Dunning</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. amd24@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Per.Hall@ki.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. dfe20@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D P" last="Pharoah">Paul D P. Pharoah</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. pp10001@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Pinder, Sarah E" sort="Pinder, Sarah E" uniqKey="Pinder S" first="Sarah E" last="Pinder">Sarah E. Pinder</name><affiliation wicri:level="1"><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. sarah.pinder@kcl.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Research Oncology, Guy's Hospital, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K" last="Schmidt">Marjanka K. Schmidt</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands. mk.schmidt@nki.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK. iant@well.ox.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Roylance, Rebecca" sort="Roylance, Rebecca" uniqKey="Roylance R" first="Rebecca" last="Roylance">Rebecca Roylance</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. r.roylance@qmul.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name><affiliation wicri:level="1"><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. montserrat.garcia-closas@nih.gov.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Sawyer, Elinor J" sort="Sawyer, Elinor J" uniqKey="Sawyer E" first="Elinor J" last="Sawyer">Elinor J. Sawyer</name><affiliation wicri:level="1"><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. elinor.sawyer@kcl.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Research Oncology, Guy's Hospital, King's College London, London</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:26884359</idno><idno type="pmid">26884359</idno><idno type="doi">10.1186/s13058-016-0675-7</idno><idno type="wicri:Area/PubMed/Corpus">002231</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002231</idno><idno type="wicri:Area/PubMed/Curation">002205</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002205</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Genetic predisposition to ductal carcinoma in situ of the breast.</title><author><name sortKey="Petridis, Christos" sort="Petridis, Christos" uniqKey="Petridis C" first="Christos" last="Petridis">Christos Petridis</name><affiliation wicri:level="1"><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. christos.petridis@kcl.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Research Oncology, Guy's Hospital, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Brook, Mark N" sort="Brook, Mark N" uniqKey="Brook M" first="Mark N" last="Brook">Mark N. Brook</name><affiliation wicri:level="1"><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. Mark.Brook@icr.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Shah, Vandna" sort="Shah, Vandna" uniqKey="Shah V" first="Vandna" last="Shah">Vandna Shah</name><affiliation wicri:level="1"><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. vandna.shah@kcl.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Research Oncology, Guy's Hospital, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Kohut, Kelly" sort="Kohut, Kelly" uniqKey="Kohut K" first="Kelly" last="Kohut">Kelly Kohut</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. kohut.kelly@gmail.com.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Gorman, Patricia" sort="Gorman, Patricia" uniqKey="Gorman P" first="Patricia" last="Gorman">Patricia Gorman</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. patricia.carlyle@me.com.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Caneppele, Michele" sort="Caneppele, Michele" uniqKey="Caneppele M" first="Michele" last="Caneppele">Michele Caneppele</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. michele.caneppele@novartis.com.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Levi, Dina" sort="Levi, Dina" uniqKey="Levi D" first="Dina" last="Levi">Dina Levi</name><affiliation wicri:level="1"><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. dinalevi@gmail.com.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Research Oncology, Guy's Hospital, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Papouli, Efterpi" sort="Papouli, Efterpi" uniqKey="Papouli E" first="Efterpi" last="Papouli">Efterpi Papouli</name><affiliation wicri:level="1"><nlm:affiliation>Biomedical Research Centre, King's College London, Guy's Hospital, London, UK. efterpi@cegx.co.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Biomedical Research Centre, King's College London, Guy's Hospital, London</wicri:regionArea></affiliation></author><author><name sortKey="Orr, Nick" sort="Orr, Nick" uniqKey="Orr N" first="Nick" last="Orr">Nick Orr</name><affiliation wicri:level="1"><nlm:affiliation>The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Nicholas.Orr@icr.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation wicri:level="1"><nlm:affiliation>Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield, UK. a.cox@shef.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield</wicri:regionArea></affiliation></author><author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S" last="Cross">Simon S. Cross</name><affiliation wicri:level="1"><nlm:affiliation>Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK. s.s.cross@sheffield.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield</wicri:regionArea></affiliation></author><author><name sortKey="Dos Santos Silva, Isabel" sort="Dos Santos Silva, Isabel" uniqKey="Dos Santos Silva I" first="Isabel" last="Dos-Santos-Silva">Isabel Dos-Santos-Silva</name><affiliation wicri:level="1"><nlm:affiliation>Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK. isabel.silva@lshtm.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London</wicri:regionArea></affiliation></author><author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name><affiliation wicri:level="1"><nlm:affiliation>Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK. Julian.Peto@lshtm.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London</wicri:regionArea></affiliation></author><author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name><affiliation wicri:level="1"><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. Anthony.Swerdlow@icr.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Schoemaker, Minouk J" sort="Schoemaker, Minouk J" uniqKey="Schoemaker M" first="Minouk J" last="Schoemaker">Minouk J. Schoemaker</name><affiliation wicri:level="1"><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. minouk.schoemaker@icr.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Bolla, Manjeet K" sort="Bolla, Manjeet K" uniqKey="Bolla M" first="Manjeet K" last="Bolla">Manjeet K. Bolla</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. mkh39@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Qin" sort="Wang, Qin" uniqKey="Wang Q" first="Qin" last="Wang">Qin Wang</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. qw232@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Dennis, Joe" sort="Dennis, Joe" uniqKey="Dennis J" first="Joe" last="Dennis">Joe Dennis</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. jgd29@cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Michailidou, Kyriaki" sort="Michailidou, Kyriaki" uniqKey="Michailidou K" first="Kyriaki" last="Michailidou">Kyriaki Michailidou</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. km533@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><affiliation wicri:level="1"><nlm:affiliation>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain. jbenitez@cnio.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Gonzalez Neira, Anna" sort="Gonzalez Neira, Anna" uniqKey="Gonzalez Neira A" first="Anna" last="González-Neira">Anna González-Neira</name><affiliation wicri:level="1"><nlm:affiliation>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain. agonzalez@cnio.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Tessier, Daniel C" sort="Tessier, Daniel C" uniqKey="Tessier D" first="Daniel C" last="Tessier">Daniel C. Tessier</name><affiliation wicri:level="1"><nlm:affiliation>Centre d'innovation Génome Québec et Université McGill, Montréal, Canada. dtessier@genomequebec.com.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre d'innovation Génome Québec et Université McGill, Montréal</wicri:regionArea></affiliation></author><author><name sortKey="Vincent, Daniel" sort="Vincent, Daniel" uniqKey="Vincent D" first="Daniel" last="Vincent">Daniel Vincent</name><affiliation wicri:level="1"><nlm:affiliation>Centre d'innovation Génome Québec et Université McGill, Montréal, Canada. daniel.vincent@mail.mcgill.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre d'innovation Génome Québec et Université McGill, Montréal</wicri:regionArea></affiliation></author><author><name sortKey="Li, Jingmei" sort="Li, Jingmei" uniqKey="Li J" first="Jingmei" last="Li">Jingmei Li</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. jingmei@gmail.com.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Figueroa, Jonine" sort="Figueroa, Jonine" uniqKey="Figueroa J" first="Jonine" last="Figueroa">Jonine Figueroa</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA. figueroaj@mail.nih.gov.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway. v.n.kristensen@medisin.uio.no.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo</wicri:regionArea></affiliation></author><author><name sortKey="Borresen Dale, Anne Lise" sort="Borresen Dale, Anne Lise" uniqKey="Borresen Dale A" first="Anne-Lise" last="Borresen-Dale">Anne-Lise Borresen-Dale</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway. a.l.borresen-dale@medisin.uio.no.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo</wicri:regionArea></affiliation></author><author><name sortKey="Soucy, Penny" sort="Soucy, Penny" uniqKey="Soucy P" first="Penny" last="Soucy">Penny Soucy</name><affiliation wicri:level="1"><nlm:affiliation>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada. penny.soucy@crchudequebec.ulaval.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City</wicri:regionArea></affiliation></author><author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name><affiliation wicri:level="1"><nlm:affiliation>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada. jacques.simard@crchul.ulaval.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City</wicri:regionArea></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L" last="Milne">Roger L. Milne</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia. Roger.Milne@cancervic.org.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia. Graham.Giles@cancervic.org.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology - Pathology, Karolinska Institutet, Stockholm, Sweden. Sara.Margolin@karolinska.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology - Pathology, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. Annika.Lindblom@ki.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum, Bochum, Germany. bruening@ipa-dguv.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum, Bochum</wicri:regionArea></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation wicri:level="1"><nlm:affiliation>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany. hiltrud.brauch@ikp-stuttgart.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart</wicri:regionArea></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C" last="Southey">Melissa C. Southey</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, The University of Melbourne, Melbourne, Australia. msouthey@unimelb.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pathology, The University of Melbourne, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L" last="Hopper">John L. Hopper</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC, Australia. j.hopper@unimelb.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC</wicri:regionArea></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation wicri:level="1"><nlm:affiliation>Gynaecology Research Unit, Hannover Medical School, Hannover, Germany. doerk.thilo@mh-hannover.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Gynaecology Research Unit, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V" last="Bogdanova">Natalia V. Bogdanova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Hannover Medical School, Hannover, Germany. bogdanova.natalia@mh-hannover.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Kabisch, Maria" sort="Kabisch, Maria" uniqKey="Kabisch M" first="Maria" last="Kabisch">Maria Kabisch</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. m.kabisch@dkfz.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation wicri:level="1"><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. u.hamann@dkfz-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K" last="Schmutzler">Rita K. Schmutzler</name><affiliation wicri:level="1"><nlm:affiliation>Center for Familial Breast and Ovarian Cancer, Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. rita.schmutzler@uk-koeln.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Familial Breast and Ovarian Cancer, Medical Faculty, University of Cologne and University Hospital Cologne, Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation wicri:level="1"><nlm:affiliation>Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany. alfons.meindl@lrz.tu-muenchen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Gynaecology and Obstetrics, Technische Universität München, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation wicri:level="1"><nlm:affiliation>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. h.brenner@dkfz.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><affiliation wicri:level="1"><nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. v.arndt@dkfz.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland. robert.winqvist@oulu.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland. katri.pylkas@oulu.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A" last="Fasching">Peter A. Fasching</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. peter.fasching@uk-erlangen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen</wicri:regionArea></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W" last="Beckmann">Matthias W. Beckmann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. Fk-direktion@uk-erlangen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen</wicri:regionArea></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. lubinski@pum.edu.pl.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. aniaj@pum.edu.pl.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada. AnnaMarie.Mulligan@uhn.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto</wicri:regionArea></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="1"><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada. andrulis@lunenfeld.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto</wicri:regionArea></affiliation></author><author><name sortKey="Tollenaar, Rob A E M" sort="Tollenaar, Rob A E M" uniqKey="Tollenaar R" first="Rob A E M" last="Tollenaar">Rob A E M. Tollenaar</name><affiliation wicri:level="1"><nlm:affiliation>Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands. r.a.e.m.tollenaar@lumc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Surgery, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. p.devilee@lumc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pathology, Leiden University Medical Center, Leiden</wicri:regionArea></affiliation></author><author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name><affiliation wicri:level="1"><nlm:affiliation>University of Hawaii Cancer Center, Honolulu, HI, USA. loic@crch.hawaii.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Hawaii Cancer Center, Honolulu, HI</wicri:regionArea></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A" last="Haiman">Christopher A. Haiman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Christopher.Haiman@med.usc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA</wicri:regionArea></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation wicri:level="1"><nlm:affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. arto.mannermaa@uef.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation wicri:level="1"><nlm:affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. veli-matti.kosma@uef.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy. paolo.radice@istitutotumori.mi.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan</wicri:regionArea></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation wicri:level="1"><nlm:affiliation>IFOM, Fondazione Istituto FIRC (Italian Foundation of Cancer Research) di Oncologia Molecolare, Milan, Italy. paolo.peterlongo@ifom.eu.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>IFOM, Fondazione Istituto FIRC (Italian Foundation of Cancer Research) di Oncologia Molecolare, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Marme, Frederik" sort="Marme, Frederik" uniqKey="Marme F" first="Frederik" last="Marme">Frederik Marme</name><affiliation wicri:level="1"><nlm:affiliation>National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany. frederikmarme@gmail.com.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>National Center for Tumor Diseases, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany. Barbara.Burwinkel@med.uni-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Van Deurzen, Carolien H M" sort="Van Deurzen, Carolien H M" uniqKey="Van Deurzen C" first="Carolien H M" last="Van Deurzen">Carolien H M. Van Deurzen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands. c.h.m.vandeurzen@erasmusmc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pathology, Erasmus University Medical Center, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Hollestelle, Antoinette" sort="Hollestelle, Antoinette" uniqKey="Hollestelle A" first="Antoinette" last="Hollestelle">Antoinette Hollestelle</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. a.hollestelle@erasmusmc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam</wicri:regionArea></affiliation></author><author><name sortKey="Miller, Nicola" sort="Miller, Nicola" uniqKey="Miller N" first="Nicola" last="Miller">Nicola Miller</name><affiliation wicri:level="1"><nlm:affiliation>School of Medicine, National University of Ireland, Galway, Ireland. nicola.miller@nuigalway.ie.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>School of Medicine, National University of Ireland, Galway</wicri:regionArea></affiliation></author><author><name sortKey="Kerin, Michael J" sort="Kerin, Michael J" uniqKey="Kerin M" first="Michael J" last="Kerin">Michael J. Kerin</name><affiliation wicri:level="1"><nlm:affiliation>School of Medicine, National University of Ireland, Galway, Ireland. michael.kerin@nuigalway.ie.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>School of Medicine, National University of Ireland, Galway</wicri:regionArea></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation wicri:level="1"><nlm:affiliation>Vesalius Research Center, VIB, Leuven, Belgium. Diether.Lambrechts@med.kuleuven.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Vesalius Research Center, VIB, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Floris, Giuseppe" sort="Floris, Giuseppe" uniqKey="Floris G" first="Giuseppe" last="Floris">Giuseppe Floris</name><affiliation wicri:level="1"><nlm:affiliation>University Hospital Gashuisberg, Leuven, Belgium. Giuseppe.Floris@uzleuven.be.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>University Hospital Gashuisberg, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Wesseling, Jelle" sort="Wesseling, Jelle" uniqKey="Wesseling J" first="Jelle" last="Wesseling">Jelle Wesseling</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands. j.wesseling@nki.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Flyger, Henrik" sort="Flyger, Henrik" uniqKey="Flyger H" first="Henrik" last="Flyger">Henrik Flyger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. henrik.flyger@regionh.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Herlev</wicri:regionArea></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E" last="Bojesen">Stig E. Bojesen</name><affiliation wicri:level="1"><nlm:affiliation>Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. stig.egil.bojesen@regionh.dk.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev</wicri:regionArea></affiliation></author><author><name sortKey="Yao, Song" sort="Yao, Song" uniqKey="Yao S" first="Song" last="Yao">Song Yao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA. song.yao@roswellpark.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY</wicri:regionArea></affiliation></author><author><name sortKey="Ambrosone, Christine B" sort="Ambrosone, Christine B" uniqKey="Ambrosone C" first="Christine B" last="Ambrosone">Christine B. Ambrosone</name><affiliation wicri:level="1"><nlm:affiliation>Roswell Park Cancer Institute, Buffalo, NY, USA. Christine.ambrosone@roswellpark.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Roswell Park Cancer Institute, Buffalo, NY</wicri:regionArea></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia. Georgia.Trench@qimrberghofer.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane</wicri:regionArea></affiliation></author><author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Thérèse" last="Truong">Thérèse Truong</name><affiliation wicri:level="1"><nlm:affiliation>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France. therese.truong@inserm.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif</wicri:regionArea></affiliation></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><affiliation wicri:level="1"><nlm:affiliation>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France. pascal.guenel@inserm.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif</wicri:regionArea></affiliation></author><author><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. a.rudolph@dkfz.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. j.chang-claude@dkfz-heidelberg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. Heli.Nevanlinna@hus.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. carl.blomqvist@helsinki.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki</wicri:regionArea></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. kamila.czene@ki.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Brand, Judith S" sort="Brand, Judith S" uniqKey="Brand J" first="Judith S" last="Brand">Judith S. Brand</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. judith.brand@ki.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E" last="Olson">Janet E. Olson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. olsonj@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Health Sciences Research, Mayo Clinic, Rochester, MN</wicri:regionArea></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J" last="Couch">Fergus J. Couch</name><affiliation wicri:level="1"><nlm:affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. couch.fergus@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN</wicri:regionArea></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M" last="Dunning">Alison M. Dunning</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. amd24@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Per.Hall@ki.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. dfe20@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D P" last="Pharoah">Paul D P. Pharoah</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. pp10001@medschl.cam.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea></affiliation></author><author><name sortKey="Pinder, Sarah E" sort="Pinder, Sarah E" uniqKey="Pinder S" first="Sarah E" last="Pinder">Sarah E. Pinder</name><affiliation wicri:level="1"><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. sarah.pinder@kcl.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Research Oncology, Guy's Hospital, King's College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K" last="Schmidt">Marjanka K. Schmidt</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands. mk.schmidt@nki.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam</wicri:regionArea></affiliation></author><author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><affiliation wicri:level="1"><nlm:affiliation>Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK. iant@well.ox.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Roylance, Rebecca" sort="Roylance, Rebecca" uniqKey="Roylance R" first="Rebecca" last="Roylance">Rebecca Roylance</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. r.roylance@qmul.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London</wicri:regionArea></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name><affiliation wicri:level="1"><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. montserrat.garcia-closas@nih.gov.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea></affiliation></author><author><name sortKey="Sawyer, Elinor J" sort="Sawyer, Elinor J" uniqKey="Sawyer E" first="Elinor J" last="Sawyer">Elinor J. Sawyer</name><affiliation wicri:level="1"><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. elinor.sawyer@kcl.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Research Oncology, Guy's Hospital, King's College London, London</wicri:regionArea></affiliation></author></analytic><series><title level="j">Breast cancer research : BCR</title><idno type="eISSN">1465-542X</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Breast Neoplasms (genetics)</term><term>Breast Neoplasms (pathology)</term><term>Carcinoma, Ductal, Breast (genetics)</term><term>Carcinoma, Ductal, Breast (pathology)</term><term>Carcinoma, Intraductal, Noninfiltrating (genetics)</term><term>Carcinoma, Intraductal, Noninfiltrating (pathology)</term><term>Cyclin D1 (genetics)</term><term>Female</term><term>Genetic Association Studies</term><term>Genotype</term><term>Humans</term><term>Ki-67 Antigen (genetics)</term><term>Middle Aged</term><term>Neoplasm Proteins (genetics)</term><term>Polymorphism, Single Nucleotide</term><term>Receptor, ErbB-2 (genetics)</term><term>Receptors, Estrogen (genetics)</term><term>Receptors, Progesterone (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Antigène KI-67 (génétique)</term><term>Carcinome canalaire du sein (anatomopathologie)</term><term>Carcinome canalaire du sein (génétique)</term><term>Carcinome intracanalaire non infiltrant (anatomopathologie)</term><term>Carcinome intracanalaire non infiltrant (génétique)</term><term>Cycline D1 (génétique)</term><term>Femelle</term><term>Génotype</term><term>Humains</term><term>Polymorphisme de nucléotide simple</term><term>Protéines tumorales (génétique)</term><term>Récepteur ErbB-2 (génétique)</term><term>Récepteurs des oestrogènes (génétique)</term><term>Récepteurs à la progestérone (génétique)</term><term>Sujet âgé</term><term>Tumeurs du sein (anatomopathologie)</term><term>Tumeurs du sein (génétique)</term><term>Études d'associations génétiques</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Cyclin D1</term><term>Ki-67 Antigen</term><term>Neoplasm Proteins</term><term>Receptor, ErbB-2</term><term>Receptors, Estrogen</term><term>Receptors, Progesterone</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Carcinome canalaire du sein</term><term>Carcinome intracanalaire non infiltrant</term><term>Tumeurs du sein</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Breast Neoplasms</term><term>Carcinoma, Ductal, Breast</term><term>Carcinoma, Intraductal, Noninfiltrating</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Antigène KI-67</term><term>Carcinome canalaire du sein</term><term>Carcinome intracanalaire non infiltrant</term><term>Cycline D1</term><term>Protéines tumorales</term><term>Récepteur ErbB-2</term><term>Récepteurs des oestrogènes</term><term>Récepteurs à la progestérone</term><term>Tumeurs du sein</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Breast Neoplasms</term><term>Carcinoma, Ductal, Breast</term><term>Carcinoma, Intraductal, Noninfiltrating</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Genetic Association Studies</term><term>Genotype</term><term>Humans</term><term>Middle Aged</term><term>Polymorphism, Single Nucleotide</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Génotype</term><term>Humains</term><term>Polymorphisme de nucléotide simple</term><term>Sujet âgé</term><term>Études d'associations génétiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer. It is often associated with invasive ductal carcinoma (IDC), and is considered to be a non-obligate precursor of IDC. It is not clear to what extent these two forms of cancer share low-risk susceptibility loci, or whether there are differences in the strength of association for shared loci.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26884359</PMID><DateCreated><Year>2016</Year><Month>02</Month><Day>17</Day></DateCreated><DateCompleted><Year>2016</Year><Month>10</Month><Day>07</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>22</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1465-542X</ISSN><JournalIssue CitedMedium="Internet"><Volume>18</Volume><Issue>1</Issue><PubDate><Year>2016</Year><Month>Feb</Month><Day>17</Day></PubDate></JournalIssue><Title>Breast cancer research : BCR</Title><ISOAbbreviation>Breast Cancer Res.</ISOAbbreviation></Journal><ArticleTitle>Genetic predisposition to ductal carcinoma in situ of the breast.</ArticleTitle><Pagination><MedlinePgn>22</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/s13058-016-0675-7</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer. It is often associated with invasive ductal carcinoma (IDC), and is considered to be a non-obligate precursor of IDC. It is not clear to what extent these two forms of cancer share low-risk susceptibility loci, or whether there are differences in the strength of association for shared loci.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">To identify genetic polymorphisms that predispose to DCIS, we pooled data from 38 studies comprising 5,067 cases of DCIS, 24,584 cases of IDC and 37,467 controls, all genotyped using the iCOGS chip.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Most (67 %) of the 76 known breast cancer predisposition loci showed an association with DCIS in the same direction as previously reported for invasive breast cancer. Case-only analysis showed no evidence for differences between associations for IDC and DCIS after considering multiple testing. Analysis by estrogen receptor (ER) status confirmed that loci associated with ER positive IDC were also associated with ER positive DCIS. Analysis of DCIS by grade suggested that two independent SNPs at 11q13.3 near CCND1 were specific to low/intermediate grade DCIS (rs75915166, rs554219). These associations with grade remained after adjusting for ER status and were also found in IDC. We found no novel DCIS-specific loci at a genome wide significance level of P < 5.0x10(-8).</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">In conclusion, this study provides the strongest evidence to date of a shared genetic susceptibility for IDC and DCIS. Studies with larger numbers of DCIS are needed to determine if IDC or DCIS specific loci exist.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Petridis</LastName><ForeName>Christos</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. christos.petridis@kcl.ac.uk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Medical and Molecular Genetics, Guy's Hospital, King's College London, London, UK. christos.petridis@kcl.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brook</LastName><ForeName>Mark N</ForeName><Initials>MN</Initials><AffiliationInfo><Affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. Mark.Brook@icr.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shah</LastName><ForeName>Vandna</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. vandna.shah@kcl.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kohut</LastName><ForeName>Kelly</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. kohut.kelly@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gorman</LastName><ForeName>Patricia</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. patricia.carlyle@me.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Caneppele</LastName><ForeName>Michele</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. michele.caneppele@novartis.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Levi</LastName><ForeName>Dina</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. dinalevi@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Papouli</LastName><ForeName>Efterpi</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Biomedical Research Centre, King's College London, Guy's Hospital, London, UK. efterpi@cegx.co.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Orr</LastName><ForeName>Nick</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Nicholas.Orr@icr.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cox</LastName><ForeName>Angela</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield, UK. a.cox@shef.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cross</LastName><ForeName>Simon S</ForeName><Initials>SS</Initials><AffiliationInfo><Affiliation>Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK. s.s.cross@sheffield.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dos-Santos-Silva</LastName><ForeName>Isabel</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK. isabel.silva@lshtm.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peto</LastName><ForeName>Julian</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK. Julian.Peto@lshtm.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Swerdlow</LastName><ForeName>Anthony</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. Anthony.Swerdlow@icr.ac.uk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Breast Cancer Research, The Institute of Cancer Research, London, UK. Anthony.Swerdlow@icr.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schoemaker</LastName><ForeName>Minouk J</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. minouk.schoemaker@icr.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bolla</LastName><ForeName>Manjeet K</ForeName><Initials>MK</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. mkh39@medschl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Qin</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. qw232@medschl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dennis</LastName><ForeName>Joe</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. jgd29@cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Michailidou</LastName><ForeName>Kyriaki</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. km533@medschl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Benitez</LastName><ForeName>Javier</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain. jbenitez@cnio.es.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centro de Investigación en Red de Enfermedades Raras, Valencia, Spain. jbenitez@cnio.es.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>González-Neira</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain. agonzalez@cnio.es.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tessier</LastName><ForeName>Daniel C</ForeName><Initials>DC</Initials><AffiliationInfo><Affiliation>Centre d'innovation Génome Québec et Université McGill, Montréal, Canada. dtessier@genomequebec.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vincent</LastName><ForeName>Daniel</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Centre d'innovation Génome Québec et Université McGill, Montréal, Canada. daniel.vincent@mail.mcgill.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Jingmei</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. jingmei@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Figueroa</LastName><ForeName>Jonine</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA. figueroaj@mail.nih.gov.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kristensen</LastName><ForeName>Vessela</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway. v.n.kristensen@medisin.uio.no.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>K.G. Jebsen Center for Breast Cancer Research, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway. v.n.kristensen@medisin.uio.no.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, Oslo, Norway. v.n.kristensen@medisin.uio.no.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Borresen-Dale</LastName><ForeName>Anne-Lise</ForeName><Initials>AL</Initials><AffiliationInfo><Affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway. a.l.borresen-dale@medisin.uio.no.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>K.G. Jebsen Center for Breast Cancer Research, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway. a.l.borresen-dale@medisin.uio.no.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Soucy</LastName><ForeName>Penny</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada. penny.soucy@crchudequebec.ulaval.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Simard</LastName><ForeName>Jacques</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada. jacques.simard@crchul.ulaval.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Milne</LastName><ForeName>Roger L</ForeName><Initials>RL</Initials><AffiliationInfo><Affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia. Roger.Milne@cancervic.org.au.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC, Australia. Roger.Milne@cancervic.org.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Giles</LastName><ForeName>Graham G</ForeName><Initials>GG</Initials><AffiliationInfo><Affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia. Graham.Giles@cancervic.org.au.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC, Australia. Graham.Giles@cancervic.org.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Margolin</LastName><ForeName>Sara</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Oncology - Pathology, Karolinska Institutet, Stockholm, Sweden. Sara.Margolin@karolinska.se.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lindblom</LastName><ForeName>Annika</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. Annika.Lindblom@ki.se.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brüning</LastName><ForeName>Thomas</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum, Bochum, Germany. bruening@ipa-dguv.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brauch</LastName><ForeName>Hiltrud</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany. hiltrud.brauch@ikp-stuttgart.de.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Tübingen, Tübingen, Germany. hiltrud.brauch@ikp-stuttgart.de.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. hiltrud.brauch@ikp-stuttgart.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Southey</LastName><ForeName>Melissa C</ForeName><Initials>MC</Initials><AffiliationInfo><Affiliation>Department of Pathology, The University of Melbourne, Melbourne, Australia. msouthey@unimelb.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hopper</LastName><ForeName>John L</ForeName><Initials>JL</Initials><AffiliationInfo><Affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC, Australia. j.hopper@unimelb.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dörk</LastName><ForeName>Thilo</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Gynaecology Research Unit, Hannover Medical School, Hannover, Germany. doerk.thilo@mh-hannover.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bogdanova</LastName><ForeName>Natalia V</ForeName><Initials>NV</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Hannover Medical School, Hannover, Germany. bogdanova.natalia@mh-hannover.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kabisch</LastName><ForeName>Maria</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. m.kabisch@dkfz.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hamann</LastName><ForeName>Ute</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. u.hamann@dkfz-heidelberg.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmutzler</LastName><ForeName>Rita K</ForeName><Initials>RK</Initials><AffiliationInfo><Affiliation>Center for Familial Breast and Ovarian Cancer, Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. rita.schmutzler@uk-koeln.de.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Center for Integrated Oncology (CIO), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. rita.schmutzler@uk-koeln.de.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. rita.schmutzler@uk-koeln.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meindl</LastName><ForeName>Alfons</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany. alfons.meindl@lrz.tu-muenchen.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brenner</LastName><ForeName>Hermann</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. h.brenner@dkfz.de.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. h.brenner@dkfz.de.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. h.brenner@dkfz.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arndt</LastName><ForeName>Volker</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. v.arndt@dkfz.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Winqvist</LastName><ForeName>Robert</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland. robert.winqvist@oulu.fi.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu, Finland. robert.winqvist@oulu.fi.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pylkäs</LastName><ForeName>Katri</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland. katri.pylkas@oulu.fi.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu, Finland. katri.pylkas@oulu.fi.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fasching</LastName><ForeName>Peter A</ForeName><Initials>PA</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. peter.fasching@uk-erlangen.de.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA, USA. peter.fasching@uk-erlangen.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Beckmann</LastName><ForeName>Matthias W</ForeName><Initials>MW</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. Fk-direktion@uk-erlangen.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lubinski</LastName><ForeName>Jan</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. lubinski@pum.edu.pl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jakubowska</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. aniaj@pum.edu.pl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mulligan</LastName><ForeName>Anna Marie</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada. AnnaMarie.Mulligan@uhn.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratory Medicine Program, University Health Network, Toronto, Canada. AnnaMarie.Mulligan@uhn.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Andrulis</LastName><ForeName>Irene L</ForeName><Initials>IL</Initials><AffiliationInfo><Affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada. andrulis@lunenfeld.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Canada. andrulis@lunenfeld.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tollenaar</LastName><ForeName>Rob A E M</ForeName><Initials>RA</Initials><AffiliationInfo><Affiliation>Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands. r.a.e.m.tollenaar@lumc.nl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Devilee</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. p.devilee@lumc.nl.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. p.devilee@lumc.nl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Le Marchand</LastName><ForeName>Loic</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>University of Hawaii Cancer Center, Honolulu, HI, USA. loic@crch.hawaii.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Haiman</LastName><ForeName>Christopher A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Christopher.Haiman@med.usc.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mannermaa</LastName><ForeName>Arto</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. arto.mannermaa@uef.fi.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland. arto.mannermaa@uef.fi.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland. arto.mannermaa@uef.fi.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kosma</LastName><ForeName>Veli-Matti</ForeName><Initials>VM</Initials><AffiliationInfo><Affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. veli-matti.kosma@uef.fi.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland. veli-matti.kosma@uef.fi.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland. veli-matti.kosma@uef.fi.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Radice</LastName><ForeName>Paolo</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy. paolo.radice@istitutotumori.mi.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peterlongo</LastName><ForeName>Paolo</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>IFOM, Fondazione Istituto FIRC (Italian Foundation of Cancer Research) di Oncologia Molecolare, Milan, Italy. paolo.peterlongo@ifom.eu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marme</LastName><ForeName>Frederik</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany. frederikmarme@gmail.com.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany. frederikmarme@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Burwinkel</LastName><ForeName>Barbara</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany. Barbara.Burwinkel@med.uni-heidelberg.de.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany. Barbara.Burwinkel@med.uni-heidelberg.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Deurzen</LastName><ForeName>Carolien H M</ForeName><Initials>CH</Initials><AffiliationInfo><Affiliation>Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands. c.h.m.vandeurzen@erasmusmc.nl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hollestelle</LastName><ForeName>Antoinette</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. a.hollestelle@erasmusmc.nl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Miller</LastName><ForeName>Nicola</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>School of Medicine, National University of Ireland, Galway, Ireland. nicola.miller@nuigalway.ie.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kerin</LastName><ForeName>Michael J</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>School of Medicine, National University of Ireland, Galway, Ireland. michael.kerin@nuigalway.ie.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lambrechts</LastName><ForeName>Diether</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Vesalius Research Center, VIB, Leuven, Belgium. Diether.Lambrechts@med.kuleuven.be.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium. Diether.Lambrechts@med.kuleuven.be.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Floris</LastName><ForeName>Giuseppe</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>University Hospital Gashuisberg, Leuven, Belgium. Giuseppe.Floris@uzleuven.be.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wesseling</LastName><ForeName>Jelle</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands. j.wesseling@nki.nl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Flyger</LastName><ForeName>Henrik</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. henrik.flyger@regionh.dk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bojesen</LastName><ForeName>Stig E</ForeName><Initials>SE</Initials><AffiliationInfo><Affiliation>Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. stig.egil.bojesen@regionh.dk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. stig.egil.bojesen@regionh.dk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. stig.egil.bojesen@regionh.dk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yao</LastName><ForeName>Song</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA. song.yao@roswellpark.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ambrosone</LastName><ForeName>Christine B</ForeName><Initials>CB</Initials><AffiliationInfo><Affiliation>Roswell Park Cancer Institute, Buffalo, NY, USA. Christine.ambrosone@roswellpark.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chenevix-Trench</LastName><ForeName>Georgia</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia. Georgia.Trench@qimrberghofer.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Truong</LastName><ForeName>Thérèse</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France. therese.truong@inserm.fr.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University Paris-Sud, Villejuif, France. therese.truong@inserm.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guénel</LastName><ForeName>Pascal</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France. pascal.guenel@inserm.fr.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University Paris-Sud, Villejuif, France. pascal.guenel@inserm.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rudolph</LastName><ForeName>Anja</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. a.rudolph@dkfz.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chang-Claude</LastName><ForeName>Jenny</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. j.chang-claude@dkfz-heidelberg.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nevanlinna</LastName><ForeName>Heli</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. Heli.Nevanlinna@hus.fi.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Blomqvist</LastName><ForeName>Carl</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. carl.blomqvist@helsinki.fi.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Czene</LastName><ForeName>Kamila</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. kamila.czene@ki.se.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brand</LastName><ForeName>Judith S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. judith.brand@ki.se.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Olson</LastName><ForeName>Janet E</ForeName><Initials>JE</Initials><AffiliationInfo><Affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. olsonj@mayo.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Couch</LastName><ForeName>Fergus J</ForeName><Initials>FJ</Initials><AffiliationInfo><Affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. couch.fergus@mayo.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dunning</LastName><ForeName>Alison M</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. amd24@medschl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hall</LastName><ForeName>Per</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Per.Hall@ki.se.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Easton</LastName><ForeName>Douglas F</ForeName><Initials>DF</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. dfe20@medschl.cam.ac.uk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. dfe20@medschl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pharoah</LastName><ForeName>Paul D P</ForeName><Initials>PD</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. pp10001@medschl.cam.ac.uk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. pp10001@medschl.cam.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pinder</LastName><ForeName>Sarah E</ForeName><Initials>SE</Initials><AffiliationInfo><Affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. sarah.pinder@kcl.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Marjanka K</ForeName><Initials>MK</Initials><AffiliationInfo><Affiliation>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands. mk.schmidt@nki.nl.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tomlinson</LastName><ForeName>Ian</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK. iant@well.ox.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Roylance</LastName><ForeName>Rebecca</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. r.roylance@qmul.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>García-Closas</LastName><ForeName>Montserrat</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. montserrat.garcia-closas@nih.gov.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA. montserrat.garcia-closas@nih.gov.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sawyer</LastName><ForeName>Elinor J</ForeName><Initials>EJ</Initials><AffiliationInfo><Affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. elinor.sawyer@kcl.ac.uk.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>090532/Z/09/Z</GrantID><Agency>Wellcome Trust</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>CA54281</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>MC_PC_14105</GrantID><Agency>Medical Research Council</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>CA116201</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>CA128978</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 CA176785</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>P30 CA016056</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C5047/A10692</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>UM1 CA164920</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C1287/A12014</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>P30 CA016056-32</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C490/A10124</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>CA63464</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 CA116167</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C5047/A8384</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>C12292/A11174</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 CA128978</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>CA116167</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><Agency>Canadian Institutes of Health Research</Agency><Country>Canada</Country></Grant><Grant><GrantID>CA176785</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U19 CA148537</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 CA116167</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>P50 CA116201</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C8197/A16565</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 CA063464</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C1287/A 10710</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 CA054281</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 CA063464</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 CA132839</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C1281/A12014</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>U19 CA148112</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 CA098758</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>CA132839</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U19 CA148065</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C1287/A10118</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>CA098758</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 CA164973</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R37 CA054281</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C5047/A15007</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>10124</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>02</Month><Day>17</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Breast Cancer Res</MedlineTA><NlmUniqueID>100927353</NlmUniqueID><ISSNLinking>1465-5411</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C530104">CCND1 protein, human</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D019394">Ki-67 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