Genetic predisposition to ductal carcinoma in situ of the breast.
Identifieur interne : 002231 ( PubMed/Corpus ); précédent : 002230; suivant : 002232Genetic predisposition to ductal carcinoma in situ of the breast.
Auteurs : Christos Petridis ; Mark N. Brook ; Vandna Shah ; Kelly Kohut ; Patricia Gorman ; Michele Caneppele ; Dina Levi ; Efterpi Papouli ; Nick Orr ; Angela Cox ; Simon S. Cross ; Isabel Dos-Santos-Silva ; Julian Peto ; Anthony Swerdlow ; Minouk J. Schoemaker ; Manjeet K. Bolla ; Qin Wang ; Joe Dennis ; Kyriaki Michailidou ; Javier Benitez ; Anna González-Neira ; Daniel C. Tessier ; Daniel Vincent ; Jingmei Li ; Jonine Figueroa ; Vessela Kristensen ; Anne-Lise Borresen-Dale ; Penny Soucy ; Jacques Simard ; Roger L. Milne ; Graham G. Giles ; Sara Margolin ; Annika Lindblom ; Thomas Brüning ; Hiltrud Brauch ; Melissa C. Southey ; John L. Hopper ; Thilo Dörk ; Natalia V. Bogdanova ; Maria Kabisch ; Ute Hamann ; Rita K. Schmutzler ; Alfons Meindl ; Hermann Brenner ; Volker Arndt ; Robert Winqvist ; Katri Pylk S ; Peter A. Fasching ; Matthias W. Beckmann ; Jan Lubinski ; Anna Jakubowska ; Anna Marie Mulligan ; Irene L. Andrulis ; Rob A E M. Tollenaar ; Peter Devilee ; Loic Le Marchand ; Christopher A. Haiman ; Arto Mannermaa ; Veli-Matti Kosma ; Paolo Radice ; Paolo Peterlongo ; Frederik Marme ; Barbara Burwinkel ; Carolien H M. Van Deurzen ; Antoinette Hollestelle ; Nicola Miller ; Michael J. Kerin ; Diether Lambrechts ; Giuseppe Floris ; Jelle Wesseling ; Henrik Flyger ; Stig E. Bojesen ; Song Yao ; Christine B. Ambrosone ; Georgia Chenevix-Trench ; Thérèse Truong ; Pascal Guénel ; Anja Rudolph ; Jenny Chang-Claude ; Heli Nevanlinna ; Carl Blomqvist ; Kamila Czene ; Judith S. Brand ; Janet E. Olson ; Fergus J. Couch ; Alison M. Dunning ; Per Hall ; Douglas F. Easton ; Paul D P. Pharoah ; Sarah E. Pinder ; Marjanka K. Schmidt ; Ian Tomlinson ; Rebecca Roylance ; Montserrat García-Closas ; Elinor J. SawyerSource :
- Breast cancer research : BCR [ 1465-542X ] ; 2016.
English descriptors
- KwdEn :
- Adult, Aged, Breast Neoplasms (genetics), Breast Neoplasms (pathology), Carcinoma, Ductal, Breast (genetics), Carcinoma, Ductal, Breast (pathology), Carcinoma, Intraductal, Noninfiltrating (genetics), Carcinoma, Intraductal, Noninfiltrating (pathology), Cyclin D1 (genetics), Female, Genetic Association Studies, Genotype, Humans, Ki-67 Antigen (genetics), Middle Aged, Neoplasm Proteins (genetics), Polymorphism, Single Nucleotide, Receptor, ErbB-2 (genetics), Receptors, Estrogen (genetics), Receptors, Progesterone (genetics).
- MESH :
- chemical , genetics : Cyclin D1, Ki-67 Antigen, Neoplasm Proteins, Receptor, ErbB-2, Receptors, Estrogen, Receptors, Progesterone.
- genetics : Breast Neoplasms, Carcinoma, Ductal, Breast, Carcinoma, Intraductal, Noninfiltrating.
- pathology : Breast Neoplasms, Carcinoma, Ductal, Breast, Carcinoma, Intraductal, Noninfiltrating.
- Adult, Aged, Female, Genetic Association Studies, Genotype, Humans, Middle Aged, Polymorphism, Single Nucleotide.
Abstract
Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer. It is often associated with invasive ductal carcinoma (IDC), and is considered to be a non-obligate precursor of IDC. It is not clear to what extent these two forms of cancer share low-risk susceptibility loci, or whether there are differences in the strength of association for shared loci.
DOI: 10.1186/s13058-016-0675-7
PubMed: 26884359
Links to Exploration step
pubmed:26884359Le document en format XML
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<author><name sortKey="Petridis, Christos" sort="Petridis, Christos" uniqKey="Petridis C" first="Christos" last="Petridis">Christos Petridis</name>
<affiliation><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. christos.petridis@kcl.ac.uk.</nlm:affiliation>
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<author><name sortKey="Brook, Mark N" sort="Brook, Mark N" uniqKey="Brook M" first="Mark N" last="Brook">Mark N. Brook</name>
<affiliation><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. Mark.Brook@icr.ac.uk.</nlm:affiliation>
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<author><name sortKey="Shah, Vandna" sort="Shah, Vandna" uniqKey="Shah V" first="Vandna" last="Shah">Vandna Shah</name>
<affiliation><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. vandna.shah@kcl.ac.uk.</nlm:affiliation>
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<author><name sortKey="Kohut, Kelly" sort="Kohut, Kelly" uniqKey="Kohut K" first="Kelly" last="Kohut">Kelly Kohut</name>
<affiliation><nlm:affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. kohut.kelly@gmail.com.</nlm:affiliation>
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<author><name sortKey="Gorman, Patricia" sort="Gorman, Patricia" uniqKey="Gorman P" first="Patricia" last="Gorman">Patricia Gorman</name>
<affiliation><nlm:affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. patricia.carlyle@me.com.</nlm:affiliation>
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<author><name sortKey="Caneppele, Michele" sort="Caneppele, Michele" uniqKey="Caneppele M" first="Michele" last="Caneppele">Michele Caneppele</name>
<affiliation><nlm:affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. michele.caneppele@novartis.com.</nlm:affiliation>
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<author><name sortKey="Levi, Dina" sort="Levi, Dina" uniqKey="Levi D" first="Dina" last="Levi">Dina Levi</name>
<affiliation><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. dinalevi@gmail.com.</nlm:affiliation>
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<author><name sortKey="Papouli, Efterpi" sort="Papouli, Efterpi" uniqKey="Papouli E" first="Efterpi" last="Papouli">Efterpi Papouli</name>
<affiliation><nlm:affiliation>Biomedical Research Centre, King's College London, Guy's Hospital, London, UK. efterpi@cegx.co.uk.</nlm:affiliation>
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<author><name sortKey="Orr, Nick" sort="Orr, Nick" uniqKey="Orr N" first="Nick" last="Orr">Nick Orr</name>
<affiliation><nlm:affiliation>The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK. Nicholas.Orr@icr.ac.uk.</nlm:affiliation>
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</author>
<author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name>
<affiliation><nlm:affiliation>Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield, UK. a.cox@shef.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S" last="Cross">Simon S. Cross</name>
<affiliation><nlm:affiliation>Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK. s.s.cross@sheffield.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Dos Santos Silva, Isabel" sort="Dos Santos Silva, Isabel" uniqKey="Dos Santos Silva I" first="Isabel" last="Dos-Santos-Silva">Isabel Dos-Santos-Silva</name>
<affiliation><nlm:affiliation>Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK. isabel.silva@lshtm.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name>
<affiliation><nlm:affiliation>Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK. Julian.Peto@lshtm.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name>
<affiliation><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. Anthony.Swerdlow@icr.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Schoemaker, Minouk J" sort="Schoemaker, Minouk J" uniqKey="Schoemaker M" first="Minouk J" last="Schoemaker">Minouk J. Schoemaker</name>
<affiliation><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. minouk.schoemaker@icr.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bolla, Manjeet K" sort="Bolla, Manjeet K" uniqKey="Bolla M" first="Manjeet K" last="Bolla">Manjeet K. Bolla</name>
<affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. mkh39@medschl.cam.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wang, Qin" sort="Wang, Qin" uniqKey="Wang Q" first="Qin" last="Wang">Qin Wang</name>
<affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. qw232@medschl.cam.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Dennis, Joe" sort="Dennis, Joe" uniqKey="Dennis J" first="Joe" last="Dennis">Joe Dennis</name>
<affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. jgd29@cam.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Michailidou, Kyriaki" sort="Michailidou, Kyriaki" uniqKey="Michailidou K" first="Kyriaki" last="Michailidou">Kyriaki Michailidou</name>
<affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. km533@medschl.cam.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name>
<affiliation><nlm:affiliation>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain. jbenitez@cnio.es.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Gonzalez Neira, Anna" sort="Gonzalez Neira, Anna" uniqKey="Gonzalez Neira A" first="Anna" last="González-Neira">Anna González-Neira</name>
<affiliation><nlm:affiliation>Human Cancer Genetics Program, Spanish National Cancer Research Centre, Madrid, Spain. agonzalez@cnio.es.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tessier, Daniel C" sort="Tessier, Daniel C" uniqKey="Tessier D" first="Daniel C" last="Tessier">Daniel C. Tessier</name>
<affiliation><nlm:affiliation>Centre d'innovation Génome Québec et Université McGill, Montréal, Canada. dtessier@genomequebec.com.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Vincent, Daniel" sort="Vincent, Daniel" uniqKey="Vincent D" first="Daniel" last="Vincent">Daniel Vincent</name>
<affiliation><nlm:affiliation>Centre d'innovation Génome Québec et Université McGill, Montréal, Canada. daniel.vincent@mail.mcgill.ca.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Li, Jingmei" sort="Li, Jingmei" uniqKey="Li J" first="Jingmei" last="Li">Jingmei Li</name>
<affiliation><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. jingmei@gmail.com.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Figueroa, Jonine" sort="Figueroa, Jonine" uniqKey="Figueroa J" first="Jonine" last="Figueroa">Jonine Figueroa</name>
<affiliation><nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA. figueroaj@mail.nih.gov.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name>
<affiliation><nlm:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway. v.n.kristensen@medisin.uio.no.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Borresen Dale, Anne Lise" sort="Borresen Dale, Anne Lise" uniqKey="Borresen Dale A" first="Anne-Lise" last="Borresen-Dale">Anne-Lise Borresen-Dale</name>
<affiliation><nlm:affiliation>Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway. a.l.borresen-dale@medisin.uio.no.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Soucy, Penny" sort="Soucy, Penny" uniqKey="Soucy P" first="Penny" last="Soucy">Penny Soucy</name>
<affiliation><nlm:affiliation>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada. penny.soucy@crchudequebec.ulaval.ca.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name>
<affiliation><nlm:affiliation>Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada. jacques.simard@crchul.ulaval.ca.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L" last="Milne">Roger L. Milne</name>
<affiliation><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia. Roger.Milne@cancervic.org.au.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name>
<affiliation><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia. Graham.Giles@cancervic.org.au.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name>
<affiliation><nlm:affiliation>Department of Oncology - Pathology, Karolinska Institutet, Stockholm, Sweden. Sara.Margolin@karolinska.se.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name>
<affiliation><nlm:affiliation>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. Annika.Lindblom@ki.se.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name>
<affiliation><nlm:affiliation>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum, Bochum, Germany. bruening@ipa-dguv.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name>
<affiliation><nlm:affiliation>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany. hiltrud.brauch@ikp-stuttgart.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C" last="Southey">Melissa C. Southey</name>
<affiliation><nlm:affiliation>Department of Pathology, The University of Melbourne, Melbourne, Australia. msouthey@unimelb.edu.au.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L" last="Hopper">John L. Hopper</name>
<affiliation><nlm:affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC, Australia. j.hopper@unimelb.edu.au.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name>
<affiliation><nlm:affiliation>Gynaecology Research Unit, Hannover Medical School, Hannover, Germany. doerk.thilo@mh-hannover.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V" last="Bogdanova">Natalia V. Bogdanova</name>
<affiliation><nlm:affiliation>Department of Radiation Oncology, Hannover Medical School, Hannover, Germany. bogdanova.natalia@mh-hannover.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kabisch, Maria" sort="Kabisch, Maria" uniqKey="Kabisch M" first="Maria" last="Kabisch">Maria Kabisch</name>
<affiliation><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. m.kabisch@dkfz.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name>
<affiliation><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. u.hamann@dkfz-heidelberg.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K" last="Schmutzler">Rita K. Schmutzler</name>
<affiliation><nlm:affiliation>Center for Familial Breast and Ovarian Cancer, Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. rita.schmutzler@uk-koeln.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name>
<affiliation><nlm:affiliation>Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany. alfons.meindl@lrz.tu-muenchen.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name>
<affiliation><nlm:affiliation>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. h.brenner@dkfz.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name>
<affiliation><nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. v.arndt@dkfz.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name>
<affiliation><nlm:affiliation>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland. robert.winqvist@oulu.fi.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name>
<affiliation><nlm:affiliation>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland. katri.pylkas@oulu.fi.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A" last="Fasching">Peter A. Fasching</name>
<affiliation><nlm:affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. peter.fasching@uk-erlangen.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W" last="Beckmann">Matthias W. Beckmann</name>
<affiliation><nlm:affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. Fk-direktion@uk-erlangen.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name>
<affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. lubinski@pum.edu.pl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name>
<affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. aniaj@pum.edu.pl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name>
<affiliation><nlm:affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada. AnnaMarie.Mulligan@uhn.ca.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name>
<affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada. andrulis@lunenfeld.ca.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tollenaar, Rob A E M" sort="Tollenaar, Rob A E M" uniqKey="Tollenaar R" first="Rob A E M" last="Tollenaar">Rob A E M. Tollenaar</name>
<affiliation><nlm:affiliation>Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands. r.a.e.m.tollenaar@lumc.nl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name>
<affiliation><nlm:affiliation>Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. p.devilee@lumc.nl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name>
<affiliation><nlm:affiliation>University of Hawaii Cancer Center, Honolulu, HI, USA. loic@crch.hawaii.edu.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A" last="Haiman">Christopher A. Haiman</name>
<affiliation><nlm:affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Christopher.Haiman@med.usc.edu.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name>
<affiliation><nlm:affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. arto.mannermaa@uef.fi.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name>
<affiliation><nlm:affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. veli-matti.kosma@uef.fi.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name>
<affiliation><nlm:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy. paolo.radice@istitutotumori.mi.it.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name>
<affiliation><nlm:affiliation>IFOM, Fondazione Istituto FIRC (Italian Foundation of Cancer Research) di Oncologia Molecolare, Milan, Italy. paolo.peterlongo@ifom.eu.</nlm:affiliation>
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<affiliation><nlm:affiliation>National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany. frederikmarme@gmail.com.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany. Barbara.Burwinkel@med.uni-heidelberg.de.</nlm:affiliation>
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<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:26884359</idno>
<idno type="pmid">26884359</idno>
<idno type="doi">10.1186/s13058-016-0675-7</idno>
<idno type="wicri:Area/PubMed/Corpus">002231</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002231</idno>
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</author>
<author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C" last="Southey">Melissa C. Southey</name>
<affiliation><nlm:affiliation>Department of Pathology, The University of Melbourne, Melbourne, Australia. msouthey@unimelb.edu.au.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L" last="Hopper">John L. Hopper</name>
<affiliation><nlm:affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC, Australia. j.hopper@unimelb.edu.au.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name>
<affiliation><nlm:affiliation>Gynaecology Research Unit, Hannover Medical School, Hannover, Germany. doerk.thilo@mh-hannover.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V" last="Bogdanova">Natalia V. Bogdanova</name>
<affiliation><nlm:affiliation>Department of Radiation Oncology, Hannover Medical School, Hannover, Germany. bogdanova.natalia@mh-hannover.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kabisch, Maria" sort="Kabisch, Maria" uniqKey="Kabisch M" first="Maria" last="Kabisch">Maria Kabisch</name>
<affiliation><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. m.kabisch@dkfz.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name>
<affiliation><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. u.hamann@dkfz-heidelberg.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K" last="Schmutzler">Rita K. Schmutzler</name>
<affiliation><nlm:affiliation>Center for Familial Breast and Ovarian Cancer, Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. rita.schmutzler@uk-koeln.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name>
<affiliation><nlm:affiliation>Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany. alfons.meindl@lrz.tu-muenchen.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name>
<affiliation><nlm:affiliation>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. h.brenner@dkfz.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name>
<affiliation><nlm:affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. v.arndt@dkfz.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name>
<affiliation><nlm:affiliation>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland. robert.winqvist@oulu.fi.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name>
<affiliation><nlm:affiliation>Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland. katri.pylkas@oulu.fi.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A" last="Fasching">Peter A. Fasching</name>
<affiliation><nlm:affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. peter.fasching@uk-erlangen.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W" last="Beckmann">Matthias W. Beckmann</name>
<affiliation><nlm:affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. Fk-direktion@uk-erlangen.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name>
<affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. lubinski@pum.edu.pl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name>
<affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. aniaj@pum.edu.pl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name>
<affiliation><nlm:affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada. AnnaMarie.Mulligan@uhn.ca.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name>
<affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada. andrulis@lunenfeld.ca.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tollenaar, Rob A E M" sort="Tollenaar, Rob A E M" uniqKey="Tollenaar R" first="Rob A E M" last="Tollenaar">Rob A E M. Tollenaar</name>
<affiliation><nlm:affiliation>Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands. r.a.e.m.tollenaar@lumc.nl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name>
<affiliation><nlm:affiliation>Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. p.devilee@lumc.nl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name>
<affiliation><nlm:affiliation>University of Hawaii Cancer Center, Honolulu, HI, USA. loic@crch.hawaii.edu.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A" last="Haiman">Christopher A. Haiman</name>
<affiliation><nlm:affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Christopher.Haiman@med.usc.edu.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name>
<affiliation><nlm:affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. arto.mannermaa@uef.fi.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name>
<affiliation><nlm:affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. veli-matti.kosma@uef.fi.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name>
<affiliation><nlm:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy. paolo.radice@istitutotumori.mi.it.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name>
<affiliation><nlm:affiliation>IFOM, Fondazione Istituto FIRC (Italian Foundation of Cancer Research) di Oncologia Molecolare, Milan, Italy. paolo.peterlongo@ifom.eu.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Marme, Frederik" sort="Marme, Frederik" uniqKey="Marme F" first="Frederik" last="Marme">Frederik Marme</name>
<affiliation><nlm:affiliation>National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany. frederikmarme@gmail.com.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name>
<affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany. Barbara.Burwinkel@med.uni-heidelberg.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Van Deurzen, Carolien H M" sort="Van Deurzen, Carolien H M" uniqKey="Van Deurzen C" first="Carolien H M" last="Van Deurzen">Carolien H M. Van Deurzen</name>
<affiliation><nlm:affiliation>Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands. c.h.m.vandeurzen@erasmusmc.nl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hollestelle, Antoinette" sort="Hollestelle, Antoinette" uniqKey="Hollestelle A" first="Antoinette" last="Hollestelle">Antoinette Hollestelle</name>
<affiliation><nlm:affiliation>Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. a.hollestelle@erasmusmc.nl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Miller, Nicola" sort="Miller, Nicola" uniqKey="Miller N" first="Nicola" last="Miller">Nicola Miller</name>
<affiliation><nlm:affiliation>School of Medicine, National University of Ireland, Galway, Ireland. nicola.miller@nuigalway.ie.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Kerin, Michael J" sort="Kerin, Michael J" uniqKey="Kerin M" first="Michael J" last="Kerin">Michael J. Kerin</name>
<affiliation><nlm:affiliation>School of Medicine, National University of Ireland, Galway, Ireland. michael.kerin@nuigalway.ie.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name>
<affiliation><nlm:affiliation>Vesalius Research Center, VIB, Leuven, Belgium. Diether.Lambrechts@med.kuleuven.be.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Floris, Giuseppe" sort="Floris, Giuseppe" uniqKey="Floris G" first="Giuseppe" last="Floris">Giuseppe Floris</name>
<affiliation><nlm:affiliation>University Hospital Gashuisberg, Leuven, Belgium. Giuseppe.Floris@uzleuven.be.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wesseling, Jelle" sort="Wesseling, Jelle" uniqKey="Wesseling J" first="Jelle" last="Wesseling">Jelle Wesseling</name>
<affiliation><nlm:affiliation>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands. j.wesseling@nki.nl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Flyger, Henrik" sort="Flyger, Henrik" uniqKey="Flyger H" first="Henrik" last="Flyger">Henrik Flyger</name>
<affiliation><nlm:affiliation>Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. henrik.flyger@regionh.dk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E" last="Bojesen">Stig E. Bojesen</name>
<affiliation><nlm:affiliation>Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. stig.egil.bojesen@regionh.dk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Yao, Song" sort="Yao, Song" uniqKey="Yao S" first="Song" last="Yao">Song Yao</name>
<affiliation><nlm:affiliation>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA. song.yao@roswellpark.org.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ambrosone, Christine B" sort="Ambrosone, Christine B" uniqKey="Ambrosone C" first="Christine B" last="Ambrosone">Christine B. Ambrosone</name>
<affiliation><nlm:affiliation>Roswell Park Cancer Institute, Buffalo, NY, USA. Christine.ambrosone@roswellpark.org.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name>
<affiliation><nlm:affiliation>Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia. Georgia.Trench@qimrberghofer.edu.au.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Thérèse" last="Truong">Thérèse Truong</name>
<affiliation><nlm:affiliation>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France. therese.truong@inserm.fr.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name>
<affiliation><nlm:affiliation>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France. pascal.guenel@inserm.fr.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name>
<affiliation><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. a.rudolph@dkfz.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name>
<affiliation><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. j.chang-claude@dkfz-heidelberg.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name>
<affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. Heli.Nevanlinna@hus.fi.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name>
<affiliation><nlm:affiliation>Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. carl.blomqvist@helsinki.fi.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name>
<affiliation><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. kamila.czene@ki.se.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Brand, Judith S" sort="Brand, Judith S" uniqKey="Brand J" first="Judith S" last="Brand">Judith S. Brand</name>
<affiliation><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. judith.brand@ki.se.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E" last="Olson">Janet E. Olson</name>
<affiliation><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. olsonj@mayo.edu.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J" last="Couch">Fergus J. Couch</name>
<affiliation><nlm:affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. couch.fergus@mayo.edu.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M" last="Dunning">Alison M. Dunning</name>
<affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. amd24@medschl.cam.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name>
<affiliation><nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Per.Hall@ki.se.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name>
<affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. dfe20@medschl.cam.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D P" last="Pharoah">Paul D P. Pharoah</name>
<affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. pp10001@medschl.cam.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pinder, Sarah E" sort="Pinder, Sarah E" uniqKey="Pinder S" first="Sarah E" last="Pinder">Sarah E. Pinder</name>
<affiliation><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. sarah.pinder@kcl.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K" last="Schmidt">Marjanka K. Schmidt</name>
<affiliation><nlm:affiliation>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands. mk.schmidt@nki.nl.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name>
<affiliation><nlm:affiliation>Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK. iant@well.ox.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Roylance, Rebecca" sort="Roylance, Rebecca" uniqKey="Roylance R" first="Rebecca" last="Roylance">Rebecca Roylance</name>
<affiliation><nlm:affiliation>Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. r.roylance@qmul.ac.uk.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name>
<affiliation><nlm:affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. montserrat.garcia-closas@nih.gov.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Sawyer, Elinor J" sort="Sawyer, Elinor J" uniqKey="Sawyer E" first="Elinor J" last="Sawyer">Elinor J. Sawyer</name>
<affiliation><nlm:affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. elinor.sawyer@kcl.ac.uk.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series><title level="j">Breast cancer research : BCR</title>
<idno type="eISSN">1465-542X</idno>
<imprint><date when="2016" type="published">2016</date>
</imprint>
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<term>Aged</term>
<term>Breast Neoplasms (genetics)</term>
<term>Breast Neoplasms (pathology)</term>
<term>Carcinoma, Ductal, Breast (genetics)</term>
<term>Carcinoma, Ductal, Breast (pathology)</term>
<term>Carcinoma, Intraductal, Noninfiltrating (genetics)</term>
<term>Carcinoma, Intraductal, Noninfiltrating (pathology)</term>
<term>Cyclin D1 (genetics)</term>
<term>Female</term>
<term>Genetic Association Studies</term>
<term>Genotype</term>
<term>Humans</term>
<term>Ki-67 Antigen (genetics)</term>
<term>Middle Aged</term>
<term>Neoplasm Proteins (genetics)</term>
<term>Polymorphism, Single Nucleotide</term>
<term>Receptor, ErbB-2 (genetics)</term>
<term>Receptors, Estrogen (genetics)</term>
<term>Receptors, Progesterone (genetics)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Cyclin D1</term>
<term>Ki-67 Antigen</term>
<term>Neoplasm Proteins</term>
<term>Receptor, ErbB-2</term>
<term>Receptors, Estrogen</term>
<term>Receptors, Progesterone</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Breast Neoplasms</term>
<term>Carcinoma, Ductal, Breast</term>
<term>Carcinoma, Intraductal, Noninfiltrating</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Breast Neoplasms</term>
<term>Carcinoma, Ductal, Breast</term>
<term>Carcinoma, Intraductal, Noninfiltrating</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Genetic Association Studies</term>
<term>Genotype</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Polymorphism, Single Nucleotide</term>
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<front><div type="abstract" xml:lang="en">Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer. It is often associated with invasive ductal carcinoma (IDC), and is considered to be a non-obligate precursor of IDC. It is not clear to what extent these two forms of cancer share low-risk susceptibility loci, or whether there are differences in the strength of association for shared loci.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26884359</PMID>
<DateCreated><Year>2016</Year>
<Month>02</Month>
<Day>17</Day>
</DateCreated>
<DateCompleted><Year>2016</Year>
<Month>10</Month>
<Day>07</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>09</Month>
<Day>22</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1465-542X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>18</Volume>
<Issue>1</Issue>
<PubDate><Year>2016</Year>
<Month>Feb</Month>
<Day>17</Day>
</PubDate>
</JournalIssue>
<Title>Breast cancer research : BCR</Title>
<ISOAbbreviation>Breast Cancer Res.</ISOAbbreviation>
</Journal>
<ArticleTitle>Genetic predisposition to ductal carcinoma in situ of the breast.</ArticleTitle>
<Pagination><MedlinePgn>22</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1186/s13058-016-0675-7</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer. It is often associated with invasive ductal carcinoma (IDC), and is considered to be a non-obligate precursor of IDC. It is not clear to what extent these two forms of cancer share low-risk susceptibility loci, or whether there are differences in the strength of association for shared loci.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">To identify genetic polymorphisms that predispose to DCIS, we pooled data from 38 studies comprising 5,067 cases of DCIS, 24,584 cases of IDC and 37,467 controls, all genotyped using the iCOGS chip.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Most (67 %) of the 76 known breast cancer predisposition loci showed an association with DCIS in the same direction as previously reported for invasive breast cancer. Case-only analysis showed no evidence for differences between associations for IDC and DCIS after considering multiple testing. Analysis by estrogen receptor (ER) status confirmed that loci associated with ER positive IDC were also associated with ER positive DCIS. Analysis of DCIS by grade suggested that two independent SNPs at 11q13.3 near CCND1 were specific to low/intermediate grade DCIS (rs75915166, rs554219). These associations with grade remained after adjusting for ER status and were also found in IDC. We found no novel DCIS-specific loci at a genome wide significance level of P < 5.0x10(-8).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">In conclusion, this study provides the strongest evidence to date of a shared genetic susceptibility for IDC and DCIS. Studies with larger numbers of DCIS are needed to determine if IDC or DCIS specific loci exist.</AbstractText>
</Abstract>
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<ForeName>Christos</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. christos.petridis@kcl.ac.uk.</Affiliation>
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<AffiliationInfo><Affiliation>Medical and Molecular Genetics, Guy's Hospital, King's College London, London, UK. christos.petridis@kcl.ac.uk.</Affiliation>
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<Initials>MN</Initials>
<AffiliationInfo><Affiliation>Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. Mark.Brook@icr.ac.uk.</Affiliation>
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<AffiliationInfo><Affiliation>K.G. Jebsen Center for Breast Cancer Research, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway. v.n.kristensen@medisin.uio.no.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, Oslo, Norway. v.n.kristensen@medisin.uio.no.</Affiliation>
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<AffiliationInfo><Affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC, Australia. Roger.Milne@cancervic.org.au.</Affiliation>
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<AffiliationInfo><Affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC, Australia. Graham.Giles@cancervic.org.au.</Affiliation>
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<AffiliationInfo><Affiliation>University of Tübingen, Tübingen, Germany. hiltrud.brauch@ikp-stuttgart.de.</Affiliation>
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<AffiliationInfo><Affiliation>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. hiltrud.brauch@ikp-stuttgart.de.</Affiliation>
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<Initials>MC</Initials>
<AffiliationInfo><Affiliation>Department of Pathology, The University of Melbourne, Melbourne, Australia. msouthey@unimelb.edu.au.</Affiliation>
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<Initials>JL</Initials>
<AffiliationInfo><Affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health, The University of Melbourne, Melbourne, VIC, Australia. j.hopper@unimelb.edu.au.</Affiliation>
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<AffiliationInfo><Affiliation>Center for Integrated Oncology (CIO), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. rita.schmutzler@uk-koeln.de.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany. rita.schmutzler@uk-koeln.de.</Affiliation>
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<Initials>A</Initials>
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<AffiliationInfo><Affiliation>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. h.brenner@dkfz.de.</Affiliation>
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<AffiliationInfo><Affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. h.brenner@dkfz.de.</Affiliation>
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<AffiliationInfo><Affiliation>Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. h.brenner@dkfz.de.</Affiliation>
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<AffiliationInfo><Affiliation>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. v.arndt@dkfz.de.</Affiliation>
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<ForeName>Robert</ForeName>
<Initials>R</Initials>
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<AffiliationInfo><Affiliation>Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu, Finland. robert.winqvist@oulu.fi.</Affiliation>
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<AffiliationInfo><Affiliation>Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu, Finland. katri.pylkas@oulu.fi.</Affiliation>
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<ForeName>Peter A</ForeName>
<Initials>PA</Initials>
<AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. peter.fasching@uk-erlangen.de.</Affiliation>
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<AffiliationInfo><Affiliation>David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA, USA. peter.fasching@uk-erlangen.de.</Affiliation>
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<Initials>MW</Initials>
<AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. Fk-direktion@uk-erlangen.de.</Affiliation>
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<ForeName>Jan</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. lubinski@pum.edu.pl.</Affiliation>
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<ForeName>Anna</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland. aniaj@pum.edu.pl.</Affiliation>
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<ForeName>Anna Marie</ForeName>
<Initials>AM</Initials>
<AffiliationInfo><Affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada. AnnaMarie.Mulligan@uhn.ca.</Affiliation>
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<AffiliationInfo><Affiliation>Laboratory Medicine Program, University Health Network, Toronto, Canada. AnnaMarie.Mulligan@uhn.ca.</Affiliation>
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<Initials>IL</Initials>
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<AffiliationInfo><Affiliation>Department of Molecular Genetics, University of Toronto, Toronto, Canada. andrulis@lunenfeld.ca.</Affiliation>
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<ForeName>Rob A E M</ForeName>
<Initials>RA</Initials>
<AffiliationInfo><Affiliation>Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands. r.a.e.m.tollenaar@lumc.nl.</Affiliation>
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<ForeName>Peter</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. p.devilee@lumc.nl.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. p.devilee@lumc.nl.</Affiliation>
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<Initials>CA</Initials>
<AffiliationInfo><Affiliation>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Christopher.Haiman@med.usc.edu.</Affiliation>
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<Initials>A</Initials>
<AffiliationInfo><Affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. arto.mannermaa@uef.fi.</Affiliation>
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<AffiliationInfo><Affiliation>Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland. arto.mannermaa@uef.fi.</Affiliation>
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<AffiliationInfo><Affiliation>Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland. arto.mannermaa@uef.fi.</Affiliation>
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<Initials>VM</Initials>
<AffiliationInfo><Affiliation>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland. veli-matti.kosma@uef.fi.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland. veli-matti.kosma@uef.fi.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland. veli-matti.kosma@uef.fi.</Affiliation>
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<Author ValidYN="Y"><LastName>Radice</LastName>
<ForeName>Paolo</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy. paolo.radice@istitutotumori.mi.it.</Affiliation>
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<Author ValidYN="Y"><LastName>Peterlongo</LastName>
<ForeName>Paolo</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>IFOM, Fondazione Istituto FIRC (Italian Foundation of Cancer Research) di Oncologia Molecolare, Milan, Italy. paolo.peterlongo@ifom.eu.</Affiliation>
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<Initials>F</Initials>
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<Initials>B</Initials>
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<AffiliationInfo><Affiliation>Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany. Barbara.Burwinkel@med.uni-heidelberg.de.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands. c.h.m.vandeurzen@erasmusmc.nl.</Affiliation>
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<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. a.hollestelle@erasmusmc.nl.</Affiliation>
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<Initials>N</Initials>
<AffiliationInfo><Affiliation>School of Medicine, National University of Ireland, Galway, Ireland. nicola.miller@nuigalway.ie.</Affiliation>
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<Initials>D</Initials>
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<Initials>J</Initials>
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<Author ValidYN="Y"><LastName>Flyger</LastName>
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<AffiliationInfo><Affiliation>Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. stig.egil.bojesen@regionh.dk.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark. stig.egil.bojesen@regionh.dk.</Affiliation>
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<AffiliationInfo><Affiliation>Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. stig.egil.bojesen@regionh.dk.</Affiliation>
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<Author ValidYN="Y"><LastName>Yao</LastName>
<ForeName>Song</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA. song.yao@roswellpark.org.</Affiliation>
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<Author ValidYN="Y"><LastName>Chenevix-Trench</LastName>
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<AffiliationInfo><Affiliation>Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia. Georgia.Trench@qimrberghofer.edu.au.</Affiliation>
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<ForeName>Thérèse</ForeName>
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<AffiliationInfo><Affiliation>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France. therese.truong@inserm.fr.</Affiliation>
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<AffiliationInfo><Affiliation>University Paris-Sud, Villejuif, France. therese.truong@inserm.fr.</Affiliation>
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<AffiliationInfo><Affiliation>University Paris-Sud, Villejuif, France. pascal.guenel@inserm.fr.</Affiliation>
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<Initials>A</Initials>
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<Initials>J</Initials>
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<Initials>H</Initials>
<AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland. Heli.Nevanlinna@hus.fi.</Affiliation>
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<Initials>C</Initials>
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<AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. kamila.czene@ki.se.</Affiliation>
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<Initials>JS</Initials>
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<Initials>JE</Initials>
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<ForeName>Fergus J</ForeName>
<Initials>FJ</Initials>
<AffiliationInfo><Affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. couch.fergus@mayo.edu.</Affiliation>
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<Initials>AM</Initials>
<AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. amd24@medschl.cam.ac.uk.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Per.Hall@ki.se.</Affiliation>
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<ForeName>Douglas F</ForeName>
<Initials>DF</Initials>
<AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. dfe20@medschl.cam.ac.uk.</Affiliation>
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<AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. dfe20@medschl.cam.ac.uk.</Affiliation>
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<ForeName>Paul D P</ForeName>
<Initials>PD</Initials>
<AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. pp10001@medschl.cam.ac.uk.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. pp10001@medschl.cam.ac.uk.</Affiliation>
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<ForeName>Sarah E</ForeName>
<Initials>SE</Initials>
<AffiliationInfo><Affiliation>Research Oncology, Guy's Hospital, King's College London, London, UK. sarah.pinder@kcl.ac.uk.</Affiliation>
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<AffiliationInfo><Affiliation>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands. mk.schmidt@nki.nl.</Affiliation>
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