Distinct immune responses of juvenile and adult oysters (Crassostrea gigas) to viral and bacterial infections.
Identifieur interne : 001C03 ( PubMed/Curation ); précédent : 001C02; suivant : 001C04Distinct immune responses of juvenile and adult oysters (Crassostrea gigas) to viral and bacterial infections.
Auteurs : Timothy J. Green [France] ; Agnes Vergnes [France] ; Caroline Montagnani [France] ; Julien De Lorgeril [France]Source :
- Veterinary research [ 1297-9716 ] ; 2016.
Descripteurs français
- KwdFr :
- Animaux, Crassostrea (génétique), Crassostrea (immunologie), Crassostrea (microbiologie), Crassostrea (virologie), Facteurs de l'âge, Herpesviridae (immunologie), Infections à Herpesviridae (immunologie), Infections à Herpesviridae (médecine vétérinaire), Infections à Herpesviridae (virologie), Infections à Vibrio (immunologie), Infections à Vibrio (microbiologie), Infections à Vibrio (médecine vétérinaire), Réaction de polymérisation en chaîne (), Vibrio (immunologie).
- MESH :
- génétique : Crassostrea.
- immunologie : Crassostrea, Herpesviridae, Infections à Herpesviridae, Infections à Vibrio, Vibrio.
- microbiologie : Crassostrea, Infections à Vibrio.
- médecine vétérinaire : Infections à Herpesviridae, Infections à Vibrio.
- virologie : Crassostrea, Infections à Herpesviridae.
- Animaux, Facteurs de l'âge, Réaction de polymérisation en chaîne.
English descriptors
- KwdEn :
- Age Factors, Animals, Crassostrea (genetics), Crassostrea (immunology), Crassostrea (microbiology), Crassostrea (virology), Herpesviridae (immunology), Herpesviridae Infections (immunology), Herpesviridae Infections (veterinary), Herpesviridae Infections (virology), Polymerase Chain Reaction (methods), Vibrio (immunology), Vibrio Infections (immunology), Vibrio Infections (microbiology), Vibrio Infections (veterinary).
- MESH :
- genetics : Crassostrea.
- immunology : Crassostrea, Herpesviridae, Herpesviridae Infections, Vibrio, Vibrio Infections.
- methods : Polymerase Chain Reaction.
- microbiology : Crassostrea, Vibrio Infections.
- veterinary : Herpesviridae Infections, Vibrio Infections.
- virology : Crassostrea, Herpesviridae Infections.
- Age Factors, Animals.
Abstract
Since 2008, massive mortality events of Pacific oysters (Crassostrea gigas) have been reported worldwide and these disease events are often associated with Ostreid herpesvirus type 1 (OsHV-1). Epidemiological field studies have also reported oyster age and other pathogens of the Vibrio genus are contributing factors to this syndrome. We undertook a controlled laboratory experiment to simultaneously investigate survival and immunological response of juvenile and adult C. gigas at different time-points post-infection with OsHV-1, Vibrio tasmaniensis LGP32 and V. aestuarianus. Our data corroborates epidemiological studies that juveniles are more susceptible to OsHV-1, whereas adults are more susceptible to Vibrio. We measured the expression of 102 immune-genes by high-throughput RT-qPCR, which revealed oysters have different transcriptional responses to OsHV-1 and Vibrio. The transcriptional response in the early stages of OsHV-1 infection involved genes related to apoptosis and the interferon-pathway. Transcriptional response to Vibrio infection involved antimicrobial peptides, heat shock proteins and galectins. Interestingly, oysters in the later stages of OsHV-1 infection had a transcriptional response that resembled an antibacterial response, which is suggestive of the oyster's microbiome causing secondary infections (dysbiosis-driven pathology). This study provides molecular evidence that oysters can mount distinct immune response to viral and bacterial pathogens and these responses differ depending on the age of the host.
DOI: 10.1186/s13567-016-0356-7
PubMed: 27439510
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001C27
Links to Exploration step
pubmed:27439510Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Distinct immune responses of juvenile and adult oysters (Crassostrea gigas) to viral and bacterial infections.</title>
<author><name sortKey="Green, Timothy J" sort="Green, Timothy J" uniqKey="Green T" first="Timothy J" last="Green">Timothy J. Green</name>
<affiliation wicri:level="1"><nlm:affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Vergnes, Agnes" sort="Vergnes, Agnes" uniqKey="Vergnes A" first="Agnes" last="Vergnes">Agnes Vergnes</name>
<affiliation wicri:level="1"><nlm:affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Montagnani, Caroline" sort="Montagnani, Caroline" uniqKey="Montagnani C" first="Caroline" last="Montagnani">Caroline Montagnani</name>
<affiliation wicri:level="1"><nlm:affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France. cmontagn@ifremer.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Lorgeril, Julien" sort="De Lorgeril, Julien" uniqKey="De Lorgeril J" first="Julien" last="De Lorgeril">Julien De Lorgeril</name>
<affiliation wicri:level="1"><nlm:affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:27439510</idno>
<idno type="pmid">27439510</idno>
<idno type="doi">10.1186/s13567-016-0356-7</idno>
<idno type="wicri:Area/PubMed/Corpus">001C27</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001C27</idno>
<idno type="wicri:Area/PubMed/Curation">001C03</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001C03</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Distinct immune responses of juvenile and adult oysters (Crassostrea gigas) to viral and bacterial infections.</title>
<author><name sortKey="Green, Timothy J" sort="Green, Timothy J" uniqKey="Green T" first="Timothy J" last="Green">Timothy J. Green</name>
<affiliation wicri:level="1"><nlm:affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Vergnes, Agnes" sort="Vergnes, Agnes" uniqKey="Vergnes A" first="Agnes" last="Vergnes">Agnes Vergnes</name>
<affiliation wicri:level="1"><nlm:affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Montagnani, Caroline" sort="Montagnani, Caroline" uniqKey="Montagnani C" first="Caroline" last="Montagnani">Caroline Montagnani</name>
<affiliation wicri:level="1"><nlm:affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France. cmontagn@ifremer.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Lorgeril, Julien" sort="De Lorgeril, Julien" uniqKey="De Lorgeril J" first="Julien" last="De Lorgeril">Julien De Lorgeril</name>
<affiliation wicri:level="1"><nlm:affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Veterinary research</title>
<idno type="eISSN">1297-9716</idno>
<imprint><date when="2016" type="published">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age Factors</term>
<term>Animals</term>
<term>Crassostrea (genetics)</term>
<term>Crassostrea (immunology)</term>
<term>Crassostrea (microbiology)</term>
<term>Crassostrea (virology)</term>
<term>Herpesviridae (immunology)</term>
<term>Herpesviridae Infections (immunology)</term>
<term>Herpesviridae Infections (veterinary)</term>
<term>Herpesviridae Infections (virology)</term>
<term>Polymerase Chain Reaction (methods)</term>
<term>Vibrio (immunology)</term>
<term>Vibrio Infections (immunology)</term>
<term>Vibrio Infections (microbiology)</term>
<term>Vibrio Infections (veterinary)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Crassostrea (génétique)</term>
<term>Crassostrea (immunologie)</term>
<term>Crassostrea (microbiologie)</term>
<term>Crassostrea (virologie)</term>
<term>Facteurs de l'âge</term>
<term>Herpesviridae (immunologie)</term>
<term>Infections à Herpesviridae (immunologie)</term>
<term>Infections à Herpesviridae (médecine vétérinaire)</term>
<term>Infections à Herpesviridae (virologie)</term>
<term>Infections à Vibrio (immunologie)</term>
<term>Infections à Vibrio (microbiologie)</term>
<term>Infections à Vibrio (médecine vétérinaire)</term>
<term>Réaction de polymérisation en chaîne ()</term>
<term>Vibrio (immunologie)</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Crassostrea</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Crassostrea</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Crassostrea</term>
<term>Herpesviridae</term>
<term>Infections à Herpesviridae</term>
<term>Infections à Vibrio</term>
<term>Vibrio</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Crassostrea</term>
<term>Herpesviridae</term>
<term>Herpesviridae Infections</term>
<term>Vibrio</term>
<term>Vibrio Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Polymerase Chain Reaction</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Crassostrea</term>
<term>Infections à Vibrio</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Crassostrea</term>
<term>Vibrio Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Infections à Herpesviridae</term>
<term>Infections à Vibrio</term>
</keywords>
<keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Herpesviridae Infections</term>
<term>Vibrio Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Crassostrea</term>
<term>Infections à Herpesviridae</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Crassostrea</term>
<term>Herpesviridae Infections</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Age Factors</term>
<term>Animals</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Facteurs de l'âge</term>
<term>Réaction de polymérisation en chaîne</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Since 2008, massive mortality events of Pacific oysters (Crassostrea gigas) have been reported worldwide and these disease events are often associated with Ostreid herpesvirus type 1 (OsHV-1). Epidemiological field studies have also reported oyster age and other pathogens of the Vibrio genus are contributing factors to this syndrome. We undertook a controlled laboratory experiment to simultaneously investigate survival and immunological response of juvenile and adult C. gigas at different time-points post-infection with OsHV-1, Vibrio tasmaniensis LGP32 and V. aestuarianus. Our data corroborates epidemiological studies that juveniles are more susceptible to OsHV-1, whereas adults are more susceptible to Vibrio. We measured the expression of 102 immune-genes by high-throughput RT-qPCR, which revealed oysters have different transcriptional responses to OsHV-1 and Vibrio. The transcriptional response in the early stages of OsHV-1 infection involved genes related to apoptosis and the interferon-pathway. Transcriptional response to Vibrio infection involved antimicrobial peptides, heat shock proteins and galectins. Interestingly, oysters in the later stages of OsHV-1 infection had a transcriptional response that resembled an antibacterial response, which is suggestive of the oyster's microbiome causing secondary infections (dysbiosis-driven pathology). This study provides molecular evidence that oysters can mount distinct immune response to viral and bacterial pathogens and these responses differ depending on the age of the host.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27439510</PMID>
<DateCreated><Year>2016</Year>
<Month>07</Month>
<Day>21</Day>
</DateCreated>
<DateCompleted><Year>2017</Year>
<Month>09</Month>
<Day>26</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>09</Month>
<Day>26</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1297-9716</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>47</Volume>
<Issue>1</Issue>
<PubDate><Year>2016</Year>
<Month>Jul</Month>
<Day>21</Day>
</PubDate>
</JournalIssue>
<Title>Veterinary research</Title>
<ISOAbbreviation>Vet. Res.</ISOAbbreviation>
</Journal>
<ArticleTitle>Distinct immune responses of juvenile and adult oysters (Crassostrea gigas) to viral and bacterial infections.</ArticleTitle>
<Pagination><MedlinePgn>72</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1186/s13567-016-0356-7</ELocationID>
<Abstract><AbstractText>Since 2008, massive mortality events of Pacific oysters (Crassostrea gigas) have been reported worldwide and these disease events are often associated with Ostreid herpesvirus type 1 (OsHV-1). Epidemiological field studies have also reported oyster age and other pathogens of the Vibrio genus are contributing factors to this syndrome. We undertook a controlled laboratory experiment to simultaneously investigate survival and immunological response of juvenile and adult C. gigas at different time-points post-infection with OsHV-1, Vibrio tasmaniensis LGP32 and V. aestuarianus. Our data corroborates epidemiological studies that juveniles are more susceptible to OsHV-1, whereas adults are more susceptible to Vibrio. We measured the expression of 102 immune-genes by high-throughput RT-qPCR, which revealed oysters have different transcriptional responses to OsHV-1 and Vibrio. The transcriptional response in the early stages of OsHV-1 infection involved genes related to apoptosis and the interferon-pathway. Transcriptional response to Vibrio infection involved antimicrobial peptides, heat shock proteins and galectins. Interestingly, oysters in the later stages of OsHV-1 infection had a transcriptional response that resembled an antibacterial response, which is suggestive of the oyster's microbiome causing secondary infections (dysbiosis-driven pathology). This study provides molecular evidence that oysters can mount distinct immune response to viral and bacterial pathogens and these responses differ depending on the age of the host.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Green</LastName>
<ForeName>Timothy J</ForeName>
<Initials>TJ</Initials>
<AffiliationInfo><Affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Biological Sciences, Macquarie University, Sydney, NSW, 2109, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vergnes</LastName>
<ForeName>Agnes</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Montagnani</LastName>
<ForeName>Caroline</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France. cmontagn@ifremer.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>de Lorgeril</LastName>
<ForeName>Julien</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>IFREMER, IHPE, UMR 5244, Univ. Perpignan Via Domitia, CNRS, Univ. Montpellier, 34095, Montpellier, France.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2016</Year>
<Month>07</Month>
<Day>21</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Vet Res</MedlineTA>
<NlmUniqueID>9309551</NlmUniqueID>
<ISSNLinking>0928-4249</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Environ Microbiol. 2015 Nov;17(11):4200-12</RefSource>
<PMID Version="1">25384719</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Environ Microbiol. 2010 Apr;12(4):951-63</RefSource>
<PMID Version="1">20074236</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Appl Microbiol. 2006 Apr;100(4):664-72</RefSource>
<PMID Version="1">16553721</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Appl Microbiol. 2010 Aug;109(2):613-22</RefSource>
<PMID Version="1">20202017</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Vet Res. 2014 Oct 08;45:103</RefSource>
<PMID Version="1">25294338</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Curr Opin Virol. 2011 Dec;1(6):519-25</RefSource>
<PMID Version="1">22328912</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nat Immunol. 2011 Jul 19;12(8):695-708</RefSource>
<PMID Version="1">21772278</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Biol Chem. 2008 Oct;389(10):1307-12</RefSource>
<PMID Version="1">18713017</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Invertebr Pathol. 2015 Oct;131:11-31</RefSource>
<PMID Version="1">26210496</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Methods. 2001 Dec;25(4):402-8</RefSource>
<PMID Version="1">11846609</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Dis Aquat Organ. 2013 Jul 22;105(2):109-26</RefSource>
<PMID Version="1">23872855</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Gen Virol. 2008 Jan;89(Pt 1):1-47</RefSource>
<PMID Version="1">18089727</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Virol Methods. 2008 May;149(2):269-76</RefSource>
<PMID Version="1">18342377</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Fish Shellfish Immunol. 2015 Sep;46(1):131-44</RefSource>
<PMID Version="1">26004318</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Invertebr Pathol. 2014 Jun;119:5-11</RefSource>
<PMID Version="1">24681357</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann N Y Acad Sci. 2003 Dec;1010:237-48</RefSource>
<PMID Version="1">15033728</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2011;6(8):e23142</RefSource>
<PMID Version="1">21829707</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Front Microbiol. 2015 Jul 06;6:686</RefSource>
<PMID Version="1">26217318</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Oncogene. 1999 Nov 1;18(45):6163-71</RefSource>
<PMID Version="1">10557108</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>BMC Genomics. 2014 Jul 09;15:580</RefSource>
<PMID Version="1">25012085</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Gen Virol. 2015 Sep;96(9):2471-82</RefSource>
<PMID Version="1">26297577</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Vet Res. 2011 Jun 02;42:73</RefSource>
<PMID Version="1">21635731</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Virus Res. 2010 Oct;153(1):92-9</RefSource>
<PMID Version="1">20638433</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Microb Ecol. 2007 Feb;53(2):187-96</RefSource>
<PMID Version="1">17245611</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nature. 2012 Oct 4;490(7418):49-54</RefSource>
<PMID Version="1">22992520</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mol Ecol. 2011 Jul;20(14):2942-54</RefSource>
<PMID Version="1">21672066</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Vet Res. 2015 Dec 09;46:139</RefSource>
<PMID Version="1">26646058</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Gene. 2007 Dec 30;406(1-2):13-22</RefSource>
<PMID Version="1">17616269</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Microbiol Methods. 2009 May;77(2):191-7</RefSource>
<PMID Version="1">19318049</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Invertebr Pathol. 2015 Oct;131:2-10</RefSource>
<PMID Version="1">26210497</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Virus Res. 2011 Sep;160(1-2):25-31</RefSource>
<PMID Version="1">21600247</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Vet Res. 2011 Feb 07;42:27</RefSource>
<PMID Version="1">21314910</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>BMC Genomics. 2012 Jun 18;13:252</RefSource>
<PMID Version="1">22708697</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Dev Comp Immunol. 2011 Jul;35(7):725-35</RefSource>
<PMID Version="1">21371503</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Immunity. 2014 Mar 20;40(3):342-54</RefSource>
<PMID Version="1">24656046</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Prev Vet Med. 2012 Jun 1;105(1-2):136-43</RefSource>
<PMID Version="1">22398251</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Fish Shellfish Immunol. 2013 Aug;35(2):382-8</RefSource>
<PMID Version="1">23685009</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Physiol Regul Integr Comp Physiol. 2007 Dec;293(6):R2353-62</RefSource>
<PMID Version="1">17898119</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Annu Rev Immunol. 2014;32:513-45</RefSource>
<PMID Version="1">24555472</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nat Rev Immunol. 2007 Oct;7(10):753-66</RefSource>
<PMID Version="1">17893693</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Fish Shellfish Immunol. 2014 Nov;41(1):37-44</RefSource>
<PMID Version="1">24909498</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>BMC Genomics. 2009 Jul 29;10:341</RefSource>
<PMID Version="1">19640306</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mar Genomics. 2014 Jun;15:95-102</RefSource>
<PMID Version="1">24582708</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Sci Rep. 2015 Mar 03;5:8693</RefSource>
<PMID Version="1">25732911</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Dis Aquat Organ. 2014 Jul 3;109(3):231-9</RefSource>
<PMID Version="1">24991849</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Dis Aquat Organ. 2004 Nov 23;62(1-2):65-74</RefSource>
<PMID Version="1">15648832</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Genes Dev. 2004 Sep 15;18(18):2195-224</RefSource>
<PMID Version="1">15371334</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000367" MajorTopicYN="N">Age Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D049896" MajorTopicYN="N">Crassostrea</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006564" MajorTopicYN="N">Herpesviridae</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006566" MajorTopicYN="N">Herpesviridae Infections</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000662" MajorTopicYN="N">veterinary</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016133" MajorTopicYN="N">Polymerase Chain Reaction</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014733" MajorTopicYN="N">Vibrio</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014735" MajorTopicYN="N">Vibrio Infections</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
<QualifierName UI="Q000662" MajorTopicYN="N">veterinary</QualifierName>
</MeshHeading>
</MeshHeadingList>
<OtherID Source="NLM">PMC4955271</OtherID>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year>
<Month>01</Month>
<Day>27</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2016</Year>
<Month>05</Month>
<Day>02</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2016</Year>
<Month>7</Month>
<Day>22</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2016</Year>
<Month>7</Month>
<Day>22</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2017</Year>
<Month>9</Month>
<Day>28</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">27439510</ArticleId>
<ArticleId IdType="doi">10.1186/s13567-016-0356-7</ArticleId>
<ArticleId IdType="pii">10.1186/s13567-016-0356-7</ArticleId>
<ArticleId IdType="pmc">PMC4955271</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001C03 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 001C03 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Asie |area= AustralieFrV1 |flux= PubMed |étape= Curation |type= RBID |clé= pubmed:27439510 |texte= Distinct immune responses of juvenile and adult oysters (Crassostrea gigas) to viral and bacterial infections. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:27439510" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \ | NlmPubMed2Wicri -a AustralieFrV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |