The impact of level of education on vascular events and mortality in patients with type 2 diabetes mellitus: Results from the ADVANCE study.
Identifieur interne : 000C21 ( PubMed/Curation ); précédent : 000C20; suivant : 000C22The impact of level of education on vascular events and mortality in patients with type 2 diabetes mellitus: Results from the ADVANCE study.
Auteurs : J I Blomster [Finlande] ; S. Zoungas [Australie] ; M. Woodward [Royaume-Uni] ; B. Neal [Australie] ; S. Harrap [Australie] ; N. Poulter [Royaume-Uni] ; M. Marre [France] ; B. Williams [Royaume-Uni] ; J. Chalmers [Australie] ; G S Hillis [Australie]Source :
- Diabetes research and clinical practice [ 1872-8227 ] ; 2017.
Abstract
The relationship between educational level and the risk of all-cause mortality is well established, whereas the association with vascular events in individuals with type 2 diabetes is not well described. Any association may reflect a link with common cardiovascular or lifestyle-based risk factors.
DOI: 10.1016/j.diabres.2017.03.015
PubMed: 28395214
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Electronic address: jmakinen@georgeinstitute.org.au.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>The George Institute for Global Health, University of Sydney, Sydney, Australia; University of Turku, Turku</wicri:regionArea></affiliation></author><author><name sortKey="Zoungas, S" sort="Zoungas, S" uniqKey="Zoungas S" first="S" last="Zoungas">S. Zoungas</name><affiliation wicri:level="1"><nlm:affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia; School of Public Health, Monash University, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The George Institute for Global Health, University of Sydney, Sydney, Australia; School of Public Health, Monash University, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Woodward, M" sort="Woodward, M" uniqKey="Woodward M" first="M" last="Woodward">M. Woodward</name><affiliation wicri:level="1"><nlm:affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia; Department of Epidemiology, Johns Hopkins University, Baltimore, USA; The George Institute for Global Health, University of Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The George Institute for Global Health, University of Sydney, Sydney, Australia; Department of Epidemiology, Johns Hopkins University, Baltimore, USA; The George Institute for Global Health, University of Oxford</wicri:regionArea></affiliation></author><author><name sortKey="Neal, B" sort="Neal, B" uniqKey="Neal B" first="B" last="Neal">B. Neal</name><affiliation wicri:level="1"><nlm:affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The George Institute for Global Health, University of Sydney, Sydney</wicri:regionArea></affiliation></author><author><name sortKey="Harrap, S" sort="Harrap, S" uniqKey="Harrap S" first="S" last="Harrap">S. Harrap</name><affiliation wicri:level="1"><nlm:affiliation>Department of Physiology, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Physiology, University of Melbourne and Royal Melbourne Hospital, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Poulter, N" sort="Poulter, N" uniqKey="Poulter N" first="N" last="Poulter">N. Poulter</name><affiliation wicri:level="1"><nlm:affiliation>Imperial College London and Hammersmith Hospital, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Imperial College London and Hammersmith Hospital, London</wicri:regionArea></affiliation></author><author><name sortKey="Marre, M" sort="Marre, M" uniqKey="Marre M" first="M" last="Marre">M. Marre</name><affiliation wicri:level="1"><nlm:affiliation>Service d'Endocrinologie Diabétologie Nutrition, Groupe Hospitalier Bichat-Claude Bernard, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service d'Endocrinologie Diabétologie Nutrition, Groupe Hospitalier Bichat-Claude Bernard, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Williams, B" sort="Williams, B" uniqKey="Williams B" first="B" last="Williams">B. Williams</name><affiliation wicri:level="1"><nlm:affiliation>University College London and the National Institute for Health Research UCL Hospitals Biomedical Research Centre, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University College London and the National Institute for Health Research UCL Hospitals Biomedical Research Centre, London</wicri:regionArea></affiliation></author><author><name sortKey="Chalmers, J" sort="Chalmers, J" uniqKey="Chalmers J" first="J" last="Chalmers">J. Chalmers</name><affiliation wicri:level="1"><nlm:affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The George Institute for Global Health, University of Sydney, Sydney</wicri:regionArea></affiliation></author><author><name sortKey="Hillis, G S" sort="Hillis, G S" uniqKey="Hillis G" first="G S" last="Hillis">G S Hillis</name><affiliation wicri:level="1"><nlm:affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia; Department of Cardiology, Royal Perth Hospital, Perth, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The George Institute for Global Health, University of Sydney, Sydney, Australia; Department of Cardiology, Royal Perth Hospital, Perth</wicri:regionArea></affiliation></author></analytic><series><title level="j">Diabetes research and clinical practice</title><idno type="eISSN">1872-8227</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The relationship between educational level and the risk of all-cause mortality is well established, whereas the association with vascular events in individuals with type 2 diabetes is not well described. Any association may reflect a link with common cardiovascular or lifestyle-based risk factors.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28395214</PMID><DateCreated><Year>2017</Year><Month>04</Month><Day>10</Day></DateCreated><DateRevised><Year>2017</Year><Month>05</Month><Day>12</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1872-8227</ISSN><JournalIssue CitedMedium="Internet"><Volume>127</Volume><PubDate><Year>2017</Year><Month>May</Month></PubDate></JournalIssue><Title>Diabetes research and clinical practice</Title><ISOAbbreviation>Diabetes Res. Clin. Pract.</ISOAbbreviation></Journal><ArticleTitle>The impact of level of education on vascular events and mortality in patients with type 2 diabetes mellitus: Results from the ADVANCE study.</ArticleTitle><Pagination><MedlinePgn>212-217</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0168-8227(16)30529-0</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.diabres.2017.03.015</ELocationID><Abstract><AbstractText Label="AIMS" NlmCategory="OBJECTIVE">The relationship between educational level and the risk of all-cause mortality is well established, whereas the association with vascular events in individuals with type 2 diabetes is not well described. Any association may reflect a link with common cardiovascular or lifestyle-based risk factors.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The relationships between the highest level of educational attainment and major cardiovascular events, microvascular complications and all-cause mortality were explored in a cohort of 11,140 individuals with type 2 diabetes. Completion of formal education before the age of 16 was categorized as a low level of education. Regional differences between Asia, East Europe and Established Market Economies were also assessed.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">During a median of 5years of follow up, 1031 (9%) patients died, 1147 (10%) experienced a major cardiovascular event and 1136 (10%) a microvascular event. After adjustment for baseline characteristics and risk factors, individuals with lower education had an increased risk of cardiovascular events (hazard ratio (HR) 1.31, 95% CI 1.16-1.48, p<0.0001), microvascular events (HR 1.23, 95% CI 1.08-1.39, p=0.0013) and all-cause mortality (HR 1.34, 95% CI 1.18-1.52, p<0.0001). In regional analyses the increased risk of studied outcomes associated with lower education was weakest in Established Market Economies and strongest in East Europe.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">A low level of education is associated with an increased risk of vascular events and death in patients with type 2 diabetes, independently of common lifestyle associated cardiovascular risk factors. The effect size varies between geographical regions.</AbstractText><CopyrightInformation>Copyright © 2017. Published by Elsevier B.V.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Blomster</LastName><ForeName>J I</ForeName><Initials>JI</Initials><AffiliationInfo><Affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia; University of Turku, Turku, Finland. Electronic address: jmakinen@georgeinstitute.org.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zoungas</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia; School of Public Health, Monash University, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Woodward</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia; Department of Epidemiology, Johns Hopkins University, Baltimore, USA; The George Institute for Global Health, University of Oxford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Neal</LastName><ForeName>B</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Harrap</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Physiology, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Poulter</LastName><ForeName>N</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Imperial College London and Hammersmith Hospital, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marre</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Service d'Endocrinologie Diabétologie Nutrition, Groupe Hospitalier Bichat-Claude Bernard, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Williams</LastName><ForeName>B</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>University College London and the National Institute for Health Research UCL Hospitals Biomedical Research Centre, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chalmers</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hillis</LastName><ForeName>G S</ForeName><Initials>GS</Initials><AffiliationInfo><Affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia; Department of Cardiology, Royal Perth Hospital, Perth, Australia.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>03</Month><Day>21</Day></ArticleDate></Article><MedlineJournalInfo><Country>Ireland</Country><MedlineTA>Diabetes Res Clin Pract</MedlineTA><NlmUniqueID>8508335</NlmUniqueID><ISSNLinking>0168-8227</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Cardiovascular events</Keyword><Keyword MajorTopicYN="N">Level of education</Keyword><Keyword MajorTopicYN="N">Microvascular events</Keyword><Keyword MajorTopicYN="N">Type 2 diabetes</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>11</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>03</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>4</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>4</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>4</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28395214</ArticleId><ArticleId IdType="pii">S0168-8227(16)30529-0</ArticleId><ArticleId IdType="doi">10.1016/j.diabres.2017.03.015</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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