The impact of level of education on vascular events and mortality in patients with type 2 diabetes mellitus: Results from the ADVANCE study.
Identifieur interne : 000C24 ( PubMed/Corpus ); précédent : 000C23; suivant : 000C25The impact of level of education on vascular events and mortality in patients with type 2 diabetes mellitus: Results from the ADVANCE study.
Auteurs : J I Blomster ; S. Zoungas ; M. Woodward ; B. Neal ; S. Harrap ; N. Poulter ; M. Marre ; B. Williams ; J. Chalmers ; G S HillisSource :
- Diabetes research and clinical practice [ 1872-8227 ] ; 2017.
Abstract
The relationship between educational level and the risk of all-cause mortality is well established, whereas the association with vascular events in individuals with type 2 diabetes is not well described. Any association may reflect a link with common cardiovascular or lifestyle-based risk factors.
DOI: 10.1016/j.diabres.2017.03.015
PubMed: 28395214
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pubmed:28395214Le document en format XML
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<series><title level="j">Diabetes research and clinical practice</title>
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<front><div type="abstract" xml:lang="en">The relationship between educational level and the risk of all-cause mortality is well established, whereas the association with vascular events in individuals with type 2 diabetes is not well described. Any association may reflect a link with common cardiovascular or lifestyle-based risk factors.</div>
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<pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28395214</PMID>
<DateCreated><Year>2017</Year>
<Month>04</Month>
<Day>10</Day>
</DateCreated>
<DateRevised><Year>2017</Year>
<Month>05</Month>
<Day>12</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1872-8227</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>127</Volume>
<PubDate><Year>2017</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>Diabetes research and clinical practice</Title>
<ISOAbbreviation>Diabetes Res. Clin. Pract.</ISOAbbreviation>
</Journal>
<ArticleTitle>The impact of level of education on vascular events and mortality in patients with type 2 diabetes mellitus: Results from the ADVANCE study.</ArticleTitle>
<Pagination><MedlinePgn>212-217</MedlinePgn>
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<Abstract><AbstractText Label="AIMS" NlmCategory="OBJECTIVE">The relationship between educational level and the risk of all-cause mortality is well established, whereas the association with vascular events in individuals with type 2 diabetes is not well described. Any association may reflect a link with common cardiovascular or lifestyle-based risk factors.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The relationships between the highest level of educational attainment and major cardiovascular events, microvascular complications and all-cause mortality were explored in a cohort of 11,140 individuals with type 2 diabetes. Completion of formal education before the age of 16 was categorized as a low level of education. Regional differences between Asia, East Europe and Established Market Economies were also assessed.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">During a median of 5years of follow up, 1031 (9%) patients died, 1147 (10%) experienced a major cardiovascular event and 1136 (10%) a microvascular event. After adjustment for baseline characteristics and risk factors, individuals with lower education had an increased risk of cardiovascular events (hazard ratio (HR) 1.31, 95% CI 1.16-1.48, p<0.0001), microvascular events (HR 1.23, 95% CI 1.08-1.39, p=0.0013) and all-cause mortality (HR 1.34, 95% CI 1.18-1.52, p<0.0001). In regional analyses the increased risk of studied outcomes associated with lower education was weakest in Established Market Economies and strongest in East Europe.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">A low level of education is associated with an increased risk of vascular events and death in patients with type 2 diabetes, independently of common lifestyle associated cardiovascular risk factors. The effect size varies between geographical regions.</AbstractText>
<CopyrightInformation>Copyright © 2017. Published by Elsevier B.V.</CopyrightInformation>
</Abstract>
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<ForeName>J I</ForeName>
<Initials>JI</Initials>
<AffiliationInfo><Affiliation>The George Institute for Global Health, University of Sydney, Sydney, Australia; University of Turku, Turku, Finland. Electronic address: jmakinen@georgeinstitute.org.au.</Affiliation>
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<Initials>B</Initials>
<AffiliationInfo><Affiliation>University College London and the National Institute for Health Research UCL Hospitals Biomedical Research Centre, London, UK.</Affiliation>
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<MedlineTA>Diabetes Res Clin Pract</MedlineTA>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Cardiovascular events</Keyword>
<Keyword MajorTopicYN="N">Level of education</Keyword>
<Keyword MajorTopicYN="N">Microvascular events</Keyword>
<Keyword MajorTopicYN="N">Type 2 diabetes</Keyword>
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