Rationale, Design and Baseline Characteristics of Participants in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) Trial.
Identifieur interne : 000806 ( PubMed/Curation ); précédent : 000805; suivant : 000807Rationale, Design and Baseline Characteristics of Participants in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) Trial.
Auteurs : Jackie Bosch [Canada] ; John W. Eikelboom [Canada] ; Stuart J. Connolly [Canada] ; Nancy Cook Bruns [Allemagne] ; Vivian Lanius [Allemagne] ; Fei Yuan [Canada] ; Frank Misselwitz [Allemagne] ; Edmond Chen [Allemagne] ; Rafael Diaz [Argentine] ; Marco Alings [Pays-Bas] ; Eva M. Lonn [Canada] ; Petr Widimsky [République tchèque] ; Masatsugu Hori [Japon] ; Alvaro Avezum [Brésil] ; Leopoldo S. Piegas [Brésil] ; Deepak L. Bhatt [États-Unis] ; Kelley R H. Branch [États-Unis] ; Jeffrey L. Probstfield [États-Unis] ; Yan Liang [République populaire de Chine] ; Lisheng Liu [République populaire de Chine] ; Jun Zhu [République populaire de Chine] ; Aldo P. Maggioni [Italie] ; Patricio Lopez-Jaramillo [Colombie] ; Martin O'Donnell [Irlande (pays)] ; Keith A A. Fox [Royaume-Uni] ; Ajay Kakkar [Royaume-Uni] ; Alexander N. Parkhomenko [Ukraine] ; Georg Ertl [Allemagne] ; Stefan Störk [Allemagne] ; Katalin Keltai [Hongrie] ; Matyas Keltai [Hongrie] ; Lars Ryden [Suède] ; Gilles R. Dagenais [Canada] ; Nana Pogosova [Russie] ; Antonio L. Dans ; Fernando Lanas [Chili] ; Patrick J. Commerford [Chili] ; Christian Torp-Pedersen [Danemark] ; Tomasz J. Guzik [Royaume-Uni] ; Peter B. Verhamme [Belgique] ; Dragos Vinereanu [Roumanie] ; Jae-Hyung Kim [Corée du Sud] ; Jong-Won Ha [Corée du Sud] ; Andrew M. Tonkin [Australie] ; John D. Varigos [Australie] ; Basil S. Lewis [Israël] ; Camilo Felix [Équateur] ; Khalid Yusoff [Malaisie] ; Philippe Gabriel Steg [France] ; Victor Aboyans [France] ; Kaj P. Metsarinne [Finlande] ; Sonia S. Anand [Canada] ; Robert G. Hart [Canada] ; Andre Lamy [Canada] ; Paul Moayyedi [Canada] ; Darryl P. Leong [Canada] ; Mukul Sharma [Canada] ; Salim Yusuf [Canada]Source :
- The Canadian journal of cardiology [ 1916-7075 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
- normes : Traitement thrombolytique.
- usage thérapeutique : Anticoagulants.
- Essais contrôlés randomisés comme sujet, Guides de bonnes pratiques cliniques comme sujet, Humains, Maladies cardiovasculaires.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Anticoagulants.
- methods : Randomized Controlled Trials as Topic.
- prevention & control : Cardiovascular Diseases.
- standards : Thrombolytic Therapy.
- Humans, Practice Guidelines as Topic.
Abstract
Long-term aspirin prevents vascular events but is only modestly effective. Rivaroxaban alone or in combination with aspirin might be more effective than aspirin alone for vascular prevention in patients with stable coronary artery disease (CAD) or peripheral artery disease (PAD). Rivaroxaban as well as aspirin increase upper gastrointestinal (GI) bleeding and this might be prevented by proton pump inhibitor therapy.
DOI: 10.1016/j.cjca.2017.06.001
PubMed: 28754388
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Antonio L. Dans<affiliation><nlm:affiliation>University of Philippines - Manila, Manila, The Philippines.</nlm:affiliation><wicri:noCountry code="subField">The Philippines</wicri:noCountry></affiliation>Le document en format XML
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Piegas</name><affiliation wicri:level="1"><nlm:affiliation>University of Sao Paulo, Sao Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>University of Sao Paulo, Sao Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Bhatt, Deepak L" sort="Bhatt, Deepak L" uniqKey="Bhatt D" first="Deepak L" last="Bhatt">Deepak L. Bhatt</name><affiliation wicri:level="1"><nlm:affiliation>Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Branch, Kelley R H" sort="Branch, Kelley R H" uniqKey="Branch K" first="Kelley R H" last="Branch">Kelley R H. Branch</name><affiliation wicri:level="1"><nlm:affiliation>University of Washington Medical Centre, Seattle, Washington, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Washington Medical Centre, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Probstfield, Jeffrey L" sort="Probstfield, Jeffrey L" uniqKey="Probstfield J" first="Jeffrey L" last="Probstfield">Jeffrey L. Probstfield</name><affiliation wicri:level="1"><nlm:affiliation>University of Washington, Seattle, Washington, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Washington, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Liang, Yan" sort="Liang, Yan" uniqKey="Liang Y" first="Yan" last="Liang">Yan Liang</name><affiliation wicri:level="1"><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>FuWai Hospital, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Lisheng" sort="Liu, Lisheng" uniqKey="Liu L" first="Lisheng" last="Liu">Lisheng Liu</name><affiliation wicri:level="1"><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>FuWai Hospital, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Zhu, Jun" sort="Zhu, Jun" uniqKey="Zhu J" first="Jun" last="Zhu">Jun Zhu</name><affiliation wicri:level="1"><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>FuWai Hospital, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Maggioni, Aldo P" sort="Maggioni, Aldo P" uniqKey="Maggioni A" first="Aldo P" last="Maggioni">Aldo P. Maggioni</name><affiliation wicri:level="1"><nlm:affiliation>ANMCO Research Center, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>ANMCO Research Center, Florence</wicri:regionArea></affiliation></author><author><name sortKey="Lopez Jaramillo, Patricio" sort="Lopez Jaramillo, Patricio" uniqKey="Lopez Jaramillo P" first="Patricio" last="Lopez-Jaramillo">Patricio Lopez-Jaramillo</name><affiliation wicri:level="1"><nlm:affiliation>Research Institute, FOSCAL-Bucaramanga, Bucaramanga, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Research Institute, FOSCAL-Bucaramanga, Bucaramanga</wicri:regionArea></affiliation></author><author><name sortKey="O Donnell, Martin" sort="O Donnell, Martin" uniqKey="O Donnell M" first="Martin" last="O'Donnell">Martin O'Donnell</name><affiliation wicri:level="1"><nlm:affiliation>National University of Ireland, Galway, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>National University of Ireland, Galway</wicri:regionArea></affiliation></author><author><name sortKey="Fox, Keith A A" sort="Fox, Keith A A" uniqKey="Fox K" first="Keith A A" last="Fox">Keith A A. Fox</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Centre for Cardiovascular Science, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Kakkar, Ajay" sort="Kakkar, Ajay" uniqKey="Kakkar A" first="Ajay" last="Kakkar">Ajay Kakkar</name><affiliation wicri:level="1"><nlm:affiliation>University College London Hospitals, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University College London Hospitals, London</wicri:regionArea></affiliation></author><author><name sortKey="Parkhomenko, Alexander N" sort="Parkhomenko, Alexander N" uniqKey="Parkhomenko A" first="Alexander N" last="Parkhomenko">Alexander N. Parkhomenko</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology (Ukraine), Kiev, Ukraine.</nlm:affiliation><country xml:lang="fr">Ukraine</country><wicri:regionArea>Institute of Cardiology (Ukraine), Kiev</wicri:regionArea></affiliation></author><author><name sortKey="Ertl, Georg" sort="Ertl, Georg" uniqKey="Ertl G" first="Georg" last="Ertl">Georg Ertl</name><affiliation wicri:level="1"><nlm:affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg</wicri:regionArea></affiliation></author><author><name sortKey="Stork, Stefan" sort="Stork, Stefan" uniqKey="Stork S" first="Stefan" last="Störk">Stefan Störk</name><affiliation wicri:level="1"><nlm:affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg</wicri:regionArea></affiliation></author><author><name sortKey="Keltai, Katalin" sort="Keltai, Katalin" uniqKey="Keltai K" first="Katalin" last="Keltai">Katalin Keltai</name><affiliation wicri:level="1"><nlm:affiliation>Semmelweis University, Budapest, Hungary.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Semmelweis University, Budapest</wicri:regionArea></affiliation></author><author><name sortKey="Keltai, Matyas" sort="Keltai, Matyas" uniqKey="Keltai M" first="Matyas" last="Keltai">Matyas Keltai</name><affiliation wicri:level="1"><nlm:affiliation>Semmelweis University, Budapest, Hungary.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Semmelweis University, Budapest</wicri:regionArea></affiliation></author><author><name sortKey="Ryden, Lars" sort="Ryden, Lars" uniqKey="Ryden L" first="Lars" last="Ryden">Lars Ryden</name><affiliation wicri:level="1"><nlm:affiliation>Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Dagenais, Gilles R" sort="Dagenais, Gilles R" uniqKey="Dagenais G" first="Gilles R" last="Dagenais">Gilles R. Dagenais</name><affiliation wicri:level="1"><nlm:affiliation>Institut Universitaire de Cardiologie et Pneumologie de Quebec, Quebec City, Quebec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Institut Universitaire de Cardiologie et Pneumologie de Quebec, Quebec City, Quebec</wicri:regionArea></affiliation></author><author><name sortKey="Pogosova, Nana" sort="Pogosova, Nana" uniqKey="Pogosova N" first="Nana" last="Pogosova">Nana Pogosova</name><affiliation wicri:level="1"><nlm:affiliation>National Research Centre for Preventative Medicine (Moscow), Moscow, Russia.</nlm:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>National Research Centre for Preventative Medicine (Moscow), Moscow</wicri:regionArea></affiliation></author><author><name sortKey="Dans, Antonio L" sort="Dans, Antonio L" uniqKey="Dans A" first="Antonio L" last="Dans">Antonio L. Dans</name><affiliation><nlm:affiliation>University of Philippines - Manila, Manila, The Philippines.</nlm:affiliation><wicri:noCountry code="subField">The Philippines</wicri:noCountry></affiliation></author><author><name sortKey="Lanas, Fernando" sort="Lanas, Fernando" uniqKey="Lanas F" first="Fernando" last="Lanas">Fernando Lanas</name><affiliation wicri:level="1"><nlm:affiliation>Universidad de La Frontera, Temuco, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Universidad de La Frontera, Temuco</wicri:regionArea></affiliation></author><author><name sortKey="Commerford, Patrick J" sort="Commerford, Patrick J" uniqKey="Commerford P" first="Patrick J" last="Commerford">Patrick J. Commerford</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cardiology, Department of Medicine, University of Cape Town, Temuco, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Division of Cardiology, Department of Medicine, University of Cape Town, Temuco</wicri:regionArea></affiliation></author><author><name sortKey="Torp Pedersen, Christian" sort="Torp Pedersen, Christian" uniqKey="Torp Pedersen C" first="Christian" last="Torp-Pedersen">Christian Torp-Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>University of Aalborg, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>University of Aalborg, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Guzik, Tomasz J" sort="Guzik, Tomasz J" uniqKey="Guzik T" first="Tomasz J" last="Guzik">Tomasz J. Guzik</name><affiliation wicri:level="1"><nlm:affiliation>Collegium Medicum Jagiellonian University, Krakow, Poland; University of Glasgow, Glasgow, Scotland, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Collegium Medicum Jagiellonian University, Krakow, Poland; University of Glasgow, Glasgow, Scotland</wicri:regionArea></affiliation></author><author><name sortKey="Verhamme, Peter B" sort="Verhamme, Peter B" uniqKey="Verhamme P" first="Peter B" last="Verhamme">Peter B. Verhamme</name><affiliation wicri:level="1"><nlm:affiliation>University of Leuven, Flanders, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>University of Leuven, Flanders</wicri:regionArea></affiliation></author><author><name sortKey="Vinereanu, Dragos" sort="Vinereanu, Dragos" uniqKey="Vinereanu D" first="Dragos" last="Vinereanu">Dragos Vinereanu</name><affiliation wicri:level="1"><nlm:affiliation>University of Medicine and Pharmacology Carol Davila University and Emergency Hospital, Bucharest, Romania.</nlm:affiliation><country xml:lang="fr">Roumanie</country><wicri:regionArea>University of Medicine and Pharmacology Carol Davila University and Emergency Hospital, Bucharest</wicri:regionArea></affiliation></author><author><name sortKey="Kim, Jae Hyung" sort="Kim, Jae Hyung" uniqKey="Kim J" first="Jae-Hyung" last="Kim">Jae-Hyung Kim</name><affiliation wicri:level="1"><nlm:affiliation>The Catholic University of Korea, Seoul, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>The Catholic University of Korea, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Ha, Jong Won" sort="Ha, Jong Won" uniqKey="Ha J" first="Jong-Won" last="Ha">Jong-Won Ha</name><affiliation wicri:level="1"><nlm:affiliation>Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Yonsei University College of Medicine, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Tonkin, Andrew M" sort="Tonkin, Andrew M" uniqKey="Tonkin A" first="Andrew M" last="Tonkin">Andrew M. Tonkin</name><affiliation wicri:level="1"><nlm:affiliation>Monash University, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Monash University, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Varigos, John D" sort="Varigos, John D" uniqKey="Varigos J" first="John D" last="Varigos">John D. Varigos</name><affiliation wicri:level="1"><nlm:affiliation>Monash University, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Monash University, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Lewis, Basil S" sort="Lewis, Basil S" uniqKey="Lewis B" first="Basil S" last="Lewis">Basil S. Lewis</name><affiliation wicri:level="1"><nlm:affiliation>Lady Davis Carmel Medical Centre, Haifa, Israel.</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Lady Davis Carmel Medical Centre, Haifa</wicri:regionArea></affiliation></author><author><name sortKey="Felix, Camilo" sort="Felix, Camilo" uniqKey="Felix C" first="Camilo" last="Felix">Camilo Felix</name><affiliation wicri:level="1"><nlm:affiliation>Facultad de Ciencias de la Salud Eugenio Espejo UTE, Quito, Ecuador.</nlm:affiliation><country xml:lang="fr">Équateur</country><wicri:regionArea>Facultad de Ciencias de la Salud Eugenio Espejo UTE, Quito</wicri:regionArea></affiliation></author><author><name sortKey="Yusoff, Khalid" sort="Yusoff, Khalid" uniqKey="Yusoff K" first="Khalid" last="Yusoff">Khalid Yusoff</name><affiliation wicri:level="1"><nlm:affiliation>Universiti Teknologi Mara, Selangor, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Universiti Teknologi Mara, Selangor</wicri:regionArea></affiliation></author><author><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris Diderot, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, FACT, DHU FIRE, INSERM U1148, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris Diderot, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, FACT, DHU FIRE, INSERM U1148, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Aboyans, Victor" sort="Aboyans, Victor" uniqKey="Aboyans V" first="Victor" last="Aboyans">Victor Aboyans</name><affiliation wicri:level="1"><nlm:affiliation>Dupuytren University Hospital, Limoges, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Dupuytren University Hospital, Limoges</wicri:regionArea></affiliation></author><author><name sortKey="Metsarinne, Kaj P" sort="Metsarinne, Kaj P" uniqKey="Metsarinne K" first="Kaj P" last="Metsarinne">Kaj P. Metsarinne</name><affiliation wicri:level="1"><nlm:affiliation>Turku University Central Hospital and Turku University, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Turku University Central Hospital and Turku University, Turku</wicri:regionArea></affiliation></author><author><name sortKey="Anand, Sonia S" sort="Anand, Sonia S" uniqKey="Anand S" first="Sonia S" last="Anand">Sonia S. Anand</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Hart, Robert G" sort="Hart, Robert G" uniqKey="Hart R" first="Robert G" last="Hart">Robert G. Hart</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Lamy, Andre" sort="Lamy, Andre" uniqKey="Lamy A" first="Andre" last="Lamy">Andre Lamy</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Moayyedi, Paul" sort="Moayyedi, Paul" uniqKey="Moayyedi P" first="Paul" last="Moayyedi">Paul Moayyedi</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Leong, Darryl P" sort="Leong, Darryl P" uniqKey="Leong D" first="Darryl P" last="Leong">Darryl P. Leong</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Sharma, Mukul" sort="Sharma, Mukul" uniqKey="Sharma M" first="Mukul" last="Sharma">Mukul Sharma</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Yusuf, Salim" sort="Yusuf, Salim" uniqKey="Yusuf S" first="Salim" last="Yusuf">Salim Yusuf</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28754388</idno><idno type="pmid">28754388</idno><idno type="doi">10.1016/j.cjca.2017.06.001</idno><idno type="wicri:Area/PubMed/Corpus">000809</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000809</idno><idno type="wicri:Area/PubMed/Curation">000806</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000806</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Rationale, Design and Baseline Characteristics of Participants in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) Trial.</title><author><name sortKey="Bosch, Jackie" sort="Bosch, Jackie" uniqKey="Bosch J" first="Jackie" last="Bosch">Jackie Bosch</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada. Electronic address: jackie.bosch@phri.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; School of Rehabilitation Science, McMaster University, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Eikelboom, John W" sort="Eikelboom, John W" uniqKey="Eikelboom J" first="John W" last="Eikelboom">John W. Eikelboom</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Connolly, Stuart J" sort="Connolly, Stuart J" uniqKey="Connolly S" first="Stuart J" last="Connolly">Stuart J. Connolly</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Bruns, Nancy Cook" sort="Bruns, Nancy Cook" uniqKey="Bruns N" first="Nancy Cook" last="Bruns">Nancy Cook Bruns</name><affiliation wicri:level="1"><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Bayer AG, Leverkusen</wicri:regionArea></affiliation></author><author><name sortKey="Lanius, Vivian" sort="Lanius, Vivian" uniqKey="Lanius V" first="Vivian" last="Lanius">Vivian Lanius</name><affiliation wicri:level="1"><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Bayer AG, Leverkusen</wicri:regionArea></affiliation></author><author><name sortKey="Yuan, Fei" sort="Yuan, Fei" uniqKey="Yuan F" first="Fei" last="Yuan">Fei Yuan</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Misselwitz, Frank" sort="Misselwitz, Frank" uniqKey="Misselwitz F" first="Frank" last="Misselwitz">Frank Misselwitz</name><affiliation wicri:level="1"><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Bayer AG, Leverkusen</wicri:regionArea></affiliation></author><author><name sortKey="Chen, Edmond" sort="Chen, Edmond" uniqKey="Chen E" first="Edmond" last="Chen">Edmond Chen</name><affiliation wicri:level="1"><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Bayer AG, Leverkusen</wicri:regionArea></affiliation></author><author><name sortKey="Diaz, Rafael" sort="Diaz, Rafael" uniqKey="Diaz R" first="Rafael" last="Diaz">Rafael Diaz</name><affiliation wicri:level="1"><nlm:affiliation>Estudios Clínicos Latino América and Instituto Cardiovascular de Rosario, Rosario, Argentina.</nlm:affiliation><country xml:lang="fr">Argentine</country><wicri:regionArea>Estudios Clínicos Latino América and Instituto Cardiovascular de Rosario, Rosario</wicri:regionArea></affiliation></author><author><name sortKey="Alings, Marco" sort="Alings, Marco" uniqKey="Alings M" first="Marco" last="Alings">Marco Alings</name><affiliation wicri:level="1"><nlm:affiliation>Amphia Ziekenhuis and WCN, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Amphia Ziekenhuis and WCN, Utrecht</wicri:regionArea></affiliation></author><author><name sortKey="Lonn, Eva M" sort="Lonn, Eva M" uniqKey="Lonn E" first="Eva M" last="Lonn">Eva M. Lonn</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Widimsky, Petr" sort="Widimsky, Petr" uniqKey="Widimsky P" first="Petr" last="Widimsky">Petr Widimsky</name><affiliation wicri:level="1"><nlm:affiliation>Cardiocenter, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University Prague, Prague, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Cardiocenter, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University Prague, Prague</wicri:regionArea></affiliation></author><author><name sortKey="Hori, Masatsugu" sort="Hori, Masatsugu" uniqKey="Hori M" first="Masatsugu" last="Hori">Masatsugu Hori</name><affiliation wicri:level="1"><nlm:affiliation>Osaka International Cancer Institute, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Osaka International Cancer Institute, Osaka</wicri:regionArea></affiliation></author><author><name sortKey="Avezum, Alvaro" sort="Avezum, Alvaro" uniqKey="Avezum A" first="Alvaro" last="Avezum">Alvaro Avezum</name><affiliation wicri:level="1"><nlm:affiliation>Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Instituto Dante Pazzanese de Cardiologia, Sao Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Piegas, Leopoldo S" sort="Piegas, Leopoldo S" uniqKey="Piegas L" first="Leopoldo S" last="Piegas">Leopoldo S. Piegas</name><affiliation wicri:level="1"><nlm:affiliation>University of Sao Paulo, Sao Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>University of Sao Paulo, Sao Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Bhatt, Deepak L" sort="Bhatt, Deepak L" uniqKey="Bhatt D" first="Deepak L" last="Bhatt">Deepak L. Bhatt</name><affiliation wicri:level="1"><nlm:affiliation>Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts</wicri:regionArea></affiliation></author><author><name sortKey="Branch, Kelley R H" sort="Branch, Kelley R H" uniqKey="Branch K" first="Kelley R H" last="Branch">Kelley R H. Branch</name><affiliation wicri:level="1"><nlm:affiliation>University of Washington Medical Centre, Seattle, Washington, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Washington Medical Centre, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Probstfield, Jeffrey L" sort="Probstfield, Jeffrey L" uniqKey="Probstfield J" first="Jeffrey L" last="Probstfield">Jeffrey L. Probstfield</name><affiliation wicri:level="1"><nlm:affiliation>University of Washington, Seattle, Washington, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Washington, Seattle, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Liang, Yan" sort="Liang, Yan" uniqKey="Liang Y" first="Yan" last="Liang">Yan Liang</name><affiliation wicri:level="1"><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>FuWai Hospital, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Lisheng" sort="Liu, Lisheng" uniqKey="Liu L" first="Lisheng" last="Liu">Lisheng Liu</name><affiliation wicri:level="1"><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>FuWai Hospital, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Zhu, Jun" sort="Zhu, Jun" uniqKey="Zhu J" first="Jun" last="Zhu">Jun Zhu</name><affiliation wicri:level="1"><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>FuWai Hospital, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Maggioni, Aldo P" sort="Maggioni, Aldo P" uniqKey="Maggioni A" first="Aldo P" last="Maggioni">Aldo P. Maggioni</name><affiliation wicri:level="1"><nlm:affiliation>ANMCO Research Center, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>ANMCO Research Center, Florence</wicri:regionArea></affiliation></author><author><name sortKey="Lopez Jaramillo, Patricio" sort="Lopez Jaramillo, Patricio" uniqKey="Lopez Jaramillo P" first="Patricio" last="Lopez-Jaramillo">Patricio Lopez-Jaramillo</name><affiliation wicri:level="1"><nlm:affiliation>Research Institute, FOSCAL-Bucaramanga, Bucaramanga, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Research Institute, FOSCAL-Bucaramanga, Bucaramanga</wicri:regionArea></affiliation></author><author><name sortKey="O Donnell, Martin" sort="O Donnell, Martin" uniqKey="O Donnell M" first="Martin" last="O'Donnell">Martin O'Donnell</name><affiliation wicri:level="1"><nlm:affiliation>National University of Ireland, Galway, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>National University of Ireland, Galway</wicri:regionArea></affiliation></author><author><name sortKey="Fox, Keith A A" sort="Fox, Keith A A" uniqKey="Fox K" first="Keith A A" last="Fox">Keith A A. Fox</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Centre for Cardiovascular Science, University of Edinburgh, Edinburgh</wicri:cityArea></affiliation></author><author><name sortKey="Kakkar, Ajay" sort="Kakkar, Ajay" uniqKey="Kakkar A" first="Ajay" last="Kakkar">Ajay Kakkar</name><affiliation wicri:level="1"><nlm:affiliation>University College London Hospitals, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University College London Hospitals, London</wicri:regionArea></affiliation></author><author><name sortKey="Parkhomenko, Alexander N" sort="Parkhomenko, Alexander N" uniqKey="Parkhomenko A" first="Alexander N" last="Parkhomenko">Alexander N. Parkhomenko</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology (Ukraine), Kiev, Ukraine.</nlm:affiliation><country xml:lang="fr">Ukraine</country><wicri:regionArea>Institute of Cardiology (Ukraine), Kiev</wicri:regionArea></affiliation></author><author><name sortKey="Ertl, Georg" sort="Ertl, Georg" uniqKey="Ertl G" first="Georg" last="Ertl">Georg Ertl</name><affiliation wicri:level="1"><nlm:affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg</wicri:regionArea></affiliation></author><author><name sortKey="Stork, Stefan" sort="Stork, Stefan" uniqKey="Stork S" first="Stefan" last="Störk">Stefan Störk</name><affiliation wicri:level="1"><nlm:affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg</wicri:regionArea></affiliation></author><author><name sortKey="Keltai, Katalin" sort="Keltai, Katalin" uniqKey="Keltai K" first="Katalin" last="Keltai">Katalin Keltai</name><affiliation wicri:level="1"><nlm:affiliation>Semmelweis University, Budapest, Hungary.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Semmelweis University, Budapest</wicri:regionArea></affiliation></author><author><name sortKey="Keltai, Matyas" sort="Keltai, Matyas" uniqKey="Keltai M" first="Matyas" last="Keltai">Matyas Keltai</name><affiliation wicri:level="1"><nlm:affiliation>Semmelweis University, Budapest, Hungary.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Semmelweis University, Budapest</wicri:regionArea></affiliation></author><author><name sortKey="Ryden, Lars" sort="Ryden, Lars" uniqKey="Ryden L" first="Lars" last="Ryden">Lars Ryden</name><affiliation wicri:level="1"><nlm:affiliation>Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Karolinska Institutet, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Dagenais, Gilles R" sort="Dagenais, Gilles R" uniqKey="Dagenais G" first="Gilles R" last="Dagenais">Gilles R. Dagenais</name><affiliation wicri:level="1"><nlm:affiliation>Institut Universitaire de Cardiologie et Pneumologie de Quebec, Quebec City, Quebec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Institut Universitaire de Cardiologie et Pneumologie de Quebec, Quebec City, Quebec</wicri:regionArea></affiliation></author><author><name sortKey="Pogosova, Nana" sort="Pogosova, Nana" uniqKey="Pogosova N" first="Nana" last="Pogosova">Nana Pogosova</name><affiliation wicri:level="1"><nlm:affiliation>National Research Centre for Preventative Medicine (Moscow), Moscow, Russia.</nlm:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>National Research Centre for Preventative Medicine (Moscow), Moscow</wicri:regionArea></affiliation></author><author><name sortKey="Dans, Antonio L" sort="Dans, Antonio L" uniqKey="Dans A" first="Antonio L" last="Dans">Antonio L. Dans</name><affiliation><nlm:affiliation>University of Philippines - Manila, Manila, The Philippines.</nlm:affiliation><wicri:noCountry code="subField">The Philippines</wicri:noCountry></affiliation></author><author><name sortKey="Lanas, Fernando" sort="Lanas, Fernando" uniqKey="Lanas F" first="Fernando" last="Lanas">Fernando Lanas</name><affiliation wicri:level="1"><nlm:affiliation>Universidad de La Frontera, Temuco, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Universidad de La Frontera, Temuco</wicri:regionArea></affiliation></author><author><name sortKey="Commerford, Patrick J" sort="Commerford, Patrick J" uniqKey="Commerford P" first="Patrick J" last="Commerford">Patrick J. Commerford</name><affiliation wicri:level="1"><nlm:affiliation>Division of Cardiology, Department of Medicine, University of Cape Town, Temuco, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Division of Cardiology, Department of Medicine, University of Cape Town, Temuco</wicri:regionArea></affiliation></author><author><name sortKey="Torp Pedersen, Christian" sort="Torp Pedersen, Christian" uniqKey="Torp Pedersen C" first="Christian" last="Torp-Pedersen">Christian Torp-Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>University of Aalborg, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>University of Aalborg, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Guzik, Tomasz J" sort="Guzik, Tomasz J" uniqKey="Guzik T" first="Tomasz J" last="Guzik">Tomasz J. Guzik</name><affiliation wicri:level="1"><nlm:affiliation>Collegium Medicum Jagiellonian University, Krakow, Poland; University of Glasgow, Glasgow, Scotland, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Collegium Medicum Jagiellonian University, Krakow, Poland; University of Glasgow, Glasgow, Scotland</wicri:regionArea></affiliation></author><author><name sortKey="Verhamme, Peter B" sort="Verhamme, Peter B" uniqKey="Verhamme P" first="Peter B" last="Verhamme">Peter B. Verhamme</name><affiliation wicri:level="1"><nlm:affiliation>University of Leuven, Flanders, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>University of Leuven, Flanders</wicri:regionArea></affiliation></author><author><name sortKey="Vinereanu, Dragos" sort="Vinereanu, Dragos" uniqKey="Vinereanu D" first="Dragos" last="Vinereanu">Dragos Vinereanu</name><affiliation wicri:level="1"><nlm:affiliation>University of Medicine and Pharmacology Carol Davila University and Emergency Hospital, Bucharest, Romania.</nlm:affiliation><country xml:lang="fr">Roumanie</country><wicri:regionArea>University of Medicine and Pharmacology Carol Davila University and Emergency Hospital, Bucharest</wicri:regionArea></affiliation></author><author><name sortKey="Kim, Jae Hyung" sort="Kim, Jae Hyung" uniqKey="Kim J" first="Jae-Hyung" last="Kim">Jae-Hyung Kim</name><affiliation wicri:level="1"><nlm:affiliation>The Catholic University of Korea, Seoul, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>The Catholic University of Korea, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Ha, Jong Won" sort="Ha, Jong Won" uniqKey="Ha J" first="Jong-Won" last="Ha">Jong-Won Ha</name><affiliation wicri:level="1"><nlm:affiliation>Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Yonsei University College of Medicine, Seoul</wicri:regionArea></affiliation></author><author><name sortKey="Tonkin, Andrew M" sort="Tonkin, Andrew M" uniqKey="Tonkin A" first="Andrew M" last="Tonkin">Andrew M. Tonkin</name><affiliation wicri:level="1"><nlm:affiliation>Monash University, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Monash University, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Varigos, John D" sort="Varigos, John D" uniqKey="Varigos J" first="John D" last="Varigos">John D. Varigos</name><affiliation wicri:level="1"><nlm:affiliation>Monash University, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Monash University, Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Lewis, Basil S" sort="Lewis, Basil S" uniqKey="Lewis B" first="Basil S" last="Lewis">Basil S. Lewis</name><affiliation wicri:level="1"><nlm:affiliation>Lady Davis Carmel Medical Centre, Haifa, Israel.</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Lady Davis Carmel Medical Centre, Haifa</wicri:regionArea></affiliation></author><author><name sortKey="Felix, Camilo" sort="Felix, Camilo" uniqKey="Felix C" first="Camilo" last="Felix">Camilo Felix</name><affiliation wicri:level="1"><nlm:affiliation>Facultad de Ciencias de la Salud Eugenio Espejo UTE, Quito, Ecuador.</nlm:affiliation><country xml:lang="fr">Équateur</country><wicri:regionArea>Facultad de Ciencias de la Salud Eugenio Espejo UTE, Quito</wicri:regionArea></affiliation></author><author><name sortKey="Yusoff, Khalid" sort="Yusoff, Khalid" uniqKey="Yusoff K" first="Khalid" last="Yusoff">Khalid Yusoff</name><affiliation wicri:level="1"><nlm:affiliation>Universiti Teknologi Mara, Selangor, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Universiti Teknologi Mara, Selangor</wicri:regionArea></affiliation></author><author><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris Diderot, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, FACT, DHU FIRE, INSERM U1148, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris Diderot, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, FACT, DHU FIRE, INSERM U1148, Paris</wicri:regionArea></affiliation></author><author><name sortKey="Aboyans, Victor" sort="Aboyans, Victor" uniqKey="Aboyans V" first="Victor" last="Aboyans">Victor Aboyans</name><affiliation wicri:level="1"><nlm:affiliation>Dupuytren University Hospital, Limoges, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Dupuytren University Hospital, Limoges</wicri:regionArea></affiliation></author><author><name sortKey="Metsarinne, Kaj P" sort="Metsarinne, Kaj P" uniqKey="Metsarinne K" first="Kaj P" last="Metsarinne">Kaj P. Metsarinne</name><affiliation wicri:level="1"><nlm:affiliation>Turku University Central Hospital and Turku University, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Turku University Central Hospital and Turku University, Turku</wicri:regionArea></affiliation></author><author><name sortKey="Anand, Sonia S" sort="Anand, Sonia S" uniqKey="Anand S" first="Sonia S" last="Anand">Sonia S. Anand</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Hart, Robert G" sort="Hart, Robert G" uniqKey="Hart R" first="Robert G" last="Hart">Robert G. Hart</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Lamy, Andre" sort="Lamy, Andre" uniqKey="Lamy A" first="Andre" last="Lamy">Andre Lamy</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Moayyedi, Paul" sort="Moayyedi, Paul" uniqKey="Moayyedi P" first="Paul" last="Moayyedi">Paul Moayyedi</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Leong, Darryl P" sort="Leong, Darryl P" uniqKey="Leong D" first="Darryl P" last="Leong">Darryl P. Leong</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Sharma, Mukul" sort="Sharma, Mukul" uniqKey="Sharma M" first="Mukul" last="Sharma">Mukul Sharma</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Yusuf, Salim" sort="Yusuf, Salim" uniqKey="Yusuf S" first="Salim" last="Yusuf">Salim Yusuf</name><affiliation wicri:level="1"><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario</wicri:regionArea></affiliation></author></analytic><series><title level="j">The Canadian journal of cardiology</title><idno type="eISSN">1916-7075</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anticoagulants (therapeutic use)</term><term>Cardiovascular Diseases (prevention & control)</term><term>Humans</term><term>Practice Guidelines as Topic</term><term>Randomized Controlled Trials as Topic (methods)</term><term>Thrombolytic Therapy (standards)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Anticoagulants (usage thérapeutique)</term><term>Essais contrôlés randomisés comme sujet ()</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Maladies cardiovasculaires ()</term><term>Traitement thrombolytique (normes)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anticoagulants</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Randomized Controlled Trials as Topic</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Traitement thrombolytique</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Cardiovascular Diseases</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Thrombolytic Therapy</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Anticoagulants</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Practice Guidelines as Topic</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Essais contrôlés randomisés comme sujet</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Maladies cardiovasculaires</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Long-term aspirin prevents vascular events but is only modestly effective. Rivaroxaban alone or in combination with aspirin might be more effective than aspirin alone for vascular prevention in patients with stable coronary artery disease (CAD) or peripheral artery disease (PAD). Rivaroxaban as well as aspirin increase upper gastrointestinal (GI) bleeding and this might be prevented by proton pump inhibitor therapy.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28754388</PMID><DateCreated><Year>2017</Year><Month>07</Month><Day>29</Day></DateCreated><DateCompleted><Year>2017</Year><Month>09</Month><Day>01</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>01</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1916-7075</ISSN><JournalIssue CitedMedium="Internet"><Volume>33</Volume><Issue>8</Issue><PubDate><Year>2017</Year><Month>Aug</Month></PubDate></JournalIssue><Title>The Canadian journal of cardiology</Title><ISOAbbreviation>Can J Cardiol</ISOAbbreviation></Journal><ArticleTitle>Rationale, Design and Baseline Characteristics of Participants in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) Trial.</ArticleTitle><Pagination><MedlinePgn>1027-1035</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0828-282X(17)30306-9</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.cjca.2017.06.001</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Long-term aspirin prevents vascular events but is only modestly effective. Rivaroxaban alone or in combination with aspirin might be more effective than aspirin alone for vascular prevention in patients with stable coronary artery disease (CAD) or peripheral artery disease (PAD). Rivaroxaban as well as aspirin increase upper gastrointestinal (GI) bleeding and this might be prevented by proton pump inhibitor therapy.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) is a double-blind superiority trial comparing rivaroxaban 2.5 mg twice daily combined with aspirin 100 mg once daily or rivaroxaban 5 mg twice daily vs aspirin 100 mg once daily for prevention of myocardial infarction, stroke, or cardiovascular death in patients with stable CAD or PAD. Patients not taking a proton pump inhibitor were also randomized, using a partial factorial design, to pantoprazole 40 mg once daily or placebo. The trial was designed to have at least 90% power to detect a 20% reduction in each of the rivaroxaban treatment arms compared with aspirin and to detect a 50% reduction in upper GI complications with pantoprazole compared with placebo.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Between February 2013 and May 2016, we recruited 27,395 participants from 602 centres in 33 countries; 17,598 participants were included in the pantoprazole vs placebo comparison. At baseline, the mean age was 68.2 years, 22.0% were female, 90.6% had CAD, and 27.3% had PAD.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">COMPASS will provide information on the efficacy and safety of rivaroxaban, alone or in combination with aspirin, in the long-term management of patients with stable CAD or PAD, and on the efficacy and safety of pantoprazole in preventing upper GI complications in patients receiving antithrombotic therapy.</AbstractText><CopyrightInformation>Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bosch</LastName><ForeName>Jackie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada. Electronic address: jackie.bosch@phri.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eikelboom</LastName><ForeName>John W</ForeName><Initials>JW</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Connolly</LastName><ForeName>Stuart J</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bruns</LastName><ForeName>Nancy Cook</ForeName><Initials>NC</Initials><AffiliationInfo><Affiliation>Bayer AG, Leverkusen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lanius</LastName><ForeName>Vivian</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Bayer AG, Leverkusen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yuan</LastName><ForeName>Fei</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Misselwitz</LastName><ForeName>Frank</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Bayer AG, Leverkusen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Edmond</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Bayer AG, Leverkusen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Diaz</LastName><ForeName>Rafael</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Estudios Clínicos Latino América and Instituto Cardiovascular de Rosario, Rosario, Argentina.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alings</LastName><ForeName>Marco</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Amphia Ziekenhuis and WCN, Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lonn</LastName><ForeName>Eva M</ForeName><Initials>EM</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Widimsky</LastName><ForeName>Petr</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Cardiocenter, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University Prague, Prague, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hori</LastName><ForeName>Masatsugu</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Osaka International Cancer Institute, Osaka, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Avezum</LastName><ForeName>Alvaro</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Piegas</LastName><ForeName>Leopoldo S</ForeName><Initials>LS</Initials><AffiliationInfo><Affiliation>University of Sao Paulo, Sao Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bhatt</LastName><ForeName>Deepak L</ForeName><Initials>DL</Initials><AffiliationInfo><Affiliation>Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Branch</LastName><ForeName>Kelley R H</ForeName><Initials>KRH</Initials><AffiliationInfo><Affiliation>University of Washington Medical Centre, Seattle, Washington, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Probstfield</LastName><ForeName>Jeffrey L</ForeName><Initials>JL</Initials><AffiliationInfo><Affiliation>University of Washington, Seattle, Washington, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liang</LastName><ForeName>Yan</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>FuWai Hospital, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Lisheng</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>FuWai Hospital, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhu</LastName><ForeName>Jun</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>FuWai Hospital, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maggioni</LastName><ForeName>Aldo P</ForeName><Initials>AP</Initials><AffiliationInfo><Affiliation>ANMCO Research Center, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lopez-Jaramillo</LastName><ForeName>Patricio</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Research Institute, FOSCAL-Bucaramanga, Bucaramanga, Colombia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Donnell</LastName><ForeName>Martin</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>National University of Ireland, Galway, Ireland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fox</LastName><ForeName>Keith A A</ForeName><Initials>KAA</Initials><AffiliationInfo><Affiliation>Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kakkar</LastName><ForeName>Ajay</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>University College London Hospitals, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Parkhomenko</LastName><ForeName>Alexander N</ForeName><Initials>AN</Initials><AffiliationInfo><Affiliation>Institute of Cardiology (Ukraine), Kiev, Ukraine.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ertl</LastName><ForeName>Georg</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Störk</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keltai</LastName><ForeName>Katalin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Semmelweis University, Budapest, Hungary.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keltai</LastName><ForeName>Matyas</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Semmelweis University, Budapest, Hungary.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ryden</LastName><ForeName>Lars</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dagenais</LastName><ForeName>Gilles R</ForeName><Initials>GR</Initials><AffiliationInfo><Affiliation>Institut Universitaire de Cardiologie et Pneumologie de Quebec, Quebec City, Quebec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pogosova</LastName><ForeName>Nana</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>National Research Centre for Preventative Medicine (Moscow), Moscow, Russia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dans</LastName><ForeName>Antonio L</ForeName><Initials>AL</Initials><AffiliationInfo><Affiliation>University of Philippines - Manila, Manila, The Philippines.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lanas</LastName><ForeName>Fernando</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Universidad de La Frontera, Temuco, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Commerford</LastName><ForeName>Patrick J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Division of Cardiology, Department of Medicine, University of Cape Town, Temuco, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Torp-Pedersen</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>University of Aalborg, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guzik</LastName><ForeName>Tomasz J</ForeName><Initials>TJ</Initials><AffiliationInfo><Affiliation>Collegium Medicum Jagiellonian University, Krakow, Poland; University of Glasgow, Glasgow, Scotland, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Verhamme</LastName><ForeName>Peter B</ForeName><Initials>PB</Initials><AffiliationInfo><Affiliation>University of Leuven, Flanders, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vinereanu</LastName><ForeName>Dragos</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>University of Medicine and Pharmacology Carol Davila University and Emergency Hospital, Bucharest, Romania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Jae-Hyung</ForeName><Initials>JH</Initials><AffiliationInfo><Affiliation>The Catholic University of Korea, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ha</LastName><ForeName>Jong-Won</ForeName><Initials>JW</Initials><AffiliationInfo><Affiliation>Yonsei University College of Medicine, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tonkin</LastName><ForeName>Andrew M</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Monash University, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Varigos</LastName><ForeName>John D</ForeName><Initials>JD</Initials><AffiliationInfo><Affiliation>Monash University, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lewis</LastName><ForeName>Basil S</ForeName><Initials>BS</Initials><AffiliationInfo><Affiliation>Lady Davis Carmel Medical Centre, Haifa, Israel.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Felix</LastName><ForeName>Camilo</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Facultad de Ciencias de la Salud Eugenio Espejo UTE, Quito, Ecuador.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yusoff</LastName><ForeName>Khalid</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Universiti Teknologi Mara, Selangor, Malaysia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Steg</LastName><ForeName>Philippe Gabriel</ForeName><Initials>PG</Initials><AffiliationInfo><Affiliation>Université Paris Diderot, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, FACT, DHU FIRE, INSERM U1148, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aboyans</LastName><ForeName>Victor</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Dupuytren University Hospital, Limoges, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Metsarinne</LastName><ForeName>Kaj P</ForeName><Initials>KP</Initials><AffiliationInfo><Affiliation>Turku University Central Hospital and Turku University, Turku, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Anand</LastName><ForeName>Sonia S</ForeName><Initials>SS</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hart</LastName><ForeName>Robert G</ForeName><Initials>RG</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lamy</LastName><ForeName>Andre</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moayyedi</LastName><ForeName>Paul</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Leong</LastName><ForeName>Darryl P</ForeName><Initials>DP</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sharma</LastName><ForeName>Mukul</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yusuf</LastName><ForeName>Salim</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>06</Month><Day>08</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Can J Cardiol</MedlineTA><NlmUniqueID>8510280</NlmUniqueID><ISSNLinking>0828-282X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000925">Anticoagulants</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000925" MajorTopicYN="N">Anticoagulants</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002318" MajorTopicYN="N">Cardiovascular Diseases</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017410" MajorTopicYN="Y">Practice Guidelines as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016032" MajorTopicYN="N">Randomized Controlled Trials as Topic</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015912" MajorTopicYN="N">Thrombolytic Therapy</DescriptorName><QualifierName UI="Q000592" MajorTopicYN="Y">standards</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>05</Month><Day>25</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>06</Month><Day>04</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>06</Month><Day>04</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>7</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>7</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>9</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28754388</ArticleId><ArticleId IdType="pii">S0828-282X(17)30306-9</ArticleId><ArticleId IdType="doi">10.1016/j.cjca.2017.06.001</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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