Rationale, Design and Baseline Characteristics of Participants in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) Trial.
Identifieur interne : 000809 ( PubMed/Corpus ); précédent : 000808; suivant : 000810Rationale, Design and Baseline Characteristics of Participants in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) Trial.
Auteurs : Jackie Bosch ; John W. Eikelboom ; Stuart J. Connolly ; Nancy Cook Bruns ; Vivian Lanius ; Fei Yuan ; Frank Misselwitz ; Edmond Chen ; Rafael Diaz ; Marco Alings ; Eva M. Lonn ; Petr Widimsky ; Masatsugu Hori ; Alvaro Avezum ; Leopoldo S. Piegas ; Deepak L. Bhatt ; Kelley R H. Branch ; Jeffrey L. Probstfield ; Yan Liang ; Lisheng Liu ; Jun Zhu ; Aldo P. Maggioni ; Patricio Lopez-Jaramillo ; Martin O'Donnell ; Keith A A. Fox ; Ajay Kakkar ; Alexander N. Parkhomenko ; Georg Ertl ; Stefan Störk ; Katalin Keltai ; Matyas Keltai ; Lars Ryden ; Gilles R. Dagenais ; Nana Pogosova ; Antonio L. Dans ; Fernando Lanas ; Patrick J. Commerford ; Christian Torp-Pedersen ; Tomasz J. Guzik ; Peter B. Verhamme ; Dragos Vinereanu ; Jae-Hyung Kim ; Jong-Won Ha ; Andrew M. Tonkin ; John D. Varigos ; Basil S. Lewis ; Camilo Felix ; Khalid Yusoff ; Philippe Gabriel Steg ; Victor Aboyans ; Kaj P. Metsarinne ; Sonia S. Anand ; Robert G. Hart ; Andre Lamy ; Paul Moayyedi ; Darryl P. Leong ; Mukul Sharma ; Salim YusufSource :
- The Canadian journal of cardiology [ 1916-7075 ] ; 2017.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Anticoagulants.
- methods : Randomized Controlled Trials as Topic.
- prevention & control : Cardiovascular Diseases.
- standards : Thrombolytic Therapy.
- Humans, Practice Guidelines as Topic.
Abstract
Long-term aspirin prevents vascular events but is only modestly effective. Rivaroxaban alone or in combination with aspirin might be more effective than aspirin alone for vascular prevention in patients with stable coronary artery disease (CAD) or peripheral artery disease (PAD). Rivaroxaban as well as aspirin increase upper gastrointestinal (GI) bleeding and this might be prevented by proton pump inhibitor therapy.
DOI: 10.1016/j.cjca.2017.06.001
PubMed: 28754388
Links to Exploration step
pubmed:28754388Le document en format XML
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Eikelboom</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Connolly, Stuart J" sort="Connolly, Stuart J" uniqKey="Connolly S" first="Stuart J" last="Connolly">Stuart J. Connolly</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Bruns, Nancy Cook" sort="Bruns, Nancy Cook" uniqKey="Bruns N" first="Nancy Cook" last="Bruns">Nancy Cook Bruns</name><affiliation><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Lanius, Vivian" sort="Lanius, Vivian" uniqKey="Lanius V" first="Vivian" last="Lanius">Vivian Lanius</name><affiliation><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Yuan, Fei" sort="Yuan, Fei" uniqKey="Yuan F" first="Fei" last="Yuan">Fei Yuan</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Misselwitz, Frank" sort="Misselwitz, Frank" uniqKey="Misselwitz F" first="Frank" last="Misselwitz">Frank Misselwitz</name><affiliation><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, Edmond" sort="Chen, Edmond" uniqKey="Chen E" first="Edmond" last="Chen">Edmond Chen</name><affiliation><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Diaz, Rafael" sort="Diaz, Rafael" uniqKey="Diaz R" first="Rafael" last="Diaz">Rafael Diaz</name><affiliation><nlm:affiliation>Estudios Clínicos Latino América and Instituto Cardiovascular de Rosario, Rosario, Argentina.</nlm:affiliation></affiliation></author><author><name sortKey="Alings, Marco" sort="Alings, Marco" uniqKey="Alings M" first="Marco" last="Alings">Marco Alings</name><affiliation><nlm:affiliation>Amphia Ziekenhuis and WCN, Utrecht, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Lonn, Eva M" sort="Lonn, Eva M" uniqKey="Lonn E" first="Eva M" last="Lonn">Eva M. Lonn</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Widimsky, Petr" sort="Widimsky, Petr" uniqKey="Widimsky P" first="Petr" last="Widimsky">Petr Widimsky</name><affiliation><nlm:affiliation>Cardiocenter, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University Prague, Prague, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Hori, Masatsugu" sort="Hori, Masatsugu" uniqKey="Hori M" first="Masatsugu" last="Hori">Masatsugu Hori</name><affiliation><nlm:affiliation>Osaka International Cancer Institute, Osaka, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Avezum, Alvaro" sort="Avezum, Alvaro" uniqKey="Avezum A" first="Alvaro" last="Avezum">Alvaro Avezum</name><affiliation><nlm:affiliation>Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil.</nlm:affiliation></affiliation></author><author><name sortKey="Piegas, Leopoldo S" sort="Piegas, Leopoldo S" uniqKey="Piegas L" first="Leopoldo S" last="Piegas">Leopoldo S. Piegas</name><affiliation><nlm:affiliation>University of Sao Paulo, Sao Paulo, Brazil.</nlm:affiliation></affiliation></author><author><name sortKey="Bhatt, Deepak L" sort="Bhatt, Deepak L" uniqKey="Bhatt D" first="Deepak L" last="Bhatt">Deepak L. Bhatt</name><affiliation><nlm:affiliation>Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Branch, Kelley R H" sort="Branch, Kelley R H" uniqKey="Branch K" first="Kelley R H" last="Branch">Kelley R H. Branch</name><affiliation><nlm:affiliation>University of Washington Medical Centre, Seattle, Washington, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Probstfield, Jeffrey L" sort="Probstfield, Jeffrey L" uniqKey="Probstfield J" first="Jeffrey L" last="Probstfield">Jeffrey L. Probstfield</name><affiliation><nlm:affiliation>University of Washington, Seattle, Washington, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Liang, Yan" sort="Liang, Yan" uniqKey="Liang Y" first="Yan" last="Liang">Yan Liang</name><affiliation><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation></affiliation></author><author><name sortKey="Liu, Lisheng" sort="Liu, Lisheng" uniqKey="Liu L" first="Lisheng" last="Liu">Lisheng Liu</name><affiliation><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhu, Jun" sort="Zhu, Jun" uniqKey="Zhu J" first="Jun" last="Zhu">Jun Zhu</name><affiliation><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation></affiliation></author><author><name sortKey="Maggioni, Aldo P" sort="Maggioni, Aldo P" uniqKey="Maggioni A" first="Aldo P" last="Maggioni">Aldo P. Maggioni</name><affiliation><nlm:affiliation>ANMCO Research Center, Florence, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Lopez Jaramillo, Patricio" sort="Lopez Jaramillo, Patricio" uniqKey="Lopez Jaramillo P" first="Patricio" last="Lopez-Jaramillo">Patricio Lopez-Jaramillo</name><affiliation><nlm:affiliation>Research Institute, FOSCAL-Bucaramanga, Bucaramanga, Colombia.</nlm:affiliation></affiliation></author><author><name sortKey="O Donnell, Martin" sort="O Donnell, Martin" uniqKey="O Donnell M" first="Martin" last="O'Donnell">Martin O'Donnell</name><affiliation><nlm:affiliation>National University of Ireland, Galway, Ireland.</nlm:affiliation></affiliation></author><author><name sortKey="Fox, Keith A A" sort="Fox, Keith A A" uniqKey="Fox K" first="Keith A A" last="Fox">Keith A A. Fox</name><affiliation><nlm:affiliation>Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation></affiliation></author><author><name sortKey="Kakkar, Ajay" sort="Kakkar, Ajay" uniqKey="Kakkar A" first="Ajay" last="Kakkar">Ajay Kakkar</name><affiliation><nlm:affiliation>University College London Hospitals, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Parkhomenko, Alexander N" sort="Parkhomenko, Alexander N" uniqKey="Parkhomenko A" first="Alexander N" last="Parkhomenko">Alexander N. Parkhomenko</name><affiliation><nlm:affiliation>Institute of Cardiology (Ukraine), Kiev, Ukraine.</nlm:affiliation></affiliation></author><author><name sortKey="Ertl, Georg" sort="Ertl, Georg" uniqKey="Ertl G" first="Georg" last="Ertl">Georg Ertl</name><affiliation><nlm:affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Stork, Stefan" sort="Stork, Stefan" uniqKey="Stork S" first="Stefan" last="Störk">Stefan Störk</name><affiliation><nlm:affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Keltai, Katalin" sort="Keltai, Katalin" uniqKey="Keltai K" first="Katalin" last="Keltai">Katalin Keltai</name><affiliation><nlm:affiliation>Semmelweis University, Budapest, Hungary.</nlm:affiliation></affiliation></author><author><name sortKey="Keltai, Matyas" sort="Keltai, Matyas" uniqKey="Keltai M" first="Matyas" last="Keltai">Matyas Keltai</name><affiliation><nlm:affiliation>Semmelweis University, Budapest, Hungary.</nlm:affiliation></affiliation></author><author><name sortKey="Ryden, Lars" sort="Ryden, Lars" uniqKey="Ryden L" first="Lars" last="Ryden">Lars Ryden</name><affiliation><nlm:affiliation>Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Dagenais, Gilles R" sort="Dagenais, Gilles R" uniqKey="Dagenais G" first="Gilles R" last="Dagenais">Gilles R. Dagenais</name><affiliation><nlm:affiliation>Institut Universitaire de Cardiologie et Pneumologie de Quebec, Quebec City, Quebec, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Pogosova, Nana" sort="Pogosova, Nana" uniqKey="Pogosova N" first="Nana" last="Pogosova">Nana Pogosova</name><affiliation><nlm:affiliation>National Research Centre for Preventative Medicine (Moscow), Moscow, Russia.</nlm:affiliation></affiliation></author><author><name sortKey="Dans, Antonio L" sort="Dans, Antonio L" uniqKey="Dans A" first="Antonio L" last="Dans">Antonio L. Dans</name><affiliation><nlm:affiliation>University of Philippines - Manila, Manila, The Philippines.</nlm:affiliation></affiliation></author><author><name sortKey="Lanas, Fernando" sort="Lanas, Fernando" uniqKey="Lanas F" first="Fernando" last="Lanas">Fernando Lanas</name><affiliation><nlm:affiliation>Universidad de La Frontera, Temuco, Chile.</nlm:affiliation></affiliation></author><author><name sortKey="Commerford, Patrick J" sort="Commerford, Patrick J" uniqKey="Commerford P" first="Patrick J" last="Commerford">Patrick J. Commerford</name><affiliation><nlm:affiliation>Division of Cardiology, Department of Medicine, University of Cape Town, Temuco, Chile.</nlm:affiliation></affiliation></author><author><name sortKey="Torp Pedersen, Christian" sort="Torp Pedersen, Christian" uniqKey="Torp Pedersen C" first="Christian" last="Torp-Pedersen">Christian Torp-Pedersen</name><affiliation><nlm:affiliation>University of Aalborg, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Guzik, Tomasz J" sort="Guzik, Tomasz J" uniqKey="Guzik T" first="Tomasz J" last="Guzik">Tomasz J. Guzik</name><affiliation><nlm:affiliation>Collegium Medicum Jagiellonian University, Krakow, Poland; University of Glasgow, Glasgow, Scotland, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Verhamme, Peter B" sort="Verhamme, Peter B" uniqKey="Verhamme P" first="Peter B" last="Verhamme">Peter B. Verhamme</name><affiliation><nlm:affiliation>University of Leuven, Flanders, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Vinereanu, Dragos" sort="Vinereanu, Dragos" uniqKey="Vinereanu D" first="Dragos" last="Vinereanu">Dragos Vinereanu</name><affiliation><nlm:affiliation>University of Medicine and Pharmacology Carol Davila University and Emergency Hospital, Bucharest, Romania.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Jae Hyung" sort="Kim, Jae Hyung" uniqKey="Kim J" first="Jae-Hyung" last="Kim">Jae-Hyung Kim</name><affiliation><nlm:affiliation>The Catholic University of Korea, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Ha, Jong Won" sort="Ha, Jong Won" uniqKey="Ha J" first="Jong-Won" last="Ha">Jong-Won Ha</name><affiliation><nlm:affiliation>Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Tonkin, Andrew M" sort="Tonkin, Andrew M" uniqKey="Tonkin A" first="Andrew M" last="Tonkin">Andrew M. Tonkin</name><affiliation><nlm:affiliation>Monash University, Melbourne, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Varigos, John D" sort="Varigos, John D" uniqKey="Varigos J" first="John D" last="Varigos">John D. Varigos</name><affiliation><nlm:affiliation>Monash University, Melbourne, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Lewis, Basil S" sort="Lewis, Basil S" uniqKey="Lewis B" first="Basil S" last="Lewis">Basil S. Lewis</name><affiliation><nlm:affiliation>Lady Davis Carmel Medical Centre, Haifa, Israel.</nlm:affiliation></affiliation></author><author><name sortKey="Felix, Camilo" sort="Felix, Camilo" uniqKey="Felix C" first="Camilo" last="Felix">Camilo Felix</name><affiliation><nlm:affiliation>Facultad de Ciencias de la Salud Eugenio Espejo UTE, Quito, Ecuador.</nlm:affiliation></affiliation></author><author><name sortKey="Yusoff, Khalid" sort="Yusoff, Khalid" uniqKey="Yusoff K" first="Khalid" last="Yusoff">Khalid Yusoff</name><affiliation><nlm:affiliation>Universiti Teknologi Mara, Selangor, Malaysia.</nlm:affiliation></affiliation></author><author><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name><affiliation><nlm:affiliation>Université Paris Diderot, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, FACT, DHU FIRE, INSERM U1148, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Aboyans, Victor" sort="Aboyans, Victor" uniqKey="Aboyans V" first="Victor" last="Aboyans">Victor Aboyans</name><affiliation><nlm:affiliation>Dupuytren University Hospital, Limoges, France.</nlm:affiliation></affiliation></author><author><name sortKey="Metsarinne, Kaj P" sort="Metsarinne, Kaj P" uniqKey="Metsarinne K" first="Kaj P" last="Metsarinne">Kaj P. Metsarinne</name><affiliation><nlm:affiliation>Turku University Central Hospital and Turku University, Turku, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Anand, Sonia S" sort="Anand, Sonia S" uniqKey="Anand S" first="Sonia S" last="Anand">Sonia S. Anand</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Hart, Robert G" sort="Hart, Robert G" uniqKey="Hart R" first="Robert G" last="Hart">Robert G. Hart</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Lamy, Andre" sort="Lamy, Andre" uniqKey="Lamy A" first="Andre" last="Lamy">Andre Lamy</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Moayyedi, Paul" sort="Moayyedi, Paul" uniqKey="Moayyedi P" first="Paul" last="Moayyedi">Paul Moayyedi</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Leong, Darryl P" sort="Leong, Darryl P" uniqKey="Leong D" first="Darryl P" last="Leong">Darryl P. Leong</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Sharma, Mukul" sort="Sharma, Mukul" uniqKey="Sharma M" first="Mukul" last="Sharma">Mukul Sharma</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Yusuf, Salim" sort="Yusuf, Salim" uniqKey="Yusuf S" first="Salim" last="Yusuf">Salim Yusuf</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28754388</idno><idno type="pmid">28754388</idno><idno type="doi">10.1016/j.cjca.2017.06.001</idno><idno type="wicri:Area/PubMed/Corpus">000809</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000809</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Rationale, Design and Baseline Characteristics of Participants in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) Trial.</title><author><name sortKey="Bosch, Jackie" sort="Bosch, Jackie" uniqKey="Bosch J" first="Jackie" last="Bosch">Jackie Bosch</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada. Electronic address: jackie.bosch@phri.ca.</nlm:affiliation></affiliation></author><author><name sortKey="Eikelboom, John W" sort="Eikelboom, John W" uniqKey="Eikelboom J" first="John W" last="Eikelboom">John W. Eikelboom</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Connolly, Stuart J" sort="Connolly, Stuart J" uniqKey="Connolly S" first="Stuart J" last="Connolly">Stuart J. Connolly</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Bruns, Nancy Cook" sort="Bruns, Nancy Cook" uniqKey="Bruns N" first="Nancy Cook" last="Bruns">Nancy Cook Bruns</name><affiliation><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Lanius, Vivian" sort="Lanius, Vivian" uniqKey="Lanius V" first="Vivian" last="Lanius">Vivian Lanius</name><affiliation><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Yuan, Fei" sort="Yuan, Fei" uniqKey="Yuan F" first="Fei" last="Yuan">Fei Yuan</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Misselwitz, Frank" sort="Misselwitz, Frank" uniqKey="Misselwitz F" first="Frank" last="Misselwitz">Frank Misselwitz</name><affiliation><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, Edmond" sort="Chen, Edmond" uniqKey="Chen E" first="Edmond" last="Chen">Edmond Chen</name><affiliation><nlm:affiliation>Bayer AG, Leverkusen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Diaz, Rafael" sort="Diaz, Rafael" uniqKey="Diaz R" first="Rafael" last="Diaz">Rafael Diaz</name><affiliation><nlm:affiliation>Estudios Clínicos Latino América and Instituto Cardiovascular de Rosario, Rosario, Argentina.</nlm:affiliation></affiliation></author><author><name sortKey="Alings, Marco" sort="Alings, Marco" uniqKey="Alings M" first="Marco" last="Alings">Marco Alings</name><affiliation><nlm:affiliation>Amphia Ziekenhuis and WCN, Utrecht, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Lonn, Eva M" sort="Lonn, Eva M" uniqKey="Lonn E" first="Eva M" last="Lonn">Eva M. Lonn</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Widimsky, Petr" sort="Widimsky, Petr" uniqKey="Widimsky P" first="Petr" last="Widimsky">Petr Widimsky</name><affiliation><nlm:affiliation>Cardiocenter, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University Prague, Prague, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Hori, Masatsugu" sort="Hori, Masatsugu" uniqKey="Hori M" first="Masatsugu" last="Hori">Masatsugu Hori</name><affiliation><nlm:affiliation>Osaka International Cancer Institute, Osaka, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Avezum, Alvaro" sort="Avezum, Alvaro" uniqKey="Avezum A" first="Alvaro" last="Avezum">Alvaro Avezum</name><affiliation><nlm:affiliation>Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil.</nlm:affiliation></affiliation></author><author><name sortKey="Piegas, Leopoldo S" sort="Piegas, Leopoldo S" uniqKey="Piegas L" first="Leopoldo S" last="Piegas">Leopoldo S. Piegas</name><affiliation><nlm:affiliation>University of Sao Paulo, Sao Paulo, Brazil.</nlm:affiliation></affiliation></author><author><name sortKey="Bhatt, Deepak L" sort="Bhatt, Deepak L" uniqKey="Bhatt D" first="Deepak L" last="Bhatt">Deepak L. Bhatt</name><affiliation><nlm:affiliation>Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Branch, Kelley R H" sort="Branch, Kelley R H" uniqKey="Branch K" first="Kelley R H" last="Branch">Kelley R H. Branch</name><affiliation><nlm:affiliation>University of Washington Medical Centre, Seattle, Washington, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Probstfield, Jeffrey L" sort="Probstfield, Jeffrey L" uniqKey="Probstfield J" first="Jeffrey L" last="Probstfield">Jeffrey L. Probstfield</name><affiliation><nlm:affiliation>University of Washington, Seattle, Washington, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Liang, Yan" sort="Liang, Yan" uniqKey="Liang Y" first="Yan" last="Liang">Yan Liang</name><affiliation><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation></affiliation></author><author><name sortKey="Liu, Lisheng" sort="Liu, Lisheng" uniqKey="Liu L" first="Lisheng" last="Liu">Lisheng Liu</name><affiliation><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhu, Jun" sort="Zhu, Jun" uniqKey="Zhu J" first="Jun" last="Zhu">Jun Zhu</name><affiliation><nlm:affiliation>FuWai Hospital, Beijing, China.</nlm:affiliation></affiliation></author><author><name sortKey="Maggioni, Aldo P" sort="Maggioni, Aldo P" uniqKey="Maggioni A" first="Aldo P" last="Maggioni">Aldo P. Maggioni</name><affiliation><nlm:affiliation>ANMCO Research Center, Florence, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Lopez Jaramillo, Patricio" sort="Lopez Jaramillo, Patricio" uniqKey="Lopez Jaramillo P" first="Patricio" last="Lopez-Jaramillo">Patricio Lopez-Jaramillo</name><affiliation><nlm:affiliation>Research Institute, FOSCAL-Bucaramanga, Bucaramanga, Colombia.</nlm:affiliation></affiliation></author><author><name sortKey="O Donnell, Martin" sort="O Donnell, Martin" uniqKey="O Donnell M" first="Martin" last="O'Donnell">Martin O'Donnell</name><affiliation><nlm:affiliation>National University of Ireland, Galway, Ireland.</nlm:affiliation></affiliation></author><author><name sortKey="Fox, Keith A A" sort="Fox, Keith A A" uniqKey="Fox K" first="Keith A A" last="Fox">Keith A A. Fox</name><affiliation><nlm:affiliation>Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation></affiliation></author><author><name sortKey="Kakkar, Ajay" sort="Kakkar, Ajay" uniqKey="Kakkar A" first="Ajay" last="Kakkar">Ajay Kakkar</name><affiliation><nlm:affiliation>University College London Hospitals, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Parkhomenko, Alexander N" sort="Parkhomenko, Alexander N" uniqKey="Parkhomenko A" first="Alexander N" last="Parkhomenko">Alexander N. Parkhomenko</name><affiliation><nlm:affiliation>Institute of Cardiology (Ukraine), Kiev, Ukraine.</nlm:affiliation></affiliation></author><author><name sortKey="Ertl, Georg" sort="Ertl, Georg" uniqKey="Ertl G" first="Georg" last="Ertl">Georg Ertl</name><affiliation><nlm:affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Stork, Stefan" sort="Stork, Stefan" uniqKey="Stork S" first="Stefan" last="Störk">Stefan Störk</name><affiliation><nlm:affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Keltai, Katalin" sort="Keltai, Katalin" uniqKey="Keltai K" first="Katalin" last="Keltai">Katalin Keltai</name><affiliation><nlm:affiliation>Semmelweis University, Budapest, Hungary.</nlm:affiliation></affiliation></author><author><name sortKey="Keltai, Matyas" sort="Keltai, Matyas" uniqKey="Keltai M" first="Matyas" last="Keltai">Matyas Keltai</name><affiliation><nlm:affiliation>Semmelweis University, Budapest, Hungary.</nlm:affiliation></affiliation></author><author><name sortKey="Ryden, Lars" sort="Ryden, Lars" uniqKey="Ryden L" first="Lars" last="Ryden">Lars Ryden</name><affiliation><nlm:affiliation>Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Dagenais, Gilles R" sort="Dagenais, Gilles R" uniqKey="Dagenais G" first="Gilles R" last="Dagenais">Gilles R. Dagenais</name><affiliation><nlm:affiliation>Institut Universitaire de Cardiologie et Pneumologie de Quebec, Quebec City, Quebec, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Pogosova, Nana" sort="Pogosova, Nana" uniqKey="Pogosova N" first="Nana" last="Pogosova">Nana Pogosova</name><affiliation><nlm:affiliation>National Research Centre for Preventative Medicine (Moscow), Moscow, Russia.</nlm:affiliation></affiliation></author><author><name sortKey="Dans, Antonio L" sort="Dans, Antonio L" uniqKey="Dans A" first="Antonio L" last="Dans">Antonio L. Dans</name><affiliation><nlm:affiliation>University of Philippines - Manila, Manila, The Philippines.</nlm:affiliation></affiliation></author><author><name sortKey="Lanas, Fernando" sort="Lanas, Fernando" uniqKey="Lanas F" first="Fernando" last="Lanas">Fernando Lanas</name><affiliation><nlm:affiliation>Universidad de La Frontera, Temuco, Chile.</nlm:affiliation></affiliation></author><author><name sortKey="Commerford, Patrick J" sort="Commerford, Patrick J" uniqKey="Commerford P" first="Patrick J" last="Commerford">Patrick J. Commerford</name><affiliation><nlm:affiliation>Division of Cardiology, Department of Medicine, University of Cape Town, Temuco, Chile.</nlm:affiliation></affiliation></author><author><name sortKey="Torp Pedersen, Christian" sort="Torp Pedersen, Christian" uniqKey="Torp Pedersen C" first="Christian" last="Torp-Pedersen">Christian Torp-Pedersen</name><affiliation><nlm:affiliation>University of Aalborg, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Guzik, Tomasz J" sort="Guzik, Tomasz J" uniqKey="Guzik T" first="Tomasz J" last="Guzik">Tomasz J. Guzik</name><affiliation><nlm:affiliation>Collegium Medicum Jagiellonian University, Krakow, Poland; University of Glasgow, Glasgow, Scotland, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Verhamme, Peter B" sort="Verhamme, Peter B" uniqKey="Verhamme P" first="Peter B" last="Verhamme">Peter B. Verhamme</name><affiliation><nlm:affiliation>University of Leuven, Flanders, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Vinereanu, Dragos" sort="Vinereanu, Dragos" uniqKey="Vinereanu D" first="Dragos" last="Vinereanu">Dragos Vinereanu</name><affiliation><nlm:affiliation>University of Medicine and Pharmacology Carol Davila University and Emergency Hospital, Bucharest, Romania.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Jae Hyung" sort="Kim, Jae Hyung" uniqKey="Kim J" first="Jae-Hyung" last="Kim">Jae-Hyung Kim</name><affiliation><nlm:affiliation>The Catholic University of Korea, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Ha, Jong Won" sort="Ha, Jong Won" uniqKey="Ha J" first="Jong-Won" last="Ha">Jong-Won Ha</name><affiliation><nlm:affiliation>Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Tonkin, Andrew M" sort="Tonkin, Andrew M" uniqKey="Tonkin A" first="Andrew M" last="Tonkin">Andrew M. Tonkin</name><affiliation><nlm:affiliation>Monash University, Melbourne, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Varigos, John D" sort="Varigos, John D" uniqKey="Varigos J" first="John D" last="Varigos">John D. Varigos</name><affiliation><nlm:affiliation>Monash University, Melbourne, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Lewis, Basil S" sort="Lewis, Basil S" uniqKey="Lewis B" first="Basil S" last="Lewis">Basil S. Lewis</name><affiliation><nlm:affiliation>Lady Davis Carmel Medical Centre, Haifa, Israel.</nlm:affiliation></affiliation></author><author><name sortKey="Felix, Camilo" sort="Felix, Camilo" uniqKey="Felix C" first="Camilo" last="Felix">Camilo Felix</name><affiliation><nlm:affiliation>Facultad de Ciencias de la Salud Eugenio Espejo UTE, Quito, Ecuador.</nlm:affiliation></affiliation></author><author><name sortKey="Yusoff, Khalid" sort="Yusoff, Khalid" uniqKey="Yusoff K" first="Khalid" last="Yusoff">Khalid Yusoff</name><affiliation><nlm:affiliation>Universiti Teknologi Mara, Selangor, Malaysia.</nlm:affiliation></affiliation></author><author><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name><affiliation><nlm:affiliation>Université Paris Diderot, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, FACT, DHU FIRE, INSERM U1148, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Aboyans, Victor" sort="Aboyans, Victor" uniqKey="Aboyans V" first="Victor" last="Aboyans">Victor Aboyans</name><affiliation><nlm:affiliation>Dupuytren University Hospital, Limoges, France.</nlm:affiliation></affiliation></author><author><name sortKey="Metsarinne, Kaj P" sort="Metsarinne, Kaj P" uniqKey="Metsarinne K" first="Kaj P" last="Metsarinne">Kaj P. Metsarinne</name><affiliation><nlm:affiliation>Turku University Central Hospital and Turku University, Turku, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Anand, Sonia S" sort="Anand, Sonia S" uniqKey="Anand S" first="Sonia S" last="Anand">Sonia S. Anand</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Hart, Robert G" sort="Hart, Robert G" uniqKey="Hart R" first="Robert G" last="Hart">Robert G. Hart</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Lamy, Andre" sort="Lamy, Andre" uniqKey="Lamy A" first="Andre" last="Lamy">Andre Lamy</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Moayyedi, Paul" sort="Moayyedi, Paul" uniqKey="Moayyedi P" first="Paul" last="Moayyedi">Paul Moayyedi</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Leong, Darryl P" sort="Leong, Darryl P" uniqKey="Leong D" first="Darryl P" last="Leong">Darryl P. Leong</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Sharma, Mukul" sort="Sharma, Mukul" uniqKey="Sharma M" first="Mukul" last="Sharma">Mukul Sharma</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Yusuf, Salim" sort="Yusuf, Salim" uniqKey="Yusuf S" first="Salim" last="Yusuf">Salim Yusuf</name><affiliation><nlm:affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</nlm:affiliation></affiliation></author></analytic><series><title level="j">The Canadian journal of cardiology</title><idno type="eISSN">1916-7075</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anticoagulants (therapeutic use)</term><term>Cardiovascular Diseases (prevention & control)</term><term>Humans</term><term>Practice Guidelines as Topic</term><term>Randomized Controlled Trials as Topic (methods)</term><term>Thrombolytic Therapy (standards)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anticoagulants</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Randomized Controlled Trials as Topic</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Cardiovascular Diseases</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Thrombolytic Therapy</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Practice Guidelines as Topic</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Long-term aspirin prevents vascular events but is only modestly effective. Rivaroxaban alone or in combination with aspirin might be more effective than aspirin alone for vascular prevention in patients with stable coronary artery disease (CAD) or peripheral artery disease (PAD). Rivaroxaban as well as aspirin increase upper gastrointestinal (GI) bleeding and this might be prevented by proton pump inhibitor therapy.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28754388</PMID><DateCreated><Year>2017</Year><Month>07</Month><Day>29</Day></DateCreated><DateCompleted><Year>2017</Year><Month>09</Month><Day>01</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>01</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1916-7075</ISSN><JournalIssue CitedMedium="Internet"><Volume>33</Volume><Issue>8</Issue><PubDate><Year>2017</Year><Month>Aug</Month></PubDate></JournalIssue><Title>The Canadian journal of cardiology</Title><ISOAbbreviation>Can J Cardiol</ISOAbbreviation></Journal><ArticleTitle>Rationale, Design and Baseline Characteristics of Participants in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) Trial.</ArticleTitle><Pagination><MedlinePgn>1027-1035</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0828-282X(17)30306-9</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.cjca.2017.06.001</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Long-term aspirin prevents vascular events but is only modestly effective. Rivaroxaban alone or in combination with aspirin might be more effective than aspirin alone for vascular prevention in patients with stable coronary artery disease (CAD) or peripheral artery disease (PAD). Rivaroxaban as well as aspirin increase upper gastrointestinal (GI) bleeding and this might be prevented by proton pump inhibitor therapy.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) is a double-blind superiority trial comparing rivaroxaban 2.5 mg twice daily combined with aspirin 100 mg once daily or rivaroxaban 5 mg twice daily vs aspirin 100 mg once daily for prevention of myocardial infarction, stroke, or cardiovascular death in patients with stable CAD or PAD. Patients not taking a proton pump inhibitor were also randomized, using a partial factorial design, to pantoprazole 40 mg once daily or placebo. The trial was designed to have at least 90% power to detect a 20% reduction in each of the rivaroxaban treatment arms compared with aspirin and to detect a 50% reduction in upper GI complications with pantoprazole compared with placebo.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Between February 2013 and May 2016, we recruited 27,395 participants from 602 centres in 33 countries; 17,598 participants were included in the pantoprazole vs placebo comparison. At baseline, the mean age was 68.2 years, 22.0% were female, 90.6% had CAD, and 27.3% had PAD.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">COMPASS will provide information on the efficacy and safety of rivaroxaban, alone or in combination with aspirin, in the long-term management of patients with stable CAD or PAD, and on the efficacy and safety of pantoprazole in preventing upper GI complications in patients receiving antithrombotic therapy.</AbstractText><CopyrightInformation>Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bosch</LastName><ForeName>Jackie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada. Electronic address: jackie.bosch@phri.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eikelboom</LastName><ForeName>John W</ForeName><Initials>JW</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Connolly</LastName><ForeName>Stuart J</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bruns</LastName><ForeName>Nancy Cook</ForeName><Initials>NC</Initials><AffiliationInfo><Affiliation>Bayer AG, Leverkusen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lanius</LastName><ForeName>Vivian</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Bayer AG, Leverkusen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yuan</LastName><ForeName>Fei</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Misselwitz</LastName><ForeName>Frank</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Bayer AG, Leverkusen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Edmond</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Bayer AG, Leverkusen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Diaz</LastName><ForeName>Rafael</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Estudios Clínicos Latino América and Instituto Cardiovascular de Rosario, Rosario, Argentina.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alings</LastName><ForeName>Marco</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Amphia Ziekenhuis and WCN, Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lonn</LastName><ForeName>Eva M</ForeName><Initials>EM</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Widimsky</LastName><ForeName>Petr</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Cardiocenter, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University Prague, Prague, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hori</LastName><ForeName>Masatsugu</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Osaka International Cancer Institute, Osaka, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Avezum</LastName><ForeName>Alvaro</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Piegas</LastName><ForeName>Leopoldo S</ForeName><Initials>LS</Initials><AffiliationInfo><Affiliation>University of Sao Paulo, Sao Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bhatt</LastName><ForeName>Deepak L</ForeName><Initials>DL</Initials><AffiliationInfo><Affiliation>Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Branch</LastName><ForeName>Kelley R H</ForeName><Initials>KRH</Initials><AffiliationInfo><Affiliation>University of Washington Medical Centre, Seattle, Washington, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Probstfield</LastName><ForeName>Jeffrey L</ForeName><Initials>JL</Initials><AffiliationInfo><Affiliation>University of Washington, Seattle, Washington, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liang</LastName><ForeName>Yan</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>FuWai Hospital, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Lisheng</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>FuWai Hospital, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhu</LastName><ForeName>Jun</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>FuWai Hospital, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maggioni</LastName><ForeName>Aldo P</ForeName><Initials>AP</Initials><AffiliationInfo><Affiliation>ANMCO Research Center, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lopez-Jaramillo</LastName><ForeName>Patricio</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Research Institute, FOSCAL-Bucaramanga, Bucaramanga, Colombia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Donnell</LastName><ForeName>Martin</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>National University of Ireland, Galway, Ireland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fox</LastName><ForeName>Keith A A</ForeName><Initials>KAA</Initials><AffiliationInfo><Affiliation>Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kakkar</LastName><ForeName>Ajay</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>University College London Hospitals, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Parkhomenko</LastName><ForeName>Alexander N</ForeName><Initials>AN</Initials><AffiliationInfo><Affiliation>Institute of Cardiology (Ukraine), Kiev, Ukraine.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ertl</LastName><ForeName>Georg</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Störk</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Comprehensive Heart Failure Center University and University Hospital Würzburg, Würzburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keltai</LastName><ForeName>Katalin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Semmelweis University, Budapest, Hungary.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keltai</LastName><ForeName>Matyas</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Semmelweis University, Budapest, Hungary.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ryden</LastName><ForeName>Lars</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dagenais</LastName><ForeName>Gilles R</ForeName><Initials>GR</Initials><AffiliationInfo><Affiliation>Institut Universitaire de Cardiologie et Pneumologie de Quebec, Quebec City, Quebec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pogosova</LastName><ForeName>Nana</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>National Research Centre for Preventative Medicine (Moscow), Moscow, Russia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dans</LastName><ForeName>Antonio L</ForeName><Initials>AL</Initials><AffiliationInfo><Affiliation>University of Philippines - Manila, Manila, The Philippines.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lanas</LastName><ForeName>Fernando</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Universidad de La Frontera, Temuco, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Commerford</LastName><ForeName>Patrick J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Division of Cardiology, Department of Medicine, University of Cape Town, Temuco, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Torp-Pedersen</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>University of Aalborg, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guzik</LastName><ForeName>Tomasz J</ForeName><Initials>TJ</Initials><AffiliationInfo><Affiliation>Collegium Medicum Jagiellonian University, Krakow, Poland; University of Glasgow, Glasgow, Scotland, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Verhamme</LastName><ForeName>Peter B</ForeName><Initials>PB</Initials><AffiliationInfo><Affiliation>University of Leuven, Flanders, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vinereanu</LastName><ForeName>Dragos</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>University of Medicine and Pharmacology Carol Davila University and Emergency Hospital, Bucharest, Romania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Jae-Hyung</ForeName><Initials>JH</Initials><AffiliationInfo><Affiliation>The Catholic University of Korea, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ha</LastName><ForeName>Jong-Won</ForeName><Initials>JW</Initials><AffiliationInfo><Affiliation>Yonsei University College of Medicine, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tonkin</LastName><ForeName>Andrew M</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Monash University, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Varigos</LastName><ForeName>John D</ForeName><Initials>JD</Initials><AffiliationInfo><Affiliation>Monash University, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lewis</LastName><ForeName>Basil S</ForeName><Initials>BS</Initials><AffiliationInfo><Affiliation>Lady Davis Carmel Medical Centre, Haifa, Israel.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Felix</LastName><ForeName>Camilo</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Facultad de Ciencias de la Salud Eugenio Espejo UTE, Quito, Ecuador.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yusoff</LastName><ForeName>Khalid</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Universiti Teknologi Mara, Selangor, Malaysia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Steg</LastName><ForeName>Philippe Gabriel</ForeName><Initials>PG</Initials><AffiliationInfo><Affiliation>Université Paris Diderot, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, FACT, DHU FIRE, INSERM U1148, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aboyans</LastName><ForeName>Victor</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Dupuytren University Hospital, Limoges, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Metsarinne</LastName><ForeName>Kaj P</ForeName><Initials>KP</Initials><AffiliationInfo><Affiliation>Turku University Central Hospital and Turku University, Turku, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Anand</LastName><ForeName>Sonia S</ForeName><Initials>SS</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hart</LastName><ForeName>Robert G</ForeName><Initials>RG</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lamy</LastName><ForeName>Andre</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moayyedi</LastName><ForeName>Paul</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Leong</LastName><ForeName>Darryl P</ForeName><Initials>DP</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sharma</LastName><ForeName>Mukul</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yusuf</LastName><ForeName>Salim</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>06</Month><Day>08</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Can J Cardiol</MedlineTA><NlmUniqueID>8510280</NlmUniqueID><ISSNLinking>0828-282X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000925">Anticoagulants</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000925" MajorTopicYN="N">Anticoagulants</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002318" MajorTopicYN="N">Cardiovascular Diseases</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017410" MajorTopicYN="Y">Practice Guidelines as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016032" MajorTopicYN="N">Randomized Controlled Trials as Topic</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015912" MajorTopicYN="N">Thrombolytic Therapy</DescriptorName><QualifierName UI="Q000592" MajorTopicYN="Y">standards</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>05</Month><Day>25</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>06</Month><Day>04</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>06</Month><Day>04</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>7</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>7</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>9</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28754388</ArticleId><ArticleId IdType="pii">S0828-282X(17)30306-9</ArticleId><ArticleId IdType="doi">10.1016/j.cjca.2017.06.001</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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