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Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.

Identifieur interne : 003378 ( PubMed/Corpus ); précédent : 003377; suivant : 003379

Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.

Auteurs : Christine F. Skibola ; Sonja I. Berndt ; Joseph Vijai ; Lucia Conde ; Zhaoming Wang ; Meredith Yeager ; Paul I W. De Bakker ; Brenda M. Birmann ; Claire M. Vajdic ; Jia-Nee Foo ; Paige M. Bracci ; Roel C H. Vermeulen ; Susan L. Slager ; Silvia De Sanjose ; Sophia S. Wang ; Martha S. Linet ; Gilles Salles ; Qing Lan ; Gianluca Severi ; Henrik Hjalgrim ; Tracy Lightfoot ; Mads Melbye ; Jian Gu ; Hervé Ghesquières ; Brian K. Link ; Lindsay M. Morton ; Elizabeth A. Holly ; Alex Smith ; Lesley F. Tinker ; Lauren R. Teras ; Anne Kricker ; Nikolaus Becker ; Mark P. Purdue ; John J. Spinelli ; Yawei Zhang ; Graham G. Giles ; Paolo Vineis ; Alain Monnereau ; Kimberly A. Bertrand ; Demetrius Albanes ; Anne Zeleniuch-Jacquotte ; Attilio Gabbas ; Charles C. Chung ; Laurie Burdett ; Amy Hutchinson ; Charles Lawrence ; Rebecca Montalvan ; Liming Liang ; Jinyan Huang ; Baoshan Ma ; Jianjun Liu ; Hans-Olov Adami ; Bengt Glimelius ; Yuanqing Ye ; Grzegorz S. Nowakowski ; Ahmet Dogan ; Carrie A. Thompson ; Thomas M. Habermann ; Anne J. Novak ; Mark Liebow ; Thomas E. Witzig ; George J. Weiner ; Maryjean Schenk ; Patricia Hartge ; Anneclaire J. De Roos ; Wendy Cozen ; Degui Zhi ; Nicholas K. Akers ; Jacques Riby ; Martyn T. Smith ; Mortimer Lacher ; Danylo J. Villano ; Ann Maria ; Eve Roman ; Eleanor Kane ; Rebecca D. Jackson ; Kari E. North ; W Ryan Diver ; Jenny Turner ; Bruce K. Armstrong ; Yolanda Benavente ; Paolo Boffetta ; Paul Brennan ; Lenka Foretova ; Marc Maynadie ; Anthony Staines ; James Mckay ; Angela R. Brooks-Wilson ; Tongzhang Zheng ; Theodore R. Holford ; Saioa Chamosa ; Rudolph Kaaks ; Rachel S. Kelly ; Bodil Ohlsson ; Ruth C. Travis ; Elisabete Weiderpass ; Jacqueline Clavel ; Edward Giovannucci ; Peter Kraft ; Jarmo Virtamo ; Patrizio Mazza ; Pierluigi Cocco ; Maria Grazia Ennas ; Brian C H. Chiu ; Joseph F. Fraumeni ; Alexandra Nieters ; Kenneth Offit ; Xifeng Wu ; James R. Cerhan ; Karin E. Smedby ; Stephen J. Chanock ; Nathaniel Rothman

Source :

RBID : pubmed:25279986

English descriptors

Abstract

Genome-wide association studies (GWASs) of follicular lymphoma (FL) have previously identified human leukocyte antigen (HLA) gene variants. To identify additional FL susceptibility loci, we conducted a large-scale two-stage GWAS in 4,523 case subjects and 13,344 control subjects of European ancestry. Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. In an analysis of the HLA region, we identified four linked HLA-DRβ1 multiallelic amino acids at positions 11, 13, 28, and 30 that were associated with FL risk (pomnibus = 4.20 × 10(-67) to 2.67 × 10(-70)). Additional independent signals included rs17203612 in HLA class II (odds ratio [OR(per-allele)] = 1.44; p = 4.59 × 10(-16)) and rs3130437 in HLA class I (OR(per-allele) = 1.23; p = 8.23 × 10(-9)). Our findings further expand the number of loci associated with FL and provide evidence that multiple common variants outside the HLA region make a significant contribution to FL risk.

DOI: 10.1016/j.ajhg.2014.09.004
PubMed: 25279986

Links to Exploration step

pubmed:25279986

Le document en format XML

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<nlm:affiliation>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center, Birmingham, AL 35233, USA; Division of Environmental Health Sciences, University of California Berkeley School of Public Health, Berkeley, CA 94720, USA. Electronic address: cskibola@uab.edu.</nlm:affiliation>
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<nlm:affiliation>Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</nlm:affiliation>
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<name sortKey="Conde, Lucia" sort="Conde, Lucia" uniqKey="Conde L" first="Lucia" last="Conde">Lucia Conde</name>
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<name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name>
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<nlm:affiliation>Department of Medical Genetics and of Epidemiology, University Medical Center Utrecht, Utrecht 3584 CG, the Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht 3584 CX, the Netherlands.</nlm:affiliation>
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<name sortKey="Vajdic, Claire M" sort="Vajdic, Claire M" uniqKey="Vajdic C" first="Claire M" last="Vajdic">Claire M. Vajdic</name>
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<name sortKey="Foo, Jia Nee" sort="Foo, Jia Nee" uniqKey="Foo J" first="Jia-Nee" last="Foo">Jia-Nee Foo</name>
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<name sortKey="Bracci, Paige M" sort="Bracci, Paige M" uniqKey="Bracci P" first="Paige M" last="Bracci">Paige M. Bracci</name>
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<nlm:affiliation>Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA 94118, USA.</nlm:affiliation>
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<name sortKey="Vermeulen, Roel C H" sort="Vermeulen, Roel C H" uniqKey="Vermeulen R" first="Roel C H" last="Vermeulen">Roel C H. Vermeulen</name>
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<nlm:affiliation>Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht 3584 CX, the Netherlands; Institute for Risk Assessment Sciences, Utrecht University, Utrecht 3508 TD, the Netherlands.</nlm:affiliation>
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<name sortKey="Slager, Susan L" sort="Slager, Susan L" uniqKey="Slager S" first="Susan L" last="Slager">Susan L. Slager</name>
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<nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
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<nlm:affiliation>Unit of Infections and Cancer (UNIC), Cancer Epidemiology Research Programme, Institut Catala d'Oncologia, IDIBELL, Barcelona 8907, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Barcelona 8036, Spain.</nlm:affiliation>
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<name sortKey="Wang, Sophia S" sort="Wang, Sophia S" uniqKey="Wang S" first="Sophia S" last="Wang">Sophia S. Wang</name>
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<nlm:affiliation>Department of Cancer Etiology, City of Hope Beckman Research Institute, Duarte, CA 91030, USA.</nlm:affiliation>
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<name sortKey="Linet, Martha S" sort="Linet, Martha S" uniqKey="Linet M" first="Martha S" last="Linet">Martha S. Linet</name>
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<name sortKey="Salles, Gilles" sort="Salles, Gilles" uniqKey="Salles G" first="Gilles" last="Salles">Gilles Salles</name>
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<nlm:affiliation>Department of Hematology, Hospices Civils de Lyon, Pierre benite Cedex 69495, France; Department of Hematology, Université Lyon-1, Pierre benite Cedex 69495, France; Laboratoire de Biologie Moléculaire de la Cellule UMR 5239, Centre National de la Recherche Scientifique, Pierre benite Cedex 69495, France.</nlm:affiliation>
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<name sortKey="Lan, Qing" sort="Lan, Qing" uniqKey="Lan Q" first="Qing" last="Lan">Qing Lan</name>
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<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
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<name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name>
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<nlm:affiliation>Human Genetics Foundation, Turin 10126, Italy; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC 3053, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Carlton, VIC 3010, Australia.</nlm:affiliation>
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<nlm:affiliation>Department of Epidemiology Research, Division of Health Surveillance and Research, Statens Serum Institut, Copenhagen 2300, Denmark.</nlm:affiliation>
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<name sortKey="Lightfoot, Tracy" sort="Lightfoot, Tracy" uniqKey="Lightfoot T" first="Tracy" last="Lightfoot">Tracy Lightfoot</name>
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<nlm:affiliation>Department of Health Sciences, University of York, York YO10 5DD, UK.</nlm:affiliation>
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<name sortKey="Melbye, Mads" sort="Melbye, Mads" uniqKey="Melbye M" first="Mads" last="Melbye">Mads Melbye</name>
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<nlm:affiliation>Department of Epidemiology Research, Division of Health Surveillance and Research, Statens Serum Institut, Copenhagen 2300, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.</nlm:affiliation>
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<name sortKey="Gu, Jian" sort="Gu, Jian" uniqKey="Gu J" first="Jian" last="Gu">Jian Gu</name>
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<nlm:affiliation>Department of Epidemiology, M.D. Anderson Cancer Center, Houston, TX 77030, USA.</nlm:affiliation>
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<name sortKey="Ghesquieres, Herve" sort="Ghesquieres, Herve" uniqKey="Ghesquieres H" first="Hervé" last="Ghesquières">Hervé Ghesquières</name>
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<nlm:affiliation>Laboratoire de Biologie Moléculaire de la Cellule UMR 5239, Centre National de la Recherche Scientifique, Pierre benite Cedex 69495, France; Department of Hematology, Centre Léon Bérard, Lyon 69008, France.</nlm:affiliation>
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<name sortKey="Link, Brian K" sort="Link, Brian K" uniqKey="Link B" first="Brian K" last="Link">Brian K. Link</name>
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<nlm:affiliation>Department of Internal Medicine, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA.</nlm:affiliation>
</affiliation>
</author>
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<name sortKey="Morton, Lindsay M" sort="Morton, Lindsay M" uniqKey="Morton L" first="Lindsay M" last="Morton">Lindsay M. Morton</name>
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<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
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<name sortKey="Holly, Elizabeth A" sort="Holly, Elizabeth A" uniqKey="Holly E" first="Elizabeth A" last="Holly">Elizabeth A. Holly</name>
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<nlm:affiliation>Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA 94118, USA.</nlm:affiliation>
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<name sortKey="Smith, Alex" sort="Smith, Alex" uniqKey="Smith A" first="Alex" last="Smith">Alex Smith</name>
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<nlm:affiliation>Department of Health Sciences, University of York, York YO10 5DD, UK.</nlm:affiliation>
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<name sortKey="Tinker, Lesley F" sort="Tinker, Lesley F" uniqKey="Tinker L" first="Lesley F" last="Tinker">Lesley F. Tinker</name>
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<nlm:affiliation>Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98117, USA.</nlm:affiliation>
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<name sortKey="Teras, Lauren R" sort="Teras, Lauren R" uniqKey="Teras L" first="Lauren R" last="Teras">Lauren R. Teras</name>
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<nlm:affiliation>Epidemiology Research Program, American Cancer Society, Atlanta, GA 30303, USA.</nlm:affiliation>
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<author>
<name sortKey="Kricker, Anne" sort="Kricker, Anne" uniqKey="Kricker A" first="Anne" last="Kricker">Anne Kricker</name>
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<nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, NSW 2006, Australia.</nlm:affiliation>
</affiliation>
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<author>
<name sortKey="Becker, Nikolaus" sort="Becker, Nikolaus" uniqKey="Becker N" first="Nikolaus" last="Becker">Nikolaus Becker</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Baden-Württemberg 69120, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P" last="Purdue">Mark P. Purdue</name>
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<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
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<author>
<name sortKey="Spinelli, John J" sort="Spinelli, John J" uniqKey="Spinelli J" first="John J" last="Spinelli">John J. Spinelli</name>
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<nlm:affiliation>Cancer Control Research, BC Cancer Agency, Vancouver, BC V5Z 1L3, Canada; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zhang, Yawei" sort="Zhang, Yawei" uniqKey="Zhang Y" first="Yawei" last="Zhang">Yawei Zhang</name>
<affiliation>
<nlm:affiliation>Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT 06520, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name>
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<nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC 3053, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Carlton, VIC 3010, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name>
<affiliation>
<nlm:affiliation>Human Genetics Foundation, Turin 10126, Italy; MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Monnereau, Alain" sort="Monnereau, Alain" uniqKey="Monnereau A" first="Alain" last="Monnereau">Alain Monnereau</name>
<affiliation>
<nlm:affiliation>Environmental Epidemiology of Cancer Group, Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Villejuif Cedex 94807, France; UMRS 1018, Université Paris Sud, Villejuif Cedex 94807, France; Registre des hémopathies malignes de la Gironde, Institut Bergonié, Bordeaux Cedex 33076, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Bertrand, Kimberly A" sort="Bertrand, Kimberly A" uniqKey="Bertrand K" first="Kimberly A" last="Bertrand">Kimberly A. Bertrand</name>
<affiliation>
<nlm:affiliation>Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name>
<affiliation>
<nlm:affiliation>Department of Population Health, New York University School of Medicine, New York, NY 10016, USA; Cancer Institute, New York University School of Medicine, New York, NY 10016, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Gabbas, Attilio" sort="Gabbas, Attilio" uniqKey="Gabbas A" first="Attilio" last="Gabbas">Attilio Gabbas</name>
<affiliation>
<nlm:affiliation>Department of Public Health, Clinical and Molecular Medicine, University of Cagliari, Monserrato, Cagliari 09042, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chung, Charles C" sort="Chung, Charles C" uniqKey="Chung C" first="Charles C" last="Chung">Charles C. Chung</name>
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<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Burdett, Laurie" sort="Burdett, Laurie" uniqKey="Burdett L" first="Laurie" last="Burdett">Laurie Burdett</name>
<affiliation>
<nlm:affiliation>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Gaithersburg, MD 20877, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hutchinson, Amy" sort="Hutchinson, Amy" uniqKey="Hutchinson A" first="Amy" last="Hutchinson">Amy Hutchinson</name>
<affiliation>
<nlm:affiliation>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Gaithersburg, MD 20877, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lawrence, Charles" sort="Lawrence, Charles" uniqKey="Lawrence C" first="Charles" last="Lawrence">Charles Lawrence</name>
<affiliation>
<nlm:affiliation>Health Studies Sector, Westat, Rockville, MD 20850, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Montalvan, Rebecca" sort="Montalvan, Rebecca" uniqKey="Montalvan R" first="Rebecca" last="Montalvan">Rebecca Montalvan</name>
<affiliation>
<nlm:affiliation>Health Studies Sector, Westat, Rockville, MD 20850, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Liang, Liming" sort="Liang, Liming" uniqKey="Liang L" first="Liming" last="Liang">Liming Liang</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA; Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Huang, Jinyan" sort="Huang, Jinyan" uniqKey="Huang J" first="Jinyan" last="Huang">Jinyan Huang</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ma, Baoshan" sort="Ma, Baoshan" uniqKey="Ma B" first="Baoshan" last="Ma">Baoshan Ma</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA; College of Information Science and Technology, Dalian Maritime University, Dalian, Liaoning Province 116026, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name>
<affiliation>
<nlm:affiliation>Human Genetics, Genome Institute of Singapore, Singapore 138672, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Adami, Hans Olov" sort="Adami, Hans Olov" uniqKey="Adami H" first="Hans-Olov" last="Adami">Hans-Olov Adami</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Glimelius, Bengt" sort="Glimelius, Bengt" uniqKey="Glimelius B" first="Bengt" last="Glimelius">Bengt Glimelius</name>
<affiliation>
<nlm:affiliation>Department of Oncology and Pathology, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm 17176, Sweden; Department of Radiology, Oncology and Radiation Science, Uppsala University, Uppsala 75105, Sweden.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ye, Yuanqing" sort="Ye, Yuanqing" uniqKey="Ye Y" first="Yuanqing" last="Ye">Yuanqing Ye</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, M.D. Anderson Cancer Center, Houston, TX 77030, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Nowakowski, Grzegorz S" sort="Nowakowski, Grzegorz S" uniqKey="Nowakowski G" first="Grzegorz S" last="Nowakowski">Grzegorz S. Nowakowski</name>
<affiliation>
<nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Dogan, Ahmet" sort="Dogan, Ahmet" uniqKey="Dogan A" first="Ahmet" last="Dogan">Ahmet Dogan</name>
<affiliation>
<nlm:affiliation>Departments of Laboratory Medicine and Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Thompson, Carrie A" sort="Thompson, Carrie A" uniqKey="Thompson C" first="Carrie A" last="Thompson">Carrie A. Thompson</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Habermann, Thomas M" sort="Habermann, Thomas M" uniqKey="Habermann T" first="Thomas M" last="Habermann">Thomas M. Habermann</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Novak, Anne J" sort="Novak, Anne J" uniqKey="Novak A" first="Anne J" last="Novak">Anne J. Novak</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Liebow, Mark" sort="Liebow, Mark" uniqKey="Liebow M" first="Mark" last="Liebow">Mark Liebow</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Witzig, Thomas E" sort="Witzig, Thomas E" uniqKey="Witzig T" first="Thomas E" last="Witzig">Thomas E. Witzig</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Weiner, George J" sort="Weiner, George J" uniqKey="Weiner G" first="George J" last="Weiner">George J. Weiner</name>
<affiliation>
<nlm:affiliation>Department of Internal Medicine, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Schenk, Maryjean" sort="Schenk, Maryjean" uniqKey="Schenk M" first="Maryjean" last="Schenk">Maryjean Schenk</name>
<affiliation>
<nlm:affiliation>Department of Family Medicine and Public Health Sciences, Wayne State University, Detroit, MI 48201, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="De Roos, Anneclaire J" sort="De Roos, Anneclaire J" uniqKey="De Roos A" first="Anneclaire J" last="De Roos">Anneclaire J. De Roos</name>
<affiliation>
<nlm:affiliation>Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98117, USA; Department of Environmental and Occupational Health, Drexel University School of Public Health, Philadelphia, PA 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Cozen, Wendy" sort="Cozen, Wendy" uniqKey="Cozen W" first="Wendy" last="Cozen">Wendy Cozen</name>
<affiliation>
<nlm:affiliation>Department of Preventive Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Norris Comprehensive Cancer Center, USC Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zhi, Degui" sort="Zhi, Degui" uniqKey="Zhi D" first="Degui" last="Zhi">Degui Zhi</name>
<affiliation>
<nlm:affiliation>Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35233, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Akers, Nicholas K" sort="Akers, Nicholas K" uniqKey="Akers N" first="Nicholas K" last="Akers">Nicholas K. Akers</name>
<affiliation>
<nlm:affiliation>Division of Environmental Health Sciences, University of California Berkeley School of Public Health, Berkeley, CA 94720, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Riby, Jacques" sort="Riby, Jacques" uniqKey="Riby J" first="Jacques" last="Riby">Jacques Riby</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center, Birmingham, AL 35233, USA; Division of Environmental Health Sciences, University of California Berkeley School of Public Health, Berkeley, CA 94720, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Smith, Martyn T" sort="Smith, Martyn T" uniqKey="Smith M" first="Martyn T" last="Smith">Martyn T. Smith</name>
<affiliation>
<nlm:affiliation>Division of Environmental Health Sciences, University of California Berkeley School of Public Health, Berkeley, CA 94720, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lacher, Mortimer" sort="Lacher, Mortimer" uniqKey="Lacher M" first="Mortimer" last="Lacher">Mortimer Lacher</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Villano, Danylo J" sort="Villano, Danylo J" uniqKey="Villano D" first="Danylo J" last="Villano">Danylo J. Villano</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Maria, Ann" sort="Maria, Ann" uniqKey="Maria A" first="Ann" last="Maria">Ann Maria</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Roman, Eve" sort="Roman, Eve" uniqKey="Roman E" first="Eve" last="Roman">Eve Roman</name>
<affiliation>
<nlm:affiliation>Department of Health Sciences, University of York, York YO10 5DD, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kane, Eleanor" sort="Kane, Eleanor" uniqKey="Kane E" first="Eleanor" last="Kane">Eleanor Kane</name>
<affiliation>
<nlm:affiliation>Department of Health Sciences, University of York, York YO10 5DD, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Jackson, Rebecca D" sort="Jackson, Rebecca D" uniqKey="Jackson R" first="Rebecca D" last="Jackson">Rebecca D. Jackson</name>
<affiliation>
<nlm:affiliation>Division of Endocrinology, Diabetes and Metabolism, The Ohio State University, Columbus, OH 43210, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E" last="North">Kari E. North</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Diver, W Ryan" sort="Diver, W Ryan" uniqKey="Diver W" first="W Ryan" last="Diver">W Ryan Diver</name>
<affiliation>
<nlm:affiliation>Epidemiology Research Program, American Cancer Society, Atlanta, GA 30303, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Turner, Jenny" sort="Turner, Jenny" uniqKey="Turner J" first="Jenny" last="Turner">Jenny Turner</name>
<affiliation>
<nlm:affiliation>Department of Anatomical Pathology, Australian School of Advanced Medicine, Macquarie University, Sydney, NSW 2109, Australia; Department of Histopathology, Douglass Hanly Moir Pathology, Macquarie Park, NSW 2113, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Armstrong, Bruce K" sort="Armstrong, Bruce K" uniqKey="Armstrong B" first="Bruce K" last="Armstrong">Bruce K. Armstrong</name>
<affiliation>
<nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, NSW 2006, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Benavente, Yolanda" sort="Benavente, Yolanda" uniqKey="Benavente Y" first="Yolanda" last="Benavente">Yolanda Benavente</name>
<affiliation>
<nlm:affiliation>Unit of Infections and Cancer (UNIC), Cancer Epidemiology Research Programme, Institut Catala d'Oncologia, IDIBELL, Barcelona 8907, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Barcelona 8036, Spain.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Boffetta, Paolo" sort="Boffetta, Paolo" uniqKey="Boffetta P" first="Paolo" last="Boffetta">Paolo Boffetta</name>
<affiliation>
<nlm:affiliation>The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name>
<affiliation>
<nlm:affiliation>Group of Genetic Epidemiology, Section of Genetics, International Agency for Research on Cancer, Lyon 69372, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name>
<affiliation>
<nlm:affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute and MF MU, Brno 656 53, Czech Republic.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Maynadie, Marc" sort="Maynadie, Marc" uniqKey="Maynadie M" first="Marc" last="Maynadie">Marc Maynadie</name>
<affiliation>
<nlm:affiliation>EA 4184, Registre des Hémopathies Malignes de Côte d'Or, University of Burgundy and Dijon University Hospital, Dijon 21070, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Staines, Anthony" sort="Staines, Anthony" uniqKey="Staines A" first="Anthony" last="Staines">Anthony Staines</name>
<affiliation>
<nlm:affiliation>School of Nursing and Human Sciences, Dublin City University, Dublin 9, Ireland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mckay, James" sort="Mckay, James" uniqKey="Mckay J" first="James" last="Mckay">James Mckay</name>
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<nlm:affiliation>Genetic Cancer Susceptibility Group, Section of Genetics, International Agency for Research on Cancer, Lyon 69372, France.</nlm:affiliation>
</affiliation>
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<name sortKey="Brooks Wilson, Angela R" sort="Brooks Wilson, Angela R" uniqKey="Brooks Wilson A" first="Angela R" last="Brooks-Wilson">Angela R. Brooks-Wilson</name>
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<nlm:affiliation>Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 1L3, Canada; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.</nlm:affiliation>
</affiliation>
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<name sortKey="Zheng, Tongzhang" sort="Zheng, Tongzhang" uniqKey="Zheng T" first="Tongzhang" last="Zheng">Tongzhang Zheng</name>
<affiliation>
<nlm:affiliation>Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT 06520, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Holford, Theodore R" sort="Holford, Theodore R" uniqKey="Holford T" first="Theodore R" last="Holford">Theodore R. Holford</name>
<affiliation>
<nlm:affiliation>Department of Biostatistics, Yale School of Public Health, New Haven, CT 06520, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chamosa, Saioa" sort="Chamosa, Saioa" uniqKey="Chamosa S" first="Saioa" last="Chamosa">Saioa Chamosa</name>
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<nlm:affiliation>Health Department, BioDonostia Research Institute, Basque Region 20014, Spain.</nlm:affiliation>
</affiliation>
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<author>
<name sortKey="Kaaks, Rudolph" sort="Kaaks, Rudolph" uniqKey="Kaaks R" first="Rudolph" last="Kaaks">Rudolph Kaaks</name>
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<nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Baden-Württemberg 69120, Germany.</nlm:affiliation>
</affiliation>
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<name sortKey="Kelly, Rachel S" sort="Kelly, Rachel S" uniqKey="Kelly R" first="Rachel S" last="Kelly">Rachel S. Kelly</name>
<affiliation>
<nlm:affiliation>MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
</affiliation>
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<name sortKey="Ohlsson, Bodil" sort="Ohlsson, Bodil" uniqKey="Ohlsson B" first="Bodil" last="Ohlsson">Bodil Ohlsson</name>
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<nlm:affiliation>Department of Clinical Sciences, Division of Internal Medicine, Skåne University Hospital, Lund University, Malmö 205 02, Sweden.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C" last="Travis">Ruth C. Travis</name>
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<nlm:affiliation>Cancer Epidemiology Unit, University of Oxford, Oxford OX3 7LF, UK.</nlm:affiliation>
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<name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
<affiliation>
<nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Breivika 9037, Norway; Cancer Registry of Norway, Oslo 0304, Norway; Department of Genetic Epidemiology, Folkhalsan Research Center, Helsinki 00250, Finland.</nlm:affiliation>
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<name sortKey="Clavel, Jacqueline" sort="Clavel, Jacqueline" uniqKey="Clavel J" first="Jacqueline" last="Clavel">Jacqueline Clavel</name>
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<nlm:affiliation>Environmental Epidemiology of Cancer Group, Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Villejuif Cedex 94807, France; UMRS 1018, Université Paris Sud, Villejuif Cedex 94807, France.</nlm:affiliation>
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<name sortKey="Giovannucci, Edward" sort="Giovannucci, Edward" uniqKey="Giovannucci E" first="Edward" last="Giovannucci">Edward Giovannucci</name>
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<nlm:affiliation>Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA; Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
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<name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name>
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<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA; Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
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<name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name>
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<nlm:affiliation>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki 00271, Finland.</nlm:affiliation>
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<name sortKey="Mazza, Patrizio" sort="Mazza, Patrizio" uniqKey="Mazza P" first="Patrizio" last="Mazza">Patrizio Mazza</name>
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<nlm:affiliation>Department of Hematology, Ospedale Nord, Taranto 74100, Italy.</nlm:affiliation>
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<name sortKey="Cocco, Pierluigi" sort="Cocco, Pierluigi" uniqKey="Cocco P" first="Pierluigi" last="Cocco">Pierluigi Cocco</name>
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<nlm:affiliation>Department of Public Health, Clinical and Molecular Medicine, University of Cagliari, Monserrato, Cagliari 09042, Italy.</nlm:affiliation>
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<name sortKey="Ennas, Maria Grazia" sort="Ennas, Maria Grazia" uniqKey="Ennas M" first="Maria Grazia" last="Ennas">Maria Grazia Ennas</name>
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<nlm:affiliation>Department of Biomedical Science, University of Cagliari, Monserrato, Cagliari 09042, Italy.</nlm:affiliation>
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<name sortKey="Chiu, Brian C H" sort="Chiu, Brian C H" uniqKey="Chiu B" first="Brian C H" last="Chiu">Brian C H. Chiu</name>
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<nlm:affiliation>Department of Health Studies, University of Chicago, Chicago, IL 60637, USA.</nlm:affiliation>
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<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
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<nlm:affiliation>Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</nlm:affiliation>
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<name sortKey="Wu, Xifeng" sort="Wu, Xifeng" uniqKey="Wu X" first="Xifeng" last="Wu">Xifeng Wu</name>
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<name sortKey="Cerhan, James R" sort="Cerhan, James R" uniqKey="Cerhan J" first="James R" last="Cerhan">James R. Cerhan</name>
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<nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
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<nlm:affiliation>Department of Medicine Solna, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:affiliation>
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<name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name>
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<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
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<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
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<nlm:affiliation>Department of Medical Genetics and of Epidemiology, University Medical Center Utrecht, Utrecht 3584 CG, the Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht 3584 CX, the Netherlands.</nlm:affiliation>
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<nlm:affiliation>Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA 94118, USA.</nlm:affiliation>
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<nlm:affiliation>Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht 3584 CX, the Netherlands; Institute for Risk Assessment Sciences, Utrecht University, Utrecht 3508 TD, the Netherlands.</nlm:affiliation>
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<nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
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<name sortKey="De Sanjose, Silvia" sort="De Sanjose, Silvia" uniqKey="De Sanjose S" first="Silvia" last="De Sanjose">Silvia De Sanjose</name>
<affiliation>
<nlm:affiliation>Unit of Infections and Cancer (UNIC), Cancer Epidemiology Research Programme, Institut Catala d'Oncologia, IDIBELL, Barcelona 8907, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Barcelona 8036, Spain.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wang, Sophia S" sort="Wang, Sophia S" uniqKey="Wang S" first="Sophia S" last="Wang">Sophia S. Wang</name>
<affiliation>
<nlm:affiliation>Department of Cancer Etiology, City of Hope Beckman Research Institute, Duarte, CA 91030, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Linet, Martha S" sort="Linet, Martha S" uniqKey="Linet M" first="Martha S" last="Linet">Martha S. Linet</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Salles, Gilles" sort="Salles, Gilles" uniqKey="Salles G" first="Gilles" last="Salles">Gilles Salles</name>
<affiliation>
<nlm:affiliation>Department of Hematology, Hospices Civils de Lyon, Pierre benite Cedex 69495, France; Department of Hematology, Université Lyon-1, Pierre benite Cedex 69495, France; Laboratoire de Biologie Moléculaire de la Cellule UMR 5239, Centre National de la Recherche Scientifique, Pierre benite Cedex 69495, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lan, Qing" sort="Lan, Qing" uniqKey="Lan Q" first="Qing" last="Lan">Qing Lan</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name>
<affiliation>
<nlm:affiliation>Human Genetics Foundation, Turin 10126, Italy; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC 3053, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Carlton, VIC 3010, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hjalgrim, Henrik" sort="Hjalgrim, Henrik" uniqKey="Hjalgrim H" first="Henrik" last="Hjalgrim">Henrik Hjalgrim</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology Research, Division of Health Surveillance and Research, Statens Serum Institut, Copenhagen 2300, Denmark.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lightfoot, Tracy" sort="Lightfoot, Tracy" uniqKey="Lightfoot T" first="Tracy" last="Lightfoot">Tracy Lightfoot</name>
<affiliation>
<nlm:affiliation>Department of Health Sciences, University of York, York YO10 5DD, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Melbye, Mads" sort="Melbye, Mads" uniqKey="Melbye M" first="Mads" last="Melbye">Mads Melbye</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology Research, Division of Health Surveillance and Research, Statens Serum Institut, Copenhagen 2300, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Gu, Jian" sort="Gu, Jian" uniqKey="Gu J" first="Jian" last="Gu">Jian Gu</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, M.D. Anderson Cancer Center, Houston, TX 77030, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ghesquieres, Herve" sort="Ghesquieres, Herve" uniqKey="Ghesquieres H" first="Hervé" last="Ghesquières">Hervé Ghesquières</name>
<affiliation>
<nlm:affiliation>Laboratoire de Biologie Moléculaire de la Cellule UMR 5239, Centre National de la Recherche Scientifique, Pierre benite Cedex 69495, France; Department of Hematology, Centre Léon Bérard, Lyon 69008, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Link, Brian K" sort="Link, Brian K" uniqKey="Link B" first="Brian K" last="Link">Brian K. Link</name>
<affiliation>
<nlm:affiliation>Department of Internal Medicine, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Morton, Lindsay M" sort="Morton, Lindsay M" uniqKey="Morton L" first="Lindsay M" last="Morton">Lindsay M. Morton</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Holly, Elizabeth A" sort="Holly, Elizabeth A" uniqKey="Holly E" first="Elizabeth A" last="Holly">Elizabeth A. Holly</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA 94118, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Smith, Alex" sort="Smith, Alex" uniqKey="Smith A" first="Alex" last="Smith">Alex Smith</name>
<affiliation>
<nlm:affiliation>Department of Health Sciences, University of York, York YO10 5DD, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Tinker, Lesley F" sort="Tinker, Lesley F" uniqKey="Tinker L" first="Lesley F" last="Tinker">Lesley F. Tinker</name>
<affiliation>
<nlm:affiliation>Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98117, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Teras, Lauren R" sort="Teras, Lauren R" uniqKey="Teras L" first="Lauren R" last="Teras">Lauren R. Teras</name>
<affiliation>
<nlm:affiliation>Epidemiology Research Program, American Cancer Society, Atlanta, GA 30303, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kricker, Anne" sort="Kricker, Anne" uniqKey="Kricker A" first="Anne" last="Kricker">Anne Kricker</name>
<affiliation>
<nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, NSW 2006, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Becker, Nikolaus" sort="Becker, Nikolaus" uniqKey="Becker N" first="Nikolaus" last="Becker">Nikolaus Becker</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Baden-Württemberg 69120, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P" last="Purdue">Mark P. Purdue</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Spinelli, John J" sort="Spinelli, John J" uniqKey="Spinelli J" first="John J" last="Spinelli">John J. Spinelli</name>
<affiliation>
<nlm:affiliation>Cancer Control Research, BC Cancer Agency, Vancouver, BC V5Z 1L3, Canada; School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zhang, Yawei" sort="Zhang, Yawei" uniqKey="Zhang Y" first="Yawei" last="Zhang">Yawei Zhang</name>
<affiliation>
<nlm:affiliation>Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT 06520, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name>
<affiliation>
<nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC 3053, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Carlton, VIC 3010, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name>
<affiliation>
<nlm:affiliation>Human Genetics Foundation, Turin 10126, Italy; MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Monnereau, Alain" sort="Monnereau, Alain" uniqKey="Monnereau A" first="Alain" last="Monnereau">Alain Monnereau</name>
<affiliation>
<nlm:affiliation>Environmental Epidemiology of Cancer Group, Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Villejuif Cedex 94807, France; UMRS 1018, Université Paris Sud, Villejuif Cedex 94807, France; Registre des hémopathies malignes de la Gironde, Institut Bergonié, Bordeaux Cedex 33076, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Bertrand, Kimberly A" sort="Bertrand, Kimberly A" uniqKey="Bertrand K" first="Kimberly A" last="Bertrand">Kimberly A. Bertrand</name>
<affiliation>
<nlm:affiliation>Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name>
<affiliation>
<nlm:affiliation>Department of Population Health, New York University School of Medicine, New York, NY 10016, USA; Cancer Institute, New York University School of Medicine, New York, NY 10016, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Gabbas, Attilio" sort="Gabbas, Attilio" uniqKey="Gabbas A" first="Attilio" last="Gabbas">Attilio Gabbas</name>
<affiliation>
<nlm:affiliation>Department of Public Health, Clinical and Molecular Medicine, University of Cagliari, Monserrato, Cagliari 09042, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chung, Charles C" sort="Chung, Charles C" uniqKey="Chung C" first="Charles C" last="Chung">Charles C. Chung</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Burdett, Laurie" sort="Burdett, Laurie" uniqKey="Burdett L" first="Laurie" last="Burdett">Laurie Burdett</name>
<affiliation>
<nlm:affiliation>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Gaithersburg, MD 20877, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hutchinson, Amy" sort="Hutchinson, Amy" uniqKey="Hutchinson A" first="Amy" last="Hutchinson">Amy Hutchinson</name>
<affiliation>
<nlm:affiliation>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Gaithersburg, MD 20877, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lawrence, Charles" sort="Lawrence, Charles" uniqKey="Lawrence C" first="Charles" last="Lawrence">Charles Lawrence</name>
<affiliation>
<nlm:affiliation>Health Studies Sector, Westat, Rockville, MD 20850, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Montalvan, Rebecca" sort="Montalvan, Rebecca" uniqKey="Montalvan R" first="Rebecca" last="Montalvan">Rebecca Montalvan</name>
<affiliation>
<nlm:affiliation>Health Studies Sector, Westat, Rockville, MD 20850, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Liang, Liming" sort="Liang, Liming" uniqKey="Liang L" first="Liming" last="Liang">Liming Liang</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA; Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Huang, Jinyan" sort="Huang, Jinyan" uniqKey="Huang J" first="Jinyan" last="Huang">Jinyan Huang</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ma, Baoshan" sort="Ma, Baoshan" uniqKey="Ma B" first="Baoshan" last="Ma">Baoshan Ma</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA; College of Information Science and Technology, Dalian Maritime University, Dalian, Liaoning Province 116026, China.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name>
<affiliation>
<nlm:affiliation>Human Genetics, Genome Institute of Singapore, Singapore 138672, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Adami, Hans Olov" sort="Adami, Hans Olov" uniqKey="Adami H" first="Hans-Olov" last="Adami">Hans-Olov Adami</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Glimelius, Bengt" sort="Glimelius, Bengt" uniqKey="Glimelius B" first="Bengt" last="Glimelius">Bengt Glimelius</name>
<affiliation>
<nlm:affiliation>Department of Oncology and Pathology, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm 17176, Sweden; Department of Radiology, Oncology and Radiation Science, Uppsala University, Uppsala 75105, Sweden.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ye, Yuanqing" sort="Ye, Yuanqing" uniqKey="Ye Y" first="Yuanqing" last="Ye">Yuanqing Ye</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, M.D. Anderson Cancer Center, Houston, TX 77030, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Nowakowski, Grzegorz S" sort="Nowakowski, Grzegorz S" uniqKey="Nowakowski G" first="Grzegorz S" last="Nowakowski">Grzegorz S. Nowakowski</name>
<affiliation>
<nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Dogan, Ahmet" sort="Dogan, Ahmet" uniqKey="Dogan A" first="Ahmet" last="Dogan">Ahmet Dogan</name>
<affiliation>
<nlm:affiliation>Departments of Laboratory Medicine and Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Thompson, Carrie A" sort="Thompson, Carrie A" uniqKey="Thompson C" first="Carrie A" last="Thompson">Carrie A. Thompson</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Habermann, Thomas M" sort="Habermann, Thomas M" uniqKey="Habermann T" first="Thomas M" last="Habermann">Thomas M. Habermann</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Novak, Anne J" sort="Novak, Anne J" uniqKey="Novak A" first="Anne J" last="Novak">Anne J. Novak</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Liebow, Mark" sort="Liebow, Mark" uniqKey="Liebow M" first="Mark" last="Liebow">Mark Liebow</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Witzig, Thomas E" sort="Witzig, Thomas E" uniqKey="Witzig T" first="Thomas E" last="Witzig">Thomas E. Witzig</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Weiner, George J" sort="Weiner, George J" uniqKey="Weiner G" first="George J" last="Weiner">George J. Weiner</name>
<affiliation>
<nlm:affiliation>Department of Internal Medicine, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Schenk, Maryjean" sort="Schenk, Maryjean" uniqKey="Schenk M" first="Maryjean" last="Schenk">Maryjean Schenk</name>
<affiliation>
<nlm:affiliation>Department of Family Medicine and Public Health Sciences, Wayne State University, Detroit, MI 48201, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="De Roos, Anneclaire J" sort="De Roos, Anneclaire J" uniqKey="De Roos A" first="Anneclaire J" last="De Roos">Anneclaire J. De Roos</name>
<affiliation>
<nlm:affiliation>Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98117, USA; Department of Environmental and Occupational Health, Drexel University School of Public Health, Philadelphia, PA 19104, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Cozen, Wendy" sort="Cozen, Wendy" uniqKey="Cozen W" first="Wendy" last="Cozen">Wendy Cozen</name>
<affiliation>
<nlm:affiliation>Department of Preventive Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Norris Comprehensive Cancer Center, USC Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zhi, Degui" sort="Zhi, Degui" uniqKey="Zhi D" first="Degui" last="Zhi">Degui Zhi</name>
<affiliation>
<nlm:affiliation>Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35233, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Akers, Nicholas K" sort="Akers, Nicholas K" uniqKey="Akers N" first="Nicholas K" last="Akers">Nicholas K. Akers</name>
<affiliation>
<nlm:affiliation>Division of Environmental Health Sciences, University of California Berkeley School of Public Health, Berkeley, CA 94720, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Riby, Jacques" sort="Riby, Jacques" uniqKey="Riby J" first="Jacques" last="Riby">Jacques Riby</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center, Birmingham, AL 35233, USA; Division of Environmental Health Sciences, University of California Berkeley School of Public Health, Berkeley, CA 94720, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Smith, Martyn T" sort="Smith, Martyn T" uniqKey="Smith M" first="Martyn T" last="Smith">Martyn T. Smith</name>
<affiliation>
<nlm:affiliation>Division of Environmental Health Sciences, University of California Berkeley School of Public Health, Berkeley, CA 94720, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lacher, Mortimer" sort="Lacher, Mortimer" uniqKey="Lacher M" first="Mortimer" last="Lacher">Mortimer Lacher</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Villano, Danylo J" sort="Villano, Danylo J" uniqKey="Villano D" first="Danylo J" last="Villano">Danylo J. Villano</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Maria, Ann" sort="Maria, Ann" uniqKey="Maria A" first="Ann" last="Maria">Ann Maria</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Roman, Eve" sort="Roman, Eve" uniqKey="Roman E" first="Eve" last="Roman">Eve Roman</name>
<affiliation>
<nlm:affiliation>Department of Health Sciences, University of York, York YO10 5DD, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kane, Eleanor" sort="Kane, Eleanor" uniqKey="Kane E" first="Eleanor" last="Kane">Eleanor Kane</name>
<affiliation>
<nlm:affiliation>Department of Health Sciences, University of York, York YO10 5DD, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Jackson, Rebecca D" sort="Jackson, Rebecca D" uniqKey="Jackson R" first="Rebecca D" last="Jackson">Rebecca D. Jackson</name>
<affiliation>
<nlm:affiliation>Division of Endocrinology, Diabetes and Metabolism, The Ohio State University, Columbus, OH 43210, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E" last="North">Kari E. North</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Diver, W Ryan" sort="Diver, W Ryan" uniqKey="Diver W" first="W Ryan" last="Diver">W Ryan Diver</name>
<affiliation>
<nlm:affiliation>Epidemiology Research Program, American Cancer Society, Atlanta, GA 30303, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Turner, Jenny" sort="Turner, Jenny" uniqKey="Turner J" first="Jenny" last="Turner">Jenny Turner</name>
<affiliation>
<nlm:affiliation>Department of Anatomical Pathology, Australian School of Advanced Medicine, Macquarie University, Sydney, NSW 2109, Australia; Department of Histopathology, Douglass Hanly Moir Pathology, Macquarie Park, NSW 2113, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Armstrong, Bruce K" sort="Armstrong, Bruce K" uniqKey="Armstrong B" first="Bruce K" last="Armstrong">Bruce K. Armstrong</name>
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<nlm:affiliation>Sydney School of Public Health, The University of Sydney, Sydney, NSW 2006, Australia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Benavente, Yolanda" sort="Benavente, Yolanda" uniqKey="Benavente Y" first="Yolanda" last="Benavente">Yolanda Benavente</name>
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<nlm:affiliation>Unit of Infections and Cancer (UNIC), Cancer Epidemiology Research Programme, Institut Catala d'Oncologia, IDIBELL, Barcelona 8907, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Barcelona 8036, Spain.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Boffetta, Paolo" sort="Boffetta, Paolo" uniqKey="Boffetta P" first="Paolo" last="Boffetta">Paolo Boffetta</name>
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<nlm:affiliation>The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name>
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<nlm:affiliation>Group of Genetic Epidemiology, Section of Genetics, International Agency for Research on Cancer, Lyon 69372, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Foretova, Lenka" sort="Foretova, Lenka" uniqKey="Foretova L" first="Lenka" last="Foretova">Lenka Foretova</name>
<affiliation>
<nlm:affiliation>Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute and MF MU, Brno 656 53, Czech Republic.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Maynadie, Marc" sort="Maynadie, Marc" uniqKey="Maynadie M" first="Marc" last="Maynadie">Marc Maynadie</name>
<affiliation>
<nlm:affiliation>EA 4184, Registre des Hémopathies Malignes de Côte d'Or, University of Burgundy and Dijon University Hospital, Dijon 21070, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Staines, Anthony" sort="Staines, Anthony" uniqKey="Staines A" first="Anthony" last="Staines">Anthony Staines</name>
<affiliation>
<nlm:affiliation>School of Nursing and Human Sciences, Dublin City University, Dublin 9, Ireland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mckay, James" sort="Mckay, James" uniqKey="Mckay J" first="James" last="Mckay">James Mckay</name>
<affiliation>
<nlm:affiliation>Genetic Cancer Susceptibility Group, Section of Genetics, International Agency for Research on Cancer, Lyon 69372, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Brooks Wilson, Angela R" sort="Brooks Wilson, Angela R" uniqKey="Brooks Wilson A" first="Angela R" last="Brooks-Wilson">Angela R. Brooks-Wilson</name>
<affiliation>
<nlm:affiliation>Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 1L3, Canada; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Zheng, Tongzhang" sort="Zheng, Tongzhang" uniqKey="Zheng T" first="Tongzhang" last="Zheng">Tongzhang Zheng</name>
<affiliation>
<nlm:affiliation>Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT 06520, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Holford, Theodore R" sort="Holford, Theodore R" uniqKey="Holford T" first="Theodore R" last="Holford">Theodore R. Holford</name>
<affiliation>
<nlm:affiliation>Department of Biostatistics, Yale School of Public Health, New Haven, CT 06520, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chamosa, Saioa" sort="Chamosa, Saioa" uniqKey="Chamosa S" first="Saioa" last="Chamosa">Saioa Chamosa</name>
<affiliation>
<nlm:affiliation>Health Department, BioDonostia Research Institute, Basque Region 20014, Spain.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kaaks, Rudolph" sort="Kaaks, Rudolph" uniqKey="Kaaks R" first="Rudolph" last="Kaaks">Rudolph Kaaks</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Baden-Württemberg 69120, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kelly, Rachel S" sort="Kelly, Rachel S" uniqKey="Kelly R" first="Rachel S" last="Kelly">Rachel S. Kelly</name>
<affiliation>
<nlm:affiliation>MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ohlsson, Bodil" sort="Ohlsson, Bodil" uniqKey="Ohlsson B" first="Bodil" last="Ohlsson">Bodil Ohlsson</name>
<affiliation>
<nlm:affiliation>Department of Clinical Sciences, Division of Internal Medicine, Skåne University Hospital, Lund University, Malmö 205 02, Sweden.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C" last="Travis">Ruth C. Travis</name>
<affiliation>
<nlm:affiliation>Cancer Epidemiology Unit, University of Oxford, Oxford OX3 7LF, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
<affiliation>
<nlm:affiliation>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Breivika 9037, Norway; Cancer Registry of Norway, Oslo 0304, Norway; Department of Genetic Epidemiology, Folkhalsan Research Center, Helsinki 00250, Finland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Clavel, Jacqueline" sort="Clavel, Jacqueline" uniqKey="Clavel J" first="Jacqueline" last="Clavel">Jacqueline Clavel</name>
<affiliation>
<nlm:affiliation>Environmental Epidemiology of Cancer Group, Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Villejuif Cedex 94807, France; UMRS 1018, Université Paris Sud, Villejuif Cedex 94807, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Giovannucci, Edward" sort="Giovannucci, Edward" uniqKey="Giovannucci E" first="Edward" last="Giovannucci">Edward Giovannucci</name>
<affiliation>
<nlm:affiliation>Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA; Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA; Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name>
<affiliation>
<nlm:affiliation>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki 00271, Finland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Mazza, Patrizio" sort="Mazza, Patrizio" uniqKey="Mazza P" first="Patrizio" last="Mazza">Patrizio Mazza</name>
<affiliation>
<nlm:affiliation>Department of Hematology, Ospedale Nord, Taranto 74100, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Cocco, Pierluigi" sort="Cocco, Pierluigi" uniqKey="Cocco P" first="Pierluigi" last="Cocco">Pierluigi Cocco</name>
<affiliation>
<nlm:affiliation>Department of Public Health, Clinical and Molecular Medicine, University of Cagliari, Monserrato, Cagliari 09042, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ennas, Maria Grazia" sort="Ennas, Maria Grazia" uniqKey="Ennas M" first="Maria Grazia" last="Ennas">Maria Grazia Ennas</name>
<affiliation>
<nlm:affiliation>Department of Biomedical Science, University of Cagliari, Monserrato, Cagliari 09042, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chiu, Brian C H" sort="Chiu, Brian C H" uniqKey="Chiu B" first="Brian C H" last="Chiu">Brian C H. Chiu</name>
<affiliation>
<nlm:affiliation>Department of Health Studies, University of Chicago, Chicago, IL 60637, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Fraumeni, Joseph F" sort="Fraumeni, Joseph F" uniqKey="Fraumeni J" first="Joseph F" last="Fraumeni">Joseph F. Fraumeni</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Nieters, Alexandra" sort="Nieters, Alexandra" uniqKey="Nieters A" first="Alexandra" last="Nieters">Alexandra Nieters</name>
<affiliation>
<nlm:affiliation>Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Baden-Württemberg 79108, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name>
<affiliation>
<nlm:affiliation>Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wu, Xifeng" sort="Wu, Xifeng" uniqKey="Wu X" first="Xifeng" last="Wu">Xifeng Wu</name>
<affiliation>
<nlm:affiliation>Department of Epidemiology, M.D. Anderson Cancer Center, Houston, TX 77030, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Cerhan, James R" sort="Cerhan, James R" uniqKey="Cerhan J" first="James R" last="Cerhan">James R. Cerhan</name>
<affiliation>
<nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Smedby, Karin E" sort="Smedby, Karin E" uniqKey="Smedby K" first="Karin E" last="Smedby">Karin E. Smedby</name>
<affiliation>
<nlm:affiliation>Department of Medicine Solna, Karolinska Institutet, Stockholm 17176, Sweden.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Rothman, Nathaniel" sort="Rothman, Nathaniel" uniqKey="Rothman N" first="Nathaniel" last="Rothman">Nathaniel Rothman</name>
<affiliation>
<nlm:affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series>
<title level="j">American journal of human genetics</title>
<idno type="eISSN">1537-6605</idno>
<imprint>
<date when="2014" type="published">2014</date>
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<term>Alleles</term>
<term>Biomarkers, Tumor (genetics)</term>
<term>Case-Control Studies</term>
<term>Chromosomes, Human (genetics)</term>
<term>Genetic Predisposition to Disease</term>
<term>Genome-Wide Association Study</term>
<term>HLA Antigens (genetics)</term>
<term>Haplotypes (genetics)</term>
<term>Humans</term>
<term>Lymphoma, Follicular (genetics)</term>
<term>Polymorphism, Single Nucleotide (genetics)</term>
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<term>Biomarkers, Tumor</term>
<term>HLA Antigens</term>
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<term>Chromosomes, Human</term>
<term>Haplotypes</term>
<term>Lymphoma, Follicular</term>
<term>Polymorphism, Single Nucleotide</term>
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<term>Alleles</term>
<term>Case-Control Studies</term>
<term>Genetic Predisposition to Disease</term>
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<front>
<div type="abstract" xml:lang="en">Genome-wide association studies (GWASs) of follicular lymphoma (FL) have previously identified human leukocyte antigen (HLA) gene variants. To identify additional FL susceptibility loci, we conducted a large-scale two-stage GWAS in 4,523 case subjects and 13,344 control subjects of European ancestry. Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. In an analysis of the HLA region, we identified four linked HLA-DRβ1 multiallelic amino acids at positions 11, 13, 28, and 30 that were associated with FL risk (pomnibus = 4.20 × 10(-67) to 2.67 × 10(-70)). Additional independent signals included rs17203612 in HLA class II (odds ratio [OR(per-allele)] = 1.44; p = 4.59 × 10(-16)) and rs3130437 in HLA class I (OR(per-allele) = 1.23; p = 8.23 × 10(-9)). Our findings further expand the number of loci associated with FL and provide evidence that multiple common variants outside the HLA region make a significant contribution to FL risk.</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">25279986</PMID>
<DateCreated>
<Year>2014</Year>
<Month>10</Month>
<Day>04</Day>
</DateCreated>
<DateCompleted>
<Year>2014</Year>
<Month>12</Month>
<Day>09</Day>
</DateCompleted>
<DateRevised>
<Year>2017</Year>
<Month>08</Month>
<Day>30</Day>
</DateRevised>
<Article PubModel="Print">
<Journal>
<ISSN IssnType="Electronic">1537-6605</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>95</Volume>
<Issue>4</Issue>
<PubDate>
<Year>2014</Year>
<Month>Oct</Month>
<Day>02</Day>
</PubDate>
</JournalIssue>
<Title>American journal of human genetics</Title>
<ISOAbbreviation>Am. J. Hum. Genet.</ISOAbbreviation>
</Journal>
<ArticleTitle>Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.</ArticleTitle>
<Pagination>
<MedlinePgn>462-71</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ajhg.2014.09.004</ELocationID>
<ELocationID EIdType="pii" ValidYN="Y">S0002-9297(14)00387-5</ELocationID>
<Abstract>
<AbstractText>Genome-wide association studies (GWASs) of follicular lymphoma (FL) have previously identified human leukocyte antigen (HLA) gene variants. To identify additional FL susceptibility loci, we conducted a large-scale two-stage GWAS in 4,523 case subjects and 13,344 control subjects of European ancestry. Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10(-10)) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10(-8)) near PVT1. In an analysis of the HLA region, we identified four linked HLA-DRβ1 multiallelic amino acids at positions 11, 13, 28, and 30 that were associated with FL risk (pomnibus = 4.20 × 10(-67) to 2.67 × 10(-70)). Additional independent signals included rs17203612 in HLA class II (odds ratio [OR(per-allele)] = 1.44; p = 4.59 × 10(-16)) and rs3130437 in HLA class I (OR(per-allele) = 1.23; p = 8.23 × 10(-9)). Our findings further expand the number of loci associated with FL and provide evidence that multiple common variants outside the HLA region make a significant contribution to FL risk.</AbstractText>
<CopyrightInformation>Copyright © 2014 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Skibola</LastName>
<ForeName>Christine F</ForeName>
<Initials>CF</Initials>
<AffiliationInfo>
<Affiliation>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center, Birmingham, AL 35233, USA; Division of Environmental Health Sciences, University of California Berkeley School of Public Health, Berkeley, CA 94720, USA. Electronic address: cskibola@uab.edu.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Berndt</LastName>
<ForeName>Sonja I</ForeName>
<Initials>SI</Initials>
<AffiliationInfo>
<Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Vijai</LastName>
<ForeName>Joseph</ForeName>
<Initials>J</Initials>
<AffiliationInfo>
<Affiliation>Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Conde</LastName>
<ForeName>Lucia</ForeName>
<Initials>L</Initials>
<AffiliationInfo>
<Affiliation>Department of Epidemiology, School of Public Health and Comprehensive Cancer Center, Birmingham, AL 35233, USA; Division of Environmental Health Sciences, University of California Berkeley School of Public Health, Berkeley, CA 94720, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Wang</LastName>
<ForeName>Zhaoming</ForeName>
<Initials>Z</Initials>
<AffiliationInfo>
<Affiliation>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Gaithersburg, MD 20877, USA.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Yeager</LastName>
<ForeName>Meredith</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Gaithersburg, MD 20877, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>de Bakker</LastName>
<ForeName>Paul I W</ForeName>
<Initials>PI</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Genetics and of Epidemiology, University Medical Center Utrecht, Utrecht 3584 CG, the Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht 3584 CX, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Birmann</LastName>
<ForeName>Brenda M</ForeName>
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<AffiliationInfo>
<Affiliation>Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.</Affiliation>
</AffiliationInfo>
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<LastName>Vajdic</LastName>
<ForeName>Claire M</ForeName>
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<Affiliation>Prince of Wales Clinical School, University of New South Wales, Sydney, NSW 2052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Foo</LastName>
<ForeName>Jia-Nee</ForeName>
<Initials>JN</Initials>
<AffiliationInfo>
<Affiliation>Human Genetics, Genome Institute of Singapore, Singapore 138672, Singapore.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Bracci</LastName>
<ForeName>Paige M</ForeName>
<Initials>PM</Initials>
<AffiliationInfo>
<Affiliation>Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA 94118, USA.</Affiliation>
</AffiliationInfo>
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<LastName>Vermeulen</LastName>
<ForeName>Roel C H</ForeName>
<Initials>RC</Initials>
<AffiliationInfo>
<Affiliation>Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht 3584 CX, the Netherlands; Institute for Risk Assessment Sciences, Utrecht University, Utrecht 3508 TD, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Slager</LastName>
<ForeName>Susan L</ForeName>
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<AffiliationInfo>
<Affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>de Sanjose</LastName>
<ForeName>Silvia</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Unit of Infections and Cancer (UNIC), Cancer Epidemiology Research Programme, Institut Catala d'Oncologia, IDIBELL, Barcelona 8907, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Barcelona 8036, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Wang</LastName>
<ForeName>Sophia S</ForeName>
<Initials>SS</Initials>
<AffiliationInfo>
<Affiliation>Department of Cancer Etiology, City of Hope Beckman Research Institute, Duarte, CA 91030, USA.</Affiliation>
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</Author>
<Author ValidYN="Y">
<LastName>Linet</LastName>
<ForeName>Martha S</ForeName>
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<Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</Affiliation>
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</Author>
<Author ValidYN="Y">
<LastName>Salles</LastName>
<ForeName>Gilles</ForeName>
<Initials>G</Initials>
<AffiliationInfo>
<Affiliation>Department of Hematology, Hospices Civils de Lyon, Pierre benite Cedex 69495, France; Department of Hematology, Université Lyon-1, Pierre benite Cedex 69495, France; Laboratoire de Biologie Moléculaire de la Cellule UMR 5239, Centre National de la Recherche Scientifique, Pierre benite Cedex 69495, France.</Affiliation>
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<LastName>Lan</LastName>
<ForeName>Qing</ForeName>
<Initials>Q</Initials>
<AffiliationInfo>
<Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</Affiliation>
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<LastName>Severi</LastName>
<ForeName>Gianluca</ForeName>
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<AffiliationInfo>
<Affiliation>Human Genetics Foundation, Turin 10126, Italy; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC 3053, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Carlton, VIC 3010, Australia.</Affiliation>
</AffiliationInfo>
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<LastName>Hjalgrim</LastName>
<ForeName>Henrik</ForeName>
<Initials>H</Initials>
<AffiliationInfo>
<Affiliation>Department of Epidemiology Research, Division of Health Surveillance and Research, Statens Serum Institut, Copenhagen 2300, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Lightfoot</LastName>
<ForeName>Tracy</ForeName>
<Initials>T</Initials>
<AffiliationInfo>
<Affiliation>Department of Health Sciences, University of York, York YO10 5DD, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Melbye</LastName>
<ForeName>Mads</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Epidemiology Research, Division of Health Surveillance and Research, Statens Serum Institut, Copenhagen 2300, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.</Affiliation>
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<LastName>Gu</LastName>
<ForeName>Jian</ForeName>
<Initials>J</Initials>
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<Affiliation>Department of Epidemiology, M.D. Anderson Cancer Center, Houston, TX 77030, USA.</Affiliation>
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<LastName>Ghesquières</LastName>
<ForeName>Hervé</ForeName>
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<Affiliation>Laboratoire de Biologie Moléculaire de la Cellule UMR 5239, Centre National de la Recherche Scientifique, Pierre benite Cedex 69495, France; Department of Hematology, Centre Léon Bérard, Lyon 69008, France.</Affiliation>
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<LastName>Link</LastName>
<ForeName>Brian K</ForeName>
<Initials>BK</Initials>
<AffiliationInfo>
<Affiliation>Department of Internal Medicine, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA.</Affiliation>
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<LastName>Morton</LastName>
<ForeName>Lindsay M</ForeName>
<Initials>LM</Initials>
<AffiliationInfo>
<Affiliation>Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.</Affiliation>
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<LastName>Holly</LastName>
<ForeName>Elizabeth A</ForeName>
<Initials>EA</Initials>
<AffiliationInfo>
<Affiliation>Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA 94118, USA.</Affiliation>
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</Author>
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<LastName>Smith</LastName>
<ForeName>Alex</ForeName>
<Initials>A</Initials>
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<Affiliation>Department of Health Sciences, University of York, York YO10 5DD, UK.</Affiliation>
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