Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.
Identifieur interne : 003196 ( PubMed/Corpus ); précédent : 003195; suivant : 003197Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.
Auteurs : Paolo Peterlongo ; Jenny Chang-Claude ; Kirsten B. Moysich ; Anja Rudolph ; Rita K. Schmutzler ; Jacques Simard ; Penny Soucy ; Rosalind A. Eeles ; Douglas F. Easton ; Ute Hamann ; Stefan Wilkening ; Bowang Chen ; Matti A. Rookus ; Marjanka K. Schmidt ; Frederieke H. Van Der Baan ; Amanda B. Spurdle ; Logan C. Walker ; Felicity Lose ; Ana-Teresa Maia ; Marco Montagna ; Laura Matricardi ; Jan Lubinski ; Anna Jakubowska ; Encarna B. G Mez Garcia ; Olufunmilayo I. Olopade ; Robert L. Nussbaum ; Katherine L. Nathanson ; Susan M. Domchek ; Timothy R. Rebbeck ; Banu K. Arun ; Beth Y. Karlan ; Sandra Orsulic ; Jenny Lester ; Wendy K. Chung ; Alex Miron ; Melissa C. Southey ; David E. Goldgar ; Saundra S. Buys ; Ramunas Janavicius ; Cecilia M. Dorfling ; Elizabeth J. Van Rensburg ; Yuan Chun Ding ; Susan L. Neuhausen ; Thomas V O. Hansen ; Anne-Marie Gerdes ; Bent Ejlertsen ; Lars J Nson ; Ana Osorio ; Cristina Martínez-Bouzas ; Javier Benitez ; Edye E. Conway ; Kathleen R. Blazer ; Jeffrey N. Weitzel ; Siranoush Manoukian ; Bernard Peissel ; Daniela Zaffaroni ; Giulietta Scuvera ; Monica Barile ; Filomena Ficarazzi ; Frederique Mariette ; Stefano Fortuzzi ; Alessandra Viel ; Giuseppe Giannini ; Laura Papi ; Aline Martayan ; Maria Grazia Tibiletti ; Paolo Radice ; Athanassios Vratimos ; Florentia Fostira ; Judy E. Garber ; Alan Donaldson ; Carole Brewer ; Claire Foo ; D Gareth R. Evans ; Debra Frost ; Diana Eccles ; Angela Brady ; Jackie Cook ; Marc Tischkowitz ; Julian Adlard ; Julian Barwell ; Lisa Walker ; Louise Izatt ; Lucy E. Side ; M John Kennedy ; Mark T. Rogers ; Mary E. Porteous ; Patrick J. Morrison ; Radka Platte ; Rosemarie Davidson ; Shirley V. Hodgson ; Steve Ellis ; Trevor Cole ; Andrew K. Godwin ; Kathleen Claes ; Tom Van Maerken ; Alfons Meindl ; Andrea Gehrig ; Christian Sutter ; Christoph Engel ; Dieter Niederacher ; Doris Steinemann ; Hansjoerg Plendl ; Karin Kast ; Kerstin Rhiem ; Nina Ditsch ; Norbert Arnold ; Raymonda Varon-Mateeva ; Barbara Wappenschmidt ; Shan Wang-Gohrke ; Brigitte Bressac-De Paillerets ; Bruno Buecher ; Capucine Delnatte ; Claude Houdayer ; Dominique Stoppa-Lyonnet ; Francesca Damiola ; Isabelle Coupier ; Laure Barjhoux ; Laurence Venat-Bouvet ; Lisa Golmard ; Nadia Boutry-Kryza ; Olga M. Sinilnikova ; Olivier Caron ; Pascal Pujol ; Sylvie Mazoyer ; Muriel Belotti ; Marion Piedmonte ; Michael L. Friedlander ; Gustavo C. Rodriguez ; Larry J. Copeland ; Miguel De La Hoya ; Pedro Perez Segura ; Heli Nevanlinna ; Kristiina Aittom Ki ; Theo A M. Van Os ; Hanne E J. Meijers-Heijboer ; Annemarie H. Van Der Hout ; Maaike P G. Vreeswijk ; Nicoline Hoogerbrugge ; Margreet G E M. Ausems ; Helena C. Van Doorn ; J Margriet Collée ; Edith Olah ; Orland Diez ; Ignacio Blanco ; Conxi Lazaro ; Joan Brunet ; Lidia Feliubadalo ; Cezary Cybulski ; Jacek Gronwald ; Katarzyna Durda ; Katarzyna Jaworska-Bieniek ; Grzegorz Sukiennicki ; Adalgeir Arason ; Jocelyne Chiquette ; Manuel R. Teixeira ; Curtis Olswold ; Fergus J. Couch ; Noralane M. Lindor ; Xianshu Wang ; Csilla I. Szabo ; Kenneth Offit ; Marina Corines ; Lauren Jacobs ; Mark E. Robson ; Liying Zhang ; Vijai Joseph ; Andreas Berger ; Christian F. Singer ; Christine Rappaport ; Daphne Geschwantler Kaulich ; Georg Pfeiler ; Muy-Kheng M. Tea ; Catherine M. Phelan ; Mark H. Greene ; Phuong L. Mai ; Gad Rennert ; Anna Marie Mulligan ; Gord Glendon ; Sandrine Tchatchou ; Irene L. Andrulis ; Amanda Ewart Toland ; Anders Bojesen ; Inge Sokilde Pedersen ; Mads Thomassen ; Uffe Birk Jensen ; Yael Laitman ; Johanna Rantala ; Anna Von Wachenfeldt ; Hans Ehrencrona ; Marie Stenmark Askmalm ; Ke Borg ; Karoline B. Kuchenbaecker ; Lesley Mcguffog ; Daniel Barrowdale ; Sue Healey ; Andrew Lee ; Paul D P. Pharoah ; Georgia Chenevix-Trench ; Antonis C. Antoniou ; Eitan FriedmanSource :
- Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology [ 1538-7755 ] ; 2015.
English descriptors
- KwdEn :
- MESH :
- genetics : Breast Neoplasms, Ovarian Neoplasms.
- physiology : Genes, BRCA1, Genes, BRCA2.
- Adult, Cohort Studies, Female, Humans, Mutation, Polymorphism, Single Nucleotide, Retrospective Studies, Young Adult.
Abstract
BRCA1 and BRCA2 mutation carriers are at substantially increased risk for developing breast and ovarian cancer. The incomplete penetrance coupled with the variable age at diagnosis in carriers of the same mutation suggests the existence of genetic and nongenetic modifying factors. In this study, we evaluated the putative role of variants in many candidate modifier genes.
DOI: 10.1158/1055-9965.EPI-14-0532
PubMed: 25336561
Links to Exploration step
pubmed:25336561Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.</title><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation><nlm:affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy. paolo.peterlongo@ifom.eu eitan.friedman@sheba.health.gov.il feitan@post.tau.ac.il.</nlm:affiliation></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Moysich, Kirsten B" sort="Moysich, Kirsten B" uniqKey="Moysich K" first="Kirsten B" last="Moysich">Kirsten B. Moysich</name><affiliation><nlm:affiliation>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K" last="Schmutzler">Rita K. Schmutzler</name><affiliation><nlm:affiliation>Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne, Germany. Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Germany. Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany, on behalf of the German Consortium of Hereditary Breast and Ovarian Cancer (GC-HBOC).</nlm:affiliation></affiliation></author><author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name><affiliation><nlm:affiliation>Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Soucy, Penny" sort="Soucy, Penny" uniqKey="Soucy P" first="Penny" last="Soucy">Penny Soucy</name><affiliation><nlm:affiliation>Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Eeles, Rosalind A" sort="Eeles, Rosalind A" uniqKey="Eeles R" first="Rosalind A" last="Eeles">Rosalind A. Eeles</name><affiliation><nlm:affiliation>Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Surrey, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wilkening, Stefan" sort="Wilkening, Stefan" uniqKey="Wilkening S" first="Stefan" last="Wilkening">Stefan Wilkening</name><affiliation><nlm:affiliation>Genomic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, Bowang" sort="Chen, Bowang" uniqKey="Chen B" first="Bowang" last="Chen">Bowang Chen</name><affiliation><nlm:affiliation>Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Rookus, Matti A" sort="Rookus, Matti A" uniqKey="Rookus M" first="Matti A" last="Rookus">Matti A. Rookus</name><affiliation><nlm:affiliation>Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K" last="Schmidt">Marjanka K. Schmidt</name><affiliation><nlm:affiliation>Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Van Der Baan, Frederieke H" sort="Van Der Baan, Frederieke H" uniqKey="Van Der Baan F" first="Frederieke H" last="Van Der Baan">Frederieke H. Van Der Baan</name><affiliation><nlm:affiliation>Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B" last="Spurdle">Amanda B. Spurdle</name><affiliation><nlm:affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Walker, Logan C" sort="Walker, Logan C" uniqKey="Walker L" first="Logan C" last="Walker">Logan C. Walker</name><affiliation><nlm:affiliation>Department of Pathology, University of Otago, Christchurch, New Zealand.</nlm:affiliation></affiliation></author><author><name sortKey="Lose, Felicity" sort="Lose, Felicity" uniqKey="Lose F" first="Felicity" last="Lose">Felicity Lose</name><affiliation><nlm:affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Maia, Ana Teresa" sort="Maia, Ana Teresa" uniqKey="Maia A" first="Ana-Teresa" last="Maia">Ana-Teresa Maia</name><affiliation><nlm:affiliation>Department of Biomedical Sciences and Medicine, Gambelas Campus, University of Algarve, Portugal.</nlm:affiliation></affiliation></author><author><name sortKey="Montagna, Marco" sort="Montagna, Marco" uniqKey="Montagna M" first="Marco" last="Montagna">Marco Montagna</name><affiliation><nlm:affiliation>Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV - IRCCS, Padua, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Matricardi, Laura" sort="Matricardi, Laura" uniqKey="Matricardi L" first="Laura" last="Matricardi">Laura Matricardi</name><affiliation><nlm:affiliation>Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV - IRCCS, Padua, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="G Mez Garcia, Encarna B" sort="G Mez Garcia, Encarna B" uniqKey="G Mez Garcia E" first="Encarna B" last="G Mez Garcia">Encarna B. G Mez Garcia</name><affiliation><nlm:affiliation>Department of Clinical Genetics, MUMC, Maastricht, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Olopade, Olufunmilayo I" sort="Olopade, Olufunmilayo I" uniqKey="Olopade O" first="Olufunmilayo I" last="Olopade">Olufunmilayo I. Olopade</name><affiliation><nlm:affiliation>Center for Clinical Cancer Genetics, Department of Medicine and Human Genetics, University of Chicago Medical Center, Chicago, Illinois.</nlm:affiliation></affiliation></author><author><name sortKey="Nussbaum, Robert L" sort="Nussbaum, Robert L" uniqKey="Nussbaum R" first="Robert L" last="Nussbaum">Robert L. Nussbaum</name><affiliation><nlm:affiliation>Department of Medicine and Institute for Human Genetics, University of California, San Francisco, San Francisco, California.</nlm:affiliation></affiliation></author><author><name sortKey="Nathanson, Katherine L" sort="Nathanson, Katherine L" uniqKey="Nathanson K" first="Katherine L" last="Nathanson">Katherine L. Nathanson</name><affiliation><nlm:affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadephia, Pennsylvania.</nlm:affiliation></affiliation></author><author><name sortKey="Domchek, Susan M" sort="Domchek, Susan M" uniqKey="Domchek S" first="Susan M" last="Domchek">Susan M. Domchek</name><affiliation><nlm:affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadephia, Pennsylvania.</nlm:affiliation></affiliation></author><author><name sortKey="Rebbeck, Timothy R" sort="Rebbeck, Timothy R" uniqKey="Rebbeck T" first="Timothy R" last="Rebbeck">Timothy R. Rebbeck</name><affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadephia, Pennsylvania.</nlm:affiliation></affiliation></author><author><name sortKey="Arun, Banu K" sort="Arun, Banu K" uniqKey="Arun B" first="Banu K" last="Arun">Banu K. Arun</name><affiliation><nlm:affiliation>University of Texas MD Anderson Cancer Center, Houston, Texas.</nlm:affiliation></affiliation></author><author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y" last="Karlan">Beth Y. Karlan</name><affiliation><nlm:affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.</nlm:affiliation></affiliation></author><author><name sortKey="Orsulic, Sandra" sort="Orsulic, Sandra" uniqKey="Orsulic S" first="Sandra" last="Orsulic">Sandra Orsulic</name><affiliation><nlm:affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.</nlm:affiliation></affiliation></author><author><name sortKey="Lester, Jenny" sort="Lester, Jenny" uniqKey="Lester J" first="Jenny" last="Lester">Jenny Lester</name><affiliation><nlm:affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.</nlm:affiliation></affiliation></author><author><name sortKey="Chung, Wendy K" sort="Chung, Wendy K" uniqKey="Chung W" first="Wendy K" last="Chung">Wendy K. Chung</name><affiliation><nlm:affiliation>Departments of Pediatrics and Medicine, Columbia University, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Miron, Alex" sort="Miron, Alex" uniqKey="Miron A" first="Alex" last="Miron">Alex Miron</name><affiliation><nlm:affiliation>Department of Genetics and Genomics at Case Western Reserve Medical School, Cleveland, Ohio.</nlm:affiliation></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C" last="Southey">Melissa C. Southey</name><affiliation><nlm:affiliation>Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Goldgar, David E" sort="Goldgar, David E" uniqKey="Goldgar D" first="David E" last="Goldgar">David E. Goldgar</name><affiliation><nlm:affiliation>Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah.</nlm:affiliation></affiliation></author><author><name sortKey="Buys, Saundra S" sort="Buys, Saundra S" uniqKey="Buys S" first="Saundra S" last="Buys">Saundra S. Buys</name><affiliation><nlm:affiliation>Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah.</nlm:affiliation></affiliation></author><author><name sortKey="Janavicius, Ramunas" sort="Janavicius, Ramunas" uniqKey="Janavicius R" first="Ramunas" last="Janavicius">Ramunas Janavicius</name><affiliation><nlm:affiliation>Vilnius University Hospital Santariskiu Clinics, Hematology, Oncology, and Transfusion Medicine Center, Dept. of Molecular and Regenerative Medicine; State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania.</nlm:affiliation></affiliation></author><author><name sortKey="Dorfling, Cecilia M" sort="Dorfling, Cecilia M" uniqKey="Dorfling C" first="Cecilia M" last="Dorfling">Cecilia M. Dorfling</name><affiliation><nlm:affiliation>Department of Genetics, University of Pretoria, Pretoria, South Africa.</nlm:affiliation></affiliation></author><author><name sortKey="Van Rensburg, Elizabeth J" sort="Van Rensburg, Elizabeth J" uniqKey="Van Rensburg E" first="Elizabeth J" last="Van Rensburg">Elizabeth J. Van Rensburg</name><affiliation><nlm:affiliation>Department of Genetics, University of Pretoria, Pretoria, South Africa.</nlm:affiliation></affiliation></author><author><name sortKey="Ding, Yuan Chun" sort="Ding, Yuan Chun" uniqKey="Ding Y" first="Yuan Chun" last="Ding">Yuan Chun Ding</name><affiliation><nlm:affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California.</nlm:affiliation></affiliation></author><author><name sortKey="Neuhausen, Susan L" sort="Neuhausen, Susan L" uniqKey="Neuhausen S" first="Susan L" last="Neuhausen">Susan L. Neuhausen</name><affiliation><nlm:affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California.</nlm:affiliation></affiliation></author><author><name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V O" last="Hansen">Thomas V O. Hansen</name><affiliation><nlm:affiliation>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Gerdes, Anne Marie" sort="Gerdes, Anne Marie" uniqKey="Gerdes A" first="Anne-Marie" last="Gerdes">Anne-Marie Gerdes</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name><affiliation><nlm:affiliation>Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="J Nson, Lars" sort="J Nson, Lars" uniqKey="J Nson L" first="Lars" last="J Nson">Lars J Nson</name><affiliation><nlm:affiliation>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Osorio, Ana" sort="Osorio, Ana" uniqKey="Osorio A" first="Ana" last="Osorio">Ana Osorio</name><affiliation><nlm:affiliation>Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Martinez Bouzas, Cristina" sort="Martinez Bouzas, Cristina" uniqKey="Martinez Bouzas C" first="Cristina" last="Martínez-Bouzas">Cristina Martínez-Bouzas</name><affiliation><nlm:affiliation>Molecular Genetics Laboratory, Department of Biochemistry, Cruces Hospital Barakaldo, 48903-Barakaldo-Bizkaia, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><affiliation><nlm:affiliation>Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. Human Genetics Group and Genotyping Unit, Spanish National Cancer Centre (CNIO), Madrid, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Conway, Edye E" sort="Conway, Edye E" uniqKey="Conway E" first="Edye E" last="Conway">Edye E. Conway</name><affiliation><nlm:affiliation>Saint Alphonsus Regional Medical Center, care of City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California.</nlm:affiliation></affiliation></author><author><name sortKey="Blazer, Kathleen R" sort="Blazer, Kathleen R" uniqKey="Blazer K" first="Kathleen R" last="Blazer">Kathleen R. Blazer</name><affiliation><nlm:affiliation>Clinical Cancer Genetics, City of Hope, Duarte, California.</nlm:affiliation></affiliation></author><author><name sortKey="Weitzel, Jeffrey N" sort="Weitzel, Jeffrey N" uniqKey="Weitzel J" first="Jeffrey N" last="Weitzel">Jeffrey N. Weitzel</name><affiliation><nlm:affiliation>Clinical Cancer Genetics, City of Hope, Duarte, California (for the City of Hope Clinical Cancer Genetics Community Research Network).</nlm:affiliation></affiliation></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name><affiliation><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name><affiliation><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Zaffaroni, Daniela" sort="Zaffaroni, Daniela" uniqKey="Zaffaroni D" first="Daniela" last="Zaffaroni">Daniela Zaffaroni</name><affiliation><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Scuvera, Giulietta" sort="Scuvera, Giulietta" uniqKey="Scuvera G" first="Giulietta" last="Scuvera">Giulietta Scuvera</name><affiliation><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Barile, Monica" sort="Barile, Monica" uniqKey="Barile M" first="Monica" last="Barile">Monica Barile</name><affiliation><nlm:affiliation>Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Ficarazzi, Filomena" sort="Ficarazzi, Filomena" uniqKey="Ficarazzi F" first="Filomena" last="Ficarazzi">Filomena Ficarazzi</name><affiliation><nlm:affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Cogentech Cancer Genetic Test Laboratory, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Mariette, Frederique" sort="Mariette, Frederique" uniqKey="Mariette F" first="Frederique" last="Mariette">Frederique Mariette</name><affiliation><nlm:affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Cogentech Cancer Genetic Test Laboratory, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Fortuzzi, Stefano" sort="Fortuzzi, Stefano" uniqKey="Fortuzzi S" first="Stefano" last="Fortuzzi">Stefano Fortuzzi</name><affiliation><nlm:affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Cogentech Cancer Genetic Test Laboratory, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Viel, Alessandra" sort="Viel, Alessandra" uniqKey="Viel A" first="Alessandra" last="Viel">Alessandra Viel</name><affiliation><nlm:affiliation>Division of Experimental Oncology 1, CRO Aviano National Cancer Institute, Aviano (PN), Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Giannini, Giuseppe" sort="Giannini, Giuseppe" uniqKey="Giannini G" first="Giuseppe" last="Giannini">Giuseppe Giannini</name><affiliation><nlm:affiliation>Department of Molecular Medicine, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Papi, Laura" sort="Papi, Laura" uniqKey="Papi L" first="Laura" last="Papi">Laura Papi</name><affiliation><nlm:affiliation>Unit of Medical Genetics, Department of Biomedical, Experimental, and Clinical Sciences, University of Florence, Florence, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Martayan, Aline" sort="Martayan, Aline" uniqKey="Martayan A" first="Aline" last="Martayan">Aline Martayan</name><affiliation><nlm:affiliation>Unit of Genetic Counseling, Medical Oncology Department, Istituto Nazionale Tumori Regina Elena, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Tibiletti, Maria Grazia" sort="Tibiletti, Maria Grazia" uniqKey="Tibiletti M" first="Maria Grazia" last="Tibiletti">Maria Grazia Tibiletti</name><affiliation><nlm:affiliation>UO Anatomia Patologica Ospedale di Circolo e Fondazione Macchi, Polo Universitario Varese, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation><nlm:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Vratimos, Athanassios" sort="Vratimos, Athanassios" uniqKey="Vratimos A" first="Athanassios" last="Vratimos">Athanassios Vratimos</name><affiliation><nlm:affiliation>Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens, Greece.</nlm:affiliation></affiliation></author><author><name sortKey="Fostira, Florentia" sort="Fostira, Florentia" uniqKey="Fostira F" first="Florentia" last="Fostira">Florentia Fostira</name><affiliation><nlm:affiliation>Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens, Greece.</nlm:affiliation></affiliation></author><author><name sortKey="Garber, Judy E" sort="Garber, Judy E" uniqKey="Garber J" first="Judy E" last="Garber">Judy E. Garber</name><affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachuestts.</nlm:affiliation></affiliation></author><author><name sortKey="Donaldson, Alan" sort="Donaldson, Alan" uniqKey="Donaldson A" first="Alan" last="Donaldson">Alan Donaldson</name><affiliation><nlm:affiliation>Clinical Genetics Department, St. Michael's Hospital, Bristol, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Brewer, Carole" sort="Brewer, Carole" uniqKey="Brewer C" first="Carole" last="Brewer">Carole Brewer</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Royal Devon & Exeter Hospital, Exeter, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Foo, Claire" sort="Foo, Claire" uniqKey="Foo C" first="Claire" last="Foo">Claire Foo</name><affiliation><nlm:affiliation>Cheshire & Merseyside Clinical Genetics Service, Liverpool Women's NHS Foundation Trust, Liverpool, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Evans, D Gareth R" sort="Evans, D Gareth R" uniqKey="Evans D" first="D Gareth R" last="Evans">D Gareth R. Evans</name><affiliation><nlm:affiliation>Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Frost, Debra" sort="Frost, Debra" uniqKey="Frost D" first="Debra" last="Frost">Debra Frost</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name><affiliation><nlm:affiliation>University of Southampton, Faculty of Medicine, Southampton University Hospitals NHS Trust, Southampton, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Brady, Angela" sort="Brady, Angela" uniqKey="Brady A" first="Angela" last="Brady">Angela Brady</name><affiliation><nlm:affiliation>North West Thames Regional Genetics Service, Kennedy-Galton Centre, Harrow, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Cook, Jackie" sort="Cook, Jackie" uniqKey="Cook J" first="Jackie" last="Cook">Jackie Cook</name><affiliation><nlm:affiliation>Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Tischkowitz, Marc" sort="Tischkowitz, Marc" uniqKey="Tischkowitz M" first="Marc" last="Tischkowitz">Marc Tischkowitz</name><affiliation><nlm:affiliation>Department of Clinical Genetics, East Anglian Regional Genetics Service, Addenbrookes Hospital, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name><affiliation><nlm:affiliation>Yorkshire Regional Genetics Service, Leeds, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Barwell, Julian" sort="Barwell, Julian" uniqKey="Barwell J" first="Julian" last="Barwell">Julian Barwell</name><affiliation><nlm:affiliation>Leicestershire Clinical Genetics Service, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Walker, Lisa" sort="Walker, Lisa" uniqKey="Walker L" first="Lisa" last="Walker">Lisa Walker</name><affiliation><nlm:affiliation>Oxford Regional Genetics Service, Churchill Hospital, Oxford, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Izatt, Louise" sort="Izatt, Louise" uniqKey="Izatt L" first="Louise" last="Izatt">Louise Izatt</name><affiliation><nlm:affiliation>Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Side, Lucy E" sort="Side, Lucy E" uniqKey="Side L" first="Lucy E" last="Side">Lucy E. Side</name><affiliation><nlm:affiliation>North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Kennedy, M John" sort="Kennedy, M John" uniqKey="Kennedy M" first="M John" last="Kennedy">M John Kennedy</name><affiliation><nlm:affiliation>Academic Unit of Clinical and Molecular Oncology, Trinity College Dublin, Ireland. St. James's Hospital, Dublin, Ireland.</nlm:affiliation></affiliation></author><author><name sortKey="Rogers, Mark T" sort="Rogers, Mark T" uniqKey="Rogers M" first="Mark T" last="Rogers">Mark T. Rogers</name><affiliation><nlm:affiliation>All Wales Medical Genetics Services, University Hospital of Wales, Cardiff, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Porteous, Mary E" sort="Porteous, Mary E" uniqKey="Porteous M" first="Mary E" last="Porteous">Mary E. Porteous</name><affiliation><nlm:affiliation>South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Morrison, Patrick J" sort="Morrison, Patrick J" uniqKey="Morrison P" first="Patrick J" last="Morrison">Patrick J. Morrison</name><affiliation><nlm:affiliation>Centre for Cancer Research and Cell Biology, Queens University of Belfast, Department of Medical Genetics, Belfast HSC Trust, Belfast, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Platte, Radka" sort="Platte, Radka" uniqKey="Platte R" first="Radka" last="Platte">Radka Platte</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Davidson, Rosemarie" sort="Davidson, Rosemarie" uniqKey="Davidson R" first="Rosemarie" last="Davidson">Rosemarie Davidson</name><affiliation><nlm:affiliation>West of Scotland Regional Genetics Service, Southern General Hospital, Glasgow, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Hodgson, Shirley V" sort="Hodgson, Shirley V" uniqKey="Hodgson S" first="Shirley V" last="Hodgson">Shirley V. Hodgson</name><affiliation><nlm:affiliation>Medical Genetics Unit, St. George's, University of London, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Ellis, Steve" sort="Ellis, Steve" uniqKey="Ellis S" first="Steve" last="Ellis">Steve Ellis</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Cole, Trevor" sort="Cole, Trevor" uniqKey="Cole T" first="Trevor" last="Cole">Trevor Cole</name><affiliation><nlm:affiliation>West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K" last="Godwin">Andrew K. Godwin</name><affiliation><nlm:affiliation>Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Missouri.</nlm:affiliation></affiliation></author><author><name sortKey="Claes, Kathleen" sort="Claes, Kathleen" uniqKey="Claes K" first="Kathleen" last="Claes">Kathleen Claes</name><affiliation><nlm:affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Van Maerken, Tom" sort="Van Maerken, Tom" uniqKey="Van Maerken T" first="Tom" last="Van Maerken">Tom Van Maerken</name><affiliation><nlm:affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation><nlm:affiliation>Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University Munich, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Gehrig, Andrea" sort="Gehrig, Andrea" uniqKey="Gehrig A" first="Andrea" last="Gehrig">Andrea Gehrig</name><affiliation><nlm:affiliation>Institute of Human Genetics, University Würzburg, Wurzburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Sutter, Christian" sort="Sutter, Christian" uniqKey="Sutter C" first="Christian" last="Sutter">Christian Sutter</name><affiliation><nlm:affiliation>University Heidelberg, Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Engel, Christoph" sort="Engel, Christoph" uniqKey="Engel C" first="Christoph" last="Engel">Christoph Engel</name><affiliation><nlm:affiliation>Institute for Medical Informatics, Statistics, and Epidemiology, University of Leipzig, Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Niederacher, Dieter" sort="Niederacher, Dieter" uniqKey="Niederacher D" first="Dieter" last="Niederacher">Dieter Niederacher</name><affiliation><nlm:affiliation>University Düsseldorf, Dusseldorf, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Steinemann, Doris" sort="Steinemann, Doris" uniqKey="Steinemann D" first="Doris" last="Steinemann">Doris Steinemann</name><affiliation><nlm:affiliation>Hannover Medical School, Hanover, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Plendl, Hansjoerg" sort="Plendl, Hansjoerg" uniqKey="Plendl H" first="Hansjoerg" last="Plendl">Hansjoerg Plendl</name><affiliation><nlm:affiliation>Institute of Human Genetics, University Hospital of Schleswig-Holstein/University Kiel, Kiel, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kast, Karin" sort="Kast, Karin" uniqKey="Kast K" first="Karin" last="Kast">Karin Kast</name><affiliation><nlm:affiliation>Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Rhiem, Kerstin" sort="Rhiem, Kerstin" uniqKey="Rhiem K" first="Kerstin" last="Rhiem">Kerstin Rhiem</name><affiliation><nlm:affiliation>Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne, Germany. Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Germany. Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Ditsch, Nina" sort="Ditsch, Nina" uniqKey="Ditsch N" first="Nina" last="Ditsch">Nina Ditsch</name><affiliation><nlm:affiliation>Department of Gynaecology and Obstetrics, University Munich, Munich, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name><affiliation><nlm:affiliation>Department of Gynecology and Obstetrics, University Hospital of Schleswig-Holstein/University Kiel, Kiel, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Varon Mateeva, Raymonda" sort="Varon Mateeva, Raymonda" uniqKey="Varon Mateeva R" first="Raymonda" last="Varon-Mateeva">Raymonda Varon-Mateeva</name><affiliation><nlm:affiliation>Institute of Human Genetics, Charite Berlin, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wappenschmidt, Barbara" sort="Wappenschmidt, Barbara" uniqKey="Wappenschmidt B" first="Barbara" last="Wappenschmidt">Barbara Wappenschmidt</name><affiliation><nlm:affiliation>Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne, Germany. Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Germany. Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name><affiliation><nlm:affiliation>Department of Gynaecology and Obstetrics, University Hospital Ulm, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Bressac De Paillerets, Brigitte" sort="Bressac De Paillerets, Brigitte" uniqKey="Bressac De Paillerets B" first="Brigitte" last="Bressac-De Paillerets">Brigitte Bressac-De Paillerets</name><affiliation><nlm:affiliation>INSERM U946, Fondation Jean Dausset, Paris, France. Service de Génétique, Institut de Cancérologie Gustave Roussy, Villejuif, France.</nlm:affiliation></affiliation></author><author><name sortKey="Buecher, Bruno" sort="Buecher, Bruno" uniqKey="Buecher B" first="Bruno" last="Buecher">Bruno Buecher</name><affiliation><nlm:affiliation>Institut Curie, Department of Tumour Biology, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Delnatte, Capucine" sort="Delnatte, Capucine" uniqKey="Delnatte C" first="Capucine" last="Delnatte">Capucine Delnatte</name><affiliation><nlm:affiliation>Centre René Gauducheau, Nantes, France.</nlm:affiliation></affiliation></author><author><name sortKey="Houdayer, Claude" sort="Houdayer, Claude" uniqKey="Houdayer C" first="Claude" last="Houdayer">Claude Houdayer</name><affiliation><nlm:affiliation>Institut Curie, Department of Tumour Biology, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, France.</nlm:affiliation></affiliation></author><author><name sortKey="Stoppa Lyonnet, Dominique" sort="Stoppa Lyonnet, Dominique" uniqKey="Stoppa Lyonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name><affiliation><nlm:affiliation>Institut Curie, Department of Tumour Biology, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, France. Institut Curie, INSERM U830, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Damiola, Francesca" sort="Damiola, Francesca" uniqKey="Damiola F" first="Francesca" last="Damiola">Francesca Damiola</name><affiliation><nlm:affiliation>INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Coupier, Isabelle" sort="Coupier, Isabelle" uniqKey="Coupier I" first="Isabelle" last="Coupier">Isabelle Coupier</name><affiliation><nlm:affiliation>Unité d'Oncogénétique, CHU Arnaud de Villeneuve, Montpellier, France. Unité d'Oncogénétique, CRLCC Val d'Aurelle, Montpellier, France.</nlm:affiliation></affiliation></author><author><name sortKey="Barjhoux, Laure" sort="Barjhoux, Laure" uniqKey="Barjhoux L" first="Laure" last="Barjhoux">Laure Barjhoux</name><affiliation><nlm:affiliation>Unité d'Oncogénétique, CRLCC Val d'Aurelle, Montpellier, France.</nlm:affiliation></affiliation></author><author><name sortKey="Venat Bouvet, Laurence" sort="Venat Bouvet, Laurence" uniqKey="Venat Bouvet L" first="Laurence" last="Venat-Bouvet">Laurence Venat-Bouvet</name><affiliation><nlm:affiliation>Department of Medical Oncology, Centre Hospitalier Universitaire Dupuytren, Limoges, France.</nlm:affiliation></affiliation></author><author><name sortKey="Golmard, Lisa" sort="Golmard, Lisa" uniqKey="Golmard L" first="Lisa" last="Golmard">Lisa Golmard</name><affiliation><nlm:affiliation>Institut Curie, Department of Tumour Biology, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Boutry Kryza, Nadia" sort="Boutry Kryza, Nadia" uniqKey="Boutry Kryza N" first="Nadia" last="Boutry-Kryza">Nadia Boutry-Kryza</name><affiliation><nlm:affiliation>Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon - Centre Léon Bérard, Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Sinilnikova, Olga M" sort="Sinilnikova, Olga M" uniqKey="Sinilnikova O" first="Olga M" last="Sinilnikova">Olga M. Sinilnikova</name><affiliation><nlm:affiliation>INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France. Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon - Centre Léon Bérard, Lyon, France. IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Caron, Olivier" sort="Caron, Olivier" uniqKey="Caron O" first="Olivier" last="Caron">Olivier Caron</name><affiliation><nlm:affiliation>Consultation de Génétique, Département de Médecine, Institut de Cancérologie Gustave Roussy, Villejuif, France.</nlm:affiliation></affiliation></author><author><name sortKey="Pujol, Pascal" sort="Pujol, Pascal" uniqKey="Pujol P" first="Pascal" last="Pujol">Pascal Pujol</name><affiliation><nlm:affiliation>Unité d'Oncogénétique, CHU Arnaud de Villeneuve, Montpellier, France. INSERM 896, CRCM Val d'Aurelle, Montpellier, France.</nlm:affiliation></affiliation></author><author><name sortKey="Mazoyer, Sylvie" sort="Mazoyer, Sylvie" uniqKey="Mazoyer S" first="Sylvie" last="Mazoyer">Sylvie Mazoyer</name><affiliation><nlm:affiliation>INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Belotti, Muriel" sort="Belotti, Muriel" uniqKey="Belotti M" first="Muriel" last="Belotti">Muriel Belotti</name><affiliation><nlm:affiliation>Institut Curie, Department of Tumour Biology, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Piedmonte, Marion" sort="Piedmonte, Marion" uniqKey="Piedmonte M" first="Marion" last="Piedmonte">Marion Piedmonte</name><affiliation><nlm:affiliation>Gynecologic Oncology Group Statistical and Data Center, Roswell Park Cancer Institute, Buffalo, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Friedlander, Michael L" sort="Friedlander, Michael L" uniqKey="Friedlander M" first="Michael L" last="Friedlander">Michael L. Friedlander</name><affiliation><nlm:affiliation>Australia New Zealand Gynaecological Oncology Group (ANZGOG), Coordinating Centre, Camperdown, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Rodriguez, Gustavo C" sort="Rodriguez, Gustavo C" uniqKey="Rodriguez G" first="Gustavo C" last="Rodriguez">Gustavo C. Rodriguez</name><affiliation><nlm:affiliation>Division of Gynecologic Oncology, NorthShore University HealthSystem, Evanston, Illinois.</nlm:affiliation></affiliation></author><author><name sortKey="Copeland, Larry J" sort="Copeland, Larry J" uniqKey="Copeland L" first="Larry J" last="Copeland">Larry J. Copeland</name><affiliation><nlm:affiliation>Ohio State University, Department of Obstetrics and Gynecology, Hilliard, Ohio.</nlm:affiliation></affiliation></author><author><name sortKey="De La Hoya, Miguel" sort="De La Hoya, Miguel" uniqKey="De La Hoya M" first="Miguel" last="De La Hoya">Miguel De La Hoya</name><affiliation><nlm:affiliation>Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Segura, Pedro Perez" sort="Segura, Pedro Perez" uniqKey="Segura P" first="Pedro Perez" last="Segura">Pedro Perez Segura</name><affiliation><nlm:affiliation>Department of Oncology, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland. University of Helsinki, Helsinki, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Van Os, Theo A M" sort="Van Os, Theo A M" uniqKey="Van Os T" first="Theo A M" last="Van Os">Theo A M. Van Os</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Meijers Heijboer, Hanne E J" sort="Meijers Heijboer, Hanne E J" uniqKey="Meijers Heijboer H" first="Hanne E J" last="Meijers-Heijboer">Hanne E J. Meijers-Heijboer</name><affiliation><nlm:affiliation>Department of Clinical Genetics, VU University Medical Centre, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Van Der Hout, Annemarie H" sort="Van Der Hout, Annemarie H" uniqKey="Van Der Hout A" first="Annemarie H" last="Van Der Hout">Annemarie H. Van Der Hout</name><affiliation><nlm:affiliation>Department of Genetics, University Medical Center, Groningen University, Groningen, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Vreeswijk, Maaike P G" sort="Vreeswijk, Maaike P G" uniqKey="Vreeswijk M" first="Maaike P G" last="Vreeswijk">Maaike P G. Vreeswijk</name><affiliation><nlm:affiliation>Department of Human Genetics, Leiden University Medical Center (LUMC), Leiden, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Hoogerbrugge, Nicoline" sort="Hoogerbrugge, Nicoline" uniqKey="Hoogerbrugge N" first="Nicoline" last="Hoogerbrugge">Nicoline Hoogerbrugge</name><affiliation><nlm:affiliation>Department of Human Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Ausems, Margreet G E M" sort="Ausems, Margreet G E M" uniqKey="Ausems M" first="Margreet G E M" last="Ausems">Margreet G E M. Ausems</name><affiliation><nlm:affiliation>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Van Doorn, Helena C" sort="Van Doorn, Helena C" uniqKey="Van Doorn H" first="Helena C" last="Van Doorn">Helena C. Van Doorn</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Erasmus University MC Cancer Institute, Rotterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Collee, J Margriet" sort="Collee, J Margriet" uniqKey="Collee J" first="J Margriet" last="Collée">J Margriet Collée</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Olah, Edith" sort="Olah, Edith" uniqKey="Olah E" first="Edith" last="Olah">Edith Olah</name><affiliation><nlm:affiliation>Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary.</nlm:affiliation></affiliation></author><author><name sortKey="Diez, Orland" sort="Diez, Orland" uniqKey="Diez O" first="Orland" last="Diez">Orland Diez</name><affiliation><nlm:affiliation>Oncogenetics Group, University Hospital Vall d'Hebron, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Blanco, Ignacio" sort="Blanco, Ignacio" uniqKey="Blanco I" first="Ignacio" last="Blanco">Ignacio Blanco</name><affiliation><nlm:affiliation>Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Lazaro, Conxi" sort="Lazaro, Conxi" uniqKey="Lazaro C" first="Conxi" last="Lazaro">Conxi Lazaro</name><affiliation><nlm:affiliation>Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Brunet, Joan" sort="Brunet, Joan" uniqKey="Brunet J" first="Joan" last="Brunet">Joan Brunet</name><affiliation><nlm:affiliation>Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI-Catalan Institute of Oncology, Girona, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Feliubadalo, Lidia" sort="Feliubadalo, Lidia" uniqKey="Feliubadalo L" first="Lidia" last="Feliubadalo">Lidia Feliubadalo</name><affiliation><nlm:affiliation>BMC, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Cybulski, Cezary" sort="Cybulski, Cezary" uniqKey="Cybulski C" first="Cezary" last="Cybulski">Cezary Cybulski</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Jaworska Bieniek, Katarzyna" sort="Jaworska Bieniek, Katarzyna" uniqKey="Jaworska Bieniek K" first="Katarzyna" last="Jaworska-Bieniek">Katarzyna Jaworska-Bieniek</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Sukiennicki, Grzegorz" sort="Sukiennicki, Grzegorz" uniqKey="Sukiennicki G" first="Grzegorz" last="Sukiennicki">Grzegorz Sukiennicki</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Arason, Adalgeir" sort="Arason, Adalgeir" uniqKey="Arason A" first="Adalgeir" last="Arason">Adalgeir Arason</name><affiliation><nlm:affiliation>BMC, Faculty of Medicine, University of Iceland, Reykjavik, Iceland. Department of Pathology, Landspitali University Hospital, Reykjavik, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Chiquette, Jocelyne" sort="Chiquette, Jocelyne" uniqKey="Chiquette J" first="Jocelyne" last="Chiquette">Jocelyne Chiquette</name><affiliation><nlm:affiliation>Unité de Recherche en Santé des Populations, Centre des Maladies du Sein Deschênes-Fabia, Centre de Recherche FRSQ du Centre Hospitalier Affilié Universitaire de Québec, Québec, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Teixeira, Manuel R" sort="Teixeira, Manuel R" uniqKey="Teixeira M" first="Manuel R" last="Teixeira">Manuel R. Teixeira</name><affiliation><nlm:affiliation>Biomedical Sciences Institute (ICBAS), Porto University, Porto, Portugal. Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.</nlm:affiliation></affiliation></author><author><name sortKey="Olswold, Curtis" sort="Olswold, Curtis" uniqKey="Olswold C" first="Curtis" last="Olswold">Curtis Olswold</name><affiliation><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnessotta.</nlm:affiliation></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J" last="Couch">Fergus J. Couch</name><affiliation><nlm:affiliation>Department of Laboratory Medicine and Pathology, and Health Sciences Research, Mayo Clinic, Rochester, Minnessotta.</nlm:affiliation></affiliation></author><author><name sortKey="Lindor, Noralane M" sort="Lindor, Noralane M" uniqKey="Lindor N" first="Noralane M" last="Lindor">Noralane M. Lindor</name><affiliation><nlm:affiliation>Health Sciences Research, Mayo Clinic, Scottsdale, Arizona.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation><nlm:affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnessotta.</nlm:affiliation></affiliation></author><author><name sortKey="Szabo, Csilla I" sort="Szabo, Csilla I" uniqKey="Szabo C" first="Csilla I" last="Szabo">Csilla I. Szabo</name><affiliation><nlm:affiliation>National Human Genome Research Institute, NIH, Bethesda, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name><affiliation><nlm:affiliation>Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Corines, Marina" sort="Corines, Marina" uniqKey="Corines M" first="Marina" last="Corines">Marina Corines</name><affiliation><nlm:affiliation>Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Jacobs, Lauren" sort="Jacobs, Lauren" uniqKey="Jacobs L" first="Lauren" last="Jacobs">Lauren Jacobs</name><affiliation><nlm:affiliation>Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Robson, Mark E" sort="Robson, Mark E" uniqKey="Robson M" first="Mark E" last="Robson">Mark E. Robson</name><affiliation><nlm:affiliation>Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Zhang, Liying" sort="Zhang, Liying" uniqKey="Zhang L" first="Liying" last="Zhang">Liying Zhang</name><affiliation><nlm:affiliation>Diagnostic Molecular Genetics Laboratory, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Joseph, Vijai" sort="Joseph, Vijai" uniqKey="Joseph V" first="Vijai" last="Joseph">Vijai Joseph</name><affiliation><nlm:affiliation>Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Berger, Andreas" sort="Berger, Andreas" uniqKey="Berger A" first="Andreas" last="Berger">Andreas Berger</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Singer, Christian F" sort="Singer, Christian F" uniqKey="Singer C" first="Christian F" last="Singer">Christian F. Singer</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Rappaport, Christine" sort="Rappaport, Christine" uniqKey="Rappaport C" first="Christine" last="Rappaport">Christine Rappaport</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Kaulich, Daphne Geschwantler" sort="Kaulich, Daphne Geschwantler" uniqKey="Kaulich D" first="Daphne Geschwantler" last="Kaulich">Daphne Geschwantler Kaulich</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Pfeiler, Georg" sort="Pfeiler, Georg" uniqKey="Pfeiler G" first="Georg" last="Pfeiler">Georg Pfeiler</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Tea, Muy Kheng M" sort="Tea, Muy Kheng M" uniqKey="Tea M" first="Muy-Kheng M" last="Tea">Muy-Kheng M. Tea</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Phelan, Catherine M" sort="Phelan, Catherine M" uniqKey="Phelan C" first="Catherine M" last="Phelan">Catherine M. Phelan</name><affiliation><nlm:affiliation>Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida.</nlm:affiliation></affiliation></author><author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H" last="Greene">Mark H. Greene</name><affiliation><nlm:affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Mai, Phuong L" sort="Mai, Phuong L" uniqKey="Mai P" first="Phuong L" last="Mai">Phuong L. Mai</name><affiliation><nlm:affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Rennert, Gad" sort="Rennert, Gad" uniqKey="Rennert G" first="Gad" last="Rennert">Gad Rennert</name><affiliation><nlm:affiliation>Clalit National Cancer Control Center, Haifa, Israel.</nlm:affiliation></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation><nlm:affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation><nlm:affiliation>Ontario Cancer Genetics Network: Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Tchatchou, Sandrine" sort="Tchatchou, Sandrine" uniqKey="Tchatchou S" first="Sandrine" last="Tchatchou">Sandrine Tchatchou</name><affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name><affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Toland, Amanda Ewart" sort="Toland, Amanda Ewart" uniqKey="Toland A" first="Amanda Ewart" last="Toland">Amanda Ewart Toland</name><affiliation><nlm:affiliation>Division of Human Cancer Genetics, Departments of Internal Medicine and Molecular Virology, Immunology, and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.</nlm:affiliation></affiliation></author><author><name sortKey="Bojesen, Anders" sort="Bojesen, Anders" uniqKey="Bojesen A" first="Anders" last="Bojesen">Anders Bojesen</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Pedersen, Inge Sokilde" sort="Pedersen, Inge Sokilde" uniqKey="Pedersen I" first="Inge Sokilde" last="Pedersen">Inge Sokilde Pedersen</name><affiliation><nlm:affiliation>Section of Molecular Diagnostics, Department of Biochemistry, Aalborg University Hospital, Aalborg, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Thomassen, Mads" sort="Thomassen, Mads" uniqKey="Thomassen M" first="Mads" last="Thomassen">Mads Thomassen</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Jensen, Uffe Birk" sort="Jensen, Uffe Birk" uniqKey="Jensen U" first="Uffe Birk" last="Jensen">Uffe Birk Jensen</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Laitman, Yael" sort="Laitman, Yael" uniqKey="Laitman Y" first="Yael" last="Laitman">Yael Laitman</name><affiliation><nlm:affiliation>Sheba Medical Center, Tel Aviv, Israel.</nlm:affiliation></affiliation></author><author><name sortKey="Rantala, Johanna" sort="Rantala, Johanna" uniqKey="Rantala J" first="Johanna" last="Rantala">Johanna Rantala</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Von Wachenfeldt, Anna" sort="Von Wachenfeldt, Anna" uniqKey="Von Wachenfeldt A" first="Anna" last="Von Wachenfeldt">Anna Von Wachenfeldt</name><affiliation><nlm:affiliation>Department of Oncology, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Ehrencrona, Hans" sort="Ehrencrona, Hans" uniqKey="Ehrencrona H" first="Hans" last="Ehrencrona">Hans Ehrencrona</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Lund University Hospital, Lund, Sweden. Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Askmalm, Marie Stenmark" sort="Askmalm, Marie Stenmark" uniqKey="Askmalm M" first="Marie Stenmark" last="Askmalm">Marie Stenmark Askmalm</name><affiliation><nlm:affiliation>Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Borg, Ke" sort="Borg, Ke" uniqKey="Borg " first=" Ke" last="Borg"> Ke Borg</name><affiliation><nlm:affiliation>Department of Oncology, Lund University, Lund, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Kuchenbaecker, Karoline B" sort="Kuchenbaecker, Karoline B" uniqKey="Kuchenbaecker K" first="Karoline B" last="Kuchenbaecker">Karoline B. Kuchenbaecker</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Mcguffog, Lesley" sort="Mcguffog, Lesley" uniqKey="Mcguffog L" first="Lesley" last="Mcguffog">Lesley Mcguffog</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Barrowdale, Daniel" sort="Barrowdale, Daniel" uniqKey="Barrowdale D" first="Daniel" last="Barrowdale">Daniel Barrowdale</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Healey, Sue" sort="Healey, Sue" uniqKey="Healey S" first="Sue" last="Healey">Sue Healey</name><affiliation><nlm:affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Lee, Andrew" sort="Lee, Andrew" uniqKey="Lee A" first="Andrew" last="Lee">Andrew Lee</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D P" last="Pharoah">Paul D P. Pharoah</name><affiliation><nlm:affiliation>Department of Oncology, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation><nlm:affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C" last="Antoniou">Antonis C. Antoniou</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Friedman, Eitan" sort="Friedman, Eitan" uniqKey="Friedman E" first="Eitan" last="Friedman">Eitan Friedman</name><affiliation><nlm:affiliation>Sheba Medical Center, Tel Aviv, Israel. paolo.peterlongo@ifom.eu eitan.friedman@sheba.health.gov.il feitan@post.tau.ac.il.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:25336561</idno><idno type="pmid">25336561</idno><idno type="doi">10.1158/1055-9965.EPI-14-0532</idno><idno type="wicri:Area/PubMed/Corpus">003196</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003196</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.</title><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation><nlm:affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy. paolo.peterlongo@ifom.eu eitan.friedman@sheba.health.gov.il feitan@post.tau.ac.il.</nlm:affiliation></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Moysich, Kirsten B" sort="Moysich, Kirsten B" uniqKey="Moysich K" first="Kirsten B" last="Moysich">Kirsten B. Moysich</name><affiliation><nlm:affiliation>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name><affiliation><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K" last="Schmutzler">Rita K. Schmutzler</name><affiliation><nlm:affiliation>Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne, Germany. Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Germany. Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany, on behalf of the German Consortium of Hereditary Breast and Ovarian Cancer (GC-HBOC).</nlm:affiliation></affiliation></author><author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name><affiliation><nlm:affiliation>Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Soucy, Penny" sort="Soucy, Penny" uniqKey="Soucy P" first="Penny" last="Soucy">Penny Soucy</name><affiliation><nlm:affiliation>Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Eeles, Rosalind A" sort="Eeles, Rosalind A" uniqKey="Eeles R" first="Rosalind A" last="Eeles">Rosalind A. Eeles</name><affiliation><nlm:affiliation>Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Surrey, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F" last="Easton">Douglas F. Easton</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation><nlm:affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wilkening, Stefan" sort="Wilkening, Stefan" uniqKey="Wilkening S" first="Stefan" last="Wilkening">Stefan Wilkening</name><affiliation><nlm:affiliation>Genomic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Chen, Bowang" sort="Chen, Bowang" uniqKey="Chen B" first="Bowang" last="Chen">Bowang Chen</name><affiliation><nlm:affiliation>Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Rookus, Matti A" sort="Rookus, Matti A" uniqKey="Rookus M" first="Matti A" last="Rookus">Matti A. Rookus</name><affiliation><nlm:affiliation>Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K" last="Schmidt">Marjanka K. Schmidt</name><affiliation><nlm:affiliation>Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Van Der Baan, Frederieke H" sort="Van Der Baan, Frederieke H" uniqKey="Van Der Baan F" first="Frederieke H" last="Van Der Baan">Frederieke H. Van Der Baan</name><affiliation><nlm:affiliation>Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B" last="Spurdle">Amanda B. Spurdle</name><affiliation><nlm:affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Walker, Logan C" sort="Walker, Logan C" uniqKey="Walker L" first="Logan C" last="Walker">Logan C. Walker</name><affiliation><nlm:affiliation>Department of Pathology, University of Otago, Christchurch, New Zealand.</nlm:affiliation></affiliation></author><author><name sortKey="Lose, Felicity" sort="Lose, Felicity" uniqKey="Lose F" first="Felicity" last="Lose">Felicity Lose</name><affiliation><nlm:affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Maia, Ana Teresa" sort="Maia, Ana Teresa" uniqKey="Maia A" first="Ana-Teresa" last="Maia">Ana-Teresa Maia</name><affiliation><nlm:affiliation>Department of Biomedical Sciences and Medicine, Gambelas Campus, University of Algarve, Portugal.</nlm:affiliation></affiliation></author><author><name sortKey="Montagna, Marco" sort="Montagna, Marco" uniqKey="Montagna M" first="Marco" last="Montagna">Marco Montagna</name><affiliation><nlm:affiliation>Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV - IRCCS, Padua, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Matricardi, Laura" sort="Matricardi, Laura" uniqKey="Matricardi L" first="Laura" last="Matricardi">Laura Matricardi</name><affiliation><nlm:affiliation>Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV - IRCCS, Padua, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="G Mez Garcia, Encarna B" sort="G Mez Garcia, Encarna B" uniqKey="G Mez Garcia E" first="Encarna B" last="G Mez Garcia">Encarna B. G Mez Garcia</name><affiliation><nlm:affiliation>Department of Clinical Genetics, MUMC, Maastricht, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Olopade, Olufunmilayo I" sort="Olopade, Olufunmilayo I" uniqKey="Olopade O" first="Olufunmilayo I" last="Olopade">Olufunmilayo I. Olopade</name><affiliation><nlm:affiliation>Center for Clinical Cancer Genetics, Department of Medicine and Human Genetics, University of Chicago Medical Center, Chicago, Illinois.</nlm:affiliation></affiliation></author><author><name sortKey="Nussbaum, Robert L" sort="Nussbaum, Robert L" uniqKey="Nussbaum R" first="Robert L" last="Nussbaum">Robert L. Nussbaum</name><affiliation><nlm:affiliation>Department of Medicine and Institute for Human Genetics, University of California, San Francisco, San Francisco, California.</nlm:affiliation></affiliation></author><author><name sortKey="Nathanson, Katherine L" sort="Nathanson, Katherine L" uniqKey="Nathanson K" first="Katherine L" last="Nathanson">Katherine L. Nathanson</name><affiliation><nlm:affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadephia, Pennsylvania.</nlm:affiliation></affiliation></author><author><name sortKey="Domchek, Susan M" sort="Domchek, Susan M" uniqKey="Domchek S" first="Susan M" last="Domchek">Susan M. Domchek</name><affiliation><nlm:affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadephia, Pennsylvania.</nlm:affiliation></affiliation></author><author><name sortKey="Rebbeck, Timothy R" sort="Rebbeck, Timothy R" uniqKey="Rebbeck T" first="Timothy R" last="Rebbeck">Timothy R. Rebbeck</name><affiliation><nlm:affiliation>Department of Epidemiology and Biostatistics, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadephia, Pennsylvania.</nlm:affiliation></affiliation></author><author><name sortKey="Arun, Banu K" sort="Arun, Banu K" uniqKey="Arun B" first="Banu K" last="Arun">Banu K. Arun</name><affiliation><nlm:affiliation>University of Texas MD Anderson Cancer Center, Houston, Texas.</nlm:affiliation></affiliation></author><author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y" last="Karlan">Beth Y. Karlan</name><affiliation><nlm:affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.</nlm:affiliation></affiliation></author><author><name sortKey="Orsulic, Sandra" sort="Orsulic, Sandra" uniqKey="Orsulic S" first="Sandra" last="Orsulic">Sandra Orsulic</name><affiliation><nlm:affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.</nlm:affiliation></affiliation></author><author><name sortKey="Lester, Jenny" sort="Lester, Jenny" uniqKey="Lester J" first="Jenny" last="Lester">Jenny Lester</name><affiliation><nlm:affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.</nlm:affiliation></affiliation></author><author><name sortKey="Chung, Wendy K" sort="Chung, Wendy K" uniqKey="Chung W" first="Wendy K" last="Chung">Wendy K. Chung</name><affiliation><nlm:affiliation>Departments of Pediatrics and Medicine, Columbia University, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Miron, Alex" sort="Miron, Alex" uniqKey="Miron A" first="Alex" last="Miron">Alex Miron</name><affiliation><nlm:affiliation>Department of Genetics and Genomics at Case Western Reserve Medical School, Cleveland, Ohio.</nlm:affiliation></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C" last="Southey">Melissa C. Southey</name><affiliation><nlm:affiliation>Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Goldgar, David E" sort="Goldgar, David E" uniqKey="Goldgar D" first="David E" last="Goldgar">David E. Goldgar</name><affiliation><nlm:affiliation>Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah.</nlm:affiliation></affiliation></author><author><name sortKey="Buys, Saundra S" sort="Buys, Saundra S" uniqKey="Buys S" first="Saundra S" last="Buys">Saundra S. Buys</name><affiliation><nlm:affiliation>Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah.</nlm:affiliation></affiliation></author><author><name sortKey="Janavicius, Ramunas" sort="Janavicius, Ramunas" uniqKey="Janavicius R" first="Ramunas" last="Janavicius">Ramunas Janavicius</name><affiliation><nlm:affiliation>Vilnius University Hospital Santariskiu Clinics, Hematology, Oncology, and Transfusion Medicine Center, Dept. of Molecular and Regenerative Medicine; State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania.</nlm:affiliation></affiliation></author><author><name sortKey="Dorfling, Cecilia M" sort="Dorfling, Cecilia M" uniqKey="Dorfling C" first="Cecilia M" last="Dorfling">Cecilia M. Dorfling</name><affiliation><nlm:affiliation>Department of Genetics, University of Pretoria, Pretoria, South Africa.</nlm:affiliation></affiliation></author><author><name sortKey="Van Rensburg, Elizabeth J" sort="Van Rensburg, Elizabeth J" uniqKey="Van Rensburg E" first="Elizabeth J" last="Van Rensburg">Elizabeth J. Van Rensburg</name><affiliation><nlm:affiliation>Department of Genetics, University of Pretoria, Pretoria, South Africa.</nlm:affiliation></affiliation></author><author><name sortKey="Ding, Yuan Chun" sort="Ding, Yuan Chun" uniqKey="Ding Y" first="Yuan Chun" last="Ding">Yuan Chun Ding</name><affiliation><nlm:affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California.</nlm:affiliation></affiliation></author><author><name sortKey="Neuhausen, Susan L" sort="Neuhausen, Susan L" uniqKey="Neuhausen S" first="Susan L" last="Neuhausen">Susan L. Neuhausen</name><affiliation><nlm:affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California.</nlm:affiliation></affiliation></author><author><name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V O" last="Hansen">Thomas V O. Hansen</name><affiliation><nlm:affiliation>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Gerdes, Anne Marie" sort="Gerdes, Anne Marie" uniqKey="Gerdes A" first="Anne-Marie" last="Gerdes">Anne-Marie Gerdes</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name><affiliation><nlm:affiliation>Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="J Nson, Lars" sort="J Nson, Lars" uniqKey="J Nson L" first="Lars" last="J Nson">Lars J Nson</name><affiliation><nlm:affiliation>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Osorio, Ana" sort="Osorio, Ana" uniqKey="Osorio A" first="Ana" last="Osorio">Ana Osorio</name><affiliation><nlm:affiliation>Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Martinez Bouzas, Cristina" sort="Martinez Bouzas, Cristina" uniqKey="Martinez Bouzas C" first="Cristina" last="Martínez-Bouzas">Cristina Martínez-Bouzas</name><affiliation><nlm:affiliation>Molecular Genetics Laboratory, Department of Biochemistry, Cruces Hospital Barakaldo, 48903-Barakaldo-Bizkaia, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><affiliation><nlm:affiliation>Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. Human Genetics Group and Genotyping Unit, Spanish National Cancer Centre (CNIO), Madrid, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Conway, Edye E" sort="Conway, Edye E" uniqKey="Conway E" first="Edye E" last="Conway">Edye E. Conway</name><affiliation><nlm:affiliation>Saint Alphonsus Regional Medical Center, care of City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California.</nlm:affiliation></affiliation></author><author><name sortKey="Blazer, Kathleen R" sort="Blazer, Kathleen R" uniqKey="Blazer K" first="Kathleen R" last="Blazer">Kathleen R. Blazer</name><affiliation><nlm:affiliation>Clinical Cancer Genetics, City of Hope, Duarte, California.</nlm:affiliation></affiliation></author><author><name sortKey="Weitzel, Jeffrey N" sort="Weitzel, Jeffrey N" uniqKey="Weitzel J" first="Jeffrey N" last="Weitzel">Jeffrey N. Weitzel</name><affiliation><nlm:affiliation>Clinical Cancer Genetics, City of Hope, Duarte, California (for the City of Hope Clinical Cancer Genetics Community Research Network).</nlm:affiliation></affiliation></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name><affiliation><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name><affiliation><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Zaffaroni, Daniela" sort="Zaffaroni, Daniela" uniqKey="Zaffaroni D" first="Daniela" last="Zaffaroni">Daniela Zaffaroni</name><affiliation><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Scuvera, Giulietta" sort="Scuvera, Giulietta" uniqKey="Scuvera G" first="Giulietta" last="Scuvera">Giulietta Scuvera</name><affiliation><nlm:affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Barile, Monica" sort="Barile, Monica" uniqKey="Barile M" first="Monica" last="Barile">Monica Barile</name><affiliation><nlm:affiliation>Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Ficarazzi, Filomena" sort="Ficarazzi, Filomena" uniqKey="Ficarazzi F" first="Filomena" last="Ficarazzi">Filomena Ficarazzi</name><affiliation><nlm:affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Cogentech Cancer Genetic Test Laboratory, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Mariette, Frederique" sort="Mariette, Frederique" uniqKey="Mariette F" first="Frederique" last="Mariette">Frederique Mariette</name><affiliation><nlm:affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Cogentech Cancer Genetic Test Laboratory, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Fortuzzi, Stefano" sort="Fortuzzi, Stefano" uniqKey="Fortuzzi S" first="Stefano" last="Fortuzzi">Stefano Fortuzzi</name><affiliation><nlm:affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Cogentech Cancer Genetic Test Laboratory, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Viel, Alessandra" sort="Viel, Alessandra" uniqKey="Viel A" first="Alessandra" last="Viel">Alessandra Viel</name><affiliation><nlm:affiliation>Division of Experimental Oncology 1, CRO Aviano National Cancer Institute, Aviano (PN), Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Giannini, Giuseppe" sort="Giannini, Giuseppe" uniqKey="Giannini G" first="Giuseppe" last="Giannini">Giuseppe Giannini</name><affiliation><nlm:affiliation>Department of Molecular Medicine, Sapienza University, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Papi, Laura" sort="Papi, Laura" uniqKey="Papi L" first="Laura" last="Papi">Laura Papi</name><affiliation><nlm:affiliation>Unit of Medical Genetics, Department of Biomedical, Experimental, and Clinical Sciences, University of Florence, Florence, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Martayan, Aline" sort="Martayan, Aline" uniqKey="Martayan A" first="Aline" last="Martayan">Aline Martayan</name><affiliation><nlm:affiliation>Unit of Genetic Counseling, Medical Oncology Department, Istituto Nazionale Tumori Regina Elena, Rome, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Tibiletti, Maria Grazia" sort="Tibiletti, Maria Grazia" uniqKey="Tibiletti M" first="Maria Grazia" last="Tibiletti">Maria Grazia Tibiletti</name><affiliation><nlm:affiliation>UO Anatomia Patologica Ospedale di Circolo e Fondazione Macchi, Polo Universitario Varese, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation><nlm:affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Vratimos, Athanassios" sort="Vratimos, Athanassios" uniqKey="Vratimos A" first="Athanassios" last="Vratimos">Athanassios Vratimos</name><affiliation><nlm:affiliation>Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens, Greece.</nlm:affiliation></affiliation></author><author><name sortKey="Fostira, Florentia" sort="Fostira, Florentia" uniqKey="Fostira F" first="Florentia" last="Fostira">Florentia Fostira</name><affiliation><nlm:affiliation>Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens, Greece.</nlm:affiliation></affiliation></author><author><name sortKey="Garber, Judy E" sort="Garber, Judy E" uniqKey="Garber J" first="Judy E" last="Garber">Judy E. Garber</name><affiliation><nlm:affiliation>Dana-Farber Cancer Institute, Boston, Massachuestts.</nlm:affiliation></affiliation></author><author><name sortKey="Donaldson, Alan" sort="Donaldson, Alan" uniqKey="Donaldson A" first="Alan" last="Donaldson">Alan Donaldson</name><affiliation><nlm:affiliation>Clinical Genetics Department, St. Michael's Hospital, Bristol, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Brewer, Carole" sort="Brewer, Carole" uniqKey="Brewer C" first="Carole" last="Brewer">Carole Brewer</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Royal Devon & Exeter Hospital, Exeter, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Foo, Claire" sort="Foo, Claire" uniqKey="Foo C" first="Claire" last="Foo">Claire Foo</name><affiliation><nlm:affiliation>Cheshire & Merseyside Clinical Genetics Service, Liverpool Women's NHS Foundation Trust, Liverpool, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Evans, D Gareth R" sort="Evans, D Gareth R" uniqKey="Evans D" first="D Gareth R" last="Evans">D Gareth R. Evans</name><affiliation><nlm:affiliation>Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Frost, Debra" sort="Frost, Debra" uniqKey="Frost D" first="Debra" last="Frost">Debra Frost</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name><affiliation><nlm:affiliation>University of Southampton, Faculty of Medicine, Southampton University Hospitals NHS Trust, Southampton, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Brady, Angela" sort="Brady, Angela" uniqKey="Brady A" first="Angela" last="Brady">Angela Brady</name><affiliation><nlm:affiliation>North West Thames Regional Genetics Service, Kennedy-Galton Centre, Harrow, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Cook, Jackie" sort="Cook, Jackie" uniqKey="Cook J" first="Jackie" last="Cook">Jackie Cook</name><affiliation><nlm:affiliation>Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Tischkowitz, Marc" sort="Tischkowitz, Marc" uniqKey="Tischkowitz M" first="Marc" last="Tischkowitz">Marc Tischkowitz</name><affiliation><nlm:affiliation>Department of Clinical Genetics, East Anglian Regional Genetics Service, Addenbrookes Hospital, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name><affiliation><nlm:affiliation>Yorkshire Regional Genetics Service, Leeds, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Barwell, Julian" sort="Barwell, Julian" uniqKey="Barwell J" first="Julian" last="Barwell">Julian Barwell</name><affiliation><nlm:affiliation>Leicestershire Clinical Genetics Service, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Walker, Lisa" sort="Walker, Lisa" uniqKey="Walker L" first="Lisa" last="Walker">Lisa Walker</name><affiliation><nlm:affiliation>Oxford Regional Genetics Service, Churchill Hospital, Oxford, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Izatt, Louise" sort="Izatt, Louise" uniqKey="Izatt L" first="Louise" last="Izatt">Louise Izatt</name><affiliation><nlm:affiliation>Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Side, Lucy E" sort="Side, Lucy E" uniqKey="Side L" first="Lucy E" last="Side">Lucy E. Side</name><affiliation><nlm:affiliation>North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Kennedy, M John" sort="Kennedy, M John" uniqKey="Kennedy M" first="M John" last="Kennedy">M John Kennedy</name><affiliation><nlm:affiliation>Academic Unit of Clinical and Molecular Oncology, Trinity College Dublin, Ireland. St. James's Hospital, Dublin, Ireland.</nlm:affiliation></affiliation></author><author><name sortKey="Rogers, Mark T" sort="Rogers, Mark T" uniqKey="Rogers M" first="Mark T" last="Rogers">Mark T. Rogers</name><affiliation><nlm:affiliation>All Wales Medical Genetics Services, University Hospital of Wales, Cardiff, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Porteous, Mary E" sort="Porteous, Mary E" uniqKey="Porteous M" first="Mary E" last="Porteous">Mary E. Porteous</name><affiliation><nlm:affiliation>South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Morrison, Patrick J" sort="Morrison, Patrick J" uniqKey="Morrison P" first="Patrick J" last="Morrison">Patrick J. Morrison</name><affiliation><nlm:affiliation>Centre for Cancer Research and Cell Biology, Queens University of Belfast, Department of Medical Genetics, Belfast HSC Trust, Belfast, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Platte, Radka" sort="Platte, Radka" uniqKey="Platte R" first="Radka" last="Platte">Radka Platte</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Davidson, Rosemarie" sort="Davidson, Rosemarie" uniqKey="Davidson R" first="Rosemarie" last="Davidson">Rosemarie Davidson</name><affiliation><nlm:affiliation>West of Scotland Regional Genetics Service, Southern General Hospital, Glasgow, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Hodgson, Shirley V" sort="Hodgson, Shirley V" uniqKey="Hodgson S" first="Shirley V" last="Hodgson">Shirley V. Hodgson</name><affiliation><nlm:affiliation>Medical Genetics Unit, St. George's, University of London, London, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Ellis, Steve" sort="Ellis, Steve" uniqKey="Ellis S" first="Steve" last="Ellis">Steve Ellis</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Cole, Trevor" sort="Cole, Trevor" uniqKey="Cole T" first="Trevor" last="Cole">Trevor Cole</name><affiliation><nlm:affiliation>West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K" last="Godwin">Andrew K. Godwin</name><affiliation><nlm:affiliation>Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Missouri.</nlm:affiliation></affiliation></author><author><name sortKey="Claes, Kathleen" sort="Claes, Kathleen" uniqKey="Claes K" first="Kathleen" last="Claes">Kathleen Claes</name><affiliation><nlm:affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Van Maerken, Tom" sort="Van Maerken, Tom" uniqKey="Van Maerken T" first="Tom" last="Van Maerken">Tom Van Maerken</name><affiliation><nlm:affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation><nlm:affiliation>Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University Munich, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Gehrig, Andrea" sort="Gehrig, Andrea" uniqKey="Gehrig A" first="Andrea" last="Gehrig">Andrea Gehrig</name><affiliation><nlm:affiliation>Institute of Human Genetics, University Würzburg, Wurzburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Sutter, Christian" sort="Sutter, Christian" uniqKey="Sutter C" first="Christian" last="Sutter">Christian Sutter</name><affiliation><nlm:affiliation>University Heidelberg, Heidelberg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Engel, Christoph" sort="Engel, Christoph" uniqKey="Engel C" first="Christoph" last="Engel">Christoph Engel</name><affiliation><nlm:affiliation>Institute for Medical Informatics, Statistics, and Epidemiology, University of Leipzig, Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Niederacher, Dieter" sort="Niederacher, Dieter" uniqKey="Niederacher D" first="Dieter" last="Niederacher">Dieter Niederacher</name><affiliation><nlm:affiliation>University Düsseldorf, Dusseldorf, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Steinemann, Doris" sort="Steinemann, Doris" uniqKey="Steinemann D" first="Doris" last="Steinemann">Doris Steinemann</name><affiliation><nlm:affiliation>Hannover Medical School, Hanover, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Plendl, Hansjoerg" sort="Plendl, Hansjoerg" uniqKey="Plendl H" first="Hansjoerg" last="Plendl">Hansjoerg Plendl</name><affiliation><nlm:affiliation>Institute of Human Genetics, University Hospital of Schleswig-Holstein/University Kiel, Kiel, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kast, Karin" sort="Kast, Karin" uniqKey="Kast K" first="Karin" last="Kast">Karin Kast</name><affiliation><nlm:affiliation>Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Rhiem, Kerstin" sort="Rhiem, Kerstin" uniqKey="Rhiem K" first="Kerstin" last="Rhiem">Kerstin Rhiem</name><affiliation><nlm:affiliation>Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne, Germany. Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Germany. Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Ditsch, Nina" sort="Ditsch, Nina" uniqKey="Ditsch N" first="Nina" last="Ditsch">Nina Ditsch</name><affiliation><nlm:affiliation>Department of Gynaecology and Obstetrics, University Munich, Munich, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name><affiliation><nlm:affiliation>Department of Gynecology and Obstetrics, University Hospital of Schleswig-Holstein/University Kiel, Kiel, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Varon Mateeva, Raymonda" sort="Varon Mateeva, Raymonda" uniqKey="Varon Mateeva R" first="Raymonda" last="Varon-Mateeva">Raymonda Varon-Mateeva</name><affiliation><nlm:affiliation>Institute of Human Genetics, Charite Berlin, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wappenschmidt, Barbara" sort="Wappenschmidt, Barbara" uniqKey="Wappenschmidt B" first="Barbara" last="Wappenschmidt">Barbara Wappenschmidt</name><affiliation><nlm:affiliation>Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne, Germany. Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Germany. Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wang Gohrke, Shan" sort="Wang Gohrke, Shan" uniqKey="Wang Gohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name><affiliation><nlm:affiliation>Department of Gynaecology and Obstetrics, University Hospital Ulm, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Bressac De Paillerets, Brigitte" sort="Bressac De Paillerets, Brigitte" uniqKey="Bressac De Paillerets B" first="Brigitte" last="Bressac-De Paillerets">Brigitte Bressac-De Paillerets</name><affiliation><nlm:affiliation>INSERM U946, Fondation Jean Dausset, Paris, France. Service de Génétique, Institut de Cancérologie Gustave Roussy, Villejuif, France.</nlm:affiliation></affiliation></author><author><name sortKey="Buecher, Bruno" sort="Buecher, Bruno" uniqKey="Buecher B" first="Bruno" last="Buecher">Bruno Buecher</name><affiliation><nlm:affiliation>Institut Curie, Department of Tumour Biology, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Delnatte, Capucine" sort="Delnatte, Capucine" uniqKey="Delnatte C" first="Capucine" last="Delnatte">Capucine Delnatte</name><affiliation><nlm:affiliation>Centre René Gauducheau, Nantes, France.</nlm:affiliation></affiliation></author><author><name sortKey="Houdayer, Claude" sort="Houdayer, Claude" uniqKey="Houdayer C" first="Claude" last="Houdayer">Claude Houdayer</name><affiliation><nlm:affiliation>Institut Curie, Department of Tumour Biology, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, France.</nlm:affiliation></affiliation></author><author><name sortKey="Stoppa Lyonnet, Dominique" sort="Stoppa Lyonnet, Dominique" uniqKey="Stoppa Lyonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name><affiliation><nlm:affiliation>Institut Curie, Department of Tumour Biology, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, France. Institut Curie, INSERM U830, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Damiola, Francesca" sort="Damiola, Francesca" uniqKey="Damiola F" first="Francesca" last="Damiola">Francesca Damiola</name><affiliation><nlm:affiliation>INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Coupier, Isabelle" sort="Coupier, Isabelle" uniqKey="Coupier I" first="Isabelle" last="Coupier">Isabelle Coupier</name><affiliation><nlm:affiliation>Unité d'Oncogénétique, CHU Arnaud de Villeneuve, Montpellier, France. Unité d'Oncogénétique, CRLCC Val d'Aurelle, Montpellier, France.</nlm:affiliation></affiliation></author><author><name sortKey="Barjhoux, Laure" sort="Barjhoux, Laure" uniqKey="Barjhoux L" first="Laure" last="Barjhoux">Laure Barjhoux</name><affiliation><nlm:affiliation>Unité d'Oncogénétique, CRLCC Val d'Aurelle, Montpellier, France.</nlm:affiliation></affiliation></author><author><name sortKey="Venat Bouvet, Laurence" sort="Venat Bouvet, Laurence" uniqKey="Venat Bouvet L" first="Laurence" last="Venat-Bouvet">Laurence Venat-Bouvet</name><affiliation><nlm:affiliation>Department of Medical Oncology, Centre Hospitalier Universitaire Dupuytren, Limoges, France.</nlm:affiliation></affiliation></author><author><name sortKey="Golmard, Lisa" sort="Golmard, Lisa" uniqKey="Golmard L" first="Lisa" last="Golmard">Lisa Golmard</name><affiliation><nlm:affiliation>Institut Curie, Department of Tumour Biology, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Boutry Kryza, Nadia" sort="Boutry Kryza, Nadia" uniqKey="Boutry Kryza N" first="Nadia" last="Boutry-Kryza">Nadia Boutry-Kryza</name><affiliation><nlm:affiliation>Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon - Centre Léon Bérard, Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Sinilnikova, Olga M" sort="Sinilnikova, Olga M" uniqKey="Sinilnikova O" first="Olga M" last="Sinilnikova">Olga M. Sinilnikova</name><affiliation><nlm:affiliation>INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France. Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon - Centre Léon Bérard, Lyon, France. IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Caron, Olivier" sort="Caron, Olivier" uniqKey="Caron O" first="Olivier" last="Caron">Olivier Caron</name><affiliation><nlm:affiliation>Consultation de Génétique, Département de Médecine, Institut de Cancérologie Gustave Roussy, Villejuif, France.</nlm:affiliation></affiliation></author><author><name sortKey="Pujol, Pascal" sort="Pujol, Pascal" uniqKey="Pujol P" first="Pascal" last="Pujol">Pascal Pujol</name><affiliation><nlm:affiliation>Unité d'Oncogénétique, CHU Arnaud de Villeneuve, Montpellier, France. INSERM 896, CRCM Val d'Aurelle, Montpellier, France.</nlm:affiliation></affiliation></author><author><name sortKey="Mazoyer, Sylvie" sort="Mazoyer, Sylvie" uniqKey="Mazoyer S" first="Sylvie" last="Mazoyer">Sylvie Mazoyer</name><affiliation><nlm:affiliation>INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.</nlm:affiliation></affiliation></author><author><name sortKey="Belotti, Muriel" sort="Belotti, Muriel" uniqKey="Belotti M" first="Muriel" last="Belotti">Muriel Belotti</name><affiliation><nlm:affiliation>Institut Curie, Department of Tumour Biology, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Piedmonte, Marion" sort="Piedmonte, Marion" uniqKey="Piedmonte M" first="Marion" last="Piedmonte">Marion Piedmonte</name><affiliation><nlm:affiliation>Gynecologic Oncology Group Statistical and Data Center, Roswell Park Cancer Institute, Buffalo, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Friedlander, Michael L" sort="Friedlander, Michael L" uniqKey="Friedlander M" first="Michael L" last="Friedlander">Michael L. Friedlander</name><affiliation><nlm:affiliation>Australia New Zealand Gynaecological Oncology Group (ANZGOG), Coordinating Centre, Camperdown, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Rodriguez, Gustavo C" sort="Rodriguez, Gustavo C" uniqKey="Rodriguez G" first="Gustavo C" last="Rodriguez">Gustavo C. Rodriguez</name><affiliation><nlm:affiliation>Division of Gynecologic Oncology, NorthShore University HealthSystem, Evanston, Illinois.</nlm:affiliation></affiliation></author><author><name sortKey="Copeland, Larry J" sort="Copeland, Larry J" uniqKey="Copeland L" first="Larry J" last="Copeland">Larry J. Copeland</name><affiliation><nlm:affiliation>Ohio State University, Department of Obstetrics and Gynecology, Hilliard, Ohio.</nlm:affiliation></affiliation></author><author><name sortKey="De La Hoya, Miguel" sort="De La Hoya, Miguel" uniqKey="De La Hoya M" first="Miguel" last="De La Hoya">Miguel De La Hoya</name><affiliation><nlm:affiliation>Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Segura, Pedro Perez" sort="Segura, Pedro Perez" uniqKey="Segura P" first="Pedro Perez" last="Segura">Pedro Perez Segura</name><affiliation><nlm:affiliation>Department of Oncology, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland. University of Helsinki, Helsinki, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland.</nlm:affiliation></affiliation></author><author><name sortKey="Van Os, Theo A M" sort="Van Os, Theo A M" uniqKey="Van Os T" first="Theo A M" last="Van Os">Theo A M. Van Os</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Meijers Heijboer, Hanne E J" sort="Meijers Heijboer, Hanne E J" uniqKey="Meijers Heijboer H" first="Hanne E J" last="Meijers-Heijboer">Hanne E J. Meijers-Heijboer</name><affiliation><nlm:affiliation>Department of Clinical Genetics, VU University Medical Centre, Amsterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Van Der Hout, Annemarie H" sort="Van Der Hout, Annemarie H" uniqKey="Van Der Hout A" first="Annemarie H" last="Van Der Hout">Annemarie H. Van Der Hout</name><affiliation><nlm:affiliation>Department of Genetics, University Medical Center, Groningen University, Groningen, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Vreeswijk, Maaike P G" sort="Vreeswijk, Maaike P G" uniqKey="Vreeswijk M" first="Maaike P G" last="Vreeswijk">Maaike P G. Vreeswijk</name><affiliation><nlm:affiliation>Department of Human Genetics, Leiden University Medical Center (LUMC), Leiden, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Hoogerbrugge, Nicoline" sort="Hoogerbrugge, Nicoline" uniqKey="Hoogerbrugge N" first="Nicoline" last="Hoogerbrugge">Nicoline Hoogerbrugge</name><affiliation><nlm:affiliation>Department of Human Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Ausems, Margreet G E M" sort="Ausems, Margreet G E M" uniqKey="Ausems M" first="Margreet G E M" last="Ausems">Margreet G E M. Ausems</name><affiliation><nlm:affiliation>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Van Doorn, Helena C" sort="Van Doorn, Helena C" uniqKey="Van Doorn H" first="Helena C" last="Van Doorn">Helena C. Van Doorn</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Erasmus University MC Cancer Institute, Rotterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Collee, J Margriet" sort="Collee, J Margriet" uniqKey="Collee J" first="J Margriet" last="Collée">J Margriet Collée</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, the Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Olah, Edith" sort="Olah, Edith" uniqKey="Olah E" first="Edith" last="Olah">Edith Olah</name><affiliation><nlm:affiliation>Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary.</nlm:affiliation></affiliation></author><author><name sortKey="Diez, Orland" sort="Diez, Orland" uniqKey="Diez O" first="Orland" last="Diez">Orland Diez</name><affiliation><nlm:affiliation>Oncogenetics Group, University Hospital Vall d'Hebron, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Blanco, Ignacio" sort="Blanco, Ignacio" uniqKey="Blanco I" first="Ignacio" last="Blanco">Ignacio Blanco</name><affiliation><nlm:affiliation>Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Lazaro, Conxi" sort="Lazaro, Conxi" uniqKey="Lazaro C" first="Conxi" last="Lazaro">Conxi Lazaro</name><affiliation><nlm:affiliation>Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Brunet, Joan" sort="Brunet, Joan" uniqKey="Brunet J" first="Joan" last="Brunet">Joan Brunet</name><affiliation><nlm:affiliation>Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI-Catalan Institute of Oncology, Girona, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Feliubadalo, Lidia" sort="Feliubadalo, Lidia" uniqKey="Feliubadalo L" first="Lidia" last="Feliubadalo">Lidia Feliubadalo</name><affiliation><nlm:affiliation>BMC, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Cybulski, Cezary" sort="Cybulski, Cezary" uniqKey="Cybulski C" first="Cezary" last="Cybulski">Cezary Cybulski</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Jaworska Bieniek, Katarzyna" sort="Jaworska Bieniek, Katarzyna" uniqKey="Jaworska Bieniek K" first="Katarzyna" last="Jaworska-Bieniek">Katarzyna Jaworska-Bieniek</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Sukiennicki, Grzegorz" sort="Sukiennicki, Grzegorz" uniqKey="Sukiennicki G" first="Grzegorz" last="Sukiennicki">Grzegorz Sukiennicki</name><affiliation><nlm:affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</nlm:affiliation></affiliation></author><author><name sortKey="Arason, Adalgeir" sort="Arason, Adalgeir" uniqKey="Arason A" first="Adalgeir" last="Arason">Adalgeir Arason</name><affiliation><nlm:affiliation>BMC, Faculty of Medicine, University of Iceland, Reykjavik, Iceland. Department of Pathology, Landspitali University Hospital, Reykjavik, Iceland.</nlm:affiliation></affiliation></author><author><name sortKey="Chiquette, Jocelyne" sort="Chiquette, Jocelyne" uniqKey="Chiquette J" first="Jocelyne" last="Chiquette">Jocelyne Chiquette</name><affiliation><nlm:affiliation>Unité de Recherche en Santé des Populations, Centre des Maladies du Sein Deschênes-Fabia, Centre de Recherche FRSQ du Centre Hospitalier Affilié Universitaire de Québec, Québec, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Teixeira, Manuel R" sort="Teixeira, Manuel R" uniqKey="Teixeira M" first="Manuel R" last="Teixeira">Manuel R. Teixeira</name><affiliation><nlm:affiliation>Biomedical Sciences Institute (ICBAS), Porto University, Porto, Portugal. Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.</nlm:affiliation></affiliation></author><author><name sortKey="Olswold, Curtis" sort="Olswold, Curtis" uniqKey="Olswold C" first="Curtis" last="Olswold">Curtis Olswold</name><affiliation><nlm:affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnessotta.</nlm:affiliation></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J" last="Couch">Fergus J. Couch</name><affiliation><nlm:affiliation>Department of Laboratory Medicine and Pathology, and Health Sciences Research, Mayo Clinic, Rochester, Minnessotta.</nlm:affiliation></affiliation></author><author><name sortKey="Lindor, Noralane M" sort="Lindor, Noralane M" uniqKey="Lindor N" first="Noralane M" last="Lindor">Noralane M. Lindor</name><affiliation><nlm:affiliation>Health Sciences Research, Mayo Clinic, Scottsdale, Arizona.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation><nlm:affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnessotta.</nlm:affiliation></affiliation></author><author><name sortKey="Szabo, Csilla I" sort="Szabo, Csilla I" uniqKey="Szabo C" first="Csilla I" last="Szabo">Csilla I. Szabo</name><affiliation><nlm:affiliation>National Human Genome Research Institute, NIH, Bethesda, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name><affiliation><nlm:affiliation>Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Corines, Marina" sort="Corines, Marina" uniqKey="Corines M" first="Marina" last="Corines">Marina Corines</name><affiliation><nlm:affiliation>Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Jacobs, Lauren" sort="Jacobs, Lauren" uniqKey="Jacobs L" first="Lauren" last="Jacobs">Lauren Jacobs</name><affiliation><nlm:affiliation>Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Robson, Mark E" sort="Robson, Mark E" uniqKey="Robson M" first="Mark E" last="Robson">Mark E. Robson</name><affiliation><nlm:affiliation>Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Zhang, Liying" sort="Zhang, Liying" uniqKey="Zhang L" first="Liying" last="Zhang">Liying Zhang</name><affiliation><nlm:affiliation>Diagnostic Molecular Genetics Laboratory, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Joseph, Vijai" sort="Joseph, Vijai" uniqKey="Joseph V" first="Vijai" last="Joseph">Vijai Joseph</name><affiliation><nlm:affiliation>Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York.</nlm:affiliation></affiliation></author><author><name sortKey="Berger, Andreas" sort="Berger, Andreas" uniqKey="Berger A" first="Andreas" last="Berger">Andreas Berger</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Singer, Christian F" sort="Singer, Christian F" uniqKey="Singer C" first="Christian F" last="Singer">Christian F. Singer</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Rappaport, Christine" sort="Rappaport, Christine" uniqKey="Rappaport C" first="Christine" last="Rappaport">Christine Rappaport</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Kaulich, Daphne Geschwantler" sort="Kaulich, Daphne Geschwantler" uniqKey="Kaulich D" first="Daphne Geschwantler" last="Kaulich">Daphne Geschwantler Kaulich</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Pfeiler, Georg" sort="Pfeiler, Georg" uniqKey="Pfeiler G" first="Georg" last="Pfeiler">Georg Pfeiler</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Tea, Muy Kheng M" sort="Tea, Muy Kheng M" uniqKey="Tea M" first="Muy-Kheng M" last="Tea">Muy-Kheng M. Tea</name><affiliation><nlm:affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Phelan, Catherine M" sort="Phelan, Catherine M" uniqKey="Phelan C" first="Catherine M" last="Phelan">Catherine M. Phelan</name><affiliation><nlm:affiliation>Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida.</nlm:affiliation></affiliation></author><author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H" last="Greene">Mark H. Greene</name><affiliation><nlm:affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Mai, Phuong L" sort="Mai, Phuong L" uniqKey="Mai P" first="Phuong L" last="Mai">Phuong L. Mai</name><affiliation><nlm:affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, Maryland.</nlm:affiliation></affiliation></author><author><name sortKey="Rennert, Gad" sort="Rennert, Gad" uniqKey="Rennert G" first="Gad" last="Rennert">Gad Rennert</name><affiliation><nlm:affiliation>Clalit National Cancer Control Center, Haifa, Israel.</nlm:affiliation></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation><nlm:affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation><nlm:affiliation>Ontario Cancer Genetics Network: Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Tchatchou, Sandrine" sort="Tchatchou, Sandrine" uniqKey="Tchatchou S" first="Sandrine" last="Tchatchou">Sandrine Tchatchou</name><affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name><affiliation><nlm:affiliation>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada.</nlm:affiliation></affiliation></author><author><name sortKey="Toland, Amanda Ewart" sort="Toland, Amanda Ewart" uniqKey="Toland A" first="Amanda Ewart" last="Toland">Amanda Ewart Toland</name><affiliation><nlm:affiliation>Division of Human Cancer Genetics, Departments of Internal Medicine and Molecular Virology, Immunology, and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.</nlm:affiliation></affiliation></author><author><name sortKey="Bojesen, Anders" sort="Bojesen, Anders" uniqKey="Bojesen A" first="Anders" last="Bojesen">Anders Bojesen</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Pedersen, Inge Sokilde" sort="Pedersen, Inge Sokilde" uniqKey="Pedersen I" first="Inge Sokilde" last="Pedersen">Inge Sokilde Pedersen</name><affiliation><nlm:affiliation>Section of Molecular Diagnostics, Department of Biochemistry, Aalborg University Hospital, Aalborg, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Thomassen, Mads" sort="Thomassen, Mads" uniqKey="Thomassen M" first="Mads" last="Thomassen">Mads Thomassen</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Jensen, Uffe Birk" sort="Jensen, Uffe Birk" uniqKey="Jensen U" first="Uffe Birk" last="Jensen">Uffe Birk Jensen</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.</nlm:affiliation></affiliation></author><author><name sortKey="Laitman, Yael" sort="Laitman, Yael" uniqKey="Laitman Y" first="Yael" last="Laitman">Yael Laitman</name><affiliation><nlm:affiliation>Sheba Medical Center, Tel Aviv, Israel.</nlm:affiliation></affiliation></author><author><name sortKey="Rantala, Johanna" sort="Rantala, Johanna" uniqKey="Rantala J" first="Johanna" last="Rantala">Johanna Rantala</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Von Wachenfeldt, Anna" sort="Von Wachenfeldt, Anna" uniqKey="Von Wachenfeldt A" first="Anna" last="Von Wachenfeldt">Anna Von Wachenfeldt</name><affiliation><nlm:affiliation>Department of Oncology, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Ehrencrona, Hans" sort="Ehrencrona, Hans" uniqKey="Ehrencrona H" first="Hans" last="Ehrencrona">Hans Ehrencrona</name><affiliation><nlm:affiliation>Department of Clinical Genetics, Lund University Hospital, Lund, Sweden. Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Askmalm, Marie Stenmark" sort="Askmalm, Marie Stenmark" uniqKey="Askmalm M" first="Marie Stenmark" last="Askmalm">Marie Stenmark Askmalm</name><affiliation><nlm:affiliation>Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Borg, Ke" sort="Borg, Ke" uniqKey="Borg " first=" Ke" last="Borg"> Ke Borg</name><affiliation><nlm:affiliation>Department of Oncology, Lund University, Lund, Sweden.</nlm:affiliation></affiliation></author><author><name sortKey="Kuchenbaecker, Karoline B" sort="Kuchenbaecker, Karoline B" uniqKey="Kuchenbaecker K" first="Karoline B" last="Kuchenbaecker">Karoline B. Kuchenbaecker</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Mcguffog, Lesley" sort="Mcguffog, Lesley" uniqKey="Mcguffog L" first="Lesley" last="Mcguffog">Lesley Mcguffog</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Barrowdale, Daniel" sort="Barrowdale, Daniel" uniqKey="Barrowdale D" first="Daniel" last="Barrowdale">Daniel Barrowdale</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Healey, Sue" sort="Healey, Sue" uniqKey="Healey S" first="Sue" last="Healey">Sue Healey</name><affiliation><nlm:affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Lee, Andrew" sort="Lee, Andrew" uniqKey="Lee A" first="Andrew" last="Lee">Andrew Lee</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D P" last="Pharoah">Paul D P. Pharoah</name><affiliation><nlm:affiliation>Department of Oncology, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation><nlm:affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C" last="Antoniou">Antonis C. Antoniou</name><affiliation><nlm:affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</nlm:affiliation></affiliation></author><author><name sortKey="Friedman, Eitan" sort="Friedman, Eitan" uniqKey="Friedman E" first="Eitan" last="Friedman">Eitan Friedman</name><affiliation><nlm:affiliation>Sheba Medical Center, Tel Aviv, Israel. paolo.peterlongo@ifom.eu eitan.friedman@sheba.health.gov.il feitan@post.tau.ac.il.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology</title><idno type="eISSN">1538-7755</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Breast Neoplasms (genetics)</term><term>Cohort Studies</term><term>Female</term><term>Genes, BRCA1 (physiology)</term><term>Genes, BRCA2 (physiology)</term><term>Humans</term><term>Mutation</term><term>Ovarian Neoplasms (genetics)</term><term>Polymorphism, Single Nucleotide</term><term>Retrospective Studies</term><term>Young Adult</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Breast Neoplasms</term><term>Ovarian Neoplasms</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Genes, BRCA1</term><term>Genes, BRCA2</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Cohort Studies</term><term>Female</term><term>Humans</term><term>Mutation</term><term>Polymorphism, Single Nucleotide</term><term>Retrospective Studies</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">BRCA1 and BRCA2 mutation carriers are at substantially increased risk for developing breast and ovarian cancer. The incomplete penetrance coupled with the variable age at diagnosis in carriers of the same mutation suggests the existence of genetic and nongenetic modifying factors. In this study, we evaluated the putative role of variants in many candidate modifier genes.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25336561</PMID><DateCreated><Year>2015</Year><Month>01</Month><Day>14</Day></DateCreated><DateCompleted><Year>2015</Year><Month>09</Month><Day>18</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>22</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1538-7755</ISSN><JournalIssue CitedMedium="Internet"><Volume>24</Volume><Issue>1</Issue><PubDate><Year>2015</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology</Title><ISOAbbreviation>Cancer Epidemiol. Biomarkers Prev.</ISOAbbreviation></Journal><ArticleTitle>Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.</ArticleTitle><Pagination><MedlinePgn>308-16</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1158/1055-9965.EPI-14-0532</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">BRCA1 and BRCA2 mutation carriers are at substantially increased risk for developing breast and ovarian cancer. The incomplete penetrance coupled with the variable age at diagnosis in carriers of the same mutation suggests the existence of genetic and nongenetic modifying factors. In this study, we evaluated the putative role of variants in many candidate modifier genes.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Genotyping data from 15,252 BRCA1 and 8,211 BRCA2 mutation carriers, for known variants (n = 3,248) located within or around 445 candidate genes, were available through the iCOGS custom-designed array. Breast and ovarian cancer association analysis was performed within a retrospective cohort approach.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The observed P values of association ranged between 0.005 and 1.000. None of the variants was significantly associated with breast or ovarian cancer risk in either BRCA1 or BRCA2 mutation carriers, after multiple testing adjustments.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">There is little evidence that any of the evaluated candidate variants act as modifiers of breast and/or ovarian cancer risk in BRCA1 or BRCA2 mutation carriers.</AbstractText><AbstractText Label="IMPACT" NlmCategory="CONCLUSIONS">Genome-wide association studies have been more successful at identifying genetic modifiers of BRCA1/2 penetrance than candidate gene studies.</AbstractText><CopyrightInformation>©2014 American Association for Cancer Research.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Peterlongo</LastName><ForeName>Paolo</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy. paolo.peterlongo@ifom.eu eitan.friedman@sheba.health.gov.il feitan@post.tau.ac.il.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chang-Claude</LastName><ForeName>Jenny</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moysich</LastName><ForeName>Kirsten B</ForeName><Initials>KB</Initials><AffiliationInfo><Affiliation>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rudolph</LastName><ForeName>Anja</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmutzler</LastName><ForeName>Rita K</ForeName><Initials>RK</Initials><AffiliationInfo><Affiliation>Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne, Germany. Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Germany. Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany, on behalf of the German Consortium of Hereditary Breast and Ovarian Cancer (GC-HBOC).</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Simard</LastName><ForeName>Jacques</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Soucy</LastName><ForeName>Penny</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eeles</LastName><ForeName>Rosalind A</ForeName><Initials>RA</Initials><AffiliationInfo><Affiliation>Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Surrey, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Easton</LastName><ForeName>Douglas F</ForeName><Initials>DF</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hamann</LastName><ForeName>Ute</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wilkening</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Genomic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Bowang</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rookus</LastName><ForeName>Matti A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Marjanka K</ForeName><Initials>MK</Initials><AffiliationInfo><Affiliation>Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Baan</LastName><ForeName>Frederieke H</ForeName><Initials>FH</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Spurdle</LastName><ForeName>Amanda B</ForeName><Initials>AB</Initials><AffiliationInfo><Affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Walker</LastName><ForeName>Logan C</ForeName><Initials>LC</Initials><AffiliationInfo><Affiliation>Department of Pathology, University of Otago, Christchurch, New Zealand.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lose</LastName><ForeName>Felicity</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maia</LastName><ForeName>Ana-Teresa</ForeName><Initials>AT</Initials><AffiliationInfo><Affiliation>Department of Biomedical Sciences and Medicine, Gambelas Campus, University of Algarve, Portugal.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Montagna</LastName><ForeName>Marco</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV - IRCCS, Padua, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Matricardi</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV - IRCCS, Padua, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lubinski</LastName><ForeName>Jan</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jakubowska</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gómez Garcia</LastName><ForeName>Encarna B</ForeName><Initials>EB</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, MUMC, Maastricht, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Olopade</LastName><ForeName>Olufunmilayo I</ForeName><Initials>OI</Initials><AffiliationInfo><Affiliation>Center for Clinical Cancer Genetics, Department of Medicine and Human Genetics, University of Chicago Medical Center, Chicago, Illinois.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nussbaum</LastName><ForeName>Robert L</ForeName><Initials>RL</Initials><AffiliationInfo><Affiliation>Department of Medicine and Institute for Human Genetics, University of California, San Francisco, San Francisco, California.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nathanson</LastName><ForeName>Katherine L</ForeName><Initials>KL</Initials><AffiliationInfo><Affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadephia, Pennsylvania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Domchek</LastName><ForeName>Susan M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadephia, Pennsylvania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rebbeck</LastName><ForeName>Timothy R</ForeName><Initials>TR</Initials><AffiliationInfo><Affiliation>Department of Epidemiology and Biostatistics, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadephia, Pennsylvania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arun</LastName><ForeName>Banu K</ForeName><Initials>BK</Initials><AffiliationInfo><Affiliation>University of Texas MD Anderson Cancer Center, Houston, Texas.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karlan</LastName><ForeName>Beth Y</ForeName><Initials>BY</Initials><AffiliationInfo><Affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Orsulic</LastName><ForeName>Sandra</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lester</LastName><ForeName>Jenny</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chung</LastName><ForeName>Wendy K</ForeName><Initials>WK</Initials><AffiliationInfo><Affiliation>Departments of Pediatrics and Medicine, Columbia University, New York, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Miron</LastName><ForeName>Alex</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Genetics and Genomics at Case Western Reserve Medical School, Cleveland, Ohio.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Southey</LastName><ForeName>Melissa C</ForeName><Initials>MC</Initials><AffiliationInfo><Affiliation>Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Goldgar</LastName><ForeName>David E</ForeName><Initials>DE</Initials><AffiliationInfo><Affiliation>Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buys</LastName><ForeName>Saundra S</ForeName><Initials>SS</Initials><AffiliationInfo><Affiliation>Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Janavicius</LastName><ForeName>Ramunas</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Vilnius University Hospital Santariskiu Clinics, Hematology, Oncology, and Transfusion Medicine Center, Dept. of Molecular and Regenerative Medicine; State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dorfling</LastName><ForeName>Cecilia M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>Department of Genetics, University of Pretoria, Pretoria, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Rensburg</LastName><ForeName>Elizabeth J</ForeName><Initials>EJ</Initials><AffiliationInfo><Affiliation>Department of Genetics, University of Pretoria, Pretoria, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ding</LastName><ForeName>Yuan Chun</ForeName><Initials>YC</Initials><AffiliationInfo><Affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Neuhausen</LastName><ForeName>Susan L</ForeName><Initials>SL</Initials><AffiliationInfo><Affiliation>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hansen</LastName><ForeName>Thomas V O</ForeName><Initials>TV</Initials><AffiliationInfo><Affiliation>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gerdes</LastName><ForeName>Anne-Marie</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ejlertsen</LastName><ForeName>Bent</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jønson</LastName><ForeName>Lars</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Osorio</LastName><ForeName>Ana</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Martínez-Bouzas</LastName><ForeName>Cristina</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Molecular Genetics Laboratory, Department of Biochemistry, Cruces Hospital Barakaldo, 48903-Barakaldo-Bizkaia, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Benitez</LastName><ForeName>Javier</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. Human Genetics Group and Genotyping Unit, Spanish National Cancer Centre (CNIO), Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Conway</LastName><ForeName>Edye E</ForeName><Initials>EE</Initials><AffiliationInfo><Affiliation>Saint Alphonsus Regional Medical Center, care of City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Blazer</LastName><ForeName>Kathleen R</ForeName><Initials>KR</Initials><AffiliationInfo><Affiliation>Clinical Cancer Genetics, City of Hope, Duarte, California.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Weitzel</LastName><ForeName>Jeffrey N</ForeName><Initials>JN</Initials><AffiliationInfo><Affiliation>Clinical Cancer Genetics, City of Hope, Duarte, California (for the City of Hope Clinical Cancer Genetics Community Research Network).</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Manoukian</LastName><ForeName>Siranoush</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peissel</LastName><ForeName>Bernard</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zaffaroni</LastName><ForeName>Daniela</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scuvera</LastName><ForeName>Giulietta</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barile</LastName><ForeName>Monica</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ficarazzi</LastName><ForeName>Filomena</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Cogentech Cancer Genetic Test Laboratory, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mariette</LastName><ForeName>Frederique</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Cogentech Cancer Genetic Test Laboratory, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fortuzzi</LastName><ForeName>Stefano</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. Cogentech Cancer Genetic Test Laboratory, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Viel</LastName><ForeName>Alessandra</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Division of Experimental Oncology 1, CRO Aviano National Cancer Institute, Aviano (PN), Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Giannini</LastName><ForeName>Giuseppe</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Molecular Medicine, Sapienza University, Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Papi</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Unit of Medical Genetics, Department of Biomedical, Experimental, and Clinical Sciences, University of Florence, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Martayan</LastName><ForeName>Aline</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Unit of Genetic Counseling, Medical Oncology Department, Istituto Nazionale Tumori Regina Elena, Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tibiletti</LastName><ForeName>Maria Grazia</ForeName><Initials>MG</Initials><AffiliationInfo><Affiliation>UO Anatomia Patologica Ospedale di Circolo e Fondazione Macchi, Polo Universitario Varese, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Radice</LastName><ForeName>Paolo</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vratimos</LastName><ForeName>Athanassios</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens, Greece.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fostira</LastName><ForeName>Florentia</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research "Demokritos", Aghia Paraskevi Attikis, Athens, Greece.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Garber</LastName><ForeName>Judy E</ForeName><Initials>JE</Initials><AffiliationInfo><Affiliation>Dana-Farber Cancer Institute, Boston, Massachuestts.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Donaldson</LastName><ForeName>Alan</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Clinical Genetics Department, St. Michael's Hospital, Bristol, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brewer</LastName><ForeName>Carole</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Royal Devon & Exeter Hospital, Exeter, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Foo</LastName><ForeName>Claire</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Cheshire & Merseyside Clinical Genetics Service, Liverpool Women's NHS Foundation Trust, Liverpool, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Evans</LastName><ForeName>D Gareth R</ForeName><Initials>DG</Initials><AffiliationInfo><Affiliation>Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Frost</LastName><ForeName>Debra</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eccles</LastName><ForeName>Diana</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>University of Southampton, Faculty of Medicine, Southampton University Hospitals NHS Trust, Southampton, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brady</LastName><ForeName>Angela</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>North West Thames Regional Genetics Service, Kennedy-Galton Centre, Harrow, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cook</LastName><ForeName>Jackie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tischkowitz</LastName><ForeName>Marc</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, East Anglian Regional Genetics Service, Addenbrookes Hospital, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Adlard</LastName><ForeName>Julian</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Yorkshire Regional Genetics Service, Leeds, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barwell</LastName><ForeName>Julian</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Leicestershire Clinical Genetics Service, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Walker</LastName><ForeName>Lisa</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Oxford Regional Genetics Service, Churchill Hospital, Oxford, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Izatt</LastName><ForeName>Louise</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Side</LastName><ForeName>Lucy E</ForeName><Initials>LE</Initials><AffiliationInfo><Affiliation>North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kennedy</LastName><ForeName>M John</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>Academic Unit of Clinical and Molecular Oncology, Trinity College Dublin, Ireland. St. James's Hospital, Dublin, Ireland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rogers</LastName><ForeName>Mark T</ForeName><Initials>MT</Initials><AffiliationInfo><Affiliation>All Wales Medical Genetics Services, University Hospital of Wales, Cardiff, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Porteous</LastName><ForeName>Mary E</ForeName><Initials>ME</Initials><AffiliationInfo><Affiliation>South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Morrison</LastName><ForeName>Patrick J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Centre for Cancer Research and Cell Biology, Queens University of Belfast, Department of Medical Genetics, Belfast HSC Trust, Belfast, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Platte</LastName><ForeName>Radka</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Davidson</LastName><ForeName>Rosemarie</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>West of Scotland Regional Genetics Service, Southern General Hospital, Glasgow, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hodgson</LastName><ForeName>Shirley V</ForeName><Initials>SV</Initials><AffiliationInfo><Affiliation>Medical Genetics Unit, St. George's, University of London, London, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ellis</LastName><ForeName>Steve</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cole</LastName><ForeName>Trevor</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>EMBRACE</CollectiveName></Author><Author ValidYN="Y"><LastName>Godwin</LastName><ForeName>Andrew K</ForeName><Initials>AK</Initials><AffiliationInfo><Affiliation>Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Missouri.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Claes</LastName><ForeName>Kathleen</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Van Maerken</LastName><ForeName>Tom</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Center for Medical Genetics, Ghent University, Ghent, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meindl</LastName><ForeName>Alfons</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gehrig</LastName><ForeName>Andrea</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute of Human Genetics, University Würzburg, Wurzburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sutter</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>University Heidelberg, Heidelberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Engel</LastName><ForeName>Christoph</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Institute for Medical Informatics, Statistics, and Epidemiology, University of Leipzig, Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Niederacher</LastName><ForeName>Dieter</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>University Düsseldorf, Dusseldorf, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Steinemann</LastName><ForeName>Doris</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Hannover Medical School, Hanover, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Plendl</LastName><ForeName>Hansjoerg</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Institute of Human Genetics, University Hospital of Schleswig-Holstein/University Kiel, Kiel, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kast</LastName><ForeName>Karin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rhiem</LastName><ForeName>Kerstin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne, Germany. Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Germany. Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ditsch</LastName><ForeName>Nina</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, University Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arnold</LastName><ForeName>Norbert</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Gynecology and Obstetrics, University Hospital of Schleswig-Holstein/University Kiel, Kiel, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Varon-Mateeva</LastName><ForeName>Raymonda</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Institute of Human Genetics, Charite Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wappenschmidt</LastName><ForeName>Barbara</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne, Germany. Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Germany. Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang-Gohrke</LastName><ForeName>Shan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Gynaecology and Obstetrics, University Hospital Ulm, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bressac-de Paillerets</LastName><ForeName>Brigitte</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>INSERM U946, Fondation Jean Dausset, Paris, France. Service de Génétique, Institut de Cancérologie Gustave Roussy, Villejuif, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Buecher</LastName><ForeName>Bruno</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Institut Curie, Department of Tumour Biology, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Delnatte</LastName><ForeName>Capucine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Centre René Gauducheau, Nantes, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Houdayer</LastName><ForeName>Claude</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Institut Curie, Department of Tumour Biology, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stoppa-Lyonnet</LastName><ForeName>Dominique</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Institut Curie, Department of Tumour Biology, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, France. Institut Curie, INSERM U830, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Damiola</LastName><ForeName>Francesca</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Coupier</LastName><ForeName>Isabelle</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Unité d'Oncogénétique, CHU Arnaud de Villeneuve, Montpellier, France. Unité d'Oncogénétique, CRLCC Val d'Aurelle, Montpellier, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barjhoux</LastName><ForeName>Laure</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Unité d'Oncogénétique, CRLCC Val d'Aurelle, Montpellier, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Venat-Bouvet</LastName><ForeName>Laurence</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Medical Oncology, Centre Hospitalier Universitaire Dupuytren, Limoges, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Golmard</LastName><ForeName>Lisa</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Institut Curie, Department of Tumour Biology, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boutry-Kryza</LastName><ForeName>Nadia</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon - Centre Léon Bérard, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sinilnikova</LastName><ForeName>Olga M</ForeName><Initials>OM</Initials><AffiliationInfo><Affiliation>INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France. Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon - Centre Léon Bérard, Lyon, France. IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Caron</LastName><ForeName>Olivier</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Consultation de Génétique, Département de Médecine, Institut de Cancérologie Gustave Roussy, Villejuif, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pujol</LastName><ForeName>Pascal</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Unité d'Oncogénétique, CHU Arnaud de Villeneuve, Montpellier, France. INSERM 896, CRCM Val d'Aurelle, Montpellier, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mazoyer</LastName><ForeName>Sylvie</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Belotti</LastName><ForeName>Muriel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institut Curie, Department of Tumour Biology, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>GEMO Study Collaborators</CollectiveName></Author><Author ValidYN="Y"><LastName>Piedmonte</LastName><ForeName>Marion</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Gynecologic Oncology Group Statistical and Data Center, Roswell Park Cancer Institute, Buffalo, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Friedlander</LastName><ForeName>Michael L</ForeName><Initials>ML</Initials><AffiliationInfo><Affiliation>Australia New Zealand Gynaecological Oncology Group (ANZGOG), Coordinating Centre, Camperdown, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rodriguez</LastName><ForeName>Gustavo C</ForeName><Initials>GC</Initials><AffiliationInfo><Affiliation>Division of Gynecologic Oncology, NorthShore University HealthSystem, Evanston, Illinois.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Copeland</LastName><ForeName>Larry J</ForeName><Initials>LJ</Initials><AffiliationInfo><Affiliation>Ohio State University, Department of Obstetrics and Gynecology, Hilliard, Ohio.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de la Hoya</LastName><ForeName>Miguel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Segura</LastName><ForeName>Pedro Perez</ForeName><Initials>PP</Initials><AffiliationInfo><Affiliation>Department of Oncology, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nevanlinna</LastName><ForeName>Heli</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland. University of Helsinki, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aittomäki</LastName><ForeName>Kristiina</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Os</LastName><ForeName>Theo A M</ForeName><Initials>TA</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meijers-Heijboer</LastName><ForeName>Hanne E J</ForeName><Initials>HE</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, VU University Medical Centre, Amsterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Hout</LastName><ForeName>Annemarie H</ForeName><Initials>AH</Initials><AffiliationInfo><Affiliation>Department of Genetics, University Medical Center, Groningen University, Groningen, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vreeswijk</LastName><ForeName>Maaike P G</ForeName><Initials>MP</Initials><AffiliationInfo><Affiliation>Department of Human Genetics, Leiden University Medical Center (LUMC), Leiden, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hoogerbrugge</LastName><ForeName>Nicoline</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Human Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ausems</LastName><ForeName>Margreet G E M</ForeName><Initials>MG</Initials><AffiliationInfo><Affiliation>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van Doorn</LastName><ForeName>Helena C</ForeName><Initials>HC</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Erasmus University MC Cancer Institute, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Collée</LastName><ForeName>J Margriet</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>HEBON</CollectiveName></Author><Author ValidYN="Y"><LastName>Olah</LastName><ForeName>Edith</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Diez</LastName><ForeName>Orland</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Oncogenetics Group, University Hospital Vall d'Hebron, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Blanco</LastName><ForeName>Ignacio</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lazaro</LastName><ForeName>Conxi</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brunet</LastName><ForeName>Joan</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI-Catalan Institute of Oncology, Girona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Feliubadalo</LastName><ForeName>Lidia</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>BMC, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cybulski</LastName><ForeName>Cezary</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gronwald</LastName><ForeName>Jacek</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Durda</LastName><ForeName>Katarzyna</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jaworska-Bieniek</LastName><ForeName>Katarzyna</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sukiennicki</LastName><ForeName>Grzegorz</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arason</LastName><ForeName>Adalgeir</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>BMC, Faculty of Medicine, University of Iceland, Reykjavik, Iceland. Department of Pathology, Landspitali University Hospital, Reykjavik, Iceland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chiquette</LastName><ForeName>Jocelyne</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Unité de Recherche en Santé des Populations, Centre des Maladies du Sein Deschênes-Fabia, Centre de Recherche FRSQ du Centre Hospitalier Affilié Universitaire de Québec, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Teixeira</LastName><ForeName>Manuel R</ForeName><Initials>MR</Initials><AffiliationInfo><Affiliation>Biomedical Sciences Institute (ICBAS), Porto University, Porto, Portugal. Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Olswold</LastName><ForeName>Curtis</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnessotta.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Couch</LastName><ForeName>Fergus J</ForeName><Initials>FJ</Initials><AffiliationInfo><Affiliation>Department of Laboratory Medicine and Pathology, and Health Sciences Research, Mayo Clinic, Rochester, Minnessotta.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lindor</LastName><ForeName>Noralane M</ForeName><Initials>NM</Initials><AffiliationInfo><Affiliation>Health Sciences Research, Mayo Clinic, Scottsdale, Arizona.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Xianshu</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnessotta.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Szabo</LastName><ForeName>Csilla I</ForeName><Initials>CI</Initials><AffiliationInfo><Affiliation>National Human Genome Research Institute, NIH, Bethesda, Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Offit</LastName><ForeName>Kenneth</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Corines</LastName><ForeName>Marina</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jacobs</LastName><ForeName>Lauren</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Robson</LastName><ForeName>Mark E</ForeName><Initials>ME</Initials><AffiliationInfo><Affiliation>Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Liying</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Diagnostic Molecular Genetics Laboratory, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Joseph</LastName><ForeName>Vijai</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Berger</LastName><ForeName>Andreas</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Singer</LastName><ForeName>Christian F</ForeName><Initials>CF</Initials><AffiliationInfo><Affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rappaport</LastName><ForeName>Christine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaulich</LastName><ForeName>Daphne Geschwantler</ForeName><Initials>DG</Initials><AffiliationInfo><Affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pfeiler</LastName><ForeName>Georg</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tea</LastName><ForeName>Muy-Kheng M</ForeName><Initials>MK</Initials><AffiliationInfo><Affiliation>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Phelan</LastName><ForeName>Catherine M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Greene</LastName><ForeName>Mark H</ForeName><Initials>MH</Initials><AffiliationInfo><Affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mai</LastName><ForeName>Phuong L</ForeName><Initials>PL</Initials><AffiliationInfo><Affiliation>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rennert</LastName><ForeName>Gad</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Clalit National Cancer Control Center, Haifa, Israel.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mulligan</LastName><ForeName>Anna Marie</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Glendon</LastName><ForeName>Gord</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Ontario Cancer Genetics Network: Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tchatchou</LastName><ForeName>Sandrine</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Andrulis</LastName><ForeName>Irene L</ForeName><Initials>IL</Initials><AffiliationInfo><Affiliation>Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Toland</LastName><ForeName>Amanda Ewart</ForeName><Initials>AE</Initials><AffiliationInfo><Affiliation>Division of Human Cancer Genetics, Departments of Internal Medicine and Molecular Virology, Immunology, and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bojesen</LastName><ForeName>Anders</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pedersen</LastName><ForeName>Inge Sokilde</ForeName><Initials>IS</Initials><AffiliationInfo><Affiliation>Section of Molecular Diagnostics, Department of Biochemistry, Aalborg University Hospital, Aalborg, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thomassen</LastName><ForeName>Mads</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jensen</LastName><ForeName>Uffe Birk</ForeName><Initials>UB</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Laitman</LastName><ForeName>Yael</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Sheba Medical Center, Tel Aviv, Israel.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rantala</LastName><ForeName>Johanna</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>von Wachenfeldt</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Oncology, Karolinska University Hospital, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ehrencrona</LastName><ForeName>Hans</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Clinical Genetics, Lund University Hospital, Lund, Sweden. Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Askmalm</LastName><ForeName>Marie Stenmark</ForeName><Initials>MS</Initials><AffiliationInfo><Affiliation>Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Borg</LastName><ForeName>Åke</ForeName><Initials>Å</Initials><AffiliationInfo><Affiliation>Department of Oncology, Lund University, Lund, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kuchenbaecker</LastName><ForeName>Karoline B</ForeName><Initials>KB</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McGuffog</LastName><ForeName>Lesley</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barrowdale</LastName><ForeName>Daniel</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Healey</LastName><ForeName>Sue</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pharoah</LastName><ForeName>Paul D P</ForeName><Initials>PD</Initials><AffiliationInfo><Affiliation>Department of Oncology, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chenevix-Trench</LastName><ForeName>Georgia</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>KConFab Investigators</CollectiveName></Author><Author ValidYN="Y"><LastName>Antoniou</LastName><ForeName>Antonis C</ForeName><Initials>AC</Initials><AffiliationInfo><Affiliation>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Friedman</LastName><ForeName>Eitan</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Sheba Medical Center, Tel Aviv, Israel. paolo.peterlongo@ifom.eu eitan.friedman@sheba.health.gov.il feitan@post.tau.ac.il.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>UL1 TR000430</GrantID><Acronym>TR</Acronym><Agency>NCATS NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>A15007</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>CA116201</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>UG1 CA189867</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>A8385</GrantID><Agency>Cancer Research UK</Agency><Country>United 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States</Country></Grant><Grant><GrantID>C5047/A8384</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>C12292/A11174</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 CA128978</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 CA083855</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><Agency>Canadian Institutes of Health Research</Agency><Country>Canada</Country></Grant><Grant><GrantID>U19 CA148537</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>P50 CA116201</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U01 CA113916</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U10 CA037517</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C1287/A 10710</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>P30 CA015083</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01-CA083855</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>N02CP65504</GrantID><Acronym>CP</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>5U01CA113916</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 CA102776</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C5047/A8385</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>A17523</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>M01 RR000043</GrantID><Acronym>RR</Acronym><Agency>NCRR NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>1U19 CA148112</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>1U19CA148537</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C1281/A12014</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>U19 CA148112</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 CA149429</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U19 CA148065</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>10119</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>C1287/A10118</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>U10 CA180867</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>A16563</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>10118</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>A10710</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>U10 CA180822</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 CA126841</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>C5047/A15007</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>10124</GrantID><Agency>Cancer Research UK</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>N02CP11019</GrantID><Acronym>CP</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013486">Research Support, U.S. Gov't, Non-P.H.S.</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>10</Month><Day>21</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Cancer Epidemiol Biomarkers Prev</MedlineTA><NlmUniqueID>9200608</NlmUniqueID><ISSNLinking>1055-9965</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Am J Hum Genet. 2007 Dec;81(6):1186-200</RefSource><PMID Version="1">17999359</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>JAMA. 2008 Jan 9;299(2):194-201</RefSource><PMID Version="1">18182601</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2010 Oct;42(10):885-92</RefSource><PMID Version="1">20852631</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genet Epidemiol. 2012 Apr;36(3):274-91</RefSource><PMID Version="1">22714938</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Genet. 2013;9(3):e1003173</RefSource><PMID Version="1">23544012</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Hum Mol Genet. 2013 Dec 15;22(24):5056-64</RefSource><PMID Version="1">23900074</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Br J Cancer. 2007 Jan 15;96(1):11-5</RefSource><PMID Version="1">17213823</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Breast Cancer Res. 2007;9(2):104</RefSource><PMID Version="1">17466083</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001943" MajorTopicYN="N">Breast Neoplasms</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019398" MajorTopicYN="N">Genes, BRCA1</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D024522" MajorTopicYN="N">Genes, BRCA2</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009154" MajorTopicYN="N">Mutation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010051" MajorTopicYN="N">Ovarian Neoplasms</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020641" MajorTopicYN="N">Polymorphism, Single Nucleotide</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><OtherID 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