Lung function, airway inflammation, and polycyclic aromatic hydrocarbons exposure in mexican schoolchildren: a pilot study.
Identifieur interne : 003419 ( PubMed/Checkpoint ); précédent : 003418; suivant : 003420Lung function, airway inflammation, and polycyclic aromatic hydrocarbons exposure in mexican schoolchildren: a pilot study.
Auteurs : Albino Barraza-Villarreal [France] ; Maria Consuelo Escamilla-Nu Ez ; Astrid Schilmann ; Leticia Hernandez-Cadena ; Zheng Li ; Lovisa Romanoff ; Andreas Sjödin ; Blanca Estela Del Río-Navarro ; David Díaz-Sanchez ; Fernando Díaz-Barriga ; Peter Sly ; Isabelle RomieuSource :
- Journal of occupational and environmental medicine [ 1536-5948 ] ; 2014.
Descripteurs français
- KwdFr :
- Adolescent, Enfant, Enquêtes et questionnaires, Exposition environnementale (effets indésirables), Facteurs de risque, Femelle, Humains, Hydrocarbures aromatiques polycycliques (toxicité), Hydrocarbures aromatiques polycycliques (urine), Marqueurs biologiques (urine), Mexique (épidémiologie), Mâle, Projets pilotes, Tests de la fonction respiratoire, Études transversales.
- MESH :
- effets indésirables : Exposition environnementale.
- toxicité : Hydrocarbures aromatiques polycycliques.
- urine : Hydrocarbures aromatiques polycycliques, Marqueurs biologiques.
- épidémiologie : Mexique.
- Adolescent, Enfant, Enquêtes et questionnaires, Facteurs de risque, Femelle, Humains, Mâle, Projets pilotes, Tests de la fonction respiratoire, Études transversales.
English descriptors
- KwdEn :
- Adolescent, Biomarkers (urine), Child, Cross-Sectional Studies, Environmental Exposure (adverse effects), Female, Humans, Male, Mexico (epidemiology), Pilot Projects, Polycyclic Aromatic Hydrocarbons (toxicity), Polycyclic Aromatic Hydrocarbons (urine), Respiratory Function Tests, Risk Factors, Surveys and Questionnaires.
- MESH :
- chemical , toxicity : Polycyclic Aromatic Hydrocarbons.
- chemical , urine : Biomarkers, Polycyclic Aromatic Hydrocarbons.
- adverse effects : Environmental Exposure.
- epidemiology : Mexico.
- Adolescent, Child, Cross-Sectional Studies, Female, Humans, Male, Pilot Projects, Respiratory Function Tests, Risk Factors, Surveys and Questionnaires.
Abstract
To determine the association of exposure to polycyclic aromatic hydrocarbons (PAHs) with lung function and pH of exhaled breath condensate (EBC) in Mexican schoolchildren.
DOI: 10.1097/JOM.0000000000000111
PubMed: 24500378
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:24500378Le document en format XML
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<term>Biomarkers (urine)</term>
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<term>Environmental Exposure (adverse effects)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Mexico (epidemiology)</term>
<term>Pilot Projects</term>
<term>Polycyclic Aromatic Hydrocarbons (toxicity)</term>
<term>Polycyclic Aromatic Hydrocarbons (urine)</term>
<term>Respiratory Function Tests</term>
<term>Risk Factors</term>
<term>Surveys and Questionnaires</term>
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<term>Enfant</term>
<term>Enquêtes et questionnaires</term>
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<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Hydrocarbures aromatiques polycycliques (toxicité)</term>
<term>Hydrocarbures aromatiques polycycliques (urine)</term>
<term>Marqueurs biologiques (urine)</term>
<term>Mexique (épidémiologie)</term>
<term>Mâle</term>
<term>Projets pilotes</term>
<term>Tests de la fonction respiratoire</term>
<term>Études transversales</term>
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<keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Polycyclic Aromatic Hydrocarbons</term>
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<keywords scheme="MESH" type="chemical" qualifier="urine" xml:lang="en"><term>Biomarkers</term>
<term>Polycyclic Aromatic Hydrocarbons</term>
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<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Exposition environnementale</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Mexico</term>
</keywords>
<keywords scheme="MESH" qualifier="toxicité" xml:lang="fr"><term>Hydrocarbures aromatiques polycycliques</term>
</keywords>
<keywords scheme="MESH" qualifier="urine" xml:lang="fr"><term>Hydrocarbures aromatiques polycycliques</term>
<term>Marqueurs biologiques</term>
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<term>Child</term>
<term>Cross-Sectional Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Pilot Projects</term>
<term>Respiratory Function Tests</term>
<term>Risk Factors</term>
<term>Surveys and Questionnaires</term>
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<term>Enfant</term>
<term>Enquêtes et questionnaires</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Projets pilotes</term>
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<front><div type="abstract" xml:lang="en">To determine the association of exposure to polycyclic aromatic hydrocarbons (PAHs) with lung function and pH of exhaled breath condensate (EBC) in Mexican schoolchildren.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24500378</PMID>
<DateCreated><Year>2014</Year>
<Month>04</Month>
<Day>08</Day>
</DateCreated>
<DateCompleted><Year>2014</Year>
<Month>12</Month>
<Day>18</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>11</Month>
<Day>25</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1536-5948</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>56</Volume>
<Issue>4</Issue>
<PubDate><Year>2014</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>Journal of occupational and environmental medicine</Title>
<ISOAbbreviation>J. Occup. Environ. Med.</ISOAbbreviation>
</Journal>
<ArticleTitle>Lung function, airway inflammation, and polycyclic aromatic hydrocarbons exposure in mexican schoolchildren: a pilot study.</ArticleTitle>
<Pagination><MedlinePgn>415-9</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1097/JOM.0000000000000111</ELocationID>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To determine the association of exposure to polycyclic aromatic hydrocarbons (PAHs) with lung function and pH of exhaled breath condensate (EBC) in Mexican schoolchildren.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A pilot study was performed in a subsample of 64 schoolchildren from Mexico City. Lung function and pH of EBC were measured and metabolites of PAHs in urine samples were determined. The association was analyzed using robust regression models.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A 10% increase in the concentrations of 2-hydroxyfluorene was significantly negatively associated with forced expiratory volume in 1 second (-11.2 mL, 95% CI: -22.2 to -0.02), forced vital capacity (-11.6 mL, 95% CI: -22.9 to -0.2), and pH of EBC (-0.035, 95% CI: -0.066 to -0.005).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Biomarkers of PAHs exposure were inversely associated with lung function and decrease of ph of EBC as a marker of airway inflammation in Mexican schoolchildren.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Barraza-Villarreal</LastName>
<ForeName>Albino</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>From the National Institute of Public Health (Drs Barraza-Villarreal, Hernandez-Cadena, and Romieu and Ms Escamilla-Nuñez and Ms Schilmann), Cuernavaca, Morelos, Mexico; Centers for Disease Control & Prevention (Drs Li, Romanoff, and Sjödin); Atlanta, Ga; Hospital Infantil de Mexico Federico Gomez (Dr Del Río-Navarro), Mexico DF, Mexico; United States Environmental Protection Agency (Dr Díaz-Sanchez), Research Triangle Park, NC; Universidad Autónoma de San Luis Potosi (Dr Díaz-Barriga), San Luis Potosí, Mexico; Division of Clinical Sciences (Dr Sly), Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Perth; and International Agency for Research on Cancer (Dr Romieu), Lyon, France.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Escamilla-Nuñez</LastName>
<ForeName>Maria Consuelo</ForeName>
<Initials>MC</Initials>
</Author>
<Author ValidYN="Y"><LastName>Schilmann</LastName>
<ForeName>Astrid</ForeName>
<Initials>A</Initials>
</Author>
<Author ValidYN="Y"><LastName>Hernandez-Cadena</LastName>
<ForeName>Leticia</ForeName>
<Initials>L</Initials>
</Author>
<Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Zheng</ForeName>
<Initials>Z</Initials>
</Author>
<Author ValidYN="Y"><LastName>Romanoff</LastName>
<ForeName>Lovisa</ForeName>
<Initials>L</Initials>
</Author>
<Author ValidYN="Y"><LastName>Sjödin</LastName>
<ForeName>Andreas</ForeName>
<Initials>A</Initials>
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<Author ValidYN="Y"><LastName>Del Río-Navarro</LastName>
<ForeName>Blanca Estela</ForeName>
<Initials>BE</Initials>
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<Author ValidYN="Y"><LastName>Díaz-Sanchez</LastName>
<ForeName>David</ForeName>
<Initials>D</Initials>
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<Author ValidYN="Y"><LastName>Díaz-Barriga</LastName>
<ForeName>Fernando</ForeName>
<Initials>F</Initials>
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<Author ValidYN="Y"><LastName>Sly</LastName>
<ForeName>Peter</ForeName>
<Initials>P</Initials>
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<ForeName>Isabelle</ForeName>
<Initials>I</Initials>
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