Analysis of vitamin D levels in patients with and without statin-associated myalgia - a systematic review and meta-analysis of 7 studies with 2420 patients.
Identifieur interne : 002F43 ( PubMed/Checkpoint ); précédent : 002F42; suivant : 002F44Analysis of vitamin D levels in patients with and without statin-associated myalgia - a systematic review and meta-analysis of 7 studies with 2420 patients.
Auteurs : Marta Michalska-Kasiczak [Pologne] ; Amirhossein Sahebkar [Australie] ; Dimitri P. Mikhailidis [Royaume-Uni] ; Jacek Rysz [Pologne] ; Paul Muntner [États-Unis] ; Peter P. Toth [États-Unis] ; Steven R. Jones [États-Unis] ; Manfredi Rizzo [Italie] ; G. Kees Hovingh [Pays-Bas] ; Michel Farnier [France] ; Patrick M. Moriarty [États-Unis] ; Vera A. Bittner [États-Unis] ; Gregory Y H. Lip [Royaume-Uni] ; Maciej Banach [Pologne]Source :
- International journal of cardiology [ 1874-1754 ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
- diagnostic : Myalgie.
- effets indésirables : Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase.
- sang : Marqueurs biologiques, Myalgie, Vitamine D.
- Humains, Myalgie, Étude d'observation comme sujet.
English descriptors
- KwdEn :
- MESH :
- chemical , adverse effects : Hydroxymethylglutaryl-CoA Reductase Inhibitors.
- chemical , blood : Biomarkers, Vitamin D.
- blood : Myalgia.
- chemically induced : Myalgia.
- diagnosis : Myalgia.
- methods : Observational Studies as Topic.
- Humans.
Abstract
Vitamin D (vit D) deficiency may be associated with an increased risk of statin-related symptomatic myalgia in statin-treated patients. The aim of this meta-analysis was to substantiate the role of serum vitamin D levels in statin-associated myalgia.
DOI: 10.1016/j.ijcard.2014.10.118
PubMed: 25464233
Affiliations:
- Australie, France, Italie, Pays-Bas, Pologne, Royaume-Uni, États-Unis
- Alabama, Angleterre, Bourgogne, Bourgogne-Franche-Comté, Grand Londres, Hollande-Septentrionale, Kansas, Maryland, Midlands de l'Ouest
- Amsterdam, Birmingham, Dijon, Londres
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Links to Exploration step
pubmed:25464233Le document en format XML
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Kees Hovingh</name><affiliation wicri:level="3"><nlm:affiliation>Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Vascular Medicine, Academic Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Farnier, Michel" sort="Farnier, Michel" uniqKey="Farnier M" first="Michel" last="Farnier">Michel Farnier</name><affiliation wicri:level="3"><nlm:affiliation>Department of Lipidology, Point Medical, Dijon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Lipidology, Point Medical, Dijon</wicri:regionArea><placeName><region type="region">Bourgogne-Franche-Comté</region><region type="old region">Bourgogne</region><settlement type="city">Dijon</settlement></placeName></affiliation></author><author><name sortKey="Moriarty, Patrick M" sort="Moriarty, Patrick M" uniqKey="Moriarty P" first="Patrick M" last="Moriarty">Patrick M. Moriarty</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Schools of Pharmacy and Medicine, The University of Kansas Medical Center, KS City, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Schools of Pharmacy and Medicine, The University of Kansas Medical Center, KS City</wicri:regionArea><placeName><region type="state">Kansas</region></placeName></affiliation></author><author><name sortKey="Bittner, Vera A" sort="Bittner, Vera A" uniqKey="Bittner V" first="Vera A" last="Bittner">Vera A. 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Lip</name><affiliation wicri:level="3"><nlm:affiliation>University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region></placeName></affiliation></author><author><name sortKey="Banach, Maciej" sort="Banach, Maciej" uniqKey="Banach M" first="Maciej" last="Banach">Maciej Banach</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Poland. Electronic address: maciejbanach@aol.co.uk.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz</wicri:regionArea><wicri:noRegion>Medical University of Lodz</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:25464233</idno><idno type="pmid">25464233</idno><idno type="doi">10.1016/j.ijcard.2014.10.118</idno><idno type="wicri:Area/PubMed/Corpus">003122</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003122</idno><idno type="wicri:Area/PubMed/Curation">003026</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003026</idno><idno type="wicri:Area/PubMed/Checkpoint">003026</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">003026</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Analysis of vitamin D levels in patients with and without statin-associated myalgia - a systematic review and meta-analysis of 7 studies with 2420 patients.</title><author><name sortKey="Michalska Kasiczak, Marta" sort="Michalska Kasiczak, Marta" uniqKey="Michalska Kasiczak M" first="Marta" last="Michalska-Kasiczak">Marta Michalska-Kasiczak</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz</wicri:regionArea><wicri:noRegion>Medical University of Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Sahebkar, Amirhossein" sort="Sahebkar, Amirhossein" uniqKey="Sahebkar A" first="Amirhossein" last="Sahebkar">Amirhossein Sahebkar</name><affiliation wicri:level="1"><nlm:affiliation>Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Metabolic Research Centre, Royal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Metabolic Research Centre, Royal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth</wicri:regionArea><wicri:noRegion>Perth</wicri:noRegion></affiliation></author><author><name sortKey="Mikhailidis, Dimitri P" sort="Mikhailidis, Dimitri P" uniqKey="Mikhailidis D" first="Dimitri P" last="Mikhailidis">Dimitri P. Mikhailidis</name><affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Biochemistry, Royal Free Campus, University College London Medical School, University College London (UCL), London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Biochemistry, Royal Free Campus, University College London Medical School, University College London (UCL), London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Rysz, Jacek" sort="Rysz, Jacek" uniqKey="Rysz J" first="Jacek" last="Rysz">Jacek Rysz</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nephrology, Hypertension and Family Medicine, Chair of Nephrology and Hypertension, Medical University of Lodz, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Nephrology, Hypertension and Family Medicine, Chair of Nephrology and Hypertension, Medical University of Lodz</wicri:regionArea><wicri:noRegion>Medical University of Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Muntner, Paul" sort="Muntner, Paul" uniqKey="Muntner P" first="Paul" last="Muntner">Paul Muntner</name><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL</wicri:regionArea><placeName><region type="state">Alabama</region></placeName></affiliation></author><author><name sortKey="Toth, Peter P" sort="Toth, Peter P" uniqKey="Toth P" first="Peter P" last="Toth">Peter P. Toth</name><affiliation wicri:level="2"><nlm:affiliation>Preventive Cardiology, CGH Medical Center, Sterling, IL, USA; The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Preventive Cardiology, CGH Medical Center, Sterling, IL, USA; The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Jones, Steven R" sort="Jones, Steven R" uniqKey="Jones S" first="Steven R" last="Jones">Steven R. Jones</name><affiliation wicri:level="2"><nlm:affiliation>The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Rizzo, Manfredi" sort="Rizzo, Manfredi" uniqKey="Rizzo M" first="Manfredi" last="Rizzo">Manfredi Rizzo</name><affiliation wicri:level="1"><nlm:affiliation>Biomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Biomedical Department of Internal Medicine and Medical Specialties, University of Palermo</wicri:regionArea><wicri:noRegion>University of Palermo</wicri:noRegion></affiliation></author><author><name sortKey="Kees Hovingh, G" sort="Kees Hovingh, G" uniqKey="Kees Hovingh G" first="G" last="Kees Hovingh">G. Kees Hovingh</name><affiliation wicri:level="3"><nlm:affiliation>Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Vascular Medicine, Academic Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Farnier, Michel" sort="Farnier, Michel" uniqKey="Farnier M" first="Michel" last="Farnier">Michel Farnier</name><affiliation wicri:level="3"><nlm:affiliation>Department of Lipidology, Point Medical, Dijon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Lipidology, Point Medical, Dijon</wicri:regionArea><placeName><region type="region">Bourgogne-Franche-Comté</region><region type="old region">Bourgogne</region><settlement type="city">Dijon</settlement></placeName></affiliation></author><author><name sortKey="Moriarty, Patrick M" sort="Moriarty, Patrick M" uniqKey="Moriarty P" first="Patrick M" last="Moriarty">Patrick M. Moriarty</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Schools of Pharmacy and Medicine, The University of Kansas Medical Center, KS City, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Schools of Pharmacy and Medicine, The University of Kansas Medical Center, KS City</wicri:regionArea><placeName><region type="state">Kansas</region></placeName></affiliation></author><author><name sortKey="Bittner, Vera A" sort="Bittner, Vera A" uniqKey="Bittner V" first="Vera A" last="Bittner">Vera A. Bittner</name><affiliation wicri:level="2"><nlm:affiliation>Division of Cardiovascular Disease, Preventive Cardiology Section, University of Alabama at Birmingham, Birmingham, AL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cardiovascular Disease, Preventive Cardiology Section, University of Alabama at Birmingham, Birmingham, AL</wicri:regionArea><placeName><region type="state">Alabama</region></placeName></affiliation></author><author><name sortKey="Lip, Gregory Y H" sort="Lip, Gregory Y H" uniqKey="Lip G" first="Gregory Y H" last="Lip">Gregory Y H. Lip</name><affiliation wicri:level="3"><nlm:affiliation>University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region></placeName></affiliation></author><author><name sortKey="Banach, Maciej" sort="Banach, Maciej" uniqKey="Banach M" first="Maciej" last="Banach">Maciej Banach</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Poland. Electronic address: maciejbanach@aol.co.uk.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz</wicri:regionArea><wicri:noRegion>Medical University of Lodz</wicri:noRegion></affiliation></author></analytic><series><title level="j">International journal of cardiology</title><idno type="eISSN">1874-1754</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biomarkers (blood)</term><term>Humans</term><term>Hydroxymethylglutaryl-CoA Reductase Inhibitors (adverse effects)</term><term>Myalgia (blood)</term><term>Myalgia (chemically induced)</term><term>Myalgia (diagnosis)</term><term>Observational Studies as Topic (methods)</term><term>Vitamin D (blood)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Humains</term><term>Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase (effets indésirables)</term><term>Marqueurs biologiques (sang)</term><term>Myalgie ()</term><term>Myalgie (diagnostic)</term><term>Myalgie (sang)</term><term>Vitamine D (sang)</term><term>Étude d'observation comme sujet ()</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Hydroxymethylglutaryl-CoA Reductase Inhibitors</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Biomarkers</term><term>Vitamin D</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Myalgia</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Myalgia</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Myalgia</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Myalgie</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Observational Studies as Topic</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Marqueurs biologiques</term><term>Myalgie</term><term>Vitamine D</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Myalgie</term><term>Étude d'observation comme sujet</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Vitamin D (vit D) deficiency may be associated with an increased risk of statin-related symptomatic myalgia in statin-treated patients. The aim of this meta-analysis was to substantiate the role of serum vitamin D levels in statin-associated myalgia.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25464233</PMID><DateCreated><Year>2015</Year><Month>02</Month><Day>02</Day></DateCreated><DateCompleted><Year>2015</Year><Month>08</Month><Day>28</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1874-1754</ISSN><JournalIssue CitedMedium="Internet"><Volume>178</Volume><PubDate><Year>2015</Year><Month>Jan</Month><Day>15</Day></PubDate></JournalIssue><Title>International journal of cardiology</Title><ISOAbbreviation>Int. J. Cardiol.</ISOAbbreviation></Journal><ArticleTitle>Analysis of vitamin D levels in patients with and without statin-associated myalgia - a systematic review and meta-analysis of 7 studies with 2420 patients.</ArticleTitle><Pagination><MedlinePgn>111-6</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ijcard.2014.10.118</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0167-5273(14)02055-5</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Vitamin D (vit D) deficiency may be associated with an increased risk of statin-related symptomatic myalgia in statin-treated patients. The aim of this meta-analysis was to substantiate the role of serum vitamin D levels in statin-associated myalgia.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The search included PUBMED, Cochrane Library, Scopus, and EMBASE from January 1, 1987 to April 1, 2014 to identify studies that investigated the impact of vit D levels in statin-treated subjects with and without myalgia. Two independent reviewers extracted data on study characteristics, methods and outcomes. Quantitative data synthesis was performed using a fixed-effect model.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The electronic search yielded 437 articles; of those 20 were scrutinized as full texts and 13 studies were considered unsuitable. The final analysis included 7 studies with 2420 statin-treated patients divided into subgroups of patients with (n=666 [27.5%]) or without (n=1754) myalgia. Plasma vit D concentrations in the symptomatic and asymptomatic subgroups were 28.4±13.80ng/mL and 34.86±11.63ng/mL, respectively. The combination of data from individual observational studies showed that vit D plasma concentrations were significantly lower in patients with statin-associated myalgia compared with patients not manifesting this side effect (weighted mean difference -9.41ng/mL; 95% confidence interval: -10.17 to -8.64; p<0.00001).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">This meta-analysis provides evidence that low vit D levels are associated with myalgia in patients on statin therapy. Randomized controlled trials are necessary to establish whether vitamin D supplementation reduces the risk for statin-associated myalgia.</AbstractText><CopyrightInformation>Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Michalska-Kasiczak</LastName><ForeName>Marta</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sahebkar</LastName><ForeName>Amirhossein</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Metabolic Research Centre, Royal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mikhailidis</LastName><ForeName>Dimitri P</ForeName><Initials>DP</Initials><AffiliationInfo><Affiliation>Department of Clinical Biochemistry, Royal Free Campus, University College London Medical School, University College London (UCL), London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rysz</LastName><ForeName>Jacek</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Nephrology, Hypertension and Family Medicine, Chair of Nephrology and Hypertension, Medical University of Lodz, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Muntner</LastName><ForeName>Paul</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Toth</LastName><ForeName>Peter P</ForeName><Initials>PP</Initials><AffiliationInfo><Affiliation>Preventive Cardiology, CGH Medical Center, Sterling, IL, USA; The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jones</LastName><ForeName>Steven R</ForeName><Initials>SR</Initials><AffiliationInfo><Affiliation>The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rizzo</LastName><ForeName>Manfredi</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Biomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kees Hovingh</LastName><ForeName>G</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Farnier</LastName><ForeName>Michel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Lipidology, Point Medical, Dijon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moriarty</LastName><ForeName>Patrick M</ForeName><Initials>PM</Initials><AffiliationInfo><Affiliation>Department of Medicine, Schools of Pharmacy and Medicine, The University of Kansas Medical Center, KS City, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bittner</LastName><ForeName>Vera A</ForeName><Initials>VA</Initials><AffiliationInfo><Affiliation>Division of Cardiovascular Disease, Preventive Cardiology Section, University of Alabama at Birmingham, Birmingham, AL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lip</LastName><ForeName>Gregory Y H</ForeName><Initials>GY</Initials><AffiliationInfo><Affiliation>University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Banach</LastName><ForeName>Maciej</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Poland. Electronic address: maciejbanach@aol.co.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group</CollectiveName></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017418">Meta-Analysis</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>10</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Int J Cardiol</MedlineTA><NlmUniqueID>8200291</NlmUniqueID><ISSNLinking>0167-5273</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015415">Biomarkers</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D019161">Hydroxymethylglutaryl-CoA Reductase Inhibitors</NameOfSubstance></Chemical><Chemical><RegistryNumber>1406-16-2</RegistryNumber><NameOfSubstance UI="D014807">Vitamin D</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D015415" MajorTopicYN="N">Biomarkers</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019161" MajorTopicYN="N">Hydroxymethylglutaryl-CoA Reductase Inhibitors</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D063806" MajorTopicYN="N">Myalgia</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName><QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D064887" MajorTopicYN="N">Observational Studies as Topic</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014807" MajorTopicYN="N">Vitamin D</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Myalgia</Keyword><Keyword MajorTopicYN="N">Statin intolerance</Keyword><Keyword MajorTopicYN="N">Statin-associated myalgia</Keyword><Keyword MajorTopicYN="N">Vitamin D</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year><Month>09</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2014</Year><Month>10</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>12</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>12</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>9</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">25464233</ArticleId><ArticleId IdType="pii">S0167-5273(14)02055-5</ArticleId><ArticleId IdType="doi">10.1016/j.ijcard.2014.10.118</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li><li>France</li><li>Italie</li><li>Pays-Bas</li><li>Pologne</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Alabama</li><li>Angleterre</li><li>Bourgogne</li><li>Bourgogne-Franche-Comté</li><li>Grand Londres</li><li>Hollande-Septentrionale</li><li>Kansas</li><li>Maryland</li><li>Midlands de l'Ouest</li></region><settlement><li>Amsterdam</li><li>Birmingham</li><li>Dijon</li><li>Londres</li></settlement></list><tree><country name="Pologne"><noRegion><name sortKey="Michalska Kasiczak, Marta" sort="Michalska Kasiczak, Marta" uniqKey="Michalska Kasiczak M" first="Marta" last="Michalska-Kasiczak">Marta Michalska-Kasiczak</name></noRegion><name sortKey="Banach, Maciej" sort="Banach, Maciej" uniqKey="Banach M" first="Maciej" last="Banach">Maciej Banach</name><name sortKey="Rysz, Jacek" sort="Rysz, Jacek" uniqKey="Rysz J" first="Jacek" last="Rysz">Jacek Rysz</name></country><country name="Australie"><noRegion><name sortKey="Sahebkar, Amirhossein" sort="Sahebkar, Amirhossein" uniqKey="Sahebkar A" first="Amirhossein" last="Sahebkar">Amirhossein Sahebkar</name></noRegion></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Mikhailidis, Dimitri P" sort="Mikhailidis, Dimitri P" uniqKey="Mikhailidis D" first="Dimitri P" last="Mikhailidis">Dimitri P. Mikhailidis</name></region><name sortKey="Lip, Gregory Y H" sort="Lip, Gregory Y H" uniqKey="Lip G" first="Gregory Y H" last="Lip">Gregory Y H. Lip</name></country><country name="États-Unis"><region name="Alabama"><name sortKey="Muntner, Paul" sort="Muntner, Paul" uniqKey="Muntner P" first="Paul" last="Muntner">Paul Muntner</name></region><name sortKey="Bittner, Vera A" sort="Bittner, Vera A" uniqKey="Bittner V" first="Vera A" last="Bittner">Vera A. Bittner</name><name sortKey="Jones, Steven R" sort="Jones, Steven R" uniqKey="Jones S" first="Steven R" last="Jones">Steven R. Jones</name><name sortKey="Moriarty, Patrick M" sort="Moriarty, Patrick M" uniqKey="Moriarty P" first="Patrick M" last="Moriarty">Patrick M. Moriarty</name><name sortKey="Toth, Peter P" sort="Toth, Peter P" uniqKey="Toth P" first="Peter P" last="Toth">Peter P. Toth</name></country><country name="Italie"><noRegion><name sortKey="Rizzo, Manfredi" sort="Rizzo, Manfredi" uniqKey="Rizzo M" first="Manfredi" last="Rizzo">Manfredi Rizzo</name></noRegion></country><country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Kees Hovingh, G" sort="Kees Hovingh, G" uniqKey="Kees Hovingh G" first="G" last="Kees Hovingh">G. Kees Hovingh</name></region></country><country name="France"><region name="Bourgogne-Franche-Comté"><name sortKey="Farnier, Michel" sort="Farnier, Michel" uniqKey="Farnier M" first="Michel" last="Farnier">Michel Farnier</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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